Dr Md Reduanul Hossain

Dr Md Reduanul Hossain is an Early Career Researcher within the Mothers and Babies Research Program (MBRP) at the School of Medicine and Public Health. He completed his PhD in Reproductive Medicine at the University of Newcastle, Australia, and both his Master of Philosophy and Master of Pharmaceutical Science degrees from the University of Greenwich, UK.

During his PhD, Dr Hossain worked on a project aimed at developing therapeutic interventions to safely and effectively prevent preterm birth. He focused on the ongoing development of a uterine-targeted drug delivery system, which represents a novel strategy for preventing preterm birth while ensuring the safety of the treatment for both the pregnant mother and the unborn baby. Furthermore, Dr Hossain utilised biopsies of pregnant human uterine tissue to identify synergistic drug combinations that enhance the effectiveness of tocolytics, allowing for better outcomes with lower drug dosages. Dr Hossain successfully identified eight novel drug combinations that exhibit synergistic effects in inhibiting contractions in pregnant human uterine tissues. After completing his PhD in 2023, Dr Hossain began working on a research project focused on developing precision medicine for gynaecological cancers. During his postdoctoral training, he established several preclinical models, including cancer patient-derived xenografts and organoid models, designed to study cancer progression, metastasis, and recurrence. Using these models, he conducted drug screening efforts to identify treatments for patients with gynaecological cancer. Dr Hossain has recently returned to the MBRP group, where he currently serves as a Research Fellow. He is working on two impactful reproductive medicine projects: one involves encapsulating novel synergistic drug combinations into a nanoparticle-based uterine-targeted drug delivery system, and the other investigates the role of placental exosomes in promoting uterine contractility.