I produced 3 peer-reviewed papers during my postgraduate term. One of them, "BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer" was one of the early publications to show that PALB2 germline mutations are involved in the genetic predisposition to famlial breast cancer, and has ben cited 35 times to date, including by other high-impact publications.
The most notable achievements in my academic career was being awarded the HMRI PhD Student Conference Award, the HMRI Research Higher Degree Support Grant in Medical Innovation and receiving the Faculty Medal from the Faculty of Health for graduating with Honours Class I with excellent undergraduate results.
I am also keen on community involvement, as evident by my participation in various HMRI initiatives. I believe in the importance of creating awareness in the general public about the research being conducted at HMRI.
- Bachelor of Biomedical Sciences (Hons), University of Newcastle, 11/07/2008
- Bachelor of Biomedical Sciences, University of Newcastle, 13/07/2007
- Breast Cancer
- Clinical Genetics
One of my research strengths is in gene sequencing, from primer design to sequencing analysis. I gained this knowledge during my secondment to the Division of Molecular Genetics at Hunter Area Pathology Service (HAPS). I am currently assisting two undergraduate students with their placement project involving sequencing of several genes involved in cancer.
Fields of Research
|110311||Medical Genetics (Excl. Cancer Genetics)||70|
I frequently collaborate with the Molecular Genetics laboratory at Hunter Area Pathology Service, Newcastle
I have previously been a tutor for the Bioinformatics and Functional Genomics (HUBS 2409) course at the University of Newcastle.
Click on a category title below to expand the list of citations for that specific category.
Conference (6 outputs)
|2012||Wong-Brown M, Li S, Wilkins M, Kiejda KA, Bowden NA, Scott R, 'Exploratory targeted resequencing of BRCA1 and BRCA2 in inherited breast cancer', Programme. kConFab Familial Aspects of Cancer: Research & Practice 2012, Kingscliff, NSW (2012) [E3]|
|2012||Gleeson M, Spigelman AD, Meldrum CJ, Dooley S, Wong-Brown M, Young B, et al., 'A case of two mutations in trans in a women diagnosed with breast cancer at the age of 3+0 years', Programme. kConFab Familial Aspects of Cancer: Research & Practice 2012, Kingscliff, NSW (2012) [E3]|
|2012||Wong-Brown M, Li S, Wilkins M, Kiejda KA, Bowden NA, Scott R, 'Targeted resequencing of BRCA1 and BRCA2 in inherited breast cancer', Cancer Research, San Antonio, Texas (2012) [E3]|
|2011||Wong-Brown M, Scott R, Hibberd A, Trevillian PR, Clark D, Meldrum C, 'Measurement of Foxp3 gene expression in renal transplant recipients', Immunology and Cell Biology, Canberra, Australia (2011) [E3]|
|2010||Wong-Brown M, Bowden NA, Forbes JF, Braye SG, Scott R, 'Microsatellite instability (I) in breast tumours', Sydney Cancer Conference 2010. Profiling Risk, Personalising Treatment and Predicting Outcomes. Conference Program and Abstract Book, Sydney, NSW (2010) [E3]|
|2010||Wong-Brown M, Bowden NA, Kiejda KA, Scott R, 'BRIP1 and PALB2 mutation detection in Hunter-New England familial breast cancer cohort', 27th HUGO-IABCR Congress 2010. Genomics, Biology and Breast Cancer Treatment. Programme & Abstract Book, Biopolis, Singapore (2010) [E3]|
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Journal article (7 outputs)
|2014||Wong-Brown MW, Avery-Kiejda KA, Bowden NA, Scott RJ, 'Low prevalence of germline PALB2 mutations in Australian triple-negative breast cancer', International Journal of Cancer, 134 301-305 (2014)|
|2013||Wong-Brown MW, Avery-Kiejda KA, Bowden NA, Scott RJ, 'Low prevalence of germline PALB2 mutations in Australian triple-negative breast cancer', International Journal of Cancer, (2013)|
|2013||Wong-Brown M, Scott R, Mcphillips M, Hipwell M, Pecenpetelovska G, Dooley S, Meldrum C, 'cDNA analysis of the BRCA1 unclassified variant c.5194-12G>A', Clinical Genetics, 84 505-506 (2013)|
|2011||Wong-Brown M, Nordfors C, Mossman D, Pecenpetelovska G, Kiejda KA, Talseth-Palmer B, et al., 'BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer', Breast Cancer Research and Treatment, 127 853-859 (2011) [C1]|
|2011||Kiejda KA, Wong-Brown M, Scott R, 'Genetic markers in breast cancer - How far have we come from BRCA1?', Asia-Pacific Journal of Molecular Medicine, 1 1-15 (2011) [C1]|
|2011||Zacharin M, Bajpai A, Chow CW, Catto-Smith A, Stratakis C, Wong-Brown M, Scott R, 'Gastrointestinal polyps in McCune Albright syndrome', Journal of Medical Genetics, 48 458-461 (2011) [C1]|
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Grants and Funding
|Number of grants||1|
For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.
Click on a grant title below to expand the full details for that specific grant.
2014 (1 grants)
Targeted next-generation sequencing of potential breast cancer susceptibility genes$30,000
Funding Body: Hunter Medical Research Institute
|Number of current supervisions||0|
Mrs Michelle Wong-Brown
|Work Phone||(02) 4042 0321|
|Fax||(02) 4042 0031|
Centre for Information-Based Medicine
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine
The University of Newcastle, Australia
HMRI Level 3 West,
Hunter Medical Research Institute,
Hunter Medical Research Institute