Medical Research Future Fund (MRFF)

The Medical Research Future Fund (MRFF) is a $20 billion long-term investment supporting Australian health and medical research. The MRFF aims to transform health and medical research and innovation to improve lives, build the economy and contribute to health system sustainability.

The MRFF funds research around 4 key themes: patients, researchers, research missions and research translation. The MRFF funding process allocates funding to these themes according to national research priorities.

Further information about the MRFF can be found on the Department of Health MRFF webpage.

Please note: Research Grants communicates information about all MRFF schemes (regardless of who they are administered by) via our internal NHMRC mailing list. It is strongly recommended that all applicants subscribe to the Research Grants NHMRC mailing list for up to date information on these schemes.

Some MRFF opportunities allow for a limited number of applications for the funding round. In this case, an internal EOI process will be required and will be advertised via the Research Grants NHMRC mailing list.

MRFF Links and Resources

Open MRFF Opportunities

Managed bySchemeOpen E&C Check Period Min Data University Deadline for Final ApplicationSubmission
NHMRC 2024 Paediatric Brain Cancer Research Grant Opportunity Mon 5 February 2024 Wed 22 - Tue 28 May 2024 Wed 22 May 2024 9:00am Tue 4 June 2024 Wed 19 June 2024
Dept. Health & Aged Care National Critical Research Infrastructure Initiative – 2023 Innovative Trials Tue 6 February 2024 Thu 13 - Wed 19 June 2024 N/A 9:00am Wed 26 June 2024 Wed 10 July 2024
NHMRC 2024 Indigenous Health Research Grant Opportunity Wed 7 February 2024 Thu 27 June - Wed 3 July 2024 Wed 26 June 2024 9:00am Wed 10 July 2024 Wed 24 July 2024
NHMRC 2024 Early to Mid-Career Researchers Grant Opportunity* Wed 7 February 2024 Thu 27 June - Wed 3 July 2024 Wed 26 June 2024 9:00am Wed 10 July 2024 Wed 24 July 2024
NHMRC Stem Cell Therapies Mission -  2024 Stem Cell Therapies Grant Opportunity Wed 7 February 2024 Thu 27 June - Wed 3 July 2024 Wed 26 June 2024 9:00am Wed 10 July 2024 Wed 24 July 2024
NHMRC 2024 Cardiovascular Health Grant Opportunity Wed 7 February 2024 Thu 4 - Wed 10 July 2024 Wed 3 July 2024 9:00am Wed 17 July 2024 Wed 31 July 2024
NHMRC 2024 Survivorship Care and Collaborative Research Prioritisation Grant Opportunity Wed 7 February 2024 Thu 4 - Wed 10 July 2024 Wed 3 July 2024 9:00am Wed 17 July 2024 Wed 31 July 2024
Dept. Health & Aged Care 2024 BioMedTech IncubatorTue 27 February 2024Thu 4 - Wed 10 July 2024N/A9:00am Wed 17 July 2024Wed 31 July 2024
NHMRC2024 International Clinical Trial Collaborations Grant Opportunity (Round 1)Wed  6 March 2024Thu 4 - Wed 10 July 2024Wed 3 July 20249:00am Wed 17 July 2024Wed 31 July 2024
NHMRC Emerging Priorities and Consumer Driven Research Initiative and Primary Health Care Research Initiative - 2023 Multidisciplinary Models of Primary Care Grant Opportunity - Stream 4 Wed 18 October 2023 Thu 11 - Wed 17 July 2024 Wed 10 July 2024 9:00am Wed 24 July 2024 Wed 7 August 2024
NHMRC Preventive and Public Health Research Initiative -  2024 Maternal Health and Healthy Lifestyles Grant Opportunity Wed 14 February 2024 Thu 11 - Wed 17 July 2024 Wed 10 July 2024 9:00am Wed 24 July 2024 Wed 7 August 2024
NHMRC Dementia, Ageing and Aged Care Mission - 2024 Dementia, Ageing and Aged Care Grant Opportunity Wed 14 February 2024 Thu 11 - Wed 17 July 2024 Wed 10 July 2024 9:00am Wed 24 July 2024 Wed 7 August 2024
NHMRC Million Minds Mental Health Research Mission – 2024 Mental Health Research Grant Opportunity Wed 14 February 2024 Thu 11 - Wed 17 July 2024 Wed 10 July 2024 9:00am Wed 24 July 2024 Wed 7 August 2024
NHMRC Preventive and Public Health Research Initiative - 2024 Enhancing Medical Device Surveillance Through Registries Grant Opportunity Wed 14 February 2024 Thu 18 - Wed 24 July 2024 Wed 17 July 2024 9:00am Wed 31 July 2024 Wed 14 August 2024
NHMRC2024 International Clinical Trial Collaborations Grant Opportunity (Round 2)Wed  6 March 2024Wed 8 - Thu 14 January 2025Wed 4 December 20249:00am 21 January 2025Wed 5 February 2025

