Dr Emma Beckett
Casual Academic
School of Environmental and Life Sciences
- Email:emma.beckett@newcastle.edu.au
- Phone: (02) 4348 4158
Studying the science of nutrition
Molecular nutritionist Dr Emma Beckett is exploring the genetic secrets behind microbiomes and whether you really are what you eat.
“A lot of diseases carry a certain dietary risk: but we don’t always know how the food we eat actually causes the risk in the body. I’m interested in working out what’s happening on a molecular level,” Emma explains. Molecular nutrition explores the bi-directional interaction of nutrients with molecules in the body and helps us understand fundamental questions about our health.
This study of nutrients at a cellular level helps to assess how different nutrients interact with molecules in the body, including the bacteria that live in us, such as the gastrointestinal microbiome. Emma is interested in unraveling how our genes, diet and microbiome interact to predispose us to health or disease. “We all eat food, we all have genes, and we all have a microbiome. But it’s a matter of figuring out how our different unique combinations interact to mean some of us stay healthy while others become unwell” explains Emma. “We can do this by studying cohorts of people, measuring what they eat, what versions of genes they have, and which microbes live in their guts. We compare the different profile to the outcomes and make inferences about disease risk. We can also use cell culture to model the gastrointestinal environment and take control of the interactions to uncover the mechanisms.”
Emma's undergraduate study was in biomedical science with an honours year in immunology and microbiology, followed by four years working in asthma and allergy research at UON. However, for her PhD, Emma wished to explore a new topic that really inspired her: diet and epigenetics. “I’m a twin, so I was already thinking that one of the only things different about me and my twin sister is diet. So I decided that I wanted to do a project exploring that and found the nutrition group here on the Central Coast to explore my project.”
A 2016 NHMRC Early Career Fellowship came at the perfect time for expanding her career independently of her PhD supervisors. “I can now recruit students and look to explore the complex interactions between diet, the microbiome, genetics and epigenetics – with the aim of leading to a better understanding of our risk for, and the effective treatment of, diet-related disease.”
Emma’s current research brings her previous work experience together with her undergraduate and postgraduate by assessing gene-nutrient interactions. “I’m interested in how the genes you have can influence how you taste, process or detect food in your body. But also about how the food you eat changes the way your genes are expressed.”
As part of this study, Emma is studying the gastrointestinal microbiome: “I want to see how it’s not only affected by diet, but how it affects diet. I want to see how different genes that you have to detect your food affect your microbiome, how your microbiome is comprised (what bacteria it’s composed of) and how that impacts on disease risk.”
Spreading the good news about science
Along with her research, Emma is passionate about science communications and outreach. She’s a committee member of Pint of Science Australia and presented at the sold out premiere event in Newcastle in May 2016 – one of many researchers sharing science in pubs around the globe. Emma is also sought after as a media commentator and in October 2016 featured on ABC’s Ockham’s Razor busting the myths of superfoods.
“It’s not just that I have a passion for science,” Emma explains. “I’m very passionate about appropriate use and communication of science. I get quite distressed when science gets twisted by marketing, or when people use bad science to make money or take money off people. And nutrition is an area where there’s a lot of misinformation, and a lot of twisting of information, and a lot of money to be made. The whole ‘dieting’ industry is a huge industry where a lot of money is made.”
Emma is working to bust the myths around nutrition and to teach people how to critique the information they’re given about our diets. “Nutrition’s really hard because everyone eats food, and so everyone’s a stakeholder,” Emma says. “This is great, because people are invested, but it also means that everyone has an opinion and that makes it difficult because then people think ‘well, my neighbour lost weight on the paleo diet, so obviously the paleo diet’s healthy’. But weight loss is only one part of health – and when it comes to the paelo diet all I’ll say is that cavemen didn’t have to worry about colon cancer because they died at 30…”
“It’s really hard to break through the anecdotal basis for people’s beliefs in diets and I think a lot of that involves trying to help people critique the science that’s delivered to them,” Emma says.
“The average nutrition consumer doesn’t know how to pull apart the science – so those who do have the power need to use it.”
The bulk of Emma’s sci-comms work focusses on how the science of nutrition is interpreted. “You’ll see a news item that says ‘New study shows that butter is better than margarine’ but if you actually read the study you’ll see that is not what it says. The definition of what is better, and you’ve got to remember that it’s all in the context of the overall diet, who the people are, and what else they’re eating, you can’t blame the media for wanting a good story, and you can’t blame the scientists who put out the media release but you’ve got to be able to give people the tools to understand the science and cut through the marketing and the headline.”
International inspiration
With the title of Dr very fresh on Emma’s profile, it’s refreshing to hear that she had a very positive time as a Higher Degree Research candidate. “I had the best PhD experience,” Emma enthuses. “I have no complaints about my PhD experience at all and managed to complete it in four years and 10 days.”
While completing her PhD Emma took the opportunity to apply for International experiences that enabled her to learn from the world’s greatest minds. “I apply for everything,” Emma says with a smile.
A highlight of Emma’s career so far is her selection for the visiting fellowship at the National Institutes of Health in the USA. “It was on the Adam Berry Memorial Scholarship. Each year the Australian Academy of Science sends one PhD student to the US to spend three months working at the NIH to gain collaborative experience,” Emma says.
This award had poignant significance for Emma as Adam was a young Australian scientist working at the NIH who died in a car accident while he was there so his parents established the scholarship in his honour. Emma found out she’d won the award shortly after losing her brother in a car accident so it remains a big source of inspiration and a tribute to her tenacity. It also compelled her to aim high when applying for experiences.
Emma was selected from a very competitive field to meet with Nobel Laureates at both the Eighth HOPE meeting in Tokyo and in the 65th Meeting with Nobel Laureates in Lindau, Germany. “The imposter syndrome is big in science, so being able to talk one-on-one with Nobel-winning scientists and finding out that they’ve all been there before is very levelling. It was great as so many of them were talking about their failures. For example. Martin Chalfie, one of the world’s leading scientists, quit science because his undergraduate experiment failed and became a janitor. After being a janitor for a few years he went back to science and discovered that he wasn’t bad at science – he just had a bad project. But it’s also about luck, a lot were in the right place at the right time to hit on the right project – that reminds you that it’s not all in your hands and it’s okay to fail. New opportunities will come to you.”
Not only does Emma put her hand up for opportunities, she actively seeks them and doesn’t self-censor herself on opportunities. Applying for everything not only gives you practice at applying – it gives you practice at failing Emma notes. “People really underrate how much failure is a part of being a researcher,” Emma explains. “If we knew an experiment was going to work, it wouldn’t be called an experiment. Just because you don’t prove your hypothesis doesn’t mean it was flawed or you failed. You can’t take it personally, you just need to refine your hypothesis and move on.”
Studying the science of nutrition
Dr Emma Beckett is exploring the genetic secrets behind microbiomes and whether you really are what you eat.
Career Summary
Biography
Dr Emma Beckett has a multi-faceted research background, with qualifications and experience in nutrition, epidemiology, science management, biomedical sciences, immunology and microbiology.
Emma is interested nutrition and interactions, including the interactions between nutrition and genetics, environment, and lifestyle. Gene-nutrient interactions invovled the study of both how genetic variance alters the bodies responses to nutrition (nutrigenetics), and how nutrients influence gene expression (nutrigenomics) via direct interactions and modification of epigenetic marks. Lifestyle and environment interactions with nutrients include exposures like our microbiomes, sunlight, tastants, pollution and physical activity and also the environment in which we make food choices. By unravelling this complex web of interactions we can determine how these factors act together to modify our risk of chronic and later-life-onset diseases.
Career highlights include selection by the Australian Academy of Science to attend two prestigious meetings with Nobel Laureates: The 65th Lindau Nobel Laureates Meeting in Germany in 2015, and the 8th HOPE Meeting with Nobel Laureates in Japan in 2016. In 2014 Emma was a Visiting Fellow at the National Institute of Environmental and Health Sciences (NIEHS), a division of the US National Institutes of Health (NIH), thanks to the Australian Academy of Sciences and the NIH trust. There she worked with Dr Stephanie London and Dr Bonnie Joubert on maternal dietary exposures and DNA methylation in offspring.
Emma completed her PhD, in 2016, as a joint project between the Faculty of Science at the University of Newcastle and the CSIRO Food and Nutrition Flagship. She was an NHRMC Early Career Fellow from 2017 to 2020 and has been program convenor of the Food Science and Human Nutrition Degrees since 2021.
Emma is also a passionate science communicator. She has written articles for The Conversation, The Newcastle Herald, Lateral Magazine, and ABC. She appears regularly on local and national radio, and at public events. Emma’s science communication work focuses on empowering the public to interpret nutrition research, to help make informed decisions without falling prey to marketing hype. In 2017 she was named as a NSW Young Tall Poppy, in recognition of both her research and communication work. In 2019 she won Early Career Researcher awards from the University of Newcastle Excellence Awards, The UON Alumni Awards and the Faculty of Science.
