Miss Helen Fairlamb
School of Nursing and Midwifery
- Phone:02 4349 4411
Responsible for the project management of a research study investigating the efficacy of normalistaion of Advanced Care Planning (ACP) for people with chronic diseases (in both acute and community settings).
A background in microbiology and clinical research into infectious diseases and gastroenterological conditions. Experience in research design, screening for suitable research participants, involving participants in health research (including the informed consent process), data collection and analysis (primarily quantitative research methods) and managing and monitoring clinical research projects.
An interest in the interplay between human and environmental health; the 'One Health' principle and in the microbiome and its potential modulation / role in health management.
- Postgraduate Certificate in Clinical Research, Lancaster University - England
- Bachelor of Science (Honours), University of York (UK)
- Clinical Research
- Infectious Diseases
- Project Management
- Experimental design
- Zoonotic pathogens
- English (Mother)
Fields of Research
|110399||Clinical Sciences not elsewhere classified||50|
|111099||Nursing not elsewhere classified||50|
|Dates||Title||Organisation / Department|
|23/10/2017 -||Research Project Manager - 'ACP in chronic conditions' Project||Faculty of Health and Medicine, University of Newcastle
School of Nursing and Midwifery
|6/03/2017 - 27/07/2018||Clinical Research Practitioner||Cumbria Partnership NHS Foundation Trust
Clinical Research department
|6/08/2012 - 27/10/2017||Research Practitioner||North Cumbria University Hospitals NHS Trust
Research & Development department
|6/02/2012 - 3/08/2012||Microbiologist||North Cumbria University Hospitals NHS Trust | United Kingdom
|7/11/2011 - 23/02/2018||Wildlife Health Research Intern||Wildlife & Wetlands Trust (WWT)
|8/09/2008 - 28/10/2011||Research Project Manager||Rawwater Engineering Company Ltd.
|3/09/2007 - 5/09/2008||Research assistant / microbiologist||Thames Water Utilities Ltd
Research & Development department - Clean Water services
For publications that are currently unpublished or in-press, details are shown in italics.
Journal article (4 outputs)
Forbes M, Fairlamb H, Jonker L, 'Impact of patient-held record on knowledge at 1-year follow-up for glaucoma patients: Single-center randomized controlled trial', European Journal of Ophthalmology, 27 542-547 (2017)
© 2017 Wichtig Publishing. Purpose: To assess whether provision of a personalized patient-held eye health summary (glaucoma personal record) improves patients¿ knowledge of glauco... [more]
© 2017 Wichtig Publishing. Purpose: To assess whether provision of a personalized patient-held eye health summary (glaucoma personal record) improves patients¿ knowledge of glaucoma at 1-year follow-up. The National Institute for Clinical Excellence has recommended such an approach to ascertain if this may ultimately help slow disease progression. Methods: Recruited patients, newly diagnosed with glaucoma conditions, were randomly allocated to receive standard clinical care or an additional glaucoma personal record, detailing the current state of each individual¿s eye condition. Mann-Whitney U test was applied for comparison of knowledge scores between groups at 1-year follow-up, using a validated questionnaire. Multiple linear regression analysis was applied to detect any factors significantly associated with a difference in glaucoma knowledge. Results: A total of 122 patients were recruited; 57 controls and 44 intervention patients were tested for their glaucoma knowledge, equating to 83% retention rate. Out of a maximum available 100% converted score, the median scores were 58% and 53% for the control and intervention arm, respectively (p = 0.85). Regression analysis showed that age (p = 0.015) had a negative association and level of education (p = 0.002) had a positive association with glaucoma knowledge. Conclusions: The glaucoma personal record does not impact on a patient¿s knowledge of glaucoma in either a positive or negative way. Other approaches to improve health literacy among glaucoma patients, particularly for patients who are elderly or have a limited educational background, must be considered to improve patients¿ awareness and knowledge of their own condition. Trial registration: International Standard Randomized Controlled Trial Number Registry: ISRCTN41306818.
