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Prof. Adam McCluskey

Work Phone (02) 4921 6486
Fax (02) 4921 5472
Email
Office C318, Chemistry

Highlighted Publications

Year Citation Link
2003 McCluskey Adam, Keller P A, Morgan J, Garner James Andrew, 'Synthesis, molecular modeling and biological activity of methyl and thiomethyl substituted pyrimidines as corticotropin releasing hormone type 1 antagonists', Organic and Biomolecular Chemistry, 1 3353-3361 (2003) [C1] Nova
2011 Von Kleist Lisa, Stahlschmidt Wiebke, Bulut Haydar, Gromova Kira, Puchkov Dmytro, Robertson Mark James, Macgregor Kylie Anne, Tomlin Nikolay, Pechstein Arndt, Chau Ngoc, Chircop Megan, Sakoff Jennette Anne, Von Kries Jens Peter, Saenger Wolfram, Krausslich Hans-Georg, Shupliakov Oleg, Robinson Phillip J, McCluskey Adam, Haucke Volker, 'Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition', Cell, 146 471-484 (2011) [C1]
2010 Odell Luke, Howan Dian, Gordon Christopher Peter, Robertson Mark James, Chau Ngoc, Mariana Anna, Whiting Ainslie E, Abagyan Ruben, Daniel James A, Gorgani Nick N, Robinson Phillip J, McCluskey Adam, 'The Pthaladyns: GTP competitive inhibitors of Dynamin I and II GTPase derived from virtual screening', Journal of Medicinal Chemistry, 53 5267-5280 (2010) [C1] Nova
2011 Gordon Christopher Peter, Young Kelly Ann, Hizartzidis Lacey, Deane Fiona Maria, McCluskey Adam, 'Investigation of the one-pot synthesis of quinolin-2-(1H)-ones and the discovery of a variation of the three-component Ugi reaction', Organic and Biomolecular Chemistry, 9 1419-1428 (2011) [C1]

Publications

For items published while at an institution other that the University of Newcastle, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapters In A Book (2 outputs)

Chapter in A1 Book (B1) (2 outputs)

Year Citation Link
2011 Booker Katherine Marie, Holdsworth Clovia Isabel, Bowyer Michael Christian, McCluskey Adam, 'Ionic liquids as porogens in the synthesis of molecularly imprinted polymers', Applications of Ionic Liquids in Science and Technology, Intech, Croatia, 197-212 (2011) [B1]
2002 McCluskey Adam, Lawrance Geoffrey Alan, Leitch Sarah Kathleen, Owen Michael Paul, Hamilton Ian Campton, 'Ionic liquids and metal ions: from green chemistry to ore refining', Ionic Liquids: Industrial applications to green chemistry, American Chemical Society, Washington DC, USA, 199-214 (2002) [B1] Nova

Journal Articles (110 outputs)

Refereed Article in a Scholarly Journal (C1) (109 outputs)

Year Citation Link
2012 Daniel James A, Malladi Chandra S, Kettle Emma, McCluskey Adam, Robinson Phillip J, 'Analysis of synaptic vesicle endocytosis in synaptosomes by high-content screening', Nature Protocols, 7 1649-1655 (2012) [C1]
2012 Nguyen Tam H, Maucort Guillaume, Sullivan Robert K P, Schenning Mitja, Lavidis Nickolas A, McCluskey Adam, Robinson Phillip J, Meunier Frederic A, 'Actin- and dynamin-dependent maturation of bulk endocytosis restores neurotransmission following synaptic depletion', PLoS One, 7 e36913 (2012) [C1]
2012 Reid Andrew Timothy, Lord Tessa, Stanger Simone Jacqueline, Roman Shaun Daryl, McCluskey Adam, Robinson Phillip J, Aitken Robert John, Nixon Brett, 'Dynamin regulates specific membrane fusion events necessary for acrosomal exocytosis in mouse spermatozoa', Journal of Biological Chemistry, 287 37659-37672 (2012) [C1]
