Staff Profile
Career Summary
Biography
Dr. Rick Thorne (PhD 1999) is a postdoctoral researcher sponsored by the HMRI Cancer Research Program and contracted lecturer in the School of Biomedical Sciences & Pharmacy at the University of Newcastle. His major interest involves different families of cell adhesion molecules and how these engage signalling pathways, particularly how these contribute to the development and progression of cancer. These interests overlap with CD36, another signalling molecule with disease functions outside cancer, particularly the metabolic syndrome and related disorders such as diabetes.
Dr. Thorne has over ten years postdoctoral experience beginning with the award of a two year competitive postdoctoral fellowship Brawn Postdoctoral Research Fellow undertaken at the UoN under Prof. Gordon Burns. During that period he was awarded two competitive overseas training schemes through the UICC, an International Cancer Technology Transfer Fellowships undertaken at the ICRF in London, UK (2000) and a Cancer Research Training Course held in Toronto, Canada (2001). Pursing further training he then relocated the UK to take up a three year post as a Postdoctoral Fellow in Training (2002-2004) at the 5* Institute of Cancer Research (ICR, London). This appointment also led to a number of quality publications and first-hand experience as a PhD supervisor and supervisor of graduate student projects for Imperial College (honours equivalent). Following the ICR appointment he returned to UoN under an ARC Australian Postdoctoral Fellowship awarded from 2004-2007 in connection with an ARC Discovery Project. Subsequent to this award he received a three year Cancer Institute NSW fellowship for the period 2008-2010. After a number of years acting as laboratory manager for the Cancer Research Unit, Dr. Thorne inherited the facilities’ of Prof. Burns and now runs this laboratory on an independent basis.
Over the last five years Dr. Thorne has contributed 27 original research articles and one review article. For ten of these publications he is the first, equal contributory or senior author. Within this body of work there is a strong indication of productive collaborations with local, national and international colleagues.
Qualifications
- PhD, University of Newcastle, 27/08/1999
- Bachelor of Science (Honours), University of Newcastle, 30/04/1988
- Bachelor of Science, University of Newcastle, 02/05/1987
Research
Research keywords
- apoptosis
- cell adhesion
- cell signaling
Research expertise
I have been working in laboratory-based science for nearly twenty years with direct hands on experience in vast array of techniques. I have a strong interest in the technical aspects of science, and have been instrumental in obtaining key equipment for my own research work and for the greater benefit of my research colleagues.
A summary of my technical skills and experience is as follows.
Molecular Biology: All DNA manipulations associated with the construction of expression vectors including epitope tagged molecules, fusion proteins, mutants and chimeras, recombinant adenoviruses. DNA and RNA preparation and analysis by southern and northern blotting, PCR, screening assays for cDNA libraries, yeast-2-hybrid assays etc.
Protein analysis and biochemistry: SDS-PAGE, 2D gels, immunoprecipitation, GST-pulldown, immunoblotting, use of radioisotopes, kinase assays, metabolic labeling studies, N-glycan analysis, chromatographic and related biochemical methods, flow cytometry, ELISA assays, protein and enzyme assays.
Imaging: I have developed and manage a microscope facility consisting of a trio of three Zeiss microscopes freely available to all subject to appropriate training. All utilise a common software package (Axiovision) that helps in training of users. I have a great deal of experience in immunofluorescence and confocal microscopic imaging.
The Axioplan 2 is a standard upright miscroscope equipped with colour and monochrome cameras, Apotome imaging device, Colibri 2 illumination system. This is powerful system fitted with a large number of epifluorescence filter sets and high performance objectives. This system is adaptable to almost any specimen on a slide.
The Axiovert 200 is a manual inverted fluorescence microscope fitted with a high resolution monochrome camera. Suitable for general work using cultured cells.
The Cell Observer System is for live cell imaging and more complex scanning tasks. It consists of an automated inverted microscope with scanning stage and an integrated incubator system.
