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A/Prof. Dirk Van Helden

Work Phone (02) 4921 5623
Fax (02) 4921 7406
Email
Office MS405, Medical Sciences

Highlighted Publications

Year Citation Link
2002 Zhao Jun, Van Helden Dirk Ferdinand, 'ATP-induced endothelium-independent enhancement of lymphatic vasomotion in guinea-pig mesentery involves P2x and P2y receptors', British Journal of Pharmacology, 137 477-487 (2002) [C1] Nova
2003 Van Helden Dirk Ferdinand, Imtiaz Mohammad Sahariq, 'Ca2+ phase waves: a basis for cellular pacemaking and long-range synchronicity in the guinea-pig gastric pylorus', The Journal of Physiology, 548.1 271-296 (2003) [C1] Nova
2006 Imtiaz Mohammad Sahariq, Katnik C P, Smith D W, Van Helden Dirk Ferdinand, 'Role of voltage-dependent modulation of store Ca2+ release in synchronization of Ca2+ oscillations', Biophysical Journal, 90 1-23 (2006) [C1] Nova
2005 Odell Adam Francis, Scott Judith Louise, Van Helden Dirk Ferdinand, 'Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4', Journal of Biological Chemistry, 280 37974-37987 (2005) [C1] Nova

Publications

For items published while at an institution other that the University of Newcastle, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Journal Articles (30 outputs)

Refereed Article in a Scholarly Journal (C1) (30 outputs)

