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Professor Manohar Garg

Professor

School of Biomedical Sciences and Pharmacy (Pharmacy and Experimental Pharmacology)

Accolades abounds

Professor Manohar Garg is one of the University's leading Health and Nutrition researchers and has recently been heralded as a revolutionary in his field with two important industry honours.

Professor Manohar Garg in the fruit shop 

In November 2012, Professor Garg was awarded the 2012 Nutrition Society of Australia Medal. This medal is awarded to an Australian nutrition scientist with an outstanding record in the field of animal or human nutrition.

"This medal is presented on the basis of overall research performance," said Professor Garg.

"My research has had an important impact on human health but this award was also measured on the overall impact of my research including quality and quantity of research publications, links with stakeholders including those in the industry, supervision of Research Higher Degree students and contributions to the Activities of the Nutrition Society of Australia."

Professor Garg was also awarded the prestigious 2012 Professor Austin Doyle Medal. This honour is in recognition of his outstanding contributions in cardiovascular sciences, especially the role of nutrition in preventing complications of cardiovascular disease.

"My research on long chain omega-3 fatty acids and sex-based responses of nutrition interventions on cardiovascular disease acclaimed world-wide attention.

Professor Manohar Garg receiving the 2012 Nutrition Society of Australia Medal"This award is a good reinforcement that what I am doing has not only benefited many people, but it is also valued amongst the industry and colleagues," he said.

This medal was presented at the 22nd Annual Scientific Meeting of the Indian Society of Hypertension, where as part of the honour Professor Garg also delivered the Professor Austin Doyle Oration.

Austin Doyle was the President of the International Society of Hypertension and had a profound impact on hypertension research, first in Australia, and ultimately worldwide. The award was named in his honour.

For more information on Manohar's work see the Centre for Physical Activity and Nutrition.

Professor Manohar Garg in the fruit shop

Accolades abounds

Professor Manohar Garg is one of the University's leading Health and Nutrition researchers and has recently been heralded as a revolutionary in his field with two important industry honours.

Read more

Career Summary

Biography

Research Expertise
- Anti-oxidant effects of food constituents - Role of dietary fats & oils in human health & disease - Safety and efficacy of functional foods, nutraceuticals and dietary supplements - Anti-inflammatory effects of food constitutents - Development of novel nutraceuticals for improvement of human health

Qualifications

  • PhD, University of Adelaide
  • Master of Science (Nutrition & Dietetics), University of Wollongong

Keywords

  • Complementary Medicine
  • Dietary Fats and Oils
  • Functional Foods
  • Lipids
  • Medicinal Chemistry
  • Nutraceuticals
  • Nutrition
  • Nutritional Biochemistry
  • Pharmacetical Chemistry

Languages

  • Hindi (Fluent)
  • Punjabi (Fluent)

Fields of Research

Code Description Percentage
111199 Nutrition and Dietetics not elsewhere classified 55
090899 Food Sciences not elsewhere classified 20
110299 Cardiorespiratory Medicine and Haematology not elsewhere classified 25

Professional Experience

UON Appointment

Title Organisation / Department
Professor University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia

Academic appointment

Dates Title Organisation / Department
1/07/2007 -  Professor & Director University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia
1/01/2003 - 1/06/2007 Associate Professor University of Newcastle
Australia
1/01/1995 - 1/12/2002 Senior Lecturer University of Newcastle
Nutrition and Dietetics
Australia
1/01/1993 - 1/12/1995 Lecturer University of Newcastle
Nutrition and Dietetics
Australia
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Book (2 outputs)

Year Citation Altmetrics Link
2013 Garg ML, Wood LG, Nutrition and Physical Activity in Inflammatory Diseases, CABI, Oxfordshire, 416 (2013) [A3]
Co-authors Lisa Wood
1999 Basu TK, Temple NJ, Garg ML, Antioxidants in Human Health and Disease, CABI International, Oxford UK, 450 (1999) [A3]

Chapter (19 outputs)

Year Citation Altmetrics Link
2016 Singh RB, Singh AK, Mori H, Pella D, Basu TK, Ozimek L, et al., 'In memorium, Shanti S. Rastogi, MBBS, MD, FRCP, FICN, FICC', Chronocardiology and Cardiac Research 363-370 (2016)
2016 Hristova K, Pella D, Singh RB, Dimitrov BD, Chaves H, Juneja L, et al., 'Sofia declaration for prevention of cardiovascular diseases and type 2 diabetes mellitus: A scientific statement of the international college of cardiology and international college of nutrition', Chronocardiology and Cardiac Research 151-175 (2016)

© 2016 Nova Science Publishers, Inc. Background: There has been persistent emphasis from various health agencies including United Nations on the prevention of cardiovascular dise... [more]

© 2016 Nova Science Publishers, Inc. Background: There has been persistent emphasis from various health agencies including United Nations on the prevention of cardiovascular diseases (CVDs) and other chronic diseases. This review focusses on the emergence of CVDs and other chronic diseases as well as on modern strategies for their prevention. Methods: A systematic and narrative review was conducted using such reference databases as MEDLINE (PubMed), Web of Science and EBSCO, with additional secondary sources and grey literature searching. Opinions of experts were also sought and discussions followed. Results: The prevalence of primary risk factors for most chronic diseases is rapidly increasing in low and middle income populations due to the on-going economic development and progress. There is a decrease in such risk factors in the developed countries as due to education and adoption of preventive strategies result in a reduction in CVD mortality. Hypertension (5-10%), type 2 diabetes (3-5%) and CAD (3-4%) are very low in the adult rural populations of India, China, and in the African sub-continent which has less economic development. It seems that it is not poverty, but the lack of health education, possibly due to ineffective policies of national and local governments. In urban and immigrant populations of India and China, which are economically better off, NCDs are significantly higher than they are in some of the high-income populations. Health education and promotion of healthier lifestyle and behaviour appear to be important for prevention in such countries. Conclusion: These findings may require modification of the existing American and European guidelines, proposed for the prevention of CVDs and other chronic diseases, in high-income populations.

2016 Ferguson JJA, Dias CB, Garg ML, 'Omega-3 polyunsaturated fatty acids and hyperlipidaemias', Omega-3 Fatty Acids: Keys to Nutritional Health 67-78 (2016) [B1]

© Springer International Publishing Switzerland 2016. All rights reserved. Hyperlipidaemia is a multifaceted risk factor for cardiovascular disease, involving multiple aetiologie... [more]

© Springer International Publishing Switzerland 2016. All rights reserved. Hyperlipidaemia is a multifaceted risk factor for cardiovascular disease, involving multiple aetiologies such as diet, lifestyle, and/or metabolic effects within the body. Dietary long-chain omega-3 polyunsaturated fatty acids (n-3PUFA) have been shown to regulate key pathways involved in lipid metabolism. By this action, n-3PUFA favourably modulate blood lipids such as triglycerides (TG), low-density lipoproteins (LDL), and high-density lipoproteins (HDL). The hypolipidaemic effects of dietary supplementation with n-3PUFA may be enhanced by combination drug or natural therapies and have the potential to reduce dependence on lipid-lowering drug therapy. The widespread modulatory effects on blood lipid profile are not only dose dependent, but also dependent on genetic make-up and gender differences. Further investigation into the modulatory effects of dietary n-3PUFA on blood lipids is warranted in order to optimize the efficacy of n-3PUFA therapy for the prevention and management of hyperlipidaemias. Future studies should investigate the influence of gender and genotypic variants on the effects of dietary n-3PUFA in order to optimize dietary strategies and recommendations to prevent and manage hyperlipidaemias.

DOI 10.1007/978-3-319-40458-5_6
2015 Thomas J, Garg ML, 'Dietary Long Chain Omega-3 Polyunsaturated Fatty Acids and Inflammatory Gene Expression in Type 2 Diabetes', Molecular Nutrition and Diabetes: A Volume in the Molecular Nutrition Series 291-299 (2015)

© 2016 Elsevier Inc. All rights reserved. In metabolic disorders such as diabetes, which occurs because of compounded factors, inflammation is thought to play a major role in the... [more]

© 2016 Elsevier Inc. All rights reserved. In metabolic disorders such as diabetes, which occurs because of compounded factors, inflammation is thought to play a major role in the pathobiology and deleterious effects of this disease. Pro-inflammatory cytokines such as tumor necrosis factor-a, interleukin-6, and interleukin 1-ß potentially damage micro- and macrovascular circulation, increase cyclooxygenase-2 and prostaglandin E 2 , activate Toll-like receptor 4 and interrupt insulin signaling, leading to insulin resistance by causing adipose dysfunction in diabetes. Omega-3 polyunsaturated fatty acids (PUFAs) have been shown to help lower triglycerides and pro-inflammatory markers and higher omega-3 index, a reliable indicator of omega-3 PUFA status, has been shown to be inversely associated with insulin resistance. Recent studies have demonstrated that omega-3 PUFAs decrease pro-inflammatory gene expression. Although omega-3 PUFAs have been suggested to have anti-inflammatory properties, the exact mechanism by which omega-3 PUFAs mediate anti-inflammatory action are poorly understood. Also, whether hyperglycemia-induced inflammation can be ameliorated by dietary supplementation with n-3 PUFAs remains to be established.

DOI 10.1016/B978-0-12-801585-8.00023-3
2014 Phang M, Garg M, 'Combined Phytosterol and Fish Oil Therapy for Lipid Lowering and Cardiovascular Health', Food Structures, Digestion and Health 437-463 (2014)

© 2014 Elsevier Inc. All rights reserved. Prevention of atherosclerosis and its complications, both primary and secondary, is based primarily on controlling various cardiovascula... [more]

© 2014 Elsevier Inc. All rights reserved. Prevention of atherosclerosis and its complications, both primary and secondary, is based primarily on controlling various cardiovascular risk factors. Treating combined hyperlipidemia with emphasis on reducing LDL cholesterol and triglyceride levels and increasing HDL cholesterol has been established as a highly efficacious means of reducing both morbidity and mortality from cardiovascular disease. Although statins may prove effective in the treatment for hyperlipidemia, they may not be sufficient to achieve the recommended lipid levels, in particular triglyceride goals, as set out by national governing bodies. The lipid-lowering potential of both phytosterols and omega-3 fatty acids has been well documented. Dietary supplementation with phytosterols reduces the circulating concentration of total cholesterol and LDL cholesterol, but without considerable effects on HDL cholesterol or triglycerides. Conversely, a wealth of evidence has demonstrated the triglyceride lowering, as well as anti-aggregatory, anti-inflammatory and anti-arrhythmic, properties of omega-3 fatty acids. Given the propensity of hyperlipidemia to manifest in high risk individuals, there is a plausible case for combining phytosterols and omega-3 fatty acid supplementation in the management and prevention of hyperlipidemia as well as other cardiovascular diseases.

DOI 10.1016/B978-0-12-404610-8.00016-5
Citations Scopus - 3
2013 Garg ML, Wood LG, 'Role of omega-3 fatty acids in weight loss and maintenance', The Omega-3 Fatty Acid Deficiency Syndrome: Opportunities for Disease Prevention, Nova Science, Hauppaugue, NY 233-246 (2013) [B1]
Co-authors Lisa Wood
2013 Scott H, Wood LG, Garg ML, Gibson PG, 'Asthma and Inflammation', Nutrition and Physical activity in inflammatory diseases, CABI, Oxford, UK 299-321 (2013) [B1]
Co-authors Peter Gibson, Hayley Scott, Lisa Wood
2012 Micallef MA, Garg ML, 'Combined supplementation with EPA-rich fish oil and phytosterols improve plasma lipid profile and C-Reactive Protein (CRP) in individuals with hyperlipidemia', Eicosapentaenoic Acid: Sources, Health Effects and Role in Disease Prevention, NOVA Publishers, New York 129-142 (2012) [B1]
2011 Wood LG, Garg ML, 'Macadamia nuts (Macadamia integrifolia and tetraphylla) and their use in hypercholesterolemic subjects', Nuts and Seeds in Health and Disease Prevention, Academic Press, San Diego 717-725 (2011) [B2]
DOI 10.1016/b978-0-12-375688-6.10085-4
Citations Scopus - 2
Co-authors Lisa Wood
2011 Kostrilis V, Garg ML, 'Hyperlipidemia', A Guide to Evidence-based Integrative and Complementary Medicine, Churchill Livingstone Australia, Sydney 444-470 (2011) [B2]
2009 Munro IA, Garg ML, 'Nutrient composition and health beneficial effects of macadamia nuts', Tree Nuts: Composition, Phytochemicals, and Health Effects, CRC Press, Boca Raton 249-258 (2009) [B1]
DOI 10.1201/9781420019391.ch15
2007 Plunkett BA, Callister R, Garg ML, 'Nutraceuticals and inflammation in athletes', Handbook of Nutraceuticals and Functional Foods, CRC Press, Boca Raton 409-420 (2007) [B1]
Co-authors Robin Callister
2007 Watson TA, Callister R, Garg ML, 'Oxidative stress and antioxidant requirements in trained athletes', Handbook of Nutraceuticals and Functional Foods, CRC Press, Boca Raton 421-442 (2007) [B1]
Co-authors Robin Callister
2007 Wood LG, Gibson PG, Garg ML, 'Alpha-tocopherol and cystic fibrosis', The Encyclopedia of Vitamin E, Centre for Agricultural Bioscience International, Wallingford, United Kingdom 708-718 (2007) [B1]
Co-authors Peter Gibson, Lisa Wood
2006 MacDonald-Wicks LK, Garg ML, 'Oxidised LDL and antioxidants in atherosclerosis', Biochemistry of Atherosclerosis, Springer, Berlin 519-541 (2006) [B1]
Co-authors Lesley Wicks
2000 Rudra PK, Nair S, Leitch J, Garg ML, 'Omega-3 Polyunsaturated Fatty Acids and Cardiac Arrhythmias', Handbook of Nutraceuticals and Functional Foods, CRC Press LLC, United States 331-344 (2000) [B1]
2000 Volker DH, Garg ML, 'Omega-3 polyunsaturated fatty acids and rheumatoid arthritis', Handbook of Neutraceuticals and Functional Foods, CRC Press LLC, United States 353-376 (2000) [B1]
1999 Quaggiotto P, Garg ML, 'Isoprostanes: Indicators of Oxidative Stress in Vivo and Their Biological Activity', Antioxidants in Human Health and Disease, CAB International, Oxford UK 393-410 (1999) [B1]
1999 Wood LG, Collins CE, Garg ML, 'Oxidative stress and antioxidants in cystic fibrosis', Antiooxidants in Human Health and Disease, CAB International, Oxford UK 313-333 (1999) [B1]
Co-authors Lisa Wood, Clare Collins
Show 16 more chapters

Journal article (224 outputs)

Year Citation Altmetrics Link
2017 Dias CB, Amigó N, Wood LG, Mallol R, Correig X, Garg ML, 'Improvement of the omega 3 index of healthy subjects does not alter the effects of dietary saturated fats or n-6PUFA on LDL profiles', Metabolism: Clinical and Experimental, 68 11-19 (2017)

© 2016 Background and Aims Dietary fat composition is known to modulate circulating lipid and lipoprotein levels. Although supplementation with long chain omega-3 polyunsaturated... [more]

© 2016 Background and Aims Dietary fat composition is known to modulate circulating lipid and lipoprotein levels. Although supplementation with long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) has been shown to reduce plasma triglyceride levels, the effect of the interactions between LCn-3PUFA and the major dietary fats consumed has not been previously investigated. Methods In a randomized controlled parallel design clinical intervention, we examined the effect of diets rich in either saturated fatty acids (SFA) or omega-6 polyunsaturated fatty acids (n-6PUFA) on plasma lipid levels and lipoprotein profiles (lipoprotein size, concentration and distribution in subclasses) in subjects with an adequate omega 3 index. Twenty six healthy subjects went through a four-week pre-supplementation period with LCn-3PUFA and were then randomized to diets rich in either n-6PUFA or SFA both supplemented with LCn-3PUFA. Results The diet rich in n-6PUFA decreased low density lipoprotein (LDL) particle concentration (-¿8%, p¿=¿0.013) and LDL cholesterol (LDL-C) level (-¿8%, p¿=¿0.021), while the saturated fat rich diet did not affect LDL particle concentration or LDL-C levels significantly. Nevertheless, dietary saturated fatty acids increased LCn-3PUFA in plasma and tissue lipids compared with n-6PUFA, potentially reducing other cardiovascular risk factors such as inflammation and clotting tendency. Conclusion Improvement on the omega 3 index of healthy subjects did not alter the known effects of dietary saturated fats and n-6PUFA on LDL profiles.

DOI 10.1016/j.metabol.2016.11.014
Co-authors Lisa Wood
2017 Goozee K, Chatterjee P, James I, Shen K, Sohrabi HR, Asih PR, et al., 'Alterations in erythrocyte fatty acid composition in preclinical Alzheimer's disease', SCIENTIFIC REPORTS, 7 (2017) [C1]
DOI 10.1038/s41598-017-00751-2
Citations Web of Science - 1
2017 Gallier S, Acton D, Garg M, Singh H, 'Natural and processed milk and oil body emulsions: Bioavailability, bioaccessibility and functionality', Food Structure, 13 13-23 (2017)

© 2016 Elsevier Ltd A well-studied naturally-occurring lipid structure is the oil-in-water emulsion droplet. The interfacial quality and quantity of the oil droplets play a key r... [more]

© 2016 Elsevier Ltd A well-studied naturally-occurring lipid structure is the oil-in-water emulsion droplet. The interfacial quality and quantity of the oil droplets play a key role in the digestion in the gut and subsequent lipid uptake and may have longer term health consequences. Studies on natural droplets, the milk fat glob ules and the oil bodies, and the effect of processing on their structure and on their digestion are discussed. This article reviews how processing affects the structure of naturally-occurring oil droplets, how it impacts the lipid bioavailability and bioaccessibility, and highlights recent developments to mimic natural lipid emulsion functionality for infant nutrition.

DOI 10.1016/j.foostr.2016.07.005
2017 Albert BB, Derraik JGB, Vickers MH, Garg ML, Cameron-Smith D, Hofman PL, Cutfield WS, 'Reply to ¿Letter to the editor: Determining the potential effects of oxidized fish oils in pregnant women requires a more systematic approach¿', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 312 (2017)
DOI 10.1152/ajpregu.00531.2016
2017 Albert BB, Derraik JGB, Garg ML, Cameron-Smith D, Cutfield WS, 'Concerns with the Study on Australian and New Zealand Fish Oil Products by Nichols et al. (Nutrients 2016, 8, 703)', NUTRIENTS, 9 (2017)
DOI 10.3390/nu9020137
Citations Scopus - 1Web of Science - 1
2017 Dias CB, Moughan PJ, Wood LG, Singh H, Garg ML, 'Postprandial lipemia: factoring in lipemic response for ranking foods for their healthiness.', Lipids Health Dis, 16 178 (2017)
DOI 10.1186/s12944-017-0568-5
Co-authors Lisa Wood
2017 Albert BB, Vickers MH, Gray C, Reynolds CM, Segovia SA, Derraik JGB, et al., 'Fish oil supplementation to rats fed high-fat diet during pregnancy prevents development of impaired insulin sensitivity in male adult offspring', Scientific Reports, 7 (2017)

© 2017 The Author(s). We examined whether maternal fish oil supplementation during pregnancy could prevent development of insulin resistance in adult male offspring of rat dams f... [more]

© 2017 The Author(s). We examined whether maternal fish oil supplementation during pregnancy could prevent development of insulin resistance in adult male offspring of rat dams fed a high-fat diet. Time-mated Sprague-Dawley rat dams were randomised into four treatment groups: Con-Con, dams fed a control diet (fat: 15% kcal) and administered water by gavage; Con-FO, control diet with unoxidised fish oil by gavage; HF-Con, high-fat diet (fat: 45% kcal) and water by gavage; and HF-FO, high-fat diet and unoxidised fish oil by gavage. Dams were fed the allocated diet ad libitum during pregnancy and lactation, but daily gavage occurred only during pregnancy. After weaning, male offspring consumed a chow diet ad libitum until adulthood. Maternal high-fat diet led to increased food consumption, adiposity, systolic blood pressure, and triglycerides and plasma leptin in adult HF-Con offspring. HF-Con offspring also exhibited lower insulin sensitivity than Con-Con rats. Male offspring from HF-FO group were similar to HF-Con regarding food consumption and most metabolic parameters. However, insulin sensitivity in the HF-FO group was improved relative to the HF-Con offspring. Supplementation with unoxidised n-3 PUFA rich oils in the setting of a maternal obesogenic diet improved insulin sensitivity, but had no impact on body composition of adult male offspring.

DOI 10.1038/s41598-017-05793-0
2017 Davis C, Hodgson J, Bryan J, Garg M, Woodman R, Murphy K, 'Older Australians Can Achieve High Adherence to the Mediterranean Diet during a 6 Month Randomised Intervention; Results from the Medley Study.', Nutrients, 9 (2017)
DOI 10.3390/nu9060534
2017 Nealon RS, Howe PRC, Jansen L, Garg M, Wong RHX, 'Impaired cerebrovascular responsiveness and cognitive performance in adults with type 2 diabetes', Journal of Diabetes and its Complications, 31 462-467 (2017)

© 2016 Elsevier Inc. Aim Cognitive deficits in type 2 diabetes mellitus (T2DM) may be partly attributable to stiffness in cerebral arteries and impaired vasodilator function, lim... [more]

© 2016 Elsevier Inc. Aim Cognitive deficits in type 2 diabetes mellitus (T2DM) may be partly attributable to stiffness in cerebral arteries and impaired vasodilator function, limiting the ability to increase blood flow in brain regions to meet cognitive demands. We undertook a comparison of cerebrovascular responsiveness (CVR) and cognitive performance in adults with and without T2DM. Methods Older adults with (50) and without (Herath, Cherbuin, Eramudugolla, & Anstey, 2016) T2DM underwent transcranial Doppler ultrasound measurements of basal cerebral mean blood flow velocity (MBFV) and pulsatility index (PI), a measure of arterial stiffness, in the middle cerebral arteries (MCA). A battery of tasks assessing domains of working memory, executive function and information processing/motor speed was then administered while MBFV was recorded. CVR to cognitive tasks was calculated as a percentage increase in MBFV from the basal level. Results There was no difference in basal MBFV between groups. However, PI was 14% higher in the T2DM group (P¿ < ¿0.05), who performed poorer across all cognitive domains assessed and displayed poorer CVR in three tasks. Cognitive performance was inversely related to the PI/MBFV ratio, an indicator of intracranial stenosis. Discussion Impaired cerebral perfusion during mental tasks is accompanied by poor cognitive performance and stiffness in the cerebral vessels.

DOI 10.1016/j.jdiacomp.2016.06.025
Citations Scopus - 1Web of Science - 3
Co-authors Rachel Wong, Peter Howe
2017 Goozee K, Chatterjee P, James I, Shen K, Sohrabi HR, Asih PR, et al., 'Elevated plasma ferritin in elderly individuals with high neocortical amyloid-ß load.', Mol Psychiatry, (2017)
DOI 10.1038/mp.2017.146
2017 Dias CB, Amigo N, Wood LG, Correig X, Garg ML, 'Effect of diets rich in either saturated fat or n-6 polyunsaturated fatty acids and supplemented with long-chain n-3 polyunsaturated fatty acids on plasma lipoprotein profiles.', Eur J Clin Nutr, (2017)
DOI 10.1038/ejcn.2017.56
Co-authors Lisa Wood
2017 Burrows TL, Rollo ME, Williams R, Wood LG, Garg ML, Jensen M, Collins CE, 'A Systematic Review of Technology-Based Dietary Intake Assessment Validation Studies That Include Carotenoid Biomarkers', NUTRIENTS, 9 (2017) [C1]
DOI 10.3390/nu9020140
Co-authors Lisa Wood, Megan Rollo, Clare Collins, Megan Jensen, Tracy Burrows
2016 Albert BB, Derraik JGB, Garg ML, Cameron-Smith D, Hofman PL, Cutfield WS, 'Challenging the claim that intake of krill oil is associated with increased metabolic risk in overweight men Reply', AMERICAN JOURNAL OF CLINICAL NUTRITION, 103 1558-1559 (2016)
DOI 10.3945/ajcn.116.133785
2016 Thota RN, Acharya SH, Abbott KA, Garg ML, 'Curcumin and long-chain Omega-3 polyunsaturated fatty acids for Prevention of type 2 Diabetes (COP-D): study protocol for a randomised controlled trial', TRIALS, 17 (2016)
DOI 10.1186/s13063-016-1702-9
Citations Scopus - 1Web of Science - 1
2016 Scott HA, Gibson PG, Garg ML, Upham JW, Wood LG, 'Sex hormones and systemic inflammation are modulators of the obese-asthma phenotype', Allergy: European Journal of Allergy and Clinical Immunology, 71 1037-1047 (2016) [C1]

© 2016 John Wiley &amp; Sons A/S. Published by John Wiley &amp; Sons Ltd. Background Both systemic inflammation and sex hormones have been proposed as potential mediators of ... [more]

© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. Background Both systemic inflammation and sex hormones have been proposed as potential mediators of the obese-asthma phenotype. The aim of this study was to examine the associations between sex hormones, oral contraceptive pill (OCP) use, systemic inflammation and airway inflammation in adults with asthma. Methods Obese (n = 39) and nonobese (n = 42) females and obese (n = 24) and nonobese (n = 25) males with asthma were recruited. Females were further categorized as reproductive-aged ( < 50 years old; n = 36) or older ( > 50 years old; n = 45). Thirteen (36.1%) reproductive-aged females were using the OCP. Participants had induced sputum cell counts measured and blood analysed for sex hormones and inflammatory markers. Results Obese reproductive-aged females had higher sputum %neutrophils than nonobese reproductive-aged females (45.4 ± 24.3% vs 27.5 ± 17.5%, P = 0.016); however, there was no difference in sputum neutrophils in obese compared with nonobese males (P = 0.620) or older females (P = 0.087). Multiple linear regression analysis found testosterone and OCP use to be negative predictors of sputum %neutrophils, while C-reactive protein and IL-6 were positive predictors of sputum %neutrophils. BMI and age were not significant predictors in the multivariate model. Reproductive-aged females using the OCP had significantly lower sputum %neutrophils than those not using the OCP (23.2 ± 12.6% vs 42.1 ± 23.8%, P = 0.015). Conclusions This study suggests that sex hormones and systemic inflammation may be mediating the obese-asthma phenotype. The observation that OCP use was associated with lower sputum %neutrophils in reproductive-aged females warrants further investigation.

DOI 10.1111/all.12891
Citations Scopus - 8Web of Science - 8
Co-authors Hayley Scott, Peter Gibson, Lisa Wood
2016 Phang M, Thorne RF, Alkhatatbeh MJ, Garg ML, Lincz LF, 'Circulating CD36+microparticles are not altered by docosahexaenoic or eicosapentaenoic acid supplementation', NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 26 254-260 (2016) [C1]
DOI 10.1016/j.numecd.2015.12.003
Co-authors Rick Thorne, Lisa Lincz
2016 Albert BB, Cameron-Smith D, Garg ML, Derraik JGB, Hofman PL, Cutfield WS, 'Marine oils: Complex, confusing, confounded?', Journal of Nutrition and Intermediary Metabolism, 5 3-10 (2016) [C1]

© 2016 Marine oils gained prominence following the report that Greenland Inuits who consumed a high-fat diet rich in long-chain n-3 polyunsaturated fatty acids (PUFAs) also had l... [more]

© 2016 Marine oils gained prominence following the report that Greenland Inuits who consumed a high-fat diet rich in long-chain n-3 polyunsaturated fatty acids (PUFAs) also had low rates of cardiovascular disease. Marine n-3 PUFAs have since become a billion dollar industry, which will continue to grow based on current trends. However, recent systematic reviews question the health benefits of marine oil supplements, particularly in the prevention of cardiovascular disease. Marine oils constitute an extremely complex dietary intervention for a number of reasons: i) the many chemical compounds they contain; ii) the many biological processes affected by n-3 PUFAs; iii) their tendency to deteriorate and form potentially toxic primary and secondary oxidation products; and iv) inaccuracy in the labelling of consumer products. These complexities may confound the clinical literature, limiting the ability to make substantive conclusions for some key health outcomes. Thus, there is a pressing need for clinical trials using marine oils whose composition has been independently verified and demonstrated to be minimally oxidised. Without such data, it is premature to conclude that n-3 PUFA rich supplements are ineffective.

DOI 10.1016/j.jnim.2016.03.003
Citations Scopus - 1
2016 Ferguson JJA, Stojanovski E, MacDonald-Wicks L, Garg ML, 'Fat type in phytosterol products influence their cholesterol-lowering potential: A systematic review and meta-analysis of RCTs', Progress in Lipid Research, 64 16-29 (2016) [C1]

© 2016 Elsevier B.V. The most common form of phytosterol (PS) fortified foods are fat spreads and dairy products. The predominant fats used are soybean/sunflower (SS) or rapeseed... [more]

© 2016 Elsevier B.V. The most common form of phytosterol (PS) fortified foods are fat spreads and dairy products. The predominant fats used are soybean/sunflower (SS) or rapeseed/canola (RC) oils and animal fat (D) in dairy products. This review aimed to investigate whether the carrier fat is a determinant of the hypocholesterolaemic effects of PS fortified foods. Databases were searched using relevant keywords and published RCTs from 1990 investigating the effects of dietary PS intervention (=¿1.5¿g per day) on total cholesterol and LDL-C were included. After methodological quality assessment and data extraction, a total of 32 RCTs (RC, n¿=¿15; SS, n¿=¿9; D, n¿=¿8) were included. As expected, all fat groups significantly reduced TC and LDL-C (p¿ < ¿0.01). When compared across different carrier fats, RC as the main carrier fat, reduced LDL-C significantly more than the SS spreads (p¿=¿0.01). Therefore, a combination of monounsaturated fatty acid rich spread with adequate amounts of omega-3 fatty acids (as evident in RC spreads) may be the superior carrier fat for the delivery of PS for optimal blood cholesterol-lowering. The findings of this research provide useful evidence for optimising the hypocholesterolaemic effects of PS and support further investigation into the possible mechanisms behind these findings.