Cell culture and in vitro assays: derivation and maintenance of cell lines, cryopreservation, mycoplasma screening, cell transfection methods, cloning and cell sorting, production and characterization of monoclonal antibodies, cell adhesion, migration and chemotaxis assays, drug toxicity, apoptosis, phagocytosis and cell-mediated immunity assays.
In vivo models: I have developed experimental models for cancer metastasis and immunoscintography in human xenograft models of melanoma, and experimental chemotherapy protocols for an rodent model of acquired drug-resistance in mammary cancer.
Fields of Research
| Code | Description | Percentage |
|---|---|---|
| 060100 | Biochemistry And Cell Biology | 40 |
| 110399 | Clinical Sciences Not Elsewhere Classified | 30 |
| 110199 | Medical Biochemistry And Metabolomics Not Elsewhere Classified | 30 |
Memberships
Committee/Associations (relevant to research).
- Member - American Association of Cancer Research
- Lifetime fellow of organisation - International Union against Cancer (UICC)
Appointments
| Gladys M Brawn Memorial Fellowship The University of Newcastle (Australia) | 01/01/2000 - 01/04/2001 |
Awards
Research Award.
| 2007 |
UICC (Australia) International award to undertake UICC Cancer Research Training Course: Molecular Biology of Solid Tumour Therapeutics. (2001) Sponsored travel and accommodation to Toronto, Ontario, Canada. |
|---|
Invitations
| Dr. A. Obaidat, Department of Pharmacy Jordan University of Science and Technology, King Abdullah II Hospital, Jordan (Invitation to give lectures in Jordan to JUST and to the affiliated King Abdullah II Hospital) | 2006 |
Administrative
Administrative expertise
Membership of the Steering committee of the HMRI Cancer Research Program (2005-current)
Organising committee member and session chairs for the HMRI Translational Cancer Conferences held in 2006 and 2008
Convener of the HMRI CRP seminar program from 2005-2009
HMRI Grant Review Panel Member 2009
Ad hoc representation on various committees at the School and Faculty level acting on behalf of Cancer Researchers and/or the discipline of Medical Biochemistry
Reviewer of project grant applications in Research Infrastructure Block Grant (RIBG) Scheme (2006)
Peer reviewer for both ARC Discovery and NHMRC Project grants since 2007
Peer reviewer for a number of scientific journals including Biochemical Journal, Journal of Lipid Research, Experimental Cell Research, Immunology and Cell Biology, Journal of Signal Transduction, Stem Cell Reviews & Reports and the British Journal of Cancer
Member of the NHMRC GRPs in 2011 and 2012 assessing grants for Cancer Biology & Oncology
Teaching
Teaching expertise
Research Higher Degree Completions
Mr. George Tzircotis (PhD 2005, University of London, UK) co-supervisor
Ms. Kristy Shipman (PhD 2009, University of Newcastle, Australia) co-supervisor
Mr. Mohammad Alkhatatbeh (thesis accepted December, 2012) primary supervisor
Current Research Higher Degree Students
As primary supervisor
Ms. Camila Oliveira (enrolment confirmed, thesis submission due November 2012)
Mr. Alireza Arjmand (enrolment confirmed, thesis submission due February 2012)
Ms. Elham Sadeqzadeh (enrolment confirmed, thesis submission due February 2012)
Mr. Abdulrzag Ahmed (enrolment confirmed, thesis submission due February 2014)
As co-supervisor
Ms. Jiao Li (other supervisors A/Prof. Derek Laver and A/Prof. Dirk Van Helden)
Additionally I have sat on a number of RHD confirmation panels for students from both the School of Biological Sciences and the School of Medicine and Public Health.
