Dr Ian Van Altena
Honorary Lecturer
School of Environmental and Life Sciences (Chemistry)
- Email:ian.vanaltena@newcastle.edu.au
- Phone:(02) 4921 5480
Career Summary
Biography
Undergraduate: James Cook University, Australia. BSc Chemistry, from 1972. BSc (Hons) with Prof. John Coll 1975
(Post)Graduate: The University of Alberta, Canada. PhD (Chemistry), from 1976, with Prof. William Ayer: Secondary metabolites from fungi
Post-doctoral fellow: The University of British Columbia, Canada, from 1982, with Prof. Raymond Andersen: Siderophores from dinoflagellates
Senior Teaching Fellow: University of Adelaide, Australia, from 1985: Laboratory coordinator. Research: Marine Natural Products Chemistry and chemical ecology
Assistant Lecturer: University of Adelaide, Australia, 1991: Laboratory coordinator, lecturer. Research: Marine Natural Products Chemistry and chemical ecology
Lecturer: The University of Newcastle, Australia, from 1992. Research: Natural Products Chemistry and chemical ecology
Qualifications
- PhD (Chemistry), University of Alberta - Canada
- Bachelor of Science (Honours), James Cook University
- Bachelor of Science, James Cook University
Keywords
- chemical ecology
- compound identification by spectrometry
- environmental chemistry
- general chemistry
- medicinal chemistry
- natural products chemistry
- organic chemistry
Professional Experience
UON Appointment
Title | Organisation / Department |
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Casual Academic | University of Newcastle School of Environmental and Life Sciences Australia |
Academic appointment
Dates | Title | Organisation / Department |
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1/1/1991 - 1/1/1992 | Assistant Lecturer | The University of Adelaide Department of Organic Chemistry Australia |
1/1/1985 - 1/1/1991 | Senior Teaching Fellow | The University of Adelaide Department of Organic Chemistry Australia |
1/6/1982 - 1/6/1984 | Post-Doctoral Fellow | University of British Columbia Department of Oceanography Canada |
Membership
Dates | Title | Organisation / Department |
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Treasurer - Natural Products Group, RACI | Natural Products Group, RACI Australia |
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Member - American Chemical Society | American Chemical Society United States |
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Member - Royal Society of Chemistry | Royal Society of Chemistry Australia |
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Member - Royal Australian Chemical Society | Royal Australian Chemical Society Australia |
Teaching
Code | Course | Role | Duration |
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CHEM2310 |
Organic Chemistry II Faculty of Science and Information Technology, The University of Newcastle | Australia |
lecturer, tutor | 3/3/2002 - 13/12/2016 |
CHEM3310 |
Advanced Organic Synthesis Faculty of Science and Information Technology, The University of Newcastle | Australia |
lecturer, demonstrator | 2/3/2002 - 13/12/2016 |
CHEM1010 |
Introductory Chemistry I Faculty of Science and Information Technology, The University of Newcastle | Australia |
lecturer, coordinator | 2/3/2002 - 13/11/2016 |
CHEM3550 |
Medicinal and Biological Chemistry Faculty of Science and Information Technology,The University of Newcastle |
lecturer, demonstrator | 25/7/2016 - 13/12/2016 |
chem1020 |
Introductory Chemistry II Faculty of Science and Information Technology, The University of Newcastle | Australia |
coordinator | 3/2/2002 - 13/12/2016 |
CHEM2610 |
Environmental Chemistry II Faculty of Science and Information Technology,The University of Newcastle |
lecturer, demonstrator | 2/3/2002 - 13/12/2016 |
CHEM3570 |
Spectroscopic Characterisation of Compounds Faculty of Science and Information Technology,The University of Newcastle |
Lecturer, tutor | 2/3/2002 - 13/12/2015 |
Publications
For publications that are currently unpublished or in-press, details are shown in italics.
Journal article (58 outputs)
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2022 |
Mhd Bakri Y, Holland IP, Motti CA, van Altena IA, 'Steroids of chemophenetic significance from the Australasian brown alga Cystophora xiphocarpa', Biochemical Systematics and Ecology, 101 (2022) [C1] Two new steroids were found upon further chemical investigation of the Australian brown alga Cystophora xiphocarpa. The steroids were identified as (3S,16S,22S,24E)-stigmasta-5,24... [more] Two new steroids were found upon further chemical investigation of the Australian brown alga Cystophora xiphocarpa. The steroids were identified as (3S,16S,22S,24E)-stigmasta-5,24(28)-dien-3,16,22-triol and (3S,16S,22S)-ergosta-5,24(28)-dien-3,16,22-triol. Cystophora xiphocarpa is regarded as the most ancient extant member of its genus and the steroids it produces are biosynthetically related to those identified from C. brownii, which to this point had been the only novel steroids thus far identified from Cystophora spp.
