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Career Summary

Biography

  • 1992, Ph D (Newcastle, Australia)
  • 1999, work as the Project Co-ordinatorof the Marsupial CRC at Newcastle University. Since than, work on the sperm physiology and biochemistry has been published in the premier international journals of reproductive biology and anatomy and a provisional patent (IP Australia Patent Office No.6492).
  • Up to 2003, research has been supported by the Marsupial Cooperative Research Centre in marsupial reproductive biology. My work has been recognized by international peers, and invited to give keynote speech at the International Symposium on Comparative Reproductive Biology in Vertebrates, Sun City, South Africa, in 2001.
  • With the termination of the MCRC in 2004, I had to realign my research career from maruspial reproductive biology to eutherians, so that he can become competitive for NCG funds including linkage grants with industry.
  • Currently, he is appointed as a senior lecturer at the School of Environmental Biology, and joined the Reproduction group at the Discipline of Biological Sciences.

Qualifications

  • PhD, University of Newcastle, 08/05/1992
  • Master of Science (Agriculture), Jiangxi Agriculture University

Research

Research keywords

  • Male Reproductive System
  • Sperm maturation in the epididymis
  • Spermatogenesis

Research expertise

In animal reproductive physiology and biochemistry, specifically in the area of sperm formation in birds and mammals, including marsupials and monotremes. Currently research grants supported the following 4 research fields:

1. Kinetics of Sperm production in mammals and birds

2. Biochemical mechanism of sperm maturation in mammals

3. Separation of X- and Y- chromosome sperm

4. Identification of sperm proteins as contraceptive antigens

Languages

  • Cantonese
  • Mandarin

Fields of Research

CodeDescriptionPercentage
111499Paediatrics And Reproductive Medicine Not Elsewhere Classified65
060803Animal Developmental And Reproductive Biology35

Administrative

Administrative expertise

University ACEC member

Teaching

Teaching keywords

  • Animal Physiology
  • Developmental Biology
  • Human Physiology

Teaching expertise

Lectured on undergraduate courses such as animal physiology and development, reproductive physiology and development, biosciences (human physiology), and animal biology.

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Highlighted Publications

For publications that are currently unpublished or in-press, details are shown in italics.

YearCitationAltmetricsLink
2006Lin M, Lee YH, Xu W, Baker MA, Aitken RJ, 'Ontogeny of tyrosine phosphorylation-signaling pathways during spermatogenesis and epididymal maturation in the mouse', Biology of Reproduction, 75 588-597 (2006) [C1]
2002Lin M, Hess R, Aitken RJ, 'Induction of sperm maturation in vitro in epididymal cell cultures of the tammar wallaby (Macropus eugenii): disruption of motility initiation and sperm morphogenesis by inhibition of actin polymerization', Reproduction, 124 107-117 (2002) [C1]

Co-authors: John Aitken

2004Lin M, Bielanowicz AJ, Fletcher TP, 'Cycle of the seminiferous epithelium in a marsupial species, the brushtail possum (Trichosurus vulpecula), and estimation of its duration', Reproduction Fertility and Development, 16 307-313 (2004) [C1]
2001Scarlett CJ, Lin M, Aitken RJ, 'Actin polymerisation during morphogenesis of the acrosome as spermatozoa undergo epididymal maturation in the tammar wallaby (Macropus eugenii)', Journal of Anatomy, 198 93-101 (2001) [C1]

Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Journal article (27 outputs)

