Dr Frances Neville

Dr Frances Neville

Conjoint Lecturer

School of Environmental and Life Sciences (Chemistry)

Career Summary

Biography

Dr Frances Neville is currently a Conjoint Lecturer and Casual Academic at the School of Environmental and Life Sciences at the University of Newcastle, Australia. She is also a Casual Research Associate. She has previously worked as a University Research Fellow within the Faculty of Science and as a Research Associate in Chemistry and Chemical Engineering, also at Newcastle. Prior to this she carried out postdoctoral research at the University of Leeds, UK where she obtained her PhD. She works in the fields of physical and materials chemistry, and chemical engineering.

Research Expertise
I am a scientist with a broad chemistry experience, mainly in physical and materials chemistry. Most of my research involves synthesizing and characterizing functional inorganic/organic composite particles such as particles made of silica, polymers and magnetic cores, or mesoporous particles. The applications of the particles currently under investigation range from water purification to catalysis.  However, my research experience demonstrates considerable breadth evidenced by my work in surface chemistry as well as in electrochemistry, nanotechnology, physical chemistry and protein biochemistry.

My PhD studies were carried out at the Institute for Materials Research, University of Leeds, UK, using a range of material and surface science techniques including X-ray scattering (reflectivity and grazing incidence X-ray diffraction), as well as Langmuir trough measurements and electrochemistry (circular voltammetry, conductance and impedance spectroscopy). My first postdoctoral position was at the Institute for Membrane and Systems Biology,University of Leeds, UK, where I was sponsored by competitive European Commission (EC) funding under the Nanotechnology theme of the Framework 6 program.

Teaching Expertise

I am currently teaching the Environmental Chemistry Course (CHEM2610). I am the course coordinator as well as being a lecturer, tutor and demonstrator for the course.
Previously I was a head demonstrator for Introductory Chemistry (CHEM 1010 and CHEM1020, 2014-2015). I also taught Chemical Instrumental Analysis (CHEM3110) for four years (2011-2014) giving lectures and tutorials and also acting as a sole demonstrator for the whole of semester 1. I have previously taught Applied Chemistry (CHEM2510) and Pharmaceutical Chemistry (PHAR6114) at the University of Newcastle, giving lectures and tutorials. I have also carried out course development for several laboratory classes currently in use in CHEM3410 and CHEM3580.

Administrative Expertise
I am currently a peer-reviewer for:

  • American Chemical Society
    • ACS Applied Materials & Interfaces
    • Analytical Chemistry
    • Langmuir
    • Biomacromolecules,
    • Journal of Chemical Education
    • The Journal of Physical Chemistry (inc. Letters)
  • Royal Society of Chemistry
    • Nanoscale
    • RSC Advances
  • Institute of Physics
    • Biomimetics and Bioinspiration
    • Nanotechnology
    • Physica Scripta
  • Royal Society
    • Philosophical Transactions A
  • Elsevier
    • Advanced Powder Technology
    • Chemical Engineering Research and Design
    • Colloids and Surfaces B: Biointerfaces
    • Journal of Biotechnology
    • Journal of Industrial and Engineering Chemistry
    • Sensors and Actuators B: Chemical
  • Springer
    • Journal of Nanoparticle Research
  • Peer-reviewed Conferences
    • Chemeca

I am also an Evaluator for the Executive Agency for Higher Education, Research, Development and Innovation Funding, Romania and the Royal Society of Chemistry, UK.


Qualifications

  • PhD, University of Leeds - UK
  • Bachelor of Science (Honours)(Biochemistry), University of Surrey - UK

Keywords

  • analytical chemistry
  • antimicrobial peptides
  • biomimetic polymers
  • colloids
  • environmental chemistry
  • inorganic chemistry
  • nanoparticles
  • particle technology
  • physical chemistry
  • silica
  • surface science

Languages

  • English (Mother)
  • Spanish (Working)

Fields of Research

Code Description Percentage
030304 Physical Chemistry of Materials 25
090406 Powder and Particle Technology 50
030306 Synthesis of Materials 25

Professional Experience

UON Appointment

Title Organisation / Department
Casual Academic University of Newcastle
School of Environmental and Life Sciences
Australia

