This course will build on the knowledge gained in the Year 1 Human Bioscience course: HUBS1404 Biomedical Science Part 2. Students will learn general principles of infection and immunity including the growth and metabolism of human microbial pathogens, mechanisms of microbial pathogenesis and infection control strategies. Students will also learn about host defence mechanisms to combat microbial infections.
Availability2021 Course Timetables
- Semester 1 - 2021
On successful completion of the course students will be able to:
1. Describe the basic structures and growth characteristics of bacteria and viruses.
2. Demonstrate knowledge of contemporary biomedical and molecular techniques to diagnose and characterize infectious microbes.
3. Describe prevention and treatment strategies for infectious diseases.
4. Describe human immunity and the development of immune responses that are important in the prevention and development of disease.
5. Demonstrate how to research topics, seek out information and solve problems in microbiology and immunology.
6. Demonstrate practical skills necessary to conduct laboratory-based investigations in microbiology and immunology.
7. Analyse, discuss and present laboratory-based data and scientific information in written and oral forms of communication.
- Microbial diversity and structure
- Bacterial nutrition, metabolism, growth and study
- Bacterial genetics and evolution
- Bacterial virulence factors and their regulation,
- Pathogenicity islands secretion systems
- Microbial pathogenicity and epidemiology
- Mechanisms of bacterial pathogenicity
- Understand virus structure and what makes them different to eukaryotes/prokaryotes. Brief understanding of methods of diagnosis
- Broad understanding of the classification of different viruses that are important to human disease
- Broad understanding of different replication strategies employed by different viruses
- Understand how viruses alter cells to cause disease (i.e. Affect on host cells, changes in host immunity, tissue tropism, pathogenesis etc)
- Understand how vaccines work, how they are designed and the advantages/dis-advantages of the different types of vaccines (e.g. attenuated Vs killed)
- Understand the different targets of antiviral drugs. As well as understand how and why are these antivirals are designed to be specific to viruses
- Comprehensive review of a number of important gastrointestinal viruses and respiratory viruses
- For completeness there will also be a lecture on Eukaryotic Microorganisms
- Immune System: Structure & Components
- Innate Immunity (1): First Line of Defence
- Innate Immunity (2): Induced Response
- Adaptive Immunity (1): Antigen Presentation
- Adaptive Immunity (2): T-cell/ B-cell activation & function
- Cytokines/Chemookines & Their Receptors: Role in coordinating the immune response
- The Immune System & Disease: Asthma & Allergy
This course is only available to students enrolled in the Bachelor of Biomedical Science or Bachelor of Pharmacy (Honours) programs.
HUBS1403 Biomedical Science Part 1 and HUBS1404 Human Bioscience Part 2 or equivalent
In Term Test: Mid semester tests *
Formal Examination: Final exam *
Tutorial / Laboratory Exercises: Laboratory reports *
Tutorial / Laboratory Exercises: Laboratory Skills
* This assessment has a compulsory requirement.
In order to pass this course, each student must complete ALL of the following compulsory requirements:
General Course Requirements:
- Laboratory: There is a compulsory attendance requirement in this course. - This course has learning outcomes and assessment that relate to laboratory skills, so it is a requirement that you achieve a satisfactory level of attendance at laboratory sessions. Students who miss a laboratory session, and have grounds for special circumstances, will be provided alternative arrangements to meet these objectives & complete the assessment
Course Assessment Requirements:
- Tutorial / Laboratory Exercises: Pass Requirement - Students must pass this assessment item to pass the course. - Students must pass the final examination and continual assessment (combination of 2 x in class exams, 2 x lab reports/essays) to be able to pass the course overall.
- Formal Examination: Pass Requirement - Students must pass this assessment item to pass the course. - Students must pass the final examination and continual assessment (combination of 2 x in class exams, 2 x lab reports/essays) to be able to pass the course overall.
- In Term Test: Pass Requirement - Students must pass this assessment item to pass the course. - Students must pass the final examination and continual assessment (combination of 2 x in class exams, 2 x lab reports/essays) to be able to pass the course overall.
Face to Face On Campus 3 hour(s) per Week for 4 Weeks
Face to Face On Campus 28 hour(s) per Term Full Term
Includes in-term examinations
Face to Face On Campus 1 hour(s) per Week for 11 Weeks
The University of Newcastle acknowledges the traditional custodians of the lands within our footprint areas: Awabakal, Darkinjung, Biripai, Worimi, Wonnarua, and Eora Nations. We also pay respect to the wisdom of our Elders past and present.