Year Citation Link
2012 De Oliveira Ramatis, Gravina Fernanda Sbaraini, Lim Rebecca, Brichta Alan Martin, Callister Robert John, Van Helden Dirk Ferdinand, 'Heterogeneous responses to antioxidants in noradrenergic neurons of the Locus coeruleus indicate differing susceptibility to free radical content', Oxidative Medicine and Cellular Longevity, 2012 820285 (2012) [C1]
2011 De Oliveira Ramatis, Gravina Fernanda Sbaraini, Lim Rebecca, Brichta Alan Martin, Callister Robert John, Van Helden Dirk Ferdinand, 'Developmental changes in pacemaker currents in mouse locus coeruleus neurons', Brain Research, 1425 27-36 (2011) [C1] Nova
2011 Gravina Fernanda Sbaraini, Jobling Phillip, Kerr Karen Patricia, De Oliveira Ramatis, Parkington H C, Van Helden Dirk Ferdinand, 'Oxytocin depolarizes mitochondria in isolated myometrial cells', Experimental Physiology, 96 949-956 (2011) [C1] Nova
2011 Laver Derek Rowland, Van Helden Dirk Ferdinand, 'Three independent mechanisms contribute to tetracaine inhibition of cardiac calcium release channels', Journal of Molecular and Cellular Cardiology, 51 357-369 (2011) [C1]
2011 Saul Megan E, Thomas Paul A, Dosen Peter John, Isbister Geoffrey Kennedy, O'Leary Margaret A, Whyte Ian Macgregor, McFadden Sally Anne, Van Helden Dirk Ferdinand, 'A pharmacological approach to first aid treatment for snakebite', Nature Medicine, 17 809-811 (2011) [C1]
2010 De Oliveira Ramatis, Graham Brett Anthony, Howlett Marcus Christian, Gravina Fernanda Sbaraini, Oliveira Max William, Imtiaz Mohammad Sahariq, Callister Robert John, Lim Rebecca, Brichta Alan Martin, Van Helden Dirk Ferdinand, 'Ketamine anesthesia helps preserve neuronal viability', Journal of Neuroscience Methods, 189 230-232 (2010) [C1] Nova
2010 De Oliveira Ramatis, Howlett Marcus Christian, Gravina Fernanda Sbaraini, Imtiaz Mohammad Sahariq, Callister Robert John, Brichta Alan Martin, Van Helden Dirk Ferdinand, 'Pacemaker currents in mouse locus coeruleus neurons', Pacemaker currents in mouse locus coeruleus neurons, 170 166-177 (2010) [C1] Nova
2010 Gravina Fernanda Sbaraini, Parkington H C, Kerr Karen Patricia, De Oliveira Ramatis, Jobling Phillip, Coleman H A, Sandow S L, Davies M M, Imtiaz M S, Van Helden Dirk Ferdinand, 'Role of mitochondria in contraction and pacemaking in the mouse uterus', British Journal of Pharmacology, 161 1375-1390 (2010) [C1] Nova
2010 Imtiaz Mohammad S, Von Der Weid Pierre-Yves, Laver Derek Rowland, Van Helden Dirk Ferdinand, 'SR Ca2+ store refill-a key factor in cardiac pacemaking', Journal of Molecular and Cellular Cardiology, 49 412-426 (2010) [C1] Nova
2010 Imtiaz Mohammad S, Von Der Weid Pierre-Yves, Van Helden Dirk Ferdinand, 'Synchronization of Ca2+oscillations: A coupled oscillator-based mechanism in smooth muscle', FEBS Journal, 277 278-285 (2010) [C1] Nova
2010 Sharafutdinova Galiya, Holdsworth John Lionel, Van Helden Dirk Ferdinand, 'Calculated two-photon fluorescence correction factors for reflective scan engines', Applied Optics, 49 1472-1479 (2010) [C1] Nova
2010 Sharafutdinova Galiya, Holdsworth John Lionel, Van Helden Dirk Ferdinand, 'Improved field scanner incorporating parabolic optics. Part 2: experimental verification and potential for volume scanning', Applied Optics, 49 5517-5527 (2010) [C1] Nova
2010 Van Helden Dirk Ferdinand, Laver Derek Rowland, Holdsworth John Lionel, Imtiaz Mohammad S, 'Generation and propagation of gastric slow waves', Clinical and Experimental Pharmacology and Physiology, 37 516-524 (2010) [C1] Nova
2009 Sharafutdinova Galiya, Holdsworth John Lionel, Van Helden Dirk Ferdinand, 'Improved field scanner incorporating parabolic optics: Part 1: Simulation', Applied Optics, 48 4389-4396 (2009) [C1] Nova
2008 Odell Adam Francis, Van Helden Dirk Ferdinand, Scott Judith Louise, 'The spectrin cytoskeleton influences the surface expression and activation of human transient receptor potential channel 4 channels', Journal of Biological Chemistry, 283 4395-4407 (2008) [C1] Nova