Academic appointment

Dates Title Organisation / Department
1/01/2011 -  Membership - American Chemical Society American Chemical Society
United States
1/01/2011 - 1/12/2013 Fellow University of Newcastle
School of Environmental and Life Sciences
Australia
1/01/2007 -  Membership - Royal Society of Chemistry Royal Society of Chemistry
Australia
1/10/2001 - 1/09/2002 Experimental Officer Covance

Teaching

Code Course Role Duration
CHEM2610 Environmental Chemistry
The University of Newcastle
Environmental science is the foundation of the increased environmental understanding today and chemistry plays a major role in this. The properties and reactions of substances in the environment can profoundly influence the world we live in. These substances may be natural or man-made, and there is increasing interest in the interface between man-made systems and the natural environment. Understanding of the chemical basis of environmental science is developed in this course via studies in the areas of water, earth and atmosphere.
Course coordinator 20/03/2017 - 16/07/2017
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (1 outputs)

Year Citation Altmetrics Link
2011 Neville FC, Millner P, 'Fabrication and characterization of bioactive thiol-silicate nanoparticles', Nanoscale Biocatalysis: Methods and Protocols, Springer, New York 131-145 (2011) [B1]
Citations Scopus - 1

Journal article (21 outputs)

Year Citation Altmetrics Link
2017 Hyde EDER, Moreno-Atanasio R, Neville FC, 'Fabrication of Magnetic Core PEI-Silica Shell Particles', Materials Research Bulletin, (2017)
DOI 10.1016/j.materresbull.2017.02.045
Co-authors Emily Hyde, Roberto Moreno-Atanasio
2016 Neville F, Dixon L, Hyde EDER, 'A comparative study of hydrophobic silica particle synthesis', Advanced Powder Technology, 27 2317-2323 (2016) [C1]

© 2016 The Society of Powder Technology Japan The process to commercially synthesise silica particles with specific properties is a topic of ongoing research since their use in i... [more]

© 2016 The Society of Powder Technology Japan The process to commercially synthesise silica particles with specific properties is a topic of ongoing research since their use in industrial applications including catalysis, coatings and separation materials has dramatically increased in the last decade. Here, silica particles were made using hydrolysed trimethoxymethylsilane (TMOMS) in the presence of either polyethyleneimine or aqueous sodium hydroxide catalysts. This work presents the first in depth study of the effect of TMOMS concentration on silica particles produced by both of these synthetic methods by comparing their size, morphology and chemical structure. The PEI-silica particles were larger in size and greater in yield than the NaOH-silica particles. It was also determined that both species of silica particles are hydrophobic without requiring further surface modification; and that those made with PEI have a higher contact angle, perhaps due to more complete polymerisation. The results demonstrate how relatively facile synthesis routes can wield a high degree of control over the physicochemical properties of silica particles, which is of paramount importance in silica production process intensification.

DOI 10.1016/j.apt.2016.07.007
Co-authors Emily Hyde
2016 Hyde EDER, Seyfaee A, Neville F, Moreno-Atanasio R, 'Colloidal Silica Particle Synthesis and Future Industrial Manufacturing Pathways: A Review', Industrial and Engineering Chemistry Research, 55 8891-8913 (2016) [C1]

© 2016 American Chemical Society.Colloidal silica is used in many applications including catalysis, pharmaceuticals, and coatings. Although naturally formed silica materials are ... [more]

© 2016 American Chemical Society.Colloidal silica is used in many applications including catalysis, pharmaceuticals, and coatings. Although naturally formed silica materials are widely available, they are often in forms that are difficult to process or are even harmful to health. Therefore, uniform colloidal silicas are generally manufactured using synthetic chemical processes. While established high temperature gaseous synthesis methods fall out of favor in our energy conscious society, liquid synthesis methods are current industrial leaders. The precipitated silica method provides the majority share of commercially produced specialty silicas with its economic advantages predicted to continue to grow in the future. The biomimetic method and microemulsion methods of synthesis provide a superior level of surface chemistry and morphological control than current industrial processes and are the major focus of current silica synthesis research. Movement toward more tailor-made products and ecologically friendly production methods will likely provide incentive for biomimetic methods, in particular, to take more of a market share. However, the lack of procedures to viably scale up the biomimetic and microemulsion methods still forms significant gaps in the literature. In this review, the current methods of colloidal silica synthesis are discussed alongside significant models and mechanisms of silica formation.

