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Professor Vanessa McDonald

Professor

School of Nursing and Midwifery (Nursing)

Rethinking chronic lung disease

Falling under the umbrella term of 'multidimensional assessment and individualised management,' Professor Vanessa McDonald's clinical research is helping to engineer a shift in the way patients with long-term respiratory problems are diagnosed and treated.

Associate Professor Vanessa McDonald

By all measures, McDonald is a prolific performer. Though just a few years out of her doctoral studies, the early career researcher has already procured a number of competitive grants, fellowships and scholarships, as well as a publication catalogue worthy of senior academics. She's also achieved marked success closer to home, winning the Vice-Chancellor's Researcher of the Year Award for 2014.

For a long time however, this wasn't the plan. McDonald took an unusual academic pathway to get to where she is at the Hunter Medical Research Institute, spending years as a clinical nurse consultant in respiratory medicine before deciding to undertake a PhD in the late 2000s.

'It was this first role that inspired the second one,' she reveals.

'Problems with approaches to management sparked my research interest in patients with lung disease.'

Still working clinically to 'maintain creativity and currency in terms of generating research ideas,' the esteemed educator and investigator is a master of many trades. She's working with and for patients suffering from complex respiratory conditions in all of these endeavours, focusing principally on chronic obstructive pulmonary disease (COPD), and the overlap of asthma and COPD in older populations, and bronchiectasis. McDonald is also especially interested in advancing care options for those with severe asthma.

There's a small group of patients with severe asthma who are refractory to treatment – we can throw as much traditional asthma medication at them as we like, but they're not going to respond.

'These are the people who have a huge but often preventable healthcare burden, yet little research has been done on management approaches for them.'

McDonald is examining respiratory problems from multiple perspectives in her research, concentrating on the pathophysiological components, functional and psychosocial needs of individual patients. This inventive quadrant approach, which encompasses comorbidity, risk factors, self-management and management of the airways, similarly serves to improve outcomes and help translate findings into scalable and fundable practice.

'Most clinical trials tend to recruit people with pure asthma for asthma studies, and pure COPD for COPD studies, but in the real world when we sit down with a patient, often their diagnosis is impure,' she explains.

'There's usually overlap.'

'Clinical trials generate evidence that informs us on how to manage health conditions, but due to strict inclusion and exclusion criteria they often don't translate to the person sitting in front of us.'

All angles

McDonald characterised asthma and COPD overlap in the older person during her PhD candidature, focusing on the 'usually excluded' population with support from a National Health and Medical Research Council Centre for Respiratory and Sleep Medicine Scholarship. This research area involved collecting data from several sources to inform an intervention for a randomised control trial.

'I undertook qualitative analyses to develop insight into patient needs and healthcare experiences, as well as a cross-sectional study to understand what the population looks like,' she states.

'I then developed an intervention that was piloted in a clinical trial.'

This multidimensional assessment and individualised management study delivered targeted treatments to the individual problems identified, including inflammatory phenotypes, comorbidities and risk factors.

'For example if participants had airway inflammation, the pharmacotherapy was individualised to that phenotype,' she advises.

'If they showed signs of anxiety or depression they underwent cognitive behaviour therapy, and if they were nicotine-dependent they underwent a smoking intervention.'

With results deemed 'quite outstanding' in terms of their impact on health status, McDonald's PhD was published in a top respiratory journal, Thorax, in early 2013.

'The findings demonstrated an improvement in health status that were three times the minimally clinically important difference,' she asserts.

'The intervention also improved the inflammatory processes and the number of exacerbations the patients experienced.'

The principal researcher in the University of Newcastle's Priority Research Centre for Asthma and Respiratory Disease has since followed up on this research, undertaking new studies to see whether the model is transferrable to a 'generally younger' severe asthma population.

A closer look at COPD

McDonald is continuing to develop a large and impressive body of work out of her PhD thesis.  She's the current recipient of the Lung Foundation of Australia's Research Fellowship, awarded annually to one academic from any medical, scientific or allied health background, and is currently using it to fund a study on medication options for patients with COPD.