Qualifications
- Doctor of Philosophy, University of Newcastle
- Bachelor of Biomedical Sciences, University of Newcastle
- Bachelor of Biomedical Sciences (Hons), University of Newcastle
- Graduate Diploma in Clinical Epidemiology, University of Newcastle
- Master of Science Management, University of Newcastle
- Graduate Certificate of Human Nutrition, Deakin University
Keywords
- Biomedical Science
- Epidemiology
- Epigenetics
- Food Science
- Genetics
- Immunology & Microbiology
- Nutrition
- Nutrition Science
- Science Management
Fields of Research
Code | Description | Percentage |
---|---|---|
321003 | Nutrigenomics and personalised nutrition | 25 |
321004 | Nutritional science | 50 |
420208 | Nutritional epidemiology | 25 |
Professional Experience
UON Appointment
Title | Organisation / Department |
---|---|
Casual Academic | University of Newcastle School of Environmental and Life Sciences Australia |
Casual Academic - Online Development (HEPP) | University of Newcastle Learning and Teaching Australia |
Senior Lecturer | University of Newcastle School of Environmental and Life Sciences Australia |
Membership
Dates | Title | Organisation / Department |
---|---|---|
1/1/2016 - | Committee Member Nutrition Society of Australia (Newcastle Branch) | Nutrition Society of Australia (Newcastle Branch) Australia |
1/11/2014 - | Committee Member - Institutional Biosafety Committee | The University of Newcastle Australia |
Professional appointment
Dates | Title | Organisation / Department |
---|---|---|
15/7/2008 - 1/3/2012 | Research Assistant and Laboratory Manager | The University of Newcastle Immunology and Microbiology, School of Biomedical Sciences and Pharmacy Australia |
Awards
Award
Year | Award |
---|---|
2020 |
Student Engagement Award Faculty of Science | University of Newcastle |
2019 |
Early Career Research & Innovation Excellence Award, Faculty of Science, The University of Newcastle. Faculty of Science | University of Newcastle |
2019 |
Research Excellence Early Career Researcher Award, University of Newcastle Excellence Awards. The University of Newcastle |
2019 |
Beryl Nashar Early Career Research Achiever, UON Alumni Awards. The University of Newcastle Alumni |
Distinction
Year | Award |
---|---|
2017 |
Finalist, UON alumni awards - Beryl Nashar Young Researcher 2017 The University of Newcastle Alumni |
Prize
Year | Award |
---|---|
2017 |
Higher Degree by Research Excellence Award Faculty of Science and Information Technology,The University of Newcastle |
2017 |
NSW Young Tall Poppy AIPS (Australian Institute of Policy and Science) |
2016 |
AMP Tomorrow Maker AMP Foundation |
2007 |
Faculty of Health Medal Faculty of Health, University of Newcastle |
Research Award
Year | Award |
---|---|
2016 |
Australian Academy of Science and Japan Society for the promotion of Science HOPE Fellowship Japan Society for the Promotion of Science/Australian Academy of Science (Japan) |
2016 |
Best Oral Presentation – Central Coast Local Health District Research Symposium, 2016. Central Coast Local Health District |
2016 |
Best Scientific Abstract poster prize – Nutrition in Medicine conference, 2016. Australasian College of Nutritional and Environmental Medicine |
2015 |
Travel Award, Annual Meeting of the Nutrition Society of Australia, Wellington, 2015. Nutrition Society of Australia |
2015 |
Science Pathways CSL Regional Travel Award, Adelaide, 2015. EMCR Forum, Australian Academy of Science |
2015 |
Best Oral Presentation Award – Nutrition Society of Australia and New Zealand Joint Annual Scientific Meeting, Wellington, December, 2015. Nutrition Society of Australia |
2015 |
Best Oral Presentation Award – Annual Meeting of the Nutrition Society (Newcastle Branch), 2015 Nutrition Society of Australia (Newcastle Branch) |
2015 |
Best Oral Abstract Presentation – Nutrition in Medicine Conference, Melbourne, 2015. Australasian College of Nutritional and Environmental Medicine |
2015 |
Outstanding Poster Award – International Society for Nutrigenetics and Nutrigenomics International Society for Nutrigenetics and Nutrigenomics |
2014 |
Nutrition Society of Australia Annual Scientific Meeting Travel Award, Hobart, 2014. Nutrition Society of Australia |
2014 |
International Society for Nutrigenetics and Nutrigenomics Conference Registration Fee Award, Gold Coast, 2014. International Society for Nutrigenetics and Nutrigenomics |
2014 |
Best Oral Presentation Award – Annual Meeting of the Nutrition Society (Newcastle), 2014. Nutrition Society of Australia (Newcastle Branch) |
Scholarship
Year | Award |
---|---|
2017 |
Ian Potter Foundation Travel Award Ian Potter Foundation |
2016 |
Student Conference Scholarship- Nutrition in Medicine conference, Sydney, 2016. Australasian College of Nutritional and Environmental Medicine |
2015 |
Student Conference and Travel Scholarship- Nutrition in Medicine conference, Melbourne, 2015. Australasian College of Nutritional and Environmental Medicine |
2015 |
RHD Conference travel scholarship Faculty of Science and Information Technology, The University of Newcastle | Australia |
2015 |
Science and Industry Endowment Fund – Australian Academy of Science (SIEF-AAS) Fellowships to the Lindau Nobel Laureates Meetings. Australian Academy of Sciences |
2014 |
Adam J Berry Memorial Scholarship Australian Academy of Sciences |
2012 |
CSIRO OCE PhD Scholarship CSIRO - Commonwealth Scientific and Industrial Research Organisation |
2007 |
Vice Chancellor's Honours Scholarship The University of Newcastle |
2006 |
School of Biomedical Sciences Summer Vacation Scholarship The University of Newcastle |
2002 |
University of Newcastle Foundation Undergraduate Scholarship The University of Newcastle |
Invitations
Keynote Speaker
Year | Title / Rationale |
---|---|
2019 | Australian Academy of Science Nutrition Decadal Plan Launch |
2017 | Emerging Issues in Science and Society |
Panel Participant
Year | Title / Rationale |
---|---|
2015 | Invited delegate Junkee Junket |
2015 | Panel - Feeding the 9.5 Billion in 2050 - 65th Lindau Nobel Laureates Meeting |
Participant
Year | Title / Rationale |
---|---|
2017 | Theo Murphy High Flyers Think Tank, Rethinking food and nutrition science, Australian Academy of Science. |
2017 | Theo Murphy High Flyers Think Tank, Rethinking food and nutrition science, Australian Academy of Science. |
Speaker
Year | Title / Rationale |
---|---|
2017 | University of Sydney Chemical Society |
Teaching
Code | Course | Role | Duration |
---|---|---|---|
FSHN1020 |
Food and Nutrients II UoN |
Course Coordinator | 17/4/2017 - 24/7/2019 |
HUBS1108 |
Musculoskeletal Anatomy for Podiatry The University of Newcastle |
Tutor | 28/2/2013 - 30/7/2016 |
FSHN1020 |
Introduction to Nutrition Science and Applications School of Environmental and Life Sciences, University of Newcastle |
Course Coordinator | 1/1/2020 - 10/4/2030 |
NURS3101 |
Foundations of Professional Practice 3A The University of Newcastle |
Tutor | 4/3/2014 - 31/7/2016 |
HUBS1108 |
Musculoskeletal Anatomy for Podiatry The University of Newcastle |
Tutor | 11/3/2013 - 31/7/2016 |
FSHN3020 |
Nutrition in Health and Disease UoN Faculty of Science |
Course Coordinator | 1/1/2019 - 1/1/0001 |
FSHN1010 |
Food and Nutrients I Faculty of Science and Information Technology, The University of Newcastle | Australia |
Course Coordinator | 18/7/2017 - 18/12/2017 |
FSHN3060 |
Nutrition for the Lifecycle UoN Faculty of Science |
Course Coordinator | 1/1/2019 - 1/1/0001 |
Publications
For publications that are currently unpublished or in-press, details are shown in italics.
Chapter (6 outputs)
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2019 |
Beckett EL, Lucock M, Veysey M, Joubert BR, 'Maternal folate and DNA methylation in offspring', Handbook of Nutrition, Diet, and Epigenetics 1727-1746 (2019) Folate plays a critical role in DNA methylation as it is a key source of methyl donors via the one-carbon metabolism cycle. Folate supplementation is recommended during the perico... [more] Folate plays a critical role in DNA methylation as it is a key source of methyl donors via the one-carbon metabolism cycle. Folate supplementation is recommended during the periconceptional period for the prevention of neural tube defects in offspring. However, maternal folate levels during pregnancy may also influence the risk of many other conditions in offspring, but the underlying mechanisms involved are unclear. As such, it is important to investigate the possible association between maternal folate status and disease risk that act via modulation of the methylome. Improving methods and technologies available for profiling DNA methylation has allowed for rapidly expanding investigations in this field; however, limitations in study design remain. On the available evidence, global DNA methylation does not appear to be associated with maternal folate status in cord blood samples, but this response may be tissue specific as correlations have been found in fetal brains and adult murine intestines. Several studies have shown differential locus-specific methylation in response to maternal folate status. However, results may vary depending on the assay methods employed, including different assessments of the methylome, different measures of folate status, and cohort composition. Although maternal folate status is linked to disease risk, additional research is required to link this modulation of the methylome to altered health and disease outcomes.