2012 Robertson Mark James, Hadzic Gordana, Ambrus Joseph Imre, Pome Diego Yuri, Hyde Emily Dawn Elizabeth, Whiting Ainslie, Mariana Anna, Von Keist Lisa, Chau Ngoc, Haucke Volker, Robinson Phillip J, McCluskey Adam, 'The Rhodadyns, a new class of small molecule inhibitors of Dynamin GTPase Activity', ACS Medicinal Chemistry Letters, 3 352-356 (2012) [C1]
2012 Robinson Kelly Maree, McCluskey Adam, Attalla Moetaz I, 'An ATR-FTIR study on the effect of molecular structural variations on the CO2 absorption characteristics of Heterocyclic Amines, Part II', Chemphyschem, 13 2331-2341 (2012) [C1]
2012 Tarleton Mark John, Bernhardt P V, McCluskey Adam, 'Crystal structures of (3R,3aR,4S,7R,7aS)-3-(Allyloxy)hexahydro-4,7-epoxyisobenzofuran-1(3H)-on e and (3S,3aR,4S,7R,7aS)-3-((E)-But-2-en-1-yloxy)hexahydro-4,7-epoxyisobenzofu ran-1(3H)-one: Confirmation of NMR predicted stereocentre geometry', Journal of Chemical Crystallography, 42 639-644 (2012) [C1]
2012 Tarleton Mark John, Gilbert Jayne, Sakoff Jenette A, McCluskey Adam, 'Cytotoxic 2-phenyacrylnitriles, the importance of the cyanide moiety and discovery of potent broad spectrum cytotoxic agents', European Journal of Medicinal Chemistry, 57 65-73 (2012) [C1]
2012 Tarleton Mark John, Gilbert Jayne, Sakoff Jennette A, McCluskey Adam, 'Synthesis and anticancer activity of a series of norcantharidin analogues', European Journal of Medicinal Chemistry, 54 573-581 (2012) [C1]
2012 Turner Nicholas William, Holdsworth Clovia Isabel, McCluskey Adam, Bowyer Michael Christian, 'N-2-propenyl-(5-dimethylamino)-1-naphthalene sulfonamide, a novel fluorescent monomer for the molecularly imprinted polymer-based detection of 2,4-dinitrotoluene in the gas phase', Australian Journal of Chemistry, 65 1405-1412 (2012) [C1]
2011 Campbell Bronwyn E, Hofmann Andreas, McCluskey Adam, Gasser Robin B, 'Serine/threonine phosphatases in socioeconomically important parasitic nematodes - Prospects as novel drug targets?', Biotechnology Advances, 29 28-39 (2011) [C1] Nova
2011 Campbell Bronwyn E, Tarleton Mark John, Gordon Christopher Peter, Sakoff Jennette A, Gilbert Jayne, McCluskey Adam, Gasser Robin B, 'Norcantharidin analogues with nematocidal activity in Haemonchus contortus', Bioorganic and Medicinal Chemistry Letters, 21 3277-3281 (2011) [C1] Nova
2011 Chircop Megan, Perera Swetha, Mariana Anna, Lau Hui, Ma Maggie P C, Gilbert Jayne, Jones Nigel C, Gordon Christopher Peter, Young Kelly Ann, Morokoff Andrew, Sakoff Jennette, O'Brien Terence J, McCluskey Adam, Robinson Phillip J, 'Inhibition of dynamin by dynole 34-2 induces cell death following cytokinesis failure in cancer cells', Molecular Cancer Therapeutics, 10 1553-1562 (2011) [C1]
2011 Gordon Christopher Peter, Young Kelly Ann, Hizartzidis Lacey, Deane Fiona Maria, McCluskey Adam, 'Investigation of the one-pot synthesis of quinolin-2-(1H)-ones and the discovery of a variation of the three-component Ugi reaction', Organic and Biomolecular Chemistry, 9 1419-1428 (2011) [C1]
2011 Gordon Christopher Peter, Young Kelly Ann, Robertson Mark James, Hill Timothy Adrian, McCluskey Adam, 'An Ugi-intramolecular Diels-Alder route to highly substituted tetrahydroepoxyisoindole carboxamides', Tetrahedron, 67 554-561 (2011) [C1] Nova
2011 Harper Callista B, Martin Sally, Nguyen Tam H, Daniels Sharl J, Lavidis Nickolas A, Popoff Michael R, Hadzic Gordana, Mariana Anna, Chau Ngoc, McCluskey Adam, Robinson Phillip J, Meunier Frederic A, 'Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulism', Journal of Biological Chemistry, 286 35966-35976 (2011) [C1]