DOI 10.1016/j.plipres.2016.08.002
Citations Scopus - 4Web of Science - 5
Co-authors Elizabeth Stojanovski, Lesley Wicks
2016 Abbott KA, Veysey M, Lucock M, Niblett S, King K, Burrows T, Garg ML, 'Sex-dependent association between erythrocyte n-3 PUFA and type 2 diabetes in older overweight people.', Br J Nutr, 115 1379-1386 (2016) [C1]
DOI 10.1017/S0007114516000258
Citations Scopus - 1Web of Science - 1
Co-authors Martin Veysey, Mark Lucock, Tracy Burrows, Katrina King
2016 Albert BB, Vickers MH, Gray C, Reynolds CM, Segovia SA, Derraik JGB, et al., 'Oxidized fish oil in rat pregnancy causes high newborn mortality and increases maternal insulin resistance.', Am J Physiol Regul Integr Comp Physiol, 311 R497-R504 (2016) [C1]
DOI 10.1152/ajpregu.00005.2016
Citations Scopus - 5Web of Science - 5
2016 Dias CB, Wood LG, Garg ML, 'Effects of dietary saturated and n-6 polyunsaturated fatty acids on the incorporation of long-chain n-3 polyunsaturated fatty acids into blood lipids', European Journal of Clinical Nutrition, 70 812-818 (2016) [C1]

© 2016 Macmillan Publishers Limited. Background/Objectives: Omega-3 polyunsaturated fatty acids (n-3PUFA) are better absorbed when they are combined with high-fat meals. However,... [more]

© 2016 Macmillan Publishers Limited. Background/Objectives: Omega-3 polyunsaturated fatty acids (n-3PUFA) are better absorbed when they are combined with high-fat meals. However, the role of different dietary fats in modulating the incorporation of n-3PUFA in blood lipids in humans has not been previously explored. Omega-6 polyunsaturated fatty acids (n-6PUFA) are known to compete with n-3PUFA in the metabolic pathways and for the incorporation into phospholipids, whereas saturated fats (SFA) may enhance n-3PUFA incorporation into tissues. Subjects/Methods: In a randomized parallel-design trial, we aimed to investigate the long-term effects of n-3PUFA supplementation in subjects consuming a diet enriched with either SFA or n-6PUFA on fatty acid incorporation into plasma and erythrocytes and on blood lipid profiles (total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides). Results: Dietary supplementation with n-3PUFA co-administered with SFA for 6 weeks resulted in a significant rise in total cholesterol (0.46±0.60 mmol/L; P=0.020) and LDL-C (0.48±0.48 mmol/L; P=0.011) in comparison with combination with n-6PUFA. The diet enriched with SFA also induced a greater increase in eicosapentaenoic acid (2.07±0.79 vs 1.15±0.53; P=0.004), a smaller decrease in docosapentaenoic acid (-0.12±0.23 vs -0.30±0.20; P=0.034) and a similar increase in docosahexaenoic acid (3.85±1.14 vs 3.10±1.07; P=0.128) percentage in plasma compared with the diet enriched with n-6PUFA. A similar effect was seen in erythrocytes. N-3PUFA supplementation resulted in similar changes in HDL-C and triglyceride levels. Conclusions: The results suggest that dietary substitution of SFA with n-6PUFA, despite maintaining low levels of circulating cholesterol, hinders n-3PUFA incorporation into plasma and tissue lipids.

DOI 10.1038/ejcn.2015.213
Citations Scopus - 4Web of Science - 3
Co-authors Lisa Wood
2016 Mingay E, Veysey M, Lucock M, Niblett S, King K, Patterson A, Garg M, 'Sex-dependent association between omega-3 index and body weight status in older Australians', Journal of Nutrition and Intermediary Metabolism, 5 70-77 (2016) [C1]

© 2016 The Authors Background/objectives Restricting energy intake for weight management in older adults has potential to adversely affect nutritional status and result in impair... [more]

© 2016 The Authors Background/objectives Restricting energy intake for weight management in older adults has potential to adversely affect nutritional status and result in impairment of an already compromised immune system. Investigation of alternative strategies to combat adiposity and sustain lean muscle mass in older adults are warranted to minimise the risk of developing chronic diseases. Long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), may play an important role through their impact on increased fat oxidation and reduced inflammation. This study aimed to examine the association between erythrocyte membrane LCn-3PUFA and anthropometric measures in an older population. Subjects/methods A cross-sectional sample of older adults (n¿=¿620; age 65¿95 years; 56.3% females) from the Retirement Health and Lifestyle Study (RHLS) was analysed. Anthropometric measurements, including height, weight, body mass index (BMI), waist (WC) and hip circumference (HC) were taken. The fatty acid composition of erythrocyte membranes was analysed via gas chromatography (GC) to determine the omega-3 index (%EPA plus %DHA). Results An inverse association was detected between the omega-3 index and anthropometric measures, BMI (r¿=¿-0.076, p=0.06), WC (r¿=¿-0.118, p¿ < ¿0.01) and waist-to-hip ratio (WHR; r¿=¿-0.149, p¿ < ¿0.001). Stratification of data by sex (females, n¿=¿349; males, n¿=¿271) indicated that these associations were sex-specific. Females displayed an inverse association between the omega-3 index and BMI (r¿=¿-0.146, p¿ < ¿0.01) and WC (r¿=¿-0.125, p¿ < ¿0.05). In contrast, no significant association between the omega-3 index and anthropometric measures was detected in males. After correcting for the potentially confounding effects of age, household income, fish oil supplement status, daily dietary energy intake and total physical activity times, the omega-3 index was inversely associated with BMI and WC in females but not males. Conclusions Omega-3 status was associated with weight status, particularly in older women but not in men. These results suggest the need for sex-based intervention trials to examine the role of dietary intake and/or supplementation of LCn-3PUFA in weight management of older adults.

DOI 10.1016/j.jnim.2016.04.001
Co-authors Katrina King, Mark Lucock, Amanda Patterson, Martin Veysey
2016 Rose M, Veysey M, Lucock M, Niblett S, King K, Baines S, Garg ML, 'Association between erythrocyte omega-3 polyunsaturated fatty acid levels and fatty liver index in older people is sex dependent', Journal of Nutrition and Intermediary Metabolism, 5 78-85 (2016) [C1]

© 2016 The Authors Background/Objectives Non-alcoholic fatty liver disease (NAFLD) is highly prevalent in older people but currently no specific drugs are available for its treat... [more]

© 2016 The Authors Background/Objectives Non-alcoholic fatty liver disease (NAFLD) is highly prevalent in older people but currently no specific drugs are available for its treatment. Omega-3 polyunsaturated fatty acids (n-3PUFA), known for their lipid-lowering, anti-inflammatory and anti-hypertensive properties, may have therapeutic potential for the management of NAFLD. The aim of this study was to determine whether n-3PUFA levels are associated with the prevalence of NAFLD in older adults. Methods A cross-sectional sample of older adults aged 65¿95 years (n¿=¿620) from the Retirement Health and Lifestyle Study (RHLS) was analysed. Fatty Liver Index (FLI) scores, used as an indicator of NAFLD risk, were calculated using a validated a lgorithm that incorporates body mass index, waist circumference, plasma triglycerides and ¿-glutamyl transferase. Omega-3 index scores (O3I, %eicosapentaenoic acid plus %docosahexaenoic acid) were determined by analysing the fatty acid composition of erythrocyte membranes by gas chromatography. Results Following application of exclusion criteria, 475 participants were included in the analysis (age 77.9¿±¿7.0 years; 60.4% females). Of these, 216 participants had FLI scores (=60) suggestive of NAFLD (age 77.0¿±¿6.6 years; 49.1% females). O3I was significantly lower in participants with NAFLD compared to those without NAFLD (p¿ < ¿0.01). A significant inverse relationship was found between O3I and FLI (r¿=¿-0.165; p¿ < ¿0.001). This relationship was gender specific with women, but not men, showing a significant association (r¿=¿-0.206; p¿ < ¿0.001). Conclusions The current study demonstrated a sex-dependent inverse relationship between erythrocyte n-3PUFA concentrations and NAFLD in older adults. The finding supports the proposal for sex-stratified n-3PUFA intervention trials in this high-risk age group.

DOI 10.1016/j.jnim.2016.04.007
Co-authors Martin Veysey, Mark Lucock, Surinder Baines, Katrina King
2016 Olliver M, Veysey M, Lucock M, Niblett S, King K, MacDonald-Wicks L, Garg ML, 'Erythrocyte omega-3 polyunsaturated fatty acid levels are associated with biomarkers of inflammation in older Australians', Journal of Nutrition and Intermediary Metabolism, 5 61-69 (2016) [C1]

© 2016 The Authors Background Elevated levels of pro-inflammatory mediators heighten the risk of developing or aggravating a spectrum of chronic diseases and are a strong predict... [more]

© 2016 The Authors Background Elevated levels of pro-inflammatory mediators heighten the risk of developing or aggravating a spectrum of chronic diseases and are a strong predictor of mortality in elderly cohorts. Omega-3 polyunsaturated fatty acids (n-3PUFA), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are known to possess anti-inflammatory properties. However, the relationship between erythrocyte membrane n-3PUFA and inflammation biomarkers has not been well established. Objective This study aimed to determine if n-3PUFA status, together with the omega-3 index (O3I, erythrocyte membrane % EPA plus DHA), is associated with pro-inflammatory mediators in older Australians. Methods The study was a cross-sectional analysis of randomly selected older men and women aged =65 years (n¿=¿620) recruited from the Central Coast of NSW, Australia. Fasted blood samples were analysed for C-reactive protein (CRP), fibrinogen and full blood count using standardised laboratory methods. The fatty acid composition of erythrocyte membranes was analysed via gas chromatography to determine n-3PUFA levels. The relationships between n-3PUFA and inflammatory mediators were evaluated in multivariate regression models after adjusting for known inflammatory confounders. Results After excluding participants who had an inflammatory disease, CRP levels > 10¿mg/L, or who were taking anti-inflammatory medications or n-3PUFA supplements, 126 participants (age 77.6¿±¿7.3 years; females, 46%) were included in the analysis. After multivariate adjustments, O3I was inversely associated with CRP (ß¿=¿-0.209, p¿ < ¿0.05) and monocyte cell counts (ß¿=¿-0.205, p¿ < ¿0.05), and total n-3PUFA was inversely related to WBC (ß¿=¿-0.238, p¿ < ¿0.05), neutrophils (ß¿=¿-0.212, p¿ < ¿0.05) and monocytes (ß¿=¿-0.246, p¿ < ¿0.05). However no association between fibrinogen and O3I or total n-3PUFA was detected. Conclusions This study demonstrated a negative association between O3I and biomarkers of inflammation in an older population. The findings support a potential role for n-3PUFA supplementation in the management of inflammatory diseases.

DOI 10.1016/j.jnim.2016.03.002
Co-authors Lesley Wicks, Mark Lucock, Martin Veysey, Katrina King
2016 Ferguson JJA, Veysey M, Lucock M, Niblett S, King K, MacDonald-Wicks L, Garg ML, 'Association between omega-3 index and blood lipids in older Australians', Journal of Nutritional Biochemistry, 27 233-240 (2016) [C1]

© 2015 Elsevier Inc. Management of hyperlipidaemia remains a cornerstone therapy for the prevention of cardiovascular disease (CVD). Dietary supplementation with n-3 polyunsatura... [more]

© 2015 Elsevier Inc. Management of hyperlipidaemia remains a cornerstone therapy for the prevention of cardiovascular disease (CVD). Dietary supplementation with n-3 polyunsaturated fatty acid (PUFA) has been shown to modulate blood lipid profiles and reduce the risk of developing CVD. However, studies relating objective measures of long-term dietary n-3 PUFA intake and circulating lipid levels in older adults are limited. Thus, we aimed to determine whether there is an association between erythrocyte n-3 PUFA status (omega-3 index, O3I) and blood lipid profiles in older adults. A sample of adults aged 65-95 years who participated in the Retirement Health and Lifestyle Study was evaluated. Outcome measures included O3I (% eicosapentaenoic acid+% docosahexaenoic acid) and fasting blood lipid profiles [total cholesterol (TC), low-density lipoprotein (LDL)-cholesterol, high-density lipoprotein (HDL)-cholesterol and triglyceride (TG)]. Two hundred and seventy-six subjects were included in the analyses. The mean±SD age was 77.6±7.4 years, and 40.9% were males. O3I was significantly higher in females compared to males. O3I was inversely associated with plasma TG (P < .001) and TC/HDL-cholesterol ratio (P < .05), and positively associated with HDL-cholesterol (P < .05), in all subjects. Associations between O3I and TG were evident in both females (r=-0.250, P < .01) and males (r=-0.225, P < .05). In females only, the odds of being hypertriglyceridaemic were highest in those with lowest O3I (P=006). Trends for hypercholesterolaemia and elevated LDL risk were converse between males and females. Long-term n-3 PUFA status is associated with blood lipid profiles in older Australians. Our findings support the development and implementation of age-specific dietary strategies to reduce the risk of CVD via improving the O3I.

DOI 10.1016/j.jnutbio.2015.09.010
Citations Scopus - 3Web of Science - 1
Co-authors Lesley Wicks, Martin Veysey, Mark Lucock, Katrina King
2016 Abbott KA, Burrows TL, Thota RN, Acharya S, Garg ML, 'Do v-3 PUFAs affect insulin resistance in a sex-specific manner? A systematic review and meta-analysis of randomized controlled trials', American Journal of Clinical Nutrition, 104 1470-1484 (2016) [C1]

© 2016 American Society for Nutrition. Background: Evidence has suggested that omega-3 (n-3) polyunsaturated fatty acids (PUFAs) improve obesity-induced insulin resistance (IR); ... [more]

© 2016 American Society for Nutrition. Background: Evidence has suggested that omega-3 (n-3) polyunsaturated fatty acids (PUFAs) improve obesity-induced insulin resistance (IR); however, results from human intervention trials have been equivocal. Recently it has been reported that n-3 PUFA status is inversely associated with type 2 diabetes in women but not in men, suggesting a sex-dependent effect. Objective: We aimed to determine whether n-3 PUFA interventions affect IR in a sex-dependent manner. Design: Five databases were searched (Medline, EMBASE, CINAHL, Scopus, and Pre-Medline) for randomized controlled trials. Searches were limited to the English language and to studies with adults aged .18 y. When possible, studies were pooled for a meta-analysis. The principle summary measure was the standardized mean difference (SMD) between groups. Results: Thirty-one eligible trials were identified with a total of 1848 participants [men: 45.1%; weighted mean 6 SD age: 52.5 6 8.2 y; weighted body mass index (in kg/m2): 28.8 6 3.0]. Seven studies were conducted in women, 4 studies were conducted in men, and the remaining studies pooled men and women together. Twenty-six trials were pooled for the meta-analysis (men: n = 2; women: n = 6). With all studies (n = 26) pooled, there was no effect of n-3 PUFA on IR at the group level (SMD: 0.089; 95% CI: 20.105, 0.283; P = 0.367). In trials of 6 wk, a significant improvement in IR was seen in women (SMD: 20.266; 95% CI: 20.524, 20.007; P = 0.045) but not in men (SMD: 0.619; 95% CI: 20.583, 1.820; P = 0.313). Conclusions: With this analysis, we provide preliminary evidence of a sex-dependent response of IR to an n-3 PUFA intervention. Additional studies are needed to confirm sex-dependent associations and to elucidate the potential mechanisms that are involved.

DOI 10.3945/ajcn.116.138172
Citations Scopus - 1Web of Science - 1
Co-authors Tracy Burrows
2015 Dias CB, Phang M, Wood LG, Garg ML, 'Postprandial Lipid Responses do not Differ Following Consumption of Butter or Vegetable Oil when Consumed with Omega-3 Polyunsaturated Fatty Acids', Lipids, (2015) [C1]

Dietary saturated fat (SFA) intake has been associated with elevated blood lipid levels and increased risk for the development of chronic diseases. However, some animal studies ha... [more]

Dietary saturated fat (SFA) intake has been associated with elevated blood lipid levels and increased risk for the development of chronic diseases. However, some animal studies have demonstrated that dietary SFA may not raise blood lipid levels when the diet is sufficient in omega-3 polyunsaturated fatty acids (n-3PUFA). Therefore, in a randomised cross-over design, we investigated the postprandial effects of feeding meals rich in either SFA (butter) or vegetable oil rich in omega-6 polyunsaturated fatty acids (n-6PUFA), in conjunction with n-3PUFA, on blood lipid profiles [total cholesterol, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and triacylglycerol (TAG)] and n-3PUFA incorporation into plasma lipids over a 6-h period. The incremental area under the curve for plasma cholesterol, LDL-C, HDL-C, TAG and n-3PUFA levels over 6 h was similar in the n-6PUFA compared to SFA group. The postprandial lipemic response to saturated fat is comparable to that of n-6PUFA when consumed with n-3PUFA; however, sex-differences in response to dietary fat type are worthy of further attention.

DOI 10.1007/s11745-015-4003-2
Citations Scopus - 2Web of Science - 1
Co-authors Lisa Wood
2015 Jameel F, Thota RN, Wood LG, Plunkett B, Garg ML, 'Sex-dependent association between circulating irisin levels and insulin resistance in healthy adults', Journal of Nutrition and Intermediary Metabolism, 2 86-92 (2015) [C1]

© 2015 The Authors. Published by Elsevier Inc. Background Irisin, a myokine, expressed by muscle and adipose tissue, has been reported to stimulate conversion of white into brown... [more]

© 2015 The Authors. Published by Elsevier Inc. Background Irisin, a myokine, expressed by muscle and adipose tissue, has been reported to stimulate conversion of white into brown adipose tissue. The beneficial health effects of exercise are thought to be mediated in part, via increased production of irisin. Objective The primary aim of this study was to assess the association between plasma irisin levels glycaemic indices in healthy adults. Associations between irisin and lipid levels, CRP and body composition were explored as secondary outcomes. Methods A cross-sectional sample of forty nine (n = 49) free living healthy males (n = 28) and females (n = 21), between the ages of 18 and 65, with body mass index (BMI) within the healthy range, were recruited. Body weight, height, and body composition measurements were taken. Fasting blood samples were collected for the analysis of glucose, insulin and irisin levels. Insulin resistance score, HOMA-IR, was calculated using fasting blood glucose and insulin values. The relationship between plasma irisin levels and anthropometric measurements, glucose, insulin and HOMA-IR was determined using Spearman's bivariate correlation test. Results A significant inverse relationship was found between plasma irisin levels and insulin(r = -0.380; P = 0.007) and HOMA-IR(r = -0.362; P = 0.011). This relation was further strengthened in males when the data was stratified by gender. Circulating irisin levels were positively correlated with HDL-C (r = 0.39; P = 0.05) in male participants. Additionally, there was a significant negative correlation between percent body fat (r = -0.43, P < 0.05) and body fat mass (r = -0.47, P < 0.05) and circulating irisin levels in male participants. Conclusions This study reports a sex-dependent inverse relationship between plasma irisin levels and insulin resistance in healthy subjects.

DOI 10.1016/j.jnim.2015.10.001
Citations Scopus - 1
Co-authors Lisa Wood
2015 Petersen KS, Keogh JB, Meikle PJ, Garg ML, Clifton PM, 'Dietary predictors of arterial stiffness in a cohort with type 1 and type 2 diabetes', Atherosclerosis, 238 175-181 (2015) [C1]

© 2014. Objective: To determine the dietary predictors of central blood pressure, augmentation index and pulse wave velocity (PWV) in subjects with type 1 and type 2 diabetes. Me... [more]

© 2014. Objective: To determine the dietary predictors of central blood pressure, augmentation index and pulse wave velocity (PWV) in subjects with type 1 and type 2 diabetes. Methods: Participants were diagnosed with type 1 or type 2 diabetes and had PWV and/or pulse wave analysis performed. Dietary intake was measured using the Dietary Questionnaire for Epidemiological Studies Version 2 Food Frequency Questionnaire. Serum lipid species and carotenoids were measured, using liquid chromatography electrospray ionization-tandem mass spectrometry and high performance liquid chromatography, as biomarkers of dairy and vegetable intake, respectively. Associations were determined using linear regression adjusted for potential confounders. Results: PWV ( n=95) was inversely associated with reduced fat dairy intake ( ß=-0.01; 95% CI-0.02,-0.01; p=0 < 0.05) in particular yoghurt consumption ( ß=-0.04; 95% CI-0.09,-0.01; p=0 < 0.05) after multivariate adjustment. Total vegetable consumption was negatively associated with PWV in the whole cohort after full adjustment ( ß=-0.04; 95% CI-0.07,-0.01; p < 0.05). Individual lipid species, particularly those containing 14:0, 15:0, 16:0, 17:0 and 17:1 fatty acids, known to be of ruminant origin, in lysophosphatidylcholine, cholesterol ester, diacylglycerol, phosphatidylcholine, sphingomyelin and triacylglycerol classes were positively associated with intake of full fat dairy, after adjustment for multiple comparisons. However, there was no association between serum lipid species and PWV. There were no dietary predictors of central blood pressure or augmentation index after multivariate adjustment. Conclusion: In this cohort of subjects with diabetes reduced fat dairy intake and vegetable consumption were inversely associated with PWV. The lack of a relationship between serum lipid species and PWV suggests that the fatty acid composition of dairy may not explain the beneficial effect.

DOI 10.1016/j.atherosclerosis.2014.12.012
Citations Scopus - 4Web of Science - 6
2015 Parker HM, O'Connor HT, Keating SE, Cohn JS, Garg ML, Caterson ID, et al., 'Efficacy of the Omega-3 Index in predicting non-alcoholic fatty liver disease in overweight and obese adults: A pilot study', British Journal of Nutrition, 114 780-787 (2015) [C1]

© 2015 The Authors. Non-alcoholic fatty liver disease (NAFLD) is an independent predictor of CVD in otherwise healthy individuals. Low n-3 PUFA intake has been associated with th... [more]

© 2015 The Authors. Non-alcoholic fatty liver disease (NAFLD) is an independent predictor of CVD in otherwise healthy individuals. Low n-3 PUFA intake has been associated with the presence of NAFLD; however, the relationship between a biomarker of n-3 status - the Omega-3 Index - and liver fat is yet to be elucidated. A total of eighty overweight adults (fifty-six men) completed the anthropometric and biochemical measurements, including the Omega-3 Index, and underwent proton magnetic resonance spectroscopy assessment of liver fat. Bivariate correlations and multiple regression analyses were performed with reference to prediction of liver fat percentage. The mean Omega-3 Index was high in both NAFLD (intrahepatic lipid concentration=5·5 %) and non-NAFLD groups. The Omega-3 Index, BMI, waist circumference, glucose, insulin, TAG, high-sensitive C-reactive protein (hsCRP) and alanine aminotransferase (ALT) were positively correlated, and HDL and erythrocyte n-6:n-3 ratio negatively correlated with liver fat concentration. Regression analysis found that simple anthropometric and demographic variables (waist, age) accounted for 31 % of the variance in liver fat and the addition of traditional cardiometabolic blood markers (TAG, HDL, hsCRP and ALT) increased the predictive power to 43 %. The addition of the novel erythrocyte fatty acid variable (Omega-3 Index) to the model only accounted for a further 3 % of the variance (P=0·049). In conclusion, the Omega-3 Index was associated with liver fat concentration but did not improve the overall capacity of demographic, anthropometric and blood markers to predict NAFLD.

DOI 10.1017/S0007114515002305
Citations Scopus - 2Web of Science - 1
2015 Albert BB, Derraik JGB, Cameron-Smith D, Hofman PL, Tumanov S, Villas-Boas SG, et al., 'Fish oil supplements in New Zealand are highly oxidised and do not meet label content of n-3 PUFA', SCIENTIFIC REPORTS, 5 (2015) [C1]
DOI 10.1038/srep07928
Citations Scopus - 47Web of Science - 37
2015 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Determinants of weight loss success utilizing a meal replacement plan and/or exercise, in overweight and obese adults with asthma', Respirology, 20 243-250 (2015) [C1]

© 2014 Asian Pacific Society of Respirology. Background and objective While weight loss has been shown to reduce obesity-related comorbidity, many weight loss treatments fail. Fa... [more]

© 2014 Asian Pacific Society of Respirology. Background and objective While weight loss has been shown to reduce obesity-related comorbidity, many weight loss treatments fail. Factors that enhance weight loss success are unknown, particularly in those with asthma. The aim of the study was to identify patient characteristics that predict weight loss success in adults with asthma. Methods Baseline and change in asthma characteristics and eating behaviours were investigated for relationships with weight loss and fat loss using multiple linear regression, in 38 overweight and obese adults with asthma randomized to dietary, exercise or combined interventions targeting weight loss for 10 weeks. Results Mean ± standard deviation weight loss was 6.6 ± 5.1 kg. Greater %weight loss and %fat loss was achieved in those with poorer asthma-related quality of life at baseline ((r s = 0.398, P = 0.015) and (r s = 0.455, P = 0.005) respectively), with 1.7% greater absolute weight loss at week 10 corresponding to each one unit reduction in the asthma-related quality of life score at baseline. Furthermore, a lower baseline forced expiratory volume in 1 s/forced vital capacity correlated with greater weight loss (r s = 0.398, P = 0.015). Male sex was associated with a 3.6 kg greater weight loss (P = 0.087). Reducing emotional eating during the programme was associated with greater weight loss in women (r s = 0.576, P = 0.010). Conclusions This study demonstrates that individuals with more severe asthma at baseline are more successful in achieving weight loss, which could be a consequence of greater motivation and could be used as a motivational tool within th e clinical setting. Gender tailoring of weight loss programmes may be useful to enhance weight loss success. Future studies are urgently needed to establish predictors of long-term weight loss maintenance in those with asthma. See Editorial, page 179 This study is the first to demonstrate that more severe asthma at baseline, male sex, and improvements in eating behaviours during weight loss are associated with greater weight loss success in overweight and obese adults with asthma. Our findings may inform the development of asthma-specific weight management guidelines.

DOI 10.1111/resp.12423
Citations Scopus - 3Web of Science - 3
Co-authors Hayley Scott, Philip Morgan, Robin Callister, Lisa Wood, Peter Gibson
2015 Burrows TL, Williams R, Rollo M, Wood L, Garg ML, Jensen M, Collins CE, 'Plasma carotenoid levels as biomarkers of dietary carotenoid consumption: A systematic review of the validation studies', Journal of Nutrition and Intermediary Metabolism, 2 15-64 (2015) [C1]

© 2015 The Authors. Published by Elsevier Ltd. Background Previous research has demonstrated that plasma carotenoids are a reliable biomarker of usual fruit and vegetable intake.... [more]

© 2015 The Authors. Published by Elsevier Ltd. Background Previous research has demonstrated that plasma carotenoids are a reliable biomarker of usual fruit and vegetable intake. The review aims were to synthesize (i) the mean dietary intake and (ii) plasma concentrations of carotenoids reported from validation studies (iii) compare the strength of the relationship between the two, measured using different dietary assessment methods. Methods Six databases were used to locate studies that included: adult populations, assessment of dietary intake, measurement of plasma carotenoids and reported the comparison between the two measures. Results One hundred and forty-two studies were included with 95,480 participants, the majority of studies were cross-sectional (n = 86), with randomized controlled trials (RCTs) (n = 18), 14 case-control studies and 13 cohorts. The most common reported dietary carotenoid and plasma carotenoid was lycopene: weighted dietary mean intake (4555.4 ug/day), and plasma concentration 0.62 umol/L (95% CI: 0.61, 0.63, n = 56studies. The strongest weighted correlation between the two measures was found for cryptoxanthin (r = 0.38, 95% CI 0.34, 0.42) followed by a-carotene (r = 0.34, 95% CI 0.31, 0.37). Conclusion This review summarizes typical dietary intakes and plasma concentrations and their expected associations based on validation studies conducted to date which provides a benchmark for future validation studies.

DOI 10.1016/j.jnim.2015.05.001
Citations Scopus - 6
Co-authors Megan Jensen, Megan Rollo, Lisa Wood, Clare Collins, Tracy Burrows
2015 Grant R, Bilgin A, Guest J, Morris MJ, Garg ML, Pearce R, 'The Relative Value of Measures of Omega-3 Index, Perceived Stress, Cortisol and Sleep Time in Identifying Depression Among a Cohort of Australian Adolescents', International Journal of Child Health and Nutrition, 4 40-49 (2015) [C1]
2015 Garg M, 'Editorial for the launch/inaugural issue of the Journal of Nutrition & Intermediary Metabolism', Journal of Nutrition & Intermediary Metabolism, 2 1-1 (2015) [C2]
DOI 10.1016/j.jnim.2015.08.001
2015 Albert BB, Derraik JGB, Brennan CM, Biggs JB, Garg ML, Cameron-Smith D, et al., 'Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men', AMERICAN JOURNAL OF CLINICAL NUTRITION, 102 49-57 (2015) [C1]
DOI 10.3945/ajcn.114.103028
Citations Scopus - 10Web of Science - 8
2015 Thomas J, Garg ML, Smith DW, 'Effects of dietary supplementation with docosahexaenoic acid (DHA) on hippocampal gene expression in streptozotocin induced diabetic C57Bl/6 mice', Journal of Nutrition and Intermediary Metabolism, 2 2-7 (2015) [C1]

© 2015 The Authors. A body of evidence has accumulated indicating diabetes is associated with cognitive impairments. Effective strategies are therefore needed that will delay or ... [more]

© 2015 The Authors. A body of evidence has accumulated indicating diabetes is associated with cognitive impairments. Effective strategies are therefore needed that will delay or prevent the onset of these diabetes-related deficits. In this regard, dietary modification with the naturally occurring compound, docosahexaenoic acid (DHA), holds significant promise as it has been shown to have anti-inflammatory, anti-oxidant, and anti-apoptotic properties. The hippocampus, a limbic structure involved in cognitive functions such as memory formation, is particularly vulnerable to the neurotoxic effects related to diabetes, and we have previously shown that streptozotocin-induced diabetes alters hippocampal gene expression, including genes involved in synaptic plasticity and neurogenesis. In the present study, we explored the effects of dietary supplementation with DHA on hippocampal gene expression in C57Bl/6 diabetic mice. Diabetes was established using streptozotocin (STZ) and once stable, the dietary intervention group received AIN93G diet supplemented with DHA (50 mg/kg/day) for 6 weeks. Microarray based genome-wide expression analysis was carried out on the hippocampus of DHA supplemented diabetic mice and confirmed by real time polymerase chain reaction (RT-qPCR). Genome-wide analysis identified 353 differentially expressed genes compared to non-supplemented diabetic mice. For example, six weeks of dietary DHA supplementation resulted in increased hippocampal expression of Igf II and Sirt1 and decreased expression of Tnf-a, Il6, Mapkapk2 and ApoE, compared to non-supplemented diabetic mice. Overall, DHA supplementation appears to alter hippocampal gene expression in a way that is consistent with it being neuroprotective in the context of the metabolic and inflammatory insults associated with diabetes.

