The University of Newcastle, Australia
Available in 2020

Course handbook

Description

Molecular genetics is at the centre of contemporary biology with DNA technology of ever increasing social relevance. This course will provide the core information required to understand molecular genetics and will examine the central roles of nucleic acids and proteins in the storage and flow of genetic information. The central dogma of molecular genetics will be examined in detail as well as outlining the mechanisms of transferring genetic information from one generation to the next. The replication, reading and the expression of genetic information will also be discussed in detail in this course. Questions to be addressed include: What is a gene? What are genes made of and where are genes located? How does a gene exert its effect? How is a gene mutated? How is a gene inherited? How are different genes maintained within a population?


Availability2020 Course Timetables

Callaghan

  • Semester 1 - 2020

Learning outcomes

On successful completion of the course students will be able to:

1. Describe the structure of nucleic acids: from single nucleotides through to whole genomes;

2. Explain the differences between the core molecular processes of replication, transcription and translation;

3. Explain how gene expression is regulated at multiple levels;

4. Compare and contrast the principles of Mendelian and population genetics;

5. Describe the role that mutation plays both in cancer genetics and in evolution;

6. Critically review scientific papers and general media presentations on issues related to molecular genetics;

7. Identify, gather, retrieve and analyse appropriate molecular genetics information via the internet;

8. Use online resources to interpret molecular genetics data.


Content

1. Gene structure: from single bases to whole genomes

2. The central dogma of molecular genetics

3. DNA replication

4. RNA transcription

5. Protein translation and modification

6. Gene expression regulation

7. Mutation and molecular evolution

8. Mendelian genetics

9. Population genetics

10. Cancer genetics.


Assumed knowledge

BIOL1001 and BIOL1002.


Assessment items

Formal Examination: Exam

Quiz: Quizzes - On-line

Written Assignment: Tutorial contribution Assignments


Contact hours

Callaghan

Lecture

Face to Face On Campus 3 hour(s) per Week for Full Term

Tutorial

Face to Face On Campus 1 hour(s) per Week for Full Term