'We are examining the inflammatory phenotypes of individual patients and targeting pharmacotherapy to these processes,' she clarifies.

'Drugs are used to control eosinophilic and neutrophilic airway inflammation.'

'Medication typically used in cardiovascular diseases, but which we know reduces the degree of systemic inflammation and improves outcomes in COPD, are also being used.'

The co-convenor of the Thoracic Society Australia and New Zealand Special Interest Group has devised a randomised control trial to test this approach, with the intervention group receiving active drugs to match their number of inflammatory phenotypes, and the control group receiving a placebo. Having established a national profile and an emerging international profile, McDonald is also evaluating the health status assessment of COPD patients with St George's London Hospital Professor of Medicine, Paul Jones.

In another offshoot of her PhD, McDonald is undertaking evaluations of a weight loss trial in COPD patients.

'We know that obesity has deleterious health effects, but there's an interesting paradox that exists in COPD where obese patients have better survival than those who are normal or underweight or even just a little overweight,' she discloses.

'It could be that maintenance of muscle mass plays a key role in this, though we're not certain.'

'At present there are no treatment recommendations for this population and advising COPD patients to lose weight could actually be doing harm.'

Coupled with a resistance-training program, the weight loss intervention was found to be successful in both achieving weight loss and maintaining muscle mass. It also resulted in improvements in health status, lung function and ability to carry out daily tasks.

'This pilot study is a proof of concept,' she explains.

'Now we're publishing the data and looking at obtaining an external grant to conduct a larger study and test its true efficacy.'

The energetic academic is simultaneously involved in several current and interdisciplinary collaborations. She's working on a national University of Adelaide-led study on opioids and their potential to improving the exercise capacity of COPD patients within pulmonary rehabilitation programs, and with Laureate Professor Rob Sanson-Fisher from Public Health on a grant for a COPD self-management intervention using online tools.

An equity imperative

Observing 'limited evidence' for COPD treatment guidelines and recommendations for the management of comorbidity, McDonald is also supervising a PhD student to better understand the disease and its comorbidities.

'There's a whole gamut – obesity, anxiety and depression, skeletal muscle dysfunction, and cardiovascular disease,' she declares.

'So we're looking at measurement tools, comorbidity mechanisms, how they relate with each other and their impact on outcomes.'

'This will help us develop novel approaches to comorbidity management in COPD.'

Juggling many projects at once, McDonald and her colleagues are developing a new research area with another PhD student. This time around, the team is exploring sedentary behaviours in people with severe asthma and bronchiectasis.

McDonald is in the process of recruiting patients for the study, which aims to get snapshots of severe asthma and bronchiectasis by 'objectively measuring' how much sufferers exercise throughout the day and how much of the time they are sedentary. The Australian Pulmonary Rehab Guidelines Committee member will then relate data collected from the individual activity monitors to disease phenotypes and outcomes, such as inflammation and health status.

Recognising the futility of applying general population interventions to people with bronchiectasis and severe asthma, McDonald's team will use all of this information to develop and trial a tailor-made behavioural change intervention.

'We want patients to be more active, but we also need to accept that they're often limited by breathlessness, muscle wasting and other comorbid factors.'

Beyond the here and now

Similarly recognising the futility of only undertaking short-term research in this field, McDonald is leading a longitudinal study of patients with bronchiectasis.

'There are few long-term data of this population and determinants of decline,' she admits.

'So I'm following up patients every year for five years to track their progress.'

More recently, McDonald was part of the team that received a $2.5 million National Health and Medical Research Council grant to establish a Centre of Research Excellence in Severe Asthma. It's part of a collaboration led by Professor Peter Gibson involving national researchers from Brisbane, Sydney, Melbourne, and Perth.

'We will seek to improve knowledge of severe asthma and its management and focus on training a new group of severe asthma researchers,' she conveys.

