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Professor Adam McCluskey

Professor

School of Environmental and Life Sciences (Chemistry)

Driving the Therapeutic Drug Revolution

Professor Adam McCluskey has been a driving force behind the establishment of the Centre for Kinomics, a world-first research facility.

Professor Adam McCluskey

McCluskey has established the Centre in collaboration with respected neurobiologist Professor Phil Robinson, of the Children's Medical Research Institute (CMRI) at Westmead.

The Centre is named for a biological process called phosphorylation that is mediated by kinases, hence 'kinomics', and which controls the activation of many signalling and enzymatic proteins.

The Centre, which has laboratories at the University of Newcastle and CMRI, has been funded by a $1 million prize from the Ramaciotti Foundation and a $3.1 million grant from the Australian Cancer Research Foundation for the study of protein kinases and the drugs that target them.

The Centre's focus is designing next­ generation drugs for epilepsy, cancer and neuropathic pain. So far the focus has been epilepsy, a disorder where one in three sufferers gain no relief from existing treatments. The goal is creating drugs that do not have the often­ debilitating side effects.

The emerging field revolves around the 518 protein kinases in the body, which are the key signalling proteins behind biological functions. If they malfunction then the body malfunctions.

Pharmaceutical companies invest billions of dollars in research to develop kinase inhibitors.

"It's a crude analogy," says McCluskey, "but in drug design there is the lock and the key. You either want to lock or unlock the protein action and the drug is the key that will enable you to do that."

Using unique equipment costing hundreds of thousands of dollars, the researchers are able to quickly pinpoint the undesirable elements of existing therapeutic drugs.

"We can identify the range of proteins a drug interacts with and look out for red flags," explains McCluskey, a chemist. "There are some proteins you would never want a drug to touch because of the serious, even deadly, side effects."

The Centre is extending a 2007 discovery by a private German drug company that involves a new technique for analysing interactions between kinase inhibitors and hundreds of proteins at a time. The technology is known as Kinobeads and it fast tracks what has been until now a time-consuming process.

Mass spectrometry determines what proteins have been singled out by the Kinobeads, indicating which kinases have remained bound to the drug in question. The process would normally take at least six months but the Centre's cutting-edge technology will reduce it to a few days.

There are 23 research groups around the world waiting for the Centre to produce its first batch of beads. This technology gives us the ability to rapidly enhance our potential to test and manufacture pharmaceuticals that will benefit many individuals suffering from a range of disorders.

Professor McCluskey's research is conducted in collaboration with the Hunter Medical Research Institute's (HMRI) Cancer Research Program. His research is supported by grants from HMRI.

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Professor Adam McCluskey

Driving the Therapeutic Drug Revolution

Professor Adam McCluskey has been the driving force behind the establishment of the Centre for Kinomics, a world-first research facility in collaboration with r

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Career Summary

Biography

I am a (BScHons and PhD) graduate in chemistry of the University of Strathclyde, Scotland.

Principle Roles at UON

I am a teaching and research active academic who believes that nurturing students and introducing a positive research experience is one of the pillars of teaching at the University of Newcastle.

Research Expertise
My primary area of resaerch is in the medicinal chemistry / chemical biology space where my main focus is in the development of tool compounds, and drugs, targeting endocytosis.  The potential outcomes of our research include (but are not limited to) the development of new synthetic methodologies; the development of new drugs & the development of new tools for dissecting signal transduction pathways.

This led to the establishment of the dynamin modulators platform of which I am team leader (chemistry). This team interacts with, and supplies the only known endocytosis inhibitors to research teams worldwide (UK, USA, Germany, Denmark etc). I am also an integral component of the development of new anti-epileptic drugs alongside the National Institute of Health, National Institute of Neurological Disorders and Stroke (Bethesda USA).

I head the chemistry component of the Australian Cancer Research Foundation (supported by Ramaciotti) Centre for Kinomics (CFK), a new approach for direct profiling of cellular kinases, a multi-million dollar initiative providing a unique service to multiple research teams throughout Australia. Kinases are the cancer drug target of the 21st century. The CFK offers a unique opportunity to profile biological probes (drugs) and cellular kinases to identify new therapeutic targets, new uses for old drugs and rapid IC50 determination of individual compounds against the entire cellular kinome (cellular complement of protein kinases). The CFK at the University of Newcastle has established one of the first fully equipped flow chemistry laboratories in Australia.


Qualifications

  • PhD, University of Strathclyde
  • Bachelor of Science (Honours), University of Strathclyde

Keywords

  • Anti-cancer agents
  • Chemical Biology
  • Clathrin Inhibitors
  • Drug Design and Discovery
  • Dynamin GTPase
  • Flow Chemistry
  • Organic Chemistry

Fields of Research

Code Description Percentage
030401 Biologically Active Molecules 60
030503 Organic Chemical Synthesis 40

Professional Experience

UON Appointment

Title Organisation / Department
Professor University of Newcastle
School of Environmental and Life Sciences
Australia

Academic appointment

Dates Title Organisation / Department
1/01/2010 -  Honorary Scientist

Chemical Biology

The University of Sydney
Children's Medical Research Institute
Australia
1/12/1995 -  Associate Professor in Chemistry University of Newcastle
Faculty of Science
Australia

Awards

Recognition

Year Award
2005 Vice Chancellors Award for Teaching Excellence, Science & IT
University of Newcastle
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Grants and Funding

Summary

Number of grants 102
Total funding $18,918,722

Click on a grant title below to expand the full details for that specific grant.