Honours (and equivalent) supervision
Ms. Ka Man Emily Chu (Final Year Project, Imperial College London, 2003)
Ms. Dale Anne Boyce (Honours, Bachelor of Biomedical Sciences, University of Newcastle, 2005)
Mr. Andrew James William Weir (Honours, Bachelor of Biomedical Sciences, University of Newcastle, 2007)
Mr. Simon Bone (Honours, Bachelor of Biomedical Sciences, University of Newcastle, 2007)
Mr. Steven Alley (Honours, Bachelor of Biomedical Sciences, University of Newcastle, 2009)
Mr. Tim Kelso (Honours, Bachelor of Biomedical Sciences, University of Newcastle, 2010)
Ms. Anna Timofeeva (Final Year Project, Karolinska Institute, Sweden, 2011)
Undergraduate Teaching experience
Contracted 0.5 lecturing appointment for undergraduate teaching in the School of Biomedical Sciences Bachelor’s program in 2001 and 2012 where I lectured major components of HUBS 2206 (Human Biochemistry and Cell Biology), HUBS 2209 (Human Molecular Science) and supervised associated Laboratory Practical Classes
Course coordinator of HUBS 3409 (Project in Biomedical Sciences) in 2011 and 2012
Grants and Funding
Summary
| Number of grants | 37 |
|---|---|
| Total funding | $5,522,868 |
For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.
Click on a grant title below to expand the full details for that specific grant.
2013 (3 grants)
Functional consequences of epigenetic repression of PIB5PA in melanoma$359,250
Funding Body: Cancer Council NSW
| Project Team | ||
|---|---|---|
| Professor Xu Dong Zhang, Dr Helen Rizos, Doctor Rick Thorne, Doctor Chen Chen Jiang | ||
| Scheme | Role | |
| Research Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $359,250 | 2013 | 2015 |
| GNo:G1200386 | ||
Ultra-Low Temperature Cryogenic Freezer$24,596
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Jude Weidenhofer, Doctor Rick Thorne, Doctor Kathryn Skelding, Doctor Nikki Verrills, Doctor Pradeep Tanwar, Associate Professor Phillip Dickson, Doctor Murray Cairns, Professor Hubert Hondermarck, Professor Xu Dong Zhang, Associate Professor Estelle Sontag, Doctor Chen Chen Jiang, Associate Professor Liz Milward, Doctor Jean-Marie Sontag, Associate Professor Paul Tooney, Doctor Severine Roselli, Doctor Matt Dun, Doctor Chris Dayas, Doctor Lin Kooi Ong, Professor Dirk Van Helden, Mr Ben Copeland, Ms Gabrielle Briggs, Conjoint Professor Leonie Ashman, Professor John Rostas | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $24,596 | 2013 | 2013 |
| GNo:G1201189 | ||
Keystone Meeting: The Hippo Tumor Suppressor Network, Monterey USA, 19-23 May 2013$2,000
Funding Body: University of Newcastle - Faculty of Health
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne | ||
| Scheme | Role | |
| Travel Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $2,000 | 2013 | 2013 |
| GNo:G1300652 | ||
2012 (5 grants)
Targeting Histone Deacetylases to Overcome Resistance of BRAFV600E Melanoma Cells to Apoptosis$346,974
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Professor Xu Dong Zhang, Conjoint Professor Peter Hersey, Dr Tao Liu, Doctor Chen Chen Jiang, Doctor Rick Thorne | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $346,974 | 2012 | 2014 |
| GNo:G1100133 | ||
High-Resolution Isoelectric Phosphoprotein Signalling System for Signalling Research, Biomarker Validation and Drug Development – Equipment Grant$143,394
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Professor Xu Dong Zhang, Professor Hubert Hondermarck, Conjoint Professor Stephen Ackland, Doctor Lisa Lincz, Doctor Jennette Sakoff, Conjoint Professor Leonie Ashman | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $143,394 | 2012 | 2012 |
| GNo:G1200555 | ||
Microscopic illumination system for advanced fluorescent protein technology$34,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Professor Xu Dong Zhang, Doctor Murray Cairns, Doctor Nikki Verrills, Doctor Charles De Bock, Doctor Jude Weidenhofer, Doctor Severine Roselli, Doctor Kathryn Skelding, Conjoint Professor Leonie Ashman, Professor Hubert Hondermarck | ||
| Scheme | Role | |
| Equipment Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $34,000 | 2012 | 2012 |
