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Career Summary

Biography

Having trained in Paediatrics in the U.K., I sub-specialised in neonatal medicine. I have a strong background in academic neonatal medicine, undertaking my research training with Professor Malcolm Levene in Leeds. I have experience at a senior level in major teaching hospitals in the UK, New Zealand and Australia, holding specialist qualifications in both the U.K. and Australia. I have been involved at these sites in the running of research studies ranging from physiology studies through to international multi-centred trials and thus have extensive experience of the difficulties of recruitment and involvement of sick neonates in clinical trials. Most of my research has examined aspects of cardiovascular function in neonates. In particular I have experience of a variety of vascular flow methods, including Ultrasonic Doppler, laser Doppler, flow probes (in animals) and xenon cerebral blood flow. I continued my interest in neonatal cardiovascular adaptation through my time as Neonatal Senior Lecturer in Auckland and to my current post in Newcastle.

I am now a part of the Mothers and Babies Research Centre of the Hunter Medical Research Institute, directed by Professor Roger Smith and I have developed the project on the effect of gender on neonatal cardiovascular adaptation with Dr Vicki Clifton. This work has been developed from work that we have done looking at the mechanisms of microvascular control in pregnancy and the effects of preeclampsia. I have been responsible for the microvascular part of these studies. Local competitive grants and an equipment grant from local industry (2000-4) have funded this work, which has recently been performed as part of the PhD of Dr Michael Stark and has lead to international recognition, prize awards and several publications.

I work 50% of my time as a Senior Staff Specialist Neonatologist and as 50% as Senior lecturer the Faculty of Health of the University of Newcastle. Research is an integral part of that work and I am currently undertaking a self-funded PhD. I have recently supervised 1 PhD student, and 2 honours students and two summer studentships, all awarded on time. I currently supervise 2 PhD students. I am actively involved in encouraging research participation by junior medical, nursing and allied health staff. I am the convenor of the ABC Children’s Research network – a group of over 100 children’s researchers in NSW. I am the paediatric representative on the Research Council of the Hunter Medical Research Institute.

I am currently or have recently been local coordinator for several national and international studies aimed at improving outcomes for the sick or preterm infant including: the ICE trial (NHMRC ID:216725), BOOST2 (NHMRC ID: 352386), the Proprems trial and I was an Associate Investigator on The Bubbles for Babies trial of level 2 CPAP (NHMRC ID:253790) and DAISY trial of developmental outcomes of surgical infants (March of Dimes, US,). I am a PI on the TORPIDO study of oxygen targeting in the preterm and on the PremiRemi trial. I currently am sole CI on NHMRC grant 569285 2009-2013.

Qualifications

  • Bachelor of Medicine, Bachelor of Surgery, University of Newcastle upon Tyne - England

Research

Research keywords

  • Cardiovascular
  • Fetal Development
  • Microvascular
  • Neonatal Intensive Care
  • Neonatal Survival
  • Neonate
  • Paediatrics
  • Reproductive Medicine
  • Sex Differences

Research expertise

Ian is a Senior Staff Specialist in neonatal medicine within the John Hunter Children's Hospital and Associate Professor in Paediatrics and Child Health, Newcastle University. Ian's own research program is focused on cardiovascular adaptation of newborns following preterm birth, for which he holds a sole investigator NHMRC grant and has a developing research group. He leads the Newcastle Neonatal Research Group, within the Mother and Babies Research Centre of HMRI. Ian is currently local coordinator, AI or CI for several national and international studies aimed at improving outcomes for sick or preterm infants

Fields of Research

CodeDescriptionPercentage
110399Clinical Sciences Not Elsewhere Classified45
111403Paediatrics45
110299Cardiovascular Medicine And Haematology Not Elsewhere Classified10

Collaboration

Dr Hannah Palliser and Ms Rebecca Dyson, University of Newcastle (2010-ongoing): This project focuses on microvascular function in the preterm neonate and uses the guinea pig as an animal model for preterm birth. Two years of local funding has been awarded for this research, which supports the work of 1 PhD student and 1 honours student. One publication has been accepted and 9 conference abstracts have been presented on this work.

Dr Yoga Kandasamy, Townsville Hospital (2009-ongoing): This collaboration is exploring the relationship between kidney size and function in preterm babies and relating this to the appearance of the blood vessels in the retina. It is hoped this research will increase our insight into the risk of chronic renal failure as premature infants grow.

Dr. Barbara Lingwood (University of Queensland) and Em Prof Eugine Lumbers (University New South Wales): Newborn Pigs are being used to explore the cardiovascular adaptation of preterm neonates. The research combines expertise in heart structure and control along with expertise in microvascular blood flow.

Dr Susie Lord, Alison Jones and Kate O’Hara (University of Newcastle): A collaboration focusing on neonatal pharmacology. In particular, this collaboration looks at the use of remifentanil; a fast acting, short lived opioid; in neonates for pain relief during intensive care procedures.

Associate Professor Vicki Clifton, Dr Michael Stark and Dr Nicolette Hodyl (University of Adelaide): The collaborators within this group provide expertise in placental physiology, fetal growth, neonatal adaptation and neonatal immune development. This collaboration has recently resulted in a publication on the the Influence of fetal sex and antenatal betamethasone exposure on the preterm microvasculature.

Current clinical trials:

Boost II (University of Sydney): Very premature babies may need treatment with oxygen because their lungs are not fully developed but a premature baby's eyes, lungs or brain can be harmed by too much or too little oxygen in the blood for long periods. The purpose of this study is to understand which blood oxygen level (oxygen saturation) is better for very premature babies.

TORPIDO (University of New South Wales): When babies are born they may need some oxygen to help them recover from the birth process. We have switched from using 100% oxygen for all babies to using air and increasing oxygen as required in term babies as this has been shown to improve their outcomes. This study is looking to see if we should be doing the same thing or continue with 100% oxygen in premature babies at delivery.