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2019 |
Beckett EL, Veysey M, Yates Z, Lucock M, 'Modulation of microRNA by vitamin D in cancer studies', Handbook of Nutrition, Diet, and Epigenetics, Springer, Cham 1747-1768 (2019) [B1]
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2019 |
Beckett E, Lucock M, 'Flour Fortification and the Prevention of Neural Tube Defects (NTDs)', Flour and Breads and their Fortification in Health and Disease Prevention, Academic Press, Cambridge, MA 435-442 (2019) [B1]
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2018 |
Beckett EL, Lucock M, Veysey M, Joubert BR, 'Maternal Folate and DNA Methylation in Offspring', Handbook of Nutrition, Diet, and Epigenetics, Springer Nature, Cham, Switzerland (2018) [B1]
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Show 3 more chapters |
Journal article (76 outputs)
Year | Citation | Altmetrics | Link | ||||||||
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2024 |
Valencic E, Beckett E, Collins CE, Seljak BK, Bucher T, 'Changing the default order of food items in an online grocery store may nudge healthier food choices', APPETITE, 192 (2024) [C1]
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2024 |
Jones P, Blumfield M, Beckett E, Marshall S, Abbott K, Duve E, Fayet-Moore F, 'Real world evidence on the characteristics of regular and intermittent users of a very-low calorie diet program and associations with measures of program success, health, and quality of life', Obesity Science & Practice, 10 (2024) [C1]
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2023 |
Brasington N, Bucher T, Beckett ELL, 'Frequency of Convenience Cooking Product Use Is Associated with Cooking Confidence, Creativity, and Markers of Vegetable Intake', NUTRIENTS, 15 (2023) [C1]
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2023 |
Barnett AG, Borg DN, Glasziou P, Beckett E, 'Is requiring Research Integrity Advisors a useful policy for improving research integrity? A census of advisors in Australia', Accountability in Research, 1-19 [C1]
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2023 |
Ferraris C, Scarlett CJ, Bucher T, Beckett EL, 'Liking of salt is associated with depression, anxiety, and stress.', Chem Senses, 48 (2023) [C1]
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2023 |
Bucher T, Malcolm J, Mukhopadhyay SP, Vuong Q, Beckett E, 'Consumer acceptance of edible coatings on apples: The role of food technology neophobia and information about purpose', Food Quality and Preference, 112 105024-105024 (2023) [C1]
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2023 |
Ferraris C, Scarlett CJ, Veysey M, Lucock M, Bucher T, Beckett EL, 'Salt-Taste Polymorphism TRPV1-rs8065080 Is Associated with Increased Likelihood of Depression in an Elderly Cohort.', Lifestyle Genom, 16 224-236 (2023) [C1]
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2023 |
Valencic E, Beckett E, Collins CE, Korou ic Seljak B, Bucher T, 'SnackTrack-An App-Based Tool to Assess the Influence of Digital and Physical Environments on Snack Choice.', Nutrients, 15 (2023) [C1]
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2023 |
Valencic E, Beckett E, Collins CE, Korousic B, Bucher T, 'Digital nudging in online grocery stores: A scoping review on current practices and gaps', TRENDS IN FOOD SCIENCE & TECHNOLOGY, 131 151-163 (2023) [C1]
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2022 |
Brasington N, Bucher T, Beckett EL, 'Correlations between Convenience Cooking Product Use and Vegetable Intake', NUTRIENTS, 14 (2022) [C1]
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2022 |
Lucock MD, Jones PR, Veysey M, Thota R, Garg M, Furst J, et al., 'Biophysical evidence to support and extend the vitamin D-folate hypothesis as a paradigm for the evolution of human skin pigmentation', American Journal of Human Biology, 34 (2022) [C1] Objective: To test the ¿vitamin D-folate hypothesis for the evolution of human skin pigmentation.¿. Methods: Total ozone mapping spectrometer (TOMS) satellite data were used to ex... [more] Objective: To test the ¿vitamin D-folate hypothesis for the evolution of human skin pigmentation.¿. Methods: Total ozone mapping spectrometer (TOMS) satellite data were used to examine surface UV-irradiance in a large (n¿= 649) Australian cross-sectional study population. Genetic analysis was used to score vitamin D- and folate-related gene polymorphisms (n¿= 22), along with two pigmentation gene variants (IRF4-rs12203592/HERC2-rs12913832). Red cell folate and vitamin D3 were measured by immunoassay and HPLC, respectively. Results: Ultraviolet radiation (UVR) and pigmentation genes interact to modify blood vitamin levels; Light skin IRF4-TT genotype has greatest folate loss while light skin HERC2-GG genotype has greatest vitamin D3 synthesis (reflected in both TOMS and seasonal data). UV-wavelength exhibits a dose¿response relationship in folate loss within light skin IRF4-TT genotype (305 > 310 > 324 > 380 nm). Significant vitamin D3 photosynthesis only occurs within light skin HERC2-GG genotype, and is maximal at 305 nm. Three dietary antioxidants (vitamins C, E, and ß-carotene) interact with UVR and pigmentation genes preventing oxidative loss of labile reduced folate vitamers, with greatest benefit in light skin IRF4-TT subjects. The putative photosensitiser, riboflavin, did not sensitize red cell folate to UVR and actually afforded protection. Four genes (5xSNPs) influenced blood vitamin levels when stratified by pigmentation genotype; MTHFR-rs1801133/rs1801131, TS-rs34489327, CYP24A-rs17216707, and VDR-ApaI-rs7975232. Lightest IRF4-TT/darkest HERC2-AA genotype combination (greatest folate loss/lowest vitamin D3 synthesis) has 0% occurrence. The opposing, commonest (39%) compound genotype (darkest IRF4-CC/lightest HERC2-GG) permits least folate loss and greatest synthesis of vitamin D3. Conclusion: New biophysical evidence supports the vitamin D-folate hypothesis for evolution of skin pigmentation.
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2022 |
Ford EA, Frost ER, Beckett EL, Roman SD, McLaughlin EA, Sutherland JM, 'Transcriptomic profiling of neonatal mouse granulosa cells reveals new insights into primordial follicle activation .', Biol Reprod, 106 503-514 (2022) [C1]
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2022 |
Ford EA, Peters AE, Roman SD, McLaughlin EA, Beckett EL, Sutherland JM, 'A scoping review of the information provided by fertility smartphone applications', Human Fertility, 25 625-639 (2022) [C1] The growth of smartphone application use across areas of female reproductive health has led to increased interest into their functions and benefits. This scoping review aims to de... [more] The growth of smartphone application use across areas of female reproductive health has led to increased interest into their functions and benefits. This scoping review aims to determine the nature and extent of the peer-reviewed literature presented on fertility-based apps, to identify the reliability of the information within the apps, and to determine the ability of this information to educate users. A systematic search of six databases was conducted in April 2020, returning a total of 21,158 records. After duplicate removal, title and abstract screening exclusionary steps, 27 records were reviewed and charted. Records covered a variety of reproductive health themes including contraception, sexual health, and family planning, and used a range of methodologies. The accuracy of fertility information within the apps reported in these studies was variable, but overall there was a lack of depth in the coverage of content in apps. It was common for studies in this review to base fertile window algorithms on stringent cycle length and variability requirements, limiting the applicability of information delivered to users. Furthermore, studies from app affiliates often lacked collaborations with researchers, minimising the potential for fertility knowledge improvements integrated across the suite of female reproductive health apps.
