Available in 2021
Course code



10 units


4000 level

Course handbook


Presents the pathophysiology of altered health states and their management including both pharmacological and non-pharmacological interventions. Specific conditions covered in this course include oncology, haematology, palliation, emergency medicine and transplant medicine. The course considers aspects of pharmacy practice including a systematic review of prescription and non-prescription medications and Complementary and Alternate Medicines, which will address the quality use of medicines in the management of these conditions. Advanced drug information will be included in this course.

The course builds on student's existing knowledge and understanding of the physical pharmacy principles and provides students with an understanding of how these principles are applied to the preparation of cytotoxic drug products. The course builds also on the student's existing knowledge and understanding of the basic pharmacokinetic principles and provides students with an understanding of its application to advanced clinical pharmacokinetics. Population pharmacokinetics and toxicokinetics will be expanded on in this course.

Application of the knowledge developed in this course will be complemented by clinical skills training.

Availability2021 Course Timetables


  • Semester 1 - 2021

Learning outcomes

On successful completion of the course students will be able to:

1. Explain the pathophysiology and the management of conditions requiring critical care, including severe burns.

2. Explain the pathophysiology and management of conditions including neoplastic disorders, palliative care.

3. Describe the immunological basis of transplant medicine and the agents used in the management of transplant patients.

4. Explain the signs, symptoms and complications of opportunistic infections and systemic fungal disease; the pathogens involved, relevant diagnostic tests and be aware of first and second line infective therapy as well as non-pharmacological approaches to the management of these infections.

5. Use advanced drug information skills to describe the quality use of medicines' issues surrounding these therapeutic agents in the treatment of these conditions and continue to develop clinical skills and communication skills in the therapeutic management of these conditions.

6. Develop skills in the appropriate use of non-prescription products and advice on non-pharmacological treatment options in the management of these conditions.

7. Describe the techniques and processes involved in the preparation of cytotoxic drug products.

8. Apply advanced principles of pharmacodynamics and pharmacokinetics to clinical practice including population pharmacokinetics and toxicokinetics.


1. This course will cover the pathophysiology, therapeutic treatment and pharmacy practice issues in the management of:

-  Emergency/ critical care patients (including severe burns, critical care therapy, fluid and electrolyte therapy and acid-base balance).

-  Neoplastic disorders (including leukemias, lymphomas, breast cancer, lung cancer, gastrointestinal cancers, gynaecological cancers, prostrate cancer, skin cancers and melanomas and liver cancers).

-  Palliative care.

-  Clients undergoing transplants, including renal, heart-lung, bone-marrow and skin grafts.

2. The pathophysiology and principles for the treatment of opportunistic infections and systemic fungal disease.

3. The concept of minor illness and major disease will be discussed, including the use of prescription and non-prescription products, including Complementary and Alternate Medicines. Non-pharmacological approaches to the management of these conditions and will also be discussed.

4. The course covers all pharmacokinetic considerations for therapeutic agents used in emergency medicine, oncology, toxicology and palliation. The application of clinical pharmacokinetics is covered thoroughly in this course.

5. Advanced drug information skills will be taught and applied in this course.

6. The preparation of cytotoxic drug products.


To enrol in this course students must have successfully completed all 3000 level courses within the Bachelor of Pharmacy (Honours) [12328] program and be active in this program.

Assumed knowledge

PHAR3203 Clinical Pharmacotherapy 3

Assessment items

Formal Examination: Written Formal exam *

In Term Test: Mid -semester written exam

Quiz: Online quizzes

* This assessment has a compulsory requirement.

Compulsory Requirements

In order to pass this course, each student must complete ALL of the following compulsory requirements:

Course Assessment Requirements:

  • Formal Examination: Pass Requirement - Students must pass this assessment item to pass the course.

Contact hours



Online 3 hour(s) per Week for 8 Weeks


Face to Face On Campus 16 hour(s) per Term Full Term

Includes in term exam


Face to Face On Campus 2 hour(s) per Week for 8 Weeks

The University of Newcastle acknowledges the traditional custodians of the lands within our footprint areas: Awabakal, Darkinjung, Biripai, Worimi, Wonnarua, and Eora Nations. We also pay respect to the wisdom of our Elders past and present.