Dr Luchun Duan

Dr Luchun Duan

Research Fellow

Global Centre for Environmental Remediation

Career Summary

Biography

Dr Duan has been working in the field of risk assessment of environmental contaminants for more than 6 years. Her PhD study focused on organic contaminants, specifically polycyclic aromatic hydrocarbons (PAHs) in soils. She is continuing work with CRC CARE within the project minimizing uncertainty of human health risk assessment.  Within this project she leads organic contaminants bioavailability. She is also China Program Coordinator for CRC CARE, and in this role facilitates collaboration with Chinese partners.

Expertise

  • Long-term risk assessment of PAHs contaminated soils and relevant policy;
  • Standard operation procedure for both in vivo and in vitro bioavailability/bioaccessibility tests;
  • Risk-based novel remediation strategy based on reduce bioavailability.

 

Current and future projects

  • Primary researcher in the CRC CARE project: minimising uncertainties of human health risk assessment
    • Establish standard operating procedure (SOP) for bioavailability/bioaccessbility methods
    • Remediation strategy
    • Improve risk-based management policy
  • Ecological risk assessment of PAHs
  • Ecological risk assessment and human health risk assessment of perfluorinated chemicals (PFCs) in soil and water

Qualifications

  • PhD, University of South Australia

Keywords

  • contaminant land management (policy)
  • contaminants' bioavailability (organics)
  • human health risk assessment
  • soil science

Languages

  • Mandarin (Mother)
  • English (Fluent)

Fields of Research

Code Description Percentage
050299 Environmental Science and Management not elsewhere classified 50
100701 Environmental Nanotechnology 20
050204 Environmental Impact Assessment 30

Professional Experience

UON Appointment

Title Organisation / Department
Research Fellow University of Newcastle
Global Centre for Environmental Remediation
Australia
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Journal article (15 outputs)

Year Citation Altmetrics Link
2018 Yu L, Duan L, Naidu R, Semple KT, 'Abiotic factors controlling bioavailability and bioaccessibility of polycyclic aromatic hydrocarbons in soil: Putting together a bigger picture', Science of the Total Environment, 613-614 1140-1153 (2018) [C1]

© 2017 Elsevier B.V. The bioavailability and bioaccessibility of polycyclic aromatic hydrocarbons (PAHs) in soil underpin the risk assessment of contaminated land with these cont... [more]

© 2017 Elsevier B.V. The bioavailability and bioaccessibility of polycyclic aromatic hydrocarbons (PAHs) in soil underpin the risk assessment of contaminated land with these contaminants. Despite a significant volume of research conducted in the past few decades, comprehensive understanding of the factors controlling the behaviour of soil PAHs and a set of descriptive soil parameters to explain variations in PAH bioavailability and bioaccessibility are still lacking. This review focuses on the role of source materials on bioavailability and bioaccessibility of soil PAHs, which is often overlooked, along with other abiotic factors including contaminant concentration and mixture, soil composition and properties, as well as environmental factors. It also takes into consideration the implications of different types of risk assessment (ecological and human health) on bioavailability and bioaccessibility of PAHs in soil. We recommend that future research should (1) account for the effects of source materials on bioavailability and bioaccessibility of soil PAHs; (2) adopt non-disruptive methods to analyse soil components controlling PAH sequestration; (3) integrate both natural organic matter (NOM) and xenobiotic organic matter (XOM) while evaluating the influences of soil organic matter (SOM) on the behaviour of PAHs; and (4) consider the dissimilar desorption scenarios in ecological risk assessment and human health risk assessment while assessing PAH bioavailability and bioaccessibility.