20171 grants / $9,884

New and effective drugs for the treatment of giardial infections$9,884

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Linkage Pilot Research Grant
Role Lead
Funding Start 2017
Funding Finish 2018
GNo G1701191
Type Of Funding Internal
Category INTE
UON Y

20161 grants / $1,205,611

A new approach to treating intractable epilepsy$1,205,611

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Adam McCluskey, Prof Phillip Robinson, Dr Nigel Jones
Scheme Project Grant
Role Lead
Funding Start 2016
Funding Finish 2019
GNo G1500279
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

20152 grants / $140,000

Characterisation of a new class of antimicrobial agent for multidrug-resistant infections$120,000

Funding body: Neoculi Pty Ltd

Funding body Neoculi Pty Ltd
Project Team Professor Adam McCluskey
Scheme Research Project
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1500895
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

The development of new drugs that selectively target breast cancer$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Jennette Sakoff, Professor Adam McCluskey
Scheme Project Grant
Role Investigator
Funding Start 2015
Funding Finish 2015
GNo G1501381
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20146 grants / $1,358,214

Dual purpose contraception $681,381

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Laureate Professor John Aitken, Professor Adam McCluskey, Professor Kenneth Beagley
Scheme Project Grant
Role Investigator
Funding Start 2014
Funding Finish 2016
GNo G1300304
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Pushing The Boundaries Of Flow Chemistry - Towards New Anti-Viral Agents$461,634

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Adam McCluskey, Professor Volker Haucke
Scheme Discovery Projects
Role Lead
Funding Start 2014
Funding Finish 2016
GNo G1300160
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Visualisation of microparticles for development of biomarkers and targeted drug delivery mechanisms$125,199

Funding body: Cancer Institute NSW

Funding body Cancer Institute NSW
Project Team Associate Professor Christopher Scarlett, Doctor Kathryn Skelding, Doctor Jude Weidenhofer, Doctor Matt Dun, Doctor Kelly Kiejda, Professor Adam McCluskey, Ms Elham Sadeqzadeh, Professor Hubert Hondermarck, Doctor Rick Thorne, Laureate Professor Rodney Scott
Scheme Research Equipment Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1400627
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Characterisation of a new class of antimicrobial agent for multidrug-resistant infections$45,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Dr Darren Trott, Professor Adam McCluskey, Mr Stephen Page
Scheme Linkage Projects
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1401198
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Enhancing radiation effects for the treatment of brain cancer $25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Jennette Sakoff, Dr JAYNE Gilbert, Professor Adam McCluskey
Scheme Project Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1301412
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

The role of dynamin is spermatogenesis and sperm-oocyte interactions$20,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Brett Nixon, Professor Eileen McLaughlin, Professor Adam McCluskey
Scheme Near Miss Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1301400
Type Of Funding Internal
Category INTE
UON Y

201310 grants / $564,141

Advanced Stopped Flow - Electron Paramagnetic Resonance Apparatus for Measurement of Short-Lived Free Radicals in Engineering, Science and Medicine$180,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Conjoint Professor Bogdan Dlugogorski, Professor Adam McCluskey, Laureate Professor John Aitken, Professor Paul Dastoor, Professor Scott Donne
Scheme Linkage Infrastructure Equipment & Facilities (LIEF)
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1200569
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

Advanced Stopped Flow - Electron Paramagnetic Resonance Apparatus for Measurement of Short-Lived Free Radicals in Engineering, Science and Medicine$175,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Conjoint Professor Bogdan Dlugogorski, Laureate Professor John Aitken, Professor Paul Dastoor, Professor Scott Donne, Professor Adam McCluskey
Scheme Equipment Grant
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1200186
Type Of Funding Internal
Category INTE
UON Y

Multi-Centre Screening and Development Platform for Pre-Clinical Drugs for Glioblastoma$101,612

Funding body: Cancer Council NSW

Funding body Cancer Council NSW
Project Team Prof Phillip Robinson, Ms Megan Chircop, Professor Roger Reddel, Professor Adam McCluskey, Dr Jennette Sakoff
Scheme Research Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300989
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Central Contribution to Faculty Peer Review - FSIT$33,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Special Project Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1301330
Type Of Funding Internal
Category INTE
UON Y

New Drugs to Kill Superbugs$13,000

Funding body: University of Newcastle - Faculty of Science & IT

Funding body University of Newcastle - Faculty of Science & IT
Project Team Professor Peter Lewis, Professor Adam McCluskey, Doctor Chris Gordon, Doctor Joey Ambrus
Scheme Strategic Small Grant
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1401065
Type Of Funding Internal
Category INTE
UON Y

Dynamin - role in sperm oocyte interaction$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Eileen McLaughlin, Professor Brett Nixon, Professor Adam McCluskey
Scheme Near Miss Grant
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1300483
Type Of Funding Internal
Category INTE
UON Y

Dynamin - role in sperm oocyte interaction$10,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Eileen McLaughlin, Professor Brett Nixon, Professor Adam McCluskey
Scheme Near Miss
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1300700
Type Of Funding External
Category EXTE
UON Y

Faculty Visiting Fellowship 2013$3,529

Funding body: University of Newcastle - Faculty of Science & IT

Funding body University of Newcastle - Faculty of Science & IT
Project Team Professor Adam McCluskey
Scheme Visiting Fellowship
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1401142
Type Of Funding Internal
Category INTE
UON Y

2014 ARC/NHMRC Fellowship External Applicant Support - FSIT$3,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey, Dr Ali Eshragh
Scheme Special Project Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1301076
Type Of Funding Internal
Category INTE
UON Y

20126 grants / $738,270

Mechanism Of Action Of Dynamin Ring Stabilizer Compounds Controlling The Actin Cytoskeleton $318,510

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Prof Phillip Robinson, Professor Adam McCluskey
Scheme Project Grant
Role Lead
Funding Start 2012
Funding Finish 2014
GNo G1101104
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