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2021 |
Holland I, Bakri YM, Sakoff J, Zaleta Pinet D, Motti C, van Altena I, 'Bioactive a,ß-conjugated 3-keto-steroids from the Australian brown alga Cystophora xiphocarpa', Phytochemistry, 188 (2021) [C1] As part of our ongoing study of the specialised metabolites present in brown algae belonging to the Cystophora genus, eight new steroids including three pairs of diastereoisomers ... [more] As part of our ongoing study of the specialised metabolites present in brown algae belonging to the Cystophora genus, eight new steroids including three pairs of diastereoisomers were isolated from Cystophora xiphocarpa (Harvey) (Sargassacea, Fucales). The metabolites identified by standard spectrometric methods are (16S,22S)-16,22-dihydroxyergosta-4,24(28)-dien-3-one and (16S,22R)-16,22-dihydroxyergosta-4,24(28)-dien-3-one, (16S,22S,24R)-16,22,24-trihydroxyporifera-4,28-dien-3-one and (16S,22S,24S)-16,22,24-trihydroxystigma-4,28-dien-3-one along with (16S,22S,24E)-16,22-dihydroxystigma-4,24(28)-dien-3-one and (16S,20S)-16,20-dihydroxyergosta-4,24(28)-dien-3-one. (16S,22S,24E)-16,22-Dihydroxystigma-4,24(28)-dien-3-one possessed the most potent cytotoxicity of the steroids in this series with cell growth inhibitions of GI50 8.7 ± 0.7 µM against colon cancer HT29, GI50 5.6 ± 0.8 µM against the breast cancer line MCF-7 and GI50 4.5 ± 0.2 µM against the ovarian cancer cell line A2780. (16S,22R)-16,22-dihydroxyergosta-4,24(28)-dien-3-one was found to be active against the ovarian cancer cell line A2780 with a GI50 of 6.2 ± 0.1 µM.
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2020 |
McBain B, Yardy A, Martin F, Phelan L, van Altena I, McKeowen J, et al., 'Teaching Science Students How to Think', International Journal of Innovation in Science and Mathematics Education, 28 28-35 (2020) [C1] Scientific thinking is more than just critical thinking. Teaching the full range of ways to think like a scientist who practices high quality science is rare. A new core subject i... [more] Scientific thinking is more than just critical thinking. Teaching the full range of ways to think like a scientist who practices high quality science is rare. A new core subject in the Bachelor of Science at the University of Newcastle was developed to allow students to explore six different ways to thinking scientifically through understanding what high-quality science is and contrasting it with poor science and non-science (pseudoscience). Our evaluation indicates that learning about how to think scientifically and be a scientist who practices high quality science is a skill that is valued by and relevant to first year undergraduate students. An evidence-based pedagogy including active learning, participatory learning, student-centred learning, constructive alignment and quality formative and summative feedback to students can support high learning outcomes.
