| 2025 |
Brain D, Sivapragasam N, Browne K, White NM, Russo PL, Cheng AC, Stewardson AJ, Matterson G, Tehan PE, Graham K, Amin M, Kiernan M, King J, Mitchell BG, 'Economic Evaluation of Enhanced Cleaning and Disinfection of Shared Medical Equipment', JAMA Network Open, 8 (2025) [C1]
Importance: The economic value of cleaning and disinfection of shared medical equipment is currently unknown. Objective: To evaluate whether or not better environmental... [more]
Importance: The economic value of cleaning and disinfection of shared medical equipment is currently unknown. Objective: To evaluate whether or not better environmental cleaning and disinfection of shared medical equipment would be cost-effective compared with usual care. Design, Setting, and Participants: This economic evaluation study was a within-trial cost-effectiveness analysis of a stepped-wedge cluster randomized clinical trial: the Cleaning and Enhanced Disinfection (CLEEN) study. The trial included 5002 inpatients and was conducted in 10 adult acute-care wards at a tertiary hospital in Australia between March 20, 2023, and November 24, 2023. The evaluation takes a hospital costing perspective. A decision-tree model was developed to evaluate the intervention; costs are presented in Australian dollars. Statistical analysis was performed from May to October 2024. Interventions: A multimodal cleaning intervention was introduced during the intervention, focusing on additional cleaning hours, education, audit, and feedback. The control group received usual care, including routine cleaning by clinical staff. Main Outcomes and Measures: Incremental cost-effectiveness ratio, where the mean change to costs associated with the intervention is divided by the mean change in outcomes. Results: This study assessed 5002 patients (2478 [49.5%] male, 2524 [50.5%] female [50.5%]; mean [SD] age, 71.6 [16.1] years). For a cohort of 1000 patients at risk of health care-associated infection (HAI), the estimated total costs associated with the intervention were $1513300, compared with $2155310 for usual care. The estimated number of HAIs was 100 in the intervention group, compared with 130 for the usual care group. Compared with usual care, the intervention was associated with reduced HAIs and costs, with a 90.5% chance that intervention adoption was cost-saving. This probability increased to 99.9% if a decision-maker was willing to pay $20000 to avoid an infection. Conclusions and Relevance: In this economic evaluation study of enhanced cleaning and disinfection of shared medical equipment, the intervention resulted in reduced HAIs and a $642010 reduction in costs per 1000 patients, compared with the control group. These results suggest that the CLEEN intervention is a cost-saving initiative.
|
|
|
| 2024 |
Barker M-E, King J, Mitchell B, Dawson A, Crowfoot G, 'The effect of hospital volunteering on empathy in nursing and medical students', COLLEGIAN, 31, 34-39 (2024) [C1]
Background: Empathic care benefits patients and healthcare providers. There is evidence of self-reported empathy decline among students in healthcare education. Hospita... [more]
Background: Empathic care benefits patients and healthcare providers. There is evidence of self-reported empathy decline among students in healthcare education. Hospital volunteering could assist undergraduate healthcare students to develop empathetic relationships with patients. Aim: The study aimed to investigate the feasibility and effect of a hospital volunteering intervention on the empathy levels of undergraduate nursing and medical students. It further aimed to explore their experience of the intervention and determine student-identified areas for patient safety improvements. Design: Pre¿post-intervention study Setting: A large outer metropolitan hospital in New South Wales, Australia. Participants: Twenty-nine (n = 29) undergraduate nursing and medical students from an Australian university. Methods: Students had an introductory experience of volunteering at their local district hospital through participation in the 'Volunteer Taster Program'. The Jefferson Scale of Empathy-Health Professions Student questionnaire was used to measure student empathy scores pre and post program. Responses to open-ended questions were thematically analysed to evaluate student experiences and identify student-reported areas for patient safety improvements. Results: Twenty-nine students (18 nursing, 11 medical) completed the program. Students had statistically significant improvements in post-intervention mean empathy scores 112.03 (95% CI 107.56, 116.5) to 117.38 (95% CI 113.76, 121.00) p < 0.001. Subgroup analysis identified a larger increase in empathy scores among medical students than nursing students. The thematic analysis revealed potential program benefits, including new perspectives of the patient experience, improved confidence in patient communication, a stronger professional identity, and a rewarding experience. Identified patient safety issues included concerns for patients' emotional and physical well-being, and patient communication. Conclusions: The Volunteer Taster Program is feasible and enabled nursing and medical students to connect with patients outside the sphere of clinical education. It appears to increase empathy levels in undergraduate students and could assist them to deliver empathetic, person-centred healthcare.