Australian Placental Transfusion Study (APTS) (North Shore Heart Research Foundation): This trial is testing the benefits of a placental transfusion at birth on cardiac function and outcome in preterm infants. It involves delaying the clamping of the umbilical cord for up the 60 seconds.

AEEG (Murdoch Children's Research Institute): Seizures in the newborn infant are common and may be harmful to the developing brain. They are not always recognised. This study investigates whether or not treating all seizures detected using a bedside brain activity monitor improves developmental outcome, compared to just treating seizures that doctors recognise.

High-flow nasal cannulae trial (HFNC): A multicentre, randomised controlled trial (University of Newcastle): This study aims to answer the question of whether High Flow Nasal Cannulae (HFNC), a gentle, easy-to-use new way of providing support for babies with breathing diificulties, can be used in special care nurseries to significantly reduce the number of babies who need transfer to a neonatal intensive care unit (NICU) 100s kms away.

Administrative

Administrative expertise

Consultant neonatal senior staff specialist

Chair of research subcommittee of Hunter Children’s Research Executive

HMRI representation on NSW Paediatric Research Network Committee

Course Coordinator for B Med Sci University of Newcastle.

200-2004 Treasurer of Hunter Paediatric Society

HMRI representation on National Paediatric Research Network Committee

Convenor of ABC Children's Research Network

Teaching

Teaching keywords

  • Fetal Development
  • Neonatal Intensive Care
  • Neonatal Survival
  • Neonate
  • Paediatrics
  • Reproductive Medicine

Teaching expertise

Undergraduate:

Tutor University of Manchester; organising curriculum delivery, monitoring teaching, individual student supervision, as well as organising OSCE examination for the entire year (200+ students)

Research fellow Leeds University; Curriculum delivery through individual student tutoring, small group seminars and assessment through MCQ and OSCE examination at both St James's University Hospital and Leeds Infirmary.

Senior Lecturer in Neonatology, University of Auckland; Undergraduate curriculum delivery for 4th yr medical students. Elective research student supervision.

University of Newcastle; Organisation of neonatal component of 4th year undergraduate paediatric curriculum. Collegiate development of the paediatric curriculum over the years (only conjoint to regularly attend discipline meetings for past 10 years). Teaching into Biomedical Science, Nursing, Medicine, Education and Sports Sciences. Supervision of research attachments and elective projects for Biomedical, Biotech, Psychology and Medical students, University of Newcastle and overseas elective students (approx 4 student projects supervised per year, excluding overseas). Exam duties (questions written, reviewed and marked, summative projects, clinical exams and OSCE).

Postgraduate:

Informal teaching on a regular basis for clinical MRCP (past) and FRACP (current) candidates.

Specialist neonatal nursing and Neonatal Nurse Practioner courses at Leeds, Auckland and Newcastle.

PBL training and delivery, University of Newcastle.

‘Teaching on the Run’ course as participant and then teacher.

Neonatal Advanced Life Support workshops on regular basis.

Introduction of regular performance appraisal tools for basic and advance trainees in NICU (prior to RACP recommendation).

Introduction of Minicex assessment for basic and advance trainees in NICU (prior to RACP recommendation).

AMC work based assessments for the past 2 years

Successful supervision of PhD candidature of Dr Michael Stark and 2 previous research honours students. 3 further current PhD students (on track) and another commencing 2012.

I have an increasing interest in the methodology of assessment examined at undergraduate level in 3 countries and continue to do so locally. I have set questions for and examined for the Diploma in Obstetrics for the Royal College of Obstetrics and Gynaecology of Australia and New Zealand and have examined for the national postgraduate FRACP clinical exam.

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Highlighted Publications

For publications that are currently unpublished or in-press, details are shown in italics.

YearCitationAltmetricsLink
2009Stark MJ, Clifton VL, Wright IM, 'Neonates born to mothers with preeclampsia exhibit sex-specific alterations in microvascular function', Pediatric Research, 65 291-295 (2009) [C1]
2009Stark MJ, Clifton VL, Wright IM, 'Carbon monoxide is a significant mediator of cardiovascular status following preterm birth', Pediatrics, 124 277-284 (2009) [C1]
2008Stark MJ, Clifton VL, Wright IM, 'Microvascular flow, clinical illness severity and cardiovascular function in the preterm infant', Archives of Disease in Childhood Fetal & Neonatal Edition, 93 F271-F274 (2008) [C1]
2007Buckmaster AG, Arnolda G, Wright IM, Henderson-Smart DJ, 'The use of CPAP to reduce up transfer of infants with respiratory distress in non-tertiary care centres: A randomised controlled trial', Journal of Paediatrics and Child Health, Melbourne, VIC (2007) [E3]

This research changed practise at a national level

Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (1 outputs)

YearCitationAltmetricsLink
2012Hure AJ, Wright IM, 'Obesity in pregnancy: Implications for foetal and postnatal growth', Handbook of Growth and Growth Monitoring in Health and Disease, Springer, New York 221-234 (2012) [B1]

Co-authors: Alexis Hure

Journal article (50 outputs)