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2020 |
Wood A, Bernhardt PV, van Altena I, Simone MI, 'Crystal structure of 6-azido-6-deoxy-1,2-O-isopropylidene-a-D-glucofuranose', Acta Crystallographica Section E Crystallographic Communications, 76 1653-1656 (2020) [C1]
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2018 |
Dang TT, Bowyer MC, Van Altena IA, Scarlett CJ, 'Comparison of chemical profile and antioxidant properties of the brown algae', INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 53 174-181 (2018) [C1]
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2018 |
Dang TT, Bowyer MC, Van Altena IA, Scarlett CJ, 'Optimum conditions of microwave-assisted extraction for phenolic compounds and antioxidant capacity of the brown alga Sargassum vestitum', SEPARATION SCIENCE AND TECHNOLOGY, 53 1711-1723 (2018) [C1]
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2017 |
Van TN, Vuong QV, Bowyer MC, Van Altena IA, Scarlett CJ, 'MICROWAVE-ASSISTED EXTRACTION FOR SAPONINS AND ANTIOXIDANT CAPACITY FROM XAO TAM PHAN (PARAMIGNYA TRIMERA) ROOT', JOURNAL OF FOOD PROCESSING AND PRESERVATION, 41 (2017) [C1]
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2017 |
Dang TT, Quan VV, Schreider MJ, Bowyer MC, Van Altena IA, Scarlett CJ, 'Optimisation of ultrasound-assisted extraction conditions for phenolic content and antioxidant activities of the alga Hormosira banksii using response surface methodology', JOURNAL OF APPLIED PHYCOLOGY, 29 3161-3173 (2017) [C1]
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2017 |
Bhuyan DJ, Vuong QV, Chalmers AC, van Altena IA, Bowyer MC, Scarlett CJ, 'Development of the ultrasonic conditions as an advanced technique for extraction of phenolic compounds from Eucalyptus robusta', SEPARATION SCIENCE AND TECHNOLOGY, 52 100-112 (2017) [C1]
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2017 |
Nguyen VT, Bowyer MC, Van Altena IA, Scarlett CJ, 'Microwave-assisted extraction as an advanced technique for optimization of saponin yield and antioxidant potential from Phyllanthus amarus', Separation Science and Technology, 52 2721-2731 (2017) [C1]
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2017 |
Perez JDV, Borlagdan MS, Aurigue FB, van Altena IA, Ragasa CY, 'Chemical Constituents of Hoya paziae Kloppenb', RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES, 8 736-739 (2017) [C1]
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2017 |
Borlagdan MS, De Castro MEG, van Altena IA, Ragasa CY, 'Sterols from Trametes versicolor', RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES, 8 740-744 (2017) [C1]
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2017 |
Bhuyan DJ, Sakoff J, Bond DR, Predebon M, Vuong QV, Chalmers AC, et al., 'In vitro anticancer properties of selected Eucalyptus species', IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 53 604-615 (2017) [C1]
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2017 |
Bhuyan DJ, Vuong QV, Bond DR, Chalmers AC, van Altena IA, Bowyer MC, Scarlett CJ, 'Exploring the Least Studied Australian Eucalypt Genera: Corymbia and Angophora for Phytochemicals with Anticancer Activity against Pancreatic Malignancies', CHEMISTRY & BIODIVERSITY, 14 (2017) [C1]
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2017 |
Dang TT, Vuong QV, Schreider MJ, Bowyer MC, Van Altena IA, Scarlett CJ, 'The Effects of Drying on Physico-Chemical Properties and Antioxidant Capacity of the Brown Alga (Hormosira banksii (Turner) Decaisne)', Journal of Food Processing and Preservation, 41 (2017) [C1]
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2017 |
Bhuyan DJ, Vuong QV, Chalmers AC, Bowyer MC, van Altena IA, Scarlett CJ, 'Phytochemical, antibacterial and antifungal properties of an aqueous extract of Eucalyptus microcorys leaves', SOUTH AFRICAN JOURNAL OF BOTANY, 112 180-185 (2017) [C1]
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2016 |
Zaleta-Pinet D, McCluskey A, Hall S, Brophy J, Ashhurst-Smith C, Sakoff J, Van Altena I, 'The Use of the Toxic Plant Myoporum montanum in a Traditional Australian Aboriginal Medicine', Australian Journal of Chemistry, 69 161-168 (2016) [C1] Plants from the family Myoporaceae, which includes the genus Myoporum, are extremely prized by the Australian Aboriginal people for their medicinal properties. Leaves from a plant... [more] Plants from the family Myoporaceae, which includes the genus Myoporum, are extremely prized by the Australian Aboriginal people for their medicinal properties. Leaves from a plant, which was subsequently identified as Myoporum montanum, were provided for chemical investigation by representatives of an Aboriginal community from the Northern Tablelands district of northern New South Wales, Australia. Acetone extraction of the leaves provided a complex mixture of compounds including sesquiterpene hydrocarbons and more polar furanosesquiterpenes, which were identified by gas-liquid chromatography and retention indices (sesquiterpene hydrocarbons) and spectrometric techniques (furanosesquiterpenes). The major compounds found in a water extract were studied for their antibacterial activity using a disc diffusion assay and for their cell growth inhibition activity. The acetone extract contained sesquiterpene hydrocarbons (~30% of the total extract) in which the major compounds were germacrene-D and bicyclogermacrene. In addition, the extract contained five known toxic furanosesquiterpenes: myoporum ketol, (-)-10,11-dehydroisomyodesmone, (+)-10,11-dehydromyodesmone, 10,11-dehydromyoporum ketol, (-)-10,11-dehydromyoporone, and (±)-myoporone. An aqueous extract of the leaves, emulating the medicinal tea used by the Australian Aboriginal community, was found not to contain significant quantities of the sesquiterpene hydrocarbons and the most toxic furanosesquiterpenes. (±)-Myoporone and (-)-10,11-dehydromyoporone remained in the extract as well as a new furanosesquiterpene, 11-hydroxymyoporone. These three compounds were found to have significant antibacterial activity against Staphylococcus epidermidis, Enterococcus faecalis, and Moraxella catarrhalis but low cytotoxicity against a range of cancer cell lines and normal breast cells at 25µM.