|
|
Open Research Newcastle |
| 2024 |
Browne K, White NM, Russo PL, Cheng AC, Stewardson AJ, Matterson G, Tehan PE, Graham K, Amin M, Northcote M, Kiernan M, King J, Brain D, Mitchell BG, 'Investigating the effect of enhanced cleaning and disinfection of shared medical equipment on health-care- associated infections in Australia (CLEEN): a stepped-wedge, cluster randomised, controlled trial', LANCET INFECTIOUS DISEASES, 24, 1347-1356 (2024) [C1]
|
|
Open Research Newcastle |
| 2023 |
Browne K, White N, Tehan P, Russo PL, Amin M, Stewardson AJJ, Cheng AC, Graham K, O'Kane G, King J, Kiernan M, Brain D, Mitchell BG, 'A randomised controlled trial investigating the effect of improving the cleaning and disinfection of shared medical equipment on healthcare-associated infections: the CLEaning and Enhanced disiNfection (CLEEN) study', TRIALS, 24 (2023) [C1]
Background: Healthcare-associated infections (HAIs) are a common, costly, yet largely preventable complication impacting patients in healthcare settings globally. Impro... [more]
Background: Healthcare-associated infections (HAIs) are a common, costly, yet largely preventable complication impacting patients in healthcare settings globally. Improving routine cleaning and disinfection of the hospital environment has been shown to reduce the risk of HAI. Contaminated shared medical equipment presents a primary transmission route for infectious pathogens, yet is rarely studied. The CLEEN study will assess how enhanced cleaning and disinfection of shared medical equipment affects the rate of HAIs in a tertiary hospital setting. The initiative is an evidence-based approach combining staff training, auditing and feedback to environmental services staff to enhance cleaning and disinfection practices. Methods: The CLEEN study will use a stepped wedge randomised controlled design in 10 wards of one large Australian hospital over 36¿weeks. The intervention will consist of 3 additional hours per weekday for the dedicated cleaning and disinfection of shared medical equipment on each ward. The primary outcome is to demonstrate the effectiveness of improving the quality and frequency of cleaning shared medical equipment in reducing HAIs, as measured by a HAI point prevalence study (PPS). The secondary outcomes include the thoroughness of equipment cleaning assessed using fluorescent marker technology and the cost-effectiveness of the intervention. Discussion: Evidence from the CLEEN study will contribute to future policy and practice guidelines about the cleaning and disinfection of shared medical equipment. It will be used by healthcare leaders and clinicians to inform decision-making and implementation of best-practice infection prevention strategies to reduce HAIs in healthcare facilities. Trial registration: Australia New Zealand Clinical Trial Registry ACTRN12622001143718.
|
|
Open Research Newcastle |
| 2022 |
Barker M-E, Crowfoot G, King J, 'Empathy development and volunteering for undergraduate healthcare students: A scoping review', NURSE EDUCATION TODAY, 116 (2022) [C1]
|
|
Open Research Newcastle |
| 2020 |
Parker V, Giles M, King J, Bantawa K, 'Barriers and facilitators to implementation of a multifaceted nurse-led intervention in acute care hospitals aimed at reducing indwelling urinary catheter use: A qualitative study', JOURNAL OF CLINICAL NURSING, 29, 3042-3053 (2020) [C1]
|
|
Open Research Newcastle |
| 2020 |
Giles M, Graham L, Ball J, King J, Watts W, Harris A, Oldmeadow C, Ling R, Paul M, O'Brien A, Parker V, Wiggers J, Foureur M, 'Implementation of a multifaceted nurse-led intervention to reduce indwelling urinary catheter use in four Australian hospitals: A cluster controlled study.', Journal of clinical nursing, 29, 872-887 (2020) [C1]
|
|
Open Research Newcastle |
| 2020 |
Purcell A, Buckley T, King J, Moyle W, Marshall AP, 'Topical Analgesic and Local Anesthetic Agents for Pain Associated with Chronic Leg Ulcers: A Systematic Review', ADVANCES IN SKIN & WOUND CARE, 33, 240-251 (2020) [C1]
|
|
|
| 2019 |