DOI 10.1021/acs.iecr.6b01839
Citations Scopus - 3Web of Science - 2
Co-authors Emily Hyde, Roberto Moreno-Atanasio
2016 Moreno-Atanasio R, Gao Y, Neville F, Evans GM, Wanless EJ, 'Computational analysis of the selective capture of binary mixtures of particles by a bubble in quiescent and fluid flow', Chemical Engineering Research and Design, 109 354-365 (2016) [C1]

© 2016. The Institution of Chemical Engineers.This paper presents a computer simulation analysis of the selective capture of binary particle mixtures by a central bubble, as infl... [more]

© 2016. The Institution of Chemical Engineers.This paper presents a computer simulation analysis of the selective capture of binary particle mixtures by a central bubble, as influenced by the relative strength of the hydrophobic interaction assigned to each type of particle. The analysis was carried out for a quiescent fluid using two different configurations of initial particle positions, namely: spherical (particles released from within a spherical shell surrounding the bubble) and top (particles released from a horizontal plane located above the bubble) distributions. The top distribution was also used to study the effect of fluid velocity (< 0.05 m/s). The results show that in the case of a quiescent fluid the collection efficiency was greater for the top distribution than for the spherical one. In addition, when the strength of the hydrophobic force was less than the net particle weight, particles easily detached from the bubble surface. In the presence of fluid flow the collection efficiency followed an exponential decay with the fluid velocity and a quadratic relationship with an effective cross-section for the particle-bubble collision. The latter closely follows the collision models in the literature. Importantly, we have shown that selective capture only occurs when one type of particle possesses a hydrophobic force magnitude close to or less than the net particle weight, while the hydrophobic force for the second type needs to be much larger than the net weight of the particle. Therefore, we have concluded that selectivity does not depend solely on the hydrophobicity differences, but also requires that one type of particle has to be weakly interacting with the bubble.

DOI 10.1016/j.cherd.2016.01.035
Citations Scopus - 1
Co-authors Geoffrey Evans, Roberto Moreno-Atanasio, Erica Wanless
2015 Seyfaee A, Neville F, Moreno-Atanasio R, 'Experimental results and theoretical modeling of the growth kinetics of polyamine-derived silica particles', Industrial and Engineering Chemistry Research, 54 2466-2475 (2015) [C1]

© 2015 American Chemical Society.Polyamine-derived silica particles are proposed to grow due to primary particle (<25 nm) aggregation. On the basis of material balance, we propos... [more]

© 2015 American Chemical Society.Polyamine-derived silica particles are proposed to grow due to primary particle (<25 nm) aggregation. On the basis of material balance, we propose an aggregation model to predict the kinetics of polyamine-derived silica formation. The model is based on a rate equation consisting of two terms, representing both the production and aggregation of primary particles. The modeled rate constants were found to be a function of the concentration of silica precursor and biomimetic catalyst. Our experimental results agree with our model and suggest that the cube root of the silica precursor concentration is linearly proportional to particle diameter, as well as that below a critical concentration (~25 mM) no particles will be formed. If the concentration of reagents was high enough to produce particles with diameters greater than ~350 nm, other populations of particles, each of them growing at different rates, were necessary to describe the overall particle diameter observed, which was modeled as the average diameter of these different populations.

DOI 10.1021/acs.iecr.5b00093
Citations Scopus - 1Web of Science - 1
Co-authors Roberto Moreno-Atanasio
2015 Hyde EDE, Moreno-Atanasio R, Millner PA, Neville F, 'Surface charge control through the reversible adsorption of a biomimetic polymer on silica particles.', J Phys Chem B, 119 1726-1735 (2015) [C1]
DOI 10.1021/jp5100439
Citations Scopus - 7Web of Science - 6
Co-authors Emily Hyde, Roberto Moreno-Atanasio
2014 Seyfaee A, Moreno-Atanasio R, Neville F, 'High-resolution analysis of the influence of reactant concentration on nucleation time and growth of polyethyleneimine-trimethoxymethylsilane particles', Colloid and Polymer Science, (2014) [C1]