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2016 |
Ragasa CY, Tan MCS, De Castro MEG, van Altena IA, 'Chemical constituents of phellinus gilvus (Schwein.) Pat.', Der Pharma Chemica, 8 222-225 (2016) [C1] Chemical investigation of the dichloromethane extract of the fruiting bodies of Phellinus gilvus (Schwein.) Pat. has led to the isolation of ergosterol peroxide (1) and triacylgly... [more] Chemical investigation of the dichloromethane extract of the fruiting bodies of Phellinus gilvus (Schwein.) Pat. has led to the isolation of ergosterol peroxide (1) and triacylglycerols (2). The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy and confirmed by comparison of its 13C NMR data with literature data.
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2016 |
Ragasa CY, Vivar JLA, De Los Reyes MM, van Altena IA, 'Secondary metabolites from Dracontomelon dao (Merr. & Rolfe)', Der Pharma Chemica, 8 257-260 (2016) [C1] The dichloromethane extract of the leaves of Dracontomelon dao (Merr. & Rolfe) has led to the isolation of anacardic acid (1), ß-sitosteryl-3ß-glucopyranoside-6'-O-fatty ... [more] The dichloromethane extract of the leaves of Dracontomelon dao (Merr. & Rolfe) has led to the isolation of anacardic acid (1), ß-sitosteryl-3ß-glucopyranoside-6'-O-fatty acid esters(2), ß-sitosterol (3), phytol (4), a mixture of phytyl fatty acid esters (5) and ß-sitosteryl fatty acid esters (6), chlorophyll a (7), squalene (8),long-chain fatty alcohols (9), and long-chain hydrocarbons (10). The structures of 1-10were identified by comparison of their NMR data with literature data.
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2016 |
Ragasa CY, Macuha MR, De Los Reyes MM, Mandia EH, Van Altena IA, 'Chemical constituents of Ficus septica Burm. F.', International Journal of Pharmaceutical and Clinical Research, 8 1464-1469 (2016) [C1] Chemical investigation of the dichloromethane extracts of Ficus septica Burm.f. led to the isolation of ß-sitosteryl-3ß-glucopyranoside-6¿-O-fatty acid esters (1), a-amyrin fatty ... [more] Chemical investigation of the dichloromethane extracts of Ficus septica Burm.f. led to the isolation of ß-sitosteryl-3ß-glucopyranoside-6¿-O-fatty acid esters (1), a-amyrin fatty acid esters (2), and a mixture of ß-sitosterol (3a) and stigmasterol (3b) in a 5: 2 ratios from the twigs; and 3a, ß-amyrin (4), and long chain saturated fatty alcohols (5) from the leaves. The structures of 1-5 were identified by NMR spectroscopy.
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2016 |
Ragasa CY, Guardamano JD, Tan MCS, Ulep RA, van Altena IA, 'Isolation and structure elucidation of 9-hydroxy-10E, 12Z-octadecadienoic acid from Dioscorea luzonensis', Research Journal of Pharmaceutical, Biological and Chemical Sciences, 7 1233-1236 (2016) [C1] Chemical investigation of the dichloromethane extract of Dioscorea luzonensis Schauer. led to the isolation of 9-hydroxy-10E,12Z-octadecadienoic acid or a-dimorphecolic acid (1) f... [more] Chemical investigation of the dichloromethane extract of Dioscorea luzonensis Schauer. led to the isolation of 9-hydroxy-10E,12Z-octadecadienoic acid or a-dimorphecolic acid (1) from the skin of the tuber. The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy and confirmed by mass spectrometry.