YearCitationAltmetricsLink
2014Goldie BJ, Dun MD, Lin M, Smith ND, Verrills NM, Dayas CV, Cairns MJ, 'Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons.', Nucleic Acids Research, 42 9195-9208 (2014) [C1]
2011Koppers AJ, Mitchell LA, Wang JP, Lin M, Aitken RJ, 'Phosphoinositide 3-kinase signalling pathway involvement in a truncated apoptotic cascade associated with motility loss and oxidative DNA damage in human spermatozoa', Biochemical Journal, 436 687-698 (2011) [C1]
2011Dun MD, Smith ND, Baker MA, Lin M, Aitken RJ, Nixon B, 'The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction', Journal of Biological Chemistry, 286 36875-36887 (2011) [C1]
2009Ren D, Xing Y, Lin M, Wu Y, Li K, Li W, et al., 'Evaluations of boar gonad development, spermatogenesis with regard to semen characteristics, libido and serum testosterone levels based on large white Duroc x Chinese Erhualian crossbred boars', Reproduction in Domestic Animals, 44 913-919 (2009) [C1]
2007Aitken RJ, Nixon B, Lin M, Koppers AJ, Lee YH, Baker MA, 'Proteomic changes in mammalian spermatozoa during epididymal maturation', Asian Journal of Andrology, 9 554-564 (2007) [C1]
2006Lin M, Lee YH, Xu W, Baker MA, Aitken RJ, 'Ontogeny of tyrosine phosphorylation-signaling pathways during spermatogenesis and epididymal maturation in the mouse', Biology of Reproduction, 75 588-597 (2006) [C1]
2004Bennetts LE, Lin M, Aitken RJ, 'Cyclic AMP-Dependent Tyrosine Phosphorylation in Tammar Wallaby (Macropus eugenii) Spermatozoa', Journal of Experimental Zoology. Part A: Comparative Experimental Zoology, 301A 118-130 (2004) [C1]
2004Lin M, Bielanowicz AJ, Fletcher TP, 'Cycle of the seminiferous epithelium in a marsupial species, the brushtail possum (Trichosurus vulpecula), and estimation of its duration', Reproduction Fertility and Development, 16 307-313 (2004) [C1]
2002Zhang X, Lin M, 'Tracing sperm acrosome differentiation in the testis and maturation in the epididymis of the tammar wallaby (Macropus eugenii) with a 45-kDa acrosome-membrane-associated protein', Reproduction Fertility and Development, 14 69-77 (2002) [C1]
2002Lin M, Hess R, Aitken RJ, 'Induction of sperm maturation in vitro in epididymal cell cultures of the tammar wallaby (Macropus eugenii): disruption of motility initiation and sperm morphogenesis by inhibition of actin polymerization', Reproduction, 124 107-117 (2002) [C1]

Co-authors: John Aitken

2001Scarlett CJ, Lin M, Aitken RJ, 'Actin polymerisation during morphogenesis of the acrosome as spermatozoa undergo epididymal maturation in the tammar wallaby (Macropus eugenii)', Journal of Anatomy, 198 93-101 (2001) [C1]
2000Lin M, Jones RC, 'Spermiogenesis and spermiation in a monotreme mammal, the platypus, Ornithorhynchus anatinus', JOURNAL OF ANATOMY, 196 217-232 (2000) [C1]
2000Lin M, Zhang X, Murdoch RN, Aitken RJ, 'In vitro culture of brushtail possum (Trichosurus vulpecula) epididymal epithelium and induction of epididymal sperm maturation in co-culture', Journal of Reproduction and Fertility, 119 1-14 (2000) [C1]

Co-authors: John Aitken

1999Murdoch RN, Jones RC, Wade MA, Lin M, 'The ultrastructure and metabolism of ejaculated tammar wallaby sperm are impaired by swim-up procedures when compared with sperm from the cauda epididymidis', Reproduction Fertility and Development, 11 263-271 (1999) [C1]
1999Lin M, Rodger JC, 'Acrosome formation during sperm transit through the epididymis in two marsupials, the tammar wallaby (Macropus eugenii) and the brushtailpossum (Trichosurus vulpecula)', Journal of Anatomy, 194 223-232 (1999) [C1]

Co-authors: John Rodger

1999Wade MA, Lin M, 'A 33 kDa molecular marker of sperm acrosome differentiation and maturation in the tammar wallaby (Macropus eugenii)', Journal of Reproduction and Fertility, 117 79-88 (1999) [C1]
1998Lin M, Zhang X, Wade MA, Harris MS, Nickel M, 'Isolation of proteins from subacrosomal region of spermatozoa from a marsupial, the tammar wallaby (Macropus eugenii)', Journal of Reproduction and Fertility, 113 257-267 (1998) [C1]

