The University of Newcastle, Australia

Gene expression profiling of a sarcopenia intervention in older people

Closing Date: 31 July 2018

PhD Scholarship

Our population is aging, which presents a growing problem for the health care system. Aging is associated with changes in body composition, including the development of sarcopenia, or loss of muscle mass. Sarcopenia leads to frailty, reduces quality of life and increases mortality risk. Strategies to avoid sarcopenia are needed to improve health outcomes in older people.

Nutrition, inflammation, aging

We are undertaking an intervention in older people, who have low protein intake and sedentary lifestyle, thus placing them at increased risk of sarcopenia. Our intervention is designed to enhance muscle accretion, by providing two key analbolic stimuli; protein supplementation combined with an exercise intervention. We are assessing the effects of the intervention on body composition, muscle strength and muscle function. In addition, we are examining biological mechanisms that are altered by the intervention. By using microarray gene expression analysis, we will identify muscle synthesis/ inflammatory pathways that are modified by the intervention, thus identifying key therapeutic pathways.

PhD Scholarship details

Stipend (living allowance) of $27,082 p.a. (2018 rate) indexed in January each year. The stipend is offered for a period of 3.5 years.

Supervisor: Prof Lisa Wood

Available to:

Eligibility Criteria

In addition to meeting the admissions criteria and University’s English Proficiency Policy, some experience with laboratory based techniques is required.

Application Procedure

Interested applicants should send an email expressing their interest, including scanned copies of their academic transcripts, CV, a brief statement of their research interests and a proposal that specifically links them to the research project, to by 31 July 2018 at 5pm.

Applications Close 31 July 2018

Contact Prof Lisa Wood
Phone +61 2 4042 0147

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