Giles M, Graham L, Ball J, Watts W, King J, Bantawa K, Paul M, Harris A, O'Brien AP, Parker V, 'Variations in indwelling urinary catheter use in four Australian acute care hospitals', JOURNAL OF CLINICAL NURSING, 28, 4572-4581 (2019) [C1]
Aims and objectives: To identify the point prevalence of indwelling urinary catheters (IDCs) in adult inpatients in acute care hospitals, and to describe the indication... [more]
Aims and objectives: To identify the point prevalence of indwelling urinary catheters (IDCs) in adult inpatients in acute care hospitals, and to describe the indications for IDC insertion based on patient age, gender, specialty and hospital. Background: Catheter-associated urinary tract infections (CAUTIs) are preventable healthcare-associated infections. IDC duration is the strongest predictor of CAUTI, and little is known about characteristics of patients who receive an IDC. Design: Two single-day point prevalence surveys collected baseline patient data as part of a larger pre-post control-intervention study. Methods: Surveys were conducted at four acute care hospitals in NSW, Australia, for all adult patients. Data collection included IDC presence, insertion details and urine culture collection. Point prevalence data were linked with electronically extracted patient demographic data. This study is presented in line with STROBE checklist (See Supplementary File 1). Result: Data from 1,630 patients were analysed, with 196 patients (12%) identified as having an IDC on the survey dates. IDC prevalence rates were higher in males (13%) than in females (11%). Critical care had the highest rate of patients with IDCs (42%). Urine cultures were collected in 70 patients with an IDC (43%). Conclusions: Findings indicated similar rates of IDC use in males and females, and there was no significant difference in age between patients with or without an IDC. However, indication for IDC varied by patient age and gender. High rates of urine culture collection may represent routine collection. Relevance to clinical practice: IDC use is found across genders, all age groups and specialties. Nurses should be aware that any of their patients may have an IDC and be particularly aware of certain indications based on patient age and gender. Routine urine culture collection is not advised, and instead, nurses should be guided by clinical decision-making tools.
|
|
Open Research Newcastle |
| 2018 |
Purcell A, Buckley T, King J, Moyle W, Marshall AP, 'Eutectic mixture of local anaesthetics (EMLA®) as a primary dressing on painful chronic leg ulcers: A pilot randomised controlled trial', Pilot and Feasibility Studies, 4 (2018) [C1]
|
|
|
| 2017 |
Colgan J, Jeong S, Hickey N, King J, 'The Clinical Nurse Consultant role in incident surveillance and patient safety: A case report', COLLEGIAN, 24, 463-468 (2017) [C1]
The Clinical Nurse Consultant (CNC) role emerged in New South Wales, Australia in 1986 as an advanced practice position. There is a growing body of literature seeking t... [more]
The Clinical Nurse Consultant (CNC) role emerged in New South Wales, Australia in 1986 as an advanced practice position. There is a growing body of literature seeking to articulate the multifaceted roles and responsibilities of the CNC within the Australian context. In this paper, we present a clinical case report that demonstrates how high risk medication administration errors via newly implemented syringe driver pumps, were identified and managed by a CNC. The CNC role was central in the identification of this series of medication errors that occurred across a number of hospitals, although these incidents could have been dismissed as human error. This report outlines the investigation, incident management process and subsequent release of a NSW state-wide Safety Alert. It also provides a discussion on the three key components for the successful management of a clinical incident investigation: leadership, teamwork and a 'no blame' culture. The specific role of the CNC in this case report provides evidence that the role of the CNC is pivotal to patient safety.
