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Dr Simon Keely

Work Phone (02) 4042 0229
Fax (02) 4042 0026
Email
Office Rm 2413, Level 2 Eas, Life Sciences Building (callaghan) Hunter Medical Research Institute (hmri)

Highlighted Publications

Year Citation Link
2009 KEELY S, GLOVER L, MACMANUS C, CAMPBELL E, SCULLY M, FURUTA G, COLGAN S, 'Selective induction of integrin beta1 by hypoxia-inducible factor: implications for wound healing.', The FASEB Journal, 23 1338-1346 (2009) [C1]
2008 ROBINSON A, KEELY S, KARHAUSEN J, GERICH M, FURUTA G, COLGAN S, 'Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition.', Gastroenterology, 134 346-348 (2008) [C1]
2010 KEELY S, GLOVER L, WEISSMUELLER T, MACMANUS C, FILLON S, FENNIMORE B, COLGAN S, 'Hypoxia-inducible factor-dependent regulation of platelet-activating factor receptor as a route for gram-positive bacterial translocation across epithelia', Molecular Biology of the Cell, 21 538-546 (2010) [C1]
2012 Keely Simon, Talley Nicholas Joseph, Hansbro Philip Michael, 'Pulmonary-intestinal cross-talk in mucosal inflammatory disease', Mucosal Immunology, 5 7-18 (2012) [C1] Nova
2011 KOMINSKY D, KEELY S, MACMANUS C, GLOVER L, SCULLY M, COLLINS C, BOWERS B, CAMPBELL E, COLGAN S, 'An Endogenously Anti-Inflammatory Role for Methylation in Mucosal Inflammation Identified through Metabolite Profiling.', Journal of Immunology, 186 6505-6514 (2011) [C1]
2005 KEELY S, ATVINDER R, WILSON C, CARMICHAEL A, CARRINGTON S, CORFIELD A, HADDLETON D, BRAYDEN D, 'In vitro and ex vivo intestinal tissue models to measure mucoadhesion of poly (methacrylate) and N-trimethylated chitosan polymers.', Pharmaceutical Research, 22 38-49 (2005) [C1]
2009 KEELY S, RYAN S, HADDLETON D, LIMER A, MANTOVANI G, MURPHY E, BRAYDEN D, 'Dexamethasone-pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers.', Journal of Controlled Release, 135 35-43 (2009) [C1]

Publications

For items published while at an institution other that the University of Newcastle, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Journal Articles (16 outputs)

Refereed Article in a Scholarly Journal (C1) (16 outputs)

Year Citation Link
2012 Keely Simon, Kelly Caleb, Weissmueller Thomas, Burgess Adrianne, Wagner Brandie, Robertson Charles E, Harris J Kirk, Colgan Sean P, 'Activated fluid transport regulates bacterial-epithelial interactions and significantly shifts the murine colonic microbiome', Gut Microbes, 3 250-60 (2012) [C1]
2012 Keely Simon, Talley Nicholas Joseph, Hansbro Philip Michael, 'Pulmonary-intestinal cross-talk in mucosal inflammatory disease', Mucosal Immunology, 5 7-18 (2012) [C1] Nova
2011 KOMINSKY D, KEELY S, MACMANUS C, GLOVER L, SCULLY M, COLLINS C, BOWERS B, CAMPBELL E, COLGAN S, 'An Endogenously Anti-Inflammatory Role for Methylation in Mucosal Inflammation Identified through Metabolite Profiling.', Journal of Immunology, 186 6505-6514 (2011) [C1]
2011 MACMANUS C, CAMPBELL E, KEELY S, ADRIENNE B, KOMINSKY D, COLGAN S, 'Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization', The FASEB Journal, 25 1856-1864 (2011) [C1]
2011 Keely Simon, Feighery Linda, Campion Deirdre P, O'Brien Leah, Brayden David J, Baird Alan W, 'Chloride-led disruption of the intestinal mucous layer impedes salmonella invasion: Evidence for an 'enteric tear' mechanism', Cellular Physiology and Biochemistry, 28 743-752 (2011) [C1]
2010 CAMPBELL E, MACMANUS C, KOMINSKY D, KEELY S, GLOVER L, SCULLY M, BRUYNINCKX W, COLGAN S, 'Resolvin E1-induced Intestinal Alkaline Phosphatase Promotes Resolution of Inflammation through LPS detoxification.', Proceedings of the National Academy of Sciences of USA, 107 4298-4303 (2010) [C1]
2010 KEELY S, GLOVER L, WEISSMUELLER T, MACMANUS C, FILLON S, FENNIMORE B, COLGAN S, 'Hypoxia-inducible factor-dependent regulation of platelet-activating factor receptor as a route for gram-positive bacterial translocation across epithelia', Molecular Biology of the Cell, 21 538-546 (2010) [C1]
2009 KEELY S, GLOVER L, MACMANUS C, CAMPBELL E, SCULLY M, FURUTA G, COLGAN S, 'Selective induction of integrin beta1 by hypoxia-inducible factor: implications for wound healing.', The FASEB Journal, 23 1338-1346 (2009) [C1]
2009 KEELY S, RYAN S, HADDLETON D, LIMER A, MANTOVANI G, MURPHY E, BRAYDEN D, 'Dexamethasone-pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers.', Journal of Controlled Release, 135 35-43 (2009) [C1]
2008 BOLAND T, HAYES L, SWEENEY T, CALLANAN J, BAIRD A, KEELY S, CROSBY T, 'The effects of cobalt and iodine supplementation of the pregnant ewe diet on immunoglobulin G, vitamin E, T-3 and T-4 levels in the progeny.', Animal: the international journal of animal biosciences, 2 197-206 (2008) [C1]
2008 FANNING R, CAMPION D, COLLINS C, KEELY S, BRIGGS L, O'CONNOR J, CAREY M, 'A comparison of the inhibitory effects of bupivacaine and levobupivacaine on isolated human pregnant myometrium contractility.', Anesthesia and Analgesia, 107 1303-1307 (2008) [C1]
2008 FEIGHERY L, SMYTH A, KEELY S, BAIRD A, O'CONNOR W, CALLANAN J, BRAYDEN D, 'Increased intestinal permeability in rats subjected to traumatic frontal lobe percussion brain injury.', Journal of Trauma: Injury Infection and Critical Care, 64 131-137 (2008) [C1]
2008 KEELY S, RAWLINSON L, HADDLETON D, BRAYDEN D, 'Tertiary Amino-Containing Polymethacrylate Polymer Protects Mucus-Covered Intestinal Epithelial Monolayers Against Pathogenic Challenge', Pharmaceutical Research, 25 1193-1201 (2008) [C1]
2008 ROBINSON A, KEELY S, KARHAUSEN J, GERICH M, FURUTA G, COLGAN S, 'Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition.', Gastroenterology, 134 346-348 (2008) [C1]
2006 LIMER A, ATTVINDER R, SAN MIGUEL V, PEINADO C, KEELY S, FITZPATRICK E, CARRINGTON S, BRAYDEN D, HADDLETON D, 'Fluorescently tagged star polymers by living radical polymerisation for mucoadhesion and bioadhesion.', Reactive and Functional Polymers, 66 51-64 (2006) [C1]
2005 KEELY S, ATVINDER R, WILSON C, CARMICHAEL A, CARRINGTON S, CORFIELD A, HADDLETON D, BRAYDEN D, 'In vitro and ex vivo intestinal tissue models to measure mucoadhesion of poly (methacrylate) and N-trimethylated chitosan polymers.', Pharmaceutical Research, 22 38-49 (2005) [C1]
Show 13 more