*Anyone intending to apply for Stream 3 of this grant opportunity is required to submit an NOI Form (DOC) to Research Grants.

Eligibility and Compliance (E&C) Checks can be booked through the 'MRFF Opportunities' tile on the Online Booking System website. Bookings for a scheme generally open the day after the scheme opens. Given the tight turnaround on some MRFF opportunities, E&C checks may not be available for all schemes.

Please contact the Research Grants Team via email if you intend on applying for an MRFF opportunity.

Past MRFF Opportunities

Managed BySchemeOpenedSubmission
NHMRCEmerging Priorities and Consumer Driven Research Initiative and Primary Health Care Research Initiative - 2023 Multidisciplinary Models of Primary Care Grant Opportunity - Stream 1,2 & 318 October 202310 April 2024
NHMRC2023 Childhood Mental Health Research Grant Opportunity11 October 202327 March 2024
NHMRCIndigenous Health Research Fund – 2023 Indigenous Health Research Grant Opportunity28 June 20236 March 2024
Dept. Health & Aged Care2023 Targeted Translation Research Accelerator - Cardiovascular Disease and Diabetes Mechanisms Grant Opportunity7 November 202321 February 2024
Dept. Health & Aged Care2023 Targeted Translation Research Accelerator – Cardiovascular Disease and Diabetes Drugs and Devices7 November 202321 February 2024
NHMRCPreventive and Public Health Research Initiative -  2023 Optimising Screening, Diagnosis and Management of Obstructive Sleep Apnoea Grant Opportunity6 September 202314 February 2024
NHMRCTraumatic Brain Injury Mission - 2023 Traumatic Brain Injury Grant Opportunity28 June 202329 November 2023
NHMRCMillion Minds Mental Health Research Mission - 2023 Mental Health Research Grant Opportunity5 July 202329 November 2023
NHMRCGenomics Health Futures Mission – 2023 Genomics Health Futures Grant Opportunity5 July 202329 November 2023
NHMRCStem Cell Therapies Mission - 2023 Stem Cell  Therapies Grant Opportunity26 April 202315 November 2023
NHMRCDementia, Ageing and Aged Care Mission - 2023 Dementia, Ageing and Aged Care Grant Opportunity26 April 202315 November 2023
NHMRCCardiovascular Health Mission - 2023 Cardiovascular Health Grant Opportunity26 April 202315 November 2023
NHMRC2023 Post-Acute Sequelae of COVID-19 Grant Opportunity6 September 20231 November 2023
Dept. Health & Aged Care2023 Global Health Grant Opportunity27 March 202320 September 2023
NHMRC2023 Models of Care for Sexuality & Gender Diverse People & People with Innate Variations of Sex Characteristics1 March 202323 August 2023
NHMRCPrimary Health Care Research Initiative: Primary Health Care Research Grant8 February 20232 August 2023
Dept. Health & Aged CareClinician Researchers Initiative: 2023 Clinician Researchers: Applied Research in Health Grant Opportunity15 February 20232 August 2023
DIISMedical Research Commercialisation Initiative:  2023 BioMedTeach Incubator - Dementia and Cognitive Decline Grant Opportunity20 February 202331 July 2023
NHMRCClinical Trials Activity Initiative - 2023 International Clinical Trials Collaborations Grant (Round 1)1 March 202326 July 2023
NHMRC2022 Clinical Trials Activity Grant Opportunity14 December 202228 June 2023
NHMRC2023 Early to Mid-Career Researchers Grant Opportunity15 February 202321 June 2023
NHMRCPreventive and Public Health Research Initiative: 2023 Chronic Respiratory Conditions Grant Opportunity8 February 202314 June 2023
NHMRCPreventive and Public Health Research Initiative: 2023 Maternal Health and Healthy Lifestyles Grant Opportunity8 February 202314 June 2023
NHMRCPreventive and Public Health Research Initiative: 2023 Consumer-Led Research Grant Opportunity8 February 202314 June 2023

