Profile Image

Staff Profile

Edit

Career Summary

Biography

RHD has developed extensive expertise in cell and molecular profiling technologies based on metabolomics for the measurement of metabolites in cell systems including bacteria, fungi, molluscs and mammalian tissues and fluids.

The analytical approaches have been developed over the last 20 years and have involved using techniques such as gas chromatography - mass spectrometry (GC-MS) and HPLC and have extended towards complex organic analyses of environmental samples to assess pollution profiles and their impacts on metabolism and health.

Over the last 20 years a cell and molecular profiling laboratory has been established for The Pathogenic and Environmental Microbiology Group, which is specifically configured for biological research and contains two GC-MS units, two gas chromatographs (FID and ECD) and HPLC equipment with associated reference databases for peak identification. This represents a unique facility for studying the impact of toxins/pollutants on organisms in the environment and investigating disease mechanisms of pathogenic bacteria. The facilities have also been used via collaborative research programs to investigate anomalies in metabolic homeostasis in patients with chronic illness.

Metabolomics involves profiling metabolites from cell extracts &/or body fluids to identify anomalies in metabolic homeostasis which might be related to specific disease states. Analytical procedures have been developed to assess changes in urine excretion profiles and blood plasma composition in patients and control subjects to determine differences in homeostasis between clinical groups.

A similar approach has been developed for investigating the responses of bacterial pathogens to environmental stresses such as nutrient deprivation, pH and osmotic potential in regard to switching on/off virulence factors. The responses to these stressors appears to modulate the bacterial phenotypes to the extent where highly resistant forms can be generated under certain conditions which could provide a basis to understanding multi-drug resistance in chronic infections.

The models of research have also provided some insight as to how pathogens can exist long term within the host via intracellular invasion mechanisms or the formation of biofilms on prosthetic implants.

The laboratory comprises a highly efficient facility for the PCR-based identification of organisms in water and pathology samples, which has led, for example, to the first description of Anaplasma (Erlichia) platys in dogs from northern Australia.

The research capacity of this specialised unit has led to numerous multidisciplinary research collaborations with medical specialists and environmental scientists which have all led to associated peer review publications. This work could not be carried out by either partner on their own, but together the associations represented truly functional multidisciplinary investigations.

The specialised laboratory has made an excellent learning environment for RHD students to learn state-of-the art techniques in metabolomics and develop professional skills in experimental design, quality control and data processing skills. A major outcome has been the development of skills in multivariate analyses required for metabolomics and similar approaches to measuring complex cellular responses.

The concept of cell and molecular profiling has also been extended to investigating miro-ecology of water supplies to determine possible sources of pathogenic organisms in stored water supplies. The basic principles of multivariate analyses have been applied to differentiate biochemical and bacterial profiles of storage systems to understand potential health risks. This research program also provides a model for investigating biofilms and their capacity to survive under adverse conditions and sequester nutrients and chemical pollutants.

Qualifications

  • Doctor of Philosophy, University of Oxford - UK
  • Bachelor of Science (Agriculture), University of Adelaide

Research

Research keywords

  • Bacterial metabolism
  • Bioaccumulation of pollutants
  • Chronic fatigue illness
  • Pathogenic Bacteria
  • Water contamination
  • Water microbiology

Research expertise

Research History: RHD has developed extensive expertise in the measurement of metabolites in cell systems including bacteria, fungi, molluscs and mammalian tissues and fluids. The analytical approaches have been developed over the last 25 years and have involved using techniques such as gas chromatography - mass spectrometry (GC-MS) and HPLC. RHD brought expertise in GC-MS and HPLC from Oxford to Biological Sciences at The University of Newcastle on his appointment in 1990. Since this appointment, he has developed a specialised cell and molecular profiling laboratory that contains GC, GC-MS, HPLC, HR ICP-MS equipment specifically configured for biological research, making it a unique facility for studying diseases and biological impacts of pollutants. The laboratory also encompasses a microbiology facility for the PCR-based identification of organisms in water and pathology samples.

Research Focus: The primary research focus for RHD has been to use organic and elemental analyses to investigate changes in biochemical homeostasis. The technology platform has facilitated several successful multidisciplinary collaborations which have resulted in publications spanning the fields of ecotoxicology, biotechnology, metabolism and disease research. The research activities fall under 3 types:

(1) Basic research: method development has been a critical component and has included studies on PCR identification of bacteria, the investigation of the effects of factors regulating bacterial production of toxins, the release of low molecular weight metabolites from bacteria, and more recently, the formation of small colony variants following stress.

(2) Applied environmental research: this area has focussed on 2 major fields of activity:

a. Ecotoxicology: the investigation of bioaccumulation of heavy metals and organic contaminants and the subsequent effects on growth and metabolism in oysters.

b. Water research: the investigation of tracking sources of potential pathogens in water catchments, and the passage of microbes into water storage tanks and the associated risks of subsequent water usage. Biofilms play important roles in nutrient and toxic chemical acquisition, and these are currently under investigation.