YearCitationAltmetricsLink
2014Dyson RM, Palliser HK, Latter JL, Chwatko G, Glowacki R, Wright IMR, 'A Role for H2S in the microcirculation of newborns: The major metabolite of H2S (thiosulphate) is increased in preterm infants', PLoS ONE, 9 (2014) [C1]
2014Kandasamy Y, Smith R, Wright IMR, Lumbers ER, 'Reduced nephron endowment in the neonates of Indigenous Australian peoples', JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE, 5 31-35 (2014)
2013Kandasamy Y, Smith R, Wright IMR, Lumbers ER, 'Relationships between glomerular filtration rate and kidney volume in low-birth-weight neonates', JOURNAL OF NEPHROLOGY, 26 894-898 (2013) [C1]
2013Kandasamy Y, Smith R, Wright I, Hartley L, 'Use of digital retinal imaging in screening for retinopathy of prematurity', JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 49 E1-E5 (2013) [C1]
2013Kandasamy Y, Smith R, Wright IMR, 'Relationship between the Retinal Microvasculature and Renal Volume in Low-Birth-Weight Babies', AMERICAN JOURNAL OF PERINATOLOGY, 30 477-481 (2013) [C1]
2013Kandasamy Y, Smith R, Wright IMR, 'Measuring Cystatin C to Determine Renal Function in Neonates', PEDIATRIC CRITICAL CARE MEDICINE, 14 318-322 (2013) [C1]
2013Kandasamy Y, Smith R, Wright IMR, Lumbers ER, 'Extra-uterine renal growth in preterm infants: Oligonephropathy and prematurity', PEDIATRIC NEPHROLOGY, 28 1791-1796 (2013) [C1]
2013Collins CE, Burrows TL, Truby H, Morgan PJ, Wright IMR, Davies PSW, Callister R, 'Comparison of Energy Intake in Toddlers Assessed by Food Frequency Questionnaire and Total Energy Expenditure Measured by the Doubly Labeled Water Method', Journal of the Academy of Nutrition and Dietetics, 113 459-463 (2013) [C1]
2013Hosking SPM, Bhatia R, Crock PA, Wright I, Squance ML, Reeves G, 'Non-invasive detection of microvascular changes in a paediatric and adolescent population with type 1 diabetes: A pilot cross-sectional study', BMC Endocrine Disorders, 13 (2013) [C1]
2012Kandasamy Y, Smith R, Wright IM, 'Retinal microvascular changes in low-birth-weight babies have a link to future health', Journal of Perinatal Medicine, 40 209-214 (2012) [C1]

Co-authors: Roger Smith

2012Kandasamy Y, Smith R, Wright IM, Hartley L, 'Relationship between birth weight and retinal microvasculature in newborn infants', Journal of Perinatology, 32 443-447 (2012) [C1]

Co-authors: Roger Smith

2012Kandasamy Y, Smith R, Wright IM, 'Oligonephropathy of prematurity', American Journal of Perinatology, 29 115-120 (2012) [C1]

Co-authors: Roger Smith

2012Buckmaster AG, Arnolda G, Wright IM, Foster J, 'Targeted oxygen therapy in special care nurseries: Is uniformity a good thing?', Journal of Paediatrics and Child Health, 48 476-482 (2012) [C1]
2012Koh J, Yeo CL, Wright IM, Lui K, Saugstad O, Tarnow-Mordi W, et al., 'The use of oxygen for delivery room resuscitation of newborn infants in non-Western countries', Early Human Development, 88 631-635 (2012) [C1]
2012Kent AL, Wright IM, Abdel-Latif ME, 'Mortality and adverse neurologic outcomes are greater in preterm male infants', Pediatrics, 129 124-131 (2012) [C1]
2012Dyson RM, Palliser HK, Kelleher MA, Hirst JJ, Wright IM, 'The guinea pig as an animal model for studying perinatal changes in microvascular function', Pediatric Research, 71 20-24 (2012) [C1]
2012Kandasamy Y, Smith R, Wright IM, Hartley L, 'Optic disc measurements in full term infants', British Journal of Ophthalmology, 96 662-664 (2012) [C1]

Co-authors: Roger Smith

2012Clifton VL, Davies M, Moore V, Wright IM, Ali Z, Hodyl NA, 'Developmental perturbation induced by maternal asthma during pregnancy: The short- and long-term impacts on offspring', Journal of Pregnancy, 2012 1-8 (2012) [C1]
2012Hure AJ, Collins CE, Giles WB, Wright IM, Smith R, 'Protocol for the Women and Their Children's Health (WATCH) Study: A cohort of pregnancy and beyond', Journal of Epidemiology, 22 267-275 (2012) [C3]
2011Jacobs SE, Morley CJ, Inder TE, Stewart MJ, Smith KR, McNamara PJ, et al., 'Whole-body hypothermia for term and near-term newborns with hypoxic-ischemic encephalopathy: A randomized controlled trial', Archives of Pediatrics & Adolescent Medicine, 165 692-700 (2011) [C1]
2011Kandasamy Y, Smith R, Wright IM, 'Retinal microvasculature measurements in full-term newborn infants', Microvascular Research, 82 381-384 (2011) [C1]

Co-authors: Roger Smith

2011Jones LJ, Craven P, Attia JR, Thakkinstian A, Wright IM, 'Network meta-analysis of indomethacin versus ibuprofen versus placebo for PDA in preterm infants', Archives of Disease in Childhood-Fetal and Neonatal Edition, 96 F45-F52 (2011) [C1]
2011Kandasamy Y, Smith R, Wright IM, Hartley L, 'Pain relief for premature infants during ophthalmology assessment', Journal of AAPOS, 15 276-280 (2011) [C1]

