Priority Research Centre for
PHYSICAL ACTIVITY AND NUTRITION
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Clinical and Experimental Nutrition

It is generally advised that people should obtain all essential nutrients by eating natural foods, but in reality it's not always possible, so supplements or functional foods are important alternatives.

The research conducted by researchers in the Clinical and Experimental Nutrition theme of the PRC in PAN examines the role of dietary supplements and fortified foods in weight loss and maintenance, diabetes, asthma, mental health, heart disease and physical activity.


Current Research Programs

Five pronged approach to diabetes and heart disease

Researchers have five new clinical trials concurrently under recruitment in the Hunter, aiming to combat type 2 diabetes and heart disease with an array of natural dietary supplements and tasty foods.

Research Programs
 

PAC-CVD Trial - Phytosterols and curcumin for reducing cardiovascular disease risk

 

PAC-Food Trial - Novel foods enriched with phytosterols and curcumin for heart health benefits
PAC-CVD Clinical Trial

  β-GAPS Trial - β-Glucan and phytosterols for attenuation of cardiovascular disease risk: a randomised control trial
CALFOR-CVD Trial 
- Curcumin and long chain omega 3 fatty acids for management of cardiovascular disease in individuals with  type 2 Diabetes
- Postprandial effects of curcumin with or without omega-3PUFA on insulin resistance and risk of type 2  diabetes
  Metabolic effects of cross-sex hormone treatment in transgender individuals
Saturated fats of variable chain length and cardio-metabolic health
  Cognition Study - association between plasma phospholipid omega-3 polyunsaturated fatty acids and cognitive measures in older people
  COP-D Trial - Combination of curcumin and omega-3PUFA for reducing the risk of diabetes in people wiht pre-diabetes
  O3FA-IR - do omega-3 polyunsaturated fatty acids have a gender specific effect on insulin resistance? A double blind randomised control trial
O3 FA-IR Trial
  Omega-3 fish oil for the prevention of gestational diabetes: A double-blind randomised controlled trial
  Lipemic load - criteria for grading foods and meals based on postprandial triglyceride kinetics
  Glycogen synthase kinase 3 (GSK-3) as a target for reducing the risk of Alzheimer's Disease in people with pre-diabetes

Selected Publications

AltmetricsCitation
Article has an altmetric score of 24
Thota RN, Abbott KA, Ferguson JJA, Veysey M, Lucock M, Niblett S, et al., 'InsuTAG: A novel physiologically relevant predictor for insulin resistance and metabolic syndrome.', Scientific reports, 7 15204 (2017) [C1] DOI 10.1038/s41598-017-15460-z
Article has an altmetric score of 16
Ferguson JJA, Stojanovski E, MacDonald-Wicks L, Garg ML, 'Curcumin potentiates cholesterol-lowering effects of phytosterols in hypercholesterolaemic individuals. A randomised controlled trial', Metabolism: Clinical and Experimental, 82 22-35 (2018) [C1] DOI 10.1016/j.metabol.2017.12.009
Article has an altmetric score of 2
Abbott KA, Burrows TL, Thota RN, Acharya S, Garg ML, 'Do v-3 PUFAs affect insulin resistance in a sex-specific manner? A systematic review and meta-analysis of randomized controlled trials', American Journal of Clinical Nutrition, 104 1470-1484 (2016) [C1] DOI 10.3945/ajcn.116.138172
Article has an altmetric score of 26
Dias CB, Moughan PJ, Wood LG, Singh H, Garg ML, 'Postprandial lipemia: Factoring in lipemic response for ranking foods for their healthiness', Lipids in Health and Disease, 16 1-11 (2017) [C1] DOI 10.1186/s12944-017-0568-5
Article has an altmetric score of 12
Dias CB, Garg R, Wood LG, Garg ML, 'Saturated fat consumption may not be the main cause of increased blood lipid levels', Medical Hypotheses, 82 187-195 (2014) [C1] DOI 10.1016/j.mehy.2013.11.036