Ms Rose Upton

Ms Rose Upton

Research student

Career Summary

Biography

Rose Upton is a Sessional Academic and a PhD Student in Conservation Biology in the School of Environmental and Life Sciences at the University of Newcastle. Her research is focused on the development of artificial reproductive technologies for amphibian populations in crisis. Her PhD focuses on the cryopreservation of sperm and IVF techniques, particularly in the endangered green and golden bell frog. Rose hopes her research can help reduce the dramatic decline of amphibians in Australia

Prior to commencing her PhD, Rose completed a Bachelor of Science (Honours Class I) at the University of Newcastle. Her work has been recognised by the university with the a Faculty of Science and IT Honours Faculty Medal. Rose has been awarded a full research scholarship by the University of Newcastle, and most recently was awarded a PhD Student Research Grant by the Australian Society of Herpetologists.


Keywords

  • amphibians
  • artificial reproductive technologies
  • conservation
  • cryopreservation
  • reproduction

Fields of Research

Code Description Percentage
050202 Conservation and Biodiversity 30
060899 Zoology not elsewhere classified 30
060803 Animal Developmental and Reproductive Biology 40

Awards

Honours

Year Award
2016 Bachelor of Science (Hons) Class I
Faculty of Science and Information Technology The University of Newcastle
2016 Faculty of Science and IT Medal
Faculty of Science and Information Technology The University of Newcastle

Prize

Year Award
2018 The MP Biomedicals award for best 3rd Year PhD Student Presentation
Faculty of Science and Information Technology The University of Newcastle

Teaching

Code Course Role Duration
ENVS2004 Ecology
Faculty of Science and Information Technology The University of Newcastle
Laboratory Demonstrator 1/09/2016 - 31/12/2019
ENVS2006 Australian Fauna
Faculty of Science and Information Technology The University of Newcastle
Demonstrator 1/04/2017 - 31/12/2019
BIOL1003 Biology Professional Skills I
Faculty of Science and Information Technology The University of Newcastle
Laboratory Demonstrator/Tutorial 1/07/2018 - 31/12/2018
0000 Experiment Fest (Biology)
Faculty of Science and Information Technology The University of Newcastle
Demonstrator 22/06/2018 - 29/06/2018
ENVS3002 Applied Environmental Science
Faculty of Science and Information Technology The University of Newcastle
Invited Speaker 1/09/2017 - 2/09/2017
ENVS3003 Conservation Biology
Faculty of Science and Information Technology The University of Newcastle
Demonstrator 1/02/2017 - 28/02/2019
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (1 outputs)

Year Citation Altmetrics Link
2019 Clulow J, Upton R, Trudeau VL, Clulow S, 'Amphibian Assisted Reproductive Technologies: Moving from Technology to Application.', 413-463 (2019)
DOI 10.1007/978-3-030-23633-5_14
Co-authors John Clulow, Simon Clulow

Journal article (9 outputs)

Year Citation Altmetrics Link
2019 Gould J, Valdez JW, Upton R, 'Adhesive defence mucus secretions in the red triangle slug (Triboniophorus graeffei) can incapacitate adult frogs', ETHOLOGY, 125 587-591 (2019) [C1]
DOI 10.1111/eth.12875
2019 Hayward MW, Scanlon RJ, Callen A, Howell LG, Klop-Toker KL, Di Blanco Y, et al., 'Reintroducing rewilding to restoration Rejecting the search for novelty', Biological Conservation, 233 255-259 (2019) [C1]

© 2019 Rewilding is emerging as a major issue in conservation. However, there are currently a dozen definitions of rewilding that include Pleistocene rewilding, island rewilding, ... [more]

© 2019 Rewilding is emerging as a major issue in conservation. However, there are currently a dozen definitions of rewilding that include Pleistocene rewilding, island rewilding, trophic rewilding, functional rewilding and passive rewilding, and these remain fuzzy, lack clarity and, hence, hinder scientific discourse. Based on current definitions, it is unclear how the interventions described under the rewilding umbrella differ from those framed within the long-standing term ¿restoration¿. Even projects held up as iconic rewilding endeavours invariably began as restoration projects (e.g., Oostvaaderplassen; Pleistocene Park; the return of wolves to Yellowstone, etc.). Similarly, rewilding organisations (e.g., Rewilding Europe) typically began with a restoration focus. Scientific discourse requires precise language. The fuzziness of existing definitions of rewilding and lack of distinction from restoration practices means that scientific messages cannot be transferred accurately to a policy or practice framework. We suggest that the utility of ¿rewilding¿ as a term is obsolete, and hence recommend scientists and practitioners use ¿restoration¿ instead.

