Staff Profile
Professor Alistair Sim
Conjoint Professor
School of Biomedical Sciences and Pharmacy
EditCareer Summary
Biography
Since my seminal work in characterising the first ever pharmacological inhibitor of protein phosphatases, I have continued to build an international and national reputation for my work that seeks to understand the ways in which these enzymes regulate cellular signalling and disease. I have made key findings in the way in which protein phosphatases respond to physiological and environmental signals and in the role these enzymes play in neurotransmission and in the initiation of asthma. My publications have now received over 2000 citations and I am ranked in the top 15% of my field internationally. In recognition of this standing in my field I have received annual invitations to speak at key symposia at major international and national conferences. I have also established a number of mutually beneficial international collaborations in the USA and UK. I am one of only 4 Australian researchers on the Editorial Board of The Biochemical Journal, Europes leading scientific journal for biochemistry and I sit on the Biochemistry Grant Review Panel for the National Health and Medical Research Council Australias leading medical research funding body. I have attracted funding from the Wellcome Foundation, UK to establish proteomics facilities and I am a project director of the Australian Cooperative Research Centre for Asthma and Airways new diagnostics proteomics discovery program. I hold an international patent for anticancer therapeutics and current asthma diagnostic work is under intellectual property protection procedures.
Qualifications
- PhD, Australian National University
- Bachelor of Science (Honours), Aberdeen University
Research
Research keywords
- asthma
- cancer
- cell biology
- cell signalling
- exocytosis
- protein kinase
- protein phosphatase
- protein phosphorylation
- protein targeting
- proteomics
Research expertise
Since joining the university in 1989, I have provided national focus and international leadership in cellular signalling with a focus on the regulatory enzymes, protein phosphatases. Current focus is investigation of these key cell regulatory enzymes in the etiology and management of national priority diseases such as asthma and cancer, but also maternal health. I employ a broad range of modern molecular and cellular techniques with a major focus on proteomics for identification of molecular markers of disease
Fields of Research
| Code | Description | Percentage |
|---|
| 110199 | Medical Biochemistry And Metabolomics Not Elsewhere Classified | 50 |
| 060199 | Biochemistry And Cell Biology Not Elsewhere Classified | 35 |
| 110900 | Neurosciences | 15 |
Memberships
Editorial Board.
- Member - The Biochemical Journal
NHMRC Committee
- Grant Review Panel Member - NHMRC
Appointments
Assistant Dean Research, Faculty of Health, The University of Newcastle (Australia) | 01/01/2004 - 01/06/2006 |
Awards
Recognition.
| 2007 | Protein Phosphatase Research Portal Ion Channel Media Group (United States) This is an independent international organisation which ranks all investigators in my field (protein phosphatases) according to the number and citations of publications. It contains over 5000 investigators and I am ranked in the top 15%. See http://www.phosphatase.net/showauthor.php?surname=Sim&initials=AT |
|---|
Invitations
), The Australian Physiology and Pharmacology Society Annual Meeting ), The Australian Physiology and Pharmacology Society, Australia (Conference Presentation - non published.)
| 2006 |
Australian Neuroscience Society Meeting Australian Neuroscience Society , Australia (Conference Presentation - non published.)
| 2006 |
Combio Australian Society for Biochemistry and Molecular Biology, Australia (Conference Presentation - non published.)
| 2005 |
FASEB Summery Research Conference on Protein Phosphatases Federation of American Society for Experimental Biology, United States (Conference Presentation - non published.)
| 2002 |
FEBS Europhosphatase Federation of European Biochemical Societies, Spain (Conference Presentation - non published.)
| 2005 |
FEBS Europhosphatase Meeting Federation of European Biochemical Societies, Belgium (Conference Presentation - non published.)
| 2003 |
Administrative
Administrative expertise
I have occupied a broad range of senior administrative positions within my school, faculty and university.
Teaching
Teaching keywords
- Biochemistry
- Cell signalling
- Medical Biochemistry
- metabolism
Teaching expertise
My main teaching focus is into the medical program and the bachelor of biomedical sciences. Key expertise is in the area of cellular signaling and metabolism.
EditPublications
No publications.
EditGrants and Funding
Summary
| Number of grants | 77 |
|---|
| Total funding | $8,217,601 |
|---|
For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.
- Indicates that the researcher may be seeking students for this project.
Click on a grant title below to expand the full details for that specific grant.
