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Prof. Alistair Sim

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Funding

Summary

Number of grants77
Total funding$8,217,601

For project grants received while at an institution other that the University of Newcastle, details are shown in italics.

Seeking students for this project. - Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2008 (2 grants)

PP2A: a novel target for leukaemia therapy$300,000

PP2A: A new target for asthma therapy$20,000

2007 (6 grants)

Functional Characterisation of a New Regulatory Mechanism for CaMKII at Synapses in Vivo$526,500

Heat Shock Proteins in Myometrium$437,750

FACSAria - Fluorescence activated cell sorter$300,000

HMRI Contribution toward FACSAria - Fluorescence activated cell sorter$52,000

Differential regulation of human mast cell degranulation by discrete forms of protein phosphatase 2A$50,000

Polymerase Chain Reaction (PCR) machine and Spectrophotometer$20,000

2006 (13 grants)

Advanced technology for transcriptomics, genomics and gene mapping$850,000

PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143

PRC - Priority Research Centre for Brain & Mental Health Research (CBMHR)$524,282

PRC Priority Research Centre for Asthma & Respiratory Diseases$524,282

Live cell imaging facility$149,100

Targeting protein phosphatases to control mast cell activation$50,000

A novel approach to the control of mast cell activation$20,000

Functional Characterisation of CaMKII Phosphorylate at a New Site in vivo$20,000

Identification of early-life signals induced in response to infection that predispose to asthma in later life$20,000

Novel protein phosphatase interactions in cancer$10,000

High speed computer for a live cell imaging system$3,000

Human Proteome Organisation World Congress, Long Beach California, 28/10/2006 - 1/11/2006$2,400

BioRad Mini-PROTEAN3 Electrophoresis system$995

2005 (5 grants)

High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation$207,189

Novel Substrates for High Sensitivity MALDI$14,696

2005 RIBG allocation$14,500

Regulation of Insulin Secretion by Protein Phosphatases$10,000

12th International Conference on Second Messengers and Phosphoproteins, 10-14 July 2005$2,500

2004 (6 grants)

Differential regulation of two modes of exocytosis by protein phosphatases$393,750

Biacore3000-Expansion of Proteomics Facility$187,341

Biacore3000-Expansion of Proteomics Facility$70,660

Investigation of a novel molecular target for a new anti-ashtma therapy$16,000

Regulation of the neuronal RNA binding protein, pipping by protein phosphorylation$14,500

12th International Conference on Second Messengers and Phosphoproteins, 3-7 August 2004$2,400

2003 (3 grants)

High Throughput 2-dimensional electrophoresis$36,443

Regulation of neuronal exocytosis by protein phosphatase 2A$15,000

EMBO Europhosphatases 2003 Barceloa, Spain 28 June - 3 July 2003$2,400

2002 (6 grants)

Proteomic and Genomic Analysis Facility.$473,332

Mechanisms of Glutamate Receptor Maturation in Chicken Brain$417,000

Peltier Thermal Cycler and associated equipment essential for establishing cDNA Retroviral Libraries$21,315

The role of Protein Phosphatase 2A in synaptic vesicle transport$13,000

Interaction of Protein Phosphatase 2A with the Neuron-specific RNA binding Protein, PIPPin$10,000

FASEB Summer Research Conference on Protein Phosphatases, USA 13 - 19 July, 2002$2,400

2001 (5 grants)

Reciprocal Regulation of Kinases and Phosphatases in Long Term Synaptic Plasticity$15,000

Control of Catecholamine Synthesis by Tyrosine Hydroxylase.$13,000

Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770

Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770

EMBO Conference on Protein Phosphatases and Phosphorylation, Germany 8-12 July 2001$2,400

2000 (3 grants)

Targeting Protein Phosphatase 2A to Regulate DNA Repair.$20,000

Secretatogue-Induced Translocation of Protein Phosphatase 2A in Mast Cells.$14,500

FASEB Summer Research Conference on Protein Phosphatases, USA 23-29 July 2000$2,400

1999 (5 grants)

Targeting of Neuronal Protein Phosphatase 2A$335,505

Confocal Laser Scanning Microscope Facility.$203,107

FPLC Protein Purification System$16,000

The Role of A-Kinase Anchoring Proteins in Directing the Specificity of Protein Phosphatase 1 Action in Neurons.$11,500

EMBO/FEBS Conference on Protein Phosphorylation and Protein De Panne, Belgium.$2,400

1998 (5 grants)

Molecular Dynamics Storm 860 Tri-mode Analysis System$35,000

Control of the nervous system by protein phosphatases and anchoring prteins$19,000

Identification of protein phosphatases acting on Tyrosine Hydroxylase in bovine adrenal chromaffin cells.$19,000

The Role of Protein Phosphatases in Allergic Response Mast Cell Secretion$16,486

Characterisation of Neuronal Protein Phosphatase 1 Binding Proteins.$11,500

1997 (5 grants)

Role of Protein Phosphorylation in the Control of Glutamate Release from Nerve Terminals.$178,409

Characteristation of Novel Molecular Probes for Protein Phosphatases.$160,000

Modulation of Neurotransmitted Release by Carboxyl-methylation and tyrosine Phosphorylation of Protein Phosphatase type 2A.$18,000

Molecular Characterisation of Protein Phosphatase 2A.$8,500

Joint Meeting of the International and American Societies for Neurochemistry, Boston, USA, 20-26 July 1997$2,500

1996 (3 grants)

Molecular characterisation of cytoskeletal protein phosphatase 2A$60,662

Purchase Shaking Incubator and Peltier Thermocycler$10,000

Federation of American Societies for Experimental Biology, Colorado, USA, 21-26 July 1996$2,400

1995 (4 grants)

Regulation of neuronal protein phosphatases types 1 & 2A.$218,471

95APP. High resolution purification of intra-cellular signalling proteins from brain by FPLC.$20,000

Phosphorylation of glycoprotein GP-180:- Implications for NMDA-type glutamate receptor function$9,000

Intern. Society for Neurochemistry, Japan, 2-7 July$2,400

1994 (2 grants)

The control of tyrosine hydroxylase activity by protein phosphorylation.$6,000

Do sigma binding site ligands modulate neurotransmission by molecular mechanisms involving protein phosphorylation in neuronal tissue$5,000

1993 (2 grants)

Advance Warning Of Cyanobacterial Activity$119,637

'ISN Bien. Meet',Montpellier-22 - 27 Aug.93,'European Protein Phosphatase Meeting'Bressanone,19-23 Sept 1993,'1st Int. Symp.on Cyanobacteria,Bath,27-29Sept$2,400

1992 (2 grants)

92,93,94GRANT. The Regulation Of Protein Phosphatases In The Brain$183,006

Characterisation Of Novel Inhibitions And Activators Of Protein Phosphatases And Protein Kinases Isolated From Australian Marine Invertebrates.$25,000