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2022 |
Jones PR, Brasington N, Garland M, Bucher T, Beckett EL, 'Vegetable content & variety of convenience cooking product recipes: an online audit of Australian supermarket products', INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION, 73 307-314 (2022) [C1]
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2021 |
Turner A, Veysey M, Keely S, Scarlett CJ, Lucock M, Beckett EL, 'Genetic Variation in the Bitter Receptors Responsible for Epicatechin Detection Are Associated with BMI in an Elderly Cohort', NUTRIENTS, 13 (2021) [C1]
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2021 |
Kaur K, Sculley D, Veysey M, Lucock M, Wallace J, Beckett EL, 'Bitter and sweet taste perception: relationships to self-reported oral hygiene habits and oral health status in a survey of Australian adults', BMC ORAL HEALTH, 21 (2021) [C1]
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2021 |
Ferraris C, Turner A, Scarlett C, Veysey M, Lucock M, Bucher T, Beckett EL, 'Association between Sour Taste SNP KCNJ2-rs236514, Diet Quality and Mild Cognitive Impairment in an Elderly Cohort', Nutrients, 13 719-719 [C1]
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2021 |
Kim RY, Sunkara KP, Bracke KR, Jarnicki AG, Donovan C, Hsu AC, et al., 'microRNA-21-mediated SATB1/S100A9/NF-kappa B axis promotes chronic obstructive pulmonary disease pathogenesis', SCIENCE TRANSLATIONAL MEDICINE, 13 (2021) [C1]
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2021 |
Ferraris C, Turner A, Scarlett CJ, Veysey M, Lucock M, Bucher T, Beckett EL, 'Sour Taste SNP KCNJ2-rs236514 and Differences in Nutrient Intakes and Metabolic Health Markers in the Elderly', FRONTIERS IN NUTRITION, 8 (2021) [C1]
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2021 |
Brasington N, Jones P, Bucher T, Beckett EL, 'Correlations between Self-Reported Cooking Confidence and Creativity and Use of Convenience Cooking Products in an Australian Cohort', NUTRIENTS, 13 (2021) [C1]
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2021 |
Frost ER, Ford EA, Taylor G, Boeing S, Beckett EL, Roman SD, et al., 'Two alternative methods for the retrieval of somatic cell populations from the mouse ovary', MOLECULAR HUMAN REPRODUCTION, 27 (2021) [C1]
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2021 |
Kaur K, Turner A, Jones P, Sculley D, Veysey M, Lucock M, et al., 'A Cross-Sectional Study of Bitter-Taste Receptor Genotypes, Oral Health, and Markers of Oral Inflammation', Oral, 1 122-138 (2021) [C1]
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2020 |
Turner A, Bond DR, Vuong QV, Chalmers A, Beckett EL, Weidenhofer J, Scarlett CJ, 'Elaeocarpus reticulatus fruit extracts reduce viability and induce apoptosis in pancreatic cancer cells in vitro', Molecular Biology Reports, 47 2073-2084 (2020) [C1]
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2020 |
Jones P, Lucock M, Chaplin G, Jablonski NG, Veysey M, Scarlett C, Beckett E, 'Distribution of variants in multiple vitamin D-related loci (DHCR7/NADSYN1, GC, CYP2R1, CYP11A1, CYP24A1, VDR, RXRa and RXR ) vary between European, East-Asian and Sub-Saharan African-ancestry populations', Genes and Nutrition, 15 (2020) [C1]
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2020 |
Jones P, Lucock M, Scarlett CJ, Veysey M, Beckett E, 'Environmental UVR levels and skin pigmentation gene variants associated with folate and homocysteine levels in an elderly cohort', International Journal of Environmental Research and Public Health, 17 (2020) [C1]
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2020 |
Ford E, Beckett EL, Roman S, McLaughlin EA, Sutherland J, 'Advances in human primordial follicle activation and premature ovarian insufficiency.', Reproduction, 159 R15-R29 (2020) [C1]
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2020 |
Jones P, Lucock M, Martin C, Thota R, Garg M, Yates Z, et al., 'Independent and interactive influences of environmental UVR, vitamin D levels, and folate variant MTHFD1-RS2236225 on homocysteine levels', Nutrients, 12 (2020) [C1]
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2020 |
Turner A, Veysey M, Keely S, Scarlett CJ, Lucock M, Beckett EL, 'Intense sweeteners, taste receptors and the gut microbiome: A metabolic health perspective', International Journal of Environmental Research and Public Health, 17 1-18 (2020) [C1]
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2020 |
Ford EA, Roman SD, McLaughlin EA, Beckett EL, Sutherland JM, 'The association between reproductive health smartphone applications and fertility knowledge of Australian women', BMC Women's Health, 20 (2020) [C1]
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2020 |
Ferraris C, Turner A, Kaur K, Piper J, Veysey M, Lucock M, Beckett EL, 'Salt Taste Genotype, Dietary Habits and Biomarkers of Health: No Associations in an Elderly Cohort', Nutrients, 12 (2020) [C1]
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2019 |
Jones P, Lucock M, Scarlett CJ, Veysey M, Beckett EL, 'Folate and Inflammation links between folate and features of inflammatory conditions', Journal of Nutrition and Intermediary Metabolism, 18 (2019) [C1]
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2019 |
Kaur K, Sculley D, Wallace J, Turner A, Ferraris C, Veysey M, et al., 'Micronutrients and bioactive compounds in oral inflammatory diseases', Journal of Nutrition and Intermediary Metabolism, 18 (2019) [C1]
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2019 |
Turner A, Chijoff E, Veysey M, Keely S, Scarlett CJ, Lucock M, Beckett EL, 'Interactions between taste receptors and the gastrointestinal microbiome in inflammatory bowel disease', Journal of Nutrition and Intermediary Metabolism, 18 (2019) [C1]
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2019 |
Lucock M, Thota R, Garg M, Martin C, Jones P, Furst J, et al., 'Early lifecycle UV-exposure calibrates adult vitamin D metabolism: Evidence for a developmentally originated vitamin D homeostat that may alter related adult phenotypes', American Journal of Human Biology, 31 (2019) [C1]
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2019 |
Lee YQ, Beckett EL, Sculley DV, Rae KM, Collins CE, Pringle KG, 'The Relationship between Maternal Global Nutrient Restriction during Pregnancy and Offspring Kidney Structure and Function:A Systematic Review of Animal studies.', American Journal of Physiology. Renal Physiology, 316 F1227-F1235 (2019) [C1]
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2018 |
Turner A, Veysey M, Keely S, Scarlett C, Lucock M, Beckett EL, 'Interactions between Bitter Taste, Diet and Dysbiosis: Consequences for Appetite and Obesity.', Nutrients, 10 (2018) [C1]
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2018 |
Lucock M, Jones P, Martin C, Yates Z, Veysey M, Furst J, Beckett E, 'Photobiology of vitamins', Nutrition reviews, 76 512-525 (2018) [C1]
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2018 |
Jones P, Lucock M, Veysey M, Jablonski N, Chaplin G, Beckett E, 'Frequency of folate-related polymorphisms varies by skin pigmentation', AMERICAN JOURNAL OF HUMAN BIOLOGY, 30 (2018) [C1]
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2018 |
Lucock M, Thota R, Garg M, Martin C, Jones P, Furst J, et al., 'Vitamin D and folate: A reciprocal environmental association based on seasonality and genetic disposition', AMERICAN JOURNAL OF HUMAN BIOLOGY, 30 (2018) [C1]
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2018 |
Jones P, Lucock M, Veysey M, Beckett E, 'The vitamin D folate hypothesis as an evolutionary model for skin pigmentation: An update and integration of current ideas', Nutrients, 10 1-13 (2018) [C1]
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2017 |
Beckett EL, Veysey M, Lucock MD, 'Folate and microRNA: Bidirectional interactions', Clinica Chimica Acta, 474 60-66 (2017) [C1]
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2017 |
Lucock M, Beckett E, Martin C, Jones P, Furst J, Yates Z, et al., 'UV-associated decline in systemic folate: implications for human nutrigenetics, health, and evolutionary processes', AMERICAN JOURNAL OF HUMAN BIOLOGY, 29 (2017) [C1]
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2017 |
Beckett EL, Jones P, Veysey M, Duesing K, Martin C, Furst J, et al., 'VDR gene methylation as a molecular adaption to light exposure: Historic, recent and genetic influences', AMERICAN JOURNAL OF HUMAN BIOLOGY, 29 (2017) [C1]
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2017 |
Beckett EL, Martin C, Boyd L, Porter T, King K, Niblett S, et al., 'Reduced plasma homocysteine levels in elderly Australians following mandatory folic acid fortification A comparison of two cross-sectional cohorts', Journal of Nutrition and Intermediary Metabolism, 8 14-20 (2017) [C1]
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2017 |
Beckett EL, Duesing K, Boyd L, Yates Z, Veysey M, Lucock M, 'A potential sex dimorphism in the relationship between bitter taste and alcohol consumption', FOOD & FUNCTION, 8 1116-1123 (2017) [C1]
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2016 |
Jones P, Beckett EL, Yates Z, Veysey M, Lucock M, 'Converging Evolutionary, Environmental and Clinical Ideas on
Folate Metabolism', Exploratory Research and Hypothesis in Medicine, 1 34-41 (2016) [C1]
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2016 |
Joubert BR, den Dekker HT, Felix JF, Bohlin J, Ligthart S, Beckett E, et al., 'Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns', Nature Communications, 7 [C1]
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2016 |
Beckett EL, Le Gras K, Martin C, Boyd L, Ng X, Duesing K, et al., 'Vitamin D receptor polymorphisms relate to risk of adenomatous polyps in a sex-specific manner', Nutrition and Cancer, 68 193-200 (2016) [C1] Vitamin D receptor (VDR) gene polymorphisms may influence risk for adenomatous polyps (AP), a benign precursor to colon cancer, via modulation of vitamin D sensitive pathways, inc... [more] Vitamin D receptor (VDR) gene polymorphisms may influence risk for adenomatous polyps (AP), a benign precursor to colon cancer, via modulation of vitamin D sensitive pathways, including cell proliferation and differentiation. However, results have been mixed and any association remains contentious. Failure to clinically exclude the presence of (AP in control cohorts may contribute to the lack of consensus. Therefore, we assessed the role of the FokI, BsmI, ApaI, and TaqI VDR polymorphisms in modifying risk for AP, adjusting for a range of dietary and lifestyle variables. Blood was collected from colonoscopy patients (n = 258) and VDR polymorphisms assessed by restriction fragment length polymorphism. Dietary habits were estimated from food frequency questionnaires. Odds ratios for AP were calculated by genotype, stratified by sex, and adjusted for age, lifestyle, and dietary factors. FokI was associated with modified risk for AP in males, whereas the BsmI/ApaI/TaqI haplotype was associated with modified risk in females. No interaction was found between VDR variants and vitamin D intake. This study offers novel insight into the potential for VDR genetics to contribute to risk for AP and is the first to demonstrate a sex-specific relationship between these polymorphisms and risk for AP.