'We will also develop an implementation framework to translate this new knowledge into practice.'

Associate Professor Vanessa McDonald

Rethinking chronic lung disease

Associate Professor Vanessa McDonald is examining respiratory problems from multiple perspectives, concentrating on the pathophysiological components, function

Read more

Career Summary

Biography

Professor Vanessa McDonald is co-director of the NHMRC CRE in Severe Asthma, deputy director and research leader in the Priority Research Centre for Healthy Lungs and an academic clinician in the Department of Respiratory and Sleep Medicine. She also leads the Chronic Disease and Older Person Research group within the School of Nursing and Midwifery.

Professor McDonald joined the University of Newcastle in 2011, following the completion of her PhD.  Prior to this, she worked clinically within the Hunter New England Local Health District as a Respiratory Clinical Nurse Consultant.  She has been a nurse for over 20 years and it is her clinical background and experience that drives her innovation in research.  

Vanessa’s research programme is centred around the development of innovative approaches to the management of chronic diseases.  Her translational research programme links biomedicine, clinical effectiveness and health policy development.   

At 6 years post-doctoral, Professor Vanessa McDonald has established a productive track record publishing over 80 peer reviewed journal articles.  Her work is published in high impact journals including the Lancet, the AJRCCM, Thorax and the Eur Resp J.  Complimenting her publication catalogue is a suite of other outputs. She has authored 7 book chapters, 5 separate national clinical practice guidelines for asthma and COPD, national reports, multimedia resources, and national patient education publications.


Qualifications

  • PhD (Medicine), University of Newcastle
  • Diploma in Health Science (Nursing), University of Newcastle
  • Bachelor of Nursing, University of Newcastle

Keywords

  • Asthma
  • COPD
  • Chronic Disease Management
  • Clinical Management
  • Cystic Fibrosis
  • Nursing
  • Obstructive Airways Disease
  • Older People
  • Self Management
  • Severe Asthma

Fields of Research

Code Description Percentage
110203 Respiratory Diseases 70
111099 Nursing not elsewhere classified 30

Professional Experience

UON Appointment

Title Organisation / Department
Professor University of Newcastle
School of Nursing and Midwifery
Australia

Academic appointment

Dates Title Organisation / Department
1/04/2014 -  Committee Member - COPD Evaluation Committee The Lung Foundation of Australia
Australia
1/01/2014 -  Writing Committee Member The Lung Foundation of Australia
Australia
1/07/2013 -  Writing Committee Member Therapeutic Guidelines - Respiratory
Australia
1/06/2013 - 1/06/2015 Fellow University of Newcastle
School of Nursing and Midwifery
Australia
1/03/2013 -  Co-Convenor - COPD SIG The Thoracic Society of Australia and New Zealand
Australia
1/01/2013 -  Membership - American Thoracic Society American Thoracic Society
United States
1/03/2011 -  Membership - Research subcommittee The Thoracic Society of Australia and New Zealand
Australia
1/04/2007 -  Committee Member - National COPD Coordinating Committee The Lung Foundation of Australia
Australia
1/01/2007 -  Membership - European Respiratory Society European Respiratory Society
United Kingdom
1/01/2000 -  Clinical Nurse Consultant John Hunter Hospital, Newcastle
Australia
1/01/2000 -  Membership - Thoracic Society of Australia and New Zealand Thoracic Society of Australia and New Zealand

Membership

Dates Title Organisation / Department
1/01/2015 - 22/12/2017 APSR International Conference Local Organising Committee The Thoracic Society of Australia and New Zealand
Australia

Professional appointment

Dates Title Organisation / Department
22/08/2015 - 22/09/2015 American Thoracic Society Nursing Assembly Programme Committee American Thoracic Society
United States
1/01/2015 - 23/12/2015 NHMRC Grant Review Panel Member NHMRC (National Health & Medical Research Council)