DOI 10.1016/j.jnim.2015.04.001
Co-authors Douglas Smith
2015 Dias CB, Wood LG, Phang M, Garg ML, 'Kinetics of omega-3 polyunsaturated fatty acids when co-administered with saturated or omega-6 fats', Metabolism: Clinical and Experimental, (2015) [C1]

Objective: Absorption of long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) has been shown to be potentiated when consumed with a high fat meal. However, the effect of dif... [more]

Objective: Absorption of long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) has been shown to be potentiated when consumed with a high fat meal. However, the effect of different dietary fats on n-3PUFA absorption and postprandial kinetics has not been previously studied. Method: In a randomized cross-over design intervention, postprandial incorporation of LCn-3PUFA into plasma lipids following consumption of a meal rich in either saturated fat or omega-6 polyunsaturated fatty acids (n-6PUFA) was investigated. Healthy adult male and female subjects (n = 26) were fed an isocaloric meal containing equivalent amount of either butter or sunflower seed oil supplemented with 1.8. grams of LCn-3PUFA (300. mg eicosapentaenoic acid, 20:5n-3 and 1500. mg docosahexaenoic acid, 22:6n-3). Results: Postprandial plasma lipids were enriched with saturated fatty acids and linoleic acid (18:2n-6) following consumption of the butter and the sunflower oil containing meals respectively. The increase in plasma 20:5n-3 and 22:6n-3 levels over the 6. hour study period was similar in both the saturated and the n-6 fat groups. Conclusion: These results suggest that the expected competition between LCn-3PUFA and n-6PUFA at the absorption level is unlikely; therefore competition at the enzymatic level should be primarily responsible for differences in their metabolic and clinical effects.Trial registered with the Australia New Zealand Trial registry as ACTRN12612000654853.

DOI 10.1016/j.metabol.2015.08.012
Citations Scopus - 2Web of Science - 2
Co-authors Lisa Wood
2014 Wong R, Garg M, Wood L, Howe P, 'Antihypertensive Potential of Combined Extracts of Olive Leaf, Green Coffee Bean and Beetroot: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial', Nutrients, 6 4881-4894 (2014) [C1]
DOI 10.3390/nu6114881
Citations Scopus - 3Web of Science - 3
Co-authors Peter Howe, Lisa Wood, Rachel Wong
2014 Alhazmi A, Stojanovski E, Garg ML, McEvoy M, 'Fasting whole blood fatty acid profile and risk of type 2 diabetes in adults: a nested case control study.', PLoS One, 9 e97001 (2014) [C1]
DOI 10.1371/journal.pone.0097001
Citations Scopus - 9Web of Science - 8
Co-authors Elizabeth Stojanovski, Mark Mcevoy
2014 Dias CB, Garg R, Wood LG, Garg ML, 'Saturated fat consumption may not be the main cause of increased blood lipid levels', Medical Hypotheses, 82 187-195 (2014) [C1]

Consumption of foods rich in saturated fatty acids (SFA) has often been associated with elevated blood lipid levels and consequently with risk for chronic diseases, including coro... [more]

Consumption of foods rich in saturated fatty acids (SFA) has often been associated with elevated blood lipid levels and consequently with risk for chronic diseases, including coronary heart disease. However, epidemiological and interventional studies on this topic are contradictory. While some studies have established a positive link, other studies have failed to show a significant association between saturated fat consumption and blood lipid levels, and others have even found an inverse association. Moreover, studies using animal models have demonstrated that dietary saturated fats raise blood lipid (cholesterol and triglycerides) levels only when the diet is deficient in omega-3 polyunsaturated fatty acids (n-3PUFA). The n-3PUFA are known for their potential in the management of hyperlipidaemia for the prevention of coronary heart disease, as well as for their anti-arrhythmic, anti-aggregatory and anti-inflammatory potential. We believe that with an adequate consumption of n-3PUFA dietary saturated fat may not result in elevated blood lipid levels. Therefore, we critically evaluated the literature regarding saturated fat and blood lipid level, with an emphasis on the role of n-3PUFA on this relationship. Evidence from animal studies and few clinical trials lead to the hypothesis that there are beneficial or neutral effects of saturated fatty acids when combined with recommended levels of n-3PUFA in the diet. However, an intervention focusing on the background fat when the volunteers' diet is supplemented with n-3PUFA is yet to be done. Proving the authenticity of this hypothesis would mean a substantial change in public health messages regarding saturated fats and their health effects; and also a change in the strategies related to prevention of chronic cardiac and artery diseases. © 2013 Elsevier Ltd.

DOI 10.1016/j.mehy.2013.11.036
Citations Scopus - 8Web of Science - 6
Co-authors Lisa Wood
2014 Jayasekera S, Kaur L, Molan AL, Garg ML, Moughan PJ, 'Effects of season and plantation on phenolic content of unfermented and fermented Sri Lankan tea', Food Chemistry, 152 546-551 (2014) [C1]

The effects of season and plantation on the polyphenol content of Camellia sinensis (tea) leaves were determined. Aqueous and organic extracts of freeze-dried fresh (unfermented) ... [more]

The effects of season and plantation on the polyphenol content of Camellia sinensis (tea) leaves were determined. Aqueous and organic extracts of freeze-dried fresh (unfermented) and black (fully-fermented) tea leaves were prepared for a structured set of samples (fermented and unfermented teas from six high-, mid- and low-grown plantations; fermented and unfermented teas from two harvesting seasons from four highland plantations), collected from the main tea-growing regions in Sri Lanka. Total catechin content and amounts of individual catechins, flavonols and theaflavins were determined by HPLC. Mean values for the phenolic constituents were generally significantly higher (p < 0.05) with solvent extraction. The mean values for total catechins, total flavonols and caffeine in the aqueous extracts from unfermented teas were 10.6%, 1.5% and 2.9%, respectively. For both unfermented and fermented tea leaves, a significant (p < 0.05) interaction between plantation and season was observed for phenolic constituents. Ferric reducing antioxidant power was positively (p < 0.05) correlated with (-)-epicatechin gallate and total phenolic contents. © 2013 Elsevier Ltd. All rights reserved.

DOI 10.1016/j.foodchem.2013.12.005
Citations Scopus - 9
2014 Hristova K, Shiue I, Pella D, Singh RB, Chaves H, Basu TK, et al., 'Prevention strategies for cardiovascular diseases and diabetes mellitus in developing countries: World Conference of Clinical Nutrition 2013', Nutrition, (2014) [C2]
DOI 10.1016/j.nut.2013.12.013
Citations Scopus - 7Web of Science - 1
2014 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'The association between dietary patterns and type 2 diabetes: a systematic review and meta-analysis of cohort studies', JOURNAL OF HUMAN NUTRITION AND DIETETICS, 27 251-260 (2014) [C1]
DOI 10.1111/jhn.12139
Citations Scopus - 29Web of Science - 24
Co-authors Elizabeth Stojanovski, Mark Mcevoy
2014 Thomas J, Garg ML, Smith DW, 'Dietary resveratrol supplementation normalizes gene expression in the hippocampus of streptozotocin-induced diabetic C57Bl/6 mice', Journal of Nutritional Biochemistry, 25 313-318 (2014) [C1]

Diabetes is associated with cognitive impairment and brain aging, with alterations in hippocampal neurogenesis and synaptic plasticity implicated in these changes. As the prevalen... [more]

Diabetes is associated with cognitive impairment and brain aging, with alterations in hippocampal neurogenesis and synaptic plasticity implicated in these changes. As the prevalence of diabetes continues to rise, readily implemented strategies are increasingly needed in order to protect the brain's cognitive functions. One possibility is resveratrol (RES) (3,5,4- trihydroxystilbene), a polyphenol of the phytoalexin family that has been shown to be protective in a number of neuropathology paradigms. In the present study, we sought to determine whether dietary supplementation with RES has potential for the protection of cognitive functions in diabetes. Diabetes was induced using streptozotocin, and once stable, animals received AIN93G rodent diet supplemented with RES for 6 weeks. Genome-wide expression analysis was conducted on the hippocampus and genes of interest were confirmed by quantitative, real-time polymerase chain reaction. Genome-wide gene expression analysis of the hippocampus revealed that RES supplementation of the diabetic group resulted in 481differentially expressed genes compared to non-supplemented diabetic mice. Intriguingly, gene expression that was previously found significantly altered in the hippocampus of diabetic mice, and that is implicated in neurogenesis and synaptic plasticity (Hdac4, Hat1, Wnt7a, ApoE), was normalized following RES supplementation. In addition, pathway analysis revealed Jak-Stat signaling was the most significantly enriched pathway. The Jak-Stat pathway induces a pro-inflammatory signaling cascade, and we found most genes involved in this cascade (e.g. Il15, Il22, Socs2, Socs5) had significantly lower expression following RES supplementation. These data indicate RES could be neuroprotective and beneficial for the maintenance of cognitive function in diabetes. © 2014 Elsevier Inc.

DOI 10.1016/j.jnutbio.2013.11.005
Citations Scopus - 14Web of Science - 13
Co-authors Douglas Smith
2014 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Macronutrient intake and type 2 diabetes risk in middle-aged Australian women. Results from the Australian Longitudinal Study on Women's Health', PUBLIC HEALTH NUTRITION, 17 1587-1594 (2014) [C1]
DOI 10.1017/S1368980013001870
Citations Scopus - 10Web of Science - 8
Co-authors Elizabeth Stojanovski, Mark Mcevoy
2014 Jameel F, Phang M, Wood LG, Garg ML, 'Acute effects of feeding fructose, glucose and sucrose on blood lipid levels and systemic inflammation.', Lipids in Health and Disease, 13 1-7 (2014) [C1]
DOI 10.1186/1476-511x-13-195
Citations Scopus - 8Web of Science - 8
Co-authors Lisa Wood
2014 Hristova K, Pella D, Singh RB, Dimitrov BD, Chaves H, Juneja L, et al., 'Sofia declaration for prevention of cardiovascular diseases and type 2 diabetes mellitus: A scientific statement of the international college of cardiology and international college of nutrition', World Heart Journal, 6 89-106 (2014) [C1]

Background: There has been persistent emphasis from various health agencies including United Nations on the prevention of cardiovascular diseases (CVDs) and other chronic diseases... [more]

Background: There has been persistent emphasis from various health agencies including United Nations on the prevention of cardiovascular diseases (CVDs) and other chronic diseases. This review focusses on the emergence of CVDs and other chronic diseases as well as on modern strategies for their prevention. Methods: A systematic and narrative review was conducted using such reference databases as MEDLINE (PubMed), Web of Science and EBSCO, with additional secondary sources and grey literature searching. Opinions of experts were also sought and discussions followed. Results: The prevalence of primary risk factors for most chronic diseases is rapidly increasing in low and middle income populations due to the on-going economic development and progress. There is a decrease in such risk factors in the developed countries as due to education and adoption of preventive strategies result in a reduction in CVD mortality. Hypertension (5-10%), type 2 diabetes (3- 5%) and CAD (3-4%) are very low in the adult rural populations of India, China, and in the African subcontinent which has less economic development. It seems that it is not poverty, but the lack of health education, possibly due to ineffective policies of national and local governments. In urban and immigrant populations of India and China, which are economically better off, NCDs are significantly higher than they are in some of the highincome populations. Health education and promotion of healthier lifestyle and behaviour appear to be important for prevention in such countries. Conclusion: These findings may require modification of the existing American and European guidelines, proposed for the prevention of CVDs and other chronic diseases, in highincome populations. © 2014 Nova Science Publishers, Inc.

Citations Scopus - 14
2014 Guest J, Grant R, Garg M, Mori TA, Croft KD, Bilgin A, 'Cerebrospinal fluid levels of inflammation, oxidative stress and NAD(+) are linked to differences in plasma carotenoid concentrations', JOURNAL OF NEUROINFLAMMATION, 11 (2014) [C1]
DOI 10.1186/1742-2094-11-117
Citations Scopus - 2Web of Science - 5
2014 B Singh R, K Singh A, Mori H, Pella D, K Basu T, Ozimek L, et al., 'A Tribute to Nutrio-Diabetologist; Shanti S. Rastogi MBBS, MD, FRCP, FICN, FICC', The Open Nutraceuticals Journal, 7 39-43 (2014) [C2]
DOI 10.2174/1876396001407010039
2014 Drever J, Veysey M, Lucock MD, Niblett S, King K, MacDonald-Wicks L, Garg ML, 'Association between n-3 PUFA and blood lipid profile in older Australians.', Journal of Nutrition & Intermediary Metabolism, 1 31-31 (2014)
Co-authors Martin Veysey, Lesley Wicks, Katrina King, Mark Lucock
2014 Abbott K, Veysey M, Lucock MD, Niblett S, King K, MacDonald-Wicks L, Garg ML, 'N-3 pufa status is inversely associated with type 2 diabetes mellitus in older Australians.', Journal of Nutrition & Intermediary Metabolism, 1 31-31 (2014)
Co-authors Katrina King, Lesley Wicks, Martin Veysey, Mark Lucock
2014 Mingay E, Veysey M, Lucock MD, Niblett S, King K, Patterson A, Garg ML, 'Erythrocyte long chain n-3 pufa level is a predictor of body weight status in older Australians.', Journal of Nutrition & Intermediary Metabolism, 1 8-9 (2014)
Co-authors Katrina King, Amanda Patterson, Mark Lucock, Martin Veysey
2014 Olliver M, Veysey M, Lucock MD, Niblett S, King K, MacDonald-Wicks L, Garg ML, 'Erythrocyte n-3pufa levels predict inflammatory status in older Australians.', Journal of Nutrition & Intermediary Metabolism, 1 10-10 (2014)
Co-authors Katrina King, Lesley Wicks, Mark Lucock, Martin Veysey
2014 Rose M, Veysey M, Lucock MD, Niblett S, King K, Baines S, Garg ML, 'N-3 pufa status predicts non-alcoholic fatty liver disease (NAFLD) in older Australians.', Journal of Nutrition & Intermediary Metabolism, 1 9-9 (2014)
Co-authors Surinder Baines, Martin Veysey, Mark Lucock, Katrina King
2014 Albert BB, Derraik JGB, Brennan CM, Biggs JB, Smith GC, Garg ML, et al., 'Higher omega-3 index is associated with increased insulin sensitivity and more favourable metabolic profile in middle-aged overweight men', SCIENTIFIC REPORTS, 4 (2014) [C1]
DOI 10.1038/srep06697
Citations Scopus - 21Web of Science - 19
2014 Phang M, Scorgie FE, Seldon M, Garg ML, Lincz LF, 'Reduction of prothrombin and Factor V levels following supplementation with omega-3 fatty acids is sex dependent: A randomised controlled study', Journal of Nutritional Biochemistry, 25 997-1002 (2014) [C1]

© 2014 Elsevier Inc. Background: LCn-3PUFA comprised of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) offer cardioprotection involving a decrease in coagulant activi... [more]

© 2014 Elsevier Inc. Background: LCn-3PUFA comprised of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) offer cardioprotection involving a decrease in coagulant activity; however, the evidence is equivocal. We have previously demonstrated that the acute (24. h) effects and chronic (4. weeks) effects of LCn-3PUFA supplementation on platelet aggregation in human subjects are sex specific. This study investigated the mechanisms of the sex-dependent effects of LCn-3PUFA with 4. weeks supplementation of EPA-rich vs. DHA-rich oils on procoagulant and platelet activity in healthy subjects. Design: A double-blinded, placebo-controlled randomised trial was conducted in 94 healthy adults: male (. n=41) and female (. n=53). Platelet coagulation parameters including factors I, II, V, VII, VIII, IX, X, vWF:Ag and endogenous thrombin potential were measured at baseline and 4. weeks postsupplementation with EPA-rich or DHA-rich oil capsules. Results: We have previously reported that platelet aggregation is specifically reduced by supplementation with EPA in males and DHA in females. This sex-specific effect was also observed for decreases in plasma levels of Factor II (-7.9±3.8%, P=.026), Factor V (-6.5±4.5%, P=.022) and vWF:Ag (-7.3±2.1%, P=.034) and was most pronounced in males supplemented with EPA. In contrast, DHA-mediated reduction in platelet aggregation in females was not accompanied by any significant changes in the coagulation parameters tested. Conclusion: Significant interactions between sex and specific LCn-3PUFA exist to reduce procoagulant activity differentially in males vs. females and could have profound effects on managing risk of thrombotic disease.

DOI 10.1016/j.jnutbio.2014.05.001
Citations Scopus - 4Web of Science - 3
Co-authors Lisa Lincz
2014 Alhazmi A, Stojanovski E, McEvoy M, Brown W, Garg ML, 'Diet quality score is a predictor of type 2 diabetes risk in women: the Australian Longitudinal Study on Women's Health.', Br J Nutr, 112 945-951 (2014) [C1]
DOI 10.1017/S0007114514001688
Citations Scopus - 9Web of Science - 9
Co-authors Mark Mcevoy, Elizabeth Stojanovski
2013 Munro IA, Garg ML, 'Prior supplementation with long chain omega-3 polyunsaturated fatty acids promotes weight loss in obese adults: a double-blinded randomised controlled trial.', Food &amp; function, 4 650-658 (2013) [C1]

Obesity has been linked with low levels of ¿-3 fatty acids. Generally, intervention studies have failed to establish benefits of supplementation with ¿-3PUFA in reducing body we... [more]

Obesity has been linked with low levels of ¿-3 fatty acids. Generally, intervention studies have failed to establish benefits of supplementation with ¿-3PUFA in reducing body weight or fat mass in humans. The aim of this study was to investigate whether supplementation with LC¿-3PUFA alone, then consumed concomitantly with a very low energy diet (VLED), facilitated weight loss, improvements in blood lipids and positive changes to inflammatory mediators. This was a double blind randomised controlled trial with two parallel groups. For 4 weeks of prior supplementation, one group consumed 6 × 1 g capsules per day monounsaturated oil (placebo), the other group consumed 6 × 1 g capsules per day LC¿-3PUFA (fish oil) each comprising 70 mg EPA and 270 mg DHA, while consuming their usual diet. Each group continued with their supplements for another 4 weeks while both groups followed a VLED regimen (n = 19 placebo, n = 20 fish oil). Fasting blood samples, anthropometric measurements and 3-day food diaries were collected at baseline, at 4 weeks and at 8 weeks. At 4 weeks levels of EPA and DHA increased two-fold in the fish oil group (P < 0.001), with no significant changes to anthropometric measurements for either group. At 8 weeks a significant 3-way interaction between time, group and gender was observed for percentage reduction in weight, F(1,35) = 5.55, P = 0.024, and BMI, F(1,35) = 5.3, P = 0.027 with a greater percentage decrease for females in FO compared to PB for weight (-7.21% vs.-5.82%) and BMI (-7.43% vs.-5.91%) respectively (P < 0.05 for both). It would appear that supplementation with LC¿-3PUFA had a time dependent effect on weight loss in females.

DOI 10.1039/c3fo60038f
Citations Scopus - 20Web of Science - 20
2013 Guest J, Bilgin A, Morris MJ, Garg ML, Pearce R, 'Suboptimal Omega-3 Levels in Australian Adolescents.', International Journal of Child Health and Nutrition, 2 309-315 (2013) [C1]
DOI 10.6000/1929-4247.2013.02.04.4
2013 Guest J, Garg M, Bilgin A, Grant R, 'Relationship between central and peripheral fatty acids in humans', Lipids in Health and Disease, 12 (2013) [C1]
DOI 10.1186/1476-511X-12-79
Citations Scopus - 21Web of Science - 20
2013 Phang M, Lincz LF, Garg ML, 'Eicosapentaenoic and Docosahexaenoic Acid Supplementations Reduce Platelet Aggregation and Hemostatic Markers Differentially in Men and Women', JOURNAL OF NUTRITION, 143 457-463 (2013) [C1]
DOI 10.3945/jn.112.171249
Citations Scopus - 30Web of Science - 30
Co-authors Lisa Lincz
2013 Kumar S, Sutherland F, Lee JMS, Robinson T, Heck PM, Wong MCG, et al., 'Effects of high dose intravenous fish oil on human atrial electrophysiology: Implications for possible anti- and pro-arrhythmic mechanisms in atrial fibrillation', International Journal of Cardiology, 168 2754-2760 (2013) [C1]
DOI 10.1016/j.ijcard.2013.03.053
Citations Scopus - 6Web of Science - 5
2013 Kumar S, Sutherland F, Stevenson I, Lee JMS, Garg ML, Sparks PB, 'Effects of long-term omega-3 polyunsaturated fatty acid supplementation on paroxysmal atrial tachyarrhythmia burden in patients with implanted pacemakers: Results from a prospective randomised study', International Journal of Cardiology, 168 3812-3817 (2013) [C1]
DOI 10.1016/j.ijcard.2013.06.030
Citations Scopus - 3Web of Science - 3
2013 Zaman K, McArthur JO, Abboud MN, Ahmad ZI, Garg ML, Petocz P, Samman S, 'Iron supplementation decreases plasma zinc but has no effect on plasma fatty acids in non-anemic women', Nutrition Research, 33 272-278 (2013) [C1]
DOI 10.1016/j.nutres.2013.02.001
Citations Scopus - 7Web of Science - 4
2013 Thomas J, Garg ML, Smith DW, 'Altered expression of histone and synaptic plasticity associated genes in the hippocampus of streptozotocin-induced diabetic mice', Metabolic Brain Disease, 28 613-618 (2013) [C1]
DOI 10.1007/s11011-013-9418-y
Citations Scopus - 10Web of Science - 8
Co-authors Douglas Smith
2013 Thomas J, Garg ML, Smith DW, 'Dietary supplementation with resveratrol and/or docosahexaenoic acid alters hippocampal gene expression in adult C57Bl/6 mice', Journal of Nutritional Biochemistry, 24 1735-1740 (2013) [C1]

The hippocampus is an important brain structure for multiple cognitive functions, including memory formation. It is particularly sensitive to insults, such as stress, ischemia, an... [more]

The hippocampus is an important brain structure for multiple cognitive functions, including memory formation. It is particularly sensitive to insults, such as stress, ischemia, and aging; all of these can affect hippocampal and therefore cognitive function. To understand the potential of diet for the preservation of hippocampal function, we investigated the effects of dietary supplementation with resveratrol (RES) or docosahexaenoic acid (DHA), or their combination, on hippocampal gene expression in adult C57BL/6 mice. Animals in the supplemented group received either 50 mg/kg/day of RES or DHA, while the combination group received 50 mg/kg/day of each supplement. Dietary supplements were mixed with the AIN93G diet, and supplementation lasted 6 weeks. The control group received AIN93G diet alone for the same period. At the end of the experiment, the hippocampi were processed for genome-wide gene expression and pathway analyses. Most of the genes that were significantly altered were associated with inflammatory responses as determined by pathway analysis. RES-supplemented animals showed decreased expression of IL-6 ( P=001), MAPKapk2 ( P=015), and increased expression for PI3. KR2 ( P=034) and Wnt7a ( P=004) expression. DHA-supplemented animals showed a decreased IL-6 ( P=003) and an increased Wnt7a ( P=003) expression. Animals on the combination diet showed a decreased IL-6 ( P=005) and Apolipoprotien E ( ApoE) ( P=035) expression. Our findings demonstrate that hippocampal gene expression is significantly altered by all three dietary supplementation regimes. Moreover, our analysis indicates that RES and DHA likely exert their beneficial effects through antiinflammatory mechanisms. © 2013 Elsevier Inc.