2011 Macgregor Kylie Anne, McCluskey Adam, 'Ionic liquids accelerate access to N-substituted-1,8-naphthalimides', Tetrahedron Letters, 52 767-769 (2011) [C1]
2011 Robertson Mark James, Gordon Christopher Peter, Gilbert Jayne, McCluskey Adam, Sakoff Jennette A, 'Norcantharimide analogues possessing terminal phosphate esters and their anti-cancer activity', Bioorganic & Medicinal Chemistry, 19 5734-5741 (2011) [C1]
2011 Robinson Kelly Maree, McCluskey Adam, Attalla M, 'The effect molecular structural variations has on the CO2 absorption characteristics of heterocyclic amines', Energy Procedia, 4 224-231 (2011) [C1]
2011 Robinson Kelly Maree, McCluskey Adam, Attalla Moetaz I, 'An FTIR spectroscopic study on the effect of molecular structural variations on the CO2 absorption characteristics of heterocyclic amines', ChemPhysChem, 12 1088-1099 (2011) [C1] Nova
2011 Tarleton Mark John, Gilbert Jayne, Robertson Mark James, McCluskey Adam, Sakoff Jennette A, 'Library synthesis and cytotoxicity of a family of 2-phenylacrylonitriles and discovery of an estrogen dependent breast cancer lead compound', MedChemComm, 2 31-37 (2011) [C1]
2011 Tarleton Mark John, McCluskey Adam, 'A flow chemistry route to 2-phenyl-3-(1H-pyrrol-2-yl)propan-1-amines', Tetrahedron Letters, 52 1583-1586 (2011) [C1]
2011 Tarleton Mark John, Young Kelly Ann, Unicomb Elli, McCluskey Siobahnn N, Robertson Mark James, Gordon Christopher Peter, McCluskey Adam, 'A flow chemistry approach to norcantharidin analogues', Letters in Drug Design and Discovery, 8 568-574 (2011) [C1]
2011 Von Kleist Lisa, Stahlschmidt Wiebke, Bulut Haydar, Gromova Kira, Puchkov Dmytro, Robertson Mark James, Macgregor Kylie Anne, Tomlin Nikolay, Pechstein Arndt, Chau Ngoc, Chircop Megan, Sakoff Jennette Anne, Von Kries Jens Peter, Saenger Wolfram, Krausslich Hans-Georg, Shupliakov Oleg, Robinson Phillip J, McCluskey Adam, Haucke Volker, 'Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition', Cell, 146 471-484 (2011) [C1]
2011 Wright Anthony D, McCluskey Adam, Robertson Mark James, Macgregor Kylie Anne, Gordon Christopher Peter, Guenther Jana, 'Anti-malarial, anti-algal, anti-tubercular, anti-bacterial, anti-photosynthetic, and anti-fouling activity of diterpene and diterpene isonitriles from the tropical marine sponge Cymbastela hooperi', Organic and Biomolecular Chemistry, 9 400-407 (2011) [C1]
2010 Bajsa Joanna, McCluskey Adam, Gordon Christopher Peter, Stewart Scott Gordon, Hill Timothy Adrian, Sahu Rajnish, Duke Stephen O, Tekwani Babu L, 'The antiplasmodial activity of norcantharidin analogs', Bioorganic & Medicinal Chemistry Letters, 20 6688-6695 (2010) [C1] Nova
2010 Chircop Megan, Malladi Chandra S, Lian Audrey T, Page Scott L, Zavortink Michael, Gordon Christopher Peter, McCluskey Adam, Robinson Phillip J, 'Calcineurin activity is required for the completion of cytokinesis', Cellular and Molecular Life Sciences, 67 3725-3737 (2010) [C1] Nova
2010 Gordon Christopher Peter, Byrne Nolene, McCluskey Adam, 'A facile, protic ionic liquid route to N-substituted 5-hydroxy-4-methyl-3-oxoisoindoline-1-carboxamides and N-substituted 3-oxoisoindoline-4-carboxylic acids', Green Chemistry, 12 1000-1006 (2010) [C1] Nova
