Ms Linda Truong

Ms Linda Truong

Research student

Career Summary

Biography

Research Profile

Linda Truong is an Australian neuropharmacologist and research neurology clinical trials specialist in academia, public health hospitals, and global industry, attesting to the quality of her research ideas and the ability to prosecute international clinical trials over the past two decades. Linda was appointed clinical trial manager (2016), clinical trials researcher (2020), and then senior clinical trial manager (2022), at NSW Health and a NHMRC Centre for Research Excellence (CRE), and now Executive Director (Strategic Partnerships) at HAIKDA Research (2023). Linda has successfully collaborated extensively with both Australian and international clinical researchers and industry partners, addressing critical scientific inquiries related to clinical trial design, cannabis-based therapies, neurological disorders such as epilepsy, and innovative methodologies for co-designing clinical trials in neurodegenerative diseases alongside patient and consumer groups. As a national leader in clinical trials, her research has directly influenced clinical practice by providing the evidence base to understand the use of new epilepsy medications in four large paediatric hospitals in NSW, clarifying the safety and efficacy data of the new drug on seizures and facilitating the approval of new medicines for approval by the Therapeutic Goods Administration (TGA).

Linda has brought together and worked with clinical leaders, senior neuroscientists, clinical pharmacologists, and NSW health allied health professionals and developed the resources/infrastructure needed to address fundamental questions of importance to a group of epilepsy disorders of major health significance. These have revealed details of prescribing guidelines, transition pathways, new models of care, and informed clinical trial method modelling for therapeutic development and drug delivery for rare diseases. To facilitate further research discovery, Linda has made these resources and knowledge available to Australian researchers for further transformative research studies in her role on independent ethics, scientific and data monitoring committees (2018).

Research Grants

Linda has been awarded a ~$800,000 research grant and scholarship to support her research in Newcastle, Australia, and is one of the principal investigators on a research project to co-design new methodologies for the design of clinical trials with the participation of rare disease patient consumer groups. In clinical trials, registered drugs are tested in children and adults in NSW and have formed the basis for the first patient-centred clinical trial for epilepsy, with recent work targeting cannabis-based medicines. 

Research Interest

Linda serves as a passionate advocate for neurological spinal cord injury (2019) and works with numerous patient consumer groups for rare disease to incorporate the patient voice in the promotion of national patient-centred clinical trials for rare epilepsy, awareness of epilepsy, and improved symptomatology with new repurposed drugs.  She leads a large research team that uses clinical, patient-derived, and clinical methodologies to advance knowledge of epilepsy and clinical trials operations. Her vision is to continue to develop significant research capacity in rare epilepsy diseases on both seizure and non-seizure symptoms, and to coalesce Australian clinical research and patient capacity in these areas so that significant medical advances can be made with drug reimbursements for improved patient access.

Qualifications

Linda recently completed the Harvard Medical School Pharmacology: Clinical Drug Development and Discovery program, graduating within the top 10% of the cohort. This advanced training provided a comprehensive grounding in the scientific, regulatory, and translational aspects of modern drug development, encompassing preclinical pharmacology, clinical trial methodology, regulatory science, and emerging therapeutic modalities. Her performance in the program reflects a strong command of contemporary pharmacological principles and their application to rigorous, patient-centred clinical trials and research.


Keywords

  • Clinical Trials
  • Epilepsy
  • Neurology
  • Pharmacology

Languages

  • English (Fluent)
  • Vietnamese (Mother)

Fields of Research

Code Description Percentage
320905 Neurology and neuromuscular diseases 50
321402 Clinical pharmacology and therapeutics 50

Professional Experience

Membership

Dates Title Organisation / Department
7/9/2015 - 31/12/2015 NHMRC observer (Clinical Trials) NHMRC (National Health & Medical Research Council)
Australia