| GNo:G1100983 | ||
A p53-Mediated Pro-Survival Signaling Pathway in Human Melanoma Progression and Resistance to Treatment$20,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Professor Xu Dong Zhang, Doctor Rick Thorne, Doctor Chen Chen Jiang | ||
| Scheme | Role | |
| Near Miss Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2012 | 2012 |
| GNo:G1200672 | ||
Establishment of Fat1 cadherin as biomarker and unique target for anti-cancer therapy in paediatric acute lymphoblastic leukaemia$20,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Doctor Charles De Bock, Doctor Lisa Lincz | ||
| Scheme | Role | |
| Research Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2012 | 2013 |
| GNo:G1200222 | ||
2011 (1 grants)
IMPLEN NanoPhotometer pearl$10,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Murray Cairns, Associate Professor Paul Tooney, Associate Professor Alan Brichta, Professor John Rostas, Emeritus Professor Patricia Michie, Conjoint Professor Keith Jones, Professor Ulli Schall, Associate Professor Phillip Dickson, Doctor Frederick Walker, Doctor Rick Thorne, Doctor Chris Dayas, Doctor Nikki Verrills, Doctor Janet Holt, Doctor Severine Roselli, Doctor Kathryn Skelding, Doctor Jude Weidenhofer, Associate Professor Liz Milward, Doctor Charles De Bock, Doctor Julie Merriman-Jones, Doctor Jing Qin Wu, Doctor Bing Liu, Mr Dan Johnstone, Ms Belinda Goldie, Ms Natalie Beveridge | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $10,000 | 2011 | 2011 |
| GNo:G1100030 | ||
2010 (6 grants)
Laser microdissection microscopy system for cell and development biology$350,000
Funding Body: ARC (Australian Research Council)
| Project Team | ||
|---|---|---|
| Professor Eileen McLaughlin, Conjoint Professor Keith Jones, Laureate Professor John Aitken, Associate Professor Brett Nixon, Doctor Shaun Roman, Associate Professor Alan Brichta, Doctor Rick Thorne, Doctor Doug Smith, Associate Professor David McCurdy, Conjoint Professor Ray Rose, Professor Christopher Grof, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Doctor Brett Graham, Associate Professor Paul Tooney, Professor Roger Smith, Professor Paul Foster, Professor Trevor Day, Professor Robert Callister | ||
| Scheme | Role | |
| Linkage Infrastructure Equipment & Facilities (LIEF) | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $350,000 | 2010 | 2010 |
| GNo:G0190369 | ||
Laser microdissection microscopy system for cell and development biology$215,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Professor Eileen McLaughlin, Conjoint Professor Keith Jones, Laureate Professor John Aitken, Associate Professor Brett Nixon, Doctor Shaun Roman, Associate Professor Alan Brichta, Doctor Rick Thorne, Doctor Doug Smith, Associate Professor David McCurdy, Conjoint Professor Ray Rose, Professor Christopher Grof, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Doctor Brett Graham, Associate Professor Paul Tooney, Professor Roger Smith, Professor Paul Foster, Professor Trevor Day, Professor Robert Callister | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $215,000 | 2010 | 2010 |
| GNo:G1000874 | ||
Pathogenic Function of Plasma CD36 Mircroparticles in Mediating Complications of Type 2 Diabetes$98,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Doctor Lisa Lincz | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $98,000 | 2010 | 2011 |
| GNo:G0900121 | ||
ABI 7500 Real Time PCR System
$34,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Doctor Nikki Verrills, Doctor Murray Cairns, Associate Professor Paul Tooney, Doctor Doug Smith, Professor Gordon Burns, Conjoint Professor Leonie Ashman, Conjoint Professor Keith Jones, Doctor Charles De Bock, Doctor Chris Dayas, Doctor Brett Graham, Doctor Martin Horan, Doctor Rebecca Lim, Doctor Severine Roselli, Doctor Larisa Bobrovskaya, Doctor Kathryn Skelding, Doctor Frederick Walker, Doctor Jude Weidenhofer, Associate Professor Philip Bolton, Associate Professor Alan Brichta, Professor Robert Callister, Professor Trevor Day, Associate Professor Phillip Dickson, Professor Manohar Garg, Doctor Phil Jobling, Associate Professor Derek Laver, Associate Professor Eugene Nalivaiko, Professor John Rostas | ||