DOI 10.1016/j.scitotenv.2017.09.025
Citations Scopus - 1Web of Science - 1
Co-authors Ravi Naidu
2017 Qi F, Naidu R, Bolan NS, Dong Z, Yan Y, Lamb D, et al., 'Pyrogenic carbon in Australian soils', SCIENCE OF THE TOTAL ENVIRONMENT, 586 849-857 (2017) [C1]
DOI 10.1016/j.scitotenv.2017.02.064
Citations Scopus - 3Web of Science - 3
Co-authors Nanthi Bolan, Morrow Dong, Dane Lamb, Ravi Naidu
2017 Dong Z, Bahar MM, Jit J, Kennedy B, Priestly B, Ng J, et al., 'Issues raised by the reference doses for perfluorooctane sulfonate and perfluorooctanoic acid', ENVIRONMENT INTERNATIONAL, 105 86-94 (2017) [C1]
DOI 10.1016/j.envint.2017.05.006
Co-authors Mezbaul Bahar, Dane Lamb, Ravi Naidu, Morrow Dong, Yanju Liu
2017 Umeh AC, Duan L, Naidu R, Semple KT, 'Residual hydrophobic organic contaminants in soil: Are they a barrier to risk-based approaches for managing contaminated land?', ENVIRONMENT INTERNATIONAL, 98 18-34 (2017) [C1]
DOI 10.1016/j.envint.2016.09.025
Citations Scopus - 5Web of Science - 4
Co-authors Anthony Umeh Uon, Ravi Naidu
2017 Islam S, Rahman MM, Duan L, Islam MR, Kuchel T, Naidu R, 'Variation in arsenic bioavailability in rice genotypes using swine model: An animal study', SCIENCE OF THE TOTAL ENVIRONMENT, 599 324-331 (2017) [C1]
DOI 10.1016/j.scitotenv.2017.04.215
Co-authors Mahmud Rahman, Ravi Naidu
2016 Dong Z, Yan K, Liu Y, Naidu R, Duan L, Wijayawardena A, et al., 'A meta-analysis to correlate lead bioavailability and bioaccessibility and predict lead bioavailability', Environment International, 92-93 139-145 (2016) [C1]
DOI 10.1016/j.envint.2016.04.009
Citations Scopus - 1Web of Science - 1
Co-authors Ayanka Wijayawardena, Mahmud Rahman, Ravi Naidu, Morrow Dong, Yanju Liu
2016 Duan L, Naidu R, Liu Y, Dong Z, Mallavarapu M, Herde P, et al., 'Comparison of oral bioavailability of benzo[a]pyrene in soils using rat and swine and the implications for human health risk assessment', Environment International, 94 95-102 (2016) [C1]

© 2016 Elsevier Ltd. Background: There are many uncertainties concerning variations in benzo[a]pyrene (B[a] P) soil guidelines protecting human health based on carcinogenic data ... [more]

© 2016 Elsevier Ltd. Background: There are many uncertainties concerning variations in benzo[a]pyrene (B[a] P) soil guidelines protecting human health based on carcinogenic data obtained in animal studies. Although swine is recognised as being much more representative of the human child in terms of body size, gut physiology and genetic profile the rat/mice model is commonly used in practice. Objectives: We compare B[a]P bioavailability using a rat model to that estimated in a swine model, to investigate the correlation between these two animal models. This may help reduce uncertainty in applying bioavailability to human health risk assessment. Methods: Twelve spiked soil samples and a spiked silica sand (reference material) were dosed to rats in parallel with a swine study. B[a] P bioavailability was estimated by the area under the plasma B[a]P concentration-time curve (AUC) and faecal excretion as well in the rats. Direct comparison between the two animal models was made for: firstly, relative bioavailability (RB) using AUC assay; and secondly, the two assays in the rat model. Results: Both AUC and faecal excretion assays showed linear dose-response for the reference material. However, absolute bioavailability was significantly higher when using faecal excretion assay (p < 0.001). In aged soils faecal excretion estimated based on solvent extraction was not accurate due to the form of non-extractable fraction through ageing. A significant correlation existed between the two models using RB for soil samples (RB rat = 0.26RB swine + 17.3, R 2 = 0.70, p < 0.001), despite the regression slope coefficient revealing that the rat model would underestimate RB by about one quarter compared to using swine. Conclusions: In the comparison employed in this study, an interspecies difference of four in RB using AUC assay was identified between the rat and swine models regarding pharmacokinetic differences, which supported the body weight scaling method recommended by US EPA. Future research should focus on the carcinogenic competency (pharmacodynamics) used in experiment animals and humans.