Awards

Award

Year Award
2014 Vice Chancellor's Award for Research Excellence
The University of Newcastle
2014 The University of Newcastle Researcher of the Year
The University of Newcastle

Distinction

Year Award
2017 Fellow of the Thoracic Society of Australia and New Zealand
The Thoracic Society of Australia & New Zealand
2017 Honorary Visiting Professor Sichuan University
Sichuan University, China
1998 Hunter Valley Chapter Prize
Unknown

Prize

Year Award
2016 Asthma Australia Mid Career Travel Award
Asthma Australia

Research Award

Year Award
2014 TSANZ Dr Janet Elder International Travel Award
Thoracic Society of Australia and New Zealand
2013 Japanese Respiratory Society Early Career Development Awards
Unknown
2013 HMRI EARY CAREER RESEARCHER
Hunter Medical Research Institute
2012 Best COPD Oral Presentation
Thoracic Society of Australia and New Zealand
2012 The Dr Janet Elder International Travel Award
Thoracic Society of Australia and New Zealand
2011 Best Oral Presentation - TSANZ COPD Award
Thoracic Society of Australia and New Zealand
2011 Pulse Early Career Research Prize
Unknown
2008 Best Oral Presentation - Nrurses Award
Thoracic Society of Australia and New Zealand
2002 Best Oral Presentation - Nurses Award
Thoracic Society of Australia and New Zealand
2000 Best Poster Presentation - Nurses Award
Thoracic Society of Australia and New Zealand
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Grants and Funding

Summary

Number of grants 42
Total funding $5,234,061

Click on a grant title below to expand the full details for that specific grant.


Highlighted grants and funding

National Clinical Centre of Research Excellence in Severe Asthma$2,448,108

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Professor Guy Marks, Professor Vanessa McDonald, Conjoint Professor Peter Wark, Conjoint Associate Professor Greg King, Dr Bruce Thompson, Associate Professor Helen Reddel, Professor John Upham, Dr Lorraine Smith, Professor Alan James
Scheme Centres of Research Excellence (CRE) - Centres of Clinical Research Excellence
Role Investigator
Funding Start 2014
Funding Finish 2019
GNo G1400017
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

20177 grants / $1,017,100

Targeting neutrophil extracellular traps to reduce inflammation in severe asthma$590,463

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Katie Baines, Conjoint Professor Peter Gibson, Professor Jodie Simpson, Professor Dominik Hartl, Professor Vanessa McDonald
Scheme Project Grant
Role Investigator
Funding Start 2017
Funding Finish 2019
GNo G1500231
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Asthma and COPD Endotypes (ACE) - the impact of eosinophils$177,840

Funding body: AstraZeneca

Funding body AstraZeneca
Project Team Professor Vanessa McDonald, Conjoint Professor Peter Gibson
Scheme Research Grant
Role Lead
Funding Start 2017
Funding Finish 2019
GNo G1700651
Type Of Funding International - Non Competitive
Category 3IFB
UON Y

Severe Asthma Treatable Traits Respiratory Research Fellowship$100,000

Funding body: GlaxoSmithKline Australia

Funding body GlaxoSmithKline Australia
Project Team Professor Vanessa McDonald, Conjoint Professor Peter Gibson
Scheme Support Grant
Role Lead
Funding Start 2017
Funding Finish 2018
GNo G1700681
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Imaging treatable traits$99,797

Funding body: Cyclopharm Limited

Funding body Cyclopharm Limited
Project Team Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Doctor Natalie Rutherford, Conjoint Professor Peter Wark, Conjoint Associate Professor Christopher Grainge
Scheme Research Grant
Role Lead
Funding Start 2017
Funding Finish 2017
GNo G1700386
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Patient Reported Outcome Measure in Severe Asthma (PROMISe): A New Tool That Measures Severe Asthma’s Impact on Quality of Life$20,000