2010 Hill Timothy Adrian, Mariana Anna, Gordon Christopher Peter, Odell Luke, Robertson Mark James, McGeachie Andrew B, Chau Ngoc, Daniel James A, Gorgani Nick N, Robinson Phillip J, McCluskey Adam, 'Iminochromene inhibitors of Dynamins I and II GTPase activity and Endocytosis', Journal of Medicinal Chemistry, 53 4094-4102 (2010) [C1] Nova
2010 Howes Mark T, Kirkham Matther, Riches James, Cortese Katia, Walser Piers J, Simpson Fiona, Hill Michelle M, Jones Alun, Lundmark Richard, Lindsay Margaret R, Hernandez-Deviez Delia J, Hadzic Gordana, McCluskey Adam, Bashir Rumasia, Liu Libin B, Pilch Paul, McMahon Harvey, Robinson Phillip J, Hancock John F, Mayor Satyajit, Parton Robert G, 'Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells', Journal of Cell Biology, 190 675-691 (2010) [C1] Nova
2010 Joshi Sanket, Perera Swetha, Gilbert Jayne, Smith Charlotte M, Mariana Anna, Gordon Christopher Peter, Sakoff Jennette A, McCluskey Adam, Robinson Phillip J, Braithwaite Antony W, Chircop Megan, 'The Dynamin inhibitors MiTMAB and OcTMAB induce Cytokinesis failure and inhibit cell proliferation in human cancer cells', Molecular Cancer Therapeutics, 9 1995-2006 (2010) [C1] Nova
2010 Odell Luke, Howan Dian, Gordon Christopher Peter, Robertson Mark James, Chau Ngoc, Mariana Anna, Whiting Ainslie E, Abagyan Ruben, Daniel James A, Gorgani Nick N, Robinson Phillip J, McCluskey Adam, 'The Pthaladyns: GTP competitive inhibitors of Dynamin I and II GTPase derived from virtual screening', Journal of Medicinal Chemistry, 53 5267-5280 (2010) [C1] Nova
2010 Thaqi Ali, Scott Janet L, Gilbert Jayne, Sakoff Jennette Anne, McCluskey Adam, 'Synthesis and biological activity of Delta-5,6-norcantharimides: Importance of the 5,6-bridge', European Journal of Medicinal Chemistry, 45 1717-1723 (2010) [C1] Nova
2010 Turner Nicholas William, Holdsworth Clovia Isabel, Donne Scott Wilfred, McCluskey Adam, Bowyer Michael Christian, 'Microwave induced MIP synthesis: comparative analysis of thermal and microwave induced polymerisation of caffeine imprinted polymers', New Journal of Chemistry, 34 686-692 (2010) [C1] Nova
2009 Hill Timothy Adrian, Gordon Christopher Peter, McGeachie Andrew B, Venn-Brown Barbara, Odell Luke, Chau Ngoc, Quan Annie, Mariana Anna, Sakoff Jennette A, Chircop Megan, Robinson Phillip J, McCluskey Adam, 'Inhibition of dynamin mediated endocytosis by the dynoles-synthesis and functional activity of a family of indoles', Journal of Medicinal Chemistry, 52 3762-3773 (2009) [C1] Nova
2009 Holland Ian Paul, McCluskey Adam, Sakoff Jennette Anne, Gilbert Jayne, Chau Ngoc, Robinson Phillip J, Motti Cherie A, Wright Anthony D, Van Altena Ian Andrew, 'Steroids from an Australian Sponge Psammoclema sp', Journal of Natural Products, 72 102-106 (2009) [C1] Nova
2009 Mann Jason Peter, McCluskey Adam, Atkin Rob, 'Activity and thermal stability of lysozyme in alkylammonium formate ionic liquids: Influence of cation modification', Green Chemistry, 11 785-792 (2009) [C1] Nova
2009 Odell Luke, Chau Ngoc, Mariana Anna, Graham Mark E, Robinson Phillip J, McCluskey Adam, 'Azido and diazarinyl analogues of bis-tyrphostin as asymmetrical inhibitors of dynamin GTPase', Chemmedchem, 4 1182-1188 (2009) [C1] Nova
2009 Sauer Benjamin, Gilbert Jayne, Sakoff Jennette Anne, McCluskey Adam, 'Synthesis of 4-substituted-3-hydroxy-5-oxo-10-oxa-4-azatricyclo[5.2.1]dec-3-yl Acetic Acid Ethyl Esters as Norcantharidin Analogues', Letters in Drug Design & Discovery, 6 1-7 (2009) [C1] Nova
