Drug-Drug Interactions and Cannabis Medicines
Closing Date: 01 November 2019
This project will address the clinical question of if and how prescribed cannabis medicines interact with other prescribed medications.
Cannabis contains many different cannabinoids of which Tetrahydrocannabinol (THC) and Cannabidiol (CBD) have received the most attention. These drugs are reported to be mainly eliminated via metabolism involving CYP450 and UGT enzyme systems. Patients taking cannabis medicines are likely to be co-administered many different medications. Currently there is a paucity of data on potential drug-drug interactions between cannabinoids and commonly used medications. Additionally, few if any data are available on the metabolism of other cannabinoids present in cannabis beyond THC and CBD. This project will investigate metabolism of various cannabinoids using in vitro and in vivo studies to identify potentially significant drug-drug interactions of cannabinoids with other commonly prescribed medications. The project is situated within the Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE), a National Health and Medical Research Council Centre of Research Excellence, the first federally-funded centre for medicinal cannabis research and the University of Newcastle's Centre for Human Drug Research.
This project is lab-based and it is expected to be undertaken onsite in Newcastle, full-time.
PhD Scholarship details
Funding: $27,596 per annum (2019 rate) indexed annually. For a PhD candidate, the living allowance scholarship is for 3.5 years and the tuition fee scholarship is for four years.
Supervisor: Dr Peter Galettis; Associate Professor Jennifer Schneider and Professor Jennifer Martin
Available to: Domestic and International students
In addition to the minimum eligibility criteria, we encourage students with a background in either pharmacy, science, biomedical sciences, biology or biochemistry to apply. The successful candidate cannot commence their study before 1 January 2020 and must commence before 31 August 2020
Interested applicants should send an email expressing their interest along with scanned copies of their academic transcripts, CV, a brief statement of their research interests.
Please send the email expressing interest to Elianne.Renaud@newcastle.edu.au by 5pm on 01 November 2019.
Applications Close 01 November 2019
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