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Dr Logeshwaran Panneerselvan

Research Associate

Global Centre for Environmental Remediation

Career Summary

Biography

My research expertise over last 5 years has been on the environmental remediation of organophosphorus compounds and polycyclic aromatic hydrocarbons (PAHs) by bacteria. I was awarded with International Post Graduate Research Scholarship (IPRS) by Commonwealth of Australia to conduct my research at the Centre for Environmental Risk Assessment and Remediation (CERAR), University of South Australia, on the enzymatic detoxification of organophosphorus pesticides, Fenamiphos and Malathion by Microbacterium sp. MM1 under the supervision of Prof. Megharaj Mallavarapu, Dr. Kannan Krishnan and Prof. Ravi Naidu. My PhD research has demonstrated that the enzymes isolated from Microbacterium sp. MM1 was capable of efficient detoxification of organophosphorus compounds and polycyclic aromatic hydrocarbons. As a world’s first report, I have successfully purified and identified enzyme capable of detoxifying organophosphorus neurotoxic compounds. Gene(s) responsible for the degradation of environmental pollutants have been characterised. Molecular docking and dynamics studies conducted with the homology modelled enzyme from Microbacterium sp. MM1 has showed potential binding with chemical warfare agents. Due to the promising nature of the enzyme that can be used for the detoxification of stock pile chemical warfare agents particularly “V-type” nerve agents, a preliminary provisional patent application has been submitted to the patenting authority and I am expecting to get the approval for provisional patent anytime soon. Alongside the hydrolytic pathways of potential enzymes capable of detoxifying other structurally similar pollutants are being currently explored through site-directed mutagenesis.

After completing my PhD, I got an opportunity to work as Research Assistant at the Cooperative Research Centre for Contamination Risk Assessment and Remediation (CRC-CARE) at the University of South Australia on the eco and genotoxicity of fluorinated Class B and bush firefighting compounds to aquatic invertebrates (Daphnia carinata), aquatic plants (Lemna minor. L.), fishes (Danio rerio), earthworms (Eisenia fetida). From the results it is evident that both fluorinated and non-fluorinated firefighting products cause both ecotoxicity and genotoxicity to the test organism.

Prior to commencing PhD at University of South Australia, I was twice employed as a Senior Research Fellow at Tamil Nadu Agricultural University. One of the project aimed at assessing the long term impact of distillery effluent application to soil and crop potential funded by Sakthi Sugars, India. During the period of employment (October 2008 to February 2009), Soil and water analysis and characterization was done in more than 500 sites and a field trail was carried out  with maize (Zea mays) crop irrigated with various combination of distillery effluent showed positive relationship in terms of growth and yield with respect to the increasing concentration of effluent. Another project entitled “IPM-CRSP Research and Education in South Asia” funded by Virginia Tech, USA and USAID. During this employment (September 2007 to June 2008), I was involved in the identification of Cry proteins in Bacillus thuringiensis transformed egg plants using immuno strips and also performing bioassays with neonates of Lepidoptera and Spodoptera. Also assisted professors with preparation of laboratory manual and conducting laboratory sessions for the course “ABT 404 – Industrial Biotechnology” for B.Tech in Biotechnology students at TNAU, India.

I have completed my postgraduate diploma in nanobiotechnology through Life Science Foundation of India, Karanataka, India. I have completed my Master in Agricultural Microbiology in 2007 from Tamil Nadu Agricultural University. My Master’s thesis entitled “Assessment on bio-control properties and plant growth promoting potential of Gluconacetobater diazotrophicus”. I have obtained an overall grade point average (OGPA) of 9.06 out of 10.0. My undergraduate degree was in Horticulture in 2005 from Tamil Nadu Agricultural University with an OGPA of 9.39 out of 10.0.


Qualifications

  • PhD, University of South Australia
  • Bachelor of Science, Tamil Nadu Agricultural University Coimbatore
  • Master of Science (Agriculture), Tamil Nadu Agricultural University Coimbatore
  • Graduate Diploma, Life Science Foundation India Karnataka

Keywords

  • Microbiology
  • Molecular Toxicology
  • Molecular biology
  • Proteomics

Languages

  • Tamil (Working)
  • English (Fluent)

Fields of Research

Code Description Percentage
060702 Plant Cell and Molecular Biology 25
100203 Bioremediation 25
060599 Microbiology not elsewhere classified 50

Professional Experience

UON Appointment

Title Organisation / Department
Research Associate University of Newcastle
Global Centre for Environmental Remediation
Australia

Professional appointment

Dates Title Organisation / Department
13/09/2013 - 6/03/2015 Research Assistant

Ecotoxicological studies in aqueous fluorinated and bush firefighting compound to soil microbes, earth worms, aquatic invertebrates, aquatic plants and fishes.