2008 Von Der Weid Pierre-Yves, Rahman Mozibur, Imtiaz Mohammad Sahariq, Van Helden Dirk Ferdinand, 'Spontaneous transient depolarizations in lymphatic vessels of the guinea pig mesentery: Pharmacology and implication for spontaneous contractility', American Journal of Physiology: Heart and Circulatory Physiology, 295 H1989-H2000 (2008) [C1] Nova
2007 Imtiaz Mohammad Sahariq, Zhao Jun, Hosaka Kayoko, Von Der Weid P Y, Crowe M, Van Helden Dirk Ferdinand, 'Pacemaking through Ca2+ stores interacting as coupled oscillators via membrane depolarization', Biophysical Journal, 92 3843-3861 (2007) [C1]
2007 Smith Roger, Van Helden Dirk Ferdinand, Hirst Jonathan James, Zakar Tamas, Read Mark A, Chan Eng Cheng, Palliser Hannah Kate, Grammatopoulos D, Nicholson Richard Charles, Parkington H C, 'Pathological interactions with the timing of birth and uterine activation', Australian & New Zealand Journal of Obstetrics & Gynaecology, 47 430-437 (2007) [C1]
2006 Dielenberg Robert, Halasz P, Hosaka Kayoko, Van Helden Dirk Ferdinand, 'Vessel motion measurement in real-time using movement detection at multiple regions of interest', Journal of Neuroscience Methods, 152 40-47 (2006) [C1]
2006 Hosaka Kayoko, Rayner Sharyn E, Von Der Weid P Y, Zhao Jun, Imtiaz Mohammad Sahariq, Van Helden Dirk Ferdinand, 'Calcitonin gene-related peptide activates different signaling pathways in mesenteric lymphatics of guinea pigs', American Journal of Physiology-Heart and Circulatory Physiology, 290 H813-H822 (2006) [C1]
2006 Imtiaz Mohammad Sahariq, Katnik C P, Smith D W, Van Helden Dirk Ferdinand, 'Role of voltage-dependent modulation of store Ca2+ release in synchronization of Ca2+ oscillations', Biophysical Journal, 90 1-23 (2006) [C1] Nova
2006 Van Helden Dirk Ferdinand, Hosaka Kayoko, Imtiaz Mohammad Sahariq, 'Rhythmicity in the microcirculation', Clinical Hemorheology and Microcirculation, 34 59-66 (2006) [C1]
2005 Odell Adam Francis, Scott Judith Louise, Van Helden Dirk Ferdinand, 'Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4', Journal of Biological Chemistry, 280 37974-37987 (2005) [C1] Nova
2004 Ferrusi I, Zhao Jun, Van Helden Dirk Ferdinand, Von Der Weid Pierre-Yves, 'Cyclopiazonic acid decreases spontaneous transient depolarizations in guinea pig mesenteric lymphatic vessels in endothelium-dependent and -independent manners', Am J Physiol Heart Circ Physiol, 286 H2287-H2295 (2004) [C1]
2003 Van Helden Dirk Ferdinand, Imtiaz Mohammad Sahariq, 'Ca2+ phase waves: a basis for cellular pacemaking and long-range synchronicity in the guinea-pig gastric pylorus', The Journal of Physiology, 548.1 271-296 (2003) [C1] Nova
2003 Zhao Jun, Van Helden Dirk Ferdinand, 'ET-1-associated vasomotion and vasospasm in lymphatic vessels of the guinea-pig mesentery', British Journal of Pharmacology, 140 1399-1413 (2003) [C1]
2002 Imtiaz Mohammad Sahariq, Smith Dw, Van Helden Dirk Ferdinand, 'A Theoretical Model of Slow Wave Regulation Using Voltage-Dependent Synthesis of Inositol 1,4,5-Trisphosphate', Biophysical Journal, 83 1877-1890 (2002) [C1] Nova
2002 Zhao Jun, Van Helden Dirk Ferdinand, 'ATP-induced endothelium-independent enhancement of lymphatic vasomotion in guinea-pig mesentery involves P2x and P2y receptors', British Journal of Pharmacology, 137 477-487 (2002) [C1] Nova
2001 Von Der Weid P-Y, Zhao Jun, Van Helden Dirk Ferdinand, 'Nitric oxide decreases pacemaker activity in lymphatic vessels of guinea pig mesentery', Am J Physiol Heart Circ Physiol, 280 H2707-H2716 (2001) [C1]
2000 Van Helden Dirk Ferdinand, Imtiaz Mohammad Sahariq, Nurgaliyeva K, Von Der Weid P-Y, Dosen Peter John, 'Role of calcium stores and membrane voltage in the generation of slow wave action potentials in guinea-pig gastric pylorus', Journal of Physiology, 524.1 245-265 (2000) [C1]
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Conference Publication (37 outputs)