2009 Turner Nicholas William, Holmes Natalie Patricia, Brisbane Carrie Emma, McGeachie Andrew B, Bowyer Michael Christian, McCluskey Adam, Holdsworth Clovia Isabel, 'Effect of template on the formation of phase-inversed molecularly imprinted polymer thin films: An assessment', Soft Matter, 5 3663-3671 (2009) [C1] Nova
2009 Whitehead Jacqueline Afra, Zhang Jie, McCluskey Adam, Lawrance Geoffrey Alan, 'Comparative leaching of a sulfidic gold ore in ionic liquid and aqueous acid with thiourea and halides using Fe(III) or HSO5- oxidant', Hydrometallurgy, 98 276-280 (2009) [C1] Nova
2009 Zayas Hazit Alabata, Bowyer Michael Christian, Gordon Christopher Peter, Holdsworth Clovia Isabel, McCluskey Adam, 'Synthesis of biaryl-styrene monomers by microwave-assisted Suzuki coupling', Tetrahedron Letters, 50 5894-5895 (2009) [C1] Nova
2008 Hill Timothy Adrian, Stewart Scott Gordon, Gordon Christopher Peter, Ackland Stephen R, Gilbert Jayne, Sauer Benjamin, Sakoff Jenette A, McCluskey Adam, 'Norcantharidin analogues: Synthesis, anticancer activity and protein phosphatase 1 and 2A inhibition', ChemMedChem, 3 1878-1892 (2008) [C1] Nova
2008 Odell Luke, Skopec Jana, McCluskey Adam, 'Isolation and identification of unique marker compounds from the Tasmanian poppy Papaver somniferum N. Implications for the identification of illicit heroin of Tasmanian origin', Forensic Science International, 175 202-208 (2008) [C1] Nova
2008 Thaqi Ali, McCluskey Adam, Scott Janet L, 'A mild Boc deprotection and the importance of a free carboxylate', Tetrahedron Letters, 49 6962-6964 (2008) [C1] Nova
2008 Zhang Jie, Lawrance Geoffrey Alan, Chau Ngoc, Robinson Phillip J, McCluskey Adam, 'From Spanish fly to room-temperature ionic liquids (RTILs): Synthesis, thermal stability and inhibition of dynamin 1 GTPase by a novel class of RTILs', New Journal of Chemistry, 32 28-36 (2008) [C1] Nova
2007 Booker Katherine Marie, Bowyer Michael Christian, Lennard C J, Holdsworth Clovia Isabel, McCluskey Adam, 'Molecularly imprinted polymers and room temperature ionic liquids: Impact of template on polymer morphology', Australian Journal of Chemistry, 60 51-56 (2007) [C1] Nova
2007 Hemley C F, McCluskey Adam, Keller P A, 'Corticotropin releasing hormone - A GPCR drug target', Current Drug Targets, 8 105-115 (2007) [C1]
2007 Hill Timothy Adrian, Stewart Scott Gordon, Ackland Stephen, Gilbert J, Sauer Benjamin, Sakoff Jennette Anne, McCluskey Adam, 'Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation', Bioorganic and Medicinal Chemistry, 15 6126-6134 (2007) [C1] Nova
2007 Hill Timothy Adrian, Stewart Scott Gordon, Sauer Benjamin, Gilbert J, Ackland Stephen, Sakoff J A, McCluskey Adam, 'Heterocyclic substituted cantharidin and norcantharidin analogues-synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activity', Bioorganic and Medicinal Chemistry Letters, 17 3392-3397 (2007) [C1] Nova
2007 McCluskey Adam, Holdsworth Clovia Isabel, Bowyer Michael Christian, 'Molecularly imprinted polymers (MIPs): sensing, an explosive new opportunity?', Organic & Biomolecular Chemistry, 5 3233-3244 (2007) [C1] Nova
2007 Odell Luke, McCluskey Adam, Failes T W, Tiekink E R T, 'Crystal and molecular structures of benzyl-(2-chloro-6-methylpyrimidin-4-yl)amine and benzyl-(4-chloro-6-methylpyrimidin-2-yl)amine: Confirmation of computationally predicted restricted rotation', Journal of Chemical Crystallography, 37 817-824 (2007) [C1]