|
|
|
| 2017 |
Purcell A, Buckley T, Fethney J, King J, Moyle W, Marshall AP, 'The Effectiveness of EMLA as a Primary Dressing on Painful Chronic Leg Ulcers: A Pilot Randomized Controlled Trial', ADVANCES IN SKIN & WOUND CARE, 30, 354-363 (2017) [C1]
|
|
|
| 2017 |
Purcell A, Buckley T, Fethney J, King J, Moyle W, Marshall AP, 'The Effectiveness of EMLA as a Primary Dressing on Painful Chronic Leg Ulcers: Effects on Wound Healing and Health-Related Quality of Life', INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS, 16, 163-172 (2017) [C1]
|
|
|
| 2015 |
King J, Overland J, Fisher M, White K, 'Severe Hypoglycemia and the Role of the Significant Other Expert, Sentry, and Protector', DIABETES EDUCATOR, 41, 698-705 (2015)
Purpose The purpose of the study was to gain a better understanding of what severe hypoglycemia means to significant others. Narrative inquiry methodology was utilized.... [more]
Purpose The purpose of the study was to gain a better understanding of what severe hypoglycemia means to significant others. Narrative inquiry methodology was utilized. In-depth interviews were conducted with 7 significant others of adults with type 1 diabetes about their experience with severe hypoglycemia. Interviews were recorded, transcribed verbatim, and then developed into narrated core stories through a process of selecting and organizing events and by describing the relationship among these events. This was followed by thematic analysis to reveal the shared narrative of significant others. Episodes of severe hypoglycemia were found to turn the participants' lives upside down. The inability of the individual with diabetes to manage severe hypoglycemia required the significant other to detect and treat these episodes. The theme "managing disruption" captured how the significant others' role shifted from one of background support to an active, primary role in severe hypoglycemia management. They became (1) the expert by arming themselves with knowledge and skills to assist with the severe hypoglycemia episodes, (2) the sentry by becoming more vigilant and prepared for these episodes, and (3) the protector of the person with diabetes by shielding him or her from the vulnerable position that the severe hypoglycemia episodes placed one in. This study highlights the important role that significant others play in the management of severe hypoglycemia. It also emphasizes the need for health care professionals to provide appropriate education and support. © 2015, SAGE Publications. All rights reserved.
|
|
|
| 2012 |
Kinsella JM, Barker G, King J, Webber MGT, Boyd M, Ho KWK, Gallagher R, 'Implementing point of care blood ketone testing in the Emergency Department', Australasian Emergency Nursing Journal, 15, 63-67 (2012)
Background: Rapid and accurate testing of blood ketone levels (BKL) can assist in the assessment of insulin insufficiency and detection of diabetic ketoacidosis (DKA) i... [more]
Background: Rapid and accurate testing of blood ketone levels (BKL) can assist in the assessment of insulin insufficiency and detection of diabetic ketoacidosis (DKA) in the acute care setting. We assessed the potential for introducing point of care measurement of BKL into an Australian emergency department. Methods: After providing informed consent, 72 patients (80 separate presentations) with insulin-requiring diabetes who presented to an emergency department with hyperglycaemia (capillary blood glucose level of =10.0. mmol/L) underwent testing for BKL at triage. Staff were guided by a protocol developed for interpretation of elevated BKL = 1.0. mmol/L and subsequent actions. Urine ketones and arterial blood gas testing occurred as usual. Time to testing was recorded for all measures. Results: BKL testing occurred immediately in 91% of the presentations, whereas urine ketones and arterial blood gas testing was uncommon (24% and 15% respectively) and not immediate. Elevated BKL (=1.0. mmol/L) occurred in 17% of presentations, of whom five were diagnosed with DKA within the Emergency Department. However, testing for BKL decreased over the duration of the study. Patients most frequently tested for BKL were younger (58.59 years) than patients who were not tested (79.5 years) (p= .011). Conclusions: Implementation of point of care BKL testing in the Emergency Department can assist in the detection of significant numbers of patients with insulin insufficiency, however, ongoing education and support is required to sustain the change in practice. © 2012.
|
|
|
| 2012 |
Purcell A, Marshall A, King J, Buckley T, 'Eutectic mixture of local anaesthetics (EMLA) 5% cream as a primary dressing on a painful lower leg ulcer', JOURNAL OF WOUND CARE, 21, 309-+ (2012)
|
|
|
| 2010 |
Fisher MJ, King J, 'The self-directed learning readiness scale for nursing education revisited: A confirmatory factor analysis', NURSE EDUCATION TODAY, 30, 44-48 (2010)
|
|
|
| 2009 |
King J, Redmond M, Kinsella J, Gallagher R, McElhone B, Tuch B, 'Using educational DVDs to increaseknowledge about diabetes cell therapies', Journal of Diabetes Nursing, 13, 70-77 (2009)
The ultimate goal of research into type 1 diabetes is to find a cure. There are currently a number of research strategies under investigation to meet this goal, which a... [more]
The ultimate goal of research into type 1 diabetes is to find a cure. There are currently a number of research strategies under investigation to meet this goal, which aim to replace the destroyed insulin-producing beta-cells of the pancreas. It is important that people with type 1 diabetes and their healthcare professionals keep informed about these advances in research, as it can provide motivation to maintain diabetes self-management behaviour. This article presents the findings of an Australian study which evaluated the effectiveness of a DVD developed as an educational tool to provide information to people with type 1 diabetes, their families and healthcare professionals on the latest advances in islet-cell therapy.