The role of clathrin in the spindle assembly checkpoint and as an anticancer target$239,760

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Ms Megan Chircop, Professor Adam McCluskey, Prof Phillip Robinson, Doctor Jennette Sakoff
Scheme Project Grant
Role Lead
Funding Start 2012
Funding Finish 2014
GNo G1101106
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Bioaffinity mass spectrometry infrastructure to identify small molecules binding to therapeutic targets$125,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Ronald Quinn, Associate Professor Sally-Ann Poulsen, Professor Ian Charles, Professor Adam McCluskey, Associate Professor Elizabeth Harry, Professor Johnson Mak
Scheme Equipment Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1100742
Type Of Funding Internal
Category INTE
UON Y

Identification of a novel target for the treatment of hormone positive breast cancer$30,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Jennette Sakoff, Dr JAYNE Gilbert, Professor Adam McCluskey
Scheme Breast Cancer Project Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1200716
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

The role of clathrin in the spindle assembly checkpoint and as an anticancer target$15,000

Funding body: NSW Trade & Investment

Funding body NSW Trade & Investment
Project Team Professor Adam McCluskey, Doctor Jennette Sakoff
Scheme TechVouchers Program
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1200796
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Ultrasonic Homogenizer System and -80 ºC Freezers for chemical and biological sample storage$10,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Adam McCluskey, Professor Eileen McLaughlin, Professor Peter Lewis, Ms Belinda Nixon, Doctor Shaun Roman, Doctor Jennette Sakoff, Associate Professor Ian Grainge
Scheme Equipment Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1100986
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

201113 grants / $3,841,401

Chemical principles underpinning a spermostatic-microbiostatic agent capable of preventing pregnancy and the spread of sexually transmitted disease$775,670

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Laureate Professor John Aitken, Associate Professor Mark Baker, Professor Kenneth Beagley, Professor Adam McCluskey
Scheme Discovery Projects
Role Investigator
Funding Start 2011
Funding Finish 2013
GNo G1000173
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Development of pthaladyn-based dynamin I-selective inhibitors for treatment of epilepsy$544,831

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Adam McCluskey, Prof Phillip Robinson, Professor Terence O'Brien, Ms Megan Chircop, Doctor Jennette Sakoff
Scheme Development Grants
Role Lead
Funding Start 2011
Funding Finish 2013
GNo G1000740
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Establishment of a comprehensive regional biophysical analysis facility $500,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Peter Lewis, Professor Nicholas Dixon, Professor Eileen McLaughlin, Professor Adam McCluskey, Associate Professor Aaron Oakley, Laureate Professor Paul Foster, Laureate Professor John Aitken, Associate Professor Jennifer Beck, Dr Michael Kelso, Professor Graham Nicholson, Associate Professor Elizabeth Harry, Professor Ian Charles, Associate Professor Steven Djordjevic
Scheme Linkage Infrastructure Equipment & Facilities (LIEF)
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1000630
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

Chemical Biology$444,961

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey, Doctor Warwick Belcher, Associate Professor Ian Grainge, Professor Christopher Grof, Professor Peter Lewis, Professor Eileen McLaughlin, Doctor Shaun Roman, Emeritus Professor Ray Rose, Doctor Jennette Sakoff, Doctor Nikki Verrills
Scheme Priority Research Centre
Role Lead
Funding Start 2011
Funding Finish 2015
GNo G1100052
Type Of Funding Internal
Category INTE
UON Y

Sulfonadyn-based dynamin I-specific inhibitors and epilepsy$403,931

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Adam McCluskey, Prof Phillip Robinson
Scheme Project Grant
Role Lead
Funding Start 2011
Funding Finish 2013
GNo G1100148
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Establishment of a Biomolecular Analysis Facility$325,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Peter Lewis, Professor Eileen McLaughlin, Professor Adam McCluskey, Laureate Professor Paul Foster, Laureate Professor John Aitken
Scheme Equipment Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1000465
Type Of Funding Internal
Category INTE
UON Y

Characterisation of a new class of antimicrobial agent for multidrug-resistant infections$257,250

Funding body: Neoculi Pty Ltd

Funding body Neoculi Pty Ltd
Project Team Dr Darren Trott, Professor Adam McCluskey, Mr Stephen Page
Scheme Linkage Projects Partner Funding
Role Lead
Funding Start 2011
Funding Finish 2014
GNo G1100918
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Establishment of a comprehensive regional biophysical analysis facility $230,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Peter Lewis, Professor Nicholas Dixon, Professor Eileen McLaughlin, Professor Adam McCluskey, Associate Professor Aaron Oakley, Laureate Professor Paul Foster, Laureate Professor John Aitken, Associate Professor Jennifer Beck, Dr Michael Kelso, Professor Graham Nicholson, Associate Professor Elizabeth Harry, Professor Ian Charles, Associate Professor Steven Djordjevic
Scheme Linkage Infrastructure Equipment & Facilities (LIEF) Partner Funding
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1100484
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

Characterisation of a new class of antimicrobial agent for multidrug-resistant infections$214,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Dr Darren Trott, Professor Adam McCluskey, Mr Stephen Page
Scheme Linkage Projects
Role Lead
Funding Start 2011
Funding Finish 2014
GNo G1100855
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Dynamin as a new drug target for the treatment of glioblastoma$96,000

Funding body: Cancer Council NSW

Funding body Cancer Council NSW
Project Team Professor Adam McCluskey
Scheme Research Program
Role Lead
Funding Start 2011
Funding Finish 2013
GNo G1100021
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Development of clathrin inhibitors as novel endocytosis inhibitors$25,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Near Miss Grant
Role Lead
Funding Start 2011
Funding Finish 2011
GNo G1001050
Type Of Funding Internal
Category INTE
UON Y