2007 Qi Ying, Evans I, McCluskey Adam, 'New impurity profiles of recent Australian imported 'ice': Methamphetamine impurity profiling and the identification of (pseudo)ephedrine and Leuckart specific marker compounds', Forensic Science International, 169 173-180 (2007) [C1]
2007 Quan Annie, McGeachie Andrew B, Keating Damien J, Van Dam Ellen M, Rusak Jenny, Chau Ngoc, Malladi Chandra S, Chen Chen, McCluskey Adam, Cousin Michael A, Robinson Phillip J, 'Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II', Molecular Pharmacology, 72 1425-1439 (2007) [C1]
2007 Stewart Scott Gordon, Hill Timothy Adrian, Gilbert Jayne, Ackland Stephen, Sakoff Jennette A, McCluskey Adam, 'Synthesis and biological evaluation of norcantharidin analogues: Towards PP1 selectivity', Bioorganic and Medicinal Chemistry, 15 7301-7310 (2007) [C1] Nova
2007 Whitehead Jacqueline Afra, Zhang Jie, Pereira N, McCluskey Adam, Lawrance Geoffrey Alan, 'Application of 1-alkyl-3-methyl-imidazolium ionic liquids in the oxidative leaching of sulphidic copper, gold and silver ores', Hydrometallurgy, 88 109-120 (2007) [C1]
2006 Booker Katherine Marie, Bowyer Michael Christian, Holdsworth Clovia Isabel, McCluskey Adam, 'Efficient preparation and improved sensitivity of molecularly imprinted polymers using room temperature ionic liquids', Chemical Communications 1730-1732 (2006) [C1] Nova
2006 Griffith Renate, Brown Michael Nicholas, McCluskey Adam, Ashman Leonie Kay, 'Small molecule inhibitors of protein kinases in cancer - How to overcome resistance', Mini-Reviews in Medicinal Chemistry, 6 1101-1110 (2006) [C1] Nova
2006 Keller P A, McCluskey Adam, Morgan J, O'Connor S M J, 'The role of the HPA axis in psychiatric disorders and CRF antagonists as potential treatments', Archiv Der Pharmazie, 339 346-355 (2006) [C1]
2006 Odell Luke, Skopec Jana, McCluskey Adam, 'A `cold synthesis' of heroin and implications in heroin signature analysis: Utility of trifluoroacetic/acetic anhydride in the acetylation of morphine', Forensic Science International, 164 221-229 (2006) [C1]
2006 Qi Ying, Evans Ian D, McCluskey Adam, 'Australian Federal Police seizures of illicit crystalline methamphetamine (`ice') 1998-2002: Impurity analysis', Forensic Science International, 164 201-210 (2006) [C1]
2006 Schwarz Lachlan John, Bowyer Michael Christian, Holdsworth Clovia Isabel, McCluskey Adam, 'Synthesis and evaluation of a molecularly imprinted polymer selective to 2,4,6-trichloroanisole', Australian Journal of Chemistry, 59 129-134 (2006) [C1]
2005 Hill Timothy Adrian, Odell Luke, Edwards Jennifer Kate, Graham M E, McGeachie A B, Rusak J, Quan A, Abagyan R, Scott J L, Robinson P J, McCluskey Adam, 'Small molecule inhibitors of dynamin I GTPase activity: Development of dimeric tyrphostins', Journal of Medicinal Chemistry, 48 7781-7788 (2005) [C1] Nova
2005 Hill Timothy Adrian, Sakoff J A, Robinson P J, McCluskey Adam, 'Parallel solution-phase synthesis of targeted tyrphostin libraries with anticancer activity', Australian Journal of Chemistry, 58 94-103 (2005) [C1] Nova
2005 Holdsworth Clovia Isabel, Bowyer Michael Christian, Lennard C, McCluskey Adam, 'Formulation of cocaine-imprinted polymers utilizing molecular modelling and NMR analysis', Australian Journal of Chemistry, 58 315-320 (2005) [C1] Nova
