Dr Lauren Schooth

Dr Lauren Schooth

Postdoctoral Researcher

School of Biomedical Sciences and Pharmacy

Career Summary

Biography

Dr Lauren Schooth is a postdoctoral researcher in Professor Simon Keely’s laboratory within the Immune Health Research Program at the University of Newcastle. A microbiologist by training, her research focuses on the complex interactions between the gastrointestinal microbiome, host immunity, and human health, with particular emphasis on inflammatory bowel disease (IBD) and disorders of gut–brain interaction.

Lauren’s work integrates advanced anaerobic microbial culture, metagenomics, and bioinformatic analysis to explore how microbial communities contribute to mucosal healing, immune homeostasis, and disease progression. She is currently leading investigations into stool microbial variation in active and remitted IBD, aiming to identify key taxa that may influence clinical outcomes.

Lauren completed her PhD in Microbiology at The University of Queensland, where she developed novel ex vivo methods combining microbial culture with metagenomic sequencing to characterise the mucosa‑associated microbiota in digestive health and disease. Her doctoral and postdoctoral research has produced numerous contributions to the field, including first‑author publications, industry-funded microbiome reports, and invited presentations at national conferences.

Her work has been recognised through multiple competitive awards and grants, including the Gastroenterological Society of Queensland Young Investigator Award (2024) and several Centre for Research Excellence in Digestive Health Pilot Grants.

In addition to her research, Lauren is deeply committed to teaching and mentorship. She has served as a lead laboratory demonstrator and tutor in microbiology, immunology, and molecular cell biology, and has supervised undergraduate research projects to high achievement.

Driven by a passion for translational science and microbial ecology, Lauren’s ongoing goal is to improve our understanding of host–microbe interactions and support the development of microbiome‑informed therapeutics for gastrointestinal disease.


Qualifications

  • DOCTOR OF PHILOSOPHY, University of Queensland
  • BACHELOR OF ADVANCED SCIENCE (HONOURS), University of Queensland

Keywords

  • DGBI
  • anaerobes
  • gastroenterology
  • gut microbiome
  • immunology
  • inflammatory bowel disease
  • microbiology

Languages

  • English (Mother)

Fields of Research

Code Description Percentage
310704 Microbial genetics 40
310701 Bacteriology 30
320402 Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies) 30

Professional Experience

UON Appointment

Title Organisation / Department
Casual Academic University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia
Postdoctoral Researcher University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia

Professional appointment

Dates Title Organisation / Department
1/7/2024 - 31/12/2024 Postdoctoral Researcher The University of Queensland
Faculty of Medicine
Australia

Awards

Award

Year Award
2024 Gastroenterological Society of Queensland Young Investigator Award
Gastroenterological Society of Queensland
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Conference (7 outputs)