Further Information for MRFF's administered by the NHMRC

The NHMRC is required to publish Grant Guidelines and all associated scheme documents on GrantConnect, the Australian Government whole-of-government, web-based, grant information system. You will need to sign in or create a User Registration account in GrantConnect to access all relevant documentation for NHMRC applications.

Once you have signed in to GrantConnect, the essential documents can be found by searching for the relevant scheme under ‘grant opportunities’ (open schemes) or ‘forecast opportunities’ (upcoming schemes). As the NHMRC often updates documents after the scheme opens, it is highly recommended that you sign up for alerts by editing your profile.

If you encounter any problems accessing or downloading these documents please contact research-applications@newcastle.edu.au or 4921 7733.

UON Documents

The Research-NHMRC mailing list is managed by Research Grants and is used to communicate essential information regarding grant opportunities offered by the National Health and Medical Research Council (NHMRC). Information regarding opportunities offered through the Medical Research Future Fund (MRFF), regardless of who administers the grant (i.e NHMRC, Department of Health, Depart of Industry, Science, Energy and Resources), are also communicated via this list.

Internal EOI processes for limited round MRFF opportunities are also be advertised via this list.

Information about applying, minimum data deadlines, eligibility information, changes to guidelines and conditions of award, progress report requirements etc. are communicated via this list.

If you currently hold an NHMRC/MRFF grant or fellowship, or intend on applying for one, Research Grants strongly recommends subscribing to this list.

Subscribe to the Research-NHMRC Mailing list (UON staff and students only)

NHMRC uses Sapphire for all grant rounds.

All researchers listed on an NHMRC grant application (including AIs, partner organisations and international CIs/AIs) must have a Sapphire account. New account requests should be submitted as soon as possible and at least 72 hours prior to application close. Any account activation processes started within 72 hours of the round close cannot be guaranteed to be actioned by NHMRC before the round closes.

Video tutorials are available from the Sapphire Knowledge Base page and NHMRC has a dedicated Sapphire Help Desk:

T: 1800 500 983 (Australia) 
+61 2 6217 9451 (International)

The NHMRC updates the  Sapphire web page with the latest news and other relevant information.

Researchers should confirm all Profile data is complete and up-to-date prior to submitting an application.

A summary of the key changes for Sapphire Profile and NHMRC’s recommendations for checking your profile data is available on the NHMRC Sapphire - Profile Update webpage.

CI Eligibility Limits and Sapphire

Unlike RGMS, Sapphire does not contain the functionality to perform validation checks to identify potential eligibility issues.

Research Grants strongly recommends that CIAs ensure that all CIs carefully check to ensure they meet the eligibility requirement for the specific scheme – noting that for some schemes eligibility is limited to one application as CI.

The NHMRC will rule all applications ineligible in instances where any CI (CIA-CIJ) is in excess of the maximum number of grants they are eligible to apply for or hold.