Co-authors: Roger Smith

2011Stark MJ, Hodyl NA, Wright IM, Clifton VL, 'Influence of sex and glucocorticoid exposure on preterm placental pro-oxidant-antioxidant balance', Placenta, 32 865-870 (2011) [C1]
2011Stark MJ, Hodyl NA, Wright IM, Clifton V, 'The influence of sex and antenatal betamethasone exposure on vasoconstrictors and the preterm microvasculature', Journal of Maternal-Fetal & Neonatal Medicine, 24 1215-1220 (2011) [C1]
2011Jacobs SE, Morley CJ, Inder TE, Stewart MJ, Smith KR, McNamara PJ, et al., 'Whole-Body Hypothermia for Term and Near-Term Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Controlled Trial EDITORIAL COMMENT', OBSTETRICAL & GYNECOLOGICAL SURVEY, 66 743-744 (2011) [C3]
2010Kapoor V, Wright IM, 'Congenital myotonic dystrophy with cardiac conduction defect and eventration of the diaphragm', Pediatrics International, 52 E6-E8 (2010) [C1]
2010Giles M, Parker VT, Bevan H, Wright IM, 'Comparing Point of Care International Normalised Ratio testing with laboratory testing methods in a cardiac inpatient population', Journal of Clinical Nursing, 19 3085-3091 (2010) [C1]
2009Stark MJ, Wright IM, Clifton VL, 'Sex-specific alterations in placental 11 beta-hydroxysteroid dehydrogenase 2 activity and early postnatal clinical course following antenatal betamethasone', American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 297 R510-R514 (2009) [C1]
2009Stark MJ, Clifton VL, Wright IM, 'Neonates born to mothers with preeclampsia exhibit sex-specific alterations in microvascular function', Pediatric Research, 65 291-295 (2009) [C1]
2009Stark MJ, Clifton VL, Wright IM, 'Carbon monoxide is a significant mediator of cardiovascular status following preterm birth', Pediatrics, 124 277-284 (2009) [C1]
2009Wright IM, Wake CH, Anderson H, Graham S, 'Assessment of the multidisciplinary education for a major change in clinical practice: A prospective cohort study', BMC Health Services Research, 9 28 (1-6) (2009) [C1]
2009Vu TT, Hirst JJ, Stark MJ, Wright IM, Palliser HK, Hodyl NA, Clifton VL, 'Changes in human placental 5 alpha-reductase isoenzyme expression with advancing gestation: Effects of fetal sex and glucocorticoid exposure', Reproduction Fertility and Development, 21 599-607 (2009) [C1]
2009Wright IM, Wagner M, Owers M, 'A new formula for umbilical arterial catheterization in very low-birth weight infants: Reply', Pediatric Critical Care Medicine, 10 422 (2009) [C3]
2008Amey M, Butchard N, Hanson L, Kinross D, Mannion M, Parsons J, Wright IM, 'Cautionary tales from the neonatal intensive care unit: Diapers may mislead urinary output estimation in extremely low birthweight infants', Pediatric Critical Care Medicine, 9 76-79 (2008) [C1]
2008Ling SK, Wooderson S, Rees K, Neild R, Wright IM, 'A smoking cessation program in the neonatal intensive care unit', Journal of Smoking Cessation, 3 73-76 (2008) [C1]
2008Meyer S, Todd D, Wright IM, Gortner L, Reynolds G, 'Review article: Non-invasive assessment of cardiac output with portable continuous-wave Doppler ultrasound', Emergency Medicine Australasia: EMA, 20 201-208 (2008) [C1]
2008Wright IM, Owers M, Wagner M, 'The umbilical arterial catheter: A formula for improved positioning in the very low birth weight infant', Pediatric Critical Care Medicine, 9 498-501 (2008) [C1]
2008Stark MJ, Clifton VL, Wright IM, 'Sex-specific differences in peripheral microvascular blood flow in preterm infants', Pediatric Research, 63 415-419 (2008) [C1]
2008Stark MJ, Clifton VL, Wright IM, 'Microvascular flow, clinical illness severity and cardiovascular function in the preterm infant', Archives of Disease in Childhood Fetal & Neonatal Edition, 93 F271-F274 (2008) [C1]
2007Buckmaster AG, Arnolda G, Wright IM, Foster JP, Henderson-Smart DJ, 'Continuous positive airway pressure therapy for infants with respiratory distress in non-tertiary care centers: A randomized, controlled trial', Pediatrics, 120 509-518 (2007) [C1]
2007Buckmaster AG, Buckmaster AG, Wright IM, Henderson-Smart DJ, 'CPAP use in babies with respiratory distress in Australian special care nurseries', Journal of Paediatrics and Child Health, 43 376-382 (2007) [C1]
2007Buckmaster AG, Wright IM, Arnolda G, Henderson-Smart DJ, 'Practice variation in initial management and transfer thresholds for infants with respiratory distress in Australian hospitals. Who should write the guidelines?', Journal of Paediatrics and Child Health, 43 469-475 (2007) [C1]
2007McKenzie F, Fietz M, Fletcher J, Smith RL, Wright IM, Jaeken J, 'A previously undescribed form of congenital disorder of glycosylation with variable presentation in siblings: Early fetal loss with hydrops fetalis, and infant death with hypoproteinemia', American Journal of Medical Genetics, Part A, 143 2029-2034 (2007) [C3]
2006Henderson-Smart DJ, Hutchinson JL, Donoghue DA, Evans NJ, Simpson JM, Wright IM, 'Prenatal predictors of chronic lung disease in very preterm infants', Archives of Disease in Childhood-Fetal and Neonatal Edition, 91 F40-F45 (2006) [C1]
2006Stark MJ, Dierkx LM, Clifton VL, Wright IM, 'Alterations in the Maternal Peripheral Microvascular Response in Pregnancies Complicated by Preeclampsia and the Impact of Fetal Sex', Journal of the Society for Gynecologic Investigation, 13 573-578 (2006) [C1]
2005Clifton VL, Crompton R, Read MA, Gibson PG, Smith R, Wright IM, 'Microvascular Effects of Corticotropin-Releasing Hormone in Human Skin Vary in Relation to Estrogen Concentration During the Menstrual Cycle', Journal of Endocrinology, 186 69-76 (2005) [C1]
2003Crompton R, Clifton VL, Bisits AM, Read MA, Smith R, Wright IM, 'Corticotropin-releasing hormone causes vasodilation in human skin via mast cell-dependent pathways', Journal Of Clinical Endocrinology And Metabolism, 88 5427-5432 (2003) [C1]
2002Clifton VL, Crompton R, Smith R, Wright ML, 'Microvascular Effects of CRH in Human Skin Vary in Relation to Gender', The Journal of Clinical Endocrinology & Metabolism, 87(1) 267-270 (2002) [C1]
1999Wright IMR, 'Neonatal effects of maternal consumption of blue cohosh', JOURNAL OF PEDIATRICS, 134 384-384 (1999)
Show 47 more

Conference (55 outputs)

YearCitationAltmetricsLink
2012Wright IM, Latter JL, Wright A, Finnegan T, Clifton VL, 'Maternal peripheral constriction in preeclampsia is not reflected in the central microvasculature', Journal of Paediatrics and Child Health, Sydney, Australia (2012) [E3]