University of South Australia
ITEE
Australia
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Journal article (3 outputs)

Year Citation Altmetrics Link
2017 Subashchandrabose SR, Logeshwaran P, Venkateswarlu K, Naidu R, Megharaj M, 'Pyrene degradation by Chlorella sp MM3 in liquid medium and soil slurry: Possible role of dihydrolipoamide acetyltransferase in pyrene biodegradation', ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 23 223-232 (2017) [C1]
DOI 10.1016/j.algal.2017.02.010
Co-authors Suresh Subashchandrabose, Megh Mallavarapu, Ravi Naidu
2016 Panneerselvan L, Sivaram AK, Mallavarapu M, Naidu R, 'Evaluation of cyto- and genotoxic effects of Class B firefighting foam products: Tridol-S 3% AFFF and Tridol-S 6% AFFF to Allium cepa', Environmental Technology and Innovation, 6 185-194 (2016) [C1]

© 2016 Worldwide a multitude of firefighting compounds are currently used for the mitigation and protection of man-made structures and forests alike from fire damages. Among the ... [more]

© 2016 Worldwide a multitude of firefighting compounds are currently used for the mitigation and protection of man-made structures and forests alike from fire damages. Among the class of firefighting agents, Class B firefighting foams are generally used to control fires generated from hydrocarbon liquids. In the present study, we assessed the cyto- and genotoxicity of two widely used class B firefighting foam concentrates, Tridol-S 3% and Tridol-S 6% to Alliumcepa through chromosomal aberration and comet assay using root meristem cells. A. cepa root tips were exposed to Tridol-S 3% and Tridol-S 6% with six different concentrations (0%, 0.005%, 0.01%, 0.02%, 0.03%, 0.04% and 0.05%) for 24 h. Cytogenetic effect endpoints such as mitotic index, and chromosomal aberrations were observed. Chromosomal aberrations in the control (untreated onion root tips) was negligible with the mitotic index (MI) value of 79.6%, while the MI significantly decreased in all the test concentrations of firefighting compounds. Genotoxicity assessment through comet assay also revealed that both the products were genotoxic with a significant increase in per cent tail DNA and olive tail moment. Among the test compounds, Tridol-S 3% was more toxic than Tridol-S 6%. To our knowledge, this is the first study on the cyto- and genotoxic effects of class B firefighting foams to A. cepa root meristem cells. This study also suggests that the toxicological studies using A. cepa root meristem cells can be employed for evaluating the toxicological impacts of firefighting foams in the environment.

DOI 10.1016/j.eti.2016.10.003
Co-authors Megh Mallavarapu, Ravi Naidu
2016 Prasath A, Panneerselvan L, Provatas A, Naidu R, Megharaj M, 'Genotoxicity assessment of acute exposure of 2, 4-dinitroanisole, its metabolites and 2, 4, 6-trinitrotoluene to Daphnia carinata', ECOTOXICOLOGY, 25 1873-1879 (2016) [C1]
DOI 10.1007/s10646-016-1709-8
Co-authors Ravi Naidu, Prasath Annamalai, Megh Mallavarapu

Conference (1 outputs)

Year Citation Altmetrics Link
2015 Krishnan K, Megharaj M, Mayilswami S, Sivaram AK, Panneerselvan L, Naidu R, 'Perfluorooctane Sulfonate (PFOS) And Perfluorooctanoic Acid (PFOA): Ecotoxicity And Environmental Concerns.' (2015)
Co-authors Ravi Naidu, Kannan Krishnan
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Grants and Funding

Summary

Number of grants 4
Total funding $174,661

Click on a grant title below to expand the full details for that specific grant.


20171 grants / $155,154

Risk based management of petroleum hydrocarbon contaminated groundwater$155,154

Funding body: CRC CARE Pty Ltd

Funding body CRC CARE Pty Ltd
Project Team Professor Megh Mallavarapu, Doctor Logeshwaran Panneerselvan, Professor Ravi Naidu, Dr Sreenivasulu Chadalavada
Scheme Research Project
Role Investigator
Funding Start 2017
Funding Finish 2018
GNo G1700320
Type Of Funding CRC - Cooperative Research Centre
Category 4CRC
UON Y

20161 grants / $5,000

New Staff Grant$5,000

Funding body: Faculty of Science and Information Technology, The University of Newcastle | Australia

Funding body Faculty of Science and Information Technology, The University of Newcastle | Australia
Project Team

Logeshwaran Panneerselvan, Megharaj Mallavarapu, Ravi Naidu

Scheme New Staff Grant
Role Lead
Funding Start 2016
Funding Finish 2016
GNo
Type Of Funding Internal
Category INTE
UON N

20152 grants / $14,507

PERSISTENT ORGANIC POLLUTANTS in WATER, SEDIMENT and BIOTA$8,000

Funding body: Lake Macquarie City Council

Funding body Lake Macquarie City Council
Project Team Doctor Kannan Krishnan, Doctor Logeshwaran Panneerselvan, Doctor Suresh Subashchandrabose, Doctor Thava Palanisami, Professor Megh Mallavarapu
Scheme Lake Macquarie Environmental Research Grant
Role Investigator
Funding Start 2015
Funding Finish 2015
GNo G1600058
Type Of Funding Other Public Sector - Local
Category 2OPL
UON Y

Microplastics in Lake Macquarie: Distribution, Characteristics $6,507

Funding body: Lake Macquarie City Council

Funding body Lake Macquarie City Council
Project Team Doctor Thava Palanisami, Doctor Suresh Subashchandrabose, Doctor Logeshwaran Panneerselvan, Doctor Kannan Krishnan, Professor Megh Mallavarapu
Scheme Lake Macquarie Environmental Research Grant
Role Investigator
Funding Start 2015
Funding Finish 2015
GNo G1600173
Type Of Funding Other Public Sector - Local
Category 2OPL
UON Y
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Dr Logeshwaran Panneerselvan

Position

Research Associate
Global Centre for Environmental Remediation
Global Centre for Environmental Remediation
Faculty of Science

Contact Details

Email logeshwaran.panneerselvan@newcastle.edu.au
Phone (02) 4913 8739

Office

Room ATC
Building Advanced Technology Centre.
Location Callaghan
University Drive
Callaghan, NSW 2308
Australia
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