Prof. Xu Zhang

Work Phone	(02) 4921 8906
Fax	(02) 4921 7311
Email	Xu.Zhang@newcastle.edu.au
Office	LS3-49, Life Sciences Building

Funding

Summary

Number of grants	34
Total funding	$5,137,426

For project grants received while at an institution other that the University of Newcastle, details are shown in italics.

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (4 grants)

Functional consequences of epigenetic repression of PIB5PA in melanoma$359,250

Project Team
Professor Xu Zhang, Dr Helen Rizos, Doctor Rick Thorne, Doctor Chen Chen Jiang
Funding Body
Cancer Council NSW
Scheme
Research Grant
Total Amount	Role
$359,250	Chief Investigator
Funding Start	Funding Finish
2013	2015
GNo:G1200386

Targeting PP2A to improve the therapeutic efficacy of mutant BRAF inhibitors in melanoma$359,250

Project Team
Professor Xu Zhang, Doctor Nikki Verrills, Doctor Chen Chen Jiang
Funding Body
Cancer Council NSW
Scheme
Research Grant
Total Amount	Role
$359,250	Chief Investigator
Funding Start	Funding Finish
2013	2015
GNo:G1200388

Leica TP 1020 Automatic Tissue Processor for histology applications$35,000

Project Team
Doctor Pradeep Tanwar, Professor Eileen McLaughlin, Professor Xu Zhang, Professor Robert Callister, Associate Professor Phillip Dickson, Professor Hubert Hondermarck, Doctor Jean-Marie Sontag, Associate Professor Dirk Van Helden, Doctor Doug Smith, Doctor Phil Jobling, Associate Professor Estelle Sontag, Associate Professor Paul Tooney, Doctor Susan Hua, Doctor Janet Holt, Doctor Jay Horvat, Doctor Liz Milward, Professor Adam McCluskey, Associate Professor Brett Nixon, Doctor Rebecca Lim, Associate Professor Alan Brichta
Funding Body
NHMRC (National Health & Medical Research Council)
Scheme
Equipment Grant
Total Amount	Role
$35,000	Investigator
Funding Start	Funding Finish
2013	2013
GNo:G1201185

Ultra-Low Temperature Cryogenic Freezer$24,596

Project Team
Doctor Jude Weidenhofer, Doctor Rick Thorne, Doctor Kathryn Skelding, Doctor Nikki Verrills, Doctor Pradeep Tanwar, Associate Professor Phillip Dickson, Doctor Murray Cairns, Professor Hubert Hondermarck, Professor Xu Zhang, Associate Professor Estelle Sontag, Doctor Chen Chen Jiang, Doctor Liz Milward, Doctor Jean-Marie Sontag, Associate Professor Paul Tooney, Doctor Severine Roselli, Doctor Matt Dun, Doctor Chris Dayas, Doctor Lin Kooi Ong, Associate Professor Dirk Van Helden, Mr Ben Copeland, Ms Gabrielle Briggs, Conjoint Professor Leonie Ashman, Professor John Rostas
Funding Body
NHMRC (National Health & Medical Research Council)
Scheme
Equipment Grant
Total Amount	Role
$24,596	Investigator
Funding Start	Funding Finish
2013	2013
GNo:G1201189

2012 (5 grants)

Targeting Histone Deacetylases to Overcome Resistance of BRAFV600E Melanoma Cells to Apoptosis$346,974

Project Team
Professor Xu Zhang, Conjoint Professor Peter Hersey, Dr Tao Liu, Doctor Chen Chen Jiang, Doctor Rick Thorne
Funding Body
NHMRC (National Health & Medical Research Council)
Scheme
Project Grant
Total Amount	Role
$346,974	Chief Investigator
Funding Start	Funding Finish
2012	2014
GNo:G1100133

The Hunter Cancer Biobank (HCB): Maximising community value through validation, annotation and distribution throughout NSW$294,301