(3) Clinical research: collaborations have been made with clinicians to investigate potential anomalies in biochemical homeostasis associated with persistent fatigue. These studies include an investigation of fatigue in cancer patients and the changes in blood and urine biochemistry. A second major study has involved the detection of intracellular bacterial pathogens in specific remote communities using dogs as a model for investigating multiple and simultaneous infections.

These 3 areas of research activities have considerable overlap and have facilitated new approaches to metabolic research by developing a capacity for multivariate analyses of complex biochemical and microbial datasets.

Fields of Research

CodeDescriptionPercentage
050299Environmental Science And Management Not Elsewhere Classified50
090799Environmental Engineering Not Elsewhere Classified30
060501Bacteriology20

Collaboration

The development of cell and molecular profiling (CMP) techniques for studying responses of organisms to toxicogenic and pathogenic stress. The research requires multidisciplinary collaboration with colleagues in the Discipline of Biological Sciences as well as in other national and international institutions. The primary foci of research interests includes:

  • The investigation of metabolic responses by staphylococci to environmental stresses
  • The detection of metabolic anomalies in chronic fatigue and chronic pain related disorders.

The primary collaboration occurs between colleagues in the University of Gothenburg.

Administrative

Administrative expertise

RHD has held several administration roles over the period of employment at the University of Newcastle, including membership of the Biohazards Technical Sub-Committee (1994-2001). In more recent years, the administrative involvement has focussed more on roles relating to University Governence.

  • Head of School, School of Environmental and Life Sciences, 2007 - present
  • Deputy Head of School, School of Environmental and Life Sciences, 2004 - 7
  • Assistant Dean for Community Relations (2003-2004)
  • Head of School of Environmental and Life Sciences (2007- present)

The School of Environmental and Life Sciences is a very large school encompassing the disciplines of Biology, Chemistry, Geography, Earth Sciences, Environmental Science and management, and Applied Sciences across both of the university's campuses at Callaghan and Ourimbah. The diverse teaching areas, philosophies and areas of expertise lead to complex budget and management arrangements. The diverse nature of the school generates significant challenges for effectively managing budgets and developing fruitful strategic policies. As HOS, I sit on the Faculty Executive Committee, the Faculty Board, the Faculty strategic planning committee and I chair the school executive committee. Essentially I am responsible for managing over 60 academic staff and delivering a wide range of undergraduate degree programs including 5 majors within the BSc, B Biotechnology and the B Environmental Science and Management. The management responsibilities include:

  • Management of Budgets
  • Part time teaching allocations
  • Chemicals consumables budget for teaching
  • Establishing spreadsheets for modelling, predicting and monitoring expenditure
  • Managing RHD student completions
  • Approval and processing of RHD scholarship applications
  • Course rationalisation, program review and resource management
  • Review discipline course structure with a view to decrease face-to-face hours for academics
  • Manage staff workload
  • Develop good practice for OH&S in the teaching and research environment.

Teaching

Teaching keywords

  • Biochemistry
  • Biology
  • Microbiology

Teaching expertise

Undergraduate Teaching

RHD teaches first year Biology and third year Microbiology. The topic areas for biology include the basic biological chemistry concepts as well as covering a range of topics including DNA, proteins, carbohydrates and lipids. The coursework for Microbiology includes an overview of the diversity of bacteria and archaea, as well as exploring interactions for various symbioses, and an overview of aquatic and terrestrial microbes. In addition, RHD contributes to the newly devised professional lab skills courses in biology which aim to deliver high quality laboratory based training with enhanced resource support at both the 2nd year and 3rd year levels. The second year course aims to provide a range of basic analytical skills for microbiology, biochemistry and molecular biology, as well as for the animal, plant and ecology systems. The third year level courses represent an exciting new concept in undergraduate teaching, where the timetables have been arranged to accommodate 3 day sessions where the students complete an extensive and challenging project. These sessions are designed to reinforce the use of the basic techniques provided in the second year course and teach them concepts in experimental design and data interpretation

Course Development

As Head of School of Environmental and Life Sciences, I have been responsible for a program of course rationalisation within the Biology Discipline and across a range of degree programs. The focus was to devise a delivery platform that provided a diverse range of Biology topics and provided specialised laboratory training for those choosing to major in Biology. This has been achieved by instigating a number of innovations where only those who have need for laboratory training sit the new series of Professional Skills courses offered in first year, second and third years. Other students whom we service for psychology, engineering or environmental studies who do not require such training receive high levels of education in their chosen biological subjects via lectures, tutorials and web-based learning systems. This has enabled a far more effective use of funds with higher than average staff to student ratios.

Postgraduate Training

RHD has been involved in the training of Honours research students in the laboratory as well as PhD students. This level of training relates to instruction in scientific philosophy, experimental design, data processing, statistics, data interpretation and scientific writing. These students learn how to review the literature on a constructive basis and become competent at various biochemical, analytical and microbial techniques. Issues of quality assurance and performance accuracy are developed as major aspects of the research projects.

Edit

Publications

No publications.

