Dr Mark Baker

Work Phone	(02) 4921 7880
Fax	(02) 4921 6308
Email	Mark.Baker@newcastle.edu.au
Office	LS4-42, Life Sciences

Highlighted Publications

Year	Citation	Nova
2011	Baker Mark Andrew, Smith Nathan Druery, Hetherington Louise, Pelzing Matthias, Condina Mark R, Aitken Robert John, 'Use of titanium dioxide to find phosphopeptide and total protein changes during epididymal sperm maturation', Journal of Proteome Research, 10 1004-1017 (2011) [C1]
2010	Baker Mark Andrew, Smith Nathan Druery, Hetherington Louise, Taubman Kristy, Graham Mark E, Robinson Phillip J, Aitken Robert John, 'Label-free quantitation of phosphopeptide changes during rat sperm capacitation', Journal of Proteome Research, 9 718-729 (2010) [C1]
2009	Baker Mark Andrew, Hetherington Louise, Curry Benjamin John, Aitken Robert John, 'Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa: Its implications during capacitation', Developmental Biology, 333 57-66 (2009) [C1]
2008	Aitken Robert John, Baker Mark Andrew, Doncel Gustavo F, Matzuk Martin M, Mauck Christine K, Harper Michael J K, 'As the world grows: Contraception in the 21st century', Journal of Clinical Investigation, 118 1330-1343 (2008) [C1]

Publications

For items published while at an institution other that the University of Newcastle, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapters In A Book (3 outputs)

Chapter in A1 Book (B1) (3 outputs)

Year	Citation	Nova
2012	Aitken Robert John, De Iuliis Geoffry Nunzio, Baker Mark Andrew, 'Direct methods for the detection of reactive oxygen species in human semen samples', Studies on Men's Health and Fertility, Springer, New York, 275-299 (2012) [B1]
2010	Aitken Robert John, Baker Mark Andrew, De Iuliis Geoffry Nunzio, Nixon Brett, 'New insights into sperm physiology and pathology', Fertility Control, Springer, Berlin, 99-115 (2010) [B1]
2007	Aitken Robert John, Roman Shaun Daryl, Baker Mark Andrew, De Iuliis Geoffry Nunzio, 'Redox regulation of DNA damage in the male germ line', Male-Mediated Developmental Toxicity, Royal Society of Chemistry, London, United Kingdom, 197-209 (2007) [B1]

Journal Articles (44 outputs)

Refereed Article in a Scholarly Journal (C1) (42 outputs)