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2016 |
Nguyen VT, Pham NMQ, Vuong QV, Bowyer MC, van Altena IA, Scarlett CJ, 'Phytochemical retention and antioxidant capacity of xao tam phan (Paramignya trimera) root as prepared by different drying methods', Drying Technology, 34 324-334 (2016) [C1] Xao tam phan (Paramignya trimera (Oliv.) Guillaum) has been used as an herbal medicine for the treatment of cancer or cancer-like diseases in recent years, particularly in Vietnam... [more] Xao tam phan (Paramignya trimera (Oliv.) Guillaum) has been used as an herbal medicine for the treatment of cancer or cancer-like diseases in recent years, particularly in Vietnam. Drying is an important step for preparation of dried materials for storage and further investigation; however, the effects of drying must be taken into account when processing samples, because this can have profound effects on the stability of phytochemical compounds and the biological activity of the dried P. trimera root. As such, this study assessed the effects of four different drying methods (conventional, hot air, vacuum, and microwave) on phytochemical retention and antioxidant capacity of P. trimera root, to identify an optimal drying method for P. trimera root. The results showed that the drying methods significantly affected phytochemical levels and antioxidant capacity of P. trimera root and that among the four drying methods tested, microwave drying (400¿W) had the highest levels of phytochemical compounds, with total phenolic, total flavonoid, proanthocyanidin, and saponin contents of 11.27¿mg GAE, 19.88¿mg RE, 3.98¿mg CE, and 267.15¿mg EE/gram of dried sample, respectively. Dried sample prepared using this method had antioxidant capacity comparable to that of other drying methods. In addition, this method had the shortest drying time (0.28¿h) and consumed the least energy (0.28¿kWh). Therefore, microwave drying should be considered for drying P. trimera root for further investigation and utilization.
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2016 |
Nguyen VT, Bowyer MC, Van Altena IA, Scarlett CJ, 'Optimisation of microwave-assisted extraction from Phyllanthus amarus for phenolic compounds-enriched extracts and antioxidant capacity', CHEMICAL PAPERS, 70 713-725 (2016) [C1]
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2016 |
Ragasa CY, Batarra TC, Tan MCS, van Altena IA, 'Chemical constituents of Alstonia scholaris (L.) R. Br', Der Pharma Chemica, 8 193-196 (2016) [C1] Chemical investigation of the dichloromethane extract of the leaves of Alstonia scholaris (L.) R. Br. has yielded mixtures of erythrodiol (1a), uvaol (1b), and betulin (1c) in a 1... [more] Chemical investigation of the dichloromethane extract of the leaves of Alstonia scholaris (L.) R. Br. has yielded mixtures of erythrodiol (1a), uvaol (1b), and betulin (1c) in a 1:1:1 ratio, oleanolic acid and ursolic acid in a 2:1 ratio, ß-amyrin acetate (3b) and a-amyrin acetate (3b) in a 1:4 ratio, and ß-sitosterol (4a) and stigmasterol (4b) in a 3:2 ratio; squalene (5), ß-sitosteryl-3ß-glucopyranoside-6 's -O-fatty acid esters (6), and chlorophyll a (7). The structures of 1-7 were identified by comparison of their NMR data with literature data.
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2016 |
Apostol PG, De Los Reyes MM, Van Altena IA, Ragasa CY, 'Chemical constituents of Melanolepis multiglandulosa (Reinw. Ex blume)', International Journal of Pharmaceutical and Clinical Research, 8 1663-1665 (2016) [C1] Chemical investigation of the dichloromethane extracts of Melanolepis multiglandulosa (Reinw. ex Blume) yielded taraxeryl fatty acid esters (1), squalene (2), (E)-3-alkenoic acids... [more] Chemical investigation of the dichloromethane extracts of Melanolepis multiglandulosa (Reinw. ex Blume) yielded taraxeryl fatty acid esters (1), squalene (2), (E)-3-alkenoic acids (3), ß-carotene (4), a mixture of ß-sitosterol (5a) and stigmasterol (5b), long-chain fatty alcohols (6), and long-chain hydrocarbons (7) from the leaves; and 7, triacylglycerols (8), and long-chain saturated fatty acid esters (9) from the twigs. The structures of 1-9 were identified by comparison of their NMR data with literature data. |
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2016 |
Borlagdan M, Aurigue FB, Van Altena IA, Ragasa CY, 'Triterpenes from Hoya paziae Kloppenb', Pharmacognosy Journal, 8 487-489 (2016) [C1] Chemical investigation of the dichloromethane extracts of the stems of Hoya paziae Kloppenb. led to the isolation of taraxerol (1), taraxeryl acetate (2), and a mixture ?-amyrin a... [more] Chemical investigation of the dichloromethane extracts of the stems of Hoya paziae Kloppenb. led to the isolation of taraxerol (1), taraxeryl acetate (2), and a mixture ?-amyrin acetate (3), and ß-amyrin acetate (4) in about 2.5:1 ratio. The structures of 1-4 were identified by comparison of their NMR data with those reported in the literature.