Edit

Grants and Funding

Summary

Number of grants74
Total funding$5,660,128

For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (1 grants)

Nutritional supplementation using amino acids in prostate cancer radiotherapy patients experiencing significant fatigue: A model for CFS.$80,060
Funding Body: The Mason Foundation

Project Team
Professor Hugh Dunstan, Doctor Chris Wratten, Doctor Tim Roberts
SchemeRole
Medical and Scientific Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$80,06020132014
GNo:G1200771

2012 (2 grants)

Chronic Fatigue Research: investigating metabolic adaptations of chronic infectious bacteria that could contribute to sustained fatigue$51,127
Funding Body: The Mason Foundation

Project Team
Professor Hugh Dunstan
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$51,12720122014
GNo:G1200885

Teaching Relief - Frisia$14,902
Funding Body: University of Newcastle

Project Team
Professor Hugh Dunstan
SchemeRole
Career Enhancement Fellowship for Academic WomenChief Investigator
Total AmountFunding StartFunding Finish
$14,90220122012
GNo:G1101204

2011 (2 grants)

The evaluation of altered metabolism associated with the development of significant fatigue in prostate cancer patients receiving radiotherapy: Stage two$99,359
Funding Body: The Mason Foundation

Project Team
Professor Hugh Dunstan, Doctor Tim Roberts
SchemeRole
Medical and Scientific Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$99,35920112012
GNo:G1100819

The use of Fluorescent Whitening Compounds as Indicators of Human Faecal Contamination in Environmental Waters$9,968
Funding Body: University of Newcastle

Project Team
Associate Professor Phillip Geary, Professor Hugh Dunstan, Doctor Craig Evans
SchemeRole
Linkage Pilot Research GrantInvestigator
Total AmountFunding StartFunding Finish
$9,96820112011
GNo:G1100039

2010 (6 grants)

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$500,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Adam McCluskey, Laureate Professor John Aitken, Professor Paul Dastoor, Professor Phillip Robinson, Professor Eileen McLaughlin, Emeritus Professor Geoffrey Lawrance, Professor Marcel Maeder, Professor Hugh Dunstan, Doctor Shaun Roman, Associate Professor Rob Atkin, Doctor Clovia Holdsworth, Doctor Mark Baker, Doctor Nikki Verrills, Professor Gottfried Otting, Associate Professor Brett Nixon, Doctor Xiaojing Zhou, Ms Megan Chircop, Doctor Warwick Belcher
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF)Investigator
Total AmountFunding StartFunding Finish
$500,00020102010
GNo:G0190402

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$280,000
Funding Body: University of Newcastle

The Role of Lewis Phenotype and ABH Secretor Status in Relation to Nasal Carriage of Staphylococcal Species in Patients with Chronic Fatigue Syndrome:A Pilot Study$99,910
Funding Body: The Mason Foundation

Project Team
Professor Hugh Dunstan, Doctor Diane Sparkes, Doctor Margaret MacDonald, Doctor Tim Roberts
SchemeRole
Medical and Scientific Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$99,91020102011
GNo:G0190483

The evaluation of altered metabolism associated with the development of significant fatigue in prostate cancer patients receiving radiotherapy$99,359
Funding Body: The Mason Foundation

Project Team
Professor Hugh Dunstan, Conjoint Professor Jim Denham, Doctor Chris Wratten, Doctor Colin Tang, Doctor Anne Capp, Doctor Tim Roberts, Doctor Diane Sparkes, Doctor Margaret MacDonald
SchemeRole
Medical and Scientific Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$99,35920102011
GNo:G1000674

The metabolic response of Staphylococci to environmental stressors$39,600
Funding Body: Gideon Lang Research Foundation

Project Team
Professor Hugh Dunstan, Doctor Tim Roberts
SchemeRole
Scholarship GrantChief Investigator
Total AmountFunding StartFunding Finish
$39,60020102012
GNo:G1000756

Source tracking using alternative faecal indicators in water$10,000
Funding Body: Hunter Water Corporation

Project Team
Associate Professor Phillip Geary, Professor Hugh Dunstan
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020102011
GNo:G1000519

2009 (7 grants)

Electron Microscopes for Nanometer-scale Imaging/Microanalysis in the Materials, Biological, Physical, Engineering and Chemical Sciences$650,000
Funding Body: ARC (Australian Research Council)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)

Technical laboratory support for existing CFS research programs$82,000
Funding Body: The Mason Foundation

Project Team
Professor Hugh Dunstan, Doctor Tim Roberts, Doctor Margaret MacDonald, Doctor Diane Sparkes
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$82,00020092010
GNo:G0189306

Electron Microscopes for Nanometer-scale Imaging/Microanalysis in the Materials, Biological, Physical, Engineering and Chemical Sciences$70,000
Funding Body: ARC (Australian Research Council)

Development of a new clinical diagnostic/bioassay for chronic fatigue syndrome$60,000
Funding Body: Queensland Department of Tourism, Regional Development and Industry

Project Team
Doctor Tim Roberts, Professor Hugh Dunstan
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$60,00020092012
GNo:G0189934

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)