Year	Citation	Nova
2012	Aitken Robert John, Whiting Sara Jayne, De Iuliis Geoffry Nunzio, McClymont Samantha Louise, Mitchell Lisa Ann, Baker Mark Andrew, 'Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase', Journal of Biological Chemistry, 287 33048-33060 (2012) [C1]
2012	Baker Mark Andrew, Hetherington Louise, Weinberg Anita Shandelle, Naumovski Nenad, Velkov Tony, Pelzing Matthias, Dolman Sebastiaan, Condina Mark R, Aitken Robert John, 'Analysis of phosphopeptide changes as spermatozoa acquire functional competence in the epididymis demonstrates changes in the post-translational modification of Izumo1', Journal of Proteome Research, 11 5252-5264 (2012) [C1]
2012	Baker Mark Andrew, Nixon Brett, Naumovski Nenad, Aitken Robert John, 'Proteomic insights into the maturation and capacitation of mammalian spermatozoa', Systems Biology in Reproductive Medicine, 58 211-217 (2012) [C1]
2012	Huang Johnny X, Azad Mohammad A K, Yuriev Elizabeth, Baker Mark Andrew, Nation Roger L, Li Jian, Cooper Matthew A, Velkov Tony, 'Molecular characterization of lipopolysaccharide binding to human ¿¿-1-acid glycoprotein', Journal of Lipids, - 1-15 (2012) [C1]
2012	Huang Johnny X, Cooper Matthew A, Baker Mark Andrew, Azad Mohammad A K, Nation Roger L, Li Jian, Velkov Tony, 'Drug-binding energetics of human alpha-1-acid glycoprotein assessed by isothermal titration calorimetry and molecular docking simulations', Journal of Molecular Recognition, 25 642-656 (2012) [C1]
2012	Redgrove Kate Amanda, Nixon Brett, Baker Mark Andrew, Hetherington Louise, Baker Gordon, Liu De-Yi, Aitken Robert John, 'The molecular chaperone HSPA2 plays a key role in regulating the expression of sperm surface receptors that mediate sperm-egg recognition', Plos One, 7 1-16 (2012) [C1]
2011	Baker Mark Andrew, 'The ‘omics revolution and our understanding of sperm cell biology', Asian Journal of Andrology, 13 6-10 (2011) [C1]
2011	Baker Mark Andrew, Smith Nathan Druery, Hetherington Louise, Pelzing Matthias, Condina Mark R, Aitken Robert John, 'Use of titanium dioxide to find phosphopeptide and total protein changes during epididymal sperm maturation', Journal of Proteome Research, 10 1004-1017 (2011) [C1]
2011	Dun Matthew Desmond, Smith Nathan Druery, Baker Mark Andrew, Lin Minjie, Aitken Robert John, Nixon Brett, 'The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction', Journal of Biological Chemistry, 286 36875-36887 (2011) [C1]
2010	Baker Mark Andrew, Reeves Gabi Monika, Hetherington Louise, Aitken Robert John, 'Analysis of proteomic changes associated with sperm capacitation through the combined use of IPG-strip pre-fractionation followed by RP chromatography LC-MS/MS analysis', Proteomics, 10 482-495 (2010) [C1]
2010	Baker Mark Andrew, Smith Nathan Druery, Hetherington Louise, Taubman Kristy, Graham Mark E, Robinson Phillip J, Aitken Robert John, 'Label-free quantitation of phosphopeptide changes during rat sperm capacitation', Journal of Proteome Research, 9 718-729 (2010) [C1]
2009	Baker Mark Andrew, Aitken Robert John, 'Proteomic insights into spermatozoa: Critiques, comments and concerns', Expert Review of Proteomics, 6 691-705 (2009) [C1]
2009	Baker Mark Andrew, Hetherington Louise, Curry Benjamin John, Aitken Robert John, 'Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa: Its implications during capacitation', Developmental Biology, 333 57-66 (2009) [C1]
2009	Ewen Katherine Amme, Baker Mark Andrew, Wilhelm Dagmar, Aitken Robert John, Koopman Peter, 'Global survey of protein expression during gonadal sex determination in mice', Molecular & Cellular Proteomics, 8 2624-2641 (2009) [C1]
2008	Aitken Robert John, Baker Mark Andrew, 'The role of proteomics in understanding sperm cell biology', International Journal of Andrology, 31 295-302 (2008) [C1]
2008	Aitken Robert John, Baker Mark Andrew, Doncel Gustavo F, Matzuk Martin M, Mauck Christine K, Harper Michael J K, 'As the world grows: Contraception in the 21st century', Journal of Clinical Investigation, 118 1330-1343 (2008) [C1]
2008	Aitken Robert John, Hughes Louise Mary, Griffith Renate, Baker Mark Andrew, 'Bridging the gap between male and female fertility control; contraception-on-demand', Contraception, 78 S28-S35 (2008) [C1]
2008	Baker Mark Andrew, Hetherington Louise, Reeves Gabi Monika, Aitken Robert John, 'The mouse sperm proteome characterized via IPG strip prefractionation and LC-MS/MS identification', Proteomics, 8 1720-1730 (2008) [C1]
2008	Baker Mark Andrew, Hetherington Louise, Reeves Gabi Monika, Muller Jorg, Aitken Robert John, 'The rat sperm proteome characterized via IPG strip prefractionation and LC-MS/MS identification', Proteomics, 8 2312-2321 (2008) [C1]
2008	Mitchell Lisa Ann, Nixon Brett, Baker Mark Andrew, Aitken Robert John, 'Investigation of the role of SRC in capacitation-associated tyrosine phosphorylation of human spermatozoa', Molecular Human Reproduction, 14 235-243 (2008) [C1]
2007	Aitken Robert John, Baker Mark Andrew, 'The role of proteomics in understanding sperm cell biology', International Journal of Andrology, 30 1-8 (2007) [C1]