Funding body: John Hunter Hospital Charitable Trust

Funding body John Hunter Hospital Charitable Trust
Project Team Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Professor Janelle Yorke, Dr Robert Niven, Professor Paul Jones
Scheme Research Grant
Role Lead
Funding Start 2017
Funding Finish 2017
GNo G1700328
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Patient Reported Outcome Measure in Severe Asthma (PROMISe): A New Tool That Measures Severe Asthma’s Impact on Quality of Life$20,000

Funding body: National Clinical CRE in Severe Asthma

Funding body National Clinical CRE in Severe Asthma
Project Team Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Professor Janelle Yorke, Dr Robert Niven, Professor Paul Jones
Scheme Seed Research Project
Role Lead
Funding Start 2017
Funding Finish 2017
GNo G1700346
Type Of Funding Internal
Category INTE
UON Y

CoreScan Software - Dual Energy X-ray absorptiometry machine$9,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Bronwyn Berthon, Professor Lisa Wood, Doctor Katie Baines, Professor Vanessa McDonald
Scheme Early and Mid-Career Equipment Grant
Role Investigator
Funding Start 2017
Funding Finish 2017
GNo G1701222
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20165 grants / $268,158

Targeted Management in Severe Asthma$178,158

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Vanessa McDonald
Scheme Translating Research into Practice (TRIP) Fellowships
Role Lead
Funding Start 2016
Funding Finish 2017
GNo G1500640
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

CELL-DYN Ruby Hematology Analyser (Abbott Haemotology)$30,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Professor Jodie Simpson, Conjoint Professor Peter Wark, Professor Lisa Wood, Doctor Vanessa Murphy
Scheme Equipment Grant
Role Lead
Funding Start 2016
Funding Finish 2016
GNo G1601306
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Development and Validation of the First Patient Reported Outcome Measure in Severe Asthma (PROMISe)$20,000

Funding body: National Clinical CRE in Severe Asthma

Funding body National Clinical CRE in Severe Asthma
Project Team Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Professor Janelle Yorke
Scheme Seed Research Project
Role Lead
Funding Start 2016
Funding Finish 2016
GNo G1600921
Type Of Funding Internal
Category INTE
UON Y

Managing Inflammation in COPD (MiCOPD)$20,000

Funding body: Lung Foundation Australia

Funding body Lung Foundation Australia
Project Team Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Professor Jodie Simpson, Conjoint Professor Peter Wark
Scheme Boehringer Ingelheim COPD Research Top-Up Grant
Role Lead
Funding Start 2016
Funding Finish 2017
GNo G1601013
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Inflammation based management of severe asthma: utility of blood oesinophils$20,000

Funding body: National Clinical CRE in Severe Asthma

Funding body National Clinical CRE in Severe Asthma
Project Team Conjoint Professor Peter Wark, Professor Jodie Simpson, Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Conjoint Associate Professor Christopher Grainge
Scheme Seed Research Project
Role Investigator
Funding Start 2016
Funding Finish 2016
GNo G1601079
Type Of Funding Internal
Category INTE
UON Y

20155 grants / $49,222

Physical Inactivity and Sedentary Behaviour in Severe Asthma: the new smoking.$25,222

Funding body: John Hunter Hospital Charitable Trust

Funding body John Hunter Hospital Charitable Trust
Project Team Professor Vanessa McDonald, Mrs Laura Cordova Rivera, Emeritus Professor Michael Hensley, Dr Paul Gardiner
Scheme Research Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1500112
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Research of the year Award$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Vanessa McDonald
Scheme Award for Research Excellence
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1401521
Type Of Funding Internal
Category INTE
UON Y

(PROJECT)$10,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Vanessa McDonald, Mrs Netsanet Negewo, Conjoint Professor Peter Gibson, Doctor Katie Baines
Scheme Jennie Thomas Medical Research Travel Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1501430
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

2014 Vice Chancellors Award for Research Excellence - Faculty of Medicine and Health$2,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Vanessa McDonald
Scheme Award for Research Excellence
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1401477
Type Of Funding Internal
Category INTE
UON Y