Eppendorf mastercycler pro with thermomixer comfort and 5430R centrifuge$15,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Eileen McLaughlin, Professor Peter Lewis, Professor Adam McCluskey, Conjoint Professor Keith Jones, Professor Brett Nixon, Doctor Shaun Roman, Doctor Jennette Sakoff, Associate Professor Ian Grainge, Doctor Janet Bristow, Doctor Xiao Yang
Scheme Equipment Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1100028
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Restocking the Cupboard - Next generation Antibiotics$9,758

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Linkage Pilot Research Grant
Role Lead
Funding Start 2011
Funding Finish 2011
GNo G1100043
Type Of Funding Internal
Category INTE
UON Y

20109 grants / $3,744,334

Australian Cancer Research Foundation Cancer Research Grant$1,139,509

Funding body: Australian Cancer Research Foundation

Funding body Australian Cancer Research Foundation
Project Team Professor Adam McCluskey
Scheme Cancer Research Grant
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G1000006
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Development of a humane non-surgical sterilization method for domestic animals$1,006,825

Funding body: Found Animals Foundation Inc

Funding body Found Animals Foundation Inc
Project Team Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Adam McCluskey
Scheme Michelson Grants in Reproductive Biology
Role Investigator
Funding Start 2010
Funding Finish 2012
GNo G0900113
Type Of Funding International - Competitive
Category 3IFA
UON Y

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$500,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Adam McCluskey, Laureate Professor John Aitken, Professor Paul Dastoor, Prof Phillip Robinson, Professor Eileen McLaughlin, Emeritus Professor Geoffrey Lawrance, Professor Marcel Maeder, Professor Hugh Dunstan, Doctor Shaun Roman, Conjoint Professor Rob Atkin, Doctor Clovia Holdsworth, Associate Professor Mark Baker, Doctor Nikki Verrills, Professor Gottfried Otting, Professor Brett Nixon, Doctor Xiaojing Zhou, Ms Megan Chircop, Doctor Warwick Belcher
Scheme Linkage Infrastructure Equipment & Facilities (LIEF)
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G0190402
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

Streamlining the dynamin epilepsy drug pipeline$438,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Adam McCluskey, Prof Phillip Robinson, Associate Professor Martin Larsen
Scheme Discovery Projects
Role Lead
Funding Start 2010
Funding Finish 2012
GNo G0190040
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

The 2009 Ramaciotti Major Initiative Biomedical Research Award$300,000

Funding body: Ramaciotti Foundations

Funding body Ramaciotti Foundations
Project Team Professor Adam McCluskey
Scheme Major Initiative for Biomedical Research (Defunct)
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G1000005
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$280,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey, Laureate Professor John Aitken, Professor Paul Dastoor, Prof Phillip Robinson, Professor Eileen McLaughlin, Emeritus Professor Geoffrey Lawrance, Professor Marcel Maeder, Professor Hugh Dunstan, Doctor Shaun Roman, Conjoint Professor Rob Atkin, Doctor Clovia Holdsworth, Associate Professor Mark Baker, Doctor Nikki Verrills, Professor Gottfried Otting, Professor Brett Nixon, Doctor Xiaojing Zhou, Ms Megan Chircop, Doctor Warwick Belcher
Scheme Equipment Grant
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G1000873
Type Of Funding Internal
Category INTE
UON Y

Waters, Ultra high performance liquid chromatography system (nano-Aquity) $30,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Mark Baker, Laureate Professor John Aitken, Professor Adam McCluskey, Professor Brett Nixon, Emeritus Professor John Rostas, Professor Eileen McLaughlin
Scheme Equipment Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G1000051
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

The design of novel, affinity-based technology to specifically isolate phosphotyrosine-containing pedtides$25,000

Funding body: Hunter Children`s Research Foundation

Funding body Hunter Children`s Research Foundation
Project Team Associate Professor Mark Baker, Professor Adam McCluskey
Scheme Research Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G0900191
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Centre for Kinomics$25,000

Funding body: John Morris Scientific Pty Ltd

Funding body John Morris Scientific Pty Ltd
Project Team Professor Adam McCluskey
Scheme Research Grant
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G1000614
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20096 grants / $1,086,416

Development of dynamin inhibitors as novel therapies for epilepsy$306,001

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Adam McCluskey
Scheme Project Grant
Role Lead
Funding Start 2009
Funding Finish 2011
GNo G0190116
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Preclinical new chemical entities as novel anti-epileptic drugs targeting dynamin$94,758

Funding body: Epilepsy Foundation of America

Funding body Epilepsy Foundation of America
Project Team Professor Adam McCluskey
Scheme New Therapy Grants Program
Role Lead
Funding Start 2009
Funding Finish 2010
GNo G1000613
Type Of Funding International - Competitive
Category 3IFA
UON Y

Dynamin as a new drug target for he treatment of glioblastoma$74,457

Funding body: James S. McDonnell Foundation

Funding body James S. McDonnell Foundation
Project Team Professor Adam McCluskey, Ms Megan Chircop
Scheme Research Award
Role Lead
Funding Start 2009
Funding Finish 2009
GNo G0190466
Type Of Funding International - Non Competitive
Category 3IFB
UON Y

Development of novel anti-epileptic drugs targeting vesicular endocytosis$66,200

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Adam McCluskey
Scheme Development Grants
Role Lead
Funding Start 2009
Funding Finish 2009
GNo G0190117
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