2005 Leitch Sarah Kathleen, Addison-Jones Jennifer, McCluskey Adam, 'Regioselective N- and C2-electrophilic substitution of 3-substituted indoles (short communication)', Tetrahedron Letters, 46 2915-2918 (2005) [C1] Nova
2005 McCluskey Adam, Leitch Sarah Kathleen, Garner James Andrew, Caden Christine E, Hill Timothy Adrian, Odell Luke, Stewart Scott Gordon, 'BiCl3-mediated opening of epoxides, a facile route to chlorohydrins or amino alcohols: one reagent, two paths', Tetrahedron Letters, 46 8229-8232 (2005) [C1] Nova
2004 Bowyer Michael Christian, Gordon Charles M, Leitch Sarah Kathleen, McCluskey Adam, Ritchie Craig, 'Indium-Mediated Addition of 4-Bromocrotonic Acid to Aldehydes and Ketones - A Simple, High Yielding Route to Alpha-Allyl-Beta-Hydroxy Carboxylic Acids', Australian Journal of Chemistry: an international journal for chemical science, 57 135-137 (2004) [C1]
2004 Garner James Andrew, Hill Timothy Adrian, Odell Luke, Keller Paul, Morgan Jody, McCluskey Adam, 'Identification of Aminopyrimidine Regioisomers via Line Broadening Effects in 1H and 13C NMR Spectroscopy', Australian Journal of Chemistry, 57 1079-1083 (2004) [C1] Nova
2004 Garner James Andrew, Keller Paul A, McCluskey Adam, 'Corticotrophin Releasing Hormone: Chemistry and Recent Developments', Australian Journal of Chemistry, 57 393-407 (2004) [C1]
2004 Hart Matthew E, Chamberlin A Richard, Walkom Cecilia Clare, Sakoff Jeanette A, McCluskey Adam, 'Modified norcantharidins: synthesis, protein phosphatases 1 and 2A inhibition, and anticancer activity', Bioorganic & Medicinal Chemistry Letters, 14 1969-1973 (2004) [C1] Nova
2004 Hill Timothy Adrian, Odell Luke, Quan Annie, Abagyan Ruben, Ferguson Gemma Natasha, Robinson Phillip J, McCluskey Adam, 'Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity', Bioorganic & Medicinal Chemistry Letters, 14 3275-3278 (2004) [C1] Nova
2004 Sakoff Jeannette A, McCluskey Adam, 'Protein Phosphatase Inhibition: Structure Based Design. Towards New Therapeutic Agents', Current Pharmaceutical Design, 10 1139-1159 (2004) [C1]
2004 Sakoff Jennette Anne, Howitt I J, Ackland Stephen, McCluskey Adam, 'Serine/threonine protein phosphatase inhibition enhances the effect of thymidylate synthase inhibition', Cancer Chemotherapy and Pharmacology, 53 225-232 (2004) [C1] Nova
2004 Schwarz Lachlan John, Holdsworth Clovia Isabel, McCluskey Adam, Bowyer Michael Christian, 'Synthesis and Evaluation of a Molecularly Imprinted Polymer Selective to 2,4,6-Trichlorophenol', Australian Journal of Chemistry, 57 759-764 (2004) [C1] Nova
2004 Whitehead Jacqueline Afra, Lawrance Geoffrey Alan, McCluskey Adam, ''Green' leaching: recyclable and selective leaching of gold-bearing ore in an ionic liquid', Green Chemistry, 6 313-315 (2004) [C1] Nova
2004 Whitehead Jacqueline Afra, Lawrance Geoffrey Alan, McCluskey Adam, 'Analysis of Gold in Solutions Containing Ionic Liquids by Inductively Coupled Plasma Atomic Emission Spectometry', Australian Journal of Chemistry, 57 151-155 (2004) [C1] Nova
2003 Correa W, Edwards J, McCluskey Adam, McKinnon I, Scott J L, 'A thermodynamic investigation of solvent-free reactions', Green Chemistry, 5 30-33 (2003) [C1]
2003 Leitch Sarah Kathleen, McCluskey Adam, 'A High Yielding One-Pot Synthesis of Allylic-Vinylic Alcohols: The Adducts of Tetraallylstannane and a,?-Unsaturated Carbonyl Compounds', Synlett, - 699-701 (2003) [C1]