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2016 |
Beckett EL, Duesing K, Martin C, Jones P, Furst J, King K, et al., 'Relationship between methylation status of Vitamin D-related genes, Vitamin D levels, and methyl-donor biochemistry', Journal of Nutrition and Intermediary Metabolism, 6 8-15 (2016) [C1] Vitamin D is known for its role in the regulation of gene expression via the Vitamin D receptor, a nuclear transcription factor. More recently, a role for Vitamin D in regulating ... [more] Vitamin D is known for its role in the regulation of gene expression via the Vitamin D receptor, a nuclear transcription factor. More recently, a role for Vitamin D in regulating DNA methylation has been identified as an additional mechanism of modulation of gene expression. How methylation status influences Vitamin D metabolism and response pathways is not yet clear. Therefore, we aimed to assess the relationship between plasma 25-hydroxycholecalciferol (25(OH)D) and the methylation status of Vitamin D metabolism enzyme genes (CYP2R1, CYP27B1 and CYP24A1) and the Vitamin D receptor gene (VDR). This analysis was conducted in the context of dietary Vitamin D, and background methyl donor related biochemistry, with adjustment for several dietary and lifestyle variables. Percentage methylation at CpG sites was assessed in peripheral blood cells using methylation sensitive and dependent enzymes and qPCR. Standard analytical techniques were used to determine plasma 25(OH)D and homocysteine, and serum folate and B12, with the relationship to methylation status assessed using multi-variable regression analysis. CYP2R1 and VDR methylation were found to be independent predictors of plasma 25(OH)D, when adjusted for Vitamin D intake and other lifestyle variables. CYP24A1 was related to plasma 25(OH)D directly, but not in the context of Vitamin D intake. Methyl-group donor biochemistry was associated with the methylation status of some genes, but did not alter the relationship between methylation and plasma 25(OH)D. Modulation of methylation status of CYP2R1, CYP24A1 and VDR in response to plasma 25(OH)D may be part of feedback loops involved in maintaining Vitamin D homeostasis, and may explain a portion of the variance in plasma 25(OH)D levels in response to intake and sun exposure. Methyl-group donor biochemistry, while a potential independent modulator, did not alter this effect.
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2016 |
Camlin NJ, Sobinoff AP, Sutherland JM, Beckett EL, Jarnicki AG, Vanders RL, et al., 'Maternal Smoke Exposure Impairs the Long-Term Fertility of Female Offspring in a Murine Model.', Biol Reprod, 94 39 (2016) [C1]
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2015 |
Lucock M, Jones P, Martin C, Beckett E, Yates Z, Furst J, Veysey M, 'Vitamin D: Beyond Metabolism', Journal of Evidence-Based Complementary and Alternative Medicine, 20 310-322 (2015) [C1] Interest in vitamin D and the VDR gene is increasing as putative roles in human health and evolutionary processes are explored. This review looks beyond the classic biochemistry t... [more] Interest in vitamin D and the VDR gene is increasing as putative roles in human health and evolutionary processes are explored. This review looks beyond the classic biochemistry that links vitamin D to calcium homeostasis; it explores how vitamin D interacts with light in a broader perspective than simple skin photosynthesis. It examines how the vitamin influences circadian rhythm, and how it may have helped drive the evolution of skin pigmentation. To this end, the nutrient¿nutrient relationship with folate is also explored. The VDR gene is additionally examined as a factor in the evolutionary selection of skin depigmentation at higher latitudes to allow vitamin D synthesis. Evidence is given to show that VDR polymorphisms exhibit a latitudinal gradient in allele prevalence consistent with such a paradigm. Overall, the review examines new evo-devo ideas that link light-sensitive vitamins to human health/phenotype, both within and across the lifecycle.
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2015 |
Essilfie A, Horvat JC, Kim RY, Mayall JR, Pinkerton JW, Beckett EL, et al., 'Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma', Thorax Journal, 70 458-467 (2015) [C1]
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2015 |
Lucock M, Yates Z, Martin C, Choi JH, Beckett E, Boyd L, et al., 'Methylation diet and methyl group genetics in risk for adenomatous polyp occurrence', BBA Clinical, 3 107-112 (2015) [C1] Purpose: The aim of this study is to explore whether a methylation diet influences risk for adenomatous polyps (AP) either independently, or interactively with one-carbon metaboli... [more] Purpose: The aim of this study is to explore whether a methylation diet influences risk for adenomatous polyps (AP) either independently, or interactively with one-carbon metabolism-dependent gene variants, and whether such a diet modifies blood homocysteine, a biochemical phenotype closely related to the phenomenon of methylation. Methods: 249 subjects were examined using selective fluorescence, PCR and food frequency questionnaire to determine homocysteine, nine methylation-related gene polymorphisms, dietary methionine, 5-methyltetrahydrofolate, vitamins B6 and B12. Results: 1). Both dietary methionine and 5-methyltetrahydrofolate intake are significantly associated with plasma homocysteine. 2). Dietary methionine is related to AP risk in 2R3R-TS wildtype subjects, while dietary B12 is similarly related to this phenotype in individuals heterozygous for C1420T-SHMT, A2756G-MS and 844ins68-CBS, and in those recessive for 2R3R-TS. 3). Dietary methionine has a marginal influence on plasma homocysteine level in C1420T-SHMT heterozygotes, while B6 exhibits the same effect on homocysteine in C776G-TCN2 homozygote recessive subjects. Natural 5-methyltetrahydrofolate intake is interesting: Wildtype A1298C-MTHFR, heterozygote C677T-MTHFR, wildtype A2756G-MS and recessive A66G-MSR individuals all show a significant reciprocal association with homocysteine. 4). Stepwise regression of all genotypes to predict risk for AP indicated A2756G-MS and A66G-MSR to be most relevant (p= 0.0176 and 0.0408 respectively). Results were corrected for age and gender. Conclusion: A methylation diet influences methyl group synthesis in the regulation of blood homocysteine level, and is modulated by genetic interactions. Methylation-related nutrients also interact with key genes to modify risk of AP, a precursor of colorectal cancer. Independent of diet, two methylation-related genes (A2756G-MS and A66G-MSR) were directly associated with AP occurrence.
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2015 |
Beckett EL, Martin C, Duesing K, Jones P, Furst J, Yates Z, et al., 'Vitamin D receptor genotype modulates the correlation between vitamin D and circulating levels of let-7a/b and vitamin D intake in an elderly cohort', Journal of Nutrigenetics and Nutrigenomics, 7 264-273 (2015) [C1]
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2015 |
Beckett EL, Martin C, Choi JH, King K, Niblett S, Boyd L, et al., 'Folate status, folate-related genes and serum miR-21 expression: Implications for miR-21 as a biomarker', BBA Clinical, 4 45-51 (2015) [C1] Background: Free circulating microRNA (miRNA) in serum may be valuable biomarkers for disease diagnosis and prognosis. miR-21, the archetypal oncogenic miRNA, has been proposed as... [more] Background: Free circulating microRNA (miRNA) in serum may be valuable biomarkers for disease diagnosis and prognosis. miR-21, the archetypal oncogenic miRNA, has been proposed as a biomarker for colorectal cancer and its benign precursor, adenomatous polyps. However, it is now becoming clear that circulating miRNA profiles may be sensitive to lifestyle and environmental influences. Dietary components involved in one-carbon metabolism are particularly well placed to modulate miRNA expression through an influence on DNA methylation pathways. Methods: We investigated the role of methyl group donors (folate, B12, cysteine, homocysteine), polymorphisms of the enzymes of one-carbon metabolism, and serum miR-21 expression in a primary case-control cohort (colonoscopy confirmed adenomatous colon polyps vs controls; n. =. 253) and a secondary cross-sectional cohort (over 65s; n. =. 649). The relationships between these parameters and serum miR-21 levels were assessed, stratified by gender. Conclusions: Serum miR-21 expression was related to occurrence of adenomatous polyps in females, but not males. Folate levels and MTHFR-C677T genotype was associated with miR-21 expression in both genders. Additionally, DHFR-19 del and MSR-A66G were associated with miR-21 expression in females and males, respectively. Stimulation with excess folate increased expression of miR-21 in colon cancer cell lines. General significance: This study demonstrates that serum miR-21 expression correlates with folate status and related genetic status. This may have consequences for the proposed use of miR-21 as a colorectal cancer biomarker.