ERF Teaching Relief - Bailey, J$16,820
Funding Body: University of Newcastle

Project Team
Professor Hugh Dunstan, Doctor Judy Bailey
SchemeRole
Equity Research FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$16,82020092009
GNo:G0189833

2008 (5 grants)

Molluscan biomonitor for quantification and impact assessment of endocrine disrupting chemicals in marine ecosystems$135,000
Funding Body: ARC (Australian Research Council)

Project Team
Doctor Geoffrey MacFarlane, Professor Hugh Dunstan, Dr Wayne O'Connor, Dr Lukas Van Zwieten
SchemeRole
Linkage ProjectsInvestigator
Total AmountFunding StartFunding Finish
$135,00020082011
GNo:G0188418

CEF Admin Relief McLaughlin$50,000
Funding Body: University of Newcastle

Project Team
Professor Hugh Dunstan, Professor Eileen McLaughlin
SchemeRole
Career Enhancement Fellowship for Academic WomenChief Investigator
Total AmountFunding StartFunding Finish
$50,00020082008
GNo:G0189257

Molluscan biomonitor for quantification and impact assessment of endocrine disrupting chemicals in marine ecosystems$30,000
Funding Body: Hunter Water Corporation

Project Team
Doctor Geoffrey MacFarlane, Professor Hugh Dunstan, Dr Wayne O'Connor, Dr Lukas Van Zwieten
SchemeRole
Linkage Projects Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$30,00020082010
GNo:G0189236

Small colon variants of Staphylococci and chronic fatigue illness$20,000
Funding Body: Gideon Lang Research Foundation

Project Team
Professor Hugh Dunstan
SchemeRole
Scholarship GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020082008
GNo:G0188674

Molluscan biomonitor for quantification and impact assessment of endocrine disrupting chemicals in marine ecosystems$15,000
Funding Body: Port Stephens Council

Project Team
Doctor Geoffrey MacFarlane, Professor Hugh Dunstan, Dr Wayne O'Connor, Dr Lukas Van Zwieten
SchemeRole
Linkage Projects Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$15,00020082010
GNo:G0189237

2007 (5 grants)

The evaluation of altered metabolism in patients who develop chronic fatigue following cancer radiotherapy (ongoing study)$120,000
Funding Body: The Mason Foundation

Project Team
Doctor Diane Sparkes, Professor Hugh Dunstan, Doctor Tim Roberts, Associate Professor Surinder Baines, Doctor Chris Wratten, Conjoint Professor Jim Denham, Doctor Margaret MacDonald
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$120,00020072008
GNo:G0188042

Predicting channel recovery processes, rates and pathways in the Snowy River$27,380
Funding Body: Southern Rivers Catchment Management Authority

Project Team
Conjoint Professor Wayne Erskine, Professor Hugh Dunstan
SchemeRole
Student Support ProjectInvestigator
Total AmountFunding StartFunding Finish
$27,38020072011
GNo:G0188015

Characterisation of microbial and chemical contaminants, bioreaction and water quantity dynamics in rainwater harvesting systems to optimise design$20,000
Funding Body: University of Newcastle

Project Team
Conjoint Associate Professor Peter Coombes, Professor Hugh Dunstan, Associate Professor Phillip Geary, Doctor Tim Roberts
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020072007
GNo:G0187184

Molluscan biomonitor of estrogenic contaminants$18,000
Funding Body: NSW Department of Primary Industries (Fisheries)

Project Team
Doctor Geoffrey MacFarlane, Professor Hugh Dunstan
SchemeRole
Linkage Projects Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$18,00020072009
GNo:G0188009

Predicting channel recovery processes, rates and pathways in the Snowy River$17,840
Funding Body: NSW Office of Environment and Heritage

Project Team
Conjoint Professor Wayne Erskine, Professor Hugh Dunstan
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$17,84020072012
GNo:G0188050

2006 (4 grants)

The Importance of Small Colony Variants (SCV's) of toxin producing Coagulase-negative Staphylococci in Chronic Fatigue Syndrome$105,000
Funding Body: The Mason Foundation

Project Team
Doctor Tim Roberts, Professor Hugh Dunstan
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$105,00020062009
GNo:G0186782

Impacts of surfaces and storages on the constituents in harvested water$92,000
Funding Body: BlueScope Steel

Project Team
Conjoint Associate Professor Peter Coombes, Professor Hugh Dunstan, Doctor Tim Roberts
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$92,00020062006
GNo:G0186366

The evaulation of altered metabolism in Chronic Fatigue patients following cancer radiotherapy and the efficacy of amino acid supplementation (STAGE TWO)$35,000
Funding Body: The Mason Foundation

Project Team
Professor Hugh Dunstan, Doctor Tim Roberts, Associate Professor Surinder Baines
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$35,00020062006
GNo:G0186783

The Akoya pearl oyster shell as an archival indicator of metal exposure: field-based validation studies$12,696
Funding Body: AINSE (Australian Institute of Nuclear Science & Engineering)

Project Team
Doctor Geoffrey MacFarlane, Professor Hugh Dunstan
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$12,69620062006
GNo:G0185911

2005 (9 grants)