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2016 |
Van TN, Hong NTP, Bowyer MC, van Altena IA, Scarlett CJ, 'Influence of solvents and novel extraction methods on bioactive compounds and antioxidant capacity of Phyllanthus amarus', CHEMICAL PAPERS, 70 556-566 (2016) [C1]
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2016 |
Bhuyan D, Vuong QV, Chalmers A, van Altena I, Bowyer M, Scarlett C, 'Investigation of phytochemicals and antioxidant capacity of selected Eucalyptus species using conventional extraction', Chemical Papers, 70 567-575 (2016) [C1]
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2016 | Alimboyoguen AB, Cruz-De Castro KA, Van Altena IA, Ragasa CY, 'Triterpenes from Pittosporum resiniferum hemsl', International Journal of Toxicological and Pharmacological Research, 8 261-262 (2016) [C1] | Nova | |||||||||
2015 |
Nguyen VT, Bowyer MC, Vuong QV, Altena IAV, Scarlett CJ, 'Phytochemicals and antioxidant capacity of Xao tam phan (Paramignya trimera) root as affected by various solvents and extraction methods', Industrial Crops and Products, 67 192-200 (2015) [C1] Xao tam phan (. Paramignya trimera (Oliv.) Guillaum) is a Vietnamese traditionally medicinal plant used in the treatment of numerous cancers. The preparation of Xao tam phan extra... [more] Xao tam phan (. Paramignya trimera (Oliv.) Guillaum) is a Vietnamese traditionally medicinal plant used in the treatment of numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This study aimed to investigate the effects of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the greatest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (except for total flavonoids) and antioxidant capacity, when compared to conventional and ultrasound-assisted extractions. These data reveal that the use of methanol and microwave-assisted extraction are recommended for extraction of biologically active phytochemicals from P. trimera root for application in the nutraceutical and/or pharmaceutical industries.
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2015 |
Bhuyan DJ, Quan VV, Chalmers AC, van Altena IA, Bowyer MC, Scarlett CJ, 'Microwave-assisted extraction of Eucalyptus robusta leaf for the optimal yield of total phenolic compounds', INDUSTRIAL CROPS AND PRODUCTS, 69 290-299 (2015) [C1]
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2015 |
Nguyen VT, Vuong QV, Bowyer MC, Altena IAV, Scarlett CJ, 'Effects of Different Drying Methods on Bioactive Compound Yield and Antioxidant Capacity of Phyllanthus amarus', Drying Technology, 33 1006-1017 (2015) [C1]
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2014 |
Zaleta-Pinet DA, Holland IP, Muñoz-Ochoa M, Murillo-Alvarez JI, Sakoff JA, van Altena IA, McCluskey A, 'Cytotoxic compounds from Laurencia pacifica.', Org Med Chem Lett, 4 8 (2014)
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2014 |
Erwin, Noor A, Soekamto NH, van Altena I, Syah YM, 'Waltherione C and cleomiscosin from Melochia umbellata var. Degrabrata K. (Malvaceae), biosynthetic and chemotaxonomic significance', Biochemical Systematics and Ecology, 55 358-361 (2014)
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2012 |
Ridhay A, Noor A, Soekamto NH, Harlim T, van Altena I, 'A stigmasterol glycoside from the root wood of Melochia umbellata (Houtt) Stapf Var. degrabrata K.', Indonesian Journal of Chemistry, 12 100-103 (2012) A stigmasterol glycoside (stigmast-5,22-dien-3-O-ß-D-glucopyranoside) has been isolated from the chloroform fraction of root wood of Melochia umbellata (Houtt) Stapf var. degrabra... [more] A stigmasterol glycoside (stigmast-5,22-dien-3-O-ß-D-glucopyranoside) has been isolated from the chloroform fraction of root wood of Melochia umbellata (Houtt) Stapf var. degrabrata K. The compound structure was determined on spectroscopic evidences including IR, 1D and 2D NMR and compared to previous data. The isolate was also active against Aspergillus niger.