Project Team
Professor John Forbes, Conjoint Professor Stephen Ackland, Professor Rodney Scott, Conjoint Associate Professor Barbara Young, Professor Hubert Hondermarck, Conjoint Professor Leonie Ashman, Professor Xu Zhang, Doctor Kelly Kiejda, Doctor Nikki Verrills, Doctor Jennette Sakoff, Ms Janine Lombard, Doctor Jude Weidenhofer, Doctor Pradeep Tanwar
Funding Body
Cancer Institute NSW
Scheme
Infrastructure Grants
Total Amount	Role
$294,301	Investigator
Funding Start	Funding Finish
2012	2014
GNo:G1200798

High-Resolution Isoelectric Phosphoprotein Signalling System for Signalling Research, Biomarker Validation and Drug Development – Equipment Grant$143,394

Project Team
Doctor Rick Thorne, Professor Xu Zhang, Professor Hubert Hondermarck, Conjoint Professor Stephen Ackland, Doctor Lisa Lincz, Doctor Jennette Sakoff, Conjoint Professor Leonie Ashman
Funding Body
Hunter Medical Research Institute
Scheme
Project Grant
Total Amount	Role
$143,394	Investigator
Funding Start	Funding Finish
2012	2012
GNo:G1200555

Microscopic illumination system for advanced fluorescent protein technology$34,000

Project Team
Doctor Rick Thorne, Professor Xu Zhang, Doctor Murray Cairns, Doctor Nikki Verrills, Doctor Charles De Bock, Doctor Jude Weidenhofer, Doctor Severine Roselli, Doctor Kathryn Skelding, Conjoint Professor Leonie Ashman, Professor Hubert Hondermarck
Funding Body
NHMRC (National Health & Medical Research Council)
Scheme
Equipment Grant
Total Amount	Role
$34,000	Investigator
Funding Start	Funding Finish
2012	2012
GNo:G1100983

A p53-Mediated Pro-Survival Signaling Pathway in Human Melanoma Progression and Resistance to Treatment$20,000

Project Team
Professor Xu Zhang, Doctor Rick Thorne, Doctor Chen Chen Jiang
Funding Body
University of Newcastle
Scheme
Near Miss Grant
Total Amount	Role
$20,000	Chief Investigator
Funding Start	Funding Finish
2012	2012
GNo:G1200672

2011 (6 grants)

Overcoming resistance of human metastatic melanoma to treatment$570,640

Project Team
Professor Xu Zhang
Funding Body
NHMRC (National Health & Medical Research Council)
Scheme
Research Fellowships
Total Amount	Role
$570,640	Chief Investigator
Funding Start	Funding Finish
2011	2015
GNo:G1000048

Targeting pro-survival mechanisms to sensitize human melanoma to immunotherapy$359,250

Project Team
Professor Xu Zhang, Doctor Ming Yang
Funding Body
Cancer Council NSW
Scheme
Research Program
Total Amount	Role
$359,250	Chief Investigator
Funding Start	Funding Finish
2011	2013
GNo:G1000379

Overcoming Resistance of Metastatic Melanoma to Treatment: 53 regulation of Mcl-1 via a microRNA-Mediated Pathway in Melanoma progression and Resistance to Chemotherapy$123,498

Project Team
Professor Xu Zhang
Funding Body
Cancer Institute NSW
Scheme
Career Development Fellowship
Total Amount	Role
$123,498	Chief Investigator
Funding Start	Funding Finish
2011	2014
GNo:G1000815

Regulation of BimS splicing in response of human melanoma cells to inhibition of BRAFVV600E$25,000

Project Team
Doctor Chen Chen Jiang, Professor Xu Zhang
Funding Body
Hunter Medical Research Institute
Scheme
Project Grant
Total Amount	Role
$25,000	Investigator
Funding Start	Funding Finish
2011	2011
GNo:G1000988

Targeting Pro-Survival Mechanisms to Sensitize Human Melanoma to Immunotherapy$25,000

Project Team
Professor Xu Zhang, Doctor Ming Yang
Funding Body
University of Newcastle
Scheme
Near Miss Grant
Total Amount	Role
$25,000	Chief Investigator
Funding Start	Funding Finish
2011	2011
GNo:G1001046

The Role of Phosphatidylinositol 4, 5-Bisphosphate 5-Phosphatase A (PIB5PA) in Regulation of PI3K/Akt Signalling in Melanoma$24,000