American Thoracic Society, Colorado USA, 15-20 May 2015$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Professor Vanessa McDonald
Scheme Travel Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1500738
Type Of Funding Internal
Category INTE
UON Y

20147 grants / $2,574,211

National Clinical Centre of Research Excellence in Severe Asthma$2,448,108

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Professor Guy Marks, Professor Vanessa McDonald, Conjoint Professor Peter Wark, Conjoint Associate Professor Greg King, Dr Bruce Thompson, Associate Professor Helen Reddel, Professor John Upham, Dr Lorraine Smith, Professor Alan James
Scheme Centres of Research Excellence (CRE) - Centres of Clinical Research Excellence
Role Investigator
Funding Start 2014
Funding Finish 2019
GNo G1400017
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

The experiences and perceptions of people living with severe asthma. $42,000

Funding body: Asthma Australia

Funding body Asthma Australia
Project Team

Juliet Foster

Scheme Unrestricted research grant
Role Investigator
Funding Start 2014
Funding Finish 2016
GNo
Type Of Funding External
Category EXTE
UON N

Investigating the Phenotypes of Bronchiectasis$27,512

Funding body: John Hunter Hospital Charitable Trust

Funding body John Hunter Hospital Charitable Trust
Project Team Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Mrs Netsanet Negewo
Scheme Research Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1400084
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

The role of comorbidities and inflammation in Chronic Obstructive Pulmonary Disease (COPD)$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Mrs Netsanet Negewo, Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Doctor Katie Baines
Scheme Postgraduate Research Scholarship
Role Lead
Funding Start 2014
Funding Finish 2015
GNo G1401393
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Predicting who is at risk of worsening lung disease in Cystic Fibrosis$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Conjoint Professor Peter Wark, Doctor Katie Baines, Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Associate Professor Scott Bell, Associate Professor David Reid
Scheme Project Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1401410
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

PULSE Early Career Researcher of the Year$14,591

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Vanessa McDonald
Scheme PULSE Early Career Researcher of the Year Award
Role Lead
Funding Start 2014
Funding Finish 2017
GNo G1301332
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

TSANZ Annual Scientific Meeting, Adelaide AUS, 4-9 April 2014$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Professor Vanessa McDonald
Scheme Travel Grant
Role Lead
Funding Start 2014
Funding Finish 2015
GNo G1400090
Type Of Funding Internal
Category INTE
UON Y

20135 grants / $988,380

Inflammometry in Stable COPD; A Randomised Controlled Trial (RCT)$743,351

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Professor Vanessa McDonald, Professor Jodie Simpson, Conjoint Professor Peter Wark
Scheme Project Grant
Role Investigator
Funding Start 2013
Funding Finish 2016
GNo G1200185
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Managing Inflammatory Phenotypes in Stable COPD: A Randomised Control Trial$160,000

Funding body: Lung Foundation Australia

Funding body Lung Foundation Australia
Project Team Professor Vanessa McDonald
Scheme Boehringer Ingelheim Chronic Obstructive Pulmonary Disease Research Fellowship
Role Lead
Funding Start 2013
Funding Finish 2014
GNo G1300813
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Managing Inflammatory Phenotypes in COPD$74,929

Funding body: Ramaciotti Foundations

Funding body Ramaciotti Foundations
Project Team Professor Vanessa McDonald
Scheme Establishment Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1200730
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

36 GT3XPlus – Wireless Triaxial Activity Monitors, with Actilife 6 software – 1 licence for 6 monitors, soft heart rate straps and elastic belts for attachment$8,100

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Vanessa McDonald
Scheme Equipment Grant
Role Lead
Funding Start 2013
Funding Finish 2014
GNo G1301309
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

TSANZ Annual Scientific Meeting, Darwin Convention Centre, 23 - 27 March 2013$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Professor Vanessa McDonald
Scheme Travel Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300179
Type Of Funding Internal
Category INTE
UON Y