Full Written Paper - Refereed (E1) (3 outputs)

Year Citation Link
2011 Holdsworth John Lionel, Sharafutdinova Galiya, Sanderson Michael J, Van Helden Dirk Ferdinand, 'Off-axis parabolic optical relays: almost perfect imaging', Proceedings of SPIE: 22nd Congress of the International Commission for Optics: Light for the Development of the World, Puebla, Mexico (2011) [E1]
2010 Sharafutdinova Galiya, Holdsworth John Lionel, Van Helden Dirk Ferdinand, 'Comparative scan engine field flatness', 19th Australian Institute of Physics Congress. Extended Abstracts and Refereed Full Papers, Melbourne, Vic (2010) [E1] Nova
2009 Sharafutdinova Galiya, Holdsworth John Lionel, Legge Samuel Robert, Van Helden Dirk Ferdinand, 'Comparative performance of four-mirror parabolic and spherical afocal relays', ACOLS ACOFT 09 Conference: Proceedings of the Australasian Conference on Optics, Lasers and Spectroscopy and Australian Conference on Optical Fibre Technology in Association, Adelaide, SA (2009) [E1] Nova

Full Written Paper - Non Refereed (E2) (5 outputs)

Year Citation Link
2009 Sharafutdinova Galiya, Holdsworth John Lionel, Van Helden Dirk Ferdinand, 'Scan engine induced pulse broadening in two-photon microscopy', Nanophotonics Down Under 2009: Devices and Applications: Program, Melbourne, VIC (2009) [E2] Nova
1999 Imtiaz Mohammad Sahariq, Van Helden Dirk Ferdinand, 'A Mathematical Model of Depolarization-induced Slow Wave Action Potentials Arising by Intracellular Ca2+ Release from Inositol 1,4,5-Trisphosphate Sensitive Ca2+ Stores', Proceedings of the Australian Physiological and Pharmacological Society, Newcastle, Australia (1999) [E2]
1999 Van Helden Dirk Ferdinand, Imtiaz Mohammad Sahariq, Nurgaliyeva K, Von Der Weid P-Y, Dosen Peter John, 'Evidence that Slow Waves in the Guinea-Pig Gastric Pylorus are Mediated by Inositol 1,4,5-Trisphosphate-Sensitive Ca2+ Release', Proceedings of the Australian Physiological and Pharmacological Society, Newcastle, Australia (1999) [E2]
1999 Van Helden Dirk Ferdinand, Zhao Jun, 'Lymphatic Vasomotion', Proceedings of the Australian Physiological and Pharmacological Society, Newcastle, Australia (1999) [E2]
1999 Zhao Jun, Gao J, Van Helden Dirk Ferdinand, 'The Effect of Neuropeptide Y on Vasomotion of Guinea-Pig Mesenteric Lymphatics', Proceedings of the Australian Physiological and Pharmacological Society, Newcastle, Australia (1999) [E2]
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Extract of Paper (E3) (29 outputs)