Project Team
Professor Xu Zhang, Doctor Chen Chen Jiang
Funding Body
Hunter Medical Research Institute
Scheme
Project Grant
Total Amount	Role
$24,000	Chief Investigator
Funding Start	Funding Finish
2011	2013
GNo:G1101121

2010 (4 grants)

Transcriptional regulation of the expression of Mcl-1 in melanoma cell under ER stress$144,300

Project Team
Conjoint Professor Peter Hersey, Professor Xu Zhang, Doctor Li Dong
Funding Body
NHMRC (National Health & Medical Research Council)
Scheme
Training (Postdoctoral) Fellowships - Australia-China Exchange Fellowships
Total Amount	Role
$144,300	Investigator
Funding Start	Funding Finish
2010	2013
GNo:G0190308

Melanoma Institute Australia Translational Research Program$58,405

Project Team
Professor Graham Mann, Professor John Thompson, Professor R Kefford, Clinical Professor Richard Scolyer, Professor Scott Menzies, Associate Professor Andrew Spillane, Conjoint Professor Peter Hersey, Dr Helen Rizos, Professor Xu Zhang, Professor Richard Christopherson
Funding Body
Cancer Institute NSW
Scheme
Translational Program Grant
Total Amount	Role
$58,405	Chief Investigator
Funding Start	Funding Finish
2010	2015
GNo:G1200975

Targeting Pro-Survival Mechanisms to Sensitize Human Melanoma to Immunotherapy$48,200

Project Team
Professor Xu Zhang
Funding Body
Cancer Institute NSW
Scheme
Research Innovation Grants
Total Amount	Role
$48,200	Chief Investigator
Funding Start	Funding Finish
2010	2010
GNo:G0190555

The role of micro-RNA-149 in Regulation of Mcl-1 in Human Melanoma under stress$20,000

Project Team
Doctor Chen Chen Jiang, Professor Xu Zhang
Funding Body
Hunter Children`s Research Foundation
Scheme
Research Grant
Total Amount	Role
$20,000	Investigator
Funding Start	Funding Finish
2010	2010
GNo:G0900189

2009 (4 grants)

Targeting adaptive mechanisms to endoplasmic reticulum stress in melanoma$491,250

Project Team
Professor Xu Zhang, Conjoint Professor Peter Hersey, Doctor Rick Thorne
Funding Body
NHMRC (National Health & Medical Research Council)
Scheme
Project Grant
Total Amount	Role
$491,250	Chief Investigator
Funding Start	Funding Finish
2009	2011
GNo:G0188902

Targeting p53 isoforms, delta-40p53 and p53-beta, to promote chemo-sensitivity in human melanoma$272,000

Project Team
Professor Xu Zhang, Conjoint Professor Peter Hersey, Doctor Kelly Kiejda
Funding Body
Cancer Council NSW
Scheme
Research Grant
Total Amount	Role
$272,000	Chief Investigator
Funding Start	Funding Finish
2009	2011
GNo:G0188913

Targeting p53 isoforms, delta-40p53 and p53-beta, to promote chemo-sensitivity in human melanoma$75,000

Project Team
Doctor Kelly Kiejda, Professor Xu Zhang, Conjoint Professor Peter Hersey
Funding Body
Cancer Australia
Scheme
Priority-driven Collaborative Cancer Research
Total Amount	Role
$75,000	Investigator
Funding Start	Funding Finish
2009	2010
GNo:G0188914

FACSAria$30,000

Project Team
Doctor Rick Thorne, Doctor Severine Roselli, Professor Xu Zhang, Dr Charles De Bock, Conjoint Professor Peter Hersey, Professor Gordon Burns
Funding Body
NHMRC (National Health & Medical Research Council)
Scheme
Equipment Grant
Total Amount	Role
$30,000	Investigator
Funding Start	Funding Finish
2009	2009
GNo:G0189846

2008 (1 grants)

Colibri high-performance LED illumination system for fluorescence live cell microscopy$23,225