| Scheme | Role | |
| Equipment Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $34,000 | 2010 | 2010 |
| GNo:G1000055 | ||
Electron Multiplier Charge-Coupled Device Camera. Hamamatsu EM-CCD Camera C9100-13$29,079
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Keith Jones, Professor Eileen McLaughlin, Professor Dirk Van Helden, Doctor Rick Thorne | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $29,079 | 2010 | 2010 |
| GNo:G1000052 | ||
AACR 101st Annual Meeting, Washington DC, 17 - 21st April 2010$2,000
Funding Body: University of Newcastle - Faculty of Health
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne | ||
| Scheme | Role | |
| Travel Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $2,000 | 2010 | 2011 |
| GNo:G1000133 | ||
2009 (7 grants)
An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)
| Project Team | ||
|---|---|---|
| Laureate Professor John Aitken, Professor Adam McCluskey, Doctor Mark Baker, Doctor Nikki Verrills, Professor Marcel Maeder, Doctor Xiaojing Zhou, Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman, Conjoint Professor Ray Rose, Professor Hugh Dunstan, Professor Christopher Grof, Professor Roger Smith, Conjoint Professor Peter Gibson, Conjoint Professor Alison Jones, Professor Mike Calford, Conjoint Professor Keith Jones, Doctor Rick Thorne, Emeritus Professor Peter Dunkley, Professor Paul Foster, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Associate Professor Phillip Dickson, Professor John Rostas, Professor Rodney Scott, Associate Professor Paul Tooney, Professor Phil Hansbro, Professor Pablo Moscato, Professor Paul Dastoor, Professor Peter Lewis | ||
| Scheme | Role | |
| Linkage Infrastructure Equipment & Facilities (LIEF) | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $495,000 | 2009 | 2009 |
| GNo:G0189122 | ||
Targeting adaptive mechanisms to endoplasmic reticulum stress in melanoma$491,250
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Professor Xu Dong Zhang, Conjoint Professor Peter Hersey, Doctor Rick Thorne | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $491,250 | 2009 | 2011 |
| GNo:G0188902 | ||
Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000
Funding Body: ARC (Australian Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Keith Jones, Professor Eileen McLaughlin, Laureate Professor John Aitken, Conjoint Professor Ray Rose, Emeritus Professor John Patrick, Conjoint Professor Christina Offler, Associate Professor David McCurdy, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Professor Dirk Van Helden, Doctor Nikki Verrills, Associate Professor Brett Nixon, Doctor Shaun Roman, Associate Professor Yong-Ling Ruan, Doctor Rick Thorne, Professor Mike Calford | ||
| Scheme | Role | |
| Linkage Infrastructure Equipment & Facilities (LIEF) | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $275,000 | 2009 | 2009 |
| GNo:G0189038 | ||
An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)
| Project Team | ||
|---|---|---|
| Laureate Professor John Aitken, Professor Adam McCluskey, Doctor Mark Baker, Doctor Nikki Verrills, Professor Marcel Maeder, Doctor Xiaojing Zhou, Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman, Conjoint Professor Ray Rose, Professor Hugh Dunstan, Professor Christopher Grof, Professor Roger Smith, Conjoint Professor Peter Gibson, Conjoint Professor Alison Jones, Professor Mike Calford, Conjoint Professor Keith Jones, Doctor Rick Thorne, Emeritus Professor Peter Dunkley, Professor Paul Foster, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Associate Professor Phillip Dickson, Professor John Rostas, Professor Rodney Scott, Associate Professor Paul Tooney, Professor Phil Hansbro, Professor Pablo Moscato, Professor Paul Dastoor, Professor Peter Lewis | ||
| Scheme | Role | |
| Linkage Infrastructure Equipment & Facilities (LIEF) Partner funding | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $50,000 | 2009 | 2009 |
| GNo:G0189948 | ||