DOI 10.1016/j.jnutbio.2013.03.002
Citations Scopus - 9Web of Science - 7
Co-authors Douglas Smith
2013 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Dietary restriction and exercise improve airway inflammation and clinical outcomes in overweight and obese asthma: a randomized trial', Clinical and Experimental Allergy, 43 36-49 (2013) [C1]
DOI 10.1111/cea.12004
Citations Scopus - 58Web of Science - 55
Co-authors Philip Morgan, Robin Callister, Hayley Scott, Peter Gibson, Lisa Wood
2013 Fulton AS, Hill AM, Williams MT, Howe PR, Frith PA, Wood LG, et al., 'Feasibility of omega-3 fatty acid supplementation as an adjunct therapy for people with chronic obstructive pulmonary disease: study protocol for a randomized controlled trial', TRIALS, 14 (2013) [C3]
DOI 10.1186/1468-6708-14-107
Citations Scopus - 7Web of Science - 8
Co-authors Lisa Wood, Peter Howe
2013 Munro IA, Garg ML, 'Dietary supplementation with long chain omega-3 polyunsaturated fatty acids and weight loss in obese adults', OBESITY RESEARCH & CLINICAL PRACTICE, 7 E173-E181 (2013) [C1]
DOI 10.1016/j.orcp.2011.11.001
Citations Scopus - 20Web of Science - 16
2012 Garg ML, Wood LG, 'Preface', Nutrition and Physical Activity in Inflammatory Diseases, (2012)
Co-authors Lisa Wood
2012 Wood LG, Garg ML, Smart JM, Scott HA, Barker D, Gibson PG, 'Manipulating antioxidant intake in asthma: A randomized controlled trial', American Journal of Clinical Nutrition, 96 534-543 (2012) [C1]
DOI 10.3945/ajcn.111.032623
Citations Scopus - 56Web of Science - 53
Co-authors Hayley Scott, Peter Gibson, Lisa Wood
2012 Munro IA, Garg ML, 'Dietary supplementation with n-3 PUFA does not promote weight loss when combined with a very-low-energy diet', British Journal of Nutrition, 108 1466-1474 (2012) [C1]
Citations Scopus - 26Web of Science - 25
2012 Saunders AV, Davis BC, Garg ML, 'Omega-3 polyunsaturated fatty acids and vegetarian diets', MJA Open, 1 22-26 (2012) [C3]
Citations Scopus - 8Web of Science - 1
2012 Phang M, Sinclair AJ, Lincz L, Garg ML, 'Gender-specific inhibition of platelet aggregation following omega-3 fatty acid supplementation', Nutrition Metabolism and Cardiovascular Diseases, 22 109-114 (2012) [C1]
Citations Scopus - 25Web of Science - 23
Co-authors Lisa Lincz
2012 Burrows TL, Berthon B, Garg ML, Collins CE, 'A comparative validation of a child food frequency questionnaire using red blood cell membrane fatty acids', European Journal of Clinical Nutrition, 66 825-829 (2012) [C1]
Citations Scopus - 27Web of Science - 27
Co-authors Clare Collins, Tracy Burrows
2012 Phang M, Lincz L, Seldon M, Garg ML, 'Acute supplementation with eicosapentaenoic acid reduces platelet microparticle activity in healthy subjects', Journal of Nutritional Biochemistry, 23 1128-1133 (2012) [C1]
Citations Scopus - 12Web of Science - 10
Co-authors Lisa Lincz
2012 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Relationship between body composition, inflammation and lung function in overweight and obese asthma', Respiratory Research, 13 1-10 (2012) [C1]
Citations Scopus - 21Web of Science - 21
Co-authors Peter Gibson, Hayley Scott, Philip Morgan, Robin Callister, Lisa Wood
2012 Wang X-D, Song Y, Sheahan MB, Garg ML, Rose RJ, 'From embryo sac to oil and protein bodies: Embryo development in the model legume Medicago truncatula', New Phytologist, 193 327-338 (2012) [C1]
DOI 10.1111/j.1469-8137.2011.03925.x
Citations Scopus - 6Web of Science - 4
Co-authors Ray Rose
2012 Alhazmi AH, Stojanovski E, McEvoy MA, Garg ML, 'Macronutrient intakes and development of type 2 diabetes: A systematic review and meta-analysis of cohort studies', Journal of the American College of Nutrition, 31 243-258 (2012) [C1]
Citations Scopus - 23Web of Science - 21
Co-authors Mark Mcevoy, Elizabeth Stojanovski
2012 Kumar S, Sutherland F, Morton JB, Lee G, Morgan J, Wong J, et al., 'Long-term omega-3 polyunsaturated fatty acid supplementation reduces the recurrence of persistent atrial fibrillation after electrical cardioversion', Heart Rhythm, 9 483-491 (2012) [C1]
Citations Scopus - 38Web of Science - 29
2011 Munro IA, Bore MR, Munro D, Garg ML, 'Using personality as a predictor of diet induced weight loss and weight management', International Journal of Behavioral Nutrition and Physical Activity, 8 (2011) [C1]
DOI 10.1186/1479-5868-8-129
Citations Scopus - 11Web of Science - 8
Co-authors Miles Bore
2011 Kumar S, Sutherland F, Rosso R, Teh AW, Lee G, Heck PM, et al., 'Effects of chronic omega-3 polyunsaturated fatty acid supplementation on human atrial electrophysiology', Heart Rhythm, 8 562-568 (2011) [C1]
DOI 10.1016/j.hrthm.2010.12.017
Citations Scopus - 31Web of Science - 28
2011 Kumar S, Sutherland F, Wheeler M, Heck PM, Lee G, Teh AW, et al., 'Effects of chronic omega-3 polyunsaturated fatty acid supplementation on human atrial mechanical function after reversion of atrial arrhythmias to sinus rhythm: Reversal of tachycardia-mediated atrial cardiomyopathy with fish oils', Heart Rhythm, 8 643-649 (2011) [C1]
DOI 10.1016/j.hrthm.2011.01.014
Citations Scopus - 18Web of Science - 12
2011 Burrows TL, Collins CE, Garg ML, 'Omega-3 index, obesity and insulin resistance in children', International Journal of Pediatric Obesity, 6 e532-e539 (2011) [C1]
DOI 10.3109/17477166.2010.549489
Citations Scopus - 40Web of Science - 34
Co-authors Tracy Burrows, Clare Collins
2011 Munro IA, Garg ML, 'Weight loss and metabolic profiles in obese individuals using two different approaches', Food & Function, 2 611-616 (2011) [C1]
DOI 10.1039/c1fo10143a
Citations Scopus - 4Web of Science - 5
2011 Kumar S, Sutherland F, Teh AW, Heck PM, Lee G, Garg ML, Sparks PB, 'Effects of chronic omega-3 polyunsaturated fatty acid supplementation on human pulmonary vein and left atrial electrophysiology in paroxysmal atrial fibrillation', American Journal of Cardiology, 108 531-535 (2011) [C1]
DOI 10.1016/j.amjcard.2011.03.082
Citations Scopus - 24Web of Science - 18
2011 Wood LG, Garg ML, Gibson PG, 'A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma', Journal of Allergy and Clinical Immunology, 127 1133-1140 (2011) [C1]
DOI 10.1016/j.jaci.2011.01.036
Citations Scopus - 82Web of Science - 73
Co-authors Lisa Wood, Peter Gibson
2011 Phang M, Lazarus S, Wood LG, Garg ML, 'Diet and thrombosis risk: Nutrients for prevention of thrombotic disease', Seminars in Thrombosis and Hemostasis, 37 199-208 (2011) [C1]
DOI 10.1055/s-0031-1273084
Citations Scopus - 32Web of Science - 30
Co-authors Lisa Wood
2011 Kaur G, Cameron-Smith D, Garg ML, Sinclair AJ, 'Docosapentaenoic acid (22:5n-3): A review of its biological effects', Progress in Lipid Research, 50 28-34 (2011) [C1]
DOI 10.1016/j.plipres.2010.07.004
Citations Scopus - 132Web of Science - 119
2011 Scott HA, Gibson PG, Garg ML, Wood LG, 'Airway inflammation is augmented by obesity and fatty acids in asthma', European Respiratory Journal, 38 594-602 (2011) [C1]
DOI 10.1183/09031936.00139810
Citations Scopus - 97Web of Science - 85
Co-authors Peter Gibson, Hayley Scott, Lisa Wood
2010 Wood LG, Wark PA, Garg ML, 'Antioxidant and anti-inflammatory effects of resveratrol in airway disease', Antioxidants & Redox Signaling, 13 1535-1548 (2010) [C1]
DOI 10.1089/ars.2009.3064
Citations Scopus - 58Web of Science - 59
Co-authors Lisa Wood, Peter Wark
2010 Garg ML, Wood LG, 'Functional foods and cardiovascular disease', Cardiology in General Practice, 14 24-25 (2010) [C2]
Co-authors Lisa Wood
2010 Kaur G, Begg DP, Barr D, Garg ML, Cameron-Smith D, Sinclair AJ, 'Short-term docosapentaenoic acid (22:5 n-3) supplementation increases tissue docosapentaenoic acid, DHA and EPA concentrations in rats', British Journal of Nutrition, 103 32-37 (2010) [C1]
DOI 10.1017/S0007114509991334
Citations Scopus - 39Web of Science - 38
2010 Plunkett BA, Callister R, Watson TA, Garg ML, 'Dietary antioxidant restriction affects the inflammatory response in athletes', British Journal of Nutrition, 103 1179-1184 (2010) [C1]
DOI 10.1017/S0007114509993011
Citations Scopus - 5Web of Science - 4
Co-authors Robin Callister
2010 Jayasekera S, Molan AL, Garg ML, Moughan PJ, 'Variation in antioxidant potential and total polyphenol content of fresh and fully-fermented Sri Lankan tea', Food Chemistry, 125 536-541 (2010) [C1]
DOI 10.1016/j.foodchem.2010.09.045
Citations Scopus - 32Web of Science - 19
2010 Koppers AJ, Garg ML, Aitken RJ, 'Stimulation of mitochondrial reactive oxygen species production by unesterified, unsaturated fatty acids in defective human spermatozoa', Free Radical Biology and Medicine, 48 112-119 (2010) [C1]
DOI 10.1016/j.freeradbiomed.2009.10.033
Citations Scopus - 78Web of Science - 80
Co-authors John Aitken
2010 Begg DP, Sinclair AJ, Stahl LA, Garg ML, Jois M, Weisinger RS, 'Dietary protein level interacts with omega-3 polyunsaturated fatty acid deficiency to induce hypertension', American Journal of Hypertension, 23 125-128 (2010) [C1]
DOI 10.1038/ajh.2009.198
Citations Scopus - 18Web of Science - 15
2010 De Bock CE, Garg ML, Scott NM, Sakoff JA, Scorgie FE, Ackland S, Lincz L, 'Association of thymidylate synthase enhancer region polymorphisms with thymidylate synthase activity in vivo', Pharmacogenomics Journal, 1-8 (2010) [C1]
DOI 10.1038/tpj.2010.43
Citations Scopus - 12Web of Science - 11
Co-authors Jennette Sakoff, Lisa Lincz, Stephen Ackland
2009 Watson JF, Collins CE, Sibbritt DW, Dibley MJ, Garg ML, 'Reproducibility and comparative validity of a food frequency questionnaire for Australian children and adolescents', International Journal of Behavioral Nutrition and Physical Activity, 6 1-17 (2009) [C1]
DOI 10.1186/1479-5868-6-62
Citations Scopus - 96Web of Science - 86
Co-authors Clare Collins
2009 Burrows TL, Warren JM, Colyvas KJ, Garg ML, Collins CE, 'Validation of overweight children's fruit and vegetable intake using plasma carotenoids', Obesity, 17 162-168 (2009) [C1]
DOI 10.1038/oby.2008.495
Citations Scopus - 60Web of Science - 49
Co-authors Tracy Burrows, Clare Collins, Kim Colyvas
2009 Saedi Some Olia A, Wood LG, Garg ML, Gibson PG, Wark PA, 'Anti-inflammatory effects of long-chain n-3 PUFA in rhinovirus-infected cultured airway epithelial cells', British Journal of Nutrition, 101 533-540 (2009) [C1]
DOI 10.1017/s0007114508025798
Citations Scopus - 16Web of Science - 13
Co-authors Peter Gibson, Lisa Wood, Peter Wark
2009 Micallef MA, Munro IA, Phang M, Garg ML, 'Plasma n-3 polyunsaturated fatty acids are negatively associated with obesity', British Journal of Nutrition, 102 1370-1374 (2009) [C1]
DOI 10.1017/s0007114509382173
Citations Scopus - 87Web of Science - 84
2009 Micallef MA, Garg ML, 'Anti-inflammatory and cardioprotective effects of n-3 polyunsaturated fatty acids and plant sterols in hyperlipidemic individuals', Atherosclerosis, 204 476-482 (2009) [C1]
DOI 10.1016/j.atherosclerosis.2008.09.020
Citations Scopus - 90Web of Science - 88
2009 Wood LG, Scott HA, Garg ML, Gibson PG, 'Innate immune mechanisms linking non-esterified fatty acids and respiratory disease', Progress in Lipid Research, 48 27-43 (2009) [C1]
DOI 10.1016/j.plipres.2008.10.001
Citations Scopus - 29Web of Science - 26
Co-authors Peter Gibson, Lisa Wood, Hayley Scott
2009 Phang M, Garg ML, Sinclair AJ, 'Inhibition of platelet aggregation by omega-3 polyunsaturated fatty acids is gender specific-Redefining platelet response to fish oils', Prostaglandins Leukotrienes and Essential Fatty Acids, 81 35-40 (2009) [C1]
DOI 10.1016/j.plefa.2009.05.001
Citations Scopus - 32Web of Science - 29
2009 Clayton EH, Hanstock T, Hirneth SJ, Kable CJ, Garg ML, Hazell P, 'Reduced mania and depression in juvenile bipolar disorder associated with long-chain omega-3 polyunsaturated fatty acid supplementation', European Journal of Clinical Nutrition, 63 1037-1040 (2009) [C1]
DOI 10.1038/ejcn.2008.81
Citations Scopus - 71Web of Science - 56
Co-authors Tanya Hanstock
2009 Micallef MA, Munro IA, Garg ML, 'An inverse relationship between plasma n-3 fatty acids and C-reactive protein in healthy individuals', European Journal of Clinical Nutrition, 63 1154-1156 (2009) [C1]
DOI 10.1038/ejcn.2009.20
Citations Scopus - 66Web of Science - 57
2009 Saedi Some Olia A, Wood LG, Garg ML, Gibson PG, Wark PA, 'Lycopene enrichment of cultured airway epithelial cells decreases the inflammation induced by rhinovirus infection and lipopolysaccharide', Journal of Nutritional Biochemistry, 20 577-585 (2009) [C1]
DOI 10.1016/j.jnutbio.2008.06.001
Citations Scopus - 34Web of Science - 29
Co-authors Peter Wark, Lisa Wood, Peter Gibson
2009 Micallef MA, Garg ML, 'Beyond blood lipids: Phytosterols, statins and omega-3 polyunsaturated fatty acid therapy for hyperlipidemia', Journal of Nutritional Biochemistry, 20 927-939 (2009) [C1]
DOI 10.1016/j.jnutbio.2009.06.009
Citations Scopus - 51Web of Science - 36
2008 Saedi Some Olia A, Wood LG, Garg ML, Gibson PG, Wark PA, 'Supplementation of long chain N-3 polyunsaturated fatty acids increases the utilization of lycopene in cultured airway epithelial cells', Journal of Food Lipids, 15 421-432 (2008) [C1]
DOI 10.1111/j.1745-4522.2008.00130.x
Citations Scopus - 8Web of Science - 6
Co-authors Lisa Wood, Peter Gibson, Peter Wark
2008 Wood LG, Garg ML, Powell H, Gibson PG, 'Lycopene-rich treatments modify noneosinophilic airway inflammation in asthma: Proof of concept', Free Radical Research, 42 94-102 (2008) [C1]
DOI 10.1080/10715760701767307
Citations Scopus - 51Web of Science - 47
Co-authors Peter Gibson, Lisa Wood
2008 Micallef MA, Garg ML, 'The lipid-lowering effects of phytosterols and (n-3) polyunsaturated fatty acids are synergistic and complementary in hyperlipidemic men and women', Journal of Nutrition, 138 1086-1090 (2008) [C1]
Citations Scopus - 60Web of Science - 55
2008 Clayton EH, Hanstock T, Hirneth SJ, Kable CJ, Garg ML, Hazell P, 'Long-chain omega-3 polyunsaturated fatty acids in the blood of children and adolescents with juvenile bipolar disorder', Lipids, 43 1031-1038 (2008) [C1]
DOI 10.1007/s11745-008-3224-z
Citations Scopus - 48Web of Science - 39
Co-authors Tanya Hanstock
2008 Wood LG, Garg ML, Blake RJ, Simpson JL, Gibson PG, 'Oxidized vitamin E and glutathione as markers of clinical status in asthma', Clinical Nutrition, 27 579-586 (2008) [C1]
DOI 10.1016/j.clnu.2007.12.002
Citations Scopus - 23Web of Science - 19
Co-authors Lisa Wood, Jodie Simpson, Peter Gibson
2008 Shi Z, Hu XS, Yuan BJ, Gibson RE, Dai Y, Garg ML, 'Association between magnesium: Iron intake ratio and diabetes in Chinese adults in Jiangsu Province', Diabetic Medicine, 25 1164-1170 (2008) [C1]
DOI 10.1111/j.1464-5491.2008.02558.x
Citations Scopus - 9Web of Science - 9
2008 Shi Z, Hu X, He K, Yuan B, Garg ML, 'Joint association of magnesium and iron intake with anemia among Chinese adults', Nutrition, 24 977-984 (2008) [C1]
DOI 10.1016/j.nut.2008.05.002
Citations Scopus - 15Web of Science - 15
2007 Garg ML, Blake RJ, Clayton E, Munro IA, MacDonald-Wicks LK, Singh H, Moughan PJ, 'Consumption of an n-3 polyunsaturated fatty acid-enriched dip modulates plasma lipid profile in subjects with diabetes type II', European Journal of Clinical Nutrition, 61 1312-1317 (2007) [C1]
DOI 10.1038/sj.ejcn.1602650
Citations Scopus - 21Web of Science - 18
Co-authors Lesley Wicks
2007 Garg ML, 'Nutrition and arthritis', Nutrition & Dietetics, 64 301-302 (2007) [C3]
DOI 10.1111/j.1747-0080.2007.00173.x
2007 Clayton EH, Hanstock T, Garg ML, Hazell P, 'Long chain omega-3 polyunsaturated fatty acids in the treatment of psychiatric illnesses in children and adolescents', Acta Neuropsychiatrica, 19 92-103 (2007) [C1]
DOI 10.1111/j.1601-5215.2007.00189.x
Citations Scopus - 24Web of Science - 22
Co-authors Tanya Hanstock
2007 Lincz L, Scorgie FE, Garg ML, Ackland S, 'Reply to the letter to the editor 'Classification of thymidylate synthase gene enhancer region polymorphisms'', International Journal of Cancer, 121 2581-2582 (2007) [C3]
DOI 10.1002/ijc.22987
Co-authors Lisa Lincz, Stephen Ackland
2007 Garg ML, Blake RJ, Wills RB, Clayton EH, 'Macadamia nut consumption modulates favourably risk factors for coronary artery disease in hypercholesterolemic subjects', Lipids, 42 583-587 (2007) [C1]
DOI 10.1007/s11745-007-3042-8
Citations Scopus - 37Web of Science - 40
Co-authors Ron Wills
2006 Garg ML, Leitch J, Blake RJ, Garg R, 'Long-Chain n-3 Polyunsaturated Fatty Acid Incorporation into Human Atrium Following Fish Oil Supplementation', Lipids, 41 1127-1132 (2006) [C1]
DOI 10.1007/s11745-006-5062-1
Citations Scopus - 18Web of Science - 16
2006 Garg ML, Wood LG, Singh H, Moughan PJ, 'Means of delivering recommended levels of long chain n-3 polyunsaturated fatty acids in human diets', Journal of Food Science, 71 R66-R71 (2006) [C1]
DOI 10.1111/j.1750-3841.2006.00033.x
Citations Scopus - 98Web of Science - 75
Co-authors Lisa Wood
2006 MacDonald-Wicks LK, Wood LG, Garg ML, 'Methodology for the determination of biological antioxidant capacity in vitro: A review', Journal of the Science of Food and Agriculture, 86 2046-2056 (2006) [C1]
DOI 10.1002/jsfa.2603
Citations Scopus - 169Web of Science - 145
Co-authors Lisa Wood, Lesley Wicks
2006 Wood LG, Gibson PG, Garg ML, 'A review of the methodology for assessing in vivo antioxidant capacity', Journal of the Science of Food and Agriculture, 86 2057-2066 (2006) [C1]
DOI 10.1002/jsfa.2604
Citations Scopus - 64Web of Science - 52
Co-authors Peter Gibson, Lisa Wood
2006 Ikeda EB, Collins CE, Alvaro F, Marshall G, Garg ML, 'Wellbeing and nutrition-related side effects in children undergoing chemotherapy', Nutrition & Diatetics, 63 227-239 (2006) [C1]
DOI 10.1111/j.1747-0080.2006.00107.x
Citations Scopus - 2
Co-authors Clare Collins
2005 Wood LG, Gibson PG, Garg ML, 'Circulating markers to assess nutritional therapy in cystic fibrosis', Clinica Chimica Acta, 353 13-29 (2005) [C1]
DOI 10.1016/j.cccn.2004.11.002
Citations Scopus - 8Web of Science - 7
Co-authors Peter Gibson, Lisa Wood
2005 Watson TA, Callister R, Taylor RD, Sibbritt DW, MacDonald-Wicks LK, Garg ML, 'Antioxidant Restriction and Oxidative Stress in Short-Duration Exhaustive Exercise', Medicine & science in sports & exercise, 37 63-71 (2005) [C1]
DOI 10.1249/01.MSS.0000150016.46508.A1
Citations Scopus - 78Web of Science - 73
Co-authors Robin Callister, Lesley Wicks
2005 Wood LG, Garg ML, Blake RJ, Garcia-Caraballo S, Gibson PG, 'Airway and Circulating Levels of Carotenoids in Asthma and Healthy Controls', Journal of the American College of Nutrition, 24 448-455 (2005) [C1]
Citations Scopus - 43Web of Science - 39
Co-authors Lisa Wood, Peter Gibson
2005 Garg ML, 'Book Review : Flaxeed in Human Nutrition', Journal of the Science of Food and Agriculture, 85 1784 (2005) [C3]
2005 Watson TA, Blake RJ, Callister R, Garg ML, 'Antioxidant-restricted diet reduces plasma nonesterified fatty acids in trained athletes (communication)', Lipids, 40 433-435 (2005) [C3]
Co-authors Robin Callister
2005 Watson TA, Blake RJ, Callister R, Garg ML, 'Antioxidant-restricted diet reduces plasma nonesterified fatty acids in trained athletes', Lipids, 40 433-435 (2005) [C1]
DOI 10.1007/s11745-006-1401-5
Citations Scopus - 2Web of Science - 3
Co-authors Robin Callister
2005 Watson TA, MacDonald-Wicks LK, Garg ML, 'Oxidative stress and antioxidants in athletes undertaking regular exercise training', International Journal of Sport Nutrition and Exercise Metabolism, 15 131-146 (2005) [C1]
Citations Scopus - 47Web of Science - 44
Co-authors Lesley Wicks
2005 Wood LG, Garg ML, Simpson JL, Mori TA, Croft KD, Wark PA, Gibson PG, 'Induced sputum 8-isoprostane concentrations in inflammatory airway diseases', American Journal of Respiratory and Critical Care Medicine, 171 426-430 (2005) [C1]
DOI 10.1164/rccm.200408-1010OC
Citations Scopus - 69Web of Science - 58
Co-authors Lisa Wood, Peter Wark, Peter Gibson, Jodie Simpson
2005 Ikeda EB, Collins CE, Alvaro F, Marshall G, Garg ML, 'Lipid Peroxidation and Antioxidant Defenses in Pediatric Oncology Patients Undergoing Chemotherapy', Journal of Cancer Integrative Medicine, 3 41-50 (2005) [C1]
Citations Scopus - 1
Co-authors Clare Collins
2004 MacDonald-Wicks LK, Garg ML, 'Incorporation of n-3 fatty acids into plasma and liver lipids in rats: Importance of background dietary fat', Lipids, 39 545-551 (2004) [C1]
DOI 10.1007/s11745-004-1261-z
Citations Scopus - 18Web of Science - 17
Co-authors Lesley Wicks
2004 Lazarus S, Bowen K, Garg ML, 'Tomato juice and platelet aggregation in Type 2 diabetes', JAMA: The journal of the american medical association, 292 805-806 (2004) [C1]
DOI 10.1001/jama.292.7.805
Citations Scopus - 28Web of Science - 20
2004 Lazarus S, Garg ML, 'Tomato extracts inhibits human platelet aggregation in vitro without increasing basal cAMP levels', International Journal of Food Sciences and Nutrition, 55 249-256 (2004) [C1]
DOI 10.1080/09637480410001734003
Citations Scopus - 18Web of Science - 10
2003 Wood LG, Fitzgerald DA, Lee AK, Garg ML, 'Improved antioxidant and fatty acid status of patients with cystic-fibrosis after antioxidant supplementation is linked to improved lung function', American Journal of Clinical Nutrition, 77 150-159 (2003) [C1]
Citations Scopus - 73Web of Science - 66
Co-authors Lisa Wood
2003 Garg ML, Blake RJ, Wills RBH, 'Macadamia nut consumption lowers plasma total and LDL cholesterol levels in hypercholesterolemic men', JOURNAL OF NUTRITION, 133 1060-1063 (2003)
Citations Scopus - 82Web of Science - 64
Co-authors Ron Wills
2003 Garg ML, Blake RJ, Wills RB, 'Macadamia nut comsumption lowers plasma total and LDL cholesterol levels in hypercholesterolemic men', Journal of Nutrition, 133 1060-1063 (2003) [C1]
Co-authors Ron Wills
2003 Wood LG, Fitzgerald DA, Garg ML, 'Hypothesis: Vitamin E complements polyunsaturated fatty acids in essential fatty acid defiency in cystic fibrosis', American College of Nutrition Journal, 22 253-256 (2003) [C1]
Citations Scopus - 13Web of Science - 11
Co-authors Lisa Wood
2003 Wood LG, Gibson PG, Garg ML, 'Exhaled breath condensate contains more than only volatiles', The European Respiratory Journal, 22 1 (2003) [C3]
Citations Scopus - 5
Co-authors Peter Gibson, Lisa Wood
2003 MacDonald-Wicks LK, Garg ML, 'Vitamin E supplementation in the mitigation of carbon tetrachloride induced oxidative stress in rats', Journal of Nutritional Biochemistry, 14 177-186 (2003) [C1]
DOI 10.1016/S0955-2863(03)00003-2
Citations Scopus - 19Web of Science - 16
Co-authors Lesley Wicks
2002 Wood LG, Fitzgerald DA, Gibson PG, Cooper DM, Collins CE, Garg ML, 'Oxidative stress in cystic fibrosis: Dietary and metabolic factors. (Vol 20, pg 157, 2001)', JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 21 363-363 (2002)
Co-authors Peter Gibson, Lisa Wood, Clare Collins
2002 Warden RA, Noltorp RA, Bell CJ, O'Loughlin EV, Dunkley PR, Garg ML, 'Vitamin A Deficiency Changes Jejunal Mucosal Fatty Acid Profile in Rats', Journal of Clinical Biochemistry and Nutrition, 31 19-26 (2002) [C1]
Citations Scopus - 1Web of Science - 1
Co-authors Peter Dunkley
2002 MacDonald-Wicks LK, Garg ML, 'Modulation of carbon tetrachloride-induced oxidative stress by dietary fat in rats', The Journal of Nutritional Biochemistry, 13 87-95 (2002) [C1]
Citations Scopus - 17Web of Science - 14
Co-authors Lesley Wicks
2002 Garg ML, 'Macadamias for a healthy heart', Food Australia, 54 86 (2002) [C2]
2002 Wood LG, Fitzgerald DA, Gibson PG, Cooper DM, Garg ML, 'Erratum: Increased plasma fatty acid concentrations after respiratory exacerbations are associated with elevated oxidative stress in cystic fibrosis patients (American Journal of Clinical Nutrition (2002) 75 (668-675))', American Journal of Clinical Nutrition, 76 907 (2002)
Citations Scopus - 1
Co-authors Lisa Wood, Peter Gibson
2002 Wood LG, Fitzgerald DA, Gibson PG, Cooper DM, Collins CE, Garg ML, 'Erratum: Oxidative stress in cystic fibrosis: Dietary and metabolic factors (Journal of the American College of Nutrition (2001) 20:2 (157-165))', Journal of the American College of Nutrition, 21 363 (2002)
Co-authors Clare Collins, Lisa Wood, Peter Gibson
2002 Wood LG, Fitzgerald DA, Gibson PG, Cooper DM, Garg ML, 'Increased plasma fatty acid concentrations after respiratory exacerbations are associated with elevated oxidative stress in cystic fibrosis patients (vol 75, pg 668, 2002)', AMERICAN JOURNAL OF CLINICAL NUTRITION, 76 907-907 (2002)
Co-authors Lisa Wood, Peter Gibson
2002 Wood LG, Fitzgerald DA, Gibson PG, Cooper DM, Garg ML, 'Increased plasma fatty acid concentrations after respiratory exacerbations are associated with elevated oxidative stress in cystic fibrosis patients', American Journal of Clinical Nutrition: a journal reporting the practical application of our world-wide knowledge of nutrition, 75 668-675 (2002) [C1]
Citations Scopus - 39Web of Science - 33
Co-authors Peter Gibson, Lisa Wood
2001 Blake R, Garg M, Trim G, Leitch J, 'Incorporation of n-3 polyunsaturated fatty acids into atrial myocardium following supplementation with fish oil', CIRCULATION, 104 744-744 (2001)
2001 Harrison RA, Harrison BJ, Volker D, Garg M, 'Fish oils are beneficial to patients with established rheumatoid arthritis [4]', Journal of Rheumatology, 28 2563-2565 (2001)
Citations Scopus - 3
2001 Volker D, Garg ML, 'Fish oils are beneficial to patients with established rheumatoid arthritis - Reply', Journal of Rheumatology, 28 2564-2565 (2001) [C3]
2001 Wood L, Fitzgerald D, Gibson PG, Cooper D, Collins C, Garg M, 'Oxidative Stress in Cystic Fibrosis: Dietary and Metabolic Factors', Journal of the American College of Nutrition, 20 157-165 (2001) [C1]
Citations Scopus - 67Web of Science - 55
Co-authors Clare Collins, Lisa Wood, Peter Gibson
2001 Nair S, Leitch J, Garg ML, 'N-3 polyunsaturated fatty acid supplementation alters inositol phosphate metabolism and protein kinase C activity in adult porcine cardiac myocytes', Journal of Nutritional Biochemistry, 12 7-13 (2001) [C1]
Citations Scopus - 18Web of Science - 17
2001 Read M, Leitch J, Garg ML, Osmond D, Falconer J, 'Dietary n-3 Fatty Acids Alter the Contractile Response to Thromboxane A2 Agonists of Porcine Coronary Arteries', Journal of Nutritional Biochemistry, 12 258-265 (2001) [C1]
Citations Scopus - 1Web of Science - 1
2000 Volker DH, Fitzgerald P, Garg ML, 'The eicosapentaenoic to docosahexaenoic acid ratio of diets affects the pathogenesis of arthritis in Lew/SSN rats', Journal of Nutrition, 130 559-565 (2000) [C1]
Citations Scopus - 51Web of Science - 46
2000 Volker DH, Bates M, Gentle R, Garg ML, 'Oral buprenorphine is anti-inflammatory and modulates the pathogenesis of streptococcal cell wall polymer induced arthritis in the Lew/SSN rat', Laboratory Animals, 34 423-429 (2000) [C1]
Citations Scopus - 13Web of Science - 10
2000 Wood LG, Fitzgerald DA, Gibson PG, Cooper DM, Garg ML, 'Lipid Peroxidation as Determined by Plasma Isoprostanes Is Related to Disease Severity in Mild Asthma', Lipids, 35;9 967-974 (2000) [C1]
Citations Scopus - 120Web of Science - 108
Co-authors Lisa Wood, Peter Gibson
2000 Quaggiotto P, Leitch J, Falconer J, Murdoch R, Garg ML, 'Plasma F2a-isoprostane levels are lowered in pigs fed an n-3 polyunsaturated fatty acid supplemented diet following occlusion of the left anterior descending coronary artery', Nutrition Research, 20 675-684 (2000) [C1]
Citations Scopus - 9Web of Science - 8
2000 Nair S, Leitch JW, Garg M, 'SUPPRESSION OF INOSITOL PHOSPHATE RELEASE BY CARDIAC MYOCYTES ISOLATED FROM FISH OIL-FED PIGS', MOLECULAR AND CELLULAR BIOCHEMISTRY, 215 57-64 (2000) [C1]
Citations Scopus - 12Web of Science - 11
2000 Nair S, Leitch J, Garg ML, 'Suppression of inositol phosphate release in dietary n-3 polyunsaturated fatty acid modified porcine cardiomyocytes', Molecular and Cellular Biochemistry, 215 57-64 (2000) [C1]
2000 Volker D, Fitzgerald P, Major GA, Garg M, 'Efficacy of Fish Oil Concentrate in the Treatment of Rheumatoid Arthritis', Journal of Rheumatology, 27 2343-2346 (2000) [C1]
Citations Scopus - 122Web of Science - 101
1999 Nair S, Leitch J, Falconer J, Garg ML, 'Cardiac n-3 non-esterified fatty acids are selectively increased in fish oil fed pigs following myocardial ischemia', Journal of Nutrition, 129 1518-1523 (1999) [C1]
Citations Scopus - 26Web of Science - 25
1999 Nair S, Leitch J, Garg ML, 'Selective incorporation of n-3 PUFA into phosphatidyl inositol and NEFA fractions of cultured porcine myocytes', LIPIDS, 34 697-704 (1999) [C1]
1999 Collins CE, Quaggiotto P, O'Loughlin E, Henry R, Garg ML, 'Elevated plasma levels of F2a-isoprostane in cystic fibrosis', LIPIDS, 34 551-556 (1999) [C1]
Citations Scopus - 74Web of Science - 63
Co-authors Lisa Wood, Clare Collins
1999 Nair SSD, Leitch J, Garg ML, 'Specific modifications of phosphatidylinositol and nonesterified fatty acid fractions in cultured porcine cardiomyocytes supplemented with n-3 polyunsaturated fatty acids', LIPIDS, 34 697-704 (1999)
DOI 10.1007/s11745-999-0415-3
Citations Scopus - 7Web of Science - 9
1999 Fitzgerald DA, Wood LG, Cooper DM, Gibson PG, Garg ML, 'Isoprostanes and antioxidant defences in cystic fibrosis', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 159 A682-A682 (1999)
Co-authors Peter Gibson, Lisa Wood
1998 Volker DH, Major G, Garg ML, 'Fat, n-6 and n-3 fatty acid intake in rheumatoid arthritis and osteoarthritis patients', Australian Journal of Nutrition and Dietetics, 55 69-73 (1998) [C1]
1998 Garg ML, Blake RJ, Jansen M, 'Fecal Sterol Excretion in Rats Fed Diets Enriched in Linoleic, alpha-Linolenic, and Eicosapentaenoic Plus Docosahexaenoic Acid', Journal of Clinical Biochemistry and Nutrition, 24 23-34 (1998) [C1]
Citations Scopus - 1Web of Science - 1
1997 May GL, Wright LC, Obbink KG, Byleveld PM, Garg ML, Ahmad ZI, Sorrell TC, 'Increased saturated triacylglycerol levels in plasma membranes of human neutrophils stimulated by lipopolysaccharide', JOURNAL OF LIPID RESEARCH, 38 1562-1570 (1997)
Citations Scopus - 14Web of Science - 13
1997 Nair SSD, Leitch JW, Falconer J, Garg ML, 'Prevention of cardiac arrhythmia by dietary (n-3) polyunsaturated fatty acids and their mechanism of action', JOURNAL OF NUTRITION, 127 383-393 (1997)
Citations Scopus - 177Web of Science - 152
1997 Garg M, Blake R, Reinhard B, 'Comparative effects of dietary fat manipulation on fatty acid composition of rat stomach, jejunum, and colon phospholipids', JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 22 101-111 (1997)
Citations Scopus - 2Web of Science - 2
1996 Pick ME, Hawrysh ZJ, Gee MI, Toth E, Garg ML, Hardin RT, 'Oat bran concentrate bread products improve long-term control of diabetes: A pilot study', JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION, 96 1254-1261 (1996)
DOI 10.1016/S0002-8223(96)00329-X
Citations Scopus - 104Web of Science - 88
1996 Volker D, Garg M, 'Dietary N-3 fatty acid supplementation in rheumatoid arthritis - Mechanisms, clinical outcomes, controversies, and future directions', JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 20 83-97 (1996)
Citations Scopus - 27Web of Science - 27
1994 Thomson ABR, Garg M, Keelan M, Doring K, 'Feeding trans fatty acids to rats has no effect on the intestinal uptake of glucose, fatty acids or cholesterol', Digestion, 55 405-409 (1994)

Trans fatty acids are produced in the manufacture of margarine, and these hydrogenated fatty acids may have a deleterious effect on the reduction in fasting levels of serum choles... [more]

Trans fatty acids are produced in the manufacture of margarine, and these hydrogenated fatty acids may have a deleterious effect on the reduction in fasting levels of serum cholesterol anticipated from the feeding of cis polyunsaturated fatty acids. We undertook this study in rats to test the effect of feeding trans fatty acids on the intestinal uptake of glucose, fatty acids and cholesterol. Adult female Wistar rats were fed for 2 weeks semisynthetic, isocaloric diets containing no oleic acid (18:1), cis 18:1 or trans 18:1. There was no difference between the three dietary groups in the animals' food consumption or body weight gain. Rats fed trans 18:1 had an approximately 20% decline in the total weight of the ileum as compared with controls fed no 18:1, and therefore there was also a decline in the percentage of the ileal tissue comprised of mucosa. When comparing rats fed trans 18:1 with those fed cis 18:1 or no 18:1, there was no difference in the uptake of varying concentrations of D-glucose when expressed as nmol.100 mg tissue -1 .min -1 or nmol.100 mg mucosa -1 .min -1 for jejunum or for ileum. Also, there was no difference in the value of the maximal transport rate (V(max)), Michaelis constant (K(m)), or the contribution of passive uptake of glucose assessed with L-glucose. There was no diet-associated change in the jejunal or ileal uptake of a medium-chain length fatty acid (lauric acid), a long-chain length saturated fatty acid (palmitic acid), a monounsaturated fatty acid (oleic acid), two polyunsaturated fatty acids (linoleic and linolenic acids), or cholesterol. Thus, we conclude that 2 weeks' feeding of trans fatty acid to rats has no influence on the jejunal or ileal uptake of glucose, fatty acids or cholesterol.