Year Citation Link
2012 Li Jingjing, Imtiaz Mohammad Sahariq, Beard N A, Dulhunty A F, Thorne Rick Francis, Van Helden Dirk Ferdinand, Laver Derek Rowland, 'Adrenergic stimulation alters RyR2 regulation by Ca2+ and Mg2+', Heart, Lung and Circulation: Abstracts of ISHR Auckland Workshop, Auckland, NZ (2012) [E3]
2011 Mehra Divya Rajendra, Van Helden Dirk Ferdinand, Hwang H S, Knollmann B, Laver Derek Rowland, 'Role of cardiac Na+ channel blockers in inhibiting the cardiac calcium release channel', Proceedings of the Australian Physiological Society 2011, Perth (2011) [E3]
2011 Walweel K, Li Jingjing, Van Helden Dirk Ferdinand, Imtiaz Mohammad Sahariq, Molenaar P, Laver Derek Rowland, 'Regulation of RyRs by intracellular Ca2+ and Mg2+ compared in sheep, rat and human heart', Proceedings of the Australian Physiological Society 2011, Perth (2011) [E3]
2010 Gravina Fernanda Sbaraini, Van Helden Dirk Ferdinand, De Oliveira Ramatis, Kerr Karen Patricia, Jobling Phillip, 'Relaxant effects of methanandamide unmasked by indomethacin in the mouse uterus', Australasian Society of Clinical and Experimental Pharmacology and Toxicology (ASCEPT) Annual Scientific Meeting, Melbourne, 2010, Melbourne, Vic (2010) [E3]
2010 Zhang Huiming, Van Helden Dirk Ferdinand, Offler Christina Eleanor, McCurdy David William, Patrick John William, 'A two-pore calcium channel is a component of the signalling cascade leading to wall ingrowth formation in transfer cells', Plant Membrane Biology 15th International Workshop, Adelaide 2010: Programme & Abstracts, Adelaide, S.A. (2010) [E3]
2010 Zhang Huiming, Van Helden Dirk Ferdinand, Offler Christina Eleanor, McCurdy David William, Patrick John William, 'Calcium is a component of the signalling cascade leading to wall ingrowth formation in transfer cells', International Conference on Plant Vascular Biology 2010: PVB2010, Columbus, OH (2010) [E3]
2010 Zhang Huiming, Van Helden Dirk Ferdinand, Offler Christina Eleanor, McCurdy David William, Patrick John William, 'Signalling related to solute and hormone transport I', Plant Membrane Biology 15th International Workshop, Adelaide 2010: Programme & Abstracts, Adelaide, S.A. (2010) [E3]
2009 De Oliveira Ramatis, Howlett Marcus Christian, Gravina Fernanda Sbaraini, Imtiaz Mohammad Sahariq, Callister Robert John, Brichta Alan Martin, Van Helden Dirk Ferdinand, 'Effect of antioxidants in pacemaking of mice locus coeruleus neurons', ANS 2009 Abstracts: Posters, Canberra, ACT (2009) [E3]
2009 De Oliveira Ramatis, Howlett Marcus Christian, Gravina Fernanda Sbaraini, Imtiaz Mohammad Sahariq, Callister Robert John, Brichta Alan Martin, Van Helden Dirk Ferdinand, 'Ion channel modulation by reactive species in mice locus coeruleus neurons', Journal of Physiological Sciences, Kyoto, Japan (2009) [E3]
2009 Gravina Fernanda Sbaraini, Jobling Phillip, Kerr Karen Patricia, De Oliveira Ramatis, Van Helden Dirk Ferdinand, 'Identification of cannabinoid receptor 1 and the effect of methanandamide on uterine contractions of the mouse uterus', 1st National Symposium on Advances in Urogenital and Gut Research, Melbourne, VIC (2009) [E3]
2009 Gravina Fernanda Sbaraini, Kerr Karen Patricia, Sandow Shaun, De Oliveira Ramatis, Parkington Helena, Imtiaz Mohammad Sahariq, Van Helden Dirk Ferdinand, 'Intracellular calcium stores in mouse uterus: SR and Mitochondria', Journal of Physiological Sciences, Kyoto, Japan (2009) [E3]
2009 Hollins Sharon Lee, Johnstone Daniel McKenzie, Graham Ross, Van Helden Dirk Ferdinand, Kerr Karen Patricia, Laver Derek Rowland, Metelerkamp Kirsty Meredith, Trinder Deborah, Fleming Robert, Scott Rodney, Olynyk John, Milward Adrienne Elizabeth, 'Cardiac gene expression in mouse models of iron loading disorders', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
2009 Hollins Sharon Lee, Johnstone Daniel McKenzie, Van Helden Dirk Ferdinand, Kerr Karen Patricia, Laver Derek Rowland, Metelerkamp Kirsty Meredith, Scott Rodney, Milward Adrienne Elizabeth, 'Cardiac gene expression in mouse models of iron loading', ASMR XVII NSW Scientific Meeting: Programme and Abstracts, Sydney, NSW (2009) [E3]