2007	Aitken Robert John, Nixon Brett, Lin Minjie, Koppers Adam John, Lee Yun Hwa, Baker Mark Andrew, 'Proteomic changes in mammalian spermatozoa during epididymal maturation', Asian Journal of Andrology, 9 554-564 (2007) [C1]
2007	Baker Mark Andrew, Reeves Glenn E, Hetherington Louise, Muller J, Baur I, Aitken Robert John, 'Identification of gene products present in Triton X-100 soluble and insoluble fractions of human spermatozoa lysates using LC-MS/MS analysis', Proteomics Clinical Applications, 1 524-532 (2007) [C1]
2006	Aitken Robert John, Baker Mark Andrew, 'Oxidative stress, sperm survival and fertility control', Molecular and Cellular Endocrinology, 250 66-69 (2006) [C1]
2006	Baker Mark Andrew, Hetherington Louise, Aitken Robert John, 'Identification of SRC as a key PKA-stimulated tyrosine kinase involved in the capacitation-associated hyperactivation of murine spermatozoa', Journal of Cell Science, 119 3182-3192 (2006) [C1]
2006	Lin Minjie, Lee Yun Hwa, Xu Weiran, Baker Mark Andrew, Aitken Robert John, 'Ontogeny of tyrosine phosphorylation-signaling pathways during spermatogenesis and epididymal maturation in the mouse', Biology of Reproduction, 75 588-597 (2006) [C1]
2005	Baker Mark Andrew, Aitken Robert John, 'Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility', Reproductive Biology and Endocrinology, 3 9 (2005) [C1]
2005	Baker Mark Andrew, Krutskikh Anton, Curry Benjamin John, Hetherington Louise, Aitken Robert John, 'Identification of cytochrome-b5 reductase as the enzyme responsible for NADH-dependent lucigenin chemiluminescence in human spermatozoa', Biology of Reproduction, 73 334-342 (2005) [C1]
2005	Baker Mark Andrew, Witherdin Roxanne Frances, Hetherington Louise, Cunningham Kelly Anne, Aitken Robert John, 'Identification of post-translational modifications that occur during sperm maturation using difference in two-dimensional gel electrophoresis', Proteomics, 5 1003-1012 (2005) [C1]
2004	Aitken Robert John, Baker Mark Andrew, 'Oxidative stress and male reproductive biology', Reproduction, Fertility and Development, 16 581-588 (2004) [C1]
2004	Aitken Robert John, Baker Mark Andrew, O'Bryan Moira, 'Shedding Light on Chemiluminescence: The Application of Chemiluminescence in Diagnostic Andrology', Journal of Andrology, 25 455-465 (2004) [C1]
2004	Aitken Robert John, Ryan Angela Louise, Baker Mark Andrew, McLaughlin Eileen Anne, 'Redox activity associated with the maturation and capacitation of mammalian spermatozoa', Free Radical Biology and Medicine, 36 994-1010 (2004) [C1]
2004	Baker Mark Andrew, Aitken Robert John, 'The importance of redox regulated pathways in sperm cell biology', Molecular and Cellular Endocrinology, 216 47-54 (2004) [C1]
2004	Baker Mark Andrew, Hetherington Louise, Ecroyd Heath William, Roman Shaun Daryl, Aitken Robert John, 'Analysis of the mechanism by which calcium negatively regulates the tyrosine phoshorylation cascade associated with sperm capacitation', Journal of Cell Science, 117 211-222 (2004) [C1]
2004	Baker Mark Andrew, Krutskikh Anton, Curry Benjamin John, McLaughlin Eileen Anne, Aitken Robert John, 'Identification of Cytochrome P450-Reductase as the Enzyme Responsible for NADPH-Dependent Lucigenin and Tetrazolium Salt Reduction in Rat Epididymal Sperm Preparations', Biology of Reproduction, 71 307-318 (2004) [C1]
2004	Sidhu K S, Mate Karen Elizabeth, Gunasekera T, Veal D, Hetherington Louise, Baker Mark Andrew, Aitken Robert John, Rodger John Cameron, 'A flow cytometric assay for global estimation of tyrosine phosphorylation associated with capacitation of spermatozoa from two marsupial species, the tammar wallaby (Macropus eugenii) and the brushtail possum (Trichosurus vulpecula)', Reproduction, 127 95-103 (2004) [C1]
2003	Aitken Robert John, Baker Mark Andrew, Sawyer Dennis Earl, 'Oxidative stress in the male germ line and its role in the aetiology of male infertility and genetic disease', Reproductive BioMedicine, 7 65-70 (2003) [C1]
2003	Aitken Robert John, Ryan Angela Louise, Curry Benjamin John, Baker Mark Andrew, 'Multiple forms of redox activity in populations of human spermatozoa', Molecular Human Reproduction, 9 645-661 (2003) [C1]
2003	Baker Mark Andrew, Krutskikh Anton, Aitken Robert John, 'Biochemical entities involved in reactive oxygen species generation by human spermatozoa', Protoplasma 145-151 (2003) [C1]
2003	Baker Mark Andrew, Lewis Beverley, Hetherington Louise, Aitken Robert John, 'Development of the Signalling Pathways Associated With Sperm Capacitation During Epididymal Maturation', Molecular Reproduction and Development 446-457 (2003) [C1]
2002	BAKER M A, GRUBB D, LAWEN A, 'Didemnin B induces apoptosis in proliferating but not resting peripheral blood mononuclear cells', Apoptosis: an international journal on programmed cell death, 407-412 (2002) [C1]
2002	Aitken Robert John, Baker Mark Andrew, 'Reactive oxygen species generation by human spermatozoa: a continuing enigma', International Journal of Andrology, 25 191-194 (2002) [C1]