Citations Scopus - 2
1994 Keelan M, Thomson AB, Garg ML, Wierzbicki E, Wierzbicki AA, Clandinin MT, 'Dietary omega-3 fatty acids and cholesterol modify desaturase activities and fatty acyl constituents of rat intestinal brush border and microsomal membranes of diabetic rats.', Diabetes Research, 26 47-66 (1994)

The diabetes-associated changes in intestinal uptake of nutrients are modified by isocaloric alterations in the type of dietary lipids, and is associated with alterations in the p... [more]

The diabetes-associated changes in intestinal uptake of nutrients are modified by isocaloric alterations in the type of dietary lipids, and is associated with alterations in the phospholipid and fatty acyl content of the intestinal brush border membrane. We wished to test the hypothesis that diet- and diabetes-associated changes in brush border membrane phospholipid fatty acids are due to alterations in the activity of enterocyte microsomal delta-5, delta-6 and delta-9 desaturases. Adult female Wistar rats were divided into two groups. In half of the animals, diabetes was produced with the injection of streptozotocin, and the other half of the animals served as nondiabetic controls. Both groups were raised on chow for two weeks and were then randomized to one of four semisynthetic diets for two weeks: beef tallow low in cholesterol (BT), beef tallow high in cholesterol (BTC), fish oil low in cholesterol (FO), or fish oil high in cholesterol (FOC). Feeding a high cholesterol diet increased the activity of jejunal enterocyte microsomal membrane activity of delta-5 and delta-9-desaturases when fed with FO in non-diabetic control rats, increased delta-5-desaturase in diabetic rats fed FO, and increased the ileal activity of delta-5 and delta-6-desaturases in control and diabetic animals fed FO. Dietary fatty acids, cholesterol and diabetes did not produce the changes in the amount of fatty acids in BBM phosphatidylcholine or phosphatidylethanolamine expected from the measured alterations in delta-5 (20:4 omega 6 and 20:5 omega 3), in delta-6 (18:3 omega 6 and 18:4 omega 3), or in delta-9 desaturase (18:1 omega 9 and 16:1 omega 7). In summary, 1) the activities of enterocyte microsomal membrane delta-5, delta-6 and delta-9-desaturases are independently influenced by dietary fatty acids or cholesterol, or by diabetes; 2) changes in dietary fatty acids, cholesterol and diabetes are associated with alterations in the fatty acyl constituents of brush border membrane phosphatidylcholine and phosphatidylethanolamine, but these fatty acyl changes are not explained on the basis of variations in the activities of the microsomal desaturases. Thus, the intestinal brush border membrane and the enterocyte microsomal desaturases are capable of adapting in response to changes in dietary lipids or diabetes, but the two alterations are not necessarily causally interrelated.

Citations Scopus - 7
1994 GARG ML, LI T, 'THE IMPORTANCE OF DIETARY EICOSAPENTAENOIC TO DOCOSAHEXAENOIC ACID RATIO IN MODULATION OF SERUM-LIPID AND ARACHIDONIC-ACID LEVELS', NUTRITION RESEARCH, 14 1575-1582 (1994)
DOI 10.1016/S0271-5317(05)80235-0
Citations Scopus - 16Web of Science - 17
1993 Thomson AB, Keelan M, Lam T, Rajotte RV, Garg ML, Clandinin MT, 'Fish oil modifies effect of high cholesterol diet on intestinal absorption in diabetic rats.', Diabetes Research, 22 171-183 (1993)

Omega-3 fatty acids (&apos;fish oil&apos;) reduce the intestinal absorption of glucose and lipids in normal and in diabetic rats, but their effect is altered by the presence of sa... [more]

Omega-3 fatty acids ('fish oil') reduce the intestinal absorption of glucose and lipids in normal and in diabetic rats, but their effect is altered by the presence of saturated or poly-unsaturated omega-6 fatty acids in the diet. This study was undertaken to test the hypothesis that the influence of fish oil on the intestinal uptake of nutrients in diabetic rats is also influenced by the cholesterol content of the diet. Streptozotocin diabetic rats were raised for 2 wk on semisynthetic diets in which the lipid composition was derived mainly from beef tallow (BT), beef tallow plus cholesterol (BTC), fish oil (FO), or fish oil plus cholesterol (FOC). Food intake and weight gain was similar in the 4 diet groups, although the fasting blood glucose was lowest in diabetic rats fed BT. Cholesterol supplementation increased intestinal wall and mucosal weights when fed with BT, but the opposite effect was seen with FO, with lower wall and mucosal mass with FOC than with FO. Ileal uptake of D-glucose was lower in FO than in BT or FOC. Cholesterol feeding was associated with enhanced jejunal uptake of cholesterol when fed with BT, but the converse was observed with FO. Thus, 1) the reduction of glucose absorption associated with feeding fish oil is blunted in the presence of a supplemented intake of cholesterol; and 2) a fish oil diet reduces cholesterol uptake even in the presence of a high level of dietary cholesterol. It remains to be established what is the optimal ratio of dietary saturated, polyunsaturated omega-3 and omega-6 fatty acids, and cholesterol required to normalize intestinal transport function in diabetic rats.

Citations Scopus - 2
1993 Basu TK, Ooraikul B, Garg M, 'The lipid-lowering effects of rhubarb stalk fiber: A new source of dietary fiber', Nutrition Research, 13 1017-1024 (1993)

Dried and ground rhubarb stalk fiber containing, on a dry weight basis, 74% total dietary fiber (66% insoluble and 8% soluble) was prepared from rhubarb plants grown in the provin... [more]

Dried and ground rhubarb stalk fiber containing, on a dry weight basis, 74% total dietary fiber (66% insoluble and 8% soluble) was prepared from rhubarb plants grown in the province of Alberta, Canada. Effect of this fiber source on the plasma and liver concentrations of cholesterol and triglycerides as well as the hepatic microsomal activities of ß-hydroxy ß-methyl coenzyme A reductase (HMGR) and acyl CoA: cholesterol acyl transferase (ACAT) were examined in mice receiving ad libitum a semi-synthetic diet containing 0.5% cholesterol. Feeding the cholesterol-enriched diet for 4 weeks in the presence of 5% rhubarb stalk fiber resulted in significantly lower plasma concentrations of cholesterol and triglycerides as well as hepatic concentrations of total cholesterol than those of animals receiving the diet where rhubarb fiber was substituted by 5% cellulose fiber. Dietary cholesterol supplementation accelerated ACAT activity. In the presence of 5% rhubarb fiber in the diet, this activity was restored to the level found in animals fed a cholesterol-free diet. On the other hand HMGR activity was inhibited by cholesterol supplementation and remained unaffected by addition of rhubarb fiber. These results indicate that rhubarb stalk fiber has a lipid-lowering effect which may not be mediated via alterations in the synthesis and metabolism of cholesterol. © 1993 Pergamon Press Ltd. All rights reserved.

DOI 10.1016/S0271-5317(05)80521-4
Citations Scopus - 9
1993 GARG ML, HAERDI JC, 'THE BIOSYNTHESIS AND FUNCTIONS OF PLASMALOGENS', JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 14 71-82 (1993)
Citations Web of Science - 9
1993 GUPTA S, THOMSON ABR, KAPPAGODA T, GARG ML, 'DIETARY CHOLESTEROL-INDUCED HYPERLIPIDEMIA MODULATES LIPID-SYNTHESIS IN RABBIT MONOCYTES', JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 15 11-21 (1993)
Citations Web of Science - 1
1993 BASU TK, OORAIKUL B, GARG ML, 'EFFECTS OF DIETARY PECTIN ON THE HEPATIC ACTIVITIES OF HYDROXYMETHYL GLUTARYL COA REDUCTASE AND ACYL COA CHOLESTEROL ACYLTRANSFERASE IN CHOLESTEROL SUPPLEMENTED MICE', JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 4 472-475 (1993)
DOI 10.1016/0955-2863(93)90065-5
Citations Scopus - 2Web of Science - 1
1992 GARG ML, KEELAN M, THOMSON ABR, CLANDININ MT, 'DESATURATION OF LINOLEIC-ACID IN THE SMALL-BOWEL IS INCREASED BY SHORT-TERM FASTING AND BY DIETARY CONTENT OF LINOLEIC-ACID', BIOCHIMICA ET BIOPHYSICA ACTA, 1126 17-25 (1992)
DOI 10.1016/0005-2760(92)90211-D
Citations Scopus - 39Web of Science - 44
1992 KANG JX, MAN SFP, BROWN NE, LABRECQUE PA, GARG ML, CLANDININ MT, 'ESSENTIAL FATTY-ACID METABOLISM IN CULTURED HUMAN AIRWAY EPITHELIAL-CELLS', BIOCHIMICA ET BIOPHYSICA ACTA, 1128 267-274 (1992)
DOI 10.1016/0005-2760(92)90317-O
Citations Scopus - 13Web of Science - 15
1992 GARG ML, 'STEARIC-ACID DESATURATION AND INCORPORATION INTO MURINE PERITONEAL MACROPHAGE LIPIDS', JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 13 169-178 (1992)
Citations Scopus - 4Web of Science - 4
1991 EMPEY LR, JEWELL LD, GARG ML, THOMSON ABR, CLANDININ MT, FEDORAK RN, 'FISH OIL-ENRICHED DIET IS MUCOSAL PROTECTIVE AGAINST ACETIC ACID-INDUCED COLITIS IN RATS', CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 69 480-487 (1991)
Citations Scopus - 42Web of Science - 39
1991 CLANDININ MT, CHEEMA S, FIELD CJ, GARG ML, VENKATRAMAN J, CLANDININ TR, 'DIETARY-FAT - EXOGENOUS DETERMINATION OF MEMBRANE-STRUCTURE AND CELL-FUNCTION', FASEB JOURNAL, 5 2761-2769 (1991)
Citations Scopus - 217Web of Science - 224
1990 Thomson AB, Keelan M, Sigalet D, Fedorak R, Garg M, Clandinin MT, 'Patterns, mechanisms and signals for intestinal adaptation.', Digestive Diseases, 8 99-111 (1990)
Citations Scopus - 10
1990 GARG ML, THOMSON ABR, CLANDININ MT, 'INTERACTIONS OF SATURATED, N-6 AND N-3 POLYUNSATURATED FATTY-ACIDS TO MODULATE ARACHIDONIC-ACID METABOLISM', JOURNAL OF LIPID RESEARCH, 31 271-277 (1990)
Citations Scopus - 105Web of Science - 120
1990 SEBOKOVA E, GARG ML, WIERZBICKI A, THOMSON ABR, CLANDININ MT, 'ALTERATION OF THE LIPID-COMPOSITION OF RAT TESTICULAR PLASMA-MEMBRANES BY DIETARY (N-3) FATTY-ACIDS CHANGES THE RESPONSIVENESS OF LEYDIG-CELLS AND TESTOSTERONE SYNTHESIS', JOURNAL OF NUTRITION, 120 610-618 (1990)
Citations Scopus - 33Web of Science - 31
1989 Thomson ABR, Keelan M, Garg M, Clandinin MT, 'Evidence for critical-period programming of intestinal transport function: variations in the dietary ratio of polyunsaturated to saturated fatty acids alters ontogeny of the rat intestine', Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, 1001 302-315 (1989)

2-week isocaloric modifications in the dietary ratio of polyunsaturated/saturated fatty acids (P/S) alters intestinal transport in rats. This study was undertaken to test the hypo... [more]

2-week isocaloric modifications in the dietary ratio of polyunsaturated/saturated fatty acids (P/S) alters intestinal transport in rats. This study was undertaken to test the hypotheses that (1) the fatty acid composition of a nutritionally adequate diet in early life has lasting consequences for active and passive intestinal transport processes; and (2) early life feeding experiences with diets of varying fatty acid composition influence the intestines' ability to adaptively up- or down-regulate intestinal transport in later life. Female Sprague-Dawley rats were weaned onto S or P and were maintained on these diets for 2, 10 or 12 weeks. An in vitro uptake technique was used in which the bulk phase was vigorously stirred to reduce the effective resistance of the intestinal unstirred water layer. P decreased and S increased the uptake of glucose, and this effect was progressive from 2 to 12 weeks. Switching from a P to an S diet decreased jejunal but increased ileal uptake of glucose, whereas switching from an S to a P diet was associated with a decline in both the jejunal and the ileal uptake of glucose. The ileal uptake of galactose increased as the animals grew on either P or S. Switching from P to S resulted in a decline in ileal uptake of galactose, whereas the opposite effect was observed when switching from S to P. The effect of feeding P or S on hexose uptake was influenced by the animals' dietary history: ileal glucose and galactose uptake was lower in animals fed P at an early age (PSP) than in animals fed P for the first time in later life (SSP). Jejunal glucose and galactose uptake was also lower in animals fed S at an early age (SPS) than in those fed S for the first time in later life (PPS). The alterations in the uptake of long-chain saturated and unsaturated fatty acids and cholesterol did not progress with longer periods of feeding, and in the jejunum, lipid uptake did not change when switching from P to S or S to P. Early feeding with P (PSP vs. SSP) was associated with lower jejunal uptake of 18:3 and lower ileal uptake of 12:0, whereas previous feeding with S (SPS vs. PPS) was associated with lower ileal uptake of cholesterol. The changes in uptake of hexoses and lipids was not explained by differences in the animals' food consumption, body or intestinal weight or mucosal surface area. Thus, (1) the effect of changes in the dietary P/S ratio on hexose uptake are fast, progressive and irreversible, whereas the general effect on lipid uptake is nonprogressive and irreversible; and (2) the intestinal uptake of hexoses and some lipids is subject to critical-period programming. This late effect of early nutrition signifies that the adaptability of intestinal transport is subject to dietary variations shortly after weaning. © 1989.

DOI 10.1016/0005-2760(89)90115-X
Citations Scopus - 25
1989 Thomson ABR, Keelan M, Garg ML, Clandinin MT, 'Intestinal aspects of lipid absorption: in review', Canadian Journal of Physiology and Pharmacology, 67 179-191 (1989)

The rapidly evolving field of absorption is reviewed with the thrust of new knowledge focused on the interpendency of the luminal and cellular phases of absorption. To date little... [more]

The rapidly evolving field of absorption is reviewed with the thrust of new knowledge focused on the interpendency of the luminal and cellular phases of absorption. To date little attention has been paid to factors that regulate the phospholipid biosynthesis in the enterocyte. The availability of 20:4¿6 may be the rate-limiting factor for phospholipid synthesis. The source of 20:4¿6 is unknown, whether it be synthesized de novo the enterocyte or entirely originating from degradation of bile phospholipid. It has been established that dietary fat can modulate the enterocyte membrane lipid composition and transport properties. Specified fats such as as fish oils rich in 20:5¿3 and 22:6¿3 have been implicated as protective against hypercholesterolemia. However, the effects of these dietary fats on the transport of nutrients across the enterocyte are not yet known, nor are the mechanisms responsible for the adaptive responses of the brush border identified.

Citations Scopus - 95
1989 Garg ML, Wierzbicki AA, Thomson ABR, Clandinin MT, '¿-3 fatty acids increase the arachidonic acid content of liver cholesterol ester and plasma triacylglycerol fractions in the rat', Biochemical Journal, 261 11-15 (1989)

Recent studies have demonstrated that dietary fish oils rich in eicosapentaenoic acid (C(20:5,¿3)) lower the content of arachidonic acid and its metabolites in plasma and tissue ... [more]

Recent studies have demonstrated that dietary fish oils rich in eicosapentaenoic acid (C(20:5,¿3)) lower the content of arachidonic acid and its metabolites in plasma and tissue phospholipids. The persent study examined the fatty acid composition of cholesterol ester and triacylglycerol fractions from plasma and livers of rats fed diets enriched with saturated fatty acids (beef tallow), a-linolenic acid (linseed oil) or eicosapentaenoic acid (fish oil). Feeding diets containing linseed oil or fish oil for 28 days increased arachidonic acid (C(20:4,¿6)) levels in the cholesterol ester fraction of liver and in the triacylglycerol fraction of the plasma lipids. Plasma cholesterol esters were depleted of C(20:4,¿6) after feeding of the diet containing either linseed oil or fish oil. The changes in C(20:4,¿6) content cannot be explained by alterations in cholesterol ester or triacylglycerol pools of plasma and liver. These results suggest that the decrease in phospholipid C(20:4,¿6) content generally observed after fish oil consumption may be partly due to a shift of C(20:4,¿6) from phospholipid to the triacylglycerol and/or cholesterol ester pools in the same tissue. Triacylglycerols and cholesterol esters may therefore play a buffering role in the homoeostatic maintenance of tissue phospholipid levels of arachidonic acid.

Citations Scopus - 19
1989 Keelan M, Thomson ABR, Clandinin MT, Singh B, Rajotte R, Garg M, 'Improved intestinal form and function in diabetic rats fed long-term with a polyunsaturated fatty acid diet', Diabetes Research, 10 43-47 (1989)

Short-term (two weeks) feeding of isocaloric diets supplemented with polyunsaturated fatty acids (PUFA) is useful for the prevention or treatment of the enhanced uptake of glucose... [more]

Short-term (two weeks) feeding of isocaloric diets supplemented with polyunsaturated fatty acids (PUFA) is useful for the prevention or treatment of the enhanced uptake of glucose which occurs in rats with streptozotocin-induced diabetes, as compared with animals fed a diet supplemented with saturated fatty acids (SFA). The study was undertaken to compare the effects of long-term (seven weeks) feeding PUFA or SFA to diabetic rats. We have previously reported that diabetic animals fed PUFA had superior body weight gain, lower hemoglobin A1C values, lower plasma cholesterol and triglyceride levels, lower percentage decline in glucose (K value) following intravenous glucose tolerance testing, near-normal values of hepatic microsomal glucose-6-phosphatase activity and near-normal concentrations of 18:2(6) and 20:4(6) in liver microsomal phosphatidylcholine and phosphatidylserine. However, jejunal and ileal uptake of varying concentrations of glucose were similar in the three diet groups. Thus, the potential long-term beneficial effects of feeding diets with a high PUFA/SFA ratio probably have their explanation in metabolic effects distant to their uptake by the intestine.

Citations Scopus - 8
1989 GARG ML, THOMSON ABR, CLANDININ MT, 'HYPOTRIGLYCERIDEMIC EFFECT OF DIETARY N-3 FATTY-ACIDS IN RATS FED LOW VERSUS HIGH-LEVELS OF LINOLEIC-ACID', BIOCHIMICA ET BIOPHYSICA ACTA, 1006 127-130 (1989)
DOI 10.1016/0005-2760(89)90333-0
Citations Scopus - 9Web of Science - 15
1989 THOMSON ABR, KEELAN M, GARG ML, CLANDININ MT, 'FISH OIL PREVENTS EFFECT OF HIGH CHOLESTEROL DIET ON ACTIVE INTESTINAL TRANSPORT OF GALACTOSE', CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 67 829-836 (1989)
Citations Scopus - 3Web of Science - 3
1989 THOMSON ABR, KEELAN M, GARG ML, CLANDININ MT, 'INFLUENCE OF DIETARY-FAT COMPOSITION ON INTESTINAL-ABSORPTION IN THE RAT', LIPIDS, 24 494-501 (1989)
DOI 10.1007/BF02535128
Citations Scopus - 19Web of Science - 28
1989 GARG ML, WIERZBICKI A, KEELAN M, THOMSON ABR, CLANDININ MT, 'FISH OIL PREVENTS CHANGE IN ARACHIDONIC-ACID AND CHOLESTEROL CONTENT IN RAT CAUSED BY DIETARY-CHOLESTEROL', LIPIDS, 24 266-270 (1989)
DOI 10.1007/BF02535161
Citations Scopus - 18Web of Science - 23
1989 GARG ML, WIERZBICKI AA, THOMSON ABR, CLANDININ MT, 'DIETARY SATURATED FAT LEVEL ALTERS THE COMPETITION BETWEEN ALPHA-LINOLENIC AND LINOLEIC-ACID', LIPIDS, 24 334-339 (1989)
DOI 10.1007/BF02535173
Citations Scopus - 44Web of Science - 48
1989 GARG ML, WIERZBICKI AA, THOMSON ABR, CLANDININ MT, 'OMEGA-3 FATTY-ACIDS INCREASE THE ARACHIDONIC-ACID CONTENT OF LIVER CHOLESTEROL ESTER AND PLASMA TRIACYLGLYCEROL FRACTIONS IN THE RAT', BIOCHEMICAL JOURNAL, 261 11-15 (1989)
Citations Web of Science - 23
1988 SEBOKOVA E, GARG ML, CLANDININ MT, 'MODULATION OF RECEPTOR-MEDIATED GONADOTROPIN ACTION IN RAT TESTES BY DIETARY-FAT', AMERICAN JOURNAL OF PHYSIOLOGY, 254 E708-E712 (1988)
Citations Web of Science - 17
1988 GARG ML, KEELAN M, THOMSON ABR, CLANDININ MT, 'FATTY-ACID DESATURATION IN THE INTESTINAL-MUCOSA', BIOCHIMICA ET BIOPHYSICA ACTA, 958 139-141 (1988)
DOI 10.1016/0005-2760(88)90256-1
Citations Scopus - 39Web of Science - 51
1988 GARG ML, WIERZBICKI AA, THOMSON ABR, CLANDININ MT, 'DIETARY-CHOLESTEROL AND OR N-3 FATTY-ACID MODULATE DELTA-9-DESATURASE ACTIVITY IN RAT-LIVER MICROSOMES', BIOCHIMICA ET BIOPHYSICA ACTA, 962 330-336 (1988)
DOI 10.1016/0005-2760(88)90262-7
Citations Scopus - 53Web of Science - 53
1988 GARG ML, WIERZBICKI AA, THOMSON ABR, CLANDININ MT, 'FISH OIL REDUCES CHOLESTEROL AND ARACHIDONIC-ACID CONTENT MORE EFFICIENTLY IN RATS FED DIETS CONTAINING LOW LINOLEIC-ACID TO SATURATED FATTY-ACID RATIOS', BIOCHIMICA ET BIOPHYSICA ACTA, 962 337-344 (1988)
DOI 10.1016/0005-2760(88)90263-9
Citations Scopus - 32Web of Science - 40
1988 GARG ML, KEELAN M, WIERZBICKI A, THOMSON ABR, CLANDININ MT, 'REGIONAL DIFFERENCES IN LIPID-COMPOSITION AND INCORPORATION OF SATURATED AND UNSATURATED FATTY-ACIDS INTO MICROSOMAL-MEMBRANES OF RAT SMALL-INTESTINE', CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 66 794-800 (1988)
Citations Scopus - 21Web of Science - 25
1988 GARG ML, SEBOKOVA E, WIERZBICKI A, THOMSON ABR, CLANDININ MT, 'DIFFERENTIAL-EFFECTS OF DIETARY LINOLEIC AND ALPHA-LINOLENIC ACID ON LIPID-METABOLISM IN RAT-TISSUES', LIPIDS, 23 847-852 (1988)
DOI 10.1007/BF02536203
Citations Scopus - 78Web of Science - 90
1988 Sebokova E, Garg ML, Clandinin MT, 'Modulation of receptor-mediated gonadotropin action in rat testes by dietary fat', American Journal of Physiology - Endocrinology and Metabolism, 254 (1988)

The effect of feeding diets enriched with 18:2¿6, 18:2¿3, or saturated fatty acids on lipid composition and receptor-mediated action of lutinizing hormone/human chorionic gonado... [more]

The effect of feeding diets enriched with 18:2¿6, 18:2¿3, or saturated fatty acids on lipid composition and receptor-mediated action of lutinizing hormone/human chorionic gonadotropin (LH/hCG) in rat testicular plasma membranes was investigated. Linoleic and a-linoleic acid treatments reduced total phospholipid and cholesterol content of the testicular plasma membrane and altered membrane phospholipid composition. Change in phospholipid and cholesterol content after feeding the polyunsaturated fats decreased cholesterol to phospholipid ratios and binding capacity of the LH/hCG receptor in the testicular plasma membrane. LH-stimulated adenylate cyclase activity was decreased in animals fed the linolenic acid rich diet. NaF-stimulated adenylate cyclase activity was decreased in animals fed diets high in either polyunsaturated fatty acid. Decreased plasma membrane LH/hCG receptor content was associated with decreased testosterone production in Leydig cells in response to LH in the linolenic acid-fed group. It is suggested that change in cholesterol-to-phospholipid ratios alters the physical properties of testicular plasma membranes in a manner that influences accessibility of LH/hCG receptors in testicular tissue.

Citations Scopus - 11
1988 Thomson ABR, Keelan M, Garg M, Clandinin MT, 'Dietary effects of ¿3-fatty acids on intestinal transport function', Canadian Journal of Physiology and Pharmacology, 66 985-992 (1988)

Animals were fed for 2 weeks on one of four isocaloric and isocholesterolic semisynthetic diets: high 18:3¿3, low 18:3¿3, high 20:5¿3, or low 20:5¿3. The weight of the intesti... [more]

Animals were fed for 2 weeks on one of four isocaloric and isocholesterolic semisynthetic diets: high 18:3¿3, low 18:3¿3, high 20:5¿3, or low 20:5¿3. The weight of the intestine and the percentage of the wall consisting of mucosa was greater in high 20:5¿3 than in high 18:3¿3, and greater in low 20:5¿3 than in low 18:3¿3, although the mucosal surface area was 26% lower in high 20:5¿3 than high 18:3¿3. The jejunal uptake of 40 mM glucose and ileal uptake of 40 mM galactose was greater in high 18:3¿3 than in high 20:5¿3; jejunal uptake of fatty acid 12:0 was higher, but 18:0 was lower in high 18:3¿3 than in high 20:5¿3. The jejunal or ileal uptake of cholesterol was not affected by 20:5¿3. However, 20:5¿3 had a variable effect on the uptake of medium- and long-chain fatty acids. Alterations in the uptake of fatty acids and glucose were not explained by any difference in the animals' food consumption, body weight gain, or intestinal weight, but the reduced jejunal uptake of 40 mM glucose in rats fed the high 20:5¿3 diet was associated with reduced mucosal surface area. Thus, (i) varying the source of ¿3-fatty acids (vegetable, 18:3¿3 versus fish oil, 20:5¿3) altered the mucosal mass of the intestine, and (ii) the source of the dietary ¿3-fatty acid (18:3¿3 versus 20:5¿3) influenced intestinal hexose uptake, with fish oil having an anti-absorptive effect on the jejunal uptake of D-glucose.

Citations Scopus - 16
1988 Garg ML, Thomson ABR, Clandinin MT, 'Effect of dietary cholesterol and/or ¿3 fatty acids on lipid composition and ¿

Male weanling rats were fed for 28 d a purified diet containing 20% (wt/wt) fat providing high levels of either saturated fat or a-linolenic acid or eicosapentaenoic and docosahex... [more]

Male weanling rats were fed for 28 d a purified diet containing 20% (wt/wt) fat providing high levels of either saturated fat or a-linolenic acid or eicosapentaenoic and docosahexaenoic acids with or without 2% (wt/wt) cholesterol supplementation. Effect of diet on rate of desaturation of eicosatrienoic acid (20:3¿6) and lipid composition of liver microsomal membranes was examined. The desaturation of 20:3¿6 to arachidonic acid (20:4¿6) was higher in rats fed linseed oil and lower in rats fed fish oil than in control animals fed the beef tallow diet. The desaturation of 20:3¿6 was lower in rats fed beef tallow or linseed oil diets supplemented with cholesterol than in the respective unsupplemented diet. Inclusion of 2% (wt/wt) cholesterol in the fish oil diet failed to affect synthesis of 20:4¿6 from 20:3¿6. These in vitro changes in ¿ 5 -desaturase activity are consistent with the diet-induced alterations observed in the fatty acid composition of microsomal membranes. Both free cholesterol and cholesterol ester in the microsomal membrane were higher in rats fed beef tallow or linseed oil diets supplemented with exogenous cholesterol than in the respective unsupplemented diet, and only free cholesterol was higher in rats fed the fish oil diet supplemented with cholesterol. Feeding fish oil appears to prevent both the inhibition of 20:4¿6 biosynthesis and the accumulation of cholesterol ester that were apparent when 2% cholesterol was added to either beef tallow or linseed oil diets.

