The University of Newcastle, Australia
Available in 2021
Course code

HUBS2209

Units

10 units

Level

2000 level

Course handbook

Description

This course provides learning that builds on knowledge gained in HUBS2206 and involves integrated learning between the areas of Biochemistry, Molecular Biology and Human Genetics. It will cover the underlying molecular and cellular biology involved in carcinogenesis, tumor growth, and metastasis, and the implications of the basic biological findings on cancer prevention, diagnosis, and treatment. Students will also learn about the biologic hallmarks of cancer, genomic instability, dysregulated cancer cell metabolism, and the role of microenvironment, lifestyle factors, and immune system in cancer development and progression. The course is organised as a series of modules that include lectures and practical classes that provides students with a solid background in general cancer biology and prepares them for a career in laboratory-based research in areas of the biomedical sciences.


Availability

Callaghan

  • Semester 1 - 2021

Learning outcomes

On successful completion of the course students will be able to:

1. Describe the biologic hallmarks of cancer.

2. Describe how cell growth and differentiation occurs and what happens when the control of these processes is altered.

3. Describe how cellular processes including cellular metabolism are altered during cancer initiation, progression and metastasis.

4. Describe how genetics and epigenetics drive cancer initiation and progression.

5. Discuss the concepts of cancer stem cells and clonal evolution of cancers.

6. Describe the role of tissue microenvironment, obesity, aging, and lifestyle factors in cancer development.

7. Describe how cancers are modelled and studied in the laboratory.

8. Demonstrate practical skills necessary to conduct laboratory-based investigations of human cancers.

9. Describe how basic biology research helps design novel therapeutics.


Content

This course will cover the following topics:

  1. Cancer cell growth and invasion
  2. Cancer therapeutics
  3. Cancer Genetics
  4. Cancer microenvironment
  5. Cancer stem cells

Requisite

This course replaces HUBS3206. If you have successfully completed HUBS3206 you cannot enrol in this course.


Assumed knowledge

HUBS1403 Biomedical Science Part 1, HUBS1404 Biomedical Science Part 2, HUBS1202 Human Genomics Biomolecular Analysis, HUBS2206 Human Biochemistry and Cell Biology or equivalent.


Assessment items

Quiz: Online Mini Tests x 5

Tutorial / Laboratory Exercises: Laboratory in-prac tests *

In Term Test: In Term Test *

Formal Examination: Formal Examination *

* This assessment has a compulsory requirement.


Compulsory Requirements

In order to pass this course, each student must complete ALL of the following compulsory requirements:

Course Assessment Requirements:

  • Formal Examination: Attempt / Submission Requirement - Students must attempt/submit this assessment item to pass the course.
  • In Term Test: Attempt / Submission Requirement - Students must attempt/submit this assessment item to pass the course.
  • Tutorial / Laboratory Exercises: Attempt / Submission Requirement - Students must attempt/submit this assessment item to pass the course.

Contact hours

Callaghan

Laboratory

Face to Face On Campus 3 hour(s) per Week for 5 Weeks

Lecture

Face to Face On Campus 38 hour(s) per Term Full Term

3 hrs per week for 12 weeks and an examination scheduled during the term