2008 (2 grants)
PP2A: a novel target for leukaemia therapy$300,000
Funding Body: Cancer Council NSW
PP2A: A new target for asthma therapy$20,000
Funding Body: University of Newcastle
2007 (6 grants)
Functional Characterisation of a New Regulatory Mechanism for CaMKII at Synapses in Vivo$526,500
Funding Body: NHMRC (National Health & Medical Research Council)
Heat Shock Proteins in Myometrium$437,750
Funding Body: NHMRC (National Health & Medical Research Council)
FACSAria - Fluorescence activated cell sorter$300,000
Funding Body: Cancer Institute NSW
HMRI Contribution toward FACSAria - Fluorescence activated cell sorter$52,000
Funding Body: Hunter Medical Research Institute
Differential regulation of human mast cell degranulation by discrete forms of protein phosphatase 2A$50,000
Funding Body: Asthma Foundation of New South Wales
Polymerase Chain Reaction (PCR) machine and Spectrophotometer$20,000
Funding Body: NHMRC (National Health & Medical Research Council)
2006 (13 grants)
Advanced technology for transcriptomics, genomics and gene mapping$850,000
Funding Body: ARC (Australian Research Council)
| Project Team |
|---|
| Professor Rodney Scott, Professor Ian Dawes, Professor Ronald Trent, Professor Nicholas Hunt, Emeritus Professor Peter Bergquist, Professor Mark Baker, Emeritus Professor Peter Dunkley, Dr Ruby Lin, Conjoint Professor Peter Gibson, Professor Alistair Sim |
| Scheme | Role |
|---|
| Linkage Infrastructure Equipment & Facilities (LIEF) | Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $850,000 | 2006 | 2006 |
| GNo:G0185547 |
PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Pablo Moscato, Professor Rodney Scott, Professor John Rostas, Professor John Forbes, Conjoint Professor Peter Hersey, Conjoint Professor Stephen Ackland, Conjoint Professor Wayne Smith, Emeritus Professor Peter Dunkley, Conjoint Professor Leonie Ashman, Professor John Attia, Associate Professor Phillip Dickson, Associate Professor Liz Milward, Professor Alistair Sim, Associate Professor Paul Tooney, Associate Professor Regina Berretta, Conjoint Professor David Sibbritt, Conjoint Professor Chris Levi, Professor Xu Dong Zhang, Conjoint Associate Professor Patricia Crock, Conjoint Associate Professor Jeannette Lechner-Scott |
| Scheme | Role |
|---|
| Priority Research Centre | Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $621,143 | 2006 | 2013 |
| GNo:G0186919 |
PRC - Priority Research Centre for Brain & Mental Health Research (CBMHR)$524,282
Funding Body: University of Newcastle
| Project Team |
|---|
| Conjoint Professor Chris Levi, Professor Amanda Baker, Professor Mike Calford, Professor Trevor Day, Emeritus Professor Peter Dunkley, Professor Michael Hazelton, Professor Andrew Heathcote, Professor Brian Kelly, Conjoint Professor Vaughan Carr, Emeritus Professor Patricia Michie, Professor David Pow, Professor John Rostas, Professor Ulli Schall, Professor Alistair Sim, Professor Mike Startup |
| Scheme | Role |
|---|
| Priority Research Centre | Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $524,282 | 2006 | 2013 |
| GNo:G0186947 |
PRC Priority Research Centre for Asthma & Respiratory Diseases$524,282
Funding Body: University of Newcastle
Live cell imaging facility$149,100
Funding Body: Cancer Institute NSW
Targeting protein phosphatases to control mast cell activation$50,000
Funding Body: Asthma Foundation of New South Wales
A novel approach to the control of mast cell activation$20,000
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Near Miss Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $20,000 | 2006 | 2006 |
| GNo:G0186063 |
Functional Characterisation of CaMKII Phosphorylate at a New Site in vivo$20,000
Funding Body: University of Newcastle
Identification of early-life signals induced in response to infection that predispose to asthma in later life$20,000
Funding Body: University of Newcastle
Novel protein phosphatase interactions in cancer$10,000
Funding Body: Hunter Medical Research Institute
High speed computer for a live cell imaging system$3,000
Funding Body: Hunter Medical Research Institute
Human Proteome Organisation World Congress, Long Beach California, 28/10/2006 - 1/11/2006$2,400
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $2,400 | 2006 | 2006 |
| GNo:G0187003 |
BioRad Mini-PROTEAN3 Electrophoresis system$995
Funding Body: Hunter Medical Research Institute
2005 (5 grants)
High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation$207,189
Funding Body: ARC (Australian Research Council)
| Project Team |
|---|
| Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Peter Lewis, Conjoint Associate Professor Renate Griffith, Conjoint Professor Ray Rose, Emeritus Professor John Patrick, Associate Professor David McCurdy, Professor Adam McCluskey, Emeritus Professor Ellak Von Nagy-Felsobuki, Emeritus Professor Peter Dunkley, Associate Professor Phillip Dickson, Professor John Rostas, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Professor Paul Foster, Conjoint Professor Peter Gibson, Professor Roger Smith, Professor Alistair Sim, Associate Professor Paul Tooney, Dr Fraser Ross |
| Scheme | Role |
|---|
| Linkage Infrastructure Equipment & Facilities (LIEF) | Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $207,189 | 2005 | 2005 |
| GNo:G0184185 |
Novel Substrates for High Sensitivity MALDI$14,696
Funding Body: University of Newcastle
2005 RIBG allocation$14,500
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Research Infrastructure Block Grant (RIBG) | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $14,500 | 2005 | 2005 |
| GNo:G0185804 |
Regulation of Insulin Secretion by Protein Phosphatases$10,000
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Project Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $10,000 | 2005 | 2005 |
| GNo:G0184726 |
12th International Conference on Second Messengers and Phosphoproteins, 10-14 July 2005$2,500
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $2,500 | 2005 | 2005 |
| GNo:G0185611 |
2004 (6 grants)
Differential regulation of two modes of exocytosis by protein phosphatases$393,750
Funding Body: NHMRC (National Health & Medical Research Council)
Biacore3000-Expansion of Proteomics Facility$187,341
Funding Body: ARC (Australian Research Council)
| Project Team |
|---|
| Professor Alistair Sim, Laureate Professor John Aitken, Emeritus Professor Peter Dunkley, Professor John Rostas, Associate Professor Phillip Dickson, Conjoint Professor Leonie Ashman, Professor Roger Smith, Professor Gordon Burns, Professor Adam McCluskey, Associate Professor Paul Tooney, Dr Fraser Ross, Conjoint Professor Ray Rose |
| Scheme | Role |
|---|
| Linkage Infrastructure Equipment & Facilities (LIEF) | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $187,341 | 2004 | 2004 |
| GNo:G0183030 |
Biacore3000-Expansion of Proteomics Facility$70,660
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Equipment Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $70,660 | 2004 | 2004 |
| GNo:G0184281 |
Investigation of a novel molecular target for a new anti-ashtma therapy$16,000
Funding Body: Hunter Medical Research Institute
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Research Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $16,000 | 2004 | 2004 |
| GNo:G0183752 |
Regulation of the neuronal RNA binding protein, pipping by protein phosphorylation$14,500
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Project Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $14,500 | 2004 | 2004 |
| GNo:G0183426 |
12th International Conference on Second Messengers and Phosphoproteins, 3-7 August 2004$2,400
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $2,400 | 2004 | 2004 |
| GNo:G0184493 |
2003 (3 grants)
High Throughput 2-dimensional electrophoresis$36,443
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Equipment Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $36,443 | 2003 | 2003 |
| GNo:G0183062 |
Regulation of neuronal exocytosis by protein phosphatase 2A$15,000
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Project Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $15,000 | 2003 | 2003 |
| GNo:G0182371 |
EMBO Europhosphatases 2003 Barceloa, Spain 28 June - 3 July 2003$2,400
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $2,400 | 2003 | 2003 |
| GNo:G0183232 |
2002 (6 grants)
Proteomic and Genomic Analysis Facility.$473,332
Funding Body: Wellcome Trust
Mechanisms of Glutamate Receptor Maturation in Chicken Brain$417,000
Funding Body: NHMRC (National Health & Medical Research Council)
Peltier Thermal Cycler and associated equipment essential for establishing cDNA Retroviral Libraries$21,315
Funding Body: NHMRC (National Health & Medical Research Council)
The role of Protein Phosphatase 2A in synaptic vesicle transport$13,000
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Project Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $13,000 | 2002 | 2002 |
| GNo:G0181407 |
Interaction of Protein Phosphatase 2A with the Neuron-specific RNA binding Protein, PIPPin$10,000
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim, Professor Judith Scott |
| Scheme | Role |
|---|