2003 McCluskey Adam, Ackland Stephen, Bowyer Michael Christian, Baldwin Monique Louise, Garner James Andrew, Walkom Cecilia Clare, Sakoff Jennette Anne, 'Cantharidin analogues: synthesis and evaluation of growth inhibition in a panel of selected tumour cell lines', Bioorganic Chemistry, 31 66-77 (2003) [C1] Nova
2003 McCluskey Adam, Keller P A, Morgan J, Garner James Andrew, 'Synthesis, molecular modeling and biological activity of methyl and thiomethyl substituted pyrimidines as corticotropin releasing hormone type 1 antagonists', Organic and Biomolecular Chemistry, 1 3353-3361 (2003) [C1] Nova
2002 Judeh Zma, Ching Cb, Bu J, McCluskey Adam, 'The first Bischler-Napieralski cyclization in a room temperature ionic liquid', Tetrahedron Letters, 43 5089-5091 (2002) [C1] Nova
2002 McCluskey Adam, Ackland Sp, Gardiner E, Walkom Cecilia Clare, Sakoff Ja, 'The inhibition of protein phosphatases 1 and 2A: a new target for rational anti-cancer drug design?', Anti-Cancer Drug Design, 16 291-303 (2002) [C1]
2002 McCluskey Adam, Atherton Mirella Anne, Walkom Cecilia Clare, Bowyer Mc, Sim Atr, Young Dj, Sakoff Ja, 'The first two cantharidin analogues displaying PP1 selectivity', Bioorganic & Medicinal Chemistry Letters, 12 391-393 (2002) [C1] Nova
2002 McCluskey Adam, Robinson Pj, Hill Timothy Adrian, Scott Jl, Edwards Jennifer Kate, 'Green chemistry approaches to the Knoevenagel condensation: comparison of ethanol, water and solvent free (dry grind) approaches', Tetrahedron Letters, 43 3117-3120 (2002) [C1] Nova
2002 McCluskey Adam, Sim Atr, Sakoff Ja, 'Serine-threonine protein phosphatase inhibitors: Development of potential therapeutic strategies', Journal of Medicinal Chemistry, 45 1151-1175 (2002) [C1]
2002 Sakoff Ja, Ackland Sp, Baldwin Monique Louise, Atherton Mirella Anne, McCluskey Adam, 'Anticancer activity and protein phosphatase 1 and 2A inhibition of a new generation of cantharidin analogues', Investigational New Drugs, 20 1-11 (2002) [C1]
2001 Lengyel I, Nairn A C, McCluskey Adam, Toth G, Penke B, Rostas J A P, 'Auto-inhibition of Ca2+/calmodulin-dependent protein kinase II by its ATP-binding domain', Journal of Neurochemistry, 76 1066-1072 (2001) [C1]
2001 McCluskey Adam, Muderawan I W, Muntari, Young D J, 'A highly atom efficient, solvent promoted addition of tetraallylic, tetraallenic and tetrapropargylic stannanes to carbonyl compounds', Journal of Organic chemistry, 66 7811-7817 (2001) [C1]
2001 McCluskey Adam, Walkom Cecilia Clare, Bowyer M C, Ackland S P, Gardiner E, Sakoff Jennette Anne, 'Cantharimides: A new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A', Bioorganic & Medicinal Chemistry Letters, 11 2941-2946 (2001) [C1]
2000 McCluskey Adam, Atherton Mirella Anne, Mudgee Lm, Sim Atr, Sakoff Jennette Anne, Quinn Rj, 'Anhydride modified cantharidin analogues. Is ring opening important in the inhibition of protein phosphatase 2A?', European Journal of Medicinal Chemistry, 35 957-964 (2000) [C1]
2000 McCluskey Adam, Bowyer Mc, Collins E, Sim Atr, Sakoff Jennette Anne, Baldwin Monique Louise, 'Anhydride Modified Cantharidin Analogues: Synthesis, Inhibition of Protein Phosphatase 1 and 2A and Anti-Cancer Activity', Bioorganic and Medicinal Chemistry Letters, 10 1687-1690 (2000) [C1]
2000 McCluskey Adam, Elfick Lynette Glenyce, Morgan J, Garner James Andrew, Keller Pa, 'Corticotropin releasing hormone