Integrated Water Cycle Management$136,360
Funding Body: BlueScope Steel

Project Team
Conjoint Associate Professor Peter Coombes, Professor Hugh Dunstan
SchemeRole
Research Collaboration AgreementInvestigator
Total AmountFunding StartFunding Finish
$136,36020052009
GNo:G0184442

The evaluation of altered metabolism in chronic fatigue patients following cancer radiotherapy and the efficacy of amino acid supplementation$46,000
Funding Body: TOP Nutrition

Project Team
Professor Hugh Dunstan, Doctor Tim Roberts
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$46,00020052006
GNo:G0185886

The production of bacterial virulence factors and the detection of bacterial pathogens$41,079
Funding Body: The Mason Foundation

Project Team
Professor Hugh Dunstan, Doctor Tim Roberts
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$41,07920052005
GNo:G0185690

The regulation of haemolysin production in coagulase negative staphylococci and the development of modulators of bacterial virulence$40,000
Funding Body: The Mason Foundation

Project Team
Professor Hugh Dunstan, Doctor Tim Roberts
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$40,00020052005
GNo:G0185519

Integrated Water Cycle Management$36,000
Funding Body: BlueScope Water

Project Team
Conjoint Associate Professor Peter Coombes, Professor Hugh Dunstan
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$36,00020052005
GNo:G0185473

Investigation of mosquitos as potential vectors for disease transmission$35,000
Funding Body: The Mason Foundation

Project Team
Professor Hugh Dunstan, Conjoint Associate Professor Peter Coombes
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$35,00020052005
GNo:G0185065

The evaluation of altered metabolism in chronic fatigue patients following cancer radiotherapy and the efficacy of amino acid supplementation$35,000
Funding Body: The Mason Foundation

Project Team
Professor Hugh Dunstan, Doctor Tim Roberts, Conjoint Professor Jim Denham, Doctor Chris Wratten, Associate Professor Surinder Baines
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$35,00020052005
GNo:G0185518

2005 RIBG allocation$19,995
Funding Body: University of Newcastle

Project Team
Professor Hugh Dunstan
SchemeRole
Research Infrastructure Block Grant (RIBG)Chief Investigator
Total AmountFunding StartFunding Finish
$19,99520052005
GNo:G0185834

Bacteriological Investigations into lakeshore water quality adjacent to stormwater quality improvement devices (SQID's)$4,230
Funding Body: Lake Macquarie City Council

Project Team
Associate Professor Phillip Geary, Professor Hugh Dunstan
SchemeRole
Lake Macquarie Environmental Research GrantInvestigator
Total AmountFunding StartFunding Finish
$4,23020052005
GNo:G0185628

2004 (2 grants)

Assessing effects of petroleum oil pollution on estuarine rock platform invertebrate communities$70,668
Funding Body: ARC (Australian Research Council)

Project Team
Doctor Geoffrey MacFarlane, Conjoint Professor Robert Toia, Professor Hugh Dunstan, Miss Michael Cove
SchemeRole
Linkage ProjectsInvestigator
Total AmountFunding StartFunding Finish
$70,66820042006
GNo:G0183625

Assessing effects of petroleum oil pollution on estuarine rock platform invertebrate communities.$17,500
Funding Body: Shell Co Pty Ltd

Project Team
Doctor Geoffrey MacFarlane, Conjoint Professor Robert Toia, Professor Hugh Dunstan
SchemeRole
Linkage Projects Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$17,50020042007
GNo:G0183825

2003 (13 grants)

The characterisation of wastewater distribution patterns for the production of decision support systems for pathogenic risk analysis in water catchments$335,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Hugh Dunstan, Associate Professor Phillip Geary, Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Doctor Tim Roberts, Mrs G Calabria, Mr R Iyadurai, Mr S Wilson, Mr B Brooker, Mr D Pensini, Ms A Kaliska, Mr B Petersen, Mr G Carter, Emeritus Professor Ellak Von Nagy-Felsobuki, Mr P Santoro
SchemeRole
Linkage ProjectsChief Investigator
Total AmountFunding StartFunding Finish
$335,00020032007
GNo:G0182827

Analyses of fatty acids, proteins and carbohydrates in junenile oysters.$45,000
Funding Body: NSW Fisheries

Project Team
Professor Hugh Dunstan
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$45,00020032004
GNo:G0183569

The characterisation of wastewater distribution patterns for the production of decision support systems for pathogenic risk analysis in water catchments$35,000
Funding Body: NSW Department of Commerce

Project Team
Professor Hugh Dunstan, Associate Professor Phillip Geary, Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Doctor Tim Roberts, Mrs G Calabria, Mr R Iyadurai, Mr S Wilson, Mr B Brooker, Mr D Pensini, Ms A Kaliska, Mr B Petersen, Mr G Carter, Emeritus Professor Ellak Von Nagy-Felsobuki, Mr P Santoro
SchemeRole
Linkage Projects Partner fundingChief Investigator
Total AmountFunding StartFunding Finish
$35,00020032006
GNo:G0183256