| Project Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $10,000 | 2002 | 2002 |
| GNo:G0181406 |
FASEB Summer Research Conference on Protein Phosphatases, USA 13 - 19 July, 2002$2,400
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $2,400 | 2002 | 2002 |
| GNo:G0182166 |
2001 (5 grants)
Reciprocal Regulation of Kinases and Phosphatases in Long Term Synaptic Plasticity$15,000
Funding Body: University of Newcastle
Control of Catecholamine Synthesis by Tyrosine Hydroxylase.$13,000
Funding Body: University of Newcastle
Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770
Funding Body: NHMRC (National Health & Medical Research Council)
Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770
Funding Body: University of Newcastle
EMBO Conference on Protein Phosphatases and Phosphorylation, Germany 8-12 July 2001$2,400
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $2,400 | 2001 | 2001 |
| GNo:G0181000 |
2000 (3 grants)
Targeting Protein Phosphatase 2A to Regulate DNA Repair.$20,000
Funding Body: Hunter Medical Research Institute
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Research Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $20,000 | 2000 | 2001 |
| GNo:G0180546 |
Secretatogue-Induced Translocation of Protein Phosphatase 2A in Mast Cells.$14,500
Funding Body: ARC (Australian Research Council)
| Project Team |
|---|
| Professor Alistair Sim, Dr R Ludowyke |
| Scheme | Role |
|---|
| Small Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $14,500 | 2000 | 2000 |
| GNo:G0178966 |
FASEB Summer Research Conference on Protein Phosphatases, USA 23-29 July 2000$2,400
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $2,400 | 2000 | 2000 |
| GNo:G0179852 |
1999 (5 grants)
Targeting of Neuronal Protein Phosphatase 2A$335,505
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Project Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $335,505 | 1999 | 2001 |
| GNo:G0178361 |
Confocal Laser Scanning Microscope Facility.$203,107
Funding Body: ARC (Australian Research Council)
| Project Team |
|---|
| Laureate Professor John Aitken, Emeritus Professor John Patrick, Conjoint Professor Christina Offler, Associate Professor David McCurdy, Conjoint Professor Ray Rose, Doctor Tim Roberts, Conjoint Associate Professor Russell Jones, Doctor John Clulow, Professor John Rostas, Professor Alistair Sim, Professor Gordon Burns, Conjoint Professor Loris Chahl, DR DAVID KAY |
| Scheme | Role |
|---|
| Large Equipment Grant | Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $203,107 | 1999 | 1999 |
| GNo:G0177945 |
FPLC Protein Purification System$16,000
Funding Body: NHMRC (National Health & Medical Research Council)
The Role of A-Kinase Anchoring Proteins in Directing the Specificity of Protein Phosphatase 1 Action in Neurons.$11,500
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Project Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $11,500 | 1999 | 1999 |
| GNo:G0178124 |
EMBO/FEBS Conference on Protein Phosphorylation and Protein De Panne, Belgium.$2,400
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $2,400 | 1999 | 1999 |
| GNo:G0180486 |
1998 (5 grants)
Molecular Dynamics Storm 860 Tri-mode Analysis System$35,000
Funding Body: Ramaciotti Foundations
| Project Team |
|---|
| Professor Alistair Sim, Professor John Rostas, Emeritus Professor Peter Dunkley, Dr Stephen Bunn, Dr Tat Cheah, Conjoint Professor Kenneth Beagley, Conjoint Professor Ray Rose, Professor Judith Scott, Doctor Cheng Chan, Professor Roger Smith |
| Scheme | Role |
|---|
| Research Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $35,000 | 1998 | 1998 |
| GNo:G0177453 |
Control of the nervous system by protein phosphatases and anchoring prteins$19,000
Funding Body: Department of Industry, Science & Resources
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Bilateral S&T Program (Defunct) | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $19,000 | 1998 | 1998 |
| GNo:G0177195 |
Identification of protein phosphatases acting on Tyrosine Hydroxylase in bovine adrenal chromaffin cells.$19,000
Funding Body: University of Newcastle
The Role of Protein Phosphatases in Allergic Response Mast Cell Secretion$16,486
Funding Body: Asthma Foundation of New South Wales
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Research Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $16,486 | 1998 | 1999 |
| GNo:G0177600 |
Characterisation of Neuronal Protein Phosphatase 1 Binding Proteins.$11,500
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Project Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $11,500 | 1998 | 1998 |