Co-authors: Merrilee Harris

1995Lin M, Thorne MH, Martin ICA, Sheldon BL, Jones RC, 'Development of the gonads in the triploid (ZZW and ZZZ) fowl, Gallus domesticus, and comparison with normal diploid males (ZZ) and females (ZW)', REPRODUCTION FERTILITY AND DEVELOPMENT, 7 1185-1197 (1995)
1995LIN M, THORNE MH, MARTIN ICA, SHELDON BL, JONES RC, 'ELECTRON-MICROSCOPY OF THE SEMINIFEROUS EPITHELIUM IN THE TRIPLOID (ZZZ AND ZZW) FOWL, GALLUS-DOMESTICUS', JOURNAL OF ANATOMY, 186 563-576 (1995)
1994REYNOLDS RJ, LITTLE GJ, LIN M, HEATH JW, 'IMAGING MYELINATED NERVE-FIBERS BY CONFOCAL FLUORESCENCE MICROSCOPY - INDIVIDUAL FIBERS IN WHOLE NERVE TRUNKS TRACED THROUGH MULTIPLE CONSECUTIVE INTERNODES', JOURNAL OF NEUROCYTOLOGY, 23 555-564 (1994)
1993SISTINA Y, LIN M, MATE KE, RODGER JC, 'INDUCTION OF THE MARSUPIAL SPERM ACROSOME REACTION IN-VITRO BY TREATMENT WITH DIACYLGLYCEROLS', JOURNAL OF REPRODUCTION AND FERTILITY, 99 335-341 (1993)
1993LIN M, JONES RC, 'SPERMIOGENESIS AND SPERMIATION IN THE JAPANESE-QUAIL (COTURNIX-COTURNIX-JAPONICA)', JOURNAL OF ANATOMY, 183 525-535 (1993)
1992JONES RC, LIN M, 'ULTRASTRUCTURE OF THE GENITAL DUCT EPITHELIUM OF THE MALE PORT JACKSON SHARK, HETERODONTUS-PORTUSJACKSONI', AUSTRALIAN JOURNAL OF ZOOLOGY, 40 257-266 (1992)
1992LIN M, JONES RC, 'RENEWAL AND PROLIFERATION OF SPERMATOGONIA DURING SPERMATOGENESIS IN THE JAPANESE-QUAIL, COTURNIX-COTURNIX-JAPONICA', CELL AND TISSUE RESEARCH, 267 591-601 (1992)
1990LIN M, JONES RC, 'SPATIAL ARRANGEMENT OF THE STAGES OF THE CYCLE OF THE SEMINIFEROUS EPITHELIUM IN THE JAPANESE-QUAIL, COTURNIX-COTURNIX-JAPONICA', JOURNAL OF REPRODUCTION AND FERTILITY, 90 361-367 (1990)
1990LIN M, JONES RC, BLACKSHAW AW, 'THE CYCLE OF THE SEMINIFEROUS EPITHELIUM IN THE JAPANESE QUAIL (COTURNIX-COTURNIX-JAPONICA) AND ESTIMATION OF ITS DURATION', JOURNAL OF REPRODUCTION AND FERTILITY, 88 481-490 (1990)
1990SUJARIT S, JONES RC, SETCHELL BP, CHATURAPANICH G, LIN M, CLULOW J, 'STIMULATION OF PROTEIN SECRETION IN THE INITIAL SEGMENT OF THE RAT EPIDIDYMIS BY FLUID FROM THE RAM RETE TESTIS', JOURNAL OF REPRODUCTION AND FERTILITY, 88 315-321 (1990)
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Conference (1 outputs)

YearCitationAltmetricsLink
2006Aitken RJ, Baker MA, Lee YH, Lin M, Nixon B, 'Proteomic Changes in Mouse Spermatozoa During Epididymal Transit', Abstracts, Chatel-Guyon, Auvergne, France (2006) [E3]
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Grants and Funding

Summary

Number of grants20
Total funding$807,568

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2014 (1 grants)

Faculty PVC Conference Assistance Grant 2014$2,000
Funding Body: University of Newcastle - Faculty of Science & IT

Project Team
Doctor Minjie Lin
SchemeRole
PVC Conference Assistance GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020142014
GNo:G1401222

2009 (3 grants)

Electron Microscopes for Nanometer-scale Imaging/Microanalysis in the Materials, Biological, Physical, Engineering and Chemical Sciences$650,000
Funding Body: ARC (Australian Research Council)

Electron Microscopes for Nanometer-scale Imaging/Microanalysis in the Materials, Biological, Physical, Engineering and Chemical Sciences$70,000
Funding Body: ARC (Australian Research Council)

