| 2020 |
Sánchez C, Goodwin GC, Yuz JI, Serón M, Carrasco D, 'Towards a simple sampled-data control law for stably invertible linear systems', IFAC-PapersOnLine, Berlin, Germany (2020) [E1]
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Nova |
| 2017 |
Carrasco DS, Matthews AD, Goodwin GC, Delgado RA, Medioli AM, 'Design of MDIs for Type 1 Diabetes Treatment via Rolling Horizon Cardinality-Constrained Optimisation', IFAC PAPERSONLINE, Toulouse, FRANCE (2017) [E1]
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Nova |
| 2016 |
Phan HV, Carrasco DS, Goodwin GC, Medioli AM, King BR, Smart C, Stephen C, 'A performance limitation for blood glucose regulation in type 1 diabetes accounting for insulin delivery delays', 2016 IEEE 55th Conference on Decision and Control, CDC 2016 (2016) [E1]
The usual recommendation made by clinicians to type 1 diabetics is that they should inject insulin when consuming a meal or, preferably, slightly earlier. However, in practice, in... [more] The usual recommendation made by clinicians to type 1 diabetics is that they should inject insulin when consuming a meal or, preferably, slightly earlier. However, in practice, insulin injection maybe delayed. In this paper we develop a fundamental limit on performance when insulin is delivered at some time other than the preferred time. The paper develops an optimal injection policy which minimizes the maximum blood glucose response whilst ensuring that the minimum response does not fall below a pre-specified level. The result provides a 'gold standard' against which other insulin injection policies can be compared. Implementation issues are also briefly described.
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Nova |
| 2016 |
Phan HV, Goodwin GC, Carrasco DS, Medioli AM, Stephen C, Feuer A, 'Individualization of stochastic models from population statistics for blood glucose regulation in Type 1 diabetes patients', 2016 Australian Control Conference, AuCC 2016, Newcastle, NSW (2016) [E1]
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Nova |
| 2015 |
Carrasco DS, Salgado ME, 'Achievable performance bound for ITSE optimal controller design', 2009 European Control Conference, ECC 2009 (2015)
© 2009 EUCA. This paper proposes a methodology to compute achievable performance bounds in the control of linear, stable discrete-time SISO plants. The performance is measured usi... [more] © 2009 EUCA. This paper proposes a methodology to compute achievable performance bounds in the control of linear, stable discrete-time SISO plants. The performance is measured using a time-weighted cost function (ITSE) that quantifies the control error for a step reference or a step output disturbance. The proposed methodology relies on the use of a function space product that, for stable systems, can be defined in both frequency and time domain. The solution technique requires the expansion of stable functions in orthogonal series. An analytical expression is found for the computation of the optimal coefficients of the expansion. Numerical examples are given to illustrate the results.
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| 2015 |
Goodwin GC, Carrasco DS, Medioli AM, King BR, Stephen C, 'Nonlinear insulin to carbohydrate rule for treatment of type 1 diabetes', IFAC Proceedings Volumes (IFAC-PapersOnline) (2015) [E1]
This paper develops a nonlinear insulin to carbohydrate rule for use by type 1-diabetes patients. The goal is to refine the commonly used Insulin to Carbohydrate Ratio (ICR) formu... [more] This paper develops a nonlinear insulin to carbohydrate rule for use by type 1-diabetes patients. The goal is to refine the commonly used Insulin to Carbohydrate Ratio (ICR) formula. The latter is a strictly linear rule relating carbohydrates consumed to insulin infusion. The new relationship presented in this paper is nonlinear and depends on the availability of a nonlinear dynamic model describing a patient's blood glucose response to food and insulin. Such a model can be obtained by use of nonlinear system identification tools applied to patient test data. The suggested procedure is of similar complexity to the existing standard ICR rule. Hence it has the potential to be of clinical importance especially in developing countries where sophisticated solutions such as an artificial pancreas are unlikely to be used due to excessive cost. Simulations are presented which show that there exists a significant difference between the suggested insulin provided by the rule developed here and that given by the standard ICR rule.
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Nova |
| 2014 |
Carrasco DS, Fu Y, Goodwin GC, King BR, Medioli AM, 'Performance limitations arising in closed loop control of blood glucose in type 1 diabetes', IFAC Proceedings Volumes (IFAC-PapersOnline) (2014) [E1]
This paper presents a preliminary study of performance limitations that arise in the closed-loop control of blood glucose, using an autonomous artificial pancreas. It is shown tha... [more] This paper presents a preliminary study of performance limitations that arise in the closed-loop control of blood glucose, using an autonomous artificial pancreas. It is shown that a major source of limitations is due to model uncertainty, specifically due to the combined effect of the insulin infusion system (IIS), the continuous glucose monitor (CGM) and the human glucose regulatory system. It is argued that the uncertainty associated with each of these elements compromises the achievable closed-loop bandwidth, and, in the presence of disturbances, e.g. meal intake and exercise, the closed-loop response will necessarily be poor. A proposition to overcome this problem is given based on feedforward action.
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Nova |
| 2013 |
Carrasco DS, Goodwin GC, 'The role of asymptotic sampling zero dynamics in the sampled-data control of continuous nonlinear systems', Proceedings of the IEEE Conference on Decision and Control, Florence, Italy (2013) [E1]
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| 2011 |
Carrasco Yanez DS, Goodwin GC, 'An input-output sampled data model for a class of continuous-time nonlinear systems having no finite zeros', 2011 9th IEEE International Conference on Control and Automation (ICCA), Santiago, Chile (2011) [E1]
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| 2011 |
Carrasco Yanez DS, Ljung L, Goodwin GC, Aguero JC, 'On the accuracy of parameter estimation for continuous time nonlinear systems from sampled data', 2011 50th IEEE Conference on Decision and Control and European Control Conference (CDC-ECC), Orlando, FL (2011) [E1]
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| 2011 |
Carrasco Yanez DS, Goodwin GC, 'Preview and feedforward in model predictive control: A preliminary robustness analysis', Proceedings of the 18th IFAC World Congress, 2011, Milano, Italy (2011) [E1]
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| 2011 |
Goodwin GC, Carrasco Yanez DS, Mayne DQ, Salgado ME, Seron MM, 'Preview and feedforward in model predictive control: Conceptual and design issues', Proceedings of the 18th IFAC World Congress, 2011, Milano, Italy (2011) [E1]
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Nova |
| 2010 |
Silva EI, Carrasco DS, 'Upper Bounds on the Best Achievable Performance for time-weighted Cost Functionals', 49TH IEEE CONFERENCE ON DECISION AND CONTROL (CDC), Atlanta, GA (2010)
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