DOI 10.1016/j.envint.2016.04.041
Citations Scopus - 3Web of Science - 3
Co-authors Ravi Naidu, Yanju Liu, Morrow Dong, Megh Mallavarapu
2016 Yu L, Vázquez-Cuevas G, Duan L, Semple KT, 'Buffered cyclodextrin extraction of -phenanthrene from black carbon amended soil', Environmental Technology & Innovation, 6 177-184 (2016) [C1]
DOI 10.1016/j.eti.2016.09.002
Citations Scopus - 1
2015 Duan L, Naidu R, Liu Y, Palanisami T, Dong Z, Mallavarapu M, Semple KT, 'Effect of ageing on benzo[a]pyrene extractability in contrasting soils', Journal of Hazardous Materials, 296 175-184 (2015) [C1]
DOI 10.1016/j.jhazmat.2015.04.050
Citations Scopus - 12Web of Science - 11
Co-authors Thava Palanisami, Yanju Liu, Morrow Dong, Ravi Naidu, Megh Mallavarapu
2015 Duan L, Naidu R, Thavamani P, Meaklim J, Megharaj M, 'Managing long-term polycyclic aromatic hydrocarbon contaminated soils: a risk-based approach', Environmental Science and Pollution Research, 22 8927-8941 (2015)
DOI 10.1007/s11356-013-2270-0
Citations Scopus - 14Web of Science - 9
Co-authors Ravi Naidu, Thava Palanisami, Megh Mallavarapu
2015 Zheng X, Han B, Thavamani P, Duan L, Naidu R, 'Composition, source identification and ecological risk assessment of polycyclic aromatic hydrocarbons in surface sediments of the Subei Grand Canal, China', ENVIRONMENTAL EARTH SCIENCES, 74 2669-2677 (2015)
DOI 10.1007/s12665-015-4287-9
Citations Scopus - 5Web of Science - 5
Co-authors Thava Palanisami, Ravi Naidu
2015 Dong Z, Liu Y, Duan L, Bekele D, Naidu R, 'Uncertainties in human health risk assessment of environmental contaminants: A review and perspective', Environment International, 85 120-132 (2015) [C1]

© 2015 Elsevier Ltd. Addressing uncertainties in human health risk assessment is a critical issue when evaluating the effects of contaminants on public health. A range of uncerta... [more]

© 2015 Elsevier Ltd. Addressing uncertainties in human health risk assessment is a critical issue when evaluating the effects of contaminants on public health. A range of uncertainties exist through the source-to-outcome continuum, including exposure assessment, hazard and risk characterisation. While various strategies have been applied to characterising uncertainty, classical approaches largely rely on how to maximise the available resources. Expert judgement, defaults and tools for characterising quantitative uncertainty attempt to fill the gap between data and regulation requirements. The experiences of researching 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) illustrated uncertainty sources and how to maximise available information to determine uncertainties, and thereby provide an 'adequate' protection to contaminant exposure. As regulatory requirements and recurring issues increase, the assessment of complex scenarios involving a large number of chemicals requires more sophisticated tools. Recent advances in exposure and toxicology science provide a large data set for environmental contaminants and public health. In particular, biomonitoring information, in vitro data streams and computational toxicology are the crucial factors in the NexGen risk assessment, as well as uncertainties minimisation. Although in this review we cannot yet predict how the exposure science and modern toxicology will develop in the long-term, current techniques from emerging science can be integrated to improve decision-making.

DOI 10.1016/j.envint.2015.09.008
Citations Scopus - 9Web of Science - 9
Co-authors Ravi Naidu, Yanju Liu, Dawit Bekele, Morrow Dong
2014 Duan L, Palanisami T, Liu Y, Dong Z, Mallavarapu M, Kuchel T, et al., 'Effects of ageing and soil properties on the oral bioavailability of benzo[a]pyrene using a swine model', Environment International, 70 192-202 (2014) [C1]
DOI 10.1016/j.envint.2014.05.017
Citations Scopus - 25Web of Science - 24
Co-authors Ravi Naidu, Morrow Dong, Yanju Liu, Thava Palanisami, Megh Mallavarapu
2013 Duan L, Naidu R, 'Effect of Ionic Strength and Index Cation on the Sorption of Phenanthrene', WATER AIR AND SOIL POLLUTION, 224 (2013)
DOI 10.1007/s11270-013-1700-4
Citations Scopus - 7Web of Science - 8
Co-authors Ravi Naidu
2013 Duan L, Naidu R, 'Effect of ionic strength and index cation on the sorption of phenanthrene topical collection on remediation of site contamination', Water, Air, and Soil Pollution, 224 (2013)

Sorption characteristics of phenanthrene were studied in batch equilibrium experiments with 32 Australian soils that varied widely in physicochemical properties. Sorption of phena... [more]