Citations Scopus - 98
1988 Garg ML, Sebokova E, Thomson ABR, Clandinin MT, '¿

The effect of feeding semipurified diets enriched in linseed (rich in C(18:3,¿3) fatty acid) or fish (rich in C(20:5,¿3) and C(22:6,¿3) fatty acid) oil with and without cholest... [more]

The effect of feeding semipurified diets enriched in linseed (rich in C(18:3,¿3) fatty acid) or fish (rich in C(20:5,¿3) and C(22:6,¿3) fatty acid) oil with and without cholesterol supplementation on the desaturation of linoleic acid (C(18:2,¿6) by rat liver microsomal fractions was investigated. Animals fed diets supplemented with beef tallow were used as equal-energy controls. Both linseed-oil and fish-oil diets, without added cholesterol, decrease conversion of C(18:2,¿6) fatty acid to ¿-linolenic acid (C(18:3,¿6)). Reduction in ¿ 6 -desaturation was significantly greater for animals fed the diet containing fish oil than with animals fed the linseed-oil diet. The major effect of cholesterol supplementation was to decrease the rate of desaturation of C(18:2,¿6), when fed in combination with the beef-tallow diet, whereas ¿ 6 -desaturation was unaffected when cholesterol was fed along with diets high in ¿3 fatty acids (linseed oil or fish oil). The activity of the ¿ 6 -desaturase in vitro is consistent with the fatty acid composition observed for the microsomal membranes on which this enzyme is localized dietary linseed oil and fish oil lowered the arachidonic (C(20:4,¿6)) acid content of rat liver microsomes, with an accompanying increase in membrane eicosapentaneoic (C(20:5,¿3)) and docosahexaneoic (C(22:6,¿3)) acid content, in comparison with the group fed beef tallow. Inclusion of cholesterol into the beef-tallow or linseed-oil diets resulted in decreased membrane C(20:4,¿6)-fatty-acid content, with concomitant increase in C(18:2,¿6)-fatty-acid content. However, addition of cholesterol to the fish-oil diet did not alter the microsomal membrane content of C(20:4,¿6) fatty acid. Thus it is suggested that (1) the decrease in prostaglandin E 2 , thromboxane and prostacyclin levels generally observed after fish-oil consumption may be at least partly due to inhibition of C(20:4,¿6)-fatty-acid synthesis from C(18:2,¿6) fatty acid; and (2) consumption of fish oil prevents the further decrease in C(20:4,¿6)-fatty-acid levels by dietary cholesterol that is apparent when cholesterol is fed in combination with diets high in saturated fat or C(18:3,¿3) fatty acid.

Citations Scopus - 210
1988 GARG ML, SEBOKOVA E, THOMSON ABR, CLANDININ MT, 'DELTA-6-DESATURASE ACTIVITY IN LIVER-MICROSOMES OF RATS FED DIETS ENRICHED WITH CHOLESTEROL AND OR OMEGA-3 FATTY-ACIDS', BIOCHEMICAL JOURNAL, 249 351-356 (1988)
Citations Web of Science - 231
1988 GARG ML, SABINE JR, 'HOMEOSTATIC CONTROL OF MEMBRANE CHOLESTEROL AND FATTY-ACID METABOLISM IN THE RAT-LIVER', BIOCHEMICAL JOURNAL, 251 11-16 (1988)
Citations Scopus - 15Web of Science - 15
1988 GARG ML, THOMSON ABR, CLANDININ MT, 'EFFECT OF DIETARY ALPHA-LINOLENIC ACID FED WITH HIGH-LEVELS OF EITHER SATURATED FATTY-ACIDS OR LINOLEIC-ACID ON CHOLESTEROL AND FATTY-ACID METABOLISM IN RAT SERUM AND LIVER', FASEB JOURNAL, 2 A852-A852 (1988)
1987 GARG ML, SEBOKOVA E, THOMSON ABR, CLANDININ MT, 'EFFECTS OF DIETARY (OMEGA-3) FATTY-ACIDS AND CHOLESTEROL ON DELTA-6-DESATURASE ACTIVITY IN RAT-LIVER MICROSOMES', JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 64 667-667 (1987)
1987 Thomson ABR, Keelan M, Garg M, Clandinin MT, 'Spectrum of effects of dietary long-chain fatty acids on rat intestinal glucose and lipid uptake', Canadian Journal of Physiology and Pharmacology, 65 2459-2465 (1987)

Isocaloric modification in the ratio of dietary polyunsaturated-to-saturated fatty acids influences intestinal uptake of actively and passively transported nutrients. This study w... [more]

Isocaloric modification in the ratio of dietary polyunsaturated-to-saturated fatty acids influences intestinal uptake of actively and passively transported nutrients. This study was undertaken to determine which dietary fatty acid was responsible for these alterations in absorption. Adult female rats were fed isocaloric semisynthetic diets high in palmitic and stearic acids (SFA), oleic acid (OA), linoleic acid (LA), or linolenic acid (LNA). An in vitro technique was used to measure the uptake of varying concentrations of glucose as well as a series of fatty acids and cholesterol. Jejunal uptake of 40 mM glucose was highest in rats fed SFA and lowest in those fed LA; ileal glucose uptake was similar in OA, LA, and LNA, but was lowest in SFA. Jejunal uptake of medium-chain fatty acids (8:0-12:0) was higher in OA than in other diet groups; ileal uptake of medium-chain fatty acids was unaffected by diet. Jejunal and ileal uptake of 18:2 was higher in LNA than in SFA or OA; the uptake of the other long-chain saturated or unsaturated fatty acids was unchanged by diet. The ileal but not the jejunal uptake of cholesterol was increased in LA as compared with SFA or OA, and reduced in LNA as compared with LA. These transport changes were not explained by differences in the animals' food consumption, body weight gain, intestinal mass, or mucosal surface area. We postulate that these diet-induced transport alterations may be mediated via changes in brush border membrane phospholipid fatty acyl composition. Thus, intestinal transport of nutrients may be varied by isocaloric changes in the dietary content of individual fatty acids.

Citations Scopus - 14
1986 GARG ML, SNOSWELL AM, SABINE JR, 'INFLUENCE OF DIETARY-CHOLESTEROL ON DESATURASE ENZYMES OF RAT-LIVER MICROSOMES', PROGRESS IN LIPID RESEARCH, 25 639-644 (1986)
DOI 10.1016/0163-7827(86)90131-1
Citations Scopus - 55Web of Science - 65
1985 GARG ML, SNOSWELL AM, SABINE JR, 'DIETARY-CHOLESTEROL MODIFIES BOTH CHOLESTEROL CONTENT AND FATTY-ACID PROFILES OF HEPATIC-MICROSOMAL MEMBRANES', NUTRITION REPORTS INTERNATIONAL, 32 17-26 (1985)
Citations Scopus - 6Web of Science - 14
1985 GARG ML, SNOSWELL AM, SABINE JR, 'EFFECT OF DIETARY-CHOLESTEROL ON CHOLESTEROL CONTENT AND FATTY-ACID PROFILES OF RAT-LIVER AND PLASMA', NUTRITION REPORTS INTERNATIONAL, 32 117-127 (1985)
Citations Scopus - 13Web of Science - 15
1985 GARG ML, SABINE JR, SNOSWELL AM, 'A COMPARISON OF THE INFLUENCE OF DIETS HIGH IN SATURATED VERSUS UNSATURATED FATTY-ACIDS ON LIPID-COMPOSITION AND GLUCOSE-6-PHOSPHATASE ACTIVITY OF RAT-LIVER MICROSOMES', BIOCHEMISTRY INTERNATIONAL, 10 585-595 (1985)
Citations Scopus - 17Web of Science - 21
1985 GARG ML, MCMURCHIE EJ, SABINE JR, 'MEMBRANE HOMEOSTASIS - THERMOTROPIC BEHAVIOR OF MICROSOMAL MEMBRANE-LIPIDS ISOLATED FROM LIVERS OF RATS FED CHOLESTEROL-SUPPLEMENTED DIETS', BIOCHEMISTRY INTERNATIONAL, 11 677-686 (1985)
Citations Scopus - 1Web of Science - 2
Show 221 more journal articles

Review (1 outputs)

Year Citation Altmetrics Link
2003 Wood LG, Gibson PG, Garg ML, 'Biomarkers of lipid peroxidation, airway inflammation and asthma', The European Respiratory Journal (2003) [D2]
Citations Scopus - 173Web of Science - 164
Co-authors Lisa Wood, Peter Gibson

Conference (203 outputs)