High-resolution dynamic light scattering (DLS), scanning electron microscopy (SEM), time-lapse photography, and attenuated total reflectance Fourier transform infrared spectroscop... [more]

High-resolution dynamic light scattering (DLS), scanning electron microscopy (SEM), time-lapse photography, and attenuated total reflectance Fourier transform infrared spectroscopy were used to analyze the growth kinetics of polyethyleneimine (PEI)-silica particles fabricated from the condensation of hydrolyzed trimethoxymethylsilane (TMOMS) and PEI/phosphate buffer (PEI/PB). Depending on the concentration of hydrolyzed TMOMS and PEI/PB, three stages were identified. We observed the existence of a nucleation time that has never been reported in the literature when TMOMS has been used. During this nucleation time, particles of less than 25 nm were detected using in situ DLS measurements taken every 15 s (high resolution), a DLS time-scale resolution not previously reported. In addition, the length of the nucleation time depended mainly on the PEI/PB concentration, but also TMOMS concentration. The growth stage was evident from the rapid increase of particle size with time. Due to the high resolution of the DLS measurements, a peak could be observed in the particle diameter during particle growth, which corresponds to a secondary population of particles required for the larger particles to further increase in size. Finally, during the equilibrium region, particles reached their maximum diameter that was independent of the concentration of PEI/PB and only changed with concentration of hydrolyzed TMOMS. © 2014 Springer-Verlag Berlin Heidelberg.

DOI 10.1007/s00396-014-3312-y
Citations Scopus - 4Web of Science - 4
Co-authors Roberto Moreno-Atanasio
2013 Neville F, Seyfaee A, 'Real-time monitoring of in situ polyethyleneimine-silica particle formation.', Langmuir, 29 14681-14690 (2013) [C1]
DOI 10.1021/la403040u
Citations Scopus - 9Web of Science - 10
2013 Neville F, Murphy T, Wanless EJ, 'The formation of polyethyleneimine-trimethoxymethylsilane organic-inorganic hybrid particles', COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 431 42-50 (2013) [C1]
DOI 10.1016/j.colsurfa.2013.04.022
Citations Scopus - 7Web of Science - 8
Co-authors Erica Wanless
2012 Neville FC, Mohd Zin AB, Jameson GJ, Wanless EJ, 'Preparation and characterization of colloidal silica particles under mild conditions', Journal of Chemical Education, 89 940-942 (2012) [C1]
Citations Scopus - 7Web of Science - 9
Co-authors Graeme Jameson, Erica Wanless
2011 Neville FC, Broderick MJF, Gibson T, Millner PA, 'Fabrication and activity of silicate nanoparticles and nanosilicate- entrapped enzymes using polyethyleneimine as a biomimetic polymer', Langmuir, 27 279-285 (2011) [C1]
DOI 10.1021/la1033492
Citations Scopus - 21Web of Science - 21
2010 Neville FC, Ivankin A, Konovalov O, Gidalevitz D, 'A comparative study on the interactions of SMAP-29 with lipid monolayers', Biochimica et Biophysica Acta - Biomembranes, 1798 851-860 (2010) [C1]
DOI 10.1016/j.bbamem.2009.09.017
Citations Scopus - 15Web of Science - 13
2009 Neville F, Pchelintsev NA, Broderick MJF, Gibson T, Millner PA, 'Novel one-pot synthesis and characterization of bioactive thiol-silicate nanoparticles for biocatalytic and biosensor applications', Nanotechnology, 20 1-11 (2009) [C1]
DOI 10.1088/0957-4484/20/5/055612
Citations Scopus - 13Web of Science - 15
2008 Neville FC, Hodges CS, Ishitsuka Y, Lee KYC, Konovalov O, Waring AJ, et al., 'Protegrin interaction with lipid monolayers: Grazing incidence X-ray diffraction and X-ray reflectivity study', Soft Matter, 4 1665-1674 (2008) [C1]
DOI 10.1039/b718295c
Citations Scopus - 28Web of Science - 26
2008 Pchelintsev NA, Neville F, Millner PA, 'Biomimetic silication of surfaces and its application to preventing leaching of electrostatically immobilized enzymes', Sensors and Actuators B: Chemical: international journal devoted to research and development of physical and chemical transducers, 135 21-26 (2008) [C1]
DOI 10.1016/j.snb.2008.07.015
Citations Scopus - 15Web of Science - 15
2007 Neville F, Vakurov A, Broderick M, Millner P, 'Small solutions for greener chemistry', EBR - European Biopharmaceutical Review, 108-114 (2007) [C3]
2007 Neville F, Gidalevitz D, Kale G, Nelson A, 'Electrochemical screening of anti-microbial peptide LL-37 interaction with phospholipids', BIOELECTROCHEMISTRY, 70 205-213 (2007) [C1]
DOI 10.1016/j.bioelechem.2006.07.006
Citations Scopus - 10Web of Science - 10
2006 Hodges CS, Neville F, Konovalov O, Hammond RB, Gidalevitz D, Hamley IW, 'Structural analysis of PEO-PBO copolymer monolayers at the air-water interface', LANGMUIR, 22 8821-8825 (2006) [C1]
DOI 10.1021/la060632k
Citations Scopus - 8Web of Science - 8
2006 Neville F, Hodges CS, Liu C, Konovalov O, Gidalevitz D, 'In situ characterization of lipid A interaction with antimicrobial peptides using surface X-ray scattering', BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1758 232-240 (2006) [C1]
DOI 10.1016/j.bbamem.2006.01.025
Citations Scopus - 19Web of Science - 18
2006 Neville F, Cahuzac M, Konovalov O, Ishitsuka Y, Lee KYC, Kuzmenko I, et al., 'Lipid headgroup discrimination by antimicrobial peptide LL-37: Insight into mechanism of action', BIOPHYSICAL JOURNAL, 90 1275-1287 (2006) [C1]
DOI 10.1529/biophysj.105.067595
Citations Scopus - 81Web of Science - 79
2004 Neville F, Cahuzac M, Nelson A, Gidalevitz D, 'The interaction of antimicrobial peptide LL-37 with artificial biomembranes: epifluorescence and impedance spectroscopy approach', JOURNAL OF PHYSICS-CONDENSED MATTER, 16 S2413-S2420 (2004) [C1]
DOI 10.1088/0953-8984/16/26/014
Citations Scopus - 19Web of Science - 16
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Conference (13 outputs)