Please contact Research Grants if you are unsure of your eligibility so we can assist.

Eligibility for schemes is outlined in the scheme specific Guidelines. CIs are advised to carefully review this information to ensure that all members of the research team to be named on an application meet the scheme specific eligibility requirements.

CIs may submit a total of two applications across the Ideas, Investigator and Synergy Grant schemes in any given funding round dependent on the number of grants already held.

It is important to note:

  • The Investigator Grants 2024 (closed 8 November 2023), Synergy Grants 2024 (opened 7 February 2024) and Ideas Grants 2024 (opening 20 March 2024) are considered the same funding round;
  • An Investigator Grant 2024 application will count as one of the maximum two applications across the three schemes;
  • If the Investigator Grant 2024 is successful, any Ideas Grant the Investigator Grant applicant is listed on as a CI, irrespective of whether it is CIA-CIJ, will be removed and excluded from consideration.

If any CI (CIA-CIJ) submits an Ideas, Investigator or Synergy Grant application(s), in the same funding round, in excess of the maximum for which they are eligible to apply or hold, the breaching application(s) (i.e. the last submitted) on which that CI is named may be ineligible and excluded from consideration, irrespective of the scheme to which they have applied, and that CI’s position or role on the application.

Research Grants recommends that applicants carefully review the NHMRC eligibility tool and the specific scheme Guidelines, to determine eligibility prior to commencing an application or agreeing to be a CI on an application.  Please contact Research Grants if you are unsure of your eligibility so we can assist.

Minimum data must be entered in Sapphire by the scheme-specific deadline to allow the NHMRC to find suitable peer reviewers for the application. Applicants must complete the required fields with correct information. Using placeholder text such as “text”, “synopsis” or “xx” etc. is not acceptable as minimum data. Minimum data requirements for each scheme are specified in the scheme Grant Guidelines.

Failure to meet the Minimum Data deadline will result in the application not proceeding.

Research Grants uses an online booking process to manage optional Eligibility and Compliance Checks on applications for NHMRC Schemes. Scientific content is not reviewed.

A booking must be made within the allocated E&C Check period for each scheme. Applicants are strongly encouraged to commence their application in Sapphire ASAP after the scheme opens so they can book their preferred day for an E&C Check. Bookings without a Sapphire application ID will be cancelled.

As per MRFF scheme guidelines, the Chief Investigator A (CIA) must seek written agreement from all CIs for the final MRFF application to be certified in Sapphire for submission, to be named in the application, to participate in the manner described in the application and to the use of their personal information as described in the NHMRC Privacy Policy. The RAO will not be authorised to submit the application to the MRFF until all CIs have completed this step. By certifying the application in Sapphire, the CIA is also agreeing to the conditions set out in the MRFF Certification Form.

Completed MRFF Certification Forms should be returned to Research Grants by 9:00am on the scheme's internal due date.

Download the MRFF Certification Form (DOC)

Please see the NHMRC Submission Procedure on the NHMRC Grants webpage and the Online Booking System User Guide for instructions on how to make a booking for an Eligibility and Compliance Check.

Once complete, the CIA must certify and submit the application in Sapphire via the Certification page. To do this, select the ‘Certification’ page in Sapphire, select ‘Certify and submit to RAO'. This will result in the status changing to 'Submitted to RAO' - which equates to 'Research Administration Office' (NOT the NHMRC).

All schemes except for Partnership Projects

Applications involving Hunter New England Local Health District (HNELHD) patients, sites and/or HNELHD Chief or Associate Investigator(s) require the appropriate HNELHD manager(s) approval be obtained prior to the University of Newcastle internal deadline.

Please contact the HNELHD Research office if you have any questions relating to HNELHD processes or research involving HNELHD patients or sites.

Please note that applicants who are proposing to access HNELHD patients or sites but who do not have a formal affiliation with HNELHD, will need to ensure the application team includes a HNELHD investigator in accordance with HNELHD requirements.