Project Team
Doctor Rick Thorne, Dr Charles De Bock, Professor Xu Zhang, Doctor Lisa Lincz, Professor Gordon Burns, Conjoint Professor Peter Hersey, Associate Professor Dirk Van Helden, Conjoint Professor Keith Jones, Professor Roger Smith
Funding Body
NHMRC (National Health & Medical Research Council)
Scheme
Equipment Grant
Total Amount	Role
$23,225	Investigator
Funding Start	Funding Finish
2008	2008
GNo:G0188545

2007 (4 grants)

Characterization of p53 isoforms in human melanoma: do they play a role in chemoresistance?$75,000

Funding Body
Cure Cancer Australia Foundation
Scheme
Project Grant
Total Amount	Role
$75,000	Chief Investigator
Funding Start	Funding Finish
2007	2007
GNo:18105190

The role of p53 Isoforms in chemoresistances of human melanoma$20,000

Project Team
Professor Xu Zhang, Doctor Kelly Kiejda
Funding Body
Hunter Medical Research Institute
Scheme
Project Grant
Total Amount	Role
$20,000	Chief Investigator
Funding Start	Funding Finish
2007	2007
GNo:G0187239

The role of p53 isoforms in chemoresistance of human melanoma. $0

Funding Body
Newcastle Mater Misericordiae Hospital
Scheme
Small Grant
Total Amount	Role
$0	Chief Investigator
Funding Start	Funding Finish
2007	2007
GNo:18105231

molecular predictors of risk, progression and treatment response in melanoma$0

Funding Body
National Health & Medical Research Council
Scheme
Program Grant
Total Amount	Role
$0	Investigator
Funding Start	Funding Finish
2007	2007
GNo:18105827

2006 (1 grants)

PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143

Project Team
Professor Pablo Moscato, Professor Rodney Scott, Professor John Rostas, Professor John Forbes, Conjoint Professor Peter Hersey, Conjoint Professor Stephen Ackland, Conjoint Professor Wayne Smith, Emeritus Professor Peter Dunkley, Conjoint Professor Leonie Ashman, Professor John Attia, Associate Professor Phillip Dickson, Doctor Liz Milward, Professor Alistair Sim, Associate Professor Paul Tooney, Doctor Regina Berretta, Associate Professor David Sibbritt, Conjoint Professor Chris Levi, Professor Xu Zhang, Conjoint Associate Professor Patricia Crock, Conjoint Associate Professor Jeannette Lechner-Scott
Funding Body
University of Newcastle
Scheme
Priority Research Centre
Total Amount	Role
$621,143	Investigator
Funding Start	Funding Finish
2006	2013
GNo:G0186919

2005 (4 grants)

Overcoming resistance of human melanoma to chemotherapy$492,750

Project Team
Conjoint Professor Peter Hersey, Professor Xu Zhang, Dr John Allen
Funding Body
NHMRC (National Health & Medical Research Council)
Scheme
Project Grant
Total Amount	Role
$492,750	Investigator
Funding Start	Funding Finish
2005	2007
GNo:G0183933

PULSE Young Medical Researcher of the Year Award$5,000

Project Team
Professor Xu Zhang
Funding Body
Hunter Medical Research Institute
Scheme
Young Medical Researcher of the Year Award
Total Amount	Role
$5,000	Chief Investigator
Funding Start	Funding Finish
2005	2005
GNo:G0184902

Overcoming Resistance of Melanoma to Chemotherapy$0

Funding Body
National Health & Medical Research Council
Scheme
Project
Total Amount	Role
$0	Chief Investigator
Funding Start	Funding Finish
2005	2007
GNo:18105841

Overcoming Resistance of Melanoma to Chemotherapy: Are Melanoma Stem Cells Key Targets? $0

Funding Body
Cancer Institute NSW
Scheme
Career Development and Support Fellowship
Total Amount	Role
$0	Chief Investigator
Funding Start	Funding Finish
2005	2007
GNo:18105807

2003 (1 grants)

Regulation of TNF Apoptosis Inducing Ligand (TRAIL) Receptor Expression in Human Melanoma Cells.$17,000

Project Team
Conjoint Professor Peter Hersey, Professor Xu Zhang
Funding Body
Hunter Medical Research Institute
Scheme
Research Grant
Total Amount	Role
$17,000	Investigator
Funding Start	Funding Finish
2003	2003
GNo:G0182640

The University of Newcastle, Australia