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Dr Janet Bristow

Conjoint Senior Lecturer

School of Biomedical Sciences and Pharmacy (Human Physiology)

Career Summary

Biography

Dr Holt completed her PhD at the University of Newcastle 2002-2006 investigating gene expression in the developing mammalian ovary. Post-doctoral research areas have included nuclear signalling in the developing mammalian testis and currently, control of meiosis and molecular mechanisms underlying aneuploidy in the mammalian female gamete.

Research Expertise
- Egg quality and the ageing ovary - Meiosis regulation in the male and female gamete - Molecular mechanisms leading to aneuploidy in the egg








Qualifications

  • PhD, University of Newcastle
  • Bachelor of Science (Biotechnology)(Honours), University of Newcastle

Keywords

  • Reproductive Medicine
  • meiosis
  • oocytes

Fields of Research

Code Description Percentage
060199 Biochemistry and Cell Biology not elsewhere classified 50
111499 Paediatrics and Reproductive Medicine not elsewhere classified 50

Professional Experience

Academic appointment

Dates Title Organisation / Department
1/02/2012 - 1/04/2015 Fellow - ARC University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia
1/01/2011 - 1/12/2013 Fellow - UON University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia
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Grants and Funding

Summary

Number of grants 14
Total funding $1,512,387

Click on a grant title below to expand the full details for that specific grant.


20151 grants / $54,698

Nose only inhalation smoke exposure system for mice$54,698

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Phil Hansbro, Laureate Professor Paul Foster, Doctor Jay Horvat, Doctor Janet Bristow, Doctor Malcolm Starkey, Doctor Rebecca Vanders
Scheme Equipment Grant
Role Investigator
Funding Start 2015
Funding Finish 2015
GNo G1501551
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20143 grants / $497,831

miRNA regulation of sperm maturation $396,157

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Brett Nixon, Professor Eileen McLaughlin, Doctor Janet Bristow
Scheme Project Grant
Role Investigator
Funding Start 2014
Funding Finish 2016
GNo G1300125
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

JuLI Stage $71,674

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Pradeep Tanwar, Professor Eileen McLaughlin, Professor Robin Callister, Professor Xu Dong Zhang, Professor Murray Cairns, Professor Brett Nixon, Professor Hubert Hondermarck, Associate Professor Phillip Dickson, Doctor Nikki Verrills, Doctor Matt Dun, Doctor Jessie Sutherland, Doctor Janani Kumar, Doctor Jay Horvat, Doctor Susan Hua, Associate Professor Liz Milward, Associate Professor Estelle Sontag, Professor Dirk Van Helden, Doctor Janet Bristow, Doctor Jean-Marie Sontag
Scheme Equipment Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1500860
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

The Role of the GTPase Dynamin in the Female Germline$30,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Kate Redgrove, Doctor Janet Bristow, Professor Eileen McLaughlin, Professor Brett Nixon
Scheme Bridging Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1301333
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20132 grants / $35,595

The Annual Scientific Meeting of the Endocrine Society of Australia and Society of Reproductive Biology, Sydney 25-28 August 2013.$595

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Janet Bristow
Scheme Travel Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300895
Type Of Funding Internal
Category INTE
UON Y

20122 grants / $759,285

Regulation of germ cell number and quality by Fizzy-Related protein$429,285

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Doctor Janet Bristow
Scheme Discovery Early Career Researcher Award (DECRA)
Role Lead
Funding Start 2012
Funding Finish 2014
GNo G1100556
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

The control of chromosome division during female meiosis$330,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Doctor Janet Bristow
Scheme Discovery Projects
Role Lead
Funding Start 2012
Funding Finish 2014
GNo G1100078
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

20115 grants / $163,478

2010 Research Fellowship - PRCRS (DECRA 1/3/2012)$121,978

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Janet Bristow
Scheme Research Fellowship
Role Lead
Funding Start 2011
Funding Finish 2013
GNo G1100163
Type Of Funding Internal
Category INTE
UON Y