The characterisation of wastewater distribution patterns for the production of decision support systems for pathogenic risk analysis in water catchments$12,000
Funding Body: Analytical Reference Laboratories Pty Ltd

Project Team
Professor Hugh Dunstan, Associate Professor Phillip Geary, Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Doctor Tim Roberts, Mrs G Calabria, Mr R Iyadurai, Mr S Wilson, Mr B Brooker, Mr D Pensini, Ms A Kaliska, Mr B Petersen, Mr G Carter, Emeritus Professor Ellak Von Nagy-Felsobuki, Mr P Santoro
SchemeRole
Linkage Projects Partner fundingChief Investigator
Total AmountFunding StartFunding Finish
$12,00020032006
GNo:G0183254

The characterisation of wastewater distribution patterns for the production of decision support systems for pathogenic risk analysis in water catchments$12,000
Funding Body: Great Lakes Council

Project Team
Professor Hugh Dunstan, Associate Professor Phillip Geary, Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Doctor Tim Roberts, Mrs G Calabria, Mr R Iyadurai, Mr S Wilson, Mr B Brooker, Mr D Pensini, Ms A Kaliska, Mr B Petersen, Mr G Carter, Emeritus Professor Ellak Von Nagy-Felsobuki, Mr P Santoro
SchemeRole
Linkage Projects Partner fundingChief Investigator
Total AmountFunding StartFunding Finish
$12,00020032006
GNo:G0183257

The characterisation of wastewater distribution patterns for the production of decision support systems for pathogenic risk analysis in water catchments$12,000
Funding Body: Hastings Council

Project Team
Professor Hugh Dunstan, Associate Professor Phillip Geary, Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Doctor Tim Roberts, Mrs G Calabria, Mr R Iyadurai, Mr S Wilson, Mr B Brooker, Mr D Pensini, Ms A Kaliska, Mr B Petersen, Mr G Carter, Emeritus Professor Ellak Von Nagy-Felsobuki, Mr P Santoro
SchemeRole
Linkage Projects Partner fundingChief Investigator
Total AmountFunding StartFunding Finish
$12,00020032006
GNo:G0183259

The characterisation of wastewater distribution patterns for the production of decision support systems for pathogenic risk analysis in water catchments. $12,000
Funding Body: Greater Taree City Council

Project Team
Professor Hugh Dunstan, Associate Professor Phillip Geary, Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Doctor Tim Roberts, Mrs G Calabria, Mr R Iyadurai, Mr S Wilson, Mr B Brooker, Mr D Pensini, Ms A Kaliska, Mr B Petersen, Mr G Carter, Emeritus Professor Ellak Von Nagy-Felsobuki, Mr P Santoro
SchemeRole
Linkage Projects Partner fundingChief Investigator
Total AmountFunding StartFunding Finish
$12,00020032006
GNo:G0184497

The use of pearl-oyster aquaculture for commercially viable bioremedation of contaminated marine environments$10,000
Funding Body: University of Newcastle

Project Team
Professor Hugh Dunstan, Doctor Geoffrey MacFarlane
SchemeRole
Collaborative Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020032003
GNo:G0183148

Determinants of Radiation-induced fatigue in breast cancer patients$9,500
Funding Body: University of Newcastle

Project Team
Conjoint Professor Jim Denham, Doctor Chris Wratten, Professor Hugh Dunstan, Doctor Tim Roberts
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$9,50020032003
GNo:G0182343

The characterisation of wastewater distribution patterns for the production of decision support systems for pathogenic risk analysis in water catchments$9,000
Funding Body: Midcoast County Council

Project Team
Professor Hugh Dunstan, Associate Professor Phillip Geary, Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Doctor Tim Roberts, Mrs G Calabria, Mr R Iyadurai, Mr S Wilson, Mr B Brooker, Mr D Pensini, Ms A Kaliska, Mr B Petersen, Mr G Carter, Emeritus Professor Ellak Von Nagy-Felsobuki, Mr P Santoro
SchemeRole
Linkage Projects Partner fundingChief Investigator
Total AmountFunding StartFunding Finish
$9,00020032005
GNo:G0183258

The use of pearl-oyster aquaculture for commercially viable bioremedation of contaminated marine environments$5,000
Funding Body: Australian Radiata - Pearl Oyster Production Division

Project Team
Professor Hugh Dunstan, Doctor Geoffrey MacFarlane
SchemeRole
University Grant Partner fundingChief Investigator
Total AmountFunding StartFunding Finish
$5,00020032003
GNo:G0183291

The use of pearl-oyster aquaculture for commercially viable bioremedation of contaminated marine environments$5,000
Funding Body: NSW Fisheries

Project Team
Professor Hugh Dunstan, Doctor Geoffrey MacFarlane
SchemeRole
University Grant Partner fundingChief Investigator
Total AmountFunding StartFunding Finish
$5,00020032003
GNo:G0183290

The characterisation of wastewater distribution patterns for the production of decision support systems for pathogenic risk analysis in water catchments$1,500
Funding Body: Hunter Water Corporation