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2010 |
Laird DW, Bennett S, Bian B, Sauer B, Wright K, Hughes V, Van Altena IA, 'Chemical investigation of seven Australasian Cystophora species: New chemistry and taxonomic insights', Biochemical Systematics and Ecology, 38 187-194 (2010) [C1]
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2009 |
McCann N, Phan DT, Attalla M, Puxty G, Fernandes D, Conway WO, et al., 'Molecular interactions between amine and carbonate species in aqueous solution: Kinetics and thermodynamics', Energy Procedia, 1 995-1002 (2009) [C1]
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2009 |
Holland IP, McCluskey A, Sakoff JA, Gilbert J, Chau N, Robinson PJ, et al., 'Steroids from an Australian Sponge Psammoclema sp', Journal of Natural Products, 72 102-106 (2009) [C1]
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2007 |
Laird DW, Poole R, Wikstrom M, Van Altena IA, 'Pycnanthuquinone C, an unusual 6,6,5-tricyclic geranyltoluquinone from the Western Australian brown alga Cystophora harveyi', Journal of Natural Products, 70 671-674 (2007) [C1]
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2006 |
Laird DW, Van Altena IA, 'Tetraprenyltoluquinols from the brown alga Cystophora fibrosa', Phytochemistry, 67 944-955 (2006) [C1]
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2006 |
Koysomboon S, Van Altena IA, Kato S, Chantrapromma K, 'Antimycobacterial flavonoids from Derris indica', Phytochemistry, 67 1034-1040 (2006) [C1]
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2003 |
Van Altena IA, Van Soest R, Roberge M, Andersen RJ, 'Trisphaerolide A, a Novel Polyketide from the Dominican Sponge Erylus trisphaerus', Journal of Natural Products, 561-563 (2003) [C1]
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1999 |
Van Altena IA, Butler AJ, Dunne SJ, 'A new cyclized 9,11-secosterol enol-ether from the Australian sponge Euryspongia arenaria', Journal of Natural Products, 62 1154-1157 (1999) [C1]
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1998 |
Bian B, Van Altena IA, 'Four New Compounds from the Australian Brown Alga Cystophora brownii', Australian Journal of Chemistry, 51 1157-1165 (1998) [C1]
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Show 55 more journal articles |
Conference (4 outputs)
Year | Citation | Altmetrics | Link | ||||||||
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2019 |
McBain V, Yardy A, Frances M, Tose H, Phelan L, Van Altena I, et al., 'Avoiding the science stupidity trap', Proceedings of the Australian Conference on Science and Mathematics Education, The University of Sydney and University of Technology, Sydney (2019) [E1]
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Nova | |||||||||
2018 |
Nguyen VT, Van Vuong Q, Bowyer MC, Van Altena IA, Scarlett CJ, 'The effects of different drying methods on bioactive compound yield and antioxidant capacity of Phyllanthus amarus', Acta Horticulturae, Ho Chi Minh City, Vietnam (2018) [E1]
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Nova | |||||||||
2015 |
Bond D, Turner A, Richmond R, Sadeqzadeh E, Vuong Q, Bhuyan D, et al., 'THE SEARCH FOR NOVEL TREATMENT AGENTS FOR PANCREATIC CANCER: TALES FROM THE LAND AND SEA', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2015) [E3]
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2014 |
Sadeqzadeh E, Vuong QV, Goldsmith CD, Nguyen VT, Bhuyan DJ, Trung TD, et al., 'A NATURAL PRODUCT DRUG DISCOVERY PIPELINE FOR NOVEL PANCREATIC CANCER THERAPIES: A NEW CANCER RESEARCH HUB FOR THE HUNTER REGION OF NSW', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2014) [E3]
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Show 1 more conference |
Grants and Funding
Summary
Number of grants | 3 |
---|---|
Total funding | $202,778 |
Click on a grant title below to expand the full details for that specific grant.