DOI 10.1016/j.biocon.2019.03.011
Citations Scopus - 1
Co-authors Anita Chalmers, Andrea Griffin, John Rodger, Alex Callen, John Clulow, Matthew Hayward, Simon Clulow
2019 Hayward MW, Callen A, Allen BL, Ballard G, Broekhuis F, Bugir C, et al., 'Deconstructing compassionate conservation.', Conserv Biol, 33 760-768 (2019) [C1]
DOI 10.1111/cobi.13366
Co-authors John Clulow, Ryan Witt, Andrea Griffin, Simon Clulow, Alex Callen, Matthew Hayward
2019 Browne RK, Silla AJ, Upton R, Della-Togna G, Marcec-Greaves R, Shishova NV, et al., 'Sperm collection and storage for the sustainable management of amphibian biodiversity', Theriogenology, 133 187-200 (2019) [C1]
DOI 10.1016/j.theriogenology.2019.03.035
Citations Scopus - 1Web of Science - 1
Co-authors Simon Clulow, John Clulow
2018 Upton R, Clulow S, Mahony MJ, Clulow J, 'Generation of a sexually mature individual of the Eastern dwarf tree frog, Litoria fallax, from cryopreserved testicular macerates: proof of capacity of cryopreserved sperm derived offspring to complete development', CONSERVATION PHYSIOLOGY, 6 (2018) [C1]
DOI 10.1093/conphys/coy043
Citations Scopus - 1Web of Science - 1
Co-authors John Clulow, Simon Clulow
2018 Hall SE, Upton RMO, McLaughlin EA, Sutherland JM, 'Phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) and Janus kinase/signal transducer and activator of transcription (JAK/STAT) follicular signalling is conserved in the mare ovary', Reproduction, Fertility and Development, 30 624-633 (2018) [C1]

© CSIRO 2018. The mare ovary is unique in its anatomical structure; however, the signalling pathways responsible for physiological processes, such as follicular activation, remain... [more]

© CSIRO 2018. The mare ovary is unique in its anatomical structure; however, the signalling pathways responsible for physiological processes, such as follicular activation, remain uncharacterised. This provided us with the impetus to explore whether signalling molecules from important folliculogenesis pathways, phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) and Janus kinase/signal transducer and activator of transcription (JAK/STAT), are conserved in the mare ovary. Messenger RNA expression of six genes important in follicle development was measured using quantitative polymerase chain reaction and protein localisation of key pathway members (PI3K, AKT1, phosphatase and tensin homologue (PTEN), JAK1, STAT3 and suppressor of cytokine signalling 4 (SOCS4)) was compared in tissue from fetal and adult mare ovaries. Tissue from adult ovaries exhibited significantly increased levels of mRNA expression of PI3K, AKT1, PTEN, JAK1, STAT3 and SOCS4 compared with tissue from fetal ovaries. PI3K, AKT1, JAK1 and STAT3 demonstrated redistributed localisation, from pregranulosa cells in fetal development, to both the oocyte and granulosa cells of follicles in the adult ovary, whilst negative feedback molecules PTEN and SOCS4 were only localised to the granulosa cells in the adult ovary. These findings suggest that the PI3K/AKT and JAK/STAT signalling pathways are utilised during folliculogenesis in the mare, similarly to previously studied mammalian species, and may serve as useful biomarkers for assessment of ovary development in the horse.

DOI 10.1071/RD17024
Citations Scopus - 5Web of Science - 5
Co-authors Jessie Sutherland, Eileen Mclaughlin
2018 Clulow J, Pomering M, Herbert D, Upton R, Calatayud N, Clulow S, et al., 'Differential success in obtaining gametes between male and female Australian temperate frogs by hormonal induction: A review', GENERAL AND COMPARATIVE ENDOCRINOLOGY, 265 141-148 (2018) [C1]
DOI 10.1016/j.ygcen.2018.05.032
Citations Scopus - 3Web of Science - 5
Co-authors Simon Clulow, John Clulow
2018 Upton R, Clulow S, Seeto R, Wong L, Mahony M, Clulow J, 'Successful sperm cryopreservation and generated offspring of the endangered frog, Litoria aurea', Cryobiology, 85 148-149 (2018)
DOI 10.1016/j.cryobiol.2018.10.114
2018 Campbell L, Upton R, Doody SJ, Nixon B, Clulow J, Clulow S, 'Model protocol for cryopreservation of lizard sperm using the phosphodiesterase inhibitor caffeine', Cryobiology, 85 150-150 (2018)
DOI 10.1016/j.cryobiol.2018.10.120
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Conference (1 outputs)

Year Citation Altmetrics Link
2018 Upton R, Clulow S, Seeto R, Wong L, Mahony M, Clulow J, '55th Annual Meeting for the Society for Cryobiology', Successful sperm cryopreservation and generated offspring of the endangered frog, Litoria aurea, Madrid (2018)
Co-authors Simon Clulow, John Clulow
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Grants and Funding

Summary

Number of grants 1
Total funding $2,000

Click on a grant title below to expand the full details for that specific grant.


20191 grants / $2,000

The Australian Society of Herpetologists PhD Research Grant$2,000

Funding body: The Australian Socirty of Herpetologists

Funding body The Australian Socirty of Herpetologists
Scheme Student Research Grant (PhD)
Role Lead
Funding Start 2019
Funding Finish 2019
GNo
Type Of Funding External
Category EXTE
UON N
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Ms Rose Upton

Contact Details

Email rose.upton@uon.edu.au
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