Year Citation Altmetrics Link
2017 Ferguson JJA, Stojanovski E, MacDonald-Wicks L, Garg ML, 'Lipid-Lowering Potential of Combined Phytosterols and Curcumin Supplementation in Hypercholesterolaemic Individuals', FASEB JOURNAL (2017)
Co-authors Elizabeth Stojanovski, Lesley Wicks
2017 Beckett EL, Martin C, King K, Niblett S, Ferguson J, Abbott K, et al., 'Omega-3 Index Predicts Cognitive Impairment Score in an MTHFR-C677T Dependent Manner', Omega-3 Index Predicts Cognitive Impairment Score in an MTHFR-C677T Dependent Manner (2017)
DOI 10.1159/000480052
Co-authors Emma Beckett, Mark Lucock, Katrina King, Martin Veysey
2016 Garg ML, Wood L, Dias C, 'Dietary Saturated Fat Promotes Omega-3 Polyunsaturated Fatty Acid Incorporation into Human Plasma and Erythrocytes', Eur J Clin Nutr. (2016)
Co-authors Lisa Wood
2016 Garg ML, Abbott K, Thota R, Acharya S, Burrows TL, 'Effect of Omega-3 Polyunsaturated Fatty Acids on Insulin Resistance are Sex-dependent: A Meta-analysis of Randomized Controlled Trials', FASEB JOURNAL (2016)
Co-authors Tracy Burrows
2015 Garg M, Abbott K, Veysey M, Lucock M, Niblett S, King K, Burrows T, 'Association Between Omega-3 Index and Type 2 Diabetes in Older Overweight/Obese People is Sex Dependent', FASEB JOURNAL (2015) [E3]
Co-authors Katrina King, Tracy Burrows, Mark Lucock, Martin Veysey
2015 Wong RHX, Jnasen L, Nealon R, Garg ML, Howe PRC, 'A PILOT INVESTIGATION OF CEREBROVASCULAR RESPONSIVENESS TO A NEUROPSYCHOLOGICAL TEST BATTERY IN ADULTS WITH TYPE 2 DIABETES MELLITUS', HYPERTENSION (2015) [E3]
Citations Web of Science - 1
Co-authors Rachel Wong, Peter Howe
2015 Fulton AS, Coates AM, Williams MT, Howe PRC, Frith PA, Wood LG, et al., 'Feasibility of a randomised controlled trial of fish oil supplementation in people with chronic obstructive pulmonary disease', Proceedings of the Nutrition Society of Australia (2015) [E3]
Co-authors Lisa Wood, Peter Howe
2015 Nealon R, Howe PRC, Jansen L, Garg ML, Wong RHX, 'Impaired cerebrovascular responsiveness to a working memory task in older adults with type 2 diabetes mellitus (T2DM)', Proceedings of the Nutrition Society of Australia (2015) [E3]
Co-authors Rachel Wong, Peter Howe
2015 Wong RHX, Nealon R, Jansen L, Garg M, Howe PRC, 'Cerebrovascular responsiveness to cognitive stimuli in adults with type 2 diabetes mellitus', Combined Abstracts of the 2015 Australian Psychology Conferences (2015) [E3]
Co-authors Peter Howe, Rachel Wong
2014 Song Y, Wang X-D, Smith N, Garg ML, Rose RJ, 'Seed oil storage in Medicago truncatula and Medicago orbicularis: the trade off between mucilage and oil production', ComBio2014 Online (2014) [E3]
Co-authors Ray Rose
2013 Scott HA, Gibson PG, Garg ML, Smart J, Wood LG, 'Female Reproductive Stage Drives The Association Between Obesity And Neutrophilic Airway Inflammation In Adults With Asthma', American Journal of Respiratory and Critical Care Medicine (2013) [E3]
Co-authors Lisa Wood, Hayley Scott, Peter Gibson
2013 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'The Association Between Obesity and Asthma is Driven By Female Reproductive Stage', Australasian Medical Journal (2013) [E3]
Co-authors Peter Gibson, Lisa Wood, Hayley Scott
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'High quality diet associated with a lower risk of type 2 diabetes', Proceedings of The Australian Diabetes Society (ADS) and Australian Diabetes Educators Association (ADEA) annual scientific meeting (2013) [E3]
Co-authors Mark Mcevoy, Elizabeth Stojanovski
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Australian diet quality scores as predictors of type 2 diabetes risk', Proceedings of The Nutrition Society of Australia and Nutrition Society of New Zealand Joint Annual Scientific Meeting (2013) [E3]
Co-authors Mark Mcevoy, Elizabeth Stojanovski
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Dietary fatty acid intake in relation to type 2 diabetes risk', Proceedings of the 2nd American Society For Nutrition (2013) [E3]
Co-authors Elizabeth Stojanovski, Mark Mcevoy
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Is macronutrient intake associated with development of type 2 diabetes?', Proceedings of the 2nd American Society For Nutrition Middle East Congress, Dubai, UAE, February 2013, Meeting (2013) [E3]
Co-authors Mark Mcevoy, Elizabeth Stojanovski
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Evaluation of macronutrient intake in relation to type 2 diabetes risk', Proceedings of the 7th International DIP Symposium on Diabetes, Hypertension, Metabolic Syndrome, and Pregnancy (2013) [E3]
Co-authors Elizabeth Stojanovski, Mark Mcevoy
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Association between whole blood omega-3 fatty acids and type 2 diabetes', Proceedings of the Australasian Section of the American Oil Chemists' Society Biannual meeting (2013) [E3]
Co-authors Mark Mcevoy, Elizabeth Stojanovski
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Whole blood fatty acid profile and incidence of type 2 diabetes in older Australians', Proceedings of the Nutrition Society of Australia and Nutrition Society of New Zealand Joint Annual Scientific Meeting (2013) [E3]
Co-authors Mark Mcevoy, Elizabeth Stojanovski
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Total carbohydrate intake does not predict type 2 diabetes risk in mid-age women', Proceedings of the The Australian Diabetes Society (ADS) and Australian Diabetes Educators Association (ADEA) annual scientific meeting (2013) [E3]
Co-authors Mark Mcevoy, Elizabeth Stojanovski
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'A prospective analysis of diet quality and type 2 diabetes risk', Proceedings of the World Diabetes Congress (2013) [E3]
Co-authors Mark Mcevoy, Elizabeth Stojanovski
2013 Scott HA, Gibson PG, Garg ML, Smart J, Wood LG, 'REPRODUCTIVE STAGE DRIVES LINK BETWEEN OBESITY AND NEUTROPHILIC AIRWAY INFLAMMATION IN FEMALES WITH ASTHMA', RESPIROLOGY (2013) [E3]
Co-authors Peter Gibson, Lisa Wood, Hayley Scott
2013 Dias C, Wood LG, Phang M, Garg ML, 'Omega-3 polyunsaturated fatty acids alleviate dietary saturated fat-induced postprandial rise in blood lipid levels', Nutrients (2013) [E3]
DOI 10.3390/nu5125065
Co-authors Lisa Wood
2012 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Female reproductive stage drives the association between obesity and neutrophilic airway inflammation in adults with asthma', Abstracts. American Thoracic Society 2012 International Conference (2012) [E3]
Co-authors Lisa Wood, Hayley Scott, Peter Gibson
2012 Garg ML, Singh H, 'Role of food matrix in lipid digestibility and adsorption', Abstracts. International Conference and Exhibition on Nutraceuticals and Functional Foods (2012) [E3]
2012 Phang M, Lincz L, Garg ML, 'Efficacy of EPA- and DHA- rich oils on platelet function in healthy men and women', Abstracts. International Conference and Exhibition on Nutraceuticals and Functional Foods (2012) [E3]
Co-authors Lisa Lincz
2012 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Reproductive stage drives link between obesity and neutrophilic airway inflammation in females with asthma', Abstracts. TSANZ Annual Scientific Meeting 2012 (2012) [E3]
Co-authors Hayley Scott, Peter Gibson, Lisa Wood
2012 Garg ML, 'Combined phytosterol and fish oil therapy for treatment for hyperlipidemia and improvement of cardiovascular health', Conference Handbook. Food Structures, Digestion and Health Conference (2012) [E3]
2012 Phang M, Lincz L, Garg ML, 'Eicosapentaenoic acid versus docosahexaenoic acid rich fish oils: Effect on platelet physiological response', Conference Handbook. Food Structures, Digestion and Health Conference (2012) [E3]
Co-authors Lisa Lincz
2012 Phang M, Lincz L, Garg ML, 'Omega-3 polyunsaturated fatty acids and platelet function: Sex dependence', Indian Journal of Hypertension (2012) [E3]
Co-authors Lisa Lincz
2012 Song Y, Sheahan MB, Liao SL, Wang X-D, Garg ML, Rose RJ, 'Comparative studies on medicago truncatula and medicago orbicualris: Towards regulatory control of seed storage partitioning', Poster abstracts. ComBio 2012 (2012) [E3]
Co-authors Ray Rose
2012 Song Y, Liao S, Wang X-D, Sheahan MB, Garg ML, Rose RJ, 'Investigation of gene expression underpinning partitioning of seed storage compunds in legumes', Proceedings of the 16th Agronomy Conference (2012) [E1]
Co-authors Ray Rose
2012 Phang M, Lincz L, Seldon MR, Garg ML, 'Differential effects of eicosapentaenoic and docosahexaenoic acids on platelet aggregation and hemostatic markers', Proceedings of the Nutrition Society of Australia (2012) [E3]
Co-authors Lisa Lincz
2012 Thomas J, Smith DW, Garg ML, 'Early molecular signature of neuro-protection in hippocampus of resveratrol diet fed C57BL/6 mice', Resveratrol 2012. 2nd International Conference of Resveratrol and Health (2012) [E3]
Co-authors Douglas Smith
2012 Addnan FH, Wood LG, Garg ML, Wark PA, 'Antiviral effects of antioxidants on human rhinovirus', Respirology (2012) [E3]
Co-authors Peter Wark, Lisa Wood
2012 Wood LG, Garg ML, Smart JM, Scott HA, Barker D, Gibson PG, 'Manipulating antioxidant intake in asthma: A randomized clinical trial', Respirology (2012) [E3]
Citations Web of Science - 2
Co-authors Lisa Wood, Hayley Scott, Peter Gibson
2012 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Weight loss improves clinical asthma outcomes and airway inflammation in overweight and obese asthmatics', Obesity Research & Clinical Practice (2012) [E3]
Co-authors Lisa Wood, Hayley Scott, Peter Gibson, Robin Callister, Philip Morgan
2011 Addnan FH, Wark PA, Wood LG, Garg ML, 'Antiviral activity of antioxidants against rhinovirus infection', Australasian Medical Journal (2011) [E3]
Co-authors Peter Wark, Lisa Wood
2011 Addnan FH, Wark PA, Wood LG, Garg ML, 'Effects of antioxidants on inflammation and apoptosis in rhinovirus-infected airway epithelial cells', Australasian Medical Journal (2011) [E3]
Co-authors Peter Wark, Lisa Wood
2011 Munro IA, Garg ML, 'Pre-supplementation with LCn-3PUFA for weight loss and improved blood biomarkers', Australasian Medical Journal (2011) [E3]
2011 Phang M, Lincz L, Garg ML, 'Gender specific effects of long-term dietary EPA and DHA supplementation in platelet aggregation in healthy human subjects', Australasian Medical Journal (2011) [E3]
Co-authors Lisa Lincz
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'The influence of body composition and inflammation on lung function in asthma', Australasian Medical Journal (2011) [E3]
Co-authors Peter Gibson, Philip Morgan, Robin Callister, Lisa Wood, Hayley Scott
2011 Thomas J, Smith DW, Garg ML, 'Dietary supplementation with resveratrol normalizes histone deacetylase (HDAC4) in the hippocampus of streptozotocin-induced diabetic mice', Australasian Medical Journal (2011) [E3]
Co-authors Douglas Smith
2011 Alhazmi AH, Stojanovski E, McEvoy MA, Garg ML, 'Omega-3 fatty acid intake and incidence of type 2 diabetes', Australasian Medical Journal (2011) [E3]
Co-authors Elizabeth Stojanovski, Mark Mcevoy
2011 Alhazmi AH, Stojanovski E, McEvoy MA, Garg ML, 'Association between dietary pattern and type 2 diabetes: A systematic literature review and meta-analysis', Australasian Medical Journal (2011) [E3]
Co-authors Mark Mcevoy, Elizabeth Stojanovski
2011 Song Y, Wang X-D, Garg ML, Sheahan MB, Rose RJ, 'Regulation of oil body biogenesis in the model legume medicago truncatula', COMBIO 2011: Annual Conferences of the Australian Society for Biochemistry and Molecular Biology, the Australian Society of Plant Scientists and the Australia and New Zealand Society for Cell and Deve (2011) [E3]
Co-authors Ray Rose
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Clinical asthma outcomes are improved after body fat reduction in overweight and obese asthmatics', American Journal of Respiratory and Critical Care Medicine (2011) [E3]
Co-authors Peter Gibson, Hayley Scott, Philip Morgan, Robin Callister, Lisa Wood
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Success in a weight loss trial is greatest in subjects with more severe asthma', American Journal of Respiratory and Critical Care Medicine (2011) [E3]
Co-authors Lisa Wood, Philip Morgan, Robin Callister, Hayley Scott, Peter Gibson
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Success in a weight loss trial is related to asthma severity', Respirology (2011) [E3]
Co-authors Robin Callister, Philip Morgan, Lisa Wood, Hayley Scott, Peter Gibson
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Body fat reduction improves clinical asthma outcomes in overweight and obese asthma', Respirology (2011) [E3]
Co-authors Lisa Wood, Robin Callister, Philip Morgan, Hayley Scott, Peter Gibson
2011 Kumar S, Sutherland F, Heck P, Teh A, Lee G, Medi C, et al., 'Mechanisms and effects of chronic omega-3 polyunsaturated fatty acid supplementation on human atrial electrical and mechanical function', Heart, Lung and Circulation (2011) [E3]
2011 Kumar S, Sutherland F, Teh A, Lee G, Heck P, Medi C, et al., 'Serum markers of omega-3 polyunsaturated fatty acid intake and electrophysiological vulnerability to atrial fibrillation', Heart, Lung and Circulation (2011) [E3]
2011 Kumar S, Teh A, Heck P, Sutherland F, Garg ML, Sparks P, 'Effects of chronic omega-3 polyunsaturated fatty acid supplementation on pulmonary vein and left atrial electrophysiology in patients with paroxysmal atrial fibrillation', Heart, Lung and Circulation (2011) [E3]
2011 Wood LG, Garg ML, Gibson PG, 'Dietary fat increases airway inflammation and attenuates bronchodilator response in asthma', XI Asian Congress of Nutrition 2011 (2011) [E3]
Co-authors Peter Gibson, Lisa Wood
2010 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Fatty acids and obesity differentially affect airway inflammation in males and females with asthma', American Journal of Respiratory and Critical Care Medicine (2010) [E3]
Co-authors Peter Gibson, Hayley Scott, Lisa Wood
2010 Wood LG, Garg ML, Wood A, Gibson PG, 'A high fat challenge enhances innate immune responses in asthmatic airways', American Journal of Respiratory and Critical Care Medicine (2010) [E3]
Co-authors Peter Gibson, Lisa Wood
2010 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Caloric restriction and exercise improve clinical asthma outcomes in overweight and obese asthma', Obesity Research & Clinical Practice (2010) [E3]
Co-authors Peter Gibson, Hayley Scott, Lisa Wood, Robin Callister, Philip Morgan
2010 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Caloric consumption and exercise improve clinical asthma outcomes in overweight and obese asthma', Obesity Research and Clinical Practice (2010) [E3]
Co-authors Robin Callister, Lisa Wood, Hayley Scott, Peter Gibson, Philip Morgan
2010 Garg ML, 'Scope of phytosterols and omega - 3 fatty acids in the management of hyperlipidemias', 15th World Congress on Clinical Nutrition (2010) [E3]
2010 Phang M, Lincz L, Garg ML, 'Gender specific role of n-3PUFA to inhibit microparticle activity in healthy humans', 15th World Congress on Clinical Nutrition (2010) [E3]
Co-authors Lisa Lincz
2010 Munro IA, Munro D, Bore MR, Garg ML, 'Personality as a prediciton of successful weight loss', 15th World Congress on Clinical Nutrition (2010) [E3]
Co-authors Miles Bore
2010 Phang M, Sinclair AJ, Lincz L, Garg ML, 'Omega-3 polyunsaturated fatty acis inhibit platelet-derived microparticle activiity in healthy human subjects', APSAVD 2010 Congress. AAS 2010 Annual Scientific Meeting. Abstract Book (2010) [E3]
Co-authors Lisa Lincz
2010 Lincz L, Scorgie F, Phang M, Garg ML, Enjeti A, Seldo M, 'Variability in platelet microparticle profile and aggregation in healthy males and females', Annual Scientific Meeting of the Haematology Society of Australia and New Zealand. Handbook and Program (2010) [E3]
Co-authors Lisa Lincz
2010 Munro IA, Garg ML, 'Gender: A determinant of weight loss through diet', Proceedings of the Nutrition Society of Australia (2010) [E3]
2010 Phang M, Lincz L, Sinclair AJ, Garg ML, 'Platelet-derived microparticle activity is inhibited by omega-3 fatty acid supplementation', Proceedings of the Nutrition Society of Australia (2010) [E3]
Co-authors Lisa Lincz
2010 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Clinical asthma outcomes are improved by caloric restriction and exercise in overweight and obese asthma', Proceedings of the Nutrition Society of Australia (2010) [E3]
Co-authors Lisa Wood, Hayley Scott, Philip Morgan, Robin Callister, Peter Gibson
2010 Thomas J, Smith DW, Garg ML, 'Dietary supplementation with resveratrol reduces erythrocyte arachidonic and docosahexaenoic acids levels in diabetic mice', Proceedings of the Nutrition Society of Australia (2010) [E3]
Co-authors Douglas Smith
2010 Munro IA, Bore MR, Munro D, Garg ML, 'Personality as a predictor of diet induced weight loss and weight management', Proceedings of the Nutrition Society of Australia, Volume 34 (2010) [E3]
Co-authors Miles Bore
2010 Wang X-D, Song Y, Garg ML, Rose RJ, 'From embryo sac to oil and protein bodies in the seed of the model legume Medicago truncatula', Vth International Congress on Legume Genetics and Genomics (2010) [E3]
Co-authors Ray Rose
2010 Song Y, Wang X-D, Garg ML, Rose RJ, 'From zygote to oil and protein bodies in the seed of the model legume Medicago Truncatula', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Abstracts (2010) [E3]
Co-authors Ray Rose
2010 Wood LG, Garg ML, Wood A, Gibson PG, 'Dietary fat enhances airway inflammation in asthma', Respirology (2010) [E3]
Co-authors Lisa Wood, Peter Gibson
2010 Burrows TL, Berthon B, Garg ML, Collins CE, 'A novel approach to validating dietary change in children participating in the HIKCUPS (Hunter Illawarra Kids Challenge Using Parent Support) obesity intervention', Obesity Reviews (2010) [E3]
Co-authors Tracy Burrows, Clare Collins
2009 Micallef MA, Garg ML, 'Phytosterols combined with oils rich in eicosapentaenoic or docosahexaenoic acid: A potential treatment for hyperlipidemia', World Congress on Oils and Fats & 28th ISF Congress: Program & Abstract Book (2009) [E3]
2009 Phang M, Garg ML, 'Redefining platelet aggregatory response to long chain omega-3 polyubsaturated fatty acids', World Congress on Oils and Fats & 28th ISF Congress: Program & Abstract Book (2009) [E3]
2009 Garg ML, Micallef MA, 'Nutraceuticals for reducing the risk of CVD in hyperlipidemic', 14th WCCN World Congress on Clinical Nutrition, 5th ICCD International Congress on Cardiovascular Diseases: Final Programe (2009) [E3]
2009 Munro IA, Garg ML, 'Weight loss and metabolic profiles in obese individuals using two different approaches', 14th WCCN World Congress on Clinical Nutrition, 5th ICCD International Congress on Cardiovascular Diseases: Final Programe (2009) [E3]
2009 Phang M, Garg ML, 'Inhibition of platelet aggregation by long chain omega-3 polyunsaturated fatty acid is gender specific', 14th WCCN World Congress on Clinical Nutrition, 5th ICCD International Congress on Cardiovascular Diseases: Final Programe (2009) [E3]
2009 Watson JF, Collins CE, Sibbritt DW, Garg ML, 'Parent versus child reporting using a food frequency questionnaire in Australia', 7th International Conference on Diet and Activity Methods (ICDAM7): Program and Abstracts (2009) [E3]
Co-authors Clare Collins
2009 Callister R, Plunkett BA, Garg ML, 'Effects of fish oil and lycopene supplements on cytokine responses to exercise', 9th Symposium of the International Society of Exercise and Immunology: Book of Abstracts (2009) [E3]
Co-authors Robin Callister
2009 Phang M, Sinclair AJ, Lincz L, Garg ML, 'Differential effects of dietary EPA or DHA supplementation on platelet aggregation in healthy male and female subjects', Atherosclerosis Society Annual Scientific Meeting 2009: Meeting Book (2009) [E3]
Co-authors Lisa Lincz
2009 Munro IA, Garg ML, 'The effect of two different weight loss approaches on anthropometric and metabolic profiles of obese individuals', Proceedings of the Nutrition Society of Australia (2009) [E3]
2009 Addnan FH, Wood LG, Garg ML, Wark PA, 'Resveratrol prevents hydrogen peroxide induced cytotoxicity', Proceedings of the Nutrition Society of Australia (2009) [E3]
Co-authors Peter Wark, Lisa Wood
2009 Phang M, Sinclair AJ, Lincz L, Garg ML, 'Differential effects of a single oral dose of EPA or DHA rich fish oil on platelet aggregation in health human subjects', Proceedings of the Nutrition Society of Australia (2009) [E3]
Co-authors Lisa Lincz
2009 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Plasma fatty acid profiles are different in obese versus non-obese asthma', Proceedings of the Nutrition Society of Australia (2009) [E3]
Co-authors Peter Gibson, Hayley Scott, Lisa Wood
2009 Scott HA, Gibson PG, Garg ML, Smart J, Wood LG, 'Neutrophilic Airway Inflammation Links Asthma and Obesity', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009) [E3]
Co-authors Hayley Scott, Peter Gibson, Lisa Wood
2009 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Asthma and obesity are linked via neutrophilic airway inflammation', Respirology (2009) [E3]
DOI 10.1111/j.1440-1843.2009.01503_1.x
Co-authors Peter Gibson, Hayley Scott, Lisa Wood
2009 Wood LG, Garg ML, Smith AJ, Smart JM, Gibson PG, 'A high fat, high energy food challenge induces an exaggerated inflammatory response in asthma', Respirology (2009) [E3]
DOI 10.1111/j.1440-1843.2009.01503_1.x
Co-authors Lisa Wood, Peter Gibson
2008 Hanstock T, Hirneth SJ, Kable CJ, Garg ML, Hazell P, Clayton EH, 'Omega-3 supplementation in juvenile bipolar disorder', Australian and New Zealand Journal of Psychiatry (2008) [E3]
Co-authors Tanya Hanstock
2008 Clayton EH, Hanstock T, Hirneth SJ, Kable CJ, Garg ML, Hazell P, 'Blood concentrations of omega-3 in participants with juvenile bipolar disorder compared to healthy controls', Australian and New Zealand Journal of Psychiatry (2008) [E3]
Co-authors Tanya Hanstock
2008 Wood LG, Garg ML, Smith AJ, Smart JM, Gibson PG, 'A high fat challenge activates the innate immune response in asthma', Asia Pacific Journal of Clinical Nutrition (2008) [E3]
Co-authors Lisa Wood, Peter Gibson
2008 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Obesity is associated with increased inflammation in asthma', Asia Pacific Journal of Clinical Nutrition (2008) [E3]
Co-authors Hayley Scott, Lisa Wood, Peter Gibson
2008 Phang M, Munro IA, Micallef MA, Garg ML, 'Gender differences in the relationship between plasma leptin and long chain omega-3 polyunsaturated fatty acids', Asia Pacific Journal of Clinical Nutrition (2008) [E3]
2008 Phang M, Micallef MA, Munro IA, Garg ML, 'Plasma n-3 polyunsaturated fatty acids and weight status in free living adults', Asia Pacific Journal of Clinical Nutrition (2008) [E3]
2008 Micallef MA, Munro IA, Garg ML, 'Relationship of obesity and abdominal adiposity with plasma C-reactive protein, interleukin-6 and omega-3 polyunsaturated fatty acids', Asia Pacific Journal of Clinical Nutrition (2008) [E3]
2008 Micallef MA, Garg ML, 'Anti-inflammatory and cardio-protective effects of omega-3 polyunsaturated fatty acids and plant sterols in hyperlipidemic individuals', Asia Pacific Journal of Clinical Nutrition (2008) [E3]
2008 Munro IA, Garg ML, 'Very low kilojoule diet (VLCD) assisted weight loss with or without dietary supplementation with n-3 polyunsaturated fatty acids', Asia Pacific Journal of Clinical Nutrition (2008) [E3]
2008 Clayton EH, Hanstock T, Hazell PL, Hirneth SJ, Kable CJ, Garg ML, 'Reduced erythrocyte concentration of omega-3 polyunsaturated fatty acids in children and adolescents with bipolar disorder', Asia Pacific Journal of Clinical Nutrition (2008) [E3]
Co-authors Tanya Hanstock
2008 Garg ML, 'Biomarkers for the assessment of antioxidant status', 13th World Congress on Clinical Nutrition: Congress Proceedings (2008) [E3]
2008 Garg ML, 'Long chain omega-3 fatty acid and recommendations and the food supply', 13th World Congress on Clinical Nutrition: Congress Proceedings (2008) [E3]
2008 Micallef MA, Garg ML, 'Combined phytosterol and omega-3 fatty acid supplementation in the management of hyperlipidemia: Effects on plasma lipids, inflammation and cardiovascular risk', 13th World Congress on Clinical Nutrition: Congress Proceedings (2008) [E3]
2008 Munro IA, Garg ML, 'Very low kilojoule diets and long chain polyunsaturated omega-3 fatty acids for weight loss in obese subjects', 13th World Congress on Clinical Nutrition: Congress Proceedings (2008) [E3]
2008 Phang M, Micallef MA, Munro IA, Garg ML, 'Plasma long chain omega-3 polyunsaturated fatty acids and obesity', Functional Foods 2008: Functional Foods & Edible Oils: The Future: Conference Proceedings (2008) [E3]
2008 Micallef MA, Garg ML, 'Anti-inflammatory and cardio-protective effects of omega-3 polyunsaturated fatty acids and plant sterols in hyperlipidemic individuals', Functional Foods 2008: Functional Foods & Edible Oils: The Future: Conference Proceedings (2008) [E3]
2008 Lazarus S, Micallef MA, Garg ML, 'Synergistic effects of tomato serum and long chain omega-3 fatty acids on platelet aggregation', Proceedings of 11th International Symposium on Traditional Medicine: In What Areas are Traditional/Alternative Medicines Useful? (2008) [E2]
2007 Hanstock T, Hazell P, Garg ML, Hirneth SJ, Morrison SDL, Kable CJ, Clayton EH, 'Omega-3 blood levels in children and adolescents with bipolar disorder', Bipolar Disorders (2007) [E3]
DOI 10.1111/j.1399-5618.2007.00542.x
Co-authors Tanya Hanstock
2007 Watson JF, Collins CE, Sibbritt DW, Garg ML, 'Can we be sure about differences in the dietary intakes of healthy weight and overweight/obese children?', ASSO 15th Annual Scientific Meeting 2007. Abstracts (2007) [E3]
Co-authors Clare Collins
2007 Garg ML, 'Long chain omega-3 fatty acids and the food supply', Asia Pacific Journal of Clinical Nutrition (2007) [E3]
2007 Micallef MA, Garg ML, 'Synergistic effects of phytosterols and long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) on cardiovascular risk reduction in hyperlipidemic subjects', Asia Pacific Journal of Clinical Nutrition (2007) [E3]
2007 Micallef MA, Garg ML, 'Lipid-lowering potential of combined phytosterols and long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) in hyperlipidemia', Asia Pacific Journal of Clinical Nutrition (2007) [E3]
2007 Munro IA, Smith CJ, Garg ML, 'The role of long chain polyunsaturated omega-3 fatty acids in weight maintenance', Asia Pacific Journal of Clinical Nutrition (2007) [E3]
2007 Munro IA, Smith CJ, Garg ML, 'Long chain polyunsaturated omega-3 fatty acids for weight loss in obese subjects', Asia Pacific Journal of Clinical Nutrition (2007) [E3]
2007 Plunkett BA, Watson TA, Callister R, Garg ML, 'Exercise, antioxidant restriction and the immune response in athletes', Asia Pacific Journal of Clinical Nutrition (2007) [E3]
Co-authors Robin Callister
2007 Saedi Some Olia A, Garg ML, Wood LG, Wark PA, Gibson PG, 'Lycopene enrichment of cultured epithelial airway cells', Asia Pacific Journal of Clinical Nutrition (2007) [E3]
Co-authors Peter Gibson, Peter Wark, Lisa Wood
2007 Shi Z, Hu X, He K, Yuan B, Garg ML, 'Joint association of magnesium and iron intake with anemia among Chinese adults', Asia Pacific Journal of Clinical Nutrition (2007) [E3]
2007 Micallef MA, Garg ML, 'Synergistic lipid-lowering effects of phytosterols and long chain omega-3 fatty acids (LCn-3PUFA) in hyperlipidemic subjects', Australian Atherosclerosis Society Annual Scientific Meeting 2007. Abstracts (2007) [E3]
2007 Saedi Some Olia A, Garg ML, Wood LG, Gibson PG, Wark PA, 'Anti-inflammatory effect of lycopene enrichment on infected cultured airway epithelial cells', Respirology (Abstracts of the 12th Congress of the Asian Pacific Society of Respirology) (2007) [E3]
Co-authors Lisa Wood, Peter Wark, Peter Gibson
2007 Wood LG, Garg ML, Powell H, Gibson PG, 'Dietary lycopene reduces neutrophilic airway inflammation in asthma', Respirology (TSANZ Abstracts-Posters) (2007) [E3]
Co-authors Lisa Wood, Peter Gibson
2007 Garg ML, 'Functional foods for heart health', XII World Congress on Clinical Nutrition. Program and Abstracts (2007) [E3]
2007 Micallef MA, Garg ML, 'Long chain omega-3 polyunsaturated fatty acids in the management of hyperlipidemia: A pilot study', XII World Congress on Clinical Nutrition. Program and Abstracts (2007) [E3]
2007 Plunkett BA, Watson TA, Callister R, Garg ML, 'Dietary antioxidant restriction affects the inflammatory response in male endurance athletes performing short-duration exhaustive exercise', XII World Congress on Clinical Nutrition. Program and Abstracts (2007) [E3]
Co-authors Robin Callister
2006 Wood LG, Garg ML, Gibson PG, 'Asthma control deteriorates on a low antioxidant diet', European Respiratory Journal Supplement (2006) [E3]
Co-authors Lisa Wood, Peter Gibson
2006 Marley AM, Sibberitt D, Garg ML, 'High protein or high carbohydrate diet for diabetes type 2: does it matter?', Asia Pacific Journal of Clinical Nutrition (2006) [E3]
2006 Kok WS, Munro IA, Garg ML, 'Knowledge and consumption of long chain n-3 polyunsaturated fatty acids (LCn-3PUFA) in young adult tertiary students', Asia Pacific Journal of Clinical Nutrition (2006) [E3]
2006 Clayton EH, Phang M, Garg ML, 'Determinants of platelet aggregation - implications for nutrition intervention trials', Asia Pacific Journal of Clinical Nutrition (2006) [E3]
2006 Plunkett BA, Callister R, Garg ML, 'The inflammatory response of acute maximal exercise in athletes', Asia Pacific Journal of Clinical Nutrition (2006) [E3]
Co-authors Robin Callister
2006 Plunkett BA, Watson TA, Callister R, Garg ML, 'Antioxidant restriction affects inflammatory response in short-duration exhaustive exercise', Asia Pacific Journal of Clinical Nutrition (2006) [E3]
Co-authors Robin Callister
2006 Wood LG, Garg ML, Powell HG, Gibson PG, 'Dietary lycopene and asthma control: A randomized control trial', Asia Pacific Journal of Clinical Nutrition (2006) [E3]
Co-authors Lisa Wood, Peter Gibson
2006 Micallef MA, Garg ML, Wood LG, Murphy VE, Clifton VL, 'Dietry intake of long chain n-3 polyunsaturated fatty acids in adults with asthma', Asia Pacific Journal of Clinical Nutrition (2006) [E3]
Co-authors Lisa Wood, Vicki Clifton, Vanessa Murphy
2006 Saedisomeolia A, Garg ML, Wood LG, Gibson PG, 'Lycopene supplementation does not influence cytokine profile in asthma patients', Asia Pacific Journal of Clinical Nutrition (2006) [E3]
Co-authors Lisa Wood, Peter Gibson
2006 Wood LG, Garg ML, Gibson PG, 'A low antioxidant diet worsens asthma control', Respirology (2006) [E3]
Co-authors Peter Gibson, Lisa Wood
2006 Wood LG, Garg ML, Powell H, Gibson PG, 'Modifying Dietary Antioxidant Consumption Affects Clinical Status and Noneosinophilic Airway Inflammation in Asthma', Respirology (2006) [E3]
Co-authors Peter Gibson, Lisa Wood
2006 Watson J, Collins CE, Sibbritt DW, Dibley MJ, Garg ML, 'Validation of a child and adolescent food-frequency', Obesity Review 7(2) (Abstracts of the 10th International Congress on Obesity) (2006) [E3]
Co-authors Clare Collins
2006 Lazarus S, Garg ML, Bowen K, 'Clarified Tomato Juice Inhibits Platelet Aggregation', Proceedings of the IXth International Symposium on the Processing Tomato (2006) [E1]
2005 Wood LG, Garg ML, Blake RJ, Simpson JL, Gibson PG, 'Systemic and airway levels of glutathione and alpha-tocopherol in asthma', Asia Pacific Journal of Clinical Nutrition (2005) [E3]
Co-authors Jodie Simpson, Peter Gibson, Lisa Wood
2005 Watson TA, Callister R, Garg ML, 'Vitamin E and fish oil effects on oxidative stress, antioxidant defences and responses to exercise in athletes', Dietitians Association of Australia (2005) [E3]
Co-authors Robin Callister
2005 Marley AM, Sibbritt DW, Garg ML, 'Poor adherence to a high-protein diet in type 2 diabetes', Dietitians Association of Australia Program and Abstracts (2005) [E3]
2005 Watson JF, Collins CE, Sibbritt DW, Garg ML, Dibley MJ, 'Overweight and obesity in Hunter primary school children and its association with consumption of nutrient dense snacks and sugary drinks', Dietitians Association of Australia Program and Abstracts (2005) [E3]
Co-authors Clare Collins
2005 Garg ML, 'Pycnogenol: A Potential Anti-Ageing Molecule', Healthy Ageing and Longevity (2005) [E3]
2004 Watson TA, Blake RJ, Callister R, MacDonald-Wicks LK, Garg ML, 'Antioxidant restricted diet reduces plasma non-esterified fatty acids in trained athletes', Asia Pacific Journal of Clinical Nutrition (2004) [E3]
Co-authors Robin Callister, Lesley Wicks
2004 Lazarus S, Garg ML, 'Inhibition of platelet aggregation from people with type 2 diabetes mellitus following consumption of tomato juice', Asia Pacific Journal of Clinical Nutrition (2004) [E3]
2004 MacDonald-Wicks LK, Gibson L, Godfrey D, Green J, Horan B, Monger K, et al., 'Oxidised LDL in newly diagnosed Type 2 diabetes mellitus and impaired glucose tolerance', Asia Pacific Journal of Clinical Nutrition (2004) [E3]
Co-authors Lesley Wicks
2004 Collins CE, Watson JF, Sibbritt DW, Dibley MJ, Garg ML, 'Short term trends in BMI in Hunter school-aged children', ASSO 13th Annual Scientific Meeting: Meeting Proceedings & Abstract Book (2004) [E3]
Co-authors Clare Collins
2004 Wood LG, Garg ML, Blake RJ, Gibson PG, 'Carotenoid concentrations in asthmatics versus healthy controls', Asia Pacific Journal of Clinical Nutrition (2004) [E3]
Co-authors Peter Gibson
2004 Collins CE, Watson JF, Garg ML, Dibley MJ, Sibbritt DW, 'Developing a food-frequency questionnaire for Australian kids', DAA NSW 10th State Conference: The Obesity Epidemic (2004) [E3]
Co-authors Clare Collins
2004 Garg ML, Lazarus S, 'Synergistic effect of tomato extract and omega-3 fatty acids on inhibition of platelet aggregation', IFT Annual Meeting and Food Expo 2004 (2004) [E4]
2004 Garg ML, 'What research do we need in Nutrition & Dietetics?', Nutrition on the Cutting Edge: From paddock to plate (2004) [E3]
2003 Byles J, Parkinson L, Collins C, Garg M, D'Este C, Dibley M, 'The Feasibility of Nutrition Screening Among Hospitalised Older People', AUSTRALASIAN JOURNAL ON AGEING (2003)
Co-authors L Parkinson, Clare Collins, Julie Byles, Catherine Deste
2003 Watson JF, Collins CE, Sibbritt DW, Dibley MJ, Garg ML, 'Prevalence of overweight, obesity and lifestyle factors in Hunter primary school children', ASSO 12th Annual Scientific Meeting Proceedings and Abstract Book (2003) [E3]
Co-authors Clare Collins
2003 Watson TA, Callister R, Taylor RD, Sibbritt DW, MacDonald-Wicks LK, Garg ML, 'High antioxidant foods protect against oxidative stress during acute exhaustive exercise in athletes', Proceedings of the Australian Conference of Science and Medicine in Sport (2003) [E3]
Co-authors Robin Callister, Lesley Wicks
2003 Watson TA, Callister R, Taylor RD, Sibbritt DW, MacDonald-Wicks LK, Garg ML, 'Antioxidant restriced diet increases oxidative stress during acute exhaustive exercise', Proceedings published in Asia Pacific Journal of Clinical Nutrition v12 S9 (2003) [E3]
Co-authors Lesley Wicks, Robin Callister
2003 Rashidi A, Mohammadpour B, Razzaghy-Azar M, Garg ML, Anbari MA, Kimiagar M, 'Serum zinc levels negatively correlated with diabetes duration in type 1 diabetic children', Annals of Nutrition & Metabolism (2003) [E4]
2003 Lazarus SA, Dutta-Roy AK, Garg ML, 'Inhibition of platelet aggregation by aqueous tomato extract', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2003)
2003 Watson JF, Collins CE, Garg ML, Dibley MJ, Sibbritt DW, 'Development of a food-frequency questionnaire for school-aged children', 21st National Conference of the Dietitians Association of Australia (2003) [E4]
Co-authors Clare Collins
2003 Tuka B, Collins CE, Alvaro F, Marshall G, Garg ML, 'Risk factors for malnutrition in paediatric oncology patients', 21st National Conference of the Dietitians Association of Australia (2003) [E4]
Co-authors Clare Collins
2003 Watson JF, Collins CE, Dibley MJ, Garg ML, Sibbritt DW, 'Design considerations in the development of a food-frequency questionnaire for school-aged children', Asia Pacific Journal of Clinical Nutrition (2003) [E4]
Co-authors Clare Collins
2003 Watson TA, Callister R, Sibbritt DW, MacDonald-Wicks LK, Garg ML, 'Antioxidant restricted diet increases oxidative stress during acute exhaustive exercise', Asia Pacific Journal of Clinical Nutrition (2003) [E4]
Co-authors Lesley Wicks, Robin Callister
2003 Lazarus S, Garg ML, 'The effects of tomato extract and omega-3 fatty acids on platelet cAMP levels and inositol triphosphate release', Asia Pacific Journal of Clinical Nutrition (2003) [E4]
2002 Adams MC, Huang Y, Kotula L, Blake R, Garg M, 'The efficacy of a potential new probiotic, Propionibacterium jensenii 702, to correct vitamin B12 levels in an in vivo deficient animal model', Asia Pacific Journal of Clinical Nutrition (2002) [E1]
Citations Scopus - 5
2002 Adams MC, Huang Y, Blake RJ, Garg ML, 'The efficacy of a potential new probiotic, Propionibacterium jensenii 702, to correct vitamin B12 levels in an in vivo deficient animal model', Proceedings of the Nutrition Society of Australia, Volume 26 (2002) [E3]
2002 MacDonald-Wicks LK, Garg ML, 'Oxidative stress induced by omega-3 fatty acids is dependent on background fatty acid composition', Proceedings of the Nutrition Society of Australia, Volume 26 (2002) [E3]
Co-authors Lesley Wicks
2002 Watson TA, MacDonald-Wicks LK, Garg ML, 'Regular exercise training does not elevate oxidative stress or deplete antioxidant defences', Proceedings of the Nutrition Society of Australia, Volume 26 (2002) [E3]
Citations Scopus - 1
Co-authors Lesley Wicks
2002 Perkin SA, Dutta-Roy AK, Garg ML, 'Aqueous tomato extract inhibits platelet aggregation', Proceedings of the Nutrition Society of Australia, Volume 26 (2002) [E3]
Citations Scopus - 1
2002 Volker DH, Katz T, Shui LKC, Quaggiotto P, Garg ML, Major GAC, 'Nutrition in inflammatory disease: what is the evidence?', Proceedings of the Nutrition Society of Australia, Volume 26 (2002) [E3]
2002 MacDonald-Wicks LK, Garg ML, 'High fat diets do not increase CCl4-induced oxidative stress in the rat', Proceedings of the Nutrition Society of Australia, Volume 26 (2002) [E3]
Co-authors Lesley Wicks
2002 Garg ML, Bencke AJ, Blake RJ, 'Effects of fish oil (MaxEPA) supplementation on fatty acid profile and platelet activating factor generation in human buccal mucosal cells', Proceedings of the Nutrition Society of Australia, Volume 26 (2002) [E3]
2002 Collins CE, Tuka EB, Alvaro F, Marshall G, Garg ML, 'Risk factors for malnutrition in paediatric oncology patients', 9th World Congress on Clinical Nutrition Abstracts (2002) [E3]
Co-authors Clare Collins
2002 Garg ML, 'Health benefits of macadamia nuts in borderline hypercholesterolemic male volunteers', 9th World Congress on Clinical Nutrition Abstracts (2002) [E3]
2002 Garg ML, Blake RJ, Leitch JW, 'Incorporation of n-3 polyunsaturated fatty acids into atrial myocardium of coronary bypass patients following supplementation with a fish oil concentrate', 93rd AOCS Annual Meeting & Expo Abstracts (2002) [E3]
2002 Garg ML, Rudra PK, Blake RJ, Wills RBH, 'Health benefits of Macadamia nuts', 93rd AOCS Annual Meeting & Expo Abstracts (2002) [E3]
2001 Tuka E, Alvaro F, Garg ML, Lessem R, Collins CE, 'Parental concerns, nutrition and wellbeing in paediatric oncology patients undergoing treatment', Medical and Pediatric Oncology, Volume 37 (3) (2001) [E3]
Co-authors Clare Collins
2001 Tuka E, Alvaro F, Garg ML, Lessem R, Collins CE, 'Nutritional, oxidant and antioxidant status in paediatric oncology patients undergoing treatment', Medical and Pediatric Oncology, Volume 37 (3) (2001) [E3]
Co-authors Clare Collins
2001 Garg ML, Rudra PK, Blake RJ, Wills R, 'Health benefits of macadamia nuts in borderline hypercholesterolaemic volunteers', Asia Pacific Journal of Clinical Nutrition (2001) [E4]
2001 Garg ML, Rudra PK, Blake RJ, Wills RB, 'Health benefits of macadamia nuts in borderline hyperlipidaemic male volunteers', Proceedings of the Nutrition Society of Australia (2001) (2001) [E1]
Co-authors Ron Wills
2000 Fitzgerald D, Wood LG, Gibson PG, Cooper D, Garg ML, 'Elevated plasma levels of 8-iso-PGF2a in asthma', American Journal of Respiratory and Critical Care Medicine ISSN 1073-449X (2000) [E3]
Co-authors Lisa Wood, Peter Gibson
2000 MacDonald-Wicks LK, Garg ML, 'Vitamin E in the mitigation of carbon tetrachloride induced oxidative stress in rats', Proceedings of the 24th Annual Scientific Meeting, Nutrition Society of Australia (2000) [E3]
Co-authors Lesley Wicks
2000 MacDonald-Wicks LK, Garg ML, 'Dietary fat type and the mitigation of carbon tetrachloride-induced oxidative stress in rats', Proceedings of the 24th Annual Scientific Meeting, Nutrition Society of Australia (2000) [E3]
Co-authors Lesley Wicks
2000 Wood LG, Garg ML, 'Cystic Fibrosis - the Human Model of Oxidative Stress', Proceedings of the 8th World Congress of Clinical Nutrition (2000) [E3]
Co-authors Lisa Wood
2000 MacDonald-Wicks LK, Garg ML, 'Animal Models of Induced Oxidative Stress: Advantages and Limitations', Proceedings of the 8th World Congress of Clinical Nutrition (2000) [E3]
Co-authors Lesley Wicks
2000 Rudra PK, Blake RJ, Wills R, Garg ML, 'Health Effects of Monounsaturated Fats', Proceedings of the 8th World Congress of Clinical Nutrition (2000) [E3]
2000 Garg ML, 'Antioxidants in the New Millennium', Proceedings of the 8th World Congress on Clinical Nutrition (2000) [E3]
2000 Van Gerven DA, Munro IA, Garg ML, 'Consumers knowledge, attitudes and behavior with respect to consuming dietary fats and oils', Proceedings of the Nutrition Society of Australia (2000) [E3]
2000 Garg ML, Rudra PK, Blake RJ, Wills R, 'Plasma cholesterol levels are not elevated following macadamia nut consumption in healthy male young volunteers', Proceedings of the Nutrition Society of Australia (2000) [E3]
2000 Blake RJ, Leitch J, Garg ML, 'Incorporation of n-3 polyunsaturated fatty acids into atrial myocardium of coronary bypass patients following supplementation with a fish oil concentrate', Proceedings of the Nutrition Society of Australia (2000) [E3]
1999 Wood LG, Fitzgerald D, Gibson PG, Cooper D, Collins CE, Garg ML, 'Isoprostanes as a Novel Marker of Oxidative Stress in Cystic Fibrosis', 3rd Australian Cystic Fibrosis Conference (1999) [E3]
Co-authors Lisa Wood, Peter Gibson, Clare Collins
1999 Volker DH, Fitzgerald P, Garg ML, 'The Influence of Fish Oil on the Pathogenesis of Streptococcal Cell Wall (SCW) Polymers Induced Arthritis in the Lew/SSN Rat', Weighing the Evidence Programme and Proceedings (1999) [E3]
1999 Wood LG, Fitzgerald D, Gibson PG, Cooper D, Collins CE, Garg ML, '8-ISO-PGF2a and Oxidative Stress in Cystic Fibrosis', Weighing the Evidence Programme and Proceedings (1999) [E3]
Co-authors Peter Gibson, Lisa Wood, Clare Collins
1999 Nair S, Leitch J, Garg ML, 'Inositol phosphate release in cardiac myocytes isolated from fish oil supplemented pigs', Weighing the Evidence Programme and Proceedings (1999) [E3]
1999 Nair S, Leitch J, Garg ML, 'Protein Kinase C activity in adult porcine cardiac myocyte supplemented with n-3 polyunsaturated fatty acids', Weighing the Evidence Programme and Proceedings (1999) [E3]
1999 Nair S, Leitch J, Garg ML, 'N-3 polyunsaturated fatty acids supplementation alters release of inositol phosphates in adult porcine cardiac myocytes', Weighing the Evidence Programme and Proceedings (1999) [E3]
1998 Nair S, Leitch J, Garg ML, 'Modification of specific fatty acid pools in cultured porcine cardiomyocytes after n-3 polyunsaturated fatty acid supplementation', Proceedings of the Nutrition Society of Australia (1998) [E3]
1998 Volker DH, Major G, Garg ML, 'N-6 PUFA in the background diet and the effect of N-3 PUFA supplementation in rheumatoid arthritis', Proceedings of the Nutrition Society of Australia (1998) [E3]
1998 Wood LG, Fitzgerald D, Cooper D, Gibson PG, Garg ML, 'Antioxidant defenses in cystic fibrosis patients', Proceedings of the Nutrition Society of Australia (1998) [E3]
Co-authors Lisa Wood, Peter Gibson
1998 Quaggiotto P, Powis D, Garg ML, 'Catecholamine secretion in cultured bovine chromaffin cells modified by polyunsaturated fatty acid supplementation', Proceedings of the Nutrition Society of Australia (1998)22 (1998) [E3]
1997 Garg ML, Blake R, 'Cholesterol dynamics in rats fed diets containing either canola oil or sunflower oil', NUTRITION RESEARCH (1997)
DOI 10.1016/S0271-5317(97)00009-2
Citations Scopus - 18Web of Science - 19
1996 Reinhard BL, Blake R, Garg ML, 'Effect of dietary n-6 and n-3 fatty acids on phospholipid fatty acid composition of rat stomach, jejunum and colon', PROCEEDINGS OF THE NUTRITION SOCIETY OF AUSTRALIA, VOL 20 (1996)
1996 Nair SSD, Leitch JL, Falconer J, Garg ML, 'Effect of dietary fish oil (MAXEPA) supplementation on non-esterified fatty acid composition and content of porcine myocardium', PROCEEDINGS OF THE NUTRITION SOCIETY OF AUSTRALIA, VOL 20 (1996)
1996 Volker DH, Major GAC, Garg ML, 'Total fat, cholesterol, n-6 and n-3 fatty acid intake in rheumatoid and osteoarthritis patients', PROCEEDINGS OF THE NUTRITION SOCIETY OF AUSTRALIA, VOL 20 (1996)
1994 GARG ML, JANSEN M, 'Dietary N-6 and N-3 fatty acids affect faecal cholesterol excretion in rats via different mechanisms', PROCEEDINGS OF THE NUTRITION SOCIETY OF AUSTRALIA, VOL 18 (1994)
1994 GARG ML, 'Metabolic fate of cholesterol in rats fed diets containing canola oil or safflower oil', PROCEEDINGS OF THE NUTRITION SOCIETY OF AUSTRALIA, VOL 18 (1994)
1992 CLANDININ MT, GARG ML, PARROTT A, VANAERDE J, HERVADA A, LIEN E, 'ADDITION OF LONG-CHAIN POLYUNSATURATED FATTY-ACIDS TO FORMULA FOR VERY-LOW-BIRTH-WEIGHT INFANTS', LIPIDS (1992)
DOI 10.1007/BF02535869
Citations Scopus - 29Web of Science - 27
1992 GARG ML, CLANDININ MT, 'ALPHA-LINOLENIC ACID AND METABOLISM OF CHOLESTEROL AND LONG-CHAIN FATTY-ACIDS', NUTRITION (1992)
Citations Scopus - 9Web of Science - 8
1990 GARG ML, KEELAN M, THOMSON ABR, CLANDININ MT, 'INTESTINAL MICROSOMES - POLYUNSATURATED FATTY-ACID METABOLISM AND REGULATION OF ENTEROCYTE TRANSPORT-PROPERTIES', CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (1990)
Citations Scopus - 16Web of Science - 16
1990 KEELAN M, THOMSON ABR, GARG ML, CLANDININ MT, 'CRITICAL PERIOD PROGRAMMING OF INTESTINAL GLUCOSE-TRANSPORT VIA ALTERATIONS IN DIETARY FATTY-ACID COMPOSITION', CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (1990)
Citations Scopus - 11Web of Science - 12
Show 200 more conferences

Patent (1 outputs)

Year Citation Altmetrics Link
2006 Gibson PG, Wood LG, Garg ML, Method for evaluating status of asthma control (2006) [I3]
Co-authors Lisa Wood, Peter Gibson

Other (2 outputs)

Year Citation Altmetrics Link
Garg ML, Fulton AS, Coates AM, Williams MT, Howe PRC, Frith PA, et al., 'Feasibility of a randomised controlled trial of fish oil supplementation in people with chronic obstructive pulmonary disease', [O1]
Co-authors Lisa Wood
Garg ML, Abbott K, Thota R, Burrows T, Acharya S, 'Systematic review and meta-analysis of the relationship between omega-3 long-chain polyunsaturated fatty acids and insulin resistance', [O1]
Co-authors Tracy Burrows
Edit

Grants and Funding

Summary

Number of grants 71
Total funding $7,815,457

Click on a grant title below to expand the full details for that specific grant.