Year Citation Altmetrics Link
2024 Schooth L, Burns G, Minahan K, Teh J-J, Fairlie T, Shah A, Holtmann G, Morrison M, 'The duodenal mucosa-associated microbiota differs in patients based on their Rome IV classification, and has variable effects on duodenal spheroid barrier function subjects', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 39, 264-265 (2024)
2024 Fairlie T, Shah A, Lim Y, Teh JJ, Schooth LF, Morrison M, Holtmann GJ, 'SIMETHICONE SUPPRESSES THE GROWTH OF MICROBES CULTURED FROM THE HUMAN DUODENAL MUCOSA', GASTROENTEROLOGY, 166, S866-S867 (2024)
2024 Fairlie T, Shah A, Lim Y, Teh J-J, Schooth L, Morrison M, Holtmann G, 'Simethicone suppresses the growth of microbes cultured from the human duodenal mucosa', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 39, 262-262 (2024)
2024 Schooth LF, Kang S, Fairlie T, Lim Y, Teh JJ, Hoedt EC, Keely S, Shah A, Holtmann GJ, Morrison M, 'THE DUODENAL MUCOSA-ASSOCIATED MICROBIOTA OF PATIENTS WITH A DISORDER OF GUT-BRAIN INTERACTION CAN BE DIFFERENTIATED BY ROME IV CRITERIA', GASTROENTEROLOGY, 166, S776-S776 (2024)
Co-authors Simon Keely, Emily Hoedt
2022 Schooth LF, Ahmed AS, Kang S, Shah A, Fairlie T, Teh JJ, Lim Y, Hoedt EC, Talley NJ, Keely S, Holtmann GJ, Morrison M, 'STRAIN-LEVEL FUNCTIONAL AND PHENOTYPIC RESOLUTION OF THE DUODENAL MUCOSA-ASSOCIATED MICROBIOTA IN FUNCTIONAL DYSPEPSIA AND HEALTHY CONTROL SUBJECTS VIA A NOVEL EX VIVO COMBINATION OF MICROBE CULTURE AND METAGENOMIC SEQUENCING', GASTROENTEROLOGY, 162, S509-S510 (2022)
Co-authors Simon Keely, Nicholas Talley, Emily Hoedt
2021 Teh JJ, Kang S, Schooth LF, Loayza JJJ, Zhang J, Zhang F, Liu Q, Hamilton AL, Wilson-O'Brien A, Ching JY, Sung JJ, Yu J, Ng SC, Kamm MA, Morrison M, 'NOVEL CHARACTERIZATION OF THE SECRETOMES OF CROHN'S DISEASE MUCOSA-ASSOCIATED MICROBIOTA, AND THEIR MODULATION OF INFLAMMATION THROUGH NF-¿B SIGNALLING. THE ENIGMA STUDY.', GASTROENTEROLOGY, 160, S538-S539 (2021)
2020 Schooth LF, Johana J, Loayza J, Teh JJ, Zhang J, Zhang F, Liu Q, Hamilton AL, Wilson-O'Brien A, Trakman GL, Lin WY, Ching JY, Sung JJ, Yu J, Ng SC, Kamm MA, Morrison M, 'CROHN'S DISEASE PATHOBIONT ENTEROBACTERIACEAE GROWTH IS MODULATED BY FOOD ADDITIVES AND OXYGEN AVAILABILITY: FACTORS IN PATHOPHYSIOLOGY AND RECURRENCE. THE ENIGMA STUDY.', GASTROENTEROLOGY, 158, S2-S2 (2020)
Citations Web of Science - 1
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Journal article (3 outputs)

Year Citation Altmetrics Link
2022 Schooth LF, Ahmed AS, Kang S, Shah A, Fairlie T, Teh JJ, Lim Y, Hoedt EC, Talley NJ, Keely S, Holtmann GJ, Morrison M, 'Su1119: STRAIN-LEVEL FUNCTIONAL AND PHENOTYPIC RESOLUTION OF THE DUODENAL MUCOSA-ASSOCIATED MICROBIOTA IN FUNCTIONAL DYSPEPSIA AND HEALTHY CONTROL SUBJECTS VIA A NOVEL EX VIVO COMBINATION OF MICROBE CULTURE AND METAGENOMIC SEQUENCING', Gastroenterology, 162 (2022)
DOI 10.1016/s0016-5085(22)61208-3
Co-authors Simon Keely, Nicholas Talley, Emily Hoedt
2021 Teh JJ, Kang S, Schooth LF, Loayza JJJ, Zhang J, Zhang F, Liu Q, Hamilton AL, Wilson-O'Brien A, Ching JY, Sung JJ, Yu J, Ng SC, Kamm MA, Morrison M, 'Sa533 NOVEL CHARACTERIZATION OF THE SECRETOMES OF CROHN'S DISEASE MUCOSA-ASSOCIATED MICROBIOTA, AND THEIR MODULATION OF INFLAMMATION THROUGH NF-¿B SIGNALLING. THE ENIGMA STUDY.', Gastroenterology, 160 (2021)
DOI 10.1016/s0016-5085(21)01989-2
2020 Schooth LF, Loayza JJJ, Teh JJ, Zhang J, Zhang F, Liu Q, Hamilton AL, Wilson-O'Brien A, Trakman GL, Lin WY, Ching JY, Sung JJ, Yu J, Ng SC, Kamm MA, Morrison M, '4 CROHN'S DISEASE PATHOBIONT ENTEROBACTERIACEAE GROWTH IS MODULATED BY FOOD ADDITIVES AND OXYGEN AVAILABILITY: FACTORS IN PATHOPHYSIOLOGY AND RECURRENCE. THE ENIGMA STUDY.', Gastroenterology, 158, s-2 (2020)
DOI 10.1016/s0016-5085(20)30685-5
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Dr Lauren Schooth

Positions

Postdoctoral Researcher
Keely Lab
School of Biomedical Sciences and Pharmacy
College of Health, Medicine and Wellbeing

Casual Academic
Keely Lab
School of Biomedical Sciences and Pharmacy
College of Health, Medicine and Wellbeing

Contact Details

Email lauren.schooth@newcastle.edu.au
Mobile 0403688448
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