Year Citation Altmetrics Link
2016 Seyfaee A, Hyde EDER, Aubin J, Moreno-Atanasio R, Neville F, 'Effect of mixing on bioinspired polyethyleneimine-silica particle formation', CHEMECA 2016: Chemical Engineering - Regeneration, Recovery and Reinvention (2016) [E1]
Co-authors Emily Hyde, Roberto Moreno-Atanasio
2016 Neville F, Moreno-Atanasio R, 'DEM Simulations of Magnetic-silica Core-shell Particle Chain Formation', CHEMECA 2016: Chemical Engineering - Regeneration, Recovery and Reinvention (2016) [E1]
Co-authors Roberto Moreno-Atanasio
2016 Dickinson JE, Neville F, Ireland P, Galvin K, 'Uncoupling the inherent bubble-liquid hydrodynamics of conventional ion flotation', CHEMECA 2016: Chemical Engineering - Regeneration, Recovery and Reinvention (2016) [E1]
Co-authors Kevin Galvin, Peter Ireland
2015 Hyde E, Seyfaee A, Moreno-Atanasio R, Aubin J, Neville F, 'Covalent surface modification of biomimetic silica particles', Proceedings of APCCHE 2015 Congress Incorporating Chemeca 2015 (2015) [E1]
Co-authors Emily Hyde, Roberto Moreno-Atanasio
2015 Seyfaee A, Hyde E, Aubin J, Moreno-Atanasio R, Neville F, Neville F, 'Investigation of polymeric nuclei and their role in biomimetic silication: Effect of physical conditions', Proceedings of APCCHE 2015 Congress Incorporating Chemeca 2015 (2015) [E1]
Co-authors Roberto Moreno-Atanasio, Emily Hyde
2015 Sharpe M, Doran M, Neville F, Di Maio FP, Di Renzo A, Moreno-Atanasio R, 'Influence of the fluid shear rate on the breakage of magnetic particle chain', Proceedings of APCCHE 2015 Congress Incorporating Chemeca 2015 (2015) [E1]
Co-authors Roberto Moreno-Atanasio
2012 Neville FC, Moreno-Atanasio R, 'Magnetic interactions of core-shell composite particles: A combined experimental and simulation approach', Chemeca 2012 : Quality of life through chemical engineering (2012) [E1]
Co-authors Roberto Moreno-Atanasio
2011 Neville FC, Murphy TI, Webber GB, Wanless EJ, Jameson GJ, 'Fabrication and characterisation of biomimetic silicate nanoparticles', Chemeca 2011: Engineering a Better World (2011) [E1]
Co-authors Grant Webber, Erica Wanless, Graeme Jameson
2007 Broderick M, Neville F, Gibson T, Millner P, 'Practical nanobiotechnology: Functional nanoparticle production using silaffin R5 peptide', JOURNAL OF BIOTECHNOLOGY (2007)
DOI 10.1016/j.jbiotec.2007.07.020
2007 Millner P, Broderick M, Neville F, Vakurov A, Gibson T, 'Biosilicate and polymeric nanoparticulate solutions for biocatalysis', JOURNAL OF BIOTECHNOLOGY (2007)
DOI 10.1016/j.jbiotec.2007.07.021
Citations Web of Science - 1
2007 Neville F, Broderick M, Gibson T, Millner P, 'Synthesis and activity of nanosilicates and nanosilicate-entrapped enzymes using biomimetic polymers', JOURNAL OF BIOTECHNOLOGY (2007)
DOI 10.1016/j.jbiotec.2007.07.173
Citations Web of Science - 2
2005 Gidalevitz D, Neville F, 'Interaction of antimicrobial peptides with biomimetic membranes', BIOPHYSICAL JOURNAL (2005)
2004 Neville F, Gidalevitz D, 'LL-37lipid interactions in membrane mimics', BIOPHYSICAL JOURNAL (2004)
Show 10 more conferences
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Research Supervision