20173 grants / $113,603

Complementary and/or synergistic effects of Phytosterols and Curcumin for reducing Cardiovascular Disease Risk in Hyperlipidaemic Individuals$55,110

Funding body: BASF (Asia Pacific)

Funding body BASF (Asia Pacific)
Project Team Professor Manohar Garg, Mrs Jessica Ferguson
Scheme Newtrition Asia Research Grant
Role Lead
Funding Start 2017
Funding Finish 2017
GNo G1601199
Type Of Funding International - Competitive
Category 3IFA
UON Y

Long chain omega-3 polyunsaturated fatty acids for the prevention of gestational diabetes: A double-blind randomized controlled trial$53,493

Funding body: BASF (Asia Pacific)

Funding body BASF (Asia Pacific)
Project Team Professor Manohar Garg, Mrs Kylie Abbott, Doctor Sham Acharya, Associate Professor Tracy Burrows, Ms Katie-Jane Wynne, Dr Wendy Carseldine
Scheme Newtrition Asia Research Grant
Role Lead
Funding Start 2017
Funding Finish 2018
GNo G1601197
Type Of Funding International - Competitive
Category 3IFA
UON Y

Optimising lipid-lowering ability of dietary phytosterols for reducing cardiovascular disease risk$5,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Manohar Garg, Doctor Lesley MacDonald-Wicks, Doctor Elizabeth Stojanovski
Scheme Postgraduate Research Scholarship
Role Lead
Funding Start 2017
Funding Finish 2017
GNo G1700528
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20162 grants / $52,556

Lipid metabolism and improved cardiovascular health$45,836

Funding body: Riddet Institute

Funding body Riddet Institute
Project Team Professor Manohar Garg
Scheme Research Grant
Role Lead
Funding Start 2016
Funding Finish 2017
GNo G1601403
Type Of Funding International - Competitive
Category 3IFA
UON Y

Efficacy of a dietary program for the treatment of major depressive episodes$6,720

Funding body: La Trobe University

Funding body La Trobe University
Project Team Professor Manohar Garg
Scheme Research Project
Role Lead
Funding Start 2016
Funding Finish 2016
GNo G1600950
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20146 grants / $4,947,693

Pork consumption and serum irisin levels in type 2 diabetes$50,300

Funding body: CRC for High Integrity Australian Pork

Funding body CRC for High Integrity Australian Pork
Project Team Professor Manohar Garg, Professor Peter Howe, Doctor Rachel Wong
Scheme Innovative Research
Role Lead
Funding Start 2014
Funding Finish 2015
GNo G1400612
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Post-pradial effects of almond lipids on cardiovascular disease risk (Cardiovascular Program Bridge Funding)$30,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Manohar Garg
Scheme Project Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1400457
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Dose response evaluation of resveratrol supplementation on cerebrovascular function, mood and cognitive performance in type 2 diabetes mellitus$27,047

Funding body: DSM Nutritional Products AG

Funding body DSM Nutritional Products AG
Project Team Professor Peter Howe, Doctor Rachel Wong, Professor Manohar Garg, Professor Andrew Scholey
Scheme Research Project
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1400950
Type Of Funding International - Non Competitive
Category 3IFB
UON Y

Saturated fats may promote cardiovascular health$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Manohar Garg, Professor Lisa Wood
Scheme Project Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1401400
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Sub-Project - Hunter Cancer Research Alliance; HCRA$15,000

Funding body: Cancer Institute NSW

Funding body Cancer Institute NSW
Project Team Professor Manohar Garg, Dr Jennette Sakoff, Dr James Lynam, Professor Jennifer Martin, Doctor Cintia Dias
Scheme Translational Cancer Research Centre Grants
Role Lead
Funding Start 2014
Funding Finish 2019
GNo GS170008
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

20132 grants / $215,000

Clinical evaluation of a novel olive leaf formulation for heart health$165,000

Funding body: Newcastle Innovation

Funding body Newcastle Innovation
Project Team Professor Peter Howe, Professor Manohar Garg, Doctor Rachel Wong, Professor Lisa Wood
Scheme Administered Research
Role Investigator
Funding Start 2013
Funding Finish 2014
GNo G1401244
Type Of Funding Internal
Category INTE
UON Y

Lipemic Index of Pork$50,000

Funding body: CRC for High Integrity Australian Pork

Funding body CRC for High Integrity Australian Pork
Project Team Professor Manohar Garg, Professor Lisa Wood, Professor Peter Howe
Scheme Innovative Research
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1201031
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20122 grants / $47,000

Dietary fructose restriction improves plasma lipids, satiety hormones and inflammation in obesity$45,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Manohar Garg, Professor Lisa Wood
Scheme Project Grant
Role Lead
Funding Start 2012
Funding Finish 2014
GNo G1101123
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

22nd Annual Conference of the ISH (incorporating International Conference on CVD Prevention), Mumbai, India, 2 - 3 November 2012$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Professor Manohar Garg
Scheme Travel Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1200997
Type Of Funding Internal
Category INTE
UON Y

20111 grants / $321,711

Physical Activity and Nutrition: The University of Newcastle's Approach Toward Better Population Health and Education$321,711

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Ronald Plotnikoff, Professor Robin Callister, Professor Clare Collins, Doctor Benjamin Ewald, Professor Manohar Garg, Associate Professor Erica James, Professor David Lubans, Professor Philip Morgan
Scheme Priority Research Centre
Role Investigator
Funding Start 2011
Funding Finish 2015
GNo G1100058
Type Of Funding Internal
Category INTE
UON Y

20106 grants / $174,117

HMRI MRSP Infrastructure Grant (10-11) - Cardiovascular$76,117

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Derek Laver, Professor Dirk Van Helden, Associate Professor Eugene Nalivaiko, Associate Professor Liz Milward, Professor Robert Callister, Professor Manohar Garg, Conjoint Professor Tony Quail
Scheme NSW MRSP Infrastructure Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G1100525
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Long chain omega-3 poly unsaturated fatty acid and platelet function$50,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Manohar Garg
Scheme Scholarships - Medical and Dental Postgraduate Research
Role Lead
Funding Start 2010
Funding Finish 2011
GNo G0190538
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

ABI 7500 Real Time PCR System $34,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Rick Thorne, Doctor Nikki Verrills, Professor Murray Cairns, Associate Professor Paul Tooney, Associate Professor Doug Smith, Professor Gordon Burns, Emeritus Professor Leonie Ashman, Conjoint Professor Keith Jones, Doctor Charles De Bock, Associate Professor Chris Dayas, Associate Professor Brett Graham, Doctor Martin Horan, Doctor Rebecca Lim, Doctor Severine Roselli, Doctor Larisa Bobrovskaya, Doctor Kathryn Skelding, Associate Professor Rohan Walker, Doctor Jude Weidenhofer, Professor Philip Bolton, Professor Alan Brichta, Professor Robert Callister, Professor Trevor Day, Associate Professor Phillip Dickson, Professor Manohar Garg, Doctor Phil Jobling, Professor Derek Laver, Associate Professor Eugene Nalivaiko, Emeritus Professor John Rostas
Scheme Equipment Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G1000055
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

ASE - Supervisor of the Year 2010$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Award for Supervision Excellence
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G1001074
Type Of Funding Internal
Category INTE
UON Y

15th World Congress on Clinical Nutrition, El Sokhna, Egypt, 19 - 22 September 2010$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Professor Manohar Garg
Scheme Travel Grant
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G1000531
Type Of Funding Internal
Category INTE
UON Y

ASE - Faculty of Health$2,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Award for Supervision Excellence
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G1001030
Type Of Funding Internal
Category INTE
UON Y

20086 grants / $281,690

Docosapentaenoic acid (22:5n-3) is a functional long-chain w3 PUFA$93,500

Funding body: Meat and Livestock Australia

Funding body Meat and Livestock Australia
Project Team Professor Manohar Garg
Scheme Human Nutrition Research Program
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0188164
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Exploring the link between obesity and asthma$75,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Lisa Wood, Conjoint Professor Peter Gibson, Professor Manohar Garg
Scheme Post Graduate Support Grant
Role Investigator
Funding Start 2008
Funding Finish 2010
GNo G0188479
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Exploring the link between asthma and obesity$66,771

Funding body: CCRE in Respiratory and Sleep Medicine

Funding body CCRE in Respiratory and Sleep Medicine
Project Team Professor Lisa Wood, Conjoint Professor Peter Gibson, Professor Manohar Garg, Ms Hayley Scott
Scheme Postgraduate Research Scholarship
Role Investigator
Funding Start 2008
Funding Finish 2010
GNo G0188635
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Trans Fatty acids and airway inflammation$25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Lisa Wood, Conjoint Professor Peter Gibson, Professor Manohar Garg
Scheme Project Grant
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo G0188472
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

HMRI - Equipment Grant - High Speed Sensitivity CCD camera, centrifuge ELISA plate washer. etc$18,919

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Dirk Van Helden, Professor Manohar Garg
Scheme Equipment Grant
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo G0189386
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

13th World Congress on Clinical Nutrition, Xalapa, Veracruz, Mexico, 29/1/2008 - 1/2/2008$2,500

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Travel Grant
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0188458
Type Of Funding Internal
Category INTE
UON Y

20072 grants / $521,056

HMRI - Cardiovascular Research Program$518,556

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Derek Laver, Conjoint Professor Tony Quail, Professor Dirk Van Helden, Professor Manohar Garg, Professor Robin Callister
Scheme NSW MRSP Infrastructure Grant
Role Investigator
Funding Start 2007
Funding Finish 2009
GNo G0187946
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

12th World Congress on Clinical Nutrition, Edmonton, Alberta, Canada, 17/6/2007 - 20/6/2007$2,500

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Travel Grant
Role Lead
Funding Start 2007
Funding Finish 2007
GNo G0187917
Type Of Funding Internal
Category INTE
UON Y

20062 grants / $26,000

Omega-3 fatty acid supplementation for sustainable weight loss$16,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Manohar Garg
Scheme Project Grant
Role Lead
Funding Start 2006
Funding Finish 2006
GNo G0186101
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Lipid lowering potential of combined phytosterols and long chain omega-3 fatty acids$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Pilot Grant
Role Lead
Funding Start 2006
Funding Finish 2006
GNo G0186697
Type Of Funding Internal
Category INTE
UON Y

20052 grants / $342,070

The role of lycopene supplementation in the management of asthma$328,750

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Professor Manohar Garg
Scheme Project Grant
Role Investigator
Funding Start 2005
Funding Finish 2007
GNo G0183939
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

2005 RIBG allocation$13,320

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Research Infrastructure Block Grant (RIBG)
Role Lead
Funding Start 2005
Funding Finish 2005
GNo G0185786
Type Of Funding Internal
Category INTE
UON Y

20043 grants / $55,600

Potential benefits of a higher protein diet for people with type 2 diabetes$37,200

Funding body: Diabetes Australia

Funding body Diabetes Australia
Project Team Professor Manohar Garg
Scheme Research Grant
Role Lead
Funding Start 2004
Funding Finish 2004
GNo G0183190
Type Of Funding Aust Competitive - Non Commonwealth
Category 1NS
UON Y

Omega 3-fatty acids, tomato extract and platelet function in NIDDM patients.$16,000

Funding body: Novo Nordisk Foundation

Funding body Novo Nordisk Foundation
Project Team Professor Manohar Garg, Doctor Kerry Bowen
Scheme Regional Diabetes Support Scheme
Role Lead
Funding Start 2004
Funding Finish 2004
GNo G0184020
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Institute of Food Technologists Annual Meeting and Food Expo, Las Vegas, 12-16 July 2004$2,400

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Travel Grant
Role Lead
Funding Start 2004
Funding Finish 2004
GNo G0184077
Type Of Funding Internal
Category INTE
UON Y

20032 grants / $30,000

Carotenoids and flavonoids in asthma$15,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Conjoint Professor Peter Gibson, Professor Manohar Garg, Professor Lisa Wood
Scheme Project Grant
Role Investigator
Funding Start 2003
Funding Finish 2003
GNo G0182435
Type Of Funding Internal
Category INTE
UON Y

Oxidative stress and antioxidant responses to acute exercise.$15,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg, Professor Robin Callister
Scheme Project Grant
Role Lead
Funding Start 2003
Funding Finish 2003
GNo G0182494
Type Of Funding Internal
Category INTE
UON Y

20024 grants / $115,500

Diet, nutrition and lifestyle factors in the development and treatment of overweight and obesity in children.$90,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Clare Collins, Professor Manohar Garg, Doctor Michael Dibley
Scheme Kiriwina Investment Group
Role Investigator
Funding Start 2002
Funding Finish 2004
GNo G0182526
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Feasibility of nutrition screening among the elderly$13,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Julie Byles, Professor Clare Collins, Doctor Michael Dibley, Conjoint Professor Cate d'Este, Professor Manohar Garg
Scheme Project Grant
Role Investigator
Funding Start 2002
Funding Finish 2002
GNo G0181275
Type Of Funding Internal
Category INTE
UON Y

The use of Propioibacteria sp. bacteria as an alternate source of dietary Vitamin B12$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Michelle Adams, Professor Manohar Garg
Scheme Project Grant
Role Investigator
Funding Start 2002
Funding Finish 2002
GNo G0181389
Type Of Funding Internal
Category INTE
UON Y

9th World Congress on Clinical Nutrition London, UK, June 24 - 26, 2002$2,500

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Travel Grant
Role Lead
Funding Start 2002
Funding Finish 2002
GNo G0181831
Type Of Funding Internal
Category INTE
UON Y

20012 grants / $25,000

Oxidative stress and the antioxidant defences in asthmatic airways in relation to disease severity.$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Conjoint Professor Peter Gibson, Professor Manohar Garg
Scheme Research Grant
Role Investigator
Funding Start 2001
Funding Finish 2001
GNo G0181501
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Vitamin E supplementation in Hypercholestrolemic subjects and serum levels of autoantibodies against oxidised low density lypoproteins (Ox-LDL).$5,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Project Grant
Role Lead
Funding Start 2001
Funding Finish 2001
GNo G0179936
Type Of Funding Internal
Category INTE
UON Y

20005 grants / $74,105

Nutritional status of children undergoing chemotherapy: A cross-sectional view.$32,000

Funding body: John Hunter Children`s Hospital Research Foundation

Funding body John Hunter Children`s Hospital Research Foundation
Project Team Professor Clare Collins, Professor Manohar Garg
Scheme Research Grant (Defunct)
Role Investigator
Funding Start 2000
Funding Finish 2000
GNo G0180152
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Increasing consumer preference for monosaturated fats and oils.$20,000

Funding body: Meadow Lea Foods

Funding body Meadow Lea Foods
Project Team Professor Manohar Garg
Scheme GRDC Nutritional Research Program
Role Lead
Funding Start 2000
Funding Finish 2000
GNo G0179338
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Oxidative Stress and Antioxidant Supplementation in Cystic Fibrosis$12,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg, Dr Dominic Fitzgerald
Scheme Project Grant
Role Lead
Funding Start 2000
Funding Finish 2000
GNo G0178779
Type Of Funding Internal
Category INTE
UON Y

The relationship between dietary intake of anti-oxidants and pregnancy-induced hypertension:a case-control study of women attending John Hunter Hospital for ant$8,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Conjoint Associate Professor Andrew Bisits, Professor Manohar Garg, Doctor Michael Dibley, Dr David Jeacocke
Scheme Project Grant
Role Investigator
Funding Start 2000
Funding Finish 2000
GNo G0178971
Type Of Funding Internal
Category INTE
UON Y

8th World Congress and Clinical Nutrition, Thailand 17-20 December 2000$2,105

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Travel Grant
Role Lead
Funding Start 2000
Funding Finish 2000
GNo G0179854
Type Of Funding Internal
Category INTE
UON Y

19996 grants / $219,481

Hind gut function in laying hens$133,354

Funding body: Rural Industries Research & Development Corporation

Funding body Rural Industries Research & Development Corporation
Project Team Dr Robert Taylor, Professor Manohar Garg
Scheme Research and Development Project
Role Investigator
Funding Start 1999
Funding Finish 2001
GNo G0178398
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Health Benefits of Macadamia Nuts$44,265

Funding body: Horticultural Research & Development Corporation

Funding body Horticultural Research & Development Corporation
Project Team Professor Manohar Garg, Emeritus Professor Ronald Wills
Scheme Research Grant
Role Lead
Funding Start 1999
Funding Finish 1999
GNo G0177654
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

RMC COLLAB PARTNER. Oxidative Stress and Monounsaturated Oils$19,756

Funding body: Meadow Lea Foods

Funding body Meadow Lea Foods
Project Team Professor Manohar Garg
Scheme Research Grant
Role Lead
Funding Start 1999
Funding Finish 1999
GNo G0178353
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

n-3 polyunsaturated fatty acids and cell signalling.$11,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg, Conjoint Professor David Powis
Scheme Project Grant
Role Lead
Funding Start 1999
Funding Finish 1999
GNo G0178154
Type Of Funding Internal
Category INTE
UON Y

Oxidative Stress and Monounsaturated Oils$9,931

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Collaborative Research Grant
Role Lead
Funding Start 1999
Funding Finish 1999
GNo G0178325
Type Of Funding Internal
Category INTE
UON Y

Pacific Parners in Nutrition and Dietetics Auckland, New Zealand.$1,175

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Travel Grant
Role Lead
Funding Start 1999
Funding Finish 1999
GNo G0179093
Type Of Funding Internal
Category INTE
UON Y

19982 grants / $23,000

Fatty acid modification of phospholipase C mediated responses.$14,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Dr Stephen Bunn, Professor Manohar Garg, Conjoint Professor David Powis
Scheme Project Grant
Role Investigator
Funding Start 1998
Funding Finish 1998
GNo G0177206
Type Of Funding Internal
Category INTE
UON Y

Anti-inflammatory Effects of Dietary n-3 Fatty Acid Supplementation in Rheumatoid Arthritis.$9,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg, Doctor Gabor Major
Scheme Project Grant
Role Lead
Funding Start 1998
Funding Finish 1998
GNo G0177253
Type Of Funding Internal
Category INTE
UON Y

19974 grants / $66,500

Replacement of fat in dietary products: fundamentals and applications.$40,000

Funding body: Sara Lee (Australia) Pty Ltd

Funding body Sara Lee (Australia) Pty Ltd
Project Team Professor Manohar Garg, Professor Simon Biggs, Laureate Professor Kevin Galvin
Scheme Research Grant
Role Lead
Funding Start 1997
Funding Finish 1998
GNo G0177530
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Non-Esterified Fatty Acids and Cardiac Arrhythmias.$14,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Manohar Garg, Ian Leitch
Scheme Small Grant
Role Lead
Funding Start 1997
Funding Finish 1997
GNo G0176666
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

Efficacy of Fish Oil supplementation in the treatment of Rheumatoid Arthritis.$10,000

Funding body: Meadow Lea Foods

Funding body Meadow Lea Foods
Project Team Professor Manohar Garg
Scheme GRDC Nutritional Research Program
Role Lead
Funding Start 1997
Funding Finish 1997
GNo G0177478
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

6th World Congress on Clinical Nutrition, Alberta, Canada, 23-26 July 1997$2,500

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Travel Grant
Role Lead
Funding Start 1997
Funding Finish 1997
GNo G0179475
Type Of Funding Internal
Category INTE
UON Y

19963 grants / $93,080

Influence of dietary fat intake on cardiac electrophysiologic properties in the pig$76,834

Funding body: National Heart Foundation of Australia

Funding body National Heart Foundation of Australia
Project Team Conjoint Associate Professor James Leitch, Professor Manohar Garg, Dr John Falconer
Scheme Grant-In-Aid
Role Investigator
Funding Start 1996
Funding Finish 1997
GNo G0175465
Type Of Funding Aust Competitive - Non Commonwealth
Category 1NS
UON Y

Lipid metabolism in peritoneal macrophages during hyperlipidaemia$14,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Manohar Garg
Scheme Small Grant
Role Lead
Funding Start 1996
Funding Finish 1996
GNo G0175712
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

Lipids, Membranes &Thrombosis - The Netherlands - 10-13/7/96$2,246

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Travel Grant
Role Lead
Funding Start 1996
Funding Finish 1996
GNo G0176226
Type Of Funding Internal
Category INTE
UON Y

19952 grants / $17,081

Dietary N-3 fatty Acid Supplementation and Platelet Activating Factor (PAF) Generation in Human Buccal Mucosal Cells$15,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Project Grant
Role Lead
Funding Start 1995
Funding Finish 1995
GNo G0174904
Type Of Funding Internal
Category INTE
UON Y

5th World Conference on Clinical Nutriation, China, 3-5 Oct$2,081

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Travel Grant
Role Lead
Funding Start 1995
Funding Finish 1995
GNo G0176875
Type Of Funding Internal
Category INTE
UON Y

19941 grants / $22,000

Regulation of plasmalogen metabolism in the intestinal mucosa$22,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Manohar Garg, Professor D Roberts
Scheme Small Grant
Role Lead
Funding Start 1994
Funding Finish 1994
GNo G0174805
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

19933 grants / $31,614

Metabolic Fate of Dietary Cholesterol in Presence of Canola Oil or Safflower Oil$15,648

Funding body: Canola Council of Canada

Funding body Canola Council of Canada
Project Team Professor Manohar Garg
Scheme Canola Utilization Assistance Program
Role Lead
Funding Start 1993
Funding Finish 1993
GNo G0175490
Type Of Funding International - Non Competitive
Category 3IFB
UON Y

Dietary omega-3 fatty acids and fecal excretion of cholesterol and its metabolites.$14,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg, Professor D Roberts
Scheme New Staff Grant
Role Lead
Funding Start 1993
Funding Finish 1993
GNo G0173418
Type Of Funding Internal
Category INTE
UON Y

'4th World Congress on Clinical Nutrition' - Cochin/Moradabad, India - 2 - 12 Otober 1993$1,966

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Manohar Garg
Scheme Travel Grant
Role Lead
Funding Start 1993
Funding Finish 1993
GNo G0174362
Type Of Funding Internal
Category INTE
UON Y
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Research Supervision

Number of supervisions

Completed16
Current14

Total current UON EFTSL

PhD4.45

Current Supervision

Commenced Level of Study Research Title Program Supervisor Type
2017 PhD Neuroprotective Effects of Medium Chain Fatty Acids From Virgin Coconut Oil in Alzheimer's Disease PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2017 PhD Dietary Omega-3 Polyunsaturated Fatty Acid Supplementation and the Risk of Developing Type 2 Diabetes Mellitus PhD (Nutritional Biochemistry), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2017 PhD Synergistic Effects of Phytosterols and Curcumin on Cardiovascular Risk Factors in Hyperlipidaemic Individuals PhD (Nutritional Biochemistry), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2017 PhD Trimethylamine N-oxide (TMAO) Metabolite Among Healthy and Young Saudi Arabia Population. PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2016 PhD Differential effects of short, medium and long chain saturated fatty acids on cardiovascular disease risk factors PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2016 PhD Investigating Oxytocin as a biomarker to characterise Food Addiction PhD (Nutrition & Dietetics), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2014 PhD Anti-Inflammatory Bio-Active Compounds for Prevention of Type II Diabetes PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2007 PhD Food habits and prevalence of overweight/obesity in school children Medical Science, University of Newcastle Co-Supervisor
2007 PhD Asthma induced changes in fatty acid metabolism during prenancy Medical Science, University of Newcastle Co-Supervisor
2006 PhD Phytosterols and long chain omega-3 fatty acids in metabolic syndrome Medical Science, University of Newcastle Principal Supervisor
2006 PhD Phytosterols and long chain omega-3 fatty acids in the management of hyperlipidaemia Human Biology, University of Newcastle Principal Supervisor
2005 PhD Role of long chain omega-3 fatty acids in sustainable weight loss Medical Science, University of Newcastle Principal Supervisor
2004 PhD Antioxidants and inflammation in asthma Medical Science, University of Newcastle Principal Supervisor
2002 PhD Omega-3 fatty acids, carotenoids and inflammation in athletes Medical Science, University of Newcastle Principal Supervisor

Past Supervision

Year Level of Study Research Title Program Supervisor Type
2016 PhD Influence of Dietary Fructose on Lipid Profile and Glycaemic Control in Healthy Individuals PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2016 PhD Do Long Chain Omega-3 Polyunsaturated Fatty Acids Modulate Dietary Fat Induced Changes in Plasma Lipid and Lipoprotein Profiles? PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2014 PhD Role of Antioxidants in Rhinovirus-Infected Airway Epithelial Cells PhD (Medical Biochemistry), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2014 PhD Association of Dietary Patterns and Macronutrient Intake with Type 2 Diabetes Risk PhD (Nutrition & Dietetics), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2013 PhD Differential Effects of Long Chain Omega-3 Polyunsaturated Fatty Acids on Platelet Aggregation and Hemostatic Variables in Healthy Male Versus Female Subjects PhD (Medical Biochemistry), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2013 PhD Effects of Anti-Inflammatory Bioactives on Diabetes-Induced Changes in Cognition-Related Gene Expression in the Hippocampus PhD (Medical Biochemistry), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2013 PhD Role of Long Chain Omega-3 Polyunsaturated Fatty Acids on Weight Management PhD (Human Physiology), Faculty of Health and Medicine, The University of Newcastle Sole Supervisor
2012 PhD Exploring the Link Between Obesity and Asthma PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2010 PhD Development, Validation and Utilisation of a Food Frequency Questionnaire to Assess the Dietary Intakes of School-aged Children PhD (Nutrition & Dietetics), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2010 PhD Phytosterols and Omega-3 Polyunsaturated Fatty Acids for Cardiovascular Health in Hyperlipidemia PhD (Human Physiology), Faculty of Health and Medicine, The University of Newcastle Sole Supervisor
2009 PhD Omega-3 Fatty Acids, Carotenoids and Inflammation in Endurance-trained Athletes PhD (Human Physiology), Faculty of Health and Medicine, The University of Newcastle Sole Supervisor
2008 PhD Role of Lycopene and Long Chain n-3 Polyunsaturated Fatty Acid Supplements in Airway Inflammation PhD (Human Physiology), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2007 PhD Tomato Serum, Long Chain Omega-3 Fatty Acids and Platelet Aggregation PhD (Nutrition & Dietetics), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2007 PhD A Comparison of High Protein and High Carbohydrate Diets for the Management of Type 2 Diabetes PhD (Nutrition & Dietetics), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2003 PhD Oxidative Stress and Dietary Fat PhD (Nutrition & Dietetics), Faculty of Health and Medicine, The University of Newcastle Sole Supervisor
2003 Masters Nutrition related issues in Paediatric Oncology Patients undergoing Chemotherapy M MedSc (Nutrition & Diet) [R], Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
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News

PhD student Jessica Ferguson and Professor Manohar Garg

Five-pronged approach to diabetes and heart disease

March 20, 2017

Nutrition researchers at the University of Newcastle have five new clinical trials concurrently under recruitment in the Hunter, aiming to combat type 2 diabetes and heart disease with an array of natural dietary supplements and tasty foods.

Rohith Thota

Heart Health Study recruiting people with Type 2 Diabetes

October 28, 2016

Researchers from the University of Newcastle (UON) and John Hunter Hospital are looking for volunteers to take part in a clinical trial which will examine use of curcumin and/or omega-3 fats for lowering cardiovascular disease risk in people with type 2 diabetes.

Fish oil study for blood pressure and brain performance

Fish oil study for blood pressure and brain performance

March 15, 2016

Adults with slightly elevated blood pressure are wanted for a University of Newcastle (UON) clinical trial evaluating the benefits of taking a fish oil supplement for brain health.

Volunteers required to test mental function in type 2 diabetes

Diabetes study testing nutritional approach to delay cognitive decline

January 8, 2015

Researchers in the Clinical Nutrition Research Centre at the University of Newcastle are seeking people with type 2 diabetes to take a new nutritional supplement designed to stimulate blood flow in the brain and reduce the threat of mental impairment.

Prof Manohar Garg

How sweet it is

June 16, 2014

With opinion divided on whether an apple a day really keeps the doctor away, HMRI nutrition researcher Professor Manohar Garg is conducting a new clinical trial to determine the cardio-metabolic health impacts of fructose.

Professor Manohar Garg

Saturated fats to be served in radical nutrition trial

May 16, 2014

Guilt-free servings of butter and white chocolate are on the menu for participants in a revolutionary clinical trial being conducted by HMRI nutrition researcher Professor Manohar Garg.

Professor Manohar Garg

Position

Professor
Nutraceuticals Research
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Focus area

Pharmacy and Experimental Pharmacology

Contact Details

Email manohar.garg@newcastle.edu.au
Phone (02) 4921 5647
Fax (02) 4921 2028

Office

Room MS305C
Building Medical Sciences
Location Callaghan
University Drive
Callaghan, NSW 2308
Australia
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