Professional appointment

Dates Title Organisation / Department
1/5/2024 -  Senior Clinical Trial Manager Hunter New England Local Health District
Australia
12/5/2022 -  Executive Director (Strategic Partnerships) HAIKDA research
Australia
12/5/2022 -  Academic Researcher - Clinical Trials School of Medicine and Public Health | University of Newcastle
Australia
15/9/2016 - 12/5/2022 Neurology Clinical Trials Project Manager Sydney Childrens Hospital, Randwick
Australia
10/3/2014 - 19/12/2014 Clinical Research Associate Five Corners | Now Avania
Australia
3/3/2014 - 15/9/2016 Research Development Officer - Medicines and Health University of Western Sydney
Australia
17/9/2012 - 30/9/2014 Clinical Trials Manager Assistant ICON Clinical Research (ICON Plc)
Australia
1/3/2010 - 17/9/2012 Neurology Clinical Trials Coordinator Prince of Wales Hospital
Australia
7/1/2002 - 31/1/2004 Pharmacologist - animal studies The University of Sydney
Australia

Teaching appointment

Dates Title Organisation / Department
5/1/2004 - 1/3/2010 Pharmacologist - Clinical trials The University of Sydney
Australia

Awards

Nomination

Year Award
2023 SWS STEM finalist award
Western Sydney Women

Prize

Year Award
2013 ICON Employee of the year
ICON Plc

Research Award

Year Award
2006 Young Research Investigators Award
The University of Sydney
2005 Reg Waite Award (Research). Silver medalist
Reg Waite Award Foundation
2004 Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) Travel Award
Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists

Invitations

Committee Member

Year Title / Rationale
2019 HREC Member

Panel Participant

Year Title / Rationale
2024 ASCEPT
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Conference (3 outputs)

Year Citation Altmetrics Link
2011 Lambert GA, Truong L, Zagami AS, 'The Effects of Somatostatin 2 Receptor Agonists and Antagonists on a Putative Migraine Trigger Pathway', HEADACHE, 51, 58-58 (2011)
2007 Truong L, Allbutt H, Coster M, Kassiou M, Henderson J, 'Efficacy of the NMDA antagonist (BZAD-01) in a rat model of Parkinson's disease (PD): Lesions to the thalamus', PARKINSONISM & RELATED DISORDERS, 13, S130-S130 (2007)
DOI 10.1016/S1353-8020(08)70732-6
2006 Truong L, Allbutt HN, Kassiou M, Henderson JM, 'Developing a preclinical model of Parkinson's disease: A study in rats with graded 6-OHDA lesions', MOVEMENT DISORDERS, 21, S76-S76 (2006)

Journal article (11 outputs)