Project Team
Professor Hugh Dunstan, Associate Professor Phillip Geary, Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Doctor Tim Roberts, Mrs G Calabria, Mr R Iyadurai, Mr S Wilson, Mr B Brooker, Mr D Pensini, Ms A Kaliska, Mr B Petersen, Mr G Carter, Emeritus Professor Ellak Von Nagy-Felsobuki, Mr P Santoro
SchemeRole
Linkage Projects Partner fundingChief Investigator
Total AmountFunding StartFunding Finish
$1,50020032003
GNo:G0183251

2002 (8 grants)

Optimal Source Control in Urban Water Cycle Management$299,142
Funding Body: ARC (Australian Research Council)

Project Team
Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Professor Hugh Dunstan, Emeritus Professor Jetse Kalma, Dr Brendan Berghout, Mr I Grimster
SchemeRole
Linkage ProjectsInvestigator
Total AmountFunding StartFunding Finish
$299,14220022004
GNo:G0181151

Optimal Source Control in Urban Water Cycle Management.$100,000
Funding Body: Brisbane City Council

Project Team
Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Professor Hugh Dunstan, Emeritus Professor Jetse Kalma, Dr Brendan Berghout, Mr I Grimster
SchemeRole
Linkage Projects Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$100,00020022005
GNo:G0182251

Optimal Source Control in Urban Water Cycle Management.$94,000
Funding Body: Gosford-Wyong Council`s Water Authority

Project Team
Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Professor Hugh Dunstan, Emeritus Professor Jetse Kalma, Dr Brendan Berghout, Mr I Grimster
SchemeRole
Linkage Projects Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$94,00020022005
GNo:G0182250

Optimal Source Control in Urban Water Cycle Management.$94,000
Funding Body: Hunter Water Corporation

Project Team
Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Professor Hugh Dunstan, Emeritus Professor Jetse Kalma, Dr Brendan Berghout, Mr I Grimster
SchemeRole
Linkage Projects Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$94,00020022005
GNo:G0182249

Optimal Source Control in Urban Water Cycle Management.$60,000
Funding Body: Hunter Region Organisation of Councils

Project Team
Professor George Kuczera, Conjoint Associate Professor Peter Coombes, Professor Hugh Dunstan, Emeritus Professor Jetse Kalma, Dr Brendan Berghout, Mr I Grimster
SchemeRole
Linkage Projects Partner fundingInvestigator
Total AmountFunding StartFunding Finish
$60,00020022004
GNo:G0182252

Electrophysiological investigations of platelet cells derived from patients with schizophrenia and its associations with membranes composition$10,000
Funding Body: University of Newcastle

Project Team
Professor Hugh Dunstan
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020022002
GNo:G0181333

Elemental flow modelling in biofilms from urban rainwater storage tanks$10,000
Funding Body: University of Newcastle

Project Team
Professor Hugh Dunstan, Professor George Kuczera
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020022002
GNo:G0181365

The impact of pearl farming on nutrient and heavy metal cycling in sediments at selected sites in Port Stephens.$5,000
Funding Body: NSW Fisheries

Project Team
Professor Hugh Dunstan, Conjoint Professor Robert Toia
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$5,00020022002
GNo:G0182219

2001 (2 grants)

High-Resolution High-Performance LAS/ICP-MS for Elemental Analysis.$430,000
Funding Body: ARC (Australian Research Council)

Project Team
Emeritus Professor Ellak Von Nagy-Felsobuki, Emeritus Professor Geoffrey Lawrance, Professor Hugh Dunstan, Dr Paul Dubowy, Conjoint Professor Ray Rose, Conjoint Associate Professor Howard Bridgman, Associate Professor David Smith, Dr Philip Binning
SchemeRole
Research Infrastructure Equipment & Facilities (RIEF)Investigator
Total AmountFunding StartFunding Finish
$430,00020012001
GNo:G0179623

Bacteriological Investigations Associated with Stormwater Quality Improvement Devices.$5,232
Funding Body: Lake Macquarie City Council

Project Team
Associate Professor Phillip Geary, Professor Hugh Dunstan
SchemeRole
Lake Macquarie Environmental Research GrantInvestigator
Total AmountFunding StartFunding Finish
$5,23220012001
GNo:G0181487

1999 (1 grants)

2nd World Congress on Chronic Fatigue Symdrome and Related Disorders Brussels, Belgium.$2,400
Funding Body: University of Newcastle

Project Team
Professor Hugh Dunstan
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,40019991999
GNo:G0179079

1997 (1 grants)

Secretion of virulence factors by coagulase negative staphylococcus$5,000
Funding Body: University of Newcastle

Project Team
Professor Hugh Dunstan
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$5,00019971997
GNo:G0176747

1996 (1 grants)

Research into chronic fatigue syndrome.$1
Funding Body: Alison Hunter Memorial Fund

Project Team
Doctor Tim Roberts, Professor Hugh Dunstan
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$119961996
GNo:G0176439

1994 (2 grants)

94 GRANT. Relationship between HLA and immunity to viruses in Australian aborigines.$10,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Barry Boettcher, Professor Hugh Dunstan
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00019941994
GNo:G0173018