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2014 |
O'Reilly M, Hansbro PM, Horvat JC, Beckett EL, Harding R, Sozo F, 'Bronchiolar Remodeling in Adult Mice Following Neonatal Exposure to Hyperoxia: Relation to Growth', Anatomical Record, 297 758-769 (2014) [C1] Preterm infants who receive supplemental oxygen for prolonged periods are at increased risk of impaired lung function later in life. This suggests that neonatal hyperoxia induces ... [more] Preterm infants who receive supplemental oxygen for prolonged periods are at increased risk of impaired lung function later in life. This suggests that neonatal hyperoxia induces persistent changes in small conducting airways (bronchioles). Although the effects of neonatal hyperoxia on alveolarization are well documented, little is known about its effects on developing bronchioles. We hypothesized that neonatal hyperoxia would remodel the bronchiolar walls, contributing to altered lung function in adulthood. We studied three groups of mice (C57BL/6J) to postnatal day 56 (P56; adulthood) when they either underwent lung function testing or necropsy for histological analysis of the bronchiolar wall. One group inhaled 65% O2 from birth until P7, after which they breathed room air; this group experienced growth restriction (HE+GR group). We also used a group in which hyperoxia-induced GR was prevented by dam rotation (HE group). A control group inhaled room air from birth. At P56, the bronchiolar epithelium of HE mice contained fewer Clara cells and more ciliated cells, and the bronchiolar wall contained ~25% less collagen than controls; in HE+GR mice the bronchiolar walls had ~13% more collagen than controls. Male HE and HE+GR mice had significantly thicker bronchiolar epithelium than control males and altered lung function (HE males: greater dynamic compliance; HE+GR males: lower dynamic compliance). We conclude that neonatal hyperoxia remodels the bronchiolar wall and, in adult males, affects lung function, but effects are altered by concomitant growth restriction. Our findings may partly explain the reports of poor lung function in ex-preterm children and adults. Anat Rec, 297:758-769, 2014. © 2014 Wiley Periodicals, Inc.
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2014 |
Sobinoff AP, Sutherland JM, Beckett EL, Stanger SJ, Johnson R, Jarnicki AG, et al., 'Damaging legacy: maternal cigarette smoking has long-term consequences for male offspring fertility.', Hum Reprod, 29 2719-2735 (2014) [C1]
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2013 |
Hansbro P, Beckett E, Stevens R, Jarnicki A, Wark P, Foster P, 'A short-term model of COPD identifies a role for mast cell tryptase', EUROPEAN RESPIRATORY JOURNAL, 42 (2013) [C3]
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2013 |
Sobinoff AP, Beckett EL, Jarnicki AG, Sutherland JM, McCluskey A, Hansbro PM, McLaughlin EA, 'Scrambled and fried: Cigarette smoke exposure causes antral follicle destruction and oocyte dysfunction through oxidative stress', TOXICOLOGY AND APPLIED PHARMACOLOGY, 271 156-167 (2013) [C1]
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2013 |
Beckett EL, Stevens RL, Jarnicki AG, Kim RY, Hanish I, Hansbro NG, et al., 'A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis', The Journal of Allergy and Clinical Immunology, 131 752-762 (2013) [C1]
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2012 |
Beckett EL, Phipps S, Starkey MR, Horvat JC, Beagley KW, Foster PS, Hansbro PM, 'TLR2, but not TLR4, is required for effective host defence against chlamydia respiratory tract infection in early life', PLOS One, 7 (2012) [C1]
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2012 |
Starkey MR, Kim RY, Beckett EL, Schilter HC, Shim D, Essilfie A-T, et al., 'Chlamydia muridarum lung infection in infants alters hematopoietic cells to promote allergic airway disease in mice', PLoS One, 7 (2012) [C1]
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2011 |
Jennings PC, Merriman-Jones JA, Beckett EL, Hansbro PM, Jones KT, 'Increased zona pellucida thickness and meiotic spindle disruption in oocytes from cigarette smoking mice', Human Reproduction, 26 878-884 (2011) [C1]
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2011 |
Preston JA, Thorburn AN, Starkey MR, Beckett EL, Horvat JC, Wade MA, et al., 'Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cells', European Respiratory Journal, 37 53-64 (2011) [C1]
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2010 |
Lau JY, Oliver BG, Baraket M, Beckett EL, Hansbro NG, Moir LM, et al., 'Fibulin-1 Is increased in asthma - A novel mediator of airway remodeling?', Plos One, 5 1-13 (2010) [C1]
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2010 |
Hansbro PM, Warner S, Tracey JP, Arzey KE, Selleck P, O'Riley K, et al., 'Surveillance and analysis of avian influenza viruses, Australia', Emerging Infectious Diseases, 16 1896-1904 (2010) [C1]
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Show 73 more journal articles |
Review (3 outputs)
Year | Citation | Altmetrics | Link | ||||||||
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2014 |
Beckett EL, Yates Z, Veysey M, Duesing K, Lucock M, 'The role of vitamins and minerals in modulating the expression of microRNA', Nutrition Research Reviews (2014) [C1] A growing number of studies in recent years have highlighted the importance of molecular nutrition as a potential determinant of health and disease. In particular, the ability of ... [more] A growing number of studies in recent years have highlighted the importance of molecular nutrition as a potential determinant of health and disease. In particular, the ability of micronutrients to regulate the final expression of gene products via modulation of transcription and translation is now being recognised. Modulation of microRNA (miRNA) by nutrients is one pathway by which nutrition may mediate gene expression. MiRNA, a class of non-coding RNA, can directly regulate gene expression post-transcriptionally. In addition, miRNA are able to indirectly influence gene expression potential at the transcriptional level via modulation of the function of components of the epigenetic machinery (DNA methylation and histone modifications). These mechanisms interact to form a complex, bi-directional regulatory circuit modulating gene expression. Disease-specific miRNA profiles have been identified in multiple disease states, including those with known dietary risk factors. Therefore, the role that nutritional components, in particular, vitamins and minerals, play in the modulation of miRNA profiles, and consequently health and disease, is increasingly being investigated, and as such is a timely subject for review. The recently posited potential for viable exogenous miRNA to enter human blood circulation from food sources adds another interesting dimension to the potential for dietary miRNA to contribute to gene modulation. © 2014 The Authors.
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2014 |
Beckett EL, Yates Z, Veysey M, Duesing K, Lucock M, 'The role of vitamins and minerals in modulating the expression of microRNA', Nutrition Research Reviews (2014) Copyright © The Authors 2014. A growing number of studies in recent years have highlighted the importance of molecular nutrition as a potential determinant of health and disease. ... [more] Copyright © The Authors 2014. A growing number of studies in recent years have highlighted the importance of molecular nutrition as a potential determinant of health and disease. In particular, the ability of micronutrients to regulate the final expression of gene products via modulation of transcription and translation is now being recognised. Modulation of microRNA (miRNA) by nutrients is one pathway by which nutrition may mediate gene expression. miRNA, a class of non-coding RNA, can directly regulate gene expression post-transcriptionally. In addition, miRNA are able to indirectly influence gene expression potential at the transcriptional level via modulation of the function of components of the epigenetic machinery (DNA methylation and histone modifications). These mechanisms interact to form a complex, bi-directional regulatory circuit modulating gene expression. Disease-specific miRNA profiles have been identified in multiple disease states, including those with known dietary risk factors. Therefore, the role that nutritional components, in particular, vitamins and minerals, play in the modulation of miRNA profiles, and consequently health and disease, is increasingly being investigated, and as such is a timely subject for review. The recently posited potential for viable exogenous miRNA to enter human blood circulation from food sources adds another interesting dimension to the potential for dietary miRNA to contribute to gene modulation.