Non Refereed Article in a Scholarly Journal (C2) (1 outputs)

Year	Citation	Nova
2012	Aitken Robert John, De Iuliis Geoffry Nunzio, Gibb Z, Baker Mark Andrew, 'The Simmet lecture: New horizons on an old landscape - oxidative stress, DNA damage and apoptosis in the male germ line', Reproduction in Domestic Animals, 47 7-14 (2012) [C2]

Non Refereed Article in a Professional Journal (C3) (1 outputs)

Year	Citation	Nova
2011	Aitken Robert John, Baker Mark Andrew, 'Cell biology of human spermatozoa: Lessons from the Proteome', Australian Biochemist, 42 12-15 (2011) [C3]

Conference Publication (11 outputs)

Extract of Paper (E3) (11 outputs)

Year	Citation	Nova
2012	Kongmanas K, Sugeng C, Souda P, Faull K, Kitajima K, Aitken Robert John, Berger T, Baker Mark Andrew, Whitelegge J, Tanphaichitr N, 'Proteomic analysis of sperm anterior head plasma membrane: Unfolding the molecular components underlying sperm-egg interaction', Reproduction in Domestic Animals, Vancouver, Canada (2012) [E3]
2012	Nixon Brett, Redgrove Kate Amanda, Baker Mark Andrew, Aitken Robert John, 'The role of molecular chaperones in regulating human sperm-egg recognition', Abstracts. The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2012, Gold Coast, QLD (2012) [E3]
2008	Baker Mark Andrew, Hetherington Louise, Reeves Gabi Monika, Smith Nathan Druery, Aitken Robert John, 'Comparative and phospho proteomics: Identification of protein changes during sperm maturation', Proceedings of 41st Annual Meeting of the Society for the Study of Reproduction. "Reproductive Biology: Basic Discoveries that Affect Our Lives", Kailua-Kona, Hawaii (2008) [E3]
2007	Baker Mark Andrew, 'The proteomic analysis of sperm maturation', Gordon Research Conferences: Fertilization & Activation of Development. Program, Plymouth, UK (2007) [E3]
2006	Aitken Robert John, Baker Mark Andrew, Lee Yun Hwa, Lin Minjie, Nixon Brett, 'Proteomic Changes in Mouse Spermatozoa During Epididymal Transit', Abstracts, Chatel-Guyon, Auvergne, France (2006) [E3]
2006	Baker Mark Andrew, Curry Benjamin John, Aitken Robert John, 'Inactivation of C-ABL Via PKA During Capacitation of Mouse Spermatozoa', Book of Abstracts, Lorne, Victoria, Australia (2006) [E3]
2006	Baker Mark Andrew, Reeves Gabi Monika, Aitken Robert John, 'New approaches towards the proteomic analysis of the human spermatozoon', Book of Abstracts, Chicago, Illinois (2006) [E3]
2006	Baker Mark Andrew, Reeves Glenn E, Aitken Robert John, 'New Approaches Towards the Proteomic Analysis of the Human Spermatozoon', Book of Abstracts, Lorne, Victoria, Australia (2006) [E3]
2003	Baker Mark Andrew, Hetherington Louise, Ecroyd Heath William, Roman Shaun Daryl, Aitken Robert John, 'Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation', ComBio Combined Conference Abstracts, Melbourne (2003) [E3]
2002	Aitken Robert John, Baker Mark Andrew, Krutskikh A, 'Oxidative stress and redox regulation in the epididymis', Epididymis III. Third International Conference on the Epididymis., Charlottesville, Virginia, USA (2002) [E3]
2002	Baker Mark Andrew, Krutskikh A, Aitken Robert John, 'Redox regulation of sperm function', Proceedings of the Thirty-third annual Conference of the Society for Reproductive Biology, Adelaide, SA (2002) [E3]

The University of Newcastle, Australia