Co-authors: Vicki Clifton

2012Koh J, Yeo CL, Wright IM, Lui K, Saugstad OD, Tarnow-Mordi W, Oei J, 'The use of oxygen for the delivery room resuscitation of newborn infants in non-western countries', Journal of Paediatrics and Child Health, Sydney, Australia (2012) [E3]
2012Shepherd K, Palliser HK, Dyson RM, Wright IM, 'Regulation of microvascular blood fow by heme oxygenase in the preterm neonate', Proceedings of the 39th Annual Meeting of the Fetal and Neonatal Physiological Society, Zeist, The Netherlands (2012) [E3]

Co-authors: Hannah Palliser

2012Collins CE, Burrows TL, Truby H, Wright IM, Morgan PJ, Davies P, Callister R, 'Doubly labelled water validation of toddler total energy intake assessed by a food frequency questionnaire', 8th International Conference on Diet and Activity Methods (ICDAM 8). Abstract Book, Rome, Italy (2012) [E3]
2012Wright IM, Latter JL, Buchan J, 'Videomicroscopy of neonatal microvasculature: Relationship to laser doppler flowmetry', Proceedings of the 39th Annual Meeting of the Fetal and Neonatal Physiological Society, Zeist, The Netherlands (2012) [E3]
2012Kandasamy Y, Smith R, Wright IM, 'The relationship between birthweight and retinal microvasculature in term infants', Journal of Paediatrics and Child Health, Sydney, Australia (2012) [E3]

Co-authors: Roger Smith

2012Dyson RM, Palliser HK, Latter JL, Chwatko G, Glowacki R, Wright IM, 'Hydrogen sulphide in the neonatal transitional circulation', Proceedings of the 39th Annual Meeting of the Fetal and Neonatal Physiological Society, Zeist, The Netherlands (2012) [E3]

Co-authors: Hannah Palliser

2012Khan A, Wright IM, 'Simulation for postgraduate multi-professional neonatal resuscitation education', Symposium Program. Interprofessional Education for Quality Use of Medicines, Newcastle Beach, NSW (2012) [E3]
2012Wright IM, Latter JL, Wright A, Finnegan T, Clifton VL, 'Functional capillary density in babies born to mothers with preeclampsia', 16th Annual Congress of the Perinatal Society of Australia and New Zealand, Sydney, NSW (2012) [E3]

Co-authors: Vicki Clifton

2011Dyson RM, Palliser HK, Wright IM, 'Dysregulated microvascular flow in early extrauterine life in the pretern guinea pig', Journal of Paediatrics and Child Health, Hobart, Tasmania (2011) [E3]

Co-authors: Hannah Palliser

2011Dyson RM, Palliser HK, Wright IM, 'Early microvascular blood flow changes: Evidence from human and guinea pig neonates', XIX NSW Scientific Meeting. Programme, Sydney, NSW (2011) [E3]

Co-authors: Hannah Palliser

2011Wright IM, Dyson RM, Latter JL, Clifton VL, 'Microvascular blood flow changes from 6 to 24 h in the preterm infant', Journal of Paediatrics and Child Health, Hobart, Tasmania (2011) [E3]

Co-authors: Vicki Clifton

2011Dyson RM, Palliser HK, Wright IM, 'H2S; A novel player in the transitional microcirculation of preterm neonates?', Proceedings of The 38th Meeting of The Fetal and Neonatal Physiological Society, Palm Cove, QLD (2011) [E3]

Co-authors: Hannah Palliser

2011Lakkundi AK, Wright IM, De Waal K, 'Haemodynamic effects of prophylactic surfactant replacement therapy with rapid extubation to nasal CPAP', Journal of Paediatrics and Child Health, Hobart, Tasmania (2011) [E3]
2011Hure AJ, Lorien S, Griffis D, Wright IM, 'Potential for high magnesium intakes from infant formula made up using bottled water', PSANZ 2011 15th Annual Congress: Poster Abstracts, Hobart, TAS (2011) [E3]

Co-authors: Alexis Hure

2011Kent AL, Wright IM, Abdel-Latif ME, Neonatal Intensive Care Units Audit Group, 'Is it still a disadvantage to be born male and extremely preterm in Australia?', Journal of Paediatrics and Child Health, Hobart, Tasmania (2011) [E3]
2011Lutz T, Buckmaster AG, Kluckow M, Wright IM, Bowen J, 'Need for neonatal intensive care (NIC) for babies 29 to 34 weeks gestation', Journal of Paediatrics and Child Health, Hobart, Tasmania (2011) [E3]
2010Jacobs SE, Stewart M, McNamara P, Wright IM, Kirpalani H, Darlow B, et al., ''Ice' safety of whole body cooling for hypoxicischaemic encephalopathy (HIE) during neonatal retrieval', Journal of Paediatrics and Child Health: Abstracts of the 14th Annual Congress of the Perinatal Society of Australia and New Zealand 2010, Wellington, NZ (2010) [E3]
2010Buckmaster AG, Arnolda G, Foster J, Wright IM, 'Oxygen therapy in special care nurseries. Is uniformity a good thing?', Journal of Paediatrics and Child Health: Abstracts of the 14th Annual Congress of the Perinatal Society of Australia and New Zealand 2010, Wellington, NZ (2010) [E3]
2010Dyson RM, Kelleher MA, Palliser HK, Wright IM, 'The guinea pig as an animal model for perinatal vascular changes?', Journal of Paediatrics and Child Health: Abstracts of the 14th Annual Congress of the Perinatal Society of Australia and New Zealand 2010, Wellington, NZ (2010) [E3]