|
|
|
| 2008 |
King J, Mitchelhill I, Fisher MJ, 'Development of the congenital adrenal hyperplasia knowledge assessment questionnaire (CAHKAQ)', JOURNAL OF CLINICAL NURSING, 17, 1689-1696 (2008)
|
|
|
| 2007 |
King J, Hardie K, Conway JF, 'The perceptions of high school careers advisers regarding nursing: An Australian study', Contemporary Nurse, 24, 137-146 (2007) [C1]
|
|
|
| 2005 |
Mangone N, King J, Croft T, Church J, 'Group debriefing: an approach to psychosocial support for New Graduate Registered Nurses and Trainee Enrolled Nurses.', Contemporary Nurse A Journal for the Australian Nursing Profession, 20, 248-257 (2005)
The transition from student to an accountable health professional is a difficult time for the novice nurse and can result in significant anxiety, stress and poor social... [more]
The transition from student to an accountable health professional is a difficult time for the novice nurse and can result in significant anxiety, stress and poor socialisation into the nursing profession. A strategy applied at a major tertiary teaching hospital to address transitional issues for novice nurses is that of group debriefing sessions. This qualitative study used focus groups to explore the effectiveness of these debriefing sessions for new graduate nurses and trainee enrolled nurses. The results demonstrated that the sessions provided nurses with a supportive environment, access to peer support and a sense of belonging. This provided an opportunity to develop confidence in their nursing competence and improvement in interpersonal communication skills. Debriefing sessions are an effective psychosocial support mechanism that can ameliorate the 'reality shock' experienced by nurses in their first year of practice. Group debriefing is an important component in the transitional support process and should be used to complement other strategies to enhance the psychosocial experiences of novice nurses.
|
|
|
| 2002 |
Fisher M, Brown L, King J, 'Perceptions and expectations of nursing: Changes in first year nursing', Focus on Health Professional Education, 4, 21-32 (2002)
|
|
|
| 2001 |
Fisher M, King J, Tague G, 'Development of a self-directed learning readiness scale for nursing education', Nurse Education Today, 21, 516-525 (2001)
Self-directed learning is a method of instruction used increasingly in adult education. A scale was developed in response to a need for a valid and reliable instrument ... [more]
Self-directed learning is a method of instruction used increasingly in adult education. A scale was developed in response to a need for a valid and reliable instrument to measure self-directed learning readiness. Such a scale will allow nurse educators to diagnose students' attitudes, abilities and personality characteristics, necessary for self-directed learning. This study was undertaken in two stages. In the first, the Delphi technique utilizing a panel of 11 nurse educator experts was used to assess the content and construct validity of a number of items perceived to reflect self-directed learning readiness. Each panel member was asked to independently rate the relevance of each item on a Likert scale. The second stage involved the administration of the questionnaire to a convenience sample of 201 undergraduate nursing students. The questionnaire was analysed using principal components factor analysis with varimax rotation, Chronbach's coefficient alpha, and item-to-total correlations to measure the scale's construct validity, internal consistency (reliability), and unidimensionality, respectively. The resulting self-directed learning readiness scale appears homogeneous and valid. The scale will assist nurse educators in the diagnosis of student learning needs, in order for the educator to implement teaching strategies that will best suit the students. Furthermore the development of this scale will provide valuable data for curriculum development. © 2001 Harcourt Publishers Ltd.