Sorption characteristics of phenanthrene were studied in batch equilibrium experiments with 32 Australian soils that varied widely in physicochemical properties. Sorption of phenanthrene varied widely among the soils and was generally nonlinear, with the nonlinearity index (n) of the Freundlich isotherm varying from 0.62 to 1.01. Simple regression analyses revealed that total organic carbon (TOC) accounts for about 68 % of the variation in the partition coefficient (K' f ) for sorption among the soils at an equilibrium concentration (C e ) of 0.05 mg/L. The organic carbon normalized distribution coefficient (K OC ), varied considerably between soils with > 70 % of the variance of logK OC being accounted for by logTOC, clay and log dissolved organic carbon (DOC). These results show that the phenanthrene C e is influenced by both TOC as well as the DOC in soil suspensions. The effects of ionic strength (IS) and index cation were investigated using four contrasting soils. Results show that with an increase in IS from 0.03 to 0.15 M sorption of phenanthrene generally increased in CaCl 2 background solutions, whereas the effect was less significant and variable in NaCl background solutions. Sorption of phenanthrene was slightly higher at low IS (0.03 M) with Na + as index cation compared with that of Ca 2+ , whereas an opposite trend was observed at higher IS (0.15 M). For two soils high in TOC, the flocculation of endogenous DOC in the presence of Ca 2+ reduced the influence of background electrolyte and resulted in a more linear sorption isotherm as well as higher sorption capacity. This trend was more significant with Ca 2+ relative to Na + . © 2013 Springer Science+Business Media Dordrecht.

DOI 10.1007/s11270-013-1700-4
Citations Scopus - 5
Co-authors Ravi Naidu
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Grants and Funding

Summary

Number of grants 2
Total funding $4,540,918

Click on a grant title below to expand the full details for that specific grant.


20171 grants / $860,918

A fully integrated risk assessment system$860,918

Funding body: CRC CARE Pty Ltd

Funding body CRC CARE Pty Ltd
Project Team Doctor Yanju Liu, Doctor Luchun Duan, Doctor Ayanka Wijayawardena, Doctor Morrow Dong, Professor Ravi Naidu
Scheme Research Project
Role Investigator
Funding Start 2017
Funding Finish 2018
GNo G1700897
Type Of Funding CRC - Cooperative Research Centre
Category 4CRC
UON Y

20131 grants / $3,680,000

Minimising Uncertainty in Human Health Risk Assessment Using a Compliance Model$3,680,000

This will provide scientific basis for risk characterisation and much needed confidence to assessors, decision-makers, and the public, and thus selecting an optimal environmental management strategy.

Funding body: CRC CARE Pty Ltd

Funding body CRC CARE Pty Ltd
Project Team

Project leader: Prof Ravi Naidu; Researchers: Dr Morrow Dong, Dr Ayanka Nanayakkara, Dr Luchun Duan; Collaborator: Prof Kirk Semple, Prof Jack Ng

Scheme Research Project
Role Investigator
Funding Start 2013
Funding Finish 2018
GNo
Type Of Funding CRC - Cooperative Research Centre
Category 4CRC
UON N
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Research Supervision

Number of supervisions

Completed0
Current3

Total current UON EFTSL

PhD1.1

Current Supervision

Commenced Level of Study Research Title Program Supervisor Type
2017 PhD Study on Occurrence and Distribution of Antibiotic Residues/ Pesticides/Nutrients in Drinking Water and Agriculture Aquatic Environment by Passive Sampling Method PhD (Environment Remediation), Faculty of Science, The University of Newcastle Principal Supervisor
2015 PhD Bioavailability, Risk Assessment and Remediation of Soil Organic Contaminants PhD (Environment Remediation), Faculty of Science, The University of Newcastle Co-Supervisor
2015 PhD Bioaccessibility, Risk Assessment and Remediation of Contaminated Land PhD (Environment Remediation), Faculty of Science, The University of Newcastle Co-Supervisor
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Dr Luchun Duan

Position

Research Fellow
Global Centre for Environmental Remediation
Global Centre for Environmental Remediation
Faculty of Science

Contact Details

Email luchun.duan@newcastle.edu.au

Office

Room ATC
Building Advanced Technology Centre.
Location Callaghan
University Drive
Callaghan, NSW 2308
Australia
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