| GNo:G0177262 |
1997 (5 grants)
Role of Protein Phosphorylation in the Control of Glutamate Release from Nerve Terminals.$178,409
Funding Body: NHMRC (National Health & Medical Research Council)
Characteristation of Novel Molecular Probes for Protein Phosphatases.$160,000
Funding Body: ARC (Australian Research Council)
Modulation of Neurotransmitted Release by Carboxyl-methylation and tyrosine Phosphorylation of Protein Phosphatase type 2A.$18,000
Funding Body: ARC (Australian Research Council)
Molecular Characterisation of Protein Phosphatase 2A.$8,500
Funding Body: Ian Potter Foundation
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Research Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $8,500 | 1997 | 1997 |
| GNo:G0176967 |
Joint Meeting of the International and American Societies for Neurochemistry, Boston, USA, 20-26 July 1997$2,500
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $2,500 | 1997 | 1997 |
| GNo:G0179567 |
1996 (3 grants)
Molecular characterisation of cytoskeletal protein phosphatase 2A$60,662
Funding Body: ARC (Australian Research Council)
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Multi-Year Small Grant Scholarship | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $60,662 | 1996 | 1999 |
| GNo:G0175745 |
Purchase Shaking Incubator and Peltier Thermocycler$10,000
Funding Body: Ian Potter Foundation
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Research Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $10,000 | 1996 | 1996 |
| GNo:G0176056 |
Federation of American Societies for Experimental Biology, Colorado, USA, 21-26 July 1996$2,400
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $2,400 | 1996 | 1996 |
| GNo:G0176477 |
1995 (4 grants)
Regulation of neuronal protein phosphatases types 1 & 2A.$218,471
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Project Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $218,471 | 1995 | 1997 |
| GNo:G0174526 |
95APP. High resolution purification of intra-cellular signalling proteins from brain by FPLC.$20,000
Funding Body: Ramaciotti Foundations
Phosphorylation of glycoprotein GP-180:- Implications for NMDA-type glutamate receptor function$9,000
Funding Body: University of Newcastle
Intern. Society for Neurochemistry, Japan, 2-7 July$2,400
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $2,400 | 1995 | 1995 |
| GNo:G0176855 |
1994 (2 grants)
The control of tyrosine hydroxylase activity by protein phosphorylation.$6,000
Funding Body: University of Newcastle
Do sigma binding site ligands modulate neurotransmission by molecular mechanisms involving protein phosphorylation in neuronal tissue$5,000
Funding Body: University of Newcastle
1993 (2 grants)
Advance Warning Of Cyanobacterial Activity$119,637
Funding Body: Urban Water Research Association
'ISN Bien. Meet',Montpellier-22 - 27 Aug.93,'European Protein Phosphatase Meeting'Bressanone,19-23 Sept 1993,'1st Int. Symp.on Cyanobacteria,Bath,27-29Sept$2,400
Funding Body: University of Newcastle
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Travel Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $2,400 | 1993 | 1993 |
| GNo:G0174350 |
1992 (2 grants)
92,93,94GRANT. The Regulation Of Protein Phosphatases In The Brain$183,006
Funding Body: NHMRC (National Health & Medical Research Council)
Characterisation Of Novel Inhibitions And Activators Of Protein Phosphatases And Protein Kinases Isolated From Australian Marine Invertebrates.$25,000
Funding Body: ARC (Australian Research Council)
| Project Team |
|---|
| Professor Alistair Sim |
| Scheme | Role |
|---|
| Small Grant | Chief Investigator |
| Total Amount | Funding Start | Funding Finish |
|---|
| $25,000 | 1992 | 1992 |
| GNo:G0173619 |
EditResearch Supervision
| Number of current supervisions | 0 |
|---|
For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.
Past Supervision
| Year | Program | Supervisor Type | Research Title |
|---|
| 2012 | PhD (Medical Biochemistry) | Co-Supervisor | The Role of Protein Phosphatase 2A as a Tumour Suppressor in Breast Cancer |
| 2011 | PhD (Medical Biochemistry) | Co-Supervisor | Regulation of Mast Cell Degranulation by Protein Phosphatase 2A |
| 2010 | PhD (Medical Biochemistry) | Co-Supervisor | Regulation of the Tumour Suppressor PP2A by Oncogenic Tyrosine Kinases |
| 2004 | PhD (Medical Biochemistry) | Sole Supervisor | Yeast Two-Hybrid Analysis of Protein Phosphatase 2A Binding Proteins |
| 2004 | PhD (Medical Biochemistry) | Principal Supervisor | Differential Regulation of Two Modes of Synaptic Vesicle Exocytosis by Protein Phosphorylation |