20085 grants / $3,041,290

HMRI Cancer Research Program - MRSP Infrastructure$1,031,290

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Conjoint Professor Stephen Ackland, Emeritus Professor Leonie Ashman, Professor John Forbes, Conjoint Professor Jim Denham, Conjoint Professor Peter Hersey, Professor Gordon Burns, Professor Adam McCluskey, Doctor Nikki Verrills
Scheme NSW MRSP Infrastructure Grant
Role Investigator
Funding Start 2008
Funding Finish 2009
GNo G0188622
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Integrated surface fabrication and characterisation laboratory$750,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Paul Dastoor, Professor John O'Connor, Professor Bruce King, Professor Adam McCluskey, Doctor Warwick Belcher, Professor Catherine Stampfl, Dr Jeffrey Reimers, Assoc. Prof Alexander Hamilton, Dr Adam Micolich, Doctor Chris Fell, Dr Scott Watkins, Dr Mark Bown, Dr Anton Stampfl, Dr Peter Evans
Scheme Linkage Infrastructure Equipment & Facilities (LIEF)
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo G0187931
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

The discovery and validation of novel drug classes against parasites of major economic importance$670,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Adam McCluskey, Professor Robin Gasser, Dr Jennette Sakoff
Scheme Linkage Projects
Role Lead
Funding Start 2008
Funding Finish 2010
GNo G0187815
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Partner contributions for Integrated surface fabrication and characterisation laboratory$320,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Paul Dastoor, Professor John O'Connor, Professor Bruce King, Professor Adam McCluskey, Doctor Warwick Belcher, Professor Catherine Stampfl, Dr Jeffrey Reimers, Assoc. Prof Alexander Hamilton, Dr Adam Micolich, Doctor Chris Fell, Dr Scott Watkins, Dr Mark Bown, Dr Anton Stampfl, Dr Peter Evans
Scheme Linkage Infrastructure Equipment & Facilities (LIEF) Partner Funding
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo G0189562
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

The discovery and validation of novel drug classes against parasites of major economic importance$270,000

Funding body: Genetic Technologies Limited

Funding body Genetic Technologies Limited
Project Team Professor Adam McCluskey, Professor Robin Gasser, Dr Jennette Sakoff
Scheme Linkage Projects Partner Funding
Role Lead
Funding Start 2008
Funding Finish 2010
GNo G0188378
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20074 grants / $693,942

Chemical listening devices: Novel sensors targeting the clandestine manufacture and transport of illicit drugs and explosives$378,942

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer, Doctor Clovia Holdsworth, Professor Christopher Lennard
Scheme Linkage Projects
Role Lead
Funding Start 2007
Funding Finish 2009
GNo G0186611
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Chemical listening devices: Novel sensors targeting the clandestine manufacture and transport of illicit drugs and explosives$105,000

Funding body: Australian Federal Police

Funding body Australian Federal Police
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer, Doctor Clovia Holdsworth, Professor Christopher Lennard
Scheme Linkage Projects Partner Funding
Role Lead
Funding Start 2007
Funding Finish 2009
GNo G0187330
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Selective Detection and Removal of Organochlorine Residues via MIPs$105,000

Funding body: Entech Industries Pty Ltd

Funding body Entech Industries Pty Ltd
Project Team Professor Adam McCluskey, Doctor Clovia Holdsworth, Associate Professor Michael Bowyer
Scheme Postgraduate Research Scholarship
Role Lead
Funding Start 2007
Funding Finish 2010
GNo G0187721
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Selective Detection and Removal of Organochlorine Residues via MIPs$105,000

Funding body: Entech Industries Pty Ltd

Funding body Entech Industries Pty Ltd
Project Team

A/Prof Adam McCluskey

Scheme Industry
Role Lead
Funding Start 2007
Funding Finish 2007
GNo
Type Of Funding External
Category EXTE
UON N

20063 grants / $239,900

Consequences of Dynamin 2 PH Domain Dysfunction in Charcot-Marie-Tooth Neuropathy$217,500

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Adam McCluskey
Scheme Project Grant
Role Lead
Funding Start 2006
Funding Finish 2008
GNo G0186208
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Chemical Interventions in Neurological Diseases?$20,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Near Miss Grant
Role Lead
Funding Start 2006
Funding Finish 2006
GNo G0186050
Type Of Funding Internal
Category INTE
UON Y

BIT's 4th Annual Congress of International Drug Discovery Science & Technology 25 May - 2 June 2006$2,400

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Travel Grant
Role Lead
Funding Start 2006
Funding Finish 2006
GNo G0186202
Type Of Funding Internal
Category INTE
UON Y

20051 grants / $207,189

20048 grants / $695,039

Selective detection and removal of contaminants that have an adverse impact on Australian raw sugar quality$190,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer, Dr M O'Shea
Scheme Linkage Projects
Role Lead
Funding Start 2004
Funding Finish 2006
GNo G0183626
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Biacore3000-Expansion of Proteomics Facility$187,341

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Alistair Sim, Laureate Professor John Aitken, Emeritus Professor Peter Dunkley, Emeritus Professor John Rostas, Associate Professor Phillip Dickson, Emeritus Professor Leonie Ashman, Laureate Professor Roger Smith, Professor Gordon Burns, Professor Adam McCluskey, Associate Professor Paul Tooney, Dr Fraser Ross, Emeritus Professor Ray Rose
Scheme Linkage Infrastructure Equipment & Facilities (LIEF)
Role Investigator
Funding Start 2004
Funding Finish 2004
GNo G0183030
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

In-field sensors for the detection of illicit drugs$171,336

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer
Scheme Linkage Projects
Role Lead
Funding Start 2004
Funding Finish 2006
GNo G0184254
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Selective detection and removal of contaminants that have adverse impact on Australian raw sugar quality$51,000

Funding body: Bureau of Sugar Experiment Stations

Funding body Bureau of Sugar Experiment Stations
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer
Scheme Linkage Projects Partner Funding
Role Lead
Funding Start 2004
Funding Finish 2006
GNo G0184030
Type Of Funding Not Known
Category UNKN
UON Y