|
|
|
| 2001 |
Thorburn J, Dean M, Finn T, King J, Wilkinson M, 'Student learning through video assessment.', Contemporary Nurse A Journal for the Australian Nursing Profession, 10, 39-45 (2001)
This paper reports on the use of video and self-assessment as a tool to guide and support undergraduate students in the practice of nursing. This method of learning and... [more]
This paper reports on the use of video and self-assessment as a tool to guide and support undergraduate students in the practice of nursing. This method of learning and assessment promoted self- and peer evaluation as well as critical thinking. It encouraged students to take more responsibility for their learning and assisted academic staff and students to identify learning issues associated with clinical practices. Evaluative comments by teachers, students and educational experts have established the credibility and continued use of this approach within the Bachelor of Nursing program at a major university in Sydney, Australia.
|
|
|
| 2000 |
Finn T, King J, Thorburn J, 'The educational needs of part time clinical facilitators.', Contemporary Nurse A Journal for the Australian Nursing Profession, 9, 132-139 (2000)
Clinical facilitators play an important role in the clinical practicum component of an undergraduate nursing programme. Part time teachers are often employed in this ro... [more]
Clinical facilitators play an important role in the clinical practicum component of an undergraduate nursing programme. Part time teachers are often employed in this role, however very little has been written about the needs of these facilitators. An exploratory study design incorporating focus group interviews and questionnaires was used to identify the needs of clinical facilitators at a large Australian university. This study showed that they are committed nurses who often feel inadequate in a role they feel lacks support and identity. The findings of the study have implications for the preparation of clinical facilitators.
|
|
|
| 2000 |
Donaghue KC, Pena MM, Chan AKF, Blades BL, King J, Storlien LH, Silink M, 'Beneficial effects of increasing monounsaturated fat intake in adolescents with type 1 diabetes', DIABETES RESEARCH AND CLINICAL PRACTICE, 48, 193-199 (2000)
|
|
|
| 1999 |
Duffin AC, Donaghue KC, Potter M, McInnes A, Chan AKF, King J, Howard NJ, Silink M, 'Limited joint mobility in the hands and feet of adolescents with Type 1 diabetes mellitus', DIABETIC MEDICINE, 16, 125-130 (1999)
|
|
|
| 1997 |
Donoghue K, Fairchild J, Chan A, Hing S, King J, Howard NJ, Silink M, 'The prevalence of diabetes microvascular complications in prepubertal children', JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, 10, 579-585 (1997)
|
|
|
| 1997 |
Donaghue KC, Fairchild JM, Chan A, Hing SJ, King J, Howard NJ, Silink M, 'Diabetes microvascular complications in prepubertal children', JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, 10, 579-585
|
|
|
| 1997 |
Donaghue KC, Fung ATW, Hing S, Fairchild J, King J, Chan A, Howard NJ, Silink M, 'The effect of prepubertal diabetes duration on diabetes: Microvascular complications in early and late adolescence', DIABETES CARE, 20, 77-80 (1997)
|
|
|
| 1992 |
Colagiuri S, Bryson J, Keating S, Tan L, King J, Eigenmann C, Jørgensen KH, 'Conventional and Sprinkler Needle Injection of Magnesium Insulin', Diabetic Medicine, 9, 616-621 (1992)
Currently available short-acting insulin preparations fail to mimic the postprandial insulin profile of non-diabetic individuals. The activity of a novel insulin design... [more]
Currently available short-acting insulin preparations fail to mimic the postprandial insulin profile of non-diabetic individuals. The activity of a novel insulin designed for faster absorption has been tested after subcutaneous injection. Magnesium insulin (50 U ml-1) given by sprinkler needle was compared with unmodified human insulin (100 U ml-1) given by conventional needle and unmodified human insulin (50 U ml-1) given by sprinkler needle in normal volunteers using a euglycaemic clamp. Magnesium insulin had a significantly faster onset of action resulting in a higher exogenous insulin level by 15 min, peak level was reached after 60 min compared with 75 min for the unmodified insulins, and duration of action was significantly shorter than both unmodified insulins. No significant differences were observed between the unmodified insulins for the first 5 h after injection, indicating that the observed differences to magnesium insulin could not be attributed to the insulin concentration or the type of needle used for insulin administration. Injection of magnesium insulin prior to a test breakfast in people with Type 2 diabetes resulted in significantly lower total and 0 to 120 min areas under the glucose curve, an earlier rise in exogenous insulin levels and a higher area under the insulin curve from 0 to 120 min compared with unmodified 100 U ml-1 human insulin. 1992 Diabetes UK
|
|
|