Number of supervisions

Completed1
Current4

Total current UON EFTSL

PhD1.3

Current Supervision

Commenced Level of Study Research Title Program Supervisor Type
2017 PhD Interactions of Metal Ions With Functionalised Calcium Carbonate Particles PhD (Chemical Engineering), Faculty of Engineering and Built Environment, The University of Newcastle Co-Supervisor
2016 PhD Understanding the Porosity of Silica Particles PhD (Chemical Engineering), Faculty of Engineering and Built Environment, The University of Newcastle Co-Supervisor
2016 PhD Reusable Composites for Enhanced Magnetic Separation of Fine Mineral Particles. PhD (Chemical Engineering), Faculty of Engineering and Built Environment, The University of Newcastle Co-Supervisor
2014 PhD Optimisation of Silica Particle Fabrication and their Surface Properties Through Novel Synthesis Routes PhD (Chemical Engineering), Faculty of Engineering and Built Environment, The University of Newcastle Co-Supervisor

Past Supervision

Year Level of Study Research Title Program Supervisor Type
2017 PhD Experimental and Theoretical Analysis of Polyethyleneimine-silica Particle Formation PhD (Chemical Engineering), Faculty of Engineering and Built Environment, The University of Newcastle Co-Supervisor
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Research Collaborations

The map is a representation of a researchers co-authorship with collaborators across the globe. The map displays the number of publications against a country, where there is at least one co-author based in that country. Data is sourced from the University of Newcastle research publication management system (NURO) and may not fully represent the authors complete body of work.

Country Count of Publications
United Kingdom 17
Australia 13
United States 8
France 7
Italy 1
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Dr Frances Neville

Positions

Conjoint Lecturer
Chemistry
School of Environmental and Life Sciences
Faculty of Science

Casual Senior Research Assistant
Chemistry
School of Engineering
Faculty of Engineering and Built Environment

Casual Academic
Chemistry
School of Environmental and Life Sciences
Faculty of Science

Focus area

Chemistry

Contact Details

Email frances.neville@newcastle.edu.au
Phone (02) 49216458
Fax (02) 49215472
Links Research Networks
Research Networks

Office

Room C.120
Building Chemistry Building
Location Callaghan
University Drive
Callaghan, NSW 2308
Australia
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