Eppendorf mastercycler pro with thermomixer comfort and 5430R centrifuge$15,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Eileen McLaughlin, Professor Peter Lewis, Professor Adam McCluskey, Conjoint Professor Keith Jones, Professor Brett Nixon, Doctor Shaun Roman, Doctor Jennette Sakoff, Associate Professor Ian Grainge, Doctor Janet Bristow, Doctor Xiao Yang
Scheme Equipment Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1100028
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Mechanisms underlying the incidence of aneuploidy in mammalian eggs$15,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Janet Bristow
Scheme Fellowship Grant
Role Lead
Funding Start 2011
Funding Finish 2011
GNo G1100395
Type Of Funding Internal
Category INTE
UON Y

IMPLEN NanoPhotometer pearl$10,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Murray Cairns, Associate Professor Paul Tooney, Professor Alan Brichta, Emeritus Professor John Rostas, Emeritus Professor Patricia Michie, Conjoint Professor Keith Jones, Professor Ulli Schall, Associate Professor Phillip Dickson, Associate Professor Rohan Walker, Doctor Rick Thorne, Associate Professor Chris Dayas, Doctor Nikki Verrills, Doctor Janet Bristow, Doctor Severine Roselli, Doctor Kathryn Skelding, Doctor Jude Weidenhofer, Associate Professor Liz Milward, Doctor Charles De Bock, Doctor Julie Merriman-Jones, Doctor Jing Qin Wu, Doctor Bing Liu, Dr DAN Johnstone, Ms Belinda Goldie, Doctor Natalie Beveridge
Scheme Equipment Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1100030
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

EMBO Meiosis Meeting, Hotel Ariston and Congress Centre, Cappacio, Italy, 17 - 21 September 2011$1,500

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Janet Bristow
Scheme Travel Grant
Role Lead
Funding Start 2011
Funding Finish 2011
GNo G1100939
Type Of Funding Internal
Category INTE
UON Y

20101 grants / $1,500

Cold Springs Harbor Germ Cell Conference, Cold Spring Harbor Laboratory, NT, USA, 5 - 9 October 2010$1,500

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Janet Bristow
Scheme Travel Grant
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G1000768
Type Of Funding Internal
Category INTE
UON Y
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Research Supervision

Number of supervisions

Completed5
Current3

Total current UON EFTSL

PhD0.3

Current Supervision

Commenced Level of Study Research Title Program Supervisor Type
2015 PhD Levels of Steroids and Endometrial Proteins as an Infertility Indicators Markers in Women with Reproductive Pathologies of Immune Origin. PhD (Medical Biochemistry), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2014 PhD Role of microenvironment in endometrial cancer progression, metastasis and drug resistance PhD (Medical Biochemistry), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2013 PhD Endometrial Stem/Progenitor Cells in Endometrial Regeneration, Carcinogenesis and Aging PhD (Medical Biochemistry), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor

Past Supervision

Year Level of Study Research Title Program Supervisor Type
2017 PhD The Impact of Maternal Ageing and Chemotoxicants on Female Fertility PhD (Biological Sciences), Faculty of Science, The University of Newcastle Principal Supervisor
2015 PhD Susceptibility of Mammalian Oocytes to Chromosome Segregation Errors with Maternal Aging PhD (Human Physiology), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2013 PhD Role of Fzr1 in Embryogenesis PhD (Human Physiology), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2012 PhD Control of Chromosome Segregation in Mouse Oocytes PhD (Human Physiology), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2012 Masters Characterisation of an Oocyte Specific Knockout Model of Cdh1 M Philosophy (Human Physiolog), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
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Dr Janet Bristow

Position

Conjoint Senior Lecturer
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Focus area

Human Physiology

Contact Details

Email janet.holt@newcastle.edu.au

Office

Building Life Sciences Building
Location Callaghan
University Drive
Callaghan, NSW 2308
Australia
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