Co-authors: Hannah Palliser

2010Jacobs SE, Stewart M, McNamara P, Wright IM, Kirpalani H, Darlow B, et al., 'The 'ice' randomised trial of whole body cooling for hypoxic-ischaemic encephalopathy (HIE)', Journal of Paediatrics and Child Health: Abstracts of the 14th Annual Congress of the Perinatal Society of Australia and New Zealand 2010, Wellington, NZ (2010) [E3]
2010Dyson RM, Kelleher MA, Palliser HK, Hirst JJ, Wright IM, 'The guinea pig as an animal model for studying microvascular function in the preterm neonate in early extrauterine life', 9th World Congress for Microcirculation. Final Program and Abstract Book, Paris, France (2010) [E3]
2010Hure AJ, Wright IM, Smith R, Collins CE, 'Evidence-based best-practice guidelines for nutritional supplementation in pregnancy', Nutrition & Dietetics, Melbourne (2010) [E3]
2010Wright IM, Latter JL, Finnegan T, Clifton VL, 'Placental vascular mediators in preeclampsia', Journal of Paediatrics and Child Health: Abstracts of the 14th Annual Congress of the Perinatal Society of Australia and New Zealand 2010, Wellington, NZ (2010) [E3]

Co-authors: Vicki Clifton

2010Dyson RM, Palliser HK, Kelleher MA, Hirst JJ, Wright IM, 'Preterm birth and intrauterine growth restriction: effect of microvascular function in the neonatal guinea pig', The Endocrine Society of Australia Annual Scientific Meeting Proceedings and Abstract Book, Sydney (2010) [E3]
2009Jones LJ, Craven PD, Attia JR, Thakkinstian A, Wright IM, 'Administration of intravenous ibuprofen for significant PDA in preterm infants at greater than 24 h of life: Does it increase the risk of chronic lung disease (CLD)?', Journal of Paediatrics and Child Health, Darwin, NT (2009) [E3]
2009Knox M, Smith R, Engel T, Wright IM, 'Transfers into a regional perinatal centre: Can we do better?', Journal of Paediatrics and Child Health, Darwin, NT (2009) [E3]
2009Hure AJ, Wright IM, Smith R, Collins CE, 'Nutrient supplementation in pregnancy: Development of evidence-based best-practice guidelines', Journal of Paediatrics and Child Health, Darwin, NT (2009) [E3]
2009Wright IM, Smith AJ, Clifton VL, Stark MJ, 'Nappy urine collection for physiological measures: A current method', Journal of Paediatrics and Child Health, Darwin, NT (2009) [E3]
2009Hure AJ, Wright IM, Smith R, Collins CE, 'Nutrient supplementation in pregnancy: Development of evidence-based best-practice guidelines', Journal of Developmental Origins of Health and Disease, Santiago, Chile (2009) [E3]
2008Wright IM, Clifton VL, 'Microvascular orthogonal polarisation spectral imaging videomicroscopy (OPS) in mother and newborn using a handheld microscope: Technical pitfalls and solutions', Journal of Paediatrics and Child Health, Gold Coast, QLD (2008) [E3]
2008Stark MJ, Clifton VL, Wright IM, 'Predictors of microvascular blood flow in very preterm infants at 24 hours of age', Journal of Paediatrics and Child Health, Gold Coast, QLD (2008) [E3]
2008Stark MJ, Clifton VL, Wright IM, 'Sex-specific differences in circulating carbon monoxide and the increased incidence of hypotension in male preterm infants', Archives of Disease in Childhood: Fetal and Neonatal Edition, Harrogate, UK (2008) [E3]

Co-authors: Vicki Clifton

2008Giles M, Bevan H, Walters J, Heads J, Wright IM, Parker VT, 'Point of care international normalised ratio testing in acute cardiac wards', Heart, Lung and Circulation, Melbourne, VIC (2008) [E3]
2008Stark MJ, Wright IM, Clifton VL, 'Antenatal betamethasone exerts sexually dimorphic effects on placental glucocorticoid metabolism and fetal and neonatal adrenal function following preterm birth', Archives of Disease in Childhood: Fetal and Neonatal Edition, Harrogate, UK (2008) [E3]

Co-authors: Vicki Clifton

2008Stark MJ, Clifton VL, Wright IM, 'The influence of sex and antenatal glucocorticoid exposure on microvascular vasodilatory capacity in the preterm infant', Journal of Paediatrics and Child Health, Gold Coast, QLD (2008) [E3]
2008Cruden L, Kent-Biggs J, Black R, Wake C, Wright IM, 'Is there a shift in practice? A review of gastroschisis at the JHCH NSW', Journal of Paediatrics and Child Health, Gold Coast, QLD (2008) [E3]
2007Stark MJ, Clifton VL, Wright IM, 'Sex specific differences peripheral microvascular blood flow are a marker of clinical illness severity in the preterm infant', Journal of Paediatrics and Child Health, Melbourne (2007) [E3]

Co-authors: Vicki Clifton

2007Stark MJ, Wright IM, Clifton VL, 'Placental 11b-hydroxysteroid dehydrogenase 2 activity in preterm pregnancy after antenatal betamethasone treatment', Journal of Paediatrics and Child Health, Melbourne (2007) [E3]

Co-authors: Vicki Clifton

2007Talbot PI, Wright IM, Hilton JM, Mattes J, Clifton VL, 'Effect of maternal asthma during pregnancy on childhood growth and development of atopic disease', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]
2007Scott NM, Stark MJ, Wright IM, Hodgson DM, Smith R, Clifton VL, 'Placental inflammatory response in pregnancies complicated by preterm delivery or asthma', Journal of Paediatrics and Child Health, Melbourne (2007) [E3]
2007Stark MJ, Clifton VL, Wright IM, 'Sexually dimorphic differences in microvascular function influence physiological stability following premature birth', Microcirculation, Milwaukee, Wisc. (2007) [E3]

Co-authors: Vicki Clifton

2007Scott NM, Stark MJ, Wright IM, Hodgson DM, Smith R, Clifton VL, 'Response of placental explants from term and preterm pregnancies to an immune challenge', Reproductive Sciences (Scientific Program & Abstracts: 54th Annual Meeting, SGI), Reno, Nevada (2007) [E3]
2007Hodyl NA, Stark MJ, Clifton VL, Wright IM, 'Pre-eclampsia affects incidence of infants born small for gestational age differentially depending on both infant sex and degree of prematurity', Endocrine Journal, Christchurch, New Zealand (2007) [E3]