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2014 |
Beckett EL, Martin C, Yates Z, Veysey M, Duesing K, Lucock M, 'Bitter taste genetics-the relationship to tasting, liking, consumption and health', Food and Function (2014) [C1] Bitter is the most complex of human tastes, and is arguably the most important. Aversion to bitter taste is important for detecting toxic compounds in food; however, many benefici... [more] Bitter is the most complex of human tastes, and is arguably the most important. Aversion to bitter taste is important for detecting toxic compounds in food; however, many beneficial nutrients also taste bitter and these may therefore also be avoided as a consequence of bitter taste. While many polymorphisms in TAS2R genes may result in phenotypic differences that influence the range and sensitivity of bitter compounds detected, the full extent to which individuals differ in their abilities to detect bitter compounds remains unknown. Simple logic suggests that taste phenotypes influence food preferences, intake and consequently health status. However, it is becoming clear that genetics only plays a partial role in predicting preference, intake and health outcomes, and the complex, pleiotropic relationships involved are yet to be fully elucidated. This journal is
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Conference (44 outputs)
Year | Citation | Altmetrics | Link | |||||
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2024 |
Valencic E, Korou ic Seljak B, Bucher T, Collins CE, Beckett E, 'How to Nudge a Modern Consumer towards Healthier Food Choices', The 14th European Nutrition Conference FENS 2023
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2022 |
Kaur K, Sculley D, Veysey M, Lucock M, Wallace J, Beckett E, 'Associations between bitter and sweet perception and self-reported oral hygiene habits: A cross-sectional survey.', Abstracts of the 45th Annual Scientific Meeting of the Nutrition Society of Australia, Virtual (2022)
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2020 |
Ferraris C, Beckett E, Scott H, 'Sour Taste Genetics (KCNJ2) Predict Cognitive Function in the Elderly', Proceedings, Newcastle, Australia (2020)
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2015 |
Kheir AO, King K, Niblett S, Martin C, Beckett E, Yates Z, et al., 'The relationship between non-alcoholic fatty liver disease and homocysteine', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2015) [E3]
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2015 |
Beckett E, Duesing K, Yates Z, Lucock M, Veysey M, 'miR-21 as a biomarker for adenomatous colon polyps: a potential sex dimorphism', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2015) [E3]
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2015 |
Essilfie A-T, Horvat J, Kim R, Mayall J, Pinkerton J, Beckett E, et al., 'Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid insensitive asthma', JOURNAL OF IMMUNOLOGY, New Orleans, LA (2015)
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2015 |
Veysey M, King K, Niblett SH, Martin C, Beckett EL, Yates ZR, et al., 'Homocysteine Status Is a Predictor of Non-Alcoholic Fatty Liver Disease and Is Genotype Dependent', GASTROENTEROLOGY, Washington, DC (2015) [E3]
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2013 |
Hansbro PM, Horvat JC, Essilfie A-T, Kim RY, Mayall J, Starkey MR, et al., 'Immunomodulatory Effects Of Macrolide Treatment On Experimental Models Of Steroid-Sensitive And Steroid-Resistant Asthma', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)
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2013 |
Hansbro P, Beckett E, Stevens R, Jarnicki A, Kim R, Hanish I, et al., 'A short-term model of COPD identifies a role for mast cell tryptase', JOURNAL OF IMMUNOLOGY, Honolulu, HI (2013) [E3]
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2013 |
Horvat JC, Essilfie A-T, Kim RY, Mayall JR, Starkey MR, Beckett EL, et al., 'MACROLIDES SUPPRESS KEY FEATURES OF EXPERIMENTAL STEROID-SENSITIVE AND STEROID-RESISTANT ASTHMA', RESPIROLOGY (2013) [E3]
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2012 |
Sobinoff AP, Beckett EL, Nixon B, Roman SD, Hansbro PM, McLaughlin EA, 'The impact of maternal cigarette smoke exposure on the male germline', Abstracts. The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2012, Gold Coast, QLD (2012) [E3]
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2012 |
Horvat JC, Essilfie A-T, Kim RY, Mayall JR, Starkey MR, Beckett EL, et al., 'Efficacy of antibiotic-based therapeutic strategies for the treatment of infection-induced, steroid-resistant allergic airways disease', Respirology, Canberra, ACT (2012) [E3]
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2010 |
O'Reilly M, Harding R, Beckett EL, Horvat JC, Hansbro PM, Sozo F, 'Exposure of the immature mouse lung to hyperoxic gas: do structural changes in the lung cause long-term changes in lung function?', 24th Fetal and Neonatal Physiology Workshop of Australia and New Zealand. Program and Abstracts, Wellington, NZ (2010) [E3]
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Show 41 more conferences |
Creative Work (1 outputs)
Year | Citation | Altmetrics | Link | ||
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2021 |
Bucher T, Beckett E, Taiwo A, Vuong Q, Soumi Paul M, Kirkman T, et al., Sustainable Food Future Conference 2021, The University of Newcastle, Ourimbah Campus, Online (2021)
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Other (7 outputs)
Year | Citation | Altmetrics | Link | ||
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2017 | Beckett E, 'Busting the myth that all food additives are bad: a quick guide for label readers', : The Conversation (2017) | ||||
2017 |
Beckett EL, Vuong Q, 'What science says about getting the most out of your tea', The Conversation (2017)
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2016 | Beckett EL, 'Kitchen Science: A salt on the senses', : https://theconversation.com/au (2016) | ||||
Show 4 more others |
Report (1 outputs)
Year | Citation | Altmetrics | Link |
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2017 | Beckett E, Begley A, Boland M, Carter A, Hinkley T, Lassemillante A, et al., 'Empowering Food Choices - 2017 Theo Murphy High Flyers Think Tank Discussion Paper', Australian Academy of Science Theo Murphy High Flyers Think Tank, 15 (2017) |
Grants and Funding
Summary
Number of grants | 18 |
---|---|
Total funding | $937,229 |
Click on a grant title below to expand the full details for that specific grant.
20223 grants / $16,900
100% fruit juice and health effects$9,100
Funding body: Nutrition Research Australia Pty Ltd
Funding body | Nutrition Research Australia Pty Ltd |
---|---|
Project Team | Doctor Emma Beckett |
Scheme | Research Grant |
Role | Lead |
Funding Start | 2022 |
Funding Finish | 2022 |
GNo | G2201080 |
Type Of Funding | C3100 – Aust For Profit |
Category | 3100 |
UON | Y |
Research Consultancy – NRAus & Beckett$6,500
Funding body: Nutrition Research Australia Pty Ltd
Funding body | Nutrition Research Australia Pty Ltd |
---|---|
Project Team | Doctor Emma Beckett |
Scheme | Research Grant |
Role | Lead |
Funding Start | 2022 |
Funding Finish | 2023 |
GNo | G2200878 |
Type Of Funding | C3100 – Aust For Profit |
Category | 3100 |
UON | Y |
Research Consultancy – NRAus & Beckett (Optifast) $1,300
Funding body: Nutrition Research Australia Pty Ltd
Funding body | Nutrition Research Australia Pty Ltd |
---|---|
Project Team | Doctor Emma Beckett |
Scheme | Research Grant |
Role | Lead |
Funding Start | 2022 |
Funding Finish | 2022 |
GNo | G2200974 |
Type Of Funding | C3100 – Aust For Profit |
Category | 3100 |
UON | Y |
20211 grants / $30,000
2022 Women in Research Fellowship 2022 $30,000
Funding body: The University of Newcastle - Research and Innovation Division
Funding body | The University of Newcastle - Research and Innovation Division |
---|---|
Project Team | Dr Emma Beckett |
Scheme | Women in Research Fellowship |
Role | Lead |
Funding Start | 2021 |
Funding Finish | 2022 |
GNo | |
Type Of Funding | Internal |
Category | INTE |
UON | N |
20202 grants / $413,963
Synthetic Biology: from Genomics to Valuable Bioproducts$392,400
Funding body: ARC (Australian Research Council)
Funding body | ARC (Australian Research Council) |
---|---|
Project Team | Professor Brett Neilan, Associate Professor Karl Hassan, Associate Professor Karl Hassan, Doctor Emma Beckett, Doctor Emma Beckett, Aaron Darling, Doctor Gerard Kaiko, Doctor Gerard Kaiko, Professor Marc Wilkins, Professor Marc Wilkins, Belinda Ferrari, Belinda Ferrari, Lawrence Lee, Lawrence Lee, Professor Ian Paulsen, Professor Ian Paulsen, Dr Amy Cain, Dr Amy Cain, Aaron Darling |
Scheme | Linkage Infrastructure Equipment & Facilities (LIEF) |
Role | Investigator |
Funding Start | 2020 |
Funding Finish | 2022 |
GNo | G1900156 |
Type Of Funding | Scheme excluded from IGS |
Category | EXCL |
UON | Y |
Improving vegetable consumption through changing back of pack recipes$21,563
Funding body: Mars Australia Pty Ltd
Funding body | Mars Australia Pty Ltd |
---|---|
Project Team | Doctor Tamara Bucher, Doctor Emma Beckett |
Scheme | Research Grant |
Role | Investigator |
Funding Start | 2020 |
Funding Finish | 2021 |
GNo | G2001174 |
Type Of Funding | C3100 – Aust For Profit |
Category | 3100 |
UON | Y |
20191 grants / $9,970
Light Sensitive Vitamins' Relationship with Environmental and Genetic Factors$9,970
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Miss Patrice Jones, Associate Professor Mark Lucock, Doctor Emma Beckett, Dr Martin Veysey |
Scheme | Greaves Family Postgraduate Top Up Scholarship in Medical Research |
Role | Investigator |
Funding Start | 2019 |
Funding Finish | 2022 |
GNo | G1801307 |
Type Of Funding | C3300 – Aust Philanthropy |
Category | 3300 |
UON | Y |
20181 grants / $10,000
DVCRI Support for ECF$10,000
Funding body: Office of the Senior Deputy Vice- Chancellor Research and Innovation, University of Newcastle
Funding body | Office of the Senior Deputy Vice- Chancellor Research and Innovation, University of Newcastle |
---|---|
Project Team | Emma Beckett |
Scheme | Office of the Senior Deputy Vice- Chancellor Research and Innovation, University of Newcastle |
Role | Lead |
Funding Start | 2018 |
Funding Finish | 2020 |
GNo | |
Type Of Funding | Internal |