Year Citation Altmetrics Link
2026 Truong L, Stettaford T, Watt K, Ghafournia N, Anetko P, Shin J, Pierce K, Lawson JA, Martin JH, 'PAtient-Centric epilepsy clinical trIal model For Improved health outcomes using Cannabidiol (PACIFIC study)—a methodology for developing patient-centred clinical trials in rare epilepsy syndromes', BMC Medical Research Methodology, 26 (2026) [C1]
DOI 10.1186/s12874-025-02757-1
Co-authors Nafi Ghafournia, Jenniferh Martin
2022 Hallinan CM, Eden E, Graham M, Greenwood L-M, Mills J, Popat A, Truong L, Bonomo Y, 'Over the counter low-dose cannabidiol: A viewpoint from the ACRE Capacity Building Group', JOURNAL OF PSYCHOPHARMACOLOGY, 36, 661-665 (2022) [C1]
DOI 10.1177/02698811211035394
Citations Scopus - 7Web of Science - 6
Co-authors Myfanwy Graham
2022 Hurley EN, Ellaway CJ, Johnson AM, Truong L, Gordon R, Galettis P, Martin JH, Lawson JA, 'Efficacy and safety of cannabidivarin treatment of epilepsy in girls with Rett syndrome: A phase 1 clinical trial', EPILEPSIA, 63, 1736-1747 (2022) [C1]
DOI 10.1111/epi.17247
Citations Scopus - 3Web of Science - 14
Co-authors Jenniferh Martin
2020 Zaidi K-B, Rich JB, Sunderland KM, Binns MA, Truong L, McLaughlin PM, Pugh B, Kwan D, Beaton D, Levine B, Sahlas DJ, Dowlatshahi D, Hassan A, Mandzia J, Troyer AK, Swartz RH, 'Methods for Improving Screening for Vascular Cognitive Impairment Using the Montreal Cognitive Assessment', CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 47, 756-763 (2020) [C1]
DOI 10.1017/cjn.2020.121
Citations Web of Science - 7
2018 Chen K-A, Farrar M, Cardamone M, Gill D, Smith R, Cowell CT, Truong L, Lawson JA, 'Cannabidiol for treating drug-resistant epilepsy in children: the New South Wales experience', MEDICAL JOURNAL OF AUSTRALIA, 209, 217-221 (2018) [C1]
DOI 10.5694/mja18.00023
Citations Scopus - 3Web of Science - 28
2014 Lambert GA, Hoskin KL, Michalicek J, Panahi SE, Truong L, Zagami AS, 'Stimulation of dural vessels excites the SI somatosensory cortex of the cat via a relay in the thalamus', CEPHALALGIA, 34, 243-257 (2014)
DOI 10.1177/0333102413508239
Citations Scopus - 9Web of Science - 5
2012 Yang L, Truong L, Fuss S, Bislimovic S, 'The effects of ageing and divided attention on the self-reference effect in emotional memory: Spontaneous or effortful mnemonic benefits?', MEMORY, 20, 596-607 (2012)
DOI 10.1080/09658211.2012.690040
Citations Web of Science - 25
2011 Lambert GA, Truong L, Zagami AS, 'Effect of cortical spreading depression on basal and evoked traffic in the trigeminovascular sensory system', CEPHALALGIA, 31, 1439-1451 (2011)
DOI 10.1177/0333102411422383
Citations Scopus - 7Web of Science - 56
2009 Truong L, Allbutt HN, Coster MJ, Kassiou M, Henderson JM, 'Behavioural effects of a selective NMDA NR1A/2B receptor antagonist in rats with unilateral 6-OHDA + parafascicular lesions', BRAIN RESEARCH BULLETIN, 78, 91-96 (2009)
DOI 10.1016/j.brainresbull.2008.10.004
Citations Scopus - 1Web of Science - 12
2009 Truong L, Brooks D, Amaral F, Henderson JM, Halliday GM, 'Relative Preservation of Thalamic Centromedian Nucleus in Parkinsonian Patients with Dystonia', MOVEMENT DISORDERS, 24, 2128-2135 (2009)
DOI 10.1002/mds.22747
Citations Scopus - 1Web of Science - 12
2006 Truong L, Allbutt H, Kassiou M, Henderson JM, 'Developing a preclinical model of Parkinson's disease: A study of behaviour in rats with graded 6-OHDA lesions', BEHAVIOURAL BRAIN RESEARCH, 169, 1-9 (2006)
DOI 10.1016/j.bbr.2005.11.026
Citations Scopus - 1Web of Science - 107
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Grants and Funding

Summary

Number of grants 2
Total funding $769,000

Click on a grant title below to expand the full details for that specific grant.


20241 grants / $14,000

Supplement Grant$14,000

Supplement grant supporting clinical trials co-design

Funding body: Philanthropy

Funding body Philanthropy
Project Team

Linda Truong

Scheme Philanthropy
Role Lead
Funding Start 2024
Funding Finish 2026
GNo
Type Of Funding C3300 – Aust Philanthropy
Category 3300
UON N

20231 grants / $755,000

Investigator Initiated Research Grant$755,000

Grant to support epilepsy research and new clinical trial design.

Funding body: Jazz Pharmaceuticals

Funding body Jazz Pharmaceuticals
Project Team

Linda Truong, Jennifer Martin, John Lawson

Scheme Jazz Pharmaceuticals
Role Lead
Funding Start 2023
Funding Finish 2027
GNo
Type Of Funding External
Category EXTE
UON N
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Research Projects

PACIFIC study 2022 - 2023


BEYOND clinical trial 2023 -

Collaborators

Name Organisation
John Lawson NSW Ministry of Health

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