Co-authors: Vicki Clifton

2007Stark MJ, Wright IM, Clifton VL, 'Temporal changes in mediators of microvascular tone are influences by sex and glucocorticoid exposure in preterm infants', Satellite Conference of DOHaD 2007 (5th World Congress of Developmental Origins of Health and Disease), Melbourne, VIC (2007) [E3]

Co-authors: Vicki Clifton

2007Clifton VL, Mayhew TM, Wright IM, Stark MJ, Giles WB, 'The effects of pre-eclampsia, asthma and fetal sex on maternal, fetal and neonatal characteristics', Placenta, Kingston, Ontario (2007) [E3]

Co-authors: Vicki Clifton

2007Buckmaster AG, Arnolda G, Wright IM, Henderson-Smart DJ, 'The use of CPAP to reduce up transfer of infants with respiratory distress in non-tertiary care centres: A randomised controlled trial', Journal of Paediatrics and Child Health, Melbourne, VIC (2007) [E3]

This research changed practise at a national level

2007Stark MJ, Wright IM, Clifton VL, 'Placental 11b hydroxysteroid dehydrogenase 2 and regulation of fetal adrenal function: The influence of exogenouse gluco-corticoids and fetal sex in normal and growth restricted infants', Fetal & Neonatal Workshop of Australia and New Zealand 21st Annual Meeting. Abstracts, Melbourne, VIC (2007) [E3]

Co-authors: Vicki Clifton

2007Vootakuru L, Wake CH, Wright IM, 'Use of a higher treatment assessment threshold on modified finnigan scoring for neonatal abstinence syndrome', Journal of Paediatrics and Child Health, Melbourne, VIC (2007) [E3]
2007Stark MJ, Hodyl NA, Wright IM, Clifton VL, 'Determinants of fetal growth following assisted conception: Effects of early onset pre-eclampsia', Early Human Development, Perth, W. A. (2007) [E3]

Co-authors: Vicki Clifton

2006Scott NM, Stark MJ, Wright IM, Hodgson DM, Smith R, Clifton VL, 'Differences in tumour mecrosis factor alpha production by term and preterm placentae', Endocrine Journal-Continuation of Endocrinologia Japonica, Queensland, Australia (2006) [E3]
2006Stark MJ, Wright IM, Clifton VL, 'The impact of antenatal corticosteroids on umbilical venous and arterial cortisol in neonates 23-41 weeks gestation', Endocrine Journal-Continuation of Endocrinologia Japonica, Queensland, Australia (2006) [E3]

Co-authors: Vicki Clifton

2006Stark MJ, Wright IM, Clifton VL, 'Maternal microvascular response to corticotrophin releasing hormone (CRH) is altered by gestation, fetal gender and pre-eclampsia (Poster presentation)', Journal of the Society for Gynecologic Investigation (Vol. 13, no. 2: 667) Scientific Program and Abstracts 53rd Annual Meeting, Toronto, Ontario (2006) [E3]

Co-authors: Vicki Clifton

2006Stark MJ, Clifton VL, Wright IM, 'Neonates born to mothers with pre-eclampsia (PE) exhibit altered microvascular function', European Journal of Pediatrics, Barcelona (2006) [E3]

Co-authors: Vicki Clifton

2006Wright IMR, Clifton VL, Stark MJ, 'Characterisation of microvascular function in very preterm infants in the first week of life', JOURNAL OF VASCULAR RESEARCH, Amsterdam, NETHERLANDS (2006)
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Grants and Funding

Summary

Number of grants21
Total funding$1,033,768

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2014 (1 grants)

Vascular adaptation of the newborn: Hydrogen sulphide as a fundamental signalling molecule and novel target for therapy$10,000
Funding Body: University of Newcastle

Project Team
Conjoint Professor Ian Wright, Doctor Phil Jobling, Professor Dirk Van Helden
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020142014
GNo:G1301409

2013 (2 grants)

High-flow nasal cannulae versus ambient oxygen to treat early neonatal respiratory distress in non-tertiary special care nurseries – A multicentre, randomised controlled trial$20,000
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Associate Professor Adam Buckmaster, Conjoint Professor Ian Wright
SchemeRole
Near MissInvestigator
Total AmountFunding StartFunding Finish
$20,00020132013
GNo:G1300699

High-flow nasal cannulae versus ambient oxygen to treat early neonatal respiratory distress in non-tertiary special care nurseries – A multicentre, randomised controlled trial$20,000
Funding Body: University of Newcastle

Project Team
Conjoint Associate Professor Adam Buckmaster, Conjoint Professor Ian Wright
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020132013
GNo:G1300479

2012 (3 grants)

An integrated approach to inotropic support in preterm neonates$75,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Dr Barbara Lingwood, Conjoint Professor Ian Wright, Professor Eugenie Lumbers, Professor Paul Colditz
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$75,00020122014
GNo:G1101107

High-flow nasal cannulae versus ambient oxygen for the treatment of newborn infants with early respiratory distress in non-tertiary special care nurseries - A multicentre, randomised controlled trial$20,000
Funding Body: University of Newcastle

Project Team
Conjoint Associate Professor Adam Buckmaster, Conjoint Professor Ian Wright
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020122012
GNo:G1200676

Precellys Tissue Homogeniser$10,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Roger Smith, Professor Eugenie Lumbers, Conjoint Professor Tam Zakar, Associate Professor Jon Hirst, Conjoint Professor Ian Wright, Doctor Gemma Madsen, Doctor Kaushik Maiti
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020122012
GNo:G1100979

2011 (2 grants)