Category | INTE |
UON | N |
20179 grants / $446,452
Interactions between diet, microbiome, genetics and epigentics in determining risk for adenomatous polyps$329,527
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Doctor Emma Beckett |
Scheme | Early Career Fellowships |
Role | Lead |
Funding Start | 2017 |
Funding Finish | 2020 |
GNo | G1600442 |
Type Of Funding | C1100 - Aust Competitive - NHMRC |
Category | 1100 |
UON | Y |
UON 2017 Researcher Equipment Grant $49,789
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Doctor Emma Beckett |
Scheme | Researcher Equipment Grants |
Role | Lead |
Funding Start | 2017 |
Funding Finish | 2017 |
GNo | G1701160 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Light Sensitive Vitamins - Relationship with Environmental and Genetic Factors$31,531
Funding body: Central Coast Local Health District
Funding body | Central Coast Local Health District |
---|---|
Project Team | Associate Professor Mark Lucock, Professor Martin Veysey, Doctor Emma Beckett |
Scheme | Research Grant |
Role | Investigator |
Funding Start | 2017 |
Funding Finish | 2020 |
GNo | G1700259 |
Type Of Funding | C2400 – Aust StateTerritoryLocal – Other |
Category | 2400 |
UON | Y |
DVCRI Research Support for ECF$9,680
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Doctor Emma Beckett |
Scheme | NHMRC ECF Support |
Role | Lead |
Funding Start | 2017 |
Funding Finish | 2020 |
GNo | G1700563 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Taste receptor genetics, the microbiota and metabolic disease risk – a pilot study $9,535
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Doctor Emma Beckett, Associate Professor Mark Lucock |
Scheme | Ourimbah Strategic Pilot Grant |
Role | Lead |
Funding Start | 2017 |
Funding Finish | 2017 |
GNo | G1701265 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
To investigate how the way we taste food changes our gut bacteria - as an early career researcher$9,300
Funding body: AMP Limited
Funding body | AMP Limited |
---|---|
Project Team | Doctor Emma Beckett |
Scheme | AMP Tomorrow Fund |
Role | Lead |
Funding Start | 2017 |
Funding Finish | 2017 |
GNo | G1601148 |
Type Of Funding | C3100 – Aust For Profit |
Category | 3100 |
UON | Y |
Equal Futures Award "Oceanic" Leadership in Nutrition Platform$3,000
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Doctor Emma Beckett |
Scheme | Equal Futures Award |
Role | Lead |
Funding Start | 2017 |
Funding Finish | 2017 |
GNo | G1701520 |
Type Of Funding | Scheme excluded from IGS |
Category | EXCL |
UON | Y |
SDVC(RI) Cash Contribution$2,090
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Doctor Emma Beckett |
Scheme | Internal Research Support |
Role | Lead |
Funding Start | 2017 |
Funding Finish | 2017 |
GNo | G1701089 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
11th Congress of the International Society of Nutrigenetics/Nutrigenomics (ISNN), Los Angeles, USA, 16-19 September 2017$2,000
Funding body: Ian Potter Foundation
Funding body | Ian Potter Foundation |
---|---|
Project Team | Doctor Emma Beckett |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 2017 |
Funding Finish | 2017 |
GNo | G1700043 |
Type Of Funding | Scheme excluded from IGS |
Category | EXCL |
UON | Y |
20161 grants / $9,944
Early Career Researcher Equipment Grant Scheme $9,944
Funding body: The University of Newcastle
Funding body | The University of Newcastle |
---|---|
Scheme | Early Career Researcher Equipment Grant Scheme 2016 |
Role | Lead |
Funding Start | 2016 |
Funding Finish | 2016 |
GNo | |
Type Of Funding | Internal |
Category | INTE |
UON | N |
Research Supervision
Number of supervisions
Current Supervision
Commenced | Level of Study | Research Title | Program | Supervisor Type |
---|---|---|---|---|
2022 | PhD | Convenience Cooking Products and Vegetable Consumption: A Novel Potential Solution to Improve Vegetable Intakes in Australia | PhD (Food Science), College of Engineering, Science and Environment, The University of Newcastle | Co-Supervisor |
2022 | PhD | Production and Use of Microbial Enzymes for Processing Dairy Wastes | PhD (Food Science), College of Engineering, Science and Environment, The University of Newcastle | Co-Supervisor |
2022 | PhD | Production, Stability And Safety Of Plant-Based Meat Alternatives | PhD (Food Science), College of Engineering, Science and Environment, The University of Newcastle | Co-Supervisor |
2020 | PhD | Australian Consumer Perceptions, Attitudes and Behaviour Towards Reduced and Alcohol Free Wine | PhD (Food Science), College of Engineering, Science and Environment, The University of Newcastle | Co-Supervisor |
2020 | PhD | Salt, Sour, Mood, and Mind: Relationships between Salt and Sour Taste Qualities and Genetics, and Depression, Anxiety, and Cognitive Impairment | PhD (Food Science), College of Engineering, Science and Environment, The University of Newcastle | Co-Supervisor |
Past Supervision
Year | Level of Study | Research Title | Program | Supervisor Type |
---|---|---|---|---|
2023 | PhD | Use of Information and Communication Technologies, Data and Knowledge to Increase the Impact of Digital Environments on Food Choice | PhD (Nutrition & Dietetics), College of Health, Medicine and Wellbeing, The University of Newcastle | Co-Supervisor |
2022 | PhD | Relationships between Selected Sweet and Bitter-Taste Receptors and Features of Oral Health | PhD (Food Science), College of Engineering, Science and Environment, The University of Newcastle | Principal Supervisor |
2021 | PhD | A Diversified Approach to Improving Fertility Outcomes: Understanding Women’s Fertility Knowledge through Apps and Primordial Follicle Activation in Granulosa Cells | PhD (Medical Biochemistry), College of Health, Medicine and Wellbeing, The University of Newcastle | Co-Supervisor |
2021 | PhD | Interactions between Taste Genetics, Diet and the Gastrointestinal Microbiota: Consequences for Metabolism | PhD (Food Science), College of Engineering, Science and Environment, The University of Newcastle | Principal Supervisor |
2020 | PhD | Vitamin D and Folate: Nutrigenetic Relationships with Environmental Ultraviolet Radiation | PhD (Food Science), College of Engineering, Science and Environment, The University of Newcastle | Principal Supervisor |
2020 | Honours | Frozen Fruits and Vegetables: Consumer Perception and Diet Quality | Food Science & Biotechnology, The University of Newcastle | Principal Supervisor |
2020 | Honours | Relationships between use of meal/recipe bases, cooking skills confidence, and adequate vegetable intake. | Food Science & Biotechnology, The University of Newcastle | Principal Supervisor |
2020 | Honours | Does Food technology neophobia play a role in consumer acceptance of waxed apples | Food Science & Biotechnology, The University of Newcastle, Australia | Co-Supervisor |
2019 | Honours | An investigation into the relationships between taste genetics, diet and indexes of anxiety, depression and cognitive function in an elderly cohort | Food Science & Biotechnology, The University of Newcastle | Principal Supervisor |
Research Collaborations
The map is a representation of a researchers co-authorship with collaborators across the globe. The map displays the number of publications against a country, where there is at least one co-author based in that country. Data is sourced from the University of Newcastle research publication management system (NURO) and may not fully represent the authors complete body of work.
Country | Count of Publications | |
---|---|---|
Australia | 87 | |
United Kingdom | 24 | |
United States | 13 | |
New Zealand | 8 | |
Netherlands | 4 | |
More... |
News
News • 19 Aug 2020
Curious Kids: Why do people get the hiccups and how do you get rid of them?
Hiccups serve no clear purpose. Tadpoles have a hiccup reflex which helps keep their lungs safe while they transition. So our hiccup reflex might be from our amphibian ancestors.
News • 19 May 2020
Unique Women in STEMM scholarship program supports Early Career Researchers
In a first for an Australian university to help redress some of the systemic biases female academics face, the University of Newcastle has awarded fully-funded PhD candidate scholarships to six Women in STEMM Early Career Researchers.
News • 16 Mar 2020
$1 million food facilities unveiled at Ourimbah
The Faculty of Science has opened new $1 million kitchen and laboratory facilities at the University’s Central Coast campus, in a move applauded by the local industry and community.
News • 22 Aug 2017
UON Central Coast research boosted with strategic grants
Six UON research teams will accelerate their research thanks to Central Coast specific research grants.
News • 17 Aug 2017
Outstanding young scientific mind recognised
The significant work of a University of Newcastle (UON) researcher has been recognised at the prestigious 2017 NSW Young Tall Poppy awards, which aim to acknowledge the achievements of Australia’s outstanding young scientific researchers and communicators.
News • 25 Nov 2016
UON researcher a Tomorrow Maker
University of Newcastle researcher Dr Emma Beckett has been awarded a grant in the AMP Tomorrow Fund round.
News • 27 Oct 2016
UON awarded over $5.6 million in NHMRC funding
The University of Newcastle (UON) is delighted to announce the following successful researchers in the latest round of National Health and Medical Research Council funding. With the help of this funding, our researchers aim to tackle a range of health-related issues that impact our communities.
News • 9 Oct 2013
Health check: antioxidants vs free radicals
Health Check: the untrue story of antioxidants vs free radicals
News • 16 Jun 2013
Superfoods: not so super after all?
By Emma Beckett and Zoe Yates, University of Newcastle
Superfoods is a buzzword now part of mainstream food and health language, often touted as miracle foods that cure all ills, stave off ageing and disease, or aid weight loss.
Dr Emma Beckett
Positions
Casual Academic
School of Environmental and Life Sciences
College of Engineering, Science and Environment
Casual Academic - Online Development (HEPP)
Learning and Teaching
Academic Division
Contact Details
emma.beckett@newcastle.edu.au | |
Phone | (02) 4348 4158 |
Links |
Facebook |
Office
Room | SO-109 |
---|---|
Building | Science Offices |
Location | Ourimbah 10 Chittaway Road Ourimbah, NSW 2258 Australia |