19951 grants / $4,778
Computer Screen Projection in Small Classes. Applications in 3rd Year Chemometrics, 2nd Year Analytical Chemistry and 3rd Year Organic Chemistry Classes$4,778
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Emeritus Professor Marcel Maeder, Doctor Ian Van Altena |
Scheme | Teaching Committee Teaching Grants |
Role | Investigator |
Funding Start | 1995 |
Funding Finish | 1995 |
GNo | G0175880 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
19942 grants / $198,000
94 MECH C. High field NMR facilities$190,000
Funding body: Department of Education, Training & Youth Affairs
Funding body | Department of Education, Training & Youth Affairs |
---|---|
Project Team | Doctor Ian Van Altena |
Scheme | Mechanism C Infrastructure |
Role | Lead |
Funding Start | 1994 |
Funding Finish | 1994 |
GNo | G0174400 |
Type Of Funding | Scheme excluded from IGS |
Category | EXCL |
UON | Y |
Identification of Novel Compounds from Marine Algae$8,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Doctor Ian Van Altena |
Scheme | Project Grant |
Role | Lead |
Funding Start | 1994 |
Funding Finish | 1994 |
GNo | G0174782 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Research Supervision
Number of supervisions
Current Supervision
Commenced | Level of Study | Research Title | Program | Supervisor Type |
---|---|---|---|---|
2006 | PhD | Natural Products as a Source for Dynamin Inhibitors | Chem Sc Not Elsewhere Classifd, University of Newcastle | Co-Supervisor |
2005 | PhD | Marine Natural Products | Chem Sc Not Elsewhere Classifd, University of Newcastle | Co-Supervisor |
Past Supervision
Year | Level of Study | Research Title | Program | Supervisor Type |
---|---|---|---|---|
2018 | PhD | Brown Algae as a Source of Bioactive Compounds for Pancreatic Cancer Treatment | PhD (Food Science), College of Engineering, Science and Environment, The University of Newcastle | Co-Supervisor |
2018 | PhD | Bioactive Compounds, Antioxidant and Cytotoxic Capacities of Two Vietnamese Medicinal Plants: Phyllanthus Amarus and Paramignya Trimera | PhD (Food Science), College of Engineering, Science and Environment, The University of Newcastle | Co-Supervisor |
2018 | PhD | Phytochemicals Derived from Australian Eucalypts as Anticancer Agents for Pancreatic Malignancies | PhD (Food Science), College of Engineering, Science and Environment, The University of Newcastle | Co-Supervisor |
2015 | PhD | Studies in Marine Natural Products. 1. Dynamin 1 Screening of Sponges from Catherine Hill Bay. 2. Chemistry of Cystophora Xiphocarpa. 3. Investigation of "Paua Greening" of Haliotis Iris from New Zealand's Cook Strait | PhD (Chemistry), College of Engineering, Science and Environment, The University of Newcastle | Principal Supervisor |
2014 | PhD | Drugs from Nature: 1. Dynamin I Inhibitors from Mexican Marine Algae; 2. Chemical Investigation of an Australian Aboriginal Traditional Remedy | PhD (Chemistry), College of Engineering, Science and Environment, The University of Newcastle | Principal Supervisor |
2012 | PhD | 1. Dynamin-l Inhibitors from Sessile Marine Invertebrates; 2. Chemotaxonomy of Cystophora spp. | PhD (Chemistry), College of Engineering, Science and Environment, The University of Newcastle | Co-Supervisor |
2012 | PhD | Marine Natural Products and Brown Macroalga Cystophora Moniliformis Chemistry | PhD (Chemistry), College of Engineering, Science and Environment, The University of Newcastle | Principal Supervisor |
2012 | PhD | Disruption of Clathrin Mediated-Endocytosis through Small Molecule Inhibition of Dynamin and Clathrin | PhD (Chemistry), College of Engineering, Science and Environment, The University of Newcastle | Co-Supervisor |
2011 | Masters | Novel Inhibitors of Clathrin Mediated Endocytosis | M Philosophy (Chemistry), College of Engineering, Science and Environment, The University of Newcastle | Co-Supervisor |
2009 | PhD | Norcantharidin Analogues: PP1 and PP2A Inhibition and Potential Therapeutic Development | PhD (Chemistry), College of Engineering, Science and Environment, The University of Newcastle | Co-Supervisor |
2005 | PhD | Chemotaxonomy of the brown algal genus Cyclophoria | PhD (Chemistry), College of Engineering, Science and Environment, The University of Newcastle | Principal Supervisor |
News
News • 4 Oct 2018
Study reveals which cup of coffee delivers the biggest caffeine kick
An Australian study investigating five popular types of coffee brewing methods has found that espresso contains the highest concentration of caffeine.
Dr Ian Van Altena
Positions
Honorary Lecturer
School of Environmental and Life Sciences
College of Engineering, Science and Environment
Casual Academic
School of Environmental and Life Sciences
College of Engineering, Science and Environment
Focus area
Chemistry
Contact Details
ian.vanaltena@newcastle.edu.au | |
Phone | (02) 4921 5480 |
Fax | (02) 4921 5472 |
Link | Personal webpage |
Office
Room | enter via C228 |
---|---|
Building | Chemistry Building |
Location | Callaghan University Drive Callaghan, NSW 2308 Australia |