Carbone M, Sharp SJ, Flack S, Paximadas D, Spiess K, Adgey C, et al., 'The UK-PBC Risk Scores: Derivation and Validation of a Scoring System for Long-Term Prediction of End-Stage Liver Disease in Primary Biliary Cholangitis', HEPATOLOGY, 63 930-950 (2016)
Forbes M, Fairlamb H, Jonker L, 'The Health Of Patients' Eyes (HOPE) Glaucoma study. The effectiveness of a 'glaucoma personal record' for newly diagnosed glaucoma patients: Study protocol for a randomised controlled trial', Trials, 16 (2015)
© 2015 Forbes et al. Background: Glaucoma involves progressive optic nerve fibre loss, subsequently leading to irreversible and disabling visual field defects. In Europe, the prev... [more]
© 2015 Forbes et al. Background: Glaucoma involves progressive optic nerve fibre loss, subsequently leading to irreversible and disabling visual field defects. In Europe, the prevalence of glaucoma is approximately 2.2 % of all people aged over 40 years; this equates to 12 million people. Glaucoma patients require regular lifelong follow-up, contributing to a large financial and resource burden for the National Health Service (NHS) in the UK. This study aims to determine whether providing newly diagnosed glaucoma patients with a personalised client-held eye health summary ('glaucoma personal record'), improves patients' knowledge of their glaucoma condition. A potential long-term benefit could be improved self-management and henceforth a slower rate of deterioration. Methods/Design: HOPE Glaucoma is a 3-year, prospective, parallel-group, pragmatic, single-centred, randomised controlled trial. An anticipated 122 adults, newly diagnosed with glaucoma (including ocular hypertension, suspected glaucoma and/or chronic open-angle glaucoma) will be recruited from a nurse-led ophthalmology outpatient clinic at a medium-sized NHS Trust. Participants will be randomly allocated to receive standard clinical care (control arm) or standard care plus a glaucoma personal record, detailing the current state of their condition (interventional arm). Participant assessments are designed to test whether provision of a glaucoma personal record 1) improves patient knowledge of glaucoma and 2) contributes to improvements in clinical outcomes, i.e. delay of visual field loss. The primary outcome measure is better client knowledge of glaucoma at the 9-12 month follow-up visit. Secondary outcome measures include the rate of visual field loss and patient-reported outcome measures on visual function (National Eye Institute VFQ - 25) measured at baseline, 9-12 months, 24 months and 36 months. Estimating a 20 % drop-out rate, the study will have 90 % power to detect a mean two-point difference in glaucoma knowledge score between groups at 5 % significance - based on two-sided Mann-Whitney U test. Discussion: If a glaucoma personal record is found to significantly improve glaucoma patients' knowledge of their condition, this intervention could potentially provide a low-cost, straightforward tool to educate and engage glaucoma patients. Subsequently, this could have the potential to increase patient self-management and therefore allow glaucoma patients to prolong their sight functionality for longer.
Cordell HJ, Han Y, Mells GF, Li Y, Hirschfield GM, Greene CS, et al., 'International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways', Nature Communications, 6 (2015)
© 2015 Macmillan Publishers Limited. All rights reserved. Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is l... [more]
© 2015 Macmillan Publishers Limited. All rights reserved. Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in an independent cohort (n=3,716 cases and 4,261 controls). We discover and validate six previously unknown risk loci for PBC (P combined < 5 × 10 -8 ) and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine-cytokine pathways, for which relevant therapies exist.
|Show 1 more journal article|
Report (1 outputs)
|2012||Cromie R, Lee R, Delahay JL, Newth JL, Fairlamb HA, Reeves JP, et al., 'Ramsar Wetland Disease Manual: Guidelines for Assessment, Monitoring and Management of Animal Disease in Wetlands. Ramsar Technical Report No. Ramsar Convention Secretariat, Gland, Switzerland.', Secretariat of the Ramsar Convention on Wetlands (Ramsar, Iran, 1971)., 321 (2012)|
Miss Helen Fairlamb
Faculty of Health, School of Nursing & Midwifery
School of Nursing and Midwifery
Faculty of Health and Medicine
|Phone||02 4349 4411|
|Fax||+61 2 4349 4538|
|Building||Busines & Investment Centre of Excellence|
10 Chittaway Road
Ourimbah, NSW 2258