2009 Kerr Karen Patricia, Jobling Phillip, Gravina Fernanda Sbaraini, Van Helden Dirk Ferdinand, 'Contractility of the lower uterus and upper vagina in the mouse', 43rd ASCEPT Annual Scientific Meeting: Proceedings, Sydney, NSW (2009) [E3]
2009 Laver Derek Rowland, Quail Anthony Walker, Sitsapesan Holly, Van Helden Dirk Ferdinand, 'The effect of volatile anaesthetics on the cardiac ryanodine receptor', Biophysical Journal, Boston, MA (2009) [E3]
2009 Mehra Divya Rajendra, Van Helden Dirk Ferdinand, Knollmann Bjorn, Laver Derek Rowland, 'Flecainide inhibits CPVT induced cardiac arrhythmias by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass', 33rd Annual Meeting of the Australian Society for Biophysics: Program, Ballarat, VIC (2009) [E3]
2009 Sharafutdinova Galiya, Holdsworth John Lionel, Van Helden Dirk Ferdinand, 'A new scanner design for two-photon fluorescence fast imaging microscopy', Light in Life Sciences Conference 2009: Program, Melbourne, VIC (2009) [E3]
2009 Van Helden Dirk Ferdinand, Imtiaz M S, Von Der Weid P Y, ''Lymphatic hearts' - Are they really that primitive?', Journal of Vascular Research, Queenstown, NZ (2009) [E3]
2009 Zhang Huiming, Van Helden Dirk Ferdinand, McCurdy David William, Offler Christina Eleanor, Patrick John William, 'Calcium functions in the signalling cascade leading to wall ingrowth formation in transfer cells', ComBio 2009, Christchurch, NZ (2009) [E3]
2008 De Oliveira Ramatis, Howlett Marcus Christian, Gravina Fernanda Sbaraini, Imtiaz Mohammad Sahariq, Callister Robert John, Brichta Alan Martin, Van Helden Dirk Ferdinand, 'Influence of mitochondria in the interspike interval pacemaking currents of mice Locus Coeruleus neurons', Proceedings of the Australian Physiological Society, Melbourne, VIC (2008) [E3]
2008 Gravina Fernanda Sbaraini, Kerr Karen Patricia, De Oliveira Ramatis, Parkington H, Imtiaz Mohammad Sahariq, Van Helden Dirk Ferdinand, 'Effects of the mitochondrial inhibitors CCCP, rotenone and CGP37157 on spontaneous contractions in the mouse uterus', Proceedings of the Australian Health and Medical Research Congress 2008, Brisbane, QLD (2008) [E3]
2008 Gravina Fernanda Sbaraini, Kerr Karen Patricia, Sandow S, De Oliveira Ramatis, Parkington H C, Imtiaz Mohammad Sahariq, Van Helden Dirk Ferdinand, 'Uterine spontaneous contractions in the estrous cycle and the effect of mitochondrial inhibitors', Proceedings of the Australian Physiological Society, Melbourne, VIC (2008) [E3]
2008 Imtiaz Mohammad Sahariq, Van Helden Dirk Ferdinand, 'Pacemaking in lymphatic smooth muscle', Journal of Vascular Research, Hamilton Island, QLD (2008) [E3]
2008 Laver Derek Rowland, Quail Anthony Walker, Sitsapesan H, Van Helden Dirk Ferdinand, 'Effect of volatile anaesthetics on the calcium release channel in the heart', Proceedings of the Australian Physiological Society, Melbourne, VIC (2008) [E3]
2008 Van Helden Dirk Ferdinand, Laver Derek Rowland, Imtiaz Mohammad Sahariq, 'Ca2+ phase waves: A fundamental mechanism underlying propagation of gastric slow waves', Proceedings of the Australian Physiological Society, Melbourne, VIC (2008) [E3]
2006 Hosaka Kayoko, Rayner Sharyn E, Von Der Weid P Y, Zhao J, Imtiaz Mohammad Sahariq, Van Helden Dirk Ferdinand, 'Calcitonin gene-related peptide activates different signalling pathways in mesenteric lymphatics of the guinea pig', Proceedings of the Australian Neuroscience Society, Sydney (2006) [E3]
2005 Honen Bonny Nicole, Dalton Rebecca Louise, Van Helden Dirk Ferdinand, Laver Derek Rowland, 'Acute application of n-3 polyunsaturated fatty acids modify calcium sparks in permeabilised rat cardiac myocytes', Proceedings of the Australian Physiological Society, Canberra (2005) [E3]
2004 Honen Bonny Nicole, Saint David A, Van Helden Dirk Ferdinand, Laver Derek Rowland, 'The effects of fatty acids on SR calcium release channels from cardiac muscle', Biophysical Journal, Maryland, USA (2004) [E3]
2004 Krajniak Stephanie Gai, Callister Robert John, Imtiaz Mohammad Sahariq, Brichta Alan Martin, Van Helden Dirk Ferdinand, 'Investigation of a brain rhythm', Proceedings of the Australian Neuroscience Society, Australia (2004) [E3]
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