20122 grants / $54,454

Phenotype based management of severe persistent asthma$34,454

Funding body: John Hunter Hospital Charitable Trust

Funding body John Hunter Hospital Charitable Trust
Project Team Professor Vanessa McDonald, Doctor Katie Baines, Conjoint Professor Peter Gibson
Scheme Research Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1200211
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Phenotype based management of severe persistent asthma$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Vanessa McDonald, Doctor Katie Baines, Conjoint Professor Peter Gibson
Scheme Research Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1101169
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20112 grants / $14,337

Phenotype based management of severe persistent asthma$10,337

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Vanessa McDonald
Scheme Early Career Researcher Grant
Role Lead
Funding Start 2011
Funding Finish 2011
GNo G1101050
Type Of Funding Internal
Category INTE
UON Y

PULSE Education Prize$4,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Vanessa McDonald
Scheme PULSE Education Prize
Role Lead
Funding Start 2011
Funding Finish 2011
GNo G1100817
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20101 grants / $25,000

Investigating the Obesity Paradox in COPD$25,000

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team

Vanessa McDonald

Scheme Research Grant
Role Lead
Funding Start 2010
Funding Finish 2011
GNo
Type Of Funding Other Public Sector - Local
Category 2OPL
UON N

20092 grants / $53,286

Development of an interactive DVD for COPD$35,000

Funding body: Department of Veterans` Affairs

Funding body Department of Veterans` Affairs
Project Team

Vanessa McDonald

Scheme Innovative Funding Projects
Role Lead
Funding Start 2009
Funding Finish 2011
GNo
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON N

Integrated Problem Based Management (IPBM) of Obstructive Airways Disease in Older People (OAD) $18,286

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team

Vanessa McDonald

Scheme Research Grant
Role Lead
Funding Start 2009
Funding Finish 2010
GNo
Type Of Funding Other Public Sector - Local
Category 2OPL
UON N

20081 grants / $15,208

Management of Obstructive Airways Disease in Older People$15,208

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team

Vanessa McDonald

Scheme Research Grant
Role Lead
Funding Start 2008
Funding Finish 2009
GNo
Type Of Funding Other Public Sector - Local
Category 2OPL
UON N

20074 grants / $148,195

PhD Scholarship$88,595

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team

Vanessa McDonald

Scheme Centres of Research Excellence (CRE) - Centres of Clinical Research Excellence
Role Lead
Funding Start 2007
Funding Finish 2010
GNo
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON N

Nitric Oxide Monitoring System (NIOX)$45,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Conjoint Associate Professor Vicki Clifton, Conjoint Professor Warwick Giles, Emeritus Professor Michael Hensley, Doctor Vanessa Murphy, Conjoint Professor Peter Wark, Professor Vanessa McDonald, Professor Jodie Simpson, Conjoint Associate Professor Bruce Whitehead, Laureate Professor Paul Foster, Professor Phil Hansbro, Professor Lisa Wood
Scheme Equipment Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0188193
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

A model of care for a patient centred multi disciplinary problem based approach to airways disease in the elderly$9,600

Funding body: NSW Health

Funding body NSW Health
Project Team

Vanessa McDonald

Scheme Innovations Grant
Role Lead
Funding Start 2007
Funding Finish 2008
GNo
Type Of Funding Other Public Sector - State
Category 2OPS
UON N

A Problem Based Approach to the Management of Airways Disease in people over the age of 55 years$5,000

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team

Vanessa McDonald

Scheme Research Grant
Role Lead
Funding Start 2007
Funding Finish 2008
GNo
Type Of Funding Other Public Sector - Local
Category 2OPL
UON N

20061 grants / $26,510

The role of respiratory virus infection in CF lung disease$26,510

Funding body: Australian Cystic Fibrosis Research Trust

Funding body Australian Cystic Fibrosis Research Trust
Project Team

Peter Wark

Scheme Cystic Fibrosis Research Grant
Role Investigator
Funding Start 2006
Funding Finish 2008
GNo
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON N
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Research Supervision