Research microscope, confocal ready nikon eclipse 90i microscope$69,157
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Roger Smith, Conjoint Professor Tam Zakar, Associate Professor Jon Hirst, Doctor Kaushik Maiti, Doctor Gemma Madsen, Professor Rodney Scott, Conjoint Professor Peter Wark, Professor Paul Foster, Professor Phil Hansbro, Conjoint Professor Ian Wright
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$69,15720112011
GNo:G1100024

A randomised double-blind placebo-controlled trial of the efficacy of Remifentanil for procedural pain in neonates$41,540
Funding Body: Australian and New Zealand College of Anaesthetists

Project Team
Doctor Susan Lord, Conjoint Professor Ian Wright
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$41,54020112011
GNo:G1001089

2010 (1 grants)

Investigating the control of microvascular flow in preterm neonates during the initial extrauterine period$23,025
Funding Body: John Hunter Hospital Charitable Trust Fund

Project Team
Conjoint Professor Ian Wright, Miss Rebecca Dyson
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$23,02520102010
GNo:G1000659

2009 (4 grants)

Characterization of sex-specific differences in cardiovascular adaptation in the first three years of life$543,300
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Ian Wright
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$543,30020092013
GNo:G0188875

Preterm infant carbon monoxide (PICOS)$25,000
Funding Body: Hunter Children`s Research Foundation

Project Team
Conjoint Professor Ian Wright
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$25,00020092009
GNo:G0189805

Validation of energy intake and expenditure in young children using Food Frequency Questionnaires, doubly-labelled water and accelerometers.$24,940
Funding Body: Hunter Medical Research Institute

Project Team
Professor Clare Collins, Conjoint Professor Ian Wright, Professor Robin Callister, Professor Philip Morgan, Doctor Alexis Hure
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$24,94020092009
GNo:G0190405

i-STAT 1 Blood Gas Analyser and Softron BP-98E$13,470
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Ian Wright, Associate Professor Jon Hirst, Professor Eugenie Lumbers, Conjoint Professor Tam Zakar, Doctor Hannah Palliser
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$13,47020092009
GNo:G0189843

2008 (1 grants)

Characterisation of Cardiovascular Adaptation in Newborn Infants$38,336
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Ian Wright, Conjoint Associate Professor Vicki Clifton
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$38,33620082008
GNo:G0189360

2006 (2 grants)

Characterisation of sex-specific differences in pre-term neonatal cardiovascular adaption$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Ian Wright
SchemeRole
John Hunter Childrens Hospital Research FoundationChief Investigator
Total AmountFunding StartFunding Finish
$25,00020062006
GNo:G0186084

Characterisation of sex-specific differences in pre-term neonatal cardiovascular adaption$6,500
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Ian Wright
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$6,50020062006
GNo:G0186083

2002 (1 grants)

Prediction of Birth by Prostaglandin Metabolite Levels in Urine.$24,000
Funding Body: John Hunter Children`s Hospital Research Foundation

Project Team
Conjoint Professor Tam Zakar, Conjoint Professor Ian Wright
SchemeRole
Research Grant (Defunct)Investigator
Total AmountFunding StartFunding Finish
$24,00020022002
GNo:G0182330

2001 (2 grants)

Peripheral vascular tone in the neonatal period - the influence of pre-eclampsia.$24,000
Funding Body: John Hunter Children`s Hospital Research Foundation

Project Team
Conjoint Professor Ian Wright, Conjoint Professor Warwick Giles
SchemeRole
Research Grant (Defunct)Chief Investigator
Total AmountFunding StartFunding Finish
$24,00020012001
GNo:G0181221

Respiratory outcomes in the first three years after neonatal respiratory support: comparison of conventional management.$3,500
Funding Body: John Hunter Children`s Hospital Research Foundation

Project Team
Doctor Chris Wake, Conjoint Professor Ian Wright
SchemeRole
Research Grant (Defunct)Investigator
Total AmountFunding StartFunding Finish
$3,50020012001
GNo:G0181223

2000 (1 grants)

Peripheral vascular tone in the neonatal period - the influence of pre-eclampsia$10,000
Funding Body: University of Newcastle

Project Team
Conjoint Professor Ian Wright, Conjoint Professor Warwick Giles
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020002000
GNo:G0178789

1999 (1 grants)

Evaluation of Columbia Respiratory Care Method in a peripheral tertiary neonatal unit$7,000
Funding Body: University of Newcastle

Project Team
Conjoint Professor Ian Wright
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$7,00019991999
GNo:G0178029
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Research Supervision

Number of current supervisions5
Total current UoN Masters EFTSL0.4
Total current UoN PhD EFTSL0.95

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20142016M Philosophy (Physiotherapy)Co-SupervisorHead Moulding in Preterm Infants: Incidence, Severity and Risk Factor
20122018PhD (Paediatrics)Principal SupervisorEffect of Inotropes and Volume on the Peripheral Microvascular Flow in the Preterm
20112019PhD (Paediatrics)Co-SupervisorDevelopmental and Environmental Determinants on Neonatal Pharmacology
20102014PhD (Paediatrics)Principal SupervisorUnderstanding Microvascular Function in Preterm Neonates
20042008PHD Medical Science
University of Newcastle
Co-SupervisorMicrovascualar blood flow and glucocorticoid metabolism in the preterm infant

Past Supervision

YearProgramSupervisor TypeResearch Title
2013PhD (Reproductive Medicine)Co-SupervisorRelationship Between Renal Volume, Prematurity, Birth Weight and Retinal Microvasculature
2008PhD (Medicine)Consultant SupervisorThe Influence of Sex-Specific Differences in Feto-Placental Glucocorticoid Metabolism on the Preterm Microvasculature and Transitional Circulation
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Conjoint Professor Ian Wright

Work Phone(02) 4921 4362
Fax(02) 4921 4408
Email
PositionConjoint Professor
School of Medicine and Public Health
Faculty of Health and Medicine
The University of Newcastle, Australia
Focus AreaPaediatrics and Child Health
Office
JHH 3641,
John Hunter Hospital,
New Lambton Hts 2305
URL:www.newcastle.edu.au/profile/ian-wright