Pancreatic Cancer Genome Discovery
Dr Christopher Scarlett from the School of Environmental and Life Sciences is part of a team of scientists from Australia and the United Kingdom who have undertaken an in-depth analysis of 100 pancreatic cancer genomes which has revealed known and newly identified genetic drivers of pancreatic carcinogenesis.
This research, published in Nature, has highlighted four subtypes that may help guide future patient treatment.
Pancreatic cancer is the fifth leading cause of cancer death in Western societies, with a five year survival rate of less than 5%. The treatment and survival of patients with pancreatic cancer has not changed for over thirty years because there has been little research into the molecular and cell biology associated with it. This latest research in Nature allows scientists to view whole genome sequencing globally as a whole, and in more detail at local DNA level.
Find out more
- Read the article in Nature: Whole genomes redefine the mutational landscape of pancreatic cancer
- Read the Garvan Institute article: How the Landscape of the pancreatic cancer genome is coming in to view
- Dr Chris Scarlett's research profile
- Priority Research Centre for Cancer website