In-field sensors for the detection of illicit drugs$45,000

Funding body: Australian Federal Police

Funding body Australian Federal Police
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer
Scheme Linkage Projects Partner Funding
Role Lead
Funding Start 2004
Funding Finish 2006
GNo G0185067
Type Of Funding Not Known
Category UNKN
UON Y

Improving Drug Development: New Approaches to Rapid Development of Novel Lead Compounds$27,542

Funding body: Ramaciotti Foundations

Funding body Ramaciotti Foundations
Project Team Professor Adam McCluskey
Scheme Major Equipment Award
Role Lead
Funding Start 2004
Funding Finish 2004
GNo G0183187
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

New drugs targeting protein kinases$17,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Emeritus Professor Leonie Ashman, Professor Adam McCluskey
Scheme Research Grant
Role Investigator
Funding Start 2004
Funding Finish 2004
GNo G0183751
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Radiocarbon dating of heroin samples as a tool to verify the conversion to alternative crops.$5,820

Funding body: AINSE (Australian Institute of Nuclear Science & Engineering)

Funding body AINSE (Australian Institute of Nuclear Science & Engineering)
Project Team Professor Adam McCluskey
Scheme Use of Facilities Only
Role Lead
Funding Start 2004
Funding Finish 2004
GNo G0183703
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

20034 grants / $475,309

Implementation of a Methamphetamine Method for the Australian Federal Police$230,309

Funding body: Australian Federal Police

Funding body Australian Federal Police
Project Team Professor Adam McCluskey
Scheme Research Grant
Role Lead
Funding Start 2003
Funding Finish 2005
GNo G0184304
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Dynamin inhibitors as tools for dissecting the endocytic pathways neurons$165,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Adam McCluskey
Scheme Project Grant
Role Lead
Funding Start 2003
Funding Finish 2005
GNo G0182859
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

High Pressure and Fluorous Approaches to fostriecin libraries: New Therapeutic Opportunities.$50,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Adam McCluskey, Assoc. Prof David Young, Doctor Jennette Sakoff
Scheme Discovery Projects
Role Lead
Funding Start 2003
Funding Finish 2003
GNo G0182117
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Implementation of a Methamphetamine Method for the Australian Federal Police$30,000

Funding body: Australian Federal Police

Funding body Australian Federal Police
Project Team Professor Adam McCluskey
Scheme Equipment Grant
Role Lead
Funding Start 2003
Funding Finish 2003
GNo G0184303
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20024 grants / $598,000

Antagonist of Corticotrophin Releasing Hormone as Therapeutic Agents for the Prevention of Premature Birth in Humans$375,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Adam McCluskey, Dr P Keller, Laureate Professor Roger Smith, Dr A Ruhmann
Scheme Project Grant
Role Lead
Funding Start 2002
Funding Finish 2004
GNo G0180905
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Devevelopement and Use of Ionic Liquids in Metal Recovery from Ores, Concentrates and Mattes.$205,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Emeritus Professor Geoffrey Lawrance, Dr I Hamilton, Professor Adam McCluskey
Scheme Discovery Projects
Role Investigator
Funding Start 2002
Funding Finish 2004
GNo G0181087
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

New targets for chemotherapy: anti-cancer drugs that target protein phosphatases$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey, Conjoint Professor Stephen Ackland, Doctor Jennette Sakoff
Scheme Project Grant
Role Lead
Funding Start 2002
Funding Finish 2002
GNo G0181459
Type Of Funding Internal
Category INTE
UON Y

Development of new therapeutic agents for the treatment of epilepsy$8,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Project Grant
Role Lead
Funding Start 2002
Funding Finish 2002
GNo G0181460
Type Of Funding Internal
Category INTE
UON Y

20014 grants / $47,668

Selective detection of Trichloroanisole and other flavour contaminants in wines using molecularly imprinted polymer technology.$30,268

Funding body: Wine Australia

Funding body Wine Australia
Project Team Professor Adam McCluskey
Scheme Project Grant
Role Lead
Funding Start 2001
Funding Finish 2002
GNo G0181473
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Development of new drugs for the prevention of premature birth$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Project Grant
Role Lead
Funding Start 2001
Funding Finish 2001
GNo G0180062
Type Of Funding Internal
Category INTE
UON Y

Environmentally friendly ('Green') organic chemistry: Development of novel methodologies and reagents.$5,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Project Grant
Role Lead
Funding Start 2001
Funding Finish 2001
GNo G0180014
Type Of Funding Internal
Category INTE
UON Y

92nd American Association for Cancer Research Annual Meeting, USA 24-28 March 2001$2,400

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Travel Grant
Role Lead
Funding Start 2001
Funding Finish 2001
GNo G0180691
Type Of Funding Internal
Category INTE
UON Y

20003 grants / $43,950

Selective detection of Trichloroanisole and other flavour contaminants in wines using molecularly imprinted polymer technology.$26,950

Funding body: Wine Australia

Funding body Wine Australia
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer
Scheme Project Grant
Role Lead
Funding Start 2000
Funding Finish 2000
GNo G0180158
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Synthesis of Drugs for Prevention of Pre-Term Delivery.$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey, Laureate Professor Roger Smith
Scheme Project Grant
Role Lead
Funding Start 2000
Funding Finish 2000
GNo G0178828
Type Of Funding Internal
Category INTE
UON Y

Towards Green Chemistry: The Development of Environmentally Organic Synthesis.$7,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Project Grant
Role Lead
Funding Start 2000
Funding Finish 2000
GNo G0178827
Type Of Funding Internal
Category INTE
UON Y