FACSAria$30,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Doctor Severine Roselli, Professor Xu Dong Zhang, Dr Charles De Bock, Conjoint Professor Peter Hersey, Professor Gordon Burns | ||
| Scheme | Role | |
| Equipment Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $30,000 | 2009 | 2009 |
| GNo:G0189846 | ||
Identification of leukaemic stem cells based upon their expression of a novel surface marker, Fat1$25,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Doctor Lisa Lincz | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $25,000 | 2009 | 2009 |
| GNo:G0189791 | ||
Hunter Cell Biology Meeting, Pokolbin, 24-27 March 2009$600
Funding Body: University of Newcastle - Faculty of Health
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne | ||
| Scheme | Role | |
| Travel Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $600 | 2009 | 2009 |
| GNo:G0190131 | ||
2008 (4 grants)
Involvement of the MIF-CD74-CD44 signalling complex in melanoma progression$600,000
Funding Body: Cancer Institute NSW
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne | ||
| Scheme | Role | |
| Career Development Fellowship | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $600,000 | 2008 | 2010 |
| GNo:G0188173 | ||
Colibri high-performance LED illumination system for fluorescence live cell microscopy$23,225
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Dr Charles De Bock, Professor Xu Dong Zhang, Doctor Lisa Lincz, Professor Gordon Burns, Conjoint Professor Peter Hersey, Professor Dirk Van Helden, Conjoint Professor Keith Jones, Professor Roger Smith | ||
| Scheme | Role | |
| Equipment Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $23,225 | 2008 | 2008 |
| GNo:G0188545 | ||
Biogenesis of circulating plasma microparticles in the metabolic syndrome$8,450
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Doctor Lisa Lincz | ||
| Scheme | Role | |
| Pilot Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $8,450 | 2008 | 2008 |
| GNo:G0189072 | ||
Biogenesis of circulating plasma microparticles in the metabolic syndrome$8,450
Funding Body: University of Newcastle - Faculty of Health
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Doctor Lisa Lincz | ||
| Scheme | Role | |
| Pilot Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $8,450 | 2008 | 2008 |
| GNo:G0189385 | ||
2007 (5 grants)
Characterisation and antibody - mediated targeting of a novel specific marker for T cell all/lymphoblastic lymphoma$564,500
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Professor Gordon Burns, Professor Andrew Boyd, Doctor Rick Thorne, Assoc. Prof Alpha Yap | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $564,500 | 2007 | 2009 |
| GNo:G0186374 | ||
FACSAria - Fluorescence activated cell sorter$300,000
Funding Body: Cancer Institute NSW
| Project Team | ||
|---|---|---|
| Doctor Nikki Verrills, Conjoint Professor Leonie Ashman, Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Alistair Sim, Doctor Rick Thorne, Doctor Jennette Sakoff | ||
| Scheme | Role | |
| Infrastructure Grants | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $300,000 | 2007 | 2007 |
| GNo:G0187666 | ||
HMRI Contribution toward FACSAria - Fluorescence activated cell sorter$52,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Nikki Verrills, Conjoint Professor Leonie Ashman, Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Alistair Sim, Doctor Rick Thorne, Doctor Jennette Sakoff | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $52,000 | 2007 | 2007 |
| GNo:G0188207 | ||
High speed/sensitivity CCD camera$30,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Professor Dirk Van Helden, Professor Eileen McLaughlin, Professor Gordon Burns, Doctor Rick Thorne, Dr Marcus Howlett, Doctor Mohammad Imtiaz, Associate Professor Alan Brichta, Professor Robert Callister, Doctor Brett Graham, Associate Professor Derek Laver, Associate Professor Liz Milward, Doctor John Holdsworth | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $30,000 | 2007 | 2007 |
| GNo:G0188196 | ||
A novel adhesive target involved in the survival of leukaemia cells$20,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Doctor Lisa Lincz | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2007 | 2007 |