The roles of cytoskeletal proteins on the fertilization and embryonic development in a marine invertebrate, Galeolaria caespitose$6,000
Funding Body: Newcastle Innovation

Project Team
Doctor Minjie Lin
SchemeRole
Administered ResearchChief Investigator
Total AmountFunding StartFunding Finish
$6,00020092009
GNo:G0190608

2004 (1 grants)

Development of an in vitro system for studying the maturation of mammalian spermatozoa$10,000
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin, Laureate Professor John Aitken
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020042004
GNo:G0183402

2002 (2 grants)

Identification of sperm-specific actin regulators which control acrosomal shaping in the epididymis$6,500
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin, Conjoint Associate Professor Russell Jones
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$6,50020022002
GNo:G0181360

Visit of Prof W Fu, from 5 August 2002 to 23 September 2002$3,718
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
Visitor GrantChief Investigator
Total AmountFunding StartFunding Finish
$3,71820022002
GNo:G0181900

2001 (3 grants)

Identification of regulators of actin filament assembly and disassembly to shape sperm acrosome.$5,000
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$5,00020012001
GNo:G0180021

The 16th International Symposium on Morphological Sciences, South Africa 22-26 July 2001$2,400
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,40020012001
GNo:G0180748

Third International Conference on Epididymis - Virginia, USA - 29/5/02 - 1/06/02$2,400
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,40020012001
GNo:G0181636

2000 (2 grants)

Using in vitro co-culture systems to investigate the role of actin filaments on sperm maturation in Australian marsupials.$6,500
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$6,50020002000
GNo:G0178941

11th European Workshop on Molecular and Cellular Endocrinology of the Testis.$2,400
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,40020002000
GNo:G0180272

1998 (1 grants)

The culture of epithelial cells from the male reproductive tract of the tammar wallaby and the in vitro maturation of sperm$9,500
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin, Raymond Murdoch
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$9,50019981998
GNo:G0177292

1997 (1 grants)

10th European Workshop on Molecular and Cellular Endocrinology of the testis, Italy 28 March - 1 April 1998$2,400
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,40019971997
GNo:G0180281

1996 (2 grants)

Local regulation of the spermatogenesis in the quail:Secretions of the inhibin and activin during the cycle of the seminiferous epithelium.$7,000
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$7,00019961996
GNo:G0175725

9th European Testis Workshop on Molecular and Cellular Endocrinology - Norway - 14-19/4/96$2,400
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,40019961996
GNo:G0176036

1995 (1 grants)

Local regulation of the spermatogenesis in the quail: Secretions of the inhibin and activin during the cycle of the seminiferours epithelium.$8,000
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$8,00019951995
GNo:G0174846

1994 (2 grants)

Spermatogenesis in the Platypus (Ornithorhynchus anatinus)$4,500
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$4,50019941994
GNo:G0174752

'8th European Workshop on Molecular and Cellular Endocrinology of the Testis', De Panne, Belgium, 27 - 31 March 1994$1,350
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,35019941994
GNo:G0174448

1993 (1 grants)

93GRANT.Spermatogenesis in the Platypus (Ornithorhynchus anatinus)$5,500
Funding Body: University of Newcastle

Project Team
Doctor Minjie Lin
SchemeRole
New Staff GrantChief Investigator
Total AmountFunding StartFunding Finish
$5,50019931993
GNo:G0172888
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Research Supervision

Number of current supervisions2
Total current UoN PhD EFTSL0.9

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20132017PhD (Biological Sciences)Principal SupervisorStudy Spermatogenesis in a Native Marine Invertebrate Galeolaria Caespitosa and Investigate it's Potential as a Biomarker for Marine Pollution
20132017PhD (Biological Sciences)Co-SupervisorDissecting the Molecular Mechanisms of the Oviduct

Past Supervision

YearProgramSupervisor TypeResearch Title
2009PhD (Biological Sciences)Co-SupervisorFunctional Maturation of Mouse Epididymal Spermatozoa
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Dr Minjie Lin

Work Phone(02) 4921 5707
Fax(02) 4921 5472
Email
PositionSenior Lecturer
School of Environmental and Life Sciences
Faculty of Science and Information Technology
The University of Newcastle, Australia
Focus AreaBiological Sciences
Office
LS4-49,
Life Sciences,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/minjie-lin