Number of supervisions

Completed5
Current7

Total current UON EFTSL

Masters0.4
PhD2.3

Current Supervision

Commenced Level of Study Research Title Program Supervisor Type
2017 PhD Characteristics of the Airway¿Systemic Innate Inflammation Axis in COPD and Severe Asthma PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2016 Masters Investigation of Vitamin D¿s Significance to Severe Cardiovascular Disease M Philosophy (Nursing), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2016 PhD Sleep Disturbance in Dialysis Patients PhD (Nursing), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2016 PhD Assessment and Management of Clinically Severe Obese Older People with Respiratory Co-morbidities PhD (Nursing), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2015 PhD Prescription of acute oxygen therapy in patients at risk of type 11 respiratory failure PhD (Nursing), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2015 Masters An exploration of the diagnostic journey of children with Neuronal Ceroid Lipofuscinosis (NCL) M Philosophy (Nursing), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2014 PhD Physical Activity and Sedentary Behaviour in Obstructive Airway Diseases PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor

Past Supervision

Year Level of Study Research Title Program Supervisor Type
2017 Honours Advancing Precision-Medicine in Chronic Obstructive Pulmonary Disease (COPD): Biomarkers in clinical phenotypes and inflammatory endotypes Biological Sciences, Priority Research Centre (PRC) for Healthy Lungs | The University of Newcastle Principal Supervisor
2017 Honours Advancing Precision-Medicine in Chronic Obstructive Pulmonary Disease (COPD): Biomarkers in clinical phenotypes and inflammatory endotypes Biological Sciences, Priority Research Centre (PRC) for Healthy Lungs | The University of Newcastle Principal Supervisor
2017 PhD The Role of Comorbidities and Inflammation in COPD PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2014 PhD Systemic Inflammation in Obstructive Airway Disease PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2014 Honours Evaluation of a weight loss intervention in obese COPD Nutrition & Dietetics, The University of Newcastle Co-Supervisor
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News

Leading respiratory nursing researcher awarded TSANZ Fellowship

March 29, 2017

Professor Vanessa McDonald is the first and only nurse to have been awarded the title of Fellow of the Thoracic Society of Australia and New Zealand (FThorSoc) for her excellence in respiratory health research.

Associate Professor Vanessa McDonald

Weight-loss study challenges COPD’s obesity puzzle

February 29, 2016

Faced with a clinical paradox where obesity seemingly offers a protective effect for Chronic Obstructive Pulmonary Disease (COPD), Hunter researchers have performed a world-first pilot study aimed at achieving weight loss without exacerbating respiratory symptoms.

VC's Awards 2014

Vice-Chancellor's Awards Winners

December 9, 2014

Each year the University of Newcastle celebrates the remarkable achievements of our staff at the Vice-Chancellor's Awards ceremony.

Vanessa McDonald

World COPD Day

November 19, 2013

Hunter Medical Research Institute respiratory researchers will offer free lung function tests and information sessions for members of the public to mark World COPD Day on Wednesday, November 19.

Phil Hansbro

HMRI 2013 Awards Night

November 7, 2013

Respiratory researcher Professor Phil Hansbro won the prestigious 2013 Award for Research Excellence tonight as more than $1.4 million in grant funding was awarded and acknowledged in the Hunter Medical Research Institute's 2013 Awards Night.

Professor Vanessa McDonald

Position

Professor
School of Nursing and Midwifery
Faculty of Health and Medicine

Focus area

Nursing

Contact Details

Email vanessa.mcdonald@newcastle.edu.au
Phone (02) 40420146
Fax (02) 4042 0046

Office

Room Level 2 West Wing
Building Hunter Medical Research Institute
Location Lot 1, Kookaburra Circuit New Lambton Heights NSW 2305 HMRI Mailing Address: Locked Bag 1000 New Lambton NSW 2305

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