19995 grants / $78,500

Selective Inhibitors of Protein Phosphatases as Anti-cancer agents$25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Jennette Sakoff, Professor Adam McCluskey, Conjoint Professor Stephen Ackland
Scheme Research Grant
Role Investigator
Funding Start 1999
Funding Finish 1999
GNo G0178390
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Selective detection of Trichloroanisole and other flavour contaminants in wines using molecularly imprinted polymer technology$20,000

Funding body: Wine Australia

Funding body Wine Australia
Project Team Professor Adam McCluskey, Associate Professor Michael Bowyer
Scheme Project Grant
Role Lead
Funding Start 1999
Funding Finish 1999
GNo G0178612
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Rapid Microscale Synthesis of Drugs for the Prevention of Pre-Term Delivery$13,500

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey, Laureate Professor Roger Smith
Scheme Project Grant
Role Lead
Funding Start 1999
Funding Finish 1999
GNo G0178022
Type Of Funding Internal
Category INTE
UON Y

Development of a Versatile, Sensitive, Non-Isotopoic Method for Detecting Phosphorylated and Glycosylated Serines in Proteins and Peptides$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Emeritus Professor John Rostas, Professor Adam McCluskey
Scheme Collaborative Research Grant
Role Investigator
Funding Start 1999
Funding Finish 1999
GNo G0178350
Type Of Funding Internal
Category INTE
UON Y

RMC Collab Partner.Development of a Versatile, Sensitive, Non-Isotopic Method for Detecting Phosphorylated and Glucosylated Serines in Proteins & Peptides.$10,000

Funding body: Bio-Rad Laboratories Pty Ltd (Australia)

Funding body Bio-Rad Laboratories Pty Ltd (Australia)
Project Team Emeritus Professor John Rostas, Professor Adam McCluskey
Scheme Research Grant
Role Investigator
Funding Start 1999
Funding Finish 1999
GNo G0178764
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

19983 grants / $59,164

Low molecular weight ligands for corticotrophin releasing hormone receptors: Drugs for intervention during human pregnancy$47,664

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey, Dr P Keller, Laureate Professor Roger Smith
Scheme Special Scholarship Initiative Grants
Role Lead
Funding Start 1998
Funding Finish 2000
GNo G0177742
Type Of Funding Internal
Category INTE
UON Y

Computer Modelling and Graphical Representation of the Three Dimensional Structure of Protein Phosphatases$9,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Project Grant
Role Lead
Funding Start 1998
Funding Finish 1998
GNo G0177303
Type Of Funding Internal
Category INTE
UON Y

XVth EFMC International Symposium on Medicinal Chemistry, Scotland 6-10 September 1998$2,500

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Travel Grant
Role Lead
Funding Start 1998
Funding Finish 1998
GNo G0180347
Type Of Funding Internal
Category INTE
UON Y

19973 grants / $38,000

Computer Asisted Design and Chemical Synthesis of Novel Therapeutic Agents Affecting Pregnancy the Duration of Human Pregnancy$16,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Laureate Professor Roger Smith, Professor Adam McCluskey, Professor Alan Boura
Scheme Small Grant
Role Investigator
Funding Start 1997
Funding Finish 1997
GNo G0176726
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

Design and Synthesis of Novel Corticotropin-Releasing Hormone Receptors Agaonists/Antagonists: Development of New Therapeutic Agents$15,000

Funding body: Ramaciotti Foundations

Funding body Ramaciotti Foundations
Project Team Professor Adam McCluskey, Ian Leitch
Scheme Research Grant
Role Lead
Funding Start 1997
Funding Finish 1997
GNo G0176500
Type Of Funding Aust Competitive - Non Commonwealth
Category 1NS
UON Y

Development Of A Novel, Photolytic Oxidising Agent For Use In Synthetic Chemistry.$7,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme Project Grant
Role Lead
Funding Start 1997
Funding Finish 1997
GNo G0176634
Type Of Funding Internal
Category INTE
UON Y

19961 grants / $12,500

Design & Synthesis ofNovel Protein Phosphatase 1 & Protein Phosphatase 2A Inhibitors$12,500

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey
Scheme New Staff Grant
Role Lead
Funding Start 1996
Funding Finish 1996
GNo G0176326
Type Of Funding Internal
Category INTE
UON Y
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Research Supervision

Number of supervisions

Completed27
Current8

Total current UON EFTSL

PhD3.25

Current Supervision

Commenced Level of Study Research Title Program Supervisor Type
2017 PhD Extraction and Use of Citrus Oil as Fungicide on Citrus Fruits PhD (Food Science), Faculty of Science, The University of Newcastle Principal Supervisor
2017 PhD Synthesis, Biological Activities of a,ß-unsaturated Carbonyl Compounds PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2016 PhD Development of Morphlocks to Further Understanding of Dynamin's Allosteric Regulation PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2016 PhD Targeting the S100A2 Axis as a Novel Therapeutic Target for Pancreatic Cancer PhD (Biological Sciences), Faculty of Science, The University of Newcastle Co-Supervisor
2014 PhD Novel Classes of Iminosugars as Glycosidase Inhibitors via a Flow Chemistry Approach PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2013 PhD Inhibiting the NusB-NusE Protein-Protein Interaction - A Novel Target for Antibiotic Drug Development PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2010 PhD Application of Green Chemistry Approaches to Cytotoxic Compounds PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2010 PhD The Characterisation and Classification of Residual Tool Marks on Bone Inflicted by Machetes and Samurai Swords (Sharp and Blunt) and the Survivability of Those Marks Following Thermal Trauma (Fire). PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor

Past Supervision

Year Level of Study Research Title Program Supervisor Type
2017 PhD The Consequences of Paternal Acrylamide Exposure and Potential for Amelioration PhD (Biological Sciences), Faculty of Science, The University of Newcastle Co-Supervisor
2017 PhD Synthesis of Bolinaquinone Analogues as Clathrin Inhibitors and Cytotoxic Agents PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2017 PhD Small Molecule Inhibitors of the Hedgehog Signalling Pathways as Cancer Suppressing Agents PhD (Biological Sciences), Faculty of Science, The University of Newcastle Principal Supervisor
2015 PhD The Development of Flow Chemistry Methodologies for the Synthesis of Potential Anti-Cancer Agents PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2014 PhD Exploring Signal Transduction Mechanisms in Molecularly Imprinted Polymers for Forensic Applications PhD (Chemistry), Faculty of Science, The University of Newcastle Co-Supervisor
2014 PhD Drugs from Nature: 1. Dynamin I Inhibitors from Mexican Marine Algae; 2. Chemical Investigation of an Australian Aboriginal Traditional Remedy PhD (Chemistry), Faculty of Science, The University of Newcastle Co-Supervisor
2013 PhD Design and Synthesis of Molecularly Imprinted Polymers for the Selective Extraction of Polychlorinated Biphenyls PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2013 PhD Synthesis and Evaluation of Norcantharidin and Acrylonitrile Derivatives as Potential Anti-Cancer Agents PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2013 PhD A Mechanistic Study into the Reaction Between Carbon Dioxide and Amines PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2012 PhD 1. Dynamin-l Inhibitors from Sessile Marine Invertebrates; 2. Chemotaxonomy of Cystophora spp. PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2012 PhD Disruption of Clathrin Mediated-Endocytosis through Small Molecule Inhibition of Dynamin and Clathrin PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2012 PhD Synthesis, Characterisation and Evaluation of Biphenyl Monomers for Molecular Imprinting Applications PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2011 Masters Novel Inhibitors of Clathrin Mediated Endocytosis M Philosophy (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2010 PhD Towards the Development of a Benzylpiperazine Specific Molecular Imprinted Polymer PhD (Chemistry), Faculty of Science, The University of Newcastle Co-Supervisor
2010 PhD Optimisation of Molecularly Imprinted Polymeric Films for the Detection of L-Ephedrine PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2010 PhD Characterisation and Improved Performance of Molecularly Imprinted Polymers Prepared Using Room Temperature Ionic Liquids PhD (Chemistry), Faculty of Science, The University of Newcastle Co-Supervisor
2009 PhD Norcantharidin Analogues: PP1 and PP2A Inhibition and Potential Therapeutic Development PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2008 PhD Ionic Liquids for Synthesis and Metal Recovery PhD (Chemistry), Faculty of Science, The University of Newcastle Co-Supervisor
2008 PhD Design and Synthesis of Molecularly Imprinted Polymers for the Selective Recognition of Small Chloro-Arene Contaminants PhD (Chemistry), Faculty of Science, The University of Newcastle Principal Supervisor
2007 PhD Design and Synthesis of Novel Dynamin GTPase Inhibitors PhD (Chemistry), Faculty of Science, The University of Newcastle Sole Supervisor
2006 PhD Cantharidin Analogues: Potential Therapeutic Agents PhD (Chemistry), Faculty of Science, The University of Newcastle Sole Supervisor
2006 PhD Ionic Liquids for Explosive Technologies PhD (Chemistry), Faculty of Science, The University of Newcastle Co-Supervisor
2006 PhD Novel Inhibitors of Dynamin GTPase PhD (Chemistry), Faculty of Science, The University of Newcastle Sole Supervisor
2006 PhD New Routes To Precious Metal Recovery Using Ionic Liquids PhD (Chemistry), Faculty of Science, The University of Newcastle Co-Supervisor
2005 PhD Chemotaxonomy of the brown algal genus Cyclophoria PhD (Chemistry), Faculty of Science, The University of Newcastle Co-Supervisor
2004 PhD Design and Synthesis of Potential CRHR1 Antagonists PhD (Chemistry), Faculty of Science, The University of Newcastle Sole Supervisor
2004 PhD Development Towards Structurally Unprecedented Corticotropin Releasing Hormone Type-1 Receptor Antagonists PhD (Chemistry), Faculty of Science, The University of Newcastle Sole Supervisor
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Research Collaborations

The map is a representation of a researchers co-authorship with collaborators across the globe. The map displays the number of publications against a country, where there is at least one co-author based in that country. Data is sourced from the University of Newcastle research publication management system (NURO) and may not fully represent the authors complete body of work.

Country Count of Publications
Australia 189
United Kingdom 20
United States 20
Germany 14
Sweden 6
More...
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News

NHMRC

NHMRC funding success 2016

November 10, 2015

Professor Adam McCluskey has been awarded more than $1,193,000 in NHMRC Project Grant funding commencing in 2016 for his research project A new approach to treating intractable epilepsy.

ERA Research Evaluation Committees 2015

ERA Research Evaluation Committees 2015

February 20, 2015

Nine University of Newcastle researchers have been selected by the Australian Research Council for membership of the 2015 Excellence in Research for Australia (ERA) Research Evaluation Committees.

Smoking and male fertility breakthrough finding

October 1, 2014

Mothers who smoke while they are pregnant or breast feeding may be damaging the future fertility of their sons, according to breakthrough findings from University of Newcastle researchers published today.

Professor Adam McCluskey

Position

Professor
School of Environmental and Life Sciences
Faculty of Science

Focus area

Chemistry

Contact Details

Email adam.mccluskey@newcastle.edu.au
Phone 0249216486
Fax 0249215472

Office

Room SC318
Building Science.
Location Callaghan
University Drive
Callaghan, NSW 2308
Australia
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