Dr Doowon Lee

This paper considers a packet scheduling algorithm using two different priority metrics specified for each service to support integrated services of real-time (RT) and non-real-time (NRT) applications. In particular, as a packet scheduling algorithm for NRT service, this paper proposes a new minimum guaranteed throughput scheduling (MGBRS) algorithm with two priority metrics based on average throughput and the minimum guaranteed throughput requirement and its design objective is to increase the number of NRT service users satisfying the required minimum guaranteed throughput. For the performance evaluation of the proposed MGBRS scheme in a wireless communication system, this paper adopts a transmission structure of an orthogonal frequency division multiple access (OFDMA) system. The simulation results show that the proposed algorithm can provide a significant improvement in terms of increase of the number of NRT service users satisfying the target outage probability and the per-cell total throughput performance by the number of NRT service users meeting the target outage probability is improved. © 2007 IEEE.

Using a high degree of automation, the crystallography core at the Southeast Collaboratory for Structural Genomics (SECSG) has developed a high-throughput protein-to-structure pipeline. Various robots and automation procedures have been adopted and integrated into a pipeline that is capable of screening 40 proteins for crystallization and solving four protein structures per week. This pipeline is composed of three major units: crystallization, structure determination/validation and crystallomics. Coupled with the protein-production cores at SECSG, the protein-to-structure pipeline provides a two-tiered approach for protein production at SECSG In tier 1, all protein samples supplied by the protein-production cores pass through the pipeline using standard crystallization screening and optimization procedures. The protein targets that failed to yield diffraction-quality crystals (resolution better than 3.0 Å) become tier 2 or salvaging targets. The goal of tier 2 target salvaging, carried out by the crystallomics core, is to produce the target proteins with increased purity and homogeneity, which would render them more likely to yield well diffracting crystals. This is performed by alternative purification procedures and/or the introduction of chemical modifications to the proteins (such as tag removal, methylation, surface mutagenesis, selenomethionine labelling etc.). Details of the various procedures in the p ipeline for protein crystallization, target salvaging, data collection/processing and high-throughput structure determination/validation, as well as some examples, are described. © 2005 International Union of Crystallography - all rights reserved.