Partnership Projects

As a Partner Organisation letter of support may be required, Partnership Project applications involving Hunter New England Local Health District (HNELHD) patients, sites and/or HNELHD Chief or Associate Investigator(s) require the appropriate HNELHD manager(s) approval be obtained prior to the University of Newcastle internal deadline.

Please contact the HNELHD Research office if you have any questions relating to their processes or research involving HNELHD patients or sites.

Please note that applicants who are proposing to access HNELHD patients or sites but who do not have a formal affiliation with HNELHD, will need to ensure the application team includes a HNELHD investigator in accordance with HNELHD requirements.

The NHMRC has released a Toolkit for Consumer and Community Involvement in Health and Medical Research to ‘provide practical advice on engaging with consumers and the community to undertake high quality and relevant research’.

The Toolkit comprises of five individual resources available for download from the Consumer and community engagement page.

The Toolkit has been designed by the NHMRC and its Community and Consumer Advisory Group to complement the 2016 Statement on Consumer and Community Involvement in Health and Medical Research

Research Liaison Librarians

Research Liaison Librarians offer a number of specialist research services and resources, including advice and support for undertaking literature searches, systematic reviews, referencing, citation analysis, current awareness, promotion of research, and management of research data.

Contact your school’s Research Liaison Librarian to discuss your research needs.

Impact Case Studies

The assessment criteria for some NHMRC schemes now include research impact wherein applicants are required to demonstrate the impact of a project or program of research.

Applicants will be assessed based on:

  • The significance and reach of their claimed research impact
  • The contribution of their research program to the research impact

NHMRC defines the impact of research as the verifiable outcomes that research makes to knowledge, health, the economy and/or society. Impact is the effect of the research after it has been adopted, adapted for use, or used to inform further research. Research impact is the verifiable outcomes from research and not the prospective or anticipated effects of the research. Research impact also includes research that leads to a decision not to use a particular diagnostic, treatment or health policy.

Engagement and Impact Toolkit

Research Services has developed an Engagement and Impact Toolkit which helps to provide:

  • a comprehensive overview of how research engagement and impact is increasingly influencing researcher practice, institutional strategies and practices as well as research funding;
  • strategies to support research impact at the institutional, faculty and individual level;
  • resources to support data capture and effectively communicate research impact.

A series of tiles on the EI Toolkit homepage link visitors to information and resources across major themes including An introduction to the EI Toolkit, Resources, ARC Engagement and Impact assessment, Promoting your research impact and Collecting EI data.

Citation metrics

One aspect of impact evidence is represented by the recognition of scholarly research outputs. Citation metrics are a significant part of this evidence. Please see the UON Library Guides for a more detailed breakdown of this aspect of research impact.

Research Grants can provide researchers with access to view successful applications where the lead Chief Investigator has provided consent. Applications must be viewed in hard copy in the Research Grants office or by arrangement at HMRI.

How to Arrange to View a Successful Application

Please contact the Research Grants Team to request access to view successful applications for a specific scheme. Please include preferred date(s), time(s) and location.

Presentations

Grant Accelerator Session Recording and Presentations - available via the Research Advantage Resources Hub

Please note a University login is required to access presentation resources

All research projects that are either partially or fully supported by NHMRC funding are required, by the NHMRC Funding Agreement, to appropriately acknowledge the NHMRC contribution to research and other activities in any correspondence, public announcement, advertising material, research report or other material produced for the research project.

The acknowledgement should mention the NHMRC as a funding body, include the Grant Identification Number for the Research Activity and specify that the contents of the published material are solely the responsibility of the research institutions involved or individual authors and do not reflect the views of NHMRC.

Whilst this acknowledgement most often occurs within research outputs, such as journal publications, efforts should also be made if participating in dissemination activities such as conferences or interviews with media outlets.


If you have any questions regarding the Medical Research Future Fund and the current opportunities, please contact the Research Office at research-applications@newcastle.edu.au or call +61 2 4921 7733