Staff Profile
Dr Janet Holt
ARC DECRA FELLOW
School of Biomedical Sciences and Pharmacy
EditCareer Summary
Biography
Dr Holt completed her PhD at the University of Newcastle 2002-2006 investigating gene expression in the developing mammalian ovary. Post-doctoral research areas have included nuclear signalling in the developing mammalian testis and currently, control of meiosis and molecular mechanisms underlying aneuploidy in the mammalian female gamete.
Qualifications
- PhD, University of Newcastle, 17/11/2006
- Bachelor of Science (Biotechnology)(Honours), University of Newcastle, 30/11/2001
Research
Research keywords
- Genetics
- Paediatrics
- Reproductive Medicine
Research expertise
- Egg quality and the ageing ovary
- Meiosis regulation in the female gamete
- Molecular mechanisms leading to aneuploidy in the egg
Fields of Research
| Code | Description | Percentage |
|---|
| 080200 | Computation Theory And Mathematics | 35 |
| 080600 | Information Systems | 35 |
| 111400 | Paediatrics And Reproductive Medicine | 30 |
EditPublications
No publications.
EditGrants and Funding
Summary
| Number of grants | 10 |
|---|
| Total funding | $905,573 |
|---|
For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.
- Indicates that the researcher may be seeking students for this project.
Click on a grant title below to expand the full details for that specific grant.
2013 (2 grants)
Leica TP 1020 Automatic Tissue Processor for histology applications$35,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team |
|---|
| Doctor Pradeep Tanwar, Professor Eileen McLaughlin, Professor Xu Dong Zhang, Professor Robert Callister, Associate Professor Phillip Dickson, Professor Hubert Hondermarck, Doctor Jean-Marie Sontag, Professor Dirk Van Helden, Doctor Doug Smith, Doctor Phil Jobling, Associate Professor Estelle Sontag, Associate Professor Paul Tooney, Doctor Susan Hua, Doctor Janet Holt, Doctor Jay Horvat, Associate Professor Liz Milward, Professor Adam McCluskey, Associate Professor Brett Nixon, Doctor Rebecca Lim, Associate Professor Alan Brichta |
| Scheme | Role |
|---|
| Equipment Grant | Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $35,000 | 2013 | 2013 |
| GNo:G1201185 |
The Annual Scientific Meeting of the Endocrine Society of Australia and Society of Reproductive Biology, Sydney 25-28 August 2013.$595
Funding Body: University of Newcastle - Faculty of Health
| Project Team |
|---|
| Doctor Janet Holt |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $595 | 2013 | 2013 |
| GNo:G1300895 |
2012 (2 grants)
Regulation of germ cell number and quality by Fizzy-Related protein$375,000
Funding Body: ARC (Australian Research Council)
| Project Team |
|---|
| Doctor Janet Holt |
| Scheme | Role |
|---|
| Discovery Early Career Researcher Award (DECRA) | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $375,000 | 2012 | 2015 |
| GNo:G1100556 |
The control of chromosome division during female meiosis$330,000
Funding Body: ARC (Australian Research Council)
| Project Team |
|---|
| Doctor Janet Holt |
| Scheme | Role |
|---|
| Discovery Projects | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $330,000 | 2012 | 2014 |
| GNo:G1100078 |
2011 (5 grants)
2010 Research Fellowship - PRCRS (DECRA 1/3/2012)$121,978
Funding Body: University of Newcastle
| Project Team |
|---|
| Doctor Janet Holt |
| Scheme | Role |
|---|
| Research Fellowship | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $121,978 | 2011 | 2013 |
| GNo:G1100163 |
Eppendorf mastercycler pro with thermomixer comfort and 5430R centrifuge$15,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team |
|---|
| Professor Eileen McLaughlin, Professor Peter Lewis, Professor Adam McCluskey, Conjoint Professor Keith Jones, Associate Professor Brett Nixon, Doctor Shaun Roman, Doctor Jennette Sakoff, Doctor Ian Grainge, Doctor Janet Holt, Doctor Xiao Yang |
| Scheme | Role |
|---|
| Equipment Grant | Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $15,000 | 2011 | 2011 |
| GNo:G1100028 |
Mechanisms underlying the incidence of aneuploidy in mammalian eggs$15,000
Funding Body: University of Newcastle
| Project Team |
|---|
| Doctor Janet Holt |
| Scheme | Role |
|---|
| Fellowship Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $15,000 | 2011 | 2011 |
| GNo:G1100395 |
IMPLEN NanoPhotometer pearl$10,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team |
|---|
| Doctor Murray Cairns, Associate Professor Paul Tooney, Associate Professor Alan Brichta, Professor John Rostas, Emeritus Professor Patricia Michie, Conjoint Professor Keith Jones, Professor Ulli Schall, Associate Professor Phillip Dickson, Doctor Frederick Walker, Doctor Rick Thorne, Doctor Chris Dayas, Doctor Nikki Verrills, Doctor Janet Holt, Doctor Severine Roselli, Doctor Kathryn Skelding, Doctor Jude Weidenhofer, Associate Professor Liz Milward, Doctor Charles De Bock, Doctor Julie Merriman-Jones, Doctor Jing Qin Wu, Doctor Bing Liu, Mr Dan Johnstone, Ms Belinda Goldie, Ms Natalie Beveridge |
| Scheme | Role |
|---|
| Equipment Grant | Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $10,000 | 2011 | 2011 |
| GNo:G1100030 |
EMBO Meiosis Meeting, Hotel Ariston and Congress Centre, Cappacio, Italy, 17 - 21 September 2011$1,500
Funding Body: University of Newcastle - Faculty of Health
| Project Team |
|---|
| Doctor Janet Holt |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $1,500 | 2011 | 2012 |
| GNo:G1100939 |
2010 (1 grants)
Cold Springs Harbor Germ Cell Conference, Cold Spring Harbor Laboratory, NT, USA, 5 - 9 October 2010$1,500
Funding Body: University of Newcastle - Faculty of Health
| Project Team |
|---|
| Doctor Janet Holt |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $1,500 | 2010 | 2011 |
| GNo:G1000768 |
EditResearch Supervision
| Number of current supervisions | 4 |
|---|
| Total current UoN PhD EFTSL | 1.1 |
|---|
For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.
Current Supervision
| Commenced | Proposed
Completion | Program | Supervisor Type | Research Title |
|---|
| 2013 | 2017 | PhD (Biological Sciences) | Co-Supervisor | The Impact of Maternal Ageing and Chemotoxicants on Female Fertility |
| 2013 | 2017 | PhD (Medical Biochemistry) | Co-Supervisor | Role of Stromal WNT Signaling in Ovarian Epithelial Carcinogenesis |
| 2013 | 2017 | PhD (Medical Genetics) | Co-Supervisor | To Investigate the Interaction of Breast Cancer and Ovarian Cancer |
| 2010 | 2014 | PhD (Human Physiology) | Principal Supervisor | Elucidation of Higher Meiotic Errors on Oocyte from Advanced Maternat Ages through Kinetochore Tracking |
Past Supervision
| Year | Program | Supervisor Type | Research Title |
|---|
| 2013 | PhD (Human Physiology) | Co-Supervisor | Role of Fzr1 in Embryogenesis |
| 2012 | M Philosophy (Human Physiolog) | Co-Supervisor | Characterisation of an Oocyte Specific Knockout Model of Cdh1 |
| 2012 | PhD (Human Physiology) | Co-Supervisor | Control of Chromosome Segregation in Mouse Oocytes |
