PHAR2202
10 units
2000 level
Course handbook
Description
The first part of the course follows the evolution of drugs through time covering the principles of drug discovery in the areas of pharmacognosy and natural products; synthetic medicinal chemistry and the development of medicinal substances. The course will focus on their chemistry and in particular how the chemical structure of a drug relates to its biological activity. The drug development pipeline from lead discovery to clinical trials will be introduced and concepts around regulatory affairs, patenting, registration and marketing will be covered in the context of new drug discovery. The second part of the course will focus on analytical methods relevant to drug testing and quality control. Students are introduced to the fundamental instrumental methods of chemical analysis commonly used in pharmaceutical laboratories and basic separation and purification techniques including chromatography and electrophoresis.
Availability2024 Course Timetables
Callaghan
- Semester 1 - 2024
Learning outcomes
On successful completion of the course students will be able to:
1. Describe and compare common sources of drugs and contemporary approaches to drug discovery and design
2. Identify drug targets as a recognition site for pharmaceutical agents and explain how the chemical structure of a substance influences interaction with a drug target
3. Understand the process of preclinical and clinical drug development including safety, stability, formulation and regulatory affairs
4. Describe, compare and apply analytical methods for the separation, identification and quantitation of pharmaceutical and other biologically active compounds
5. Work safely and competently in a chemical laboratory
6. Contribute to team and group work for scientific investigation and reporting
Content
1. Introduction to Drug Design and Development
2. Drug targets
3. Lead discovery and modification
4. Pre-clinical testing
5. Biopharmaceuticals
6. Drug delivery
7. Clinical trials and regulatory affairs
8. Molecular Spectrophotometry
9. Atomic Spectroscopy
10. Chromatography
11. Electrophoresis
12. Data treatment
Requisite
This course is only available to students enrolled in the Bachelor of Pharmacy (Honours) [12328] or Bachelor of Biomedical Science [40097] programs, and have successfully completed CHEM1010.
Assumed knowledge
CHEM1010 Introductory Chemistry I, CHEM1020 Introductory Chemistry II , PHAR1201 Introduction to Formulation Sciences
Assessment items
In Term Test: In Term Test 1
Compulsory Requirement: Pass requirement - Must pass this assessment item to pass the course.
In Term Test: In Term Test 2
Compulsory Requirement: Pass requirement - Must pass this assessment item to pass the course.
Tutorial / Laboratory Exercises: Workshop/ Laboratory Participation and Assignment Report
Contact hours
Semester 1 - 2024 - Callaghan
Lectorial-1
- Face to Face On Campus 1 hour(s) per week(s) for 6 week(s)
Lectorial-2
- Face to Face On Campus 2 hour(s) per week(s) for 6 week(s)
Lecture-1
- Face to Face On Campus 2 hour(s) per week(s) for 2 week(s)
- Exams
Lecture-2
- Face to Face On Campus 1 hour(s) per week(s) for 6 week(s)
Lecture-3
- Face to Face On Campus 2 hour(s) per week(s) for 6 week(s) starting in week 1
Practical-1
- Face to Face On Campus 3 hour(s) per week(s) for 5 week(s)
- Compulsory Requirement: Students must attend 80% of sessions.
Workshop-1
- Face to Face On Campus 2 hour(s) per week(s) for 5 week(s)
- Compulsory Requirement: Students must attend 80% of sessions.
Course outline
Course outline not yet available.
The University of Newcastle acknowledges the traditional custodians of the lands within our footprint areas: Awabakal, Darkinjung, Biripai, Worimi, Wonnarua, and Eora Nations. We also pay respect to the wisdom of our Elders past and present.