Conference Publication (10 outputs)

Extract of Paper (E3) (10 outputs)

Year Citation Link
2012 Chaney Ciaran, Minahan Kyra Lee, Mateer Sean, Nolan Gavin Michael, Talley Nicholas Joseph, Keely Simon, 'Hypoxic regulation of β1 integrin during mucosal wound healing', Journal of Gastroenterology and Hepatology, Adelaide, S.A. (2012) [E3]
2012 Farrell Kristen Elise, Keely Simon, Graham Brett Anthony, Minahan Kyra Lee, Madden Jessica Frances, Callister Robert John, 'Spinal cord signalling in a mouse model of inflammatory bowel disease', Journal of Gastroenterology and Hepatology, Adelaide, SA (2012) [E3]
2012 Keely Simon, Baird Alan W, Colgan Sean, 'Epithelial HIF-1 ¿¿ is critical to the protective action of prolyl hydroxylase inhibition in a murine model of inflammatory bowel disease', Journal of Gastroenterology and Hepatology, Adelaide, S.A. (2012) [E3]
2012 Keely Simon, Baird Alan, Kominsky Douglas, McNamee Eoin N, Hansbro Philip Michael, Shalwitz Robert A, Colgan Sean P, 'Immune modulation by prolyl hydroxylase inhibition contributes to the prevention of endotoxemia in a murine model of inflammatory bowel disease', FASEB Journal, San Diego, California (2012) [E3]
2012 Mateer Sean, Hansbro Philip Michael, Nolan Gavin Michael, Chaney Ciaran, Minahan Kyra Lee, Keely Simon, 'Development of pulmonary inflammation and altered lung function in a mouse model of colitis', Journal of Gastroenterology and Hepatology, Adelaide, S.A. (2012) [E3]
2012 Nolan Gavin Michael, Minahan Kyra Lee, Farrell Kristen Elise, Chaney Ciaran, Mateer Sean, Talley Nicholas Joseph, Keely Simon, 'Hypoxia-inducible factor-1 α promotes mucosal protection in colitis via the IL-12 signalling pathway', Journal of Gastroenterology and Hepatology, Adelaide, S.A. (2012) [E3]
2011 Campbell E, Macmanus C, Kominsky D, Keely Simon, Glover L, Bowers B, Scully M, Bruyninckx W, Colgan S, 'Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification', Inflammatory Bowel Diseases, Hollywood, Florida (2011) [E3]
2011 Keely Simon, Baird A, Kominsky D, Campbell E, Burgess A, Colgan S, 'HIF prolyl hydroxylase inhibition reverses disease symptoms in established TNBS colitis', Inflammatory Bowel Diseases, Hollywood, Florida (2011) [E3]
2011 Kominsky D, Keely Simon, Campbell E, Christopher M, Scully M, Collins C, Bowers B, Colgan S, 'A central role of methylation in mucosal inflammation', Inflammatory Bowel Diseases, Hollywood, Florida (2011) [E3]
2011 Kominsky Douglas, Keely Simon, Macmanus Christopher, Glover Louise, Scully Melanie, Collins Colm, Bowers Britelle, Campbell Eric, Colgan Sean, 'Cellular methylation plays an anti-inflammatory role in Mucosal Inflammation', Inflammatory Bowel Diseases, Hollywood, Florida (2011) [E3]
Show 7 more