| GNo:G0187243 | ||
2006 (2 grants)
Live cell imaging facility$149,100
Funding Body: Cancer Institute NSW
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Doctor Nikki Verrills, Professor Alistair Sim, Professor Gordon Burns | ||
| Scheme | Role | |
| Infrastructure Grants | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $149,100 | 2006 | 2006 |
| GNo:G0186146 | ||
High speed computer for a live cell imaging system$3,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne, Professor Gordon Burns, Doctor Nikki Verrills, Professor Alistair Sim | ||
| Scheme | Role | |
| Equipment Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $3,000 | 2006 | 2006 |
| GNo:G0187279 | ||
2005 (2 grants)
2005 RIBG allocation$32,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne | ||
| Scheme | Role | |
| Research Infrastructure Block Grant (RIBG) | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $32,000 | 2005 | 2005 |
| GNo:G0185802 | ||
Understanding how some cancer cells survive low oxygen tension$8,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $8,000 | 2005 | 2005 |
| GNo:G0184753 | ||
2004 (1 grants)
Investigation of a phagocytic-synapse in the uptake of apoptotic cells$660,000
Funding Body: ARC (Australian Research Council)
| Project Team | ||
|---|---|---|
| Professor Gordon Burns, Professor M Berndt, Professor Andrew Boyd, Professor P Hogg, Doctor Rick Thorne | ||
| Scheme | Role | |
| Discovery Projects | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $660,000 | 2004 | 2006 |
| GNo:G0182803 | ||
2001 (1 grants)
Analysis of a Novel Membrane Insertion Motif in the CD36 Glycoprotein$9,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Doctor Rick Thorne | ||
| Scheme | Role | |
| New Staff Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $9,000 | 2001 | 2001 |
| GNo:G0180732 | ||
Research Supervision
| Number of current supervisions | 6 |
|---|---|
| Total current UoN PhD EFTSL | 2.55 |
For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.
Current Supervision
| Commenced | Proposed Completion | Program | Supervisor Type | Research Title |
|---|---|---|---|---|
| 2011 | 2015 | PhD (Medical Biochemistry) | Principal Supervisor | Roles of Fat in Cadherins in Neuronal Differentiation and in Progression of Neurological Malignancies |
| 2009 | 2013 | PhD (Medical Biochemistry) | Principal Supervisor | Analysis of Post-Translational Modifications of Fat1 Cadherin |
| 2008 | 2012 | PhD (Medical Biochemistry) | Principal Supervisor | The Role of MIF in Melanoma Progression |
| 2008 | 2012 | PhD (Medical Biochemistry) | Principal Supervisor | Analysis of Fat1 Cadherin and Identification of Novel Biomarkers for Acute Leukemia |
| 2007 | 2007 | Honours Biochemistry & Cell Biology University of Newcastle | Principal Supervisor | Role of Fat1 cadherin in melanoma progression |
| 2007 | 2007 | Honours Biochemistry & Cell Biology University of Newcastle | Co-Supervisor | A novel adhesive target involved in acute lympohoblastic leukemia |
Past Supervision
| Year | Program | Supervisor Type | Research Title |
|---|---|---|---|
| 2013 | PhD(Experimental Pharmacology) | Principal Supervisor | Biogenesis of Plasma CD36+Microparticles in Human Diabetes and the Metabolic Syndrome |
| 2008 | PhD (Medicine) | Co-Supervisor | Characterisation of the Multifunctional Protein, CREAP |
| 2005 | Honours Biochemistry & Cell Biology University of Newcastle | Principal Supervisor | Role of Fat1 cadherin in breast cancer metastasis |
| 2005 | PHD Medical Science Institute of Cancer Research, UK (Affilitated to Univeristy of London) | Co-Supervisor | TBA |
Dr Rick Thorne
| Work Phone | (02) 4921 7860 |
|---|---|
| Fax | (02) 4921 7867 |
| Rick.Thorne@newcastle.edu.au | |
| Position | HMRI Research Fellow School of Biomedical Sciences and Pharmacy Faculty of Health and Medicine |
| Focus Area | Medical Biochemistry |
| Office | LS3-33, Life Sciences, Callaghan University Drive Callaghan NSW 2308 Australia |
| URL: | www.newcastle.edu.au/profile/rick-thorne |
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