The isolation and detection of oxidised DNA base products as markers of oxidative stress.$8,000
Funding Body: University of Newcastle

Project Team
Professor Hugh Dunstan
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$8,00019941994
GNo:G0174738

1992 (2 grants)

Investigating Algae Bloom Formations in the Williams River$69,000
Funding Body: Hunter Water Corporation

Project Team
Professor Hugh Dunstan
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$69,00019921994
GNo:G0173434

Bioaccumulation Studies In Newcastle Waters$7,500
Funding Body: Hunter Water Corporation

Project Team
Professor Hugh Dunstan
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$7,50019921992
GNo:G0173718

1991 (1 grants)

The Use of 13 C-labelled Substrates & Gc-ms tTo Investigate the Organ. Interaction$60,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Hugh Dunstan
SchemeRole
Large GrantChief Investigator
Total AmountFunding StartFunding Finish
$60,00019911991
GNo:G0173826
Edit

Research Supervision

Number of current supervisions4
Total current UoN PhD EFTSL1.45

For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20122019PhD (Chemistry)Co-SupervisorThe Development of Microbial Fuel Cells Using High Mineral Ash Biochars
20112015PhD (Environmental Sc)Co-SupervisorThe Role of Actinomycetes in Taste and Odour Events Involving Geosmin and 2-methylisoborneol in Drinking Water Reservoirs
20112015PhD (Biological Sciences)Co-SupervisorThe Effect of Environmental Stressors on Proteomic Homeostasis of Staphylococci Species
20102014PhD (Biological Sciences)Principal SupervisorAlterations of Metabolic Homeostasis in Staphylococcus Spp. in Response to Environmental Challenges

Past Supervision

YearProgramSupervisor TypeResearch Title
2012M Philosophy (EnvironmentalSc)Co-SupervisorShallow Groundwater Quality and Transport of Contaminants from a Domestic Wastewater System
2012PhD (Biological Sciences)Principal SupervisorVariations in Inorganic and Organic Composition of Roof-Harvested Rainwater: Studies at the Regional and Individual Site Level in Eastern and Southern Australia
2012PhD (Chemistry)Co-SupervisorMass Spectrometry Measurement of Metals and Metalloproteins in Brain Tissue
2011PhD (Environmental Sc)Co-SupervisorMolluscan Biomonitor for Quantification and Impact Assessment of Estrogenic and Metallic Contaminants in Australian Marine Ecosystems
2010PhD (Biological Sciences)Principal SupervisorBacterial and Elemental Loading Patterns in Rainwater Harvesting Systems
2010PhD (Biological Sciences)Co-SupervisorPhylogenetic Diversity and Spatial and Temporal Variability in the Bacterial Populations of Domestic Rainwater Harvesting Systems
2010PhD (Biological Sciences)Co-SupervisorMorphological, Ultra-Structural and Metabolomic Changes Associated with Staphylococcal SPP. Exposed to Environmental Stress Conditions
2009M MedSc (Nutrition & Diet) [R]Co-SupervisorThe Role of Cow's Milk Protein in Children with Chronic Functional Constipation
2009PhD (Environmental Sc)Co-SupervisorBacteriological Studies in Stormwater Quality Improvement Devices (SQIDs) at Lake Macquarie, NSW
2008PhD (Biological Sciences)Principal SupervisorWater Quality, Incidental Treatment Train Mechanisms and Health Risks Associated with Urban Rainwater Harvesting Systems in Australia
2008PhD (Biological Sciences)Principal SupervisorUse of Coprostanol and Related Faecal Sterols for Faecal Source Tracking from Diverse Mixed Land Use Catchments
2007PhD (Biological Sciences)Co-SupervisorDogs, Dwellings and Disease: A Study of Free - Roaming Dogs in a Remote Aboriginal Community
2007PhD (Biological Sciences)Co-SupervisorBiochemical, Immunological, Microbiological and Nutritional Aspects of Autism
2007PhD (Psychology - Science)Co-SupervisorEarly Life Determinants of the Effect of the Endogenous Cannabinoid System on Health Outcomes in Adulthood
2007PhD (Biological Sciences)Principal SupervisorMetabolic Homeostasis in a Subtype of Dyslexia
2006PhD (Biological Sciences)Principal SupervisorEnvironmental Considerations Associated with the Development of an Akoya Pearl Aquaculture Industry in NSW, Australia
2005M Sc (Biological Sc) [R]Co-SupervisorDelta Haemolysin Production of Long-term Staphylococcus epidermidis Cultures
2004PHD Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorThermostable haemolysins from coagulase negative staphylococci
2004PhD (Biological Sciences)Principal SupervisorAlterations in Metabolism in Patients with Chronic Fatigue Syndrome
Edit

Professor Richard (Hugh) Dunstan

Work Phone(02) 4921 5086
Fax(02) 4921 5361
Email
PositionHead of School
School of Environmental and Life Sciences
Faculty of Science and Information Technology
The University of Newcastle, Australia
Focus AreaBiological Sciences
Office
SB203,
Sciences Building,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/hugh-dunstan