Available in 2018
Course code

HUBS2601

Units

10 units

Level

2000 level

Course handbook

Description

This course will build on the knowledge gained in the Year 1 Human Bioscience course: HUBS1404 Biomedical Science Part 2. Students will learn general principles of infection and immunity including the growth and metabolism of human microbial pathogens, mechanisms of microbial pathogenesis and infection control strategies. Students will also learn about host defence mechanisms to combat microbial infections.


Availability

Callaghan

  • Semester 1 - 2018

Learning outcomes

On successful completion of the course students will be able to:

1. Describe the basic structures and growth characteristics of bacteria and viruses.

2. Demonstrate knowledge of contemporary biomedical and molecular techniques to diagnose and characterize infectious microbes.

3. Describe prevention and treatment strategies for infectious diseases.

4. Describe human immunity and the development of immune responses that are important in the prevention and development of disease.

5. Demonstrate how to research topics, seek out information and solve problems in microbiology and immunology.

6. Demonstrate practical skills necessary to conduct laboratory-based investigations in microbiology and immunology.

7. Analyse, discuss and present laboratory-based data and scientific information in written and oral forms of communication.


Content

Bacteriology

  1. Microbial diversity and structure
  2. Bacterial nutrition, metabolism, growth and study
  3. Bacterial genetics and evolution
  4. Bacterial virulence factors and their regulation,
  5. Pathogenicity islands secretion systems
  6. Microbial pathogenicity and epidemiology
  7. Mechanisms of bacterial pathogenicity

Virology

  1. Understand virus structure and what makes them different to eukaryotes/prokaryotes. Brief understanding of methods of diagnosis
  2. Broad understanding of the classification of different viruses that are important to human disease
  3. Broad understanding of different replication strategies employed by different viruses
  4. Understand how viruses alter cells to cause disease (i.e. Affect on host cells, changes in host immunity, tissue tropism, pathogenesis etc)
  5. Understand how vaccines work, how they are designed and the advantages/dis-advantages of the different types of vaccines (e.g. attenuated Vs killed)
  6. Understand the different targets of antiviral drugs. As well as understand how and why are these antivirals are designed to be specific to viruses
  7. Comprehensive review of a number of important gastrointestinal viruses and respiratory viruses
  8. For completeness there will also be a lecture on Eukaryotic Microorganisms

Immunology

  1. Immune System: Structure & Components
  2. Innate Immunity (1): First Line of Defence
  3. Innate Immunity (2): Induced Response
  4. Adaptive Immunity (1): Antigen Presentation
  5. Adaptive Immunity (2): T-cell/ B-cell activation & function
  6. Cytokines/Chemookines & Their Receptors: Role in coordinating the immune response
  7. Antibodies/Complement
  8. The Immune System & Disease: Asthma & Allergy  

Requisite

This course is only available to students enrolled in the Bachelor of Biomedical Science or Bachelor of Pharmacy (Honours) programs.


Assumed knowledge

HUBS1403 Biomedical Science Part 1 and HUBS1404 Human Bioscience Part 2 or equivalent


Assessment items

In Term Test: Mid semester tests *

Formal Examination: Final exam *

Tutorial / Laboratory Exercises: Laboratory reports *

Tutorial / Laboratory Exercises: Laboratory Skills

Tutorial / Laboratory Exercises: Presentations *

* This assessment has a compulsory requirement.


Compulsory Requirements

In order to pass this course, each student must complete ALL of the following compulsory requirements:

General Course Requirements:

  • Laboratory: Attendance Requirement - Students must attend a minimum number of these sessions. - This course has learning outcomes and assessment that relate to laboratory skills, so it is a requirement that you achieve a satisfactory level of attendance at laboratory sessions. Students who miss a laboratory session, and have grounds for special circumstances, will be provided alternative arrangements to meet these objectives & complete the assessment
  • Tutorial: Attendance Requirement - Students must attend a minimum number of these sessions. - Students who miss a tutorial session in which they are required/assigned to present and have grounds for special circumstances, will be provided alternative arrangements to meet these objectives & complete the assessment

Course Assessment Requirements:

  • Tutorial / Laboratory Exercises: Pass Requirement - Students must pass this assessment item to pass the course. - Students must pass the final examination and continual assessment (combination of 3 x in class exams, 2 x lab reports/essays, tutorial presentation(s)) to be able to pass the course overall.
  • Tutorial / Laboratory Exercises: Pass Requirement - Students must pass this assessment item to pass the course. - Students must pass the final examination and continual assessment (combination of 3 x in class exams, 2 x lab reports/essays, tutorial presentation(s)) to be able to pass the course overall.
  • Formal Examination: Pass Requirement - Students must pass this assessment item to pass the course. - Students must pass the final examination and continual assessment (combination of 3 x in class exams, 2 x lab reports/essays, tutorial presentation(s)) to be able to pass the course overall.
  • In Term Test: Pass Requirement - Students must pass this assessment item to pass the course. - Students must pass the final examination and continual assessment (combination of 3 x in class exams, 2 x lab reports/essays, tutorial presentation(s)) to be able to pass the course overall.

Contact hours

Callaghan

Laboratory

Face to Face On Campus 4 hour(s) per Week for 4 Weeks

Lecture

Face to Face On Campus 26 hour(s) per Term Full Term

Includes in-term examinations

Tutorial

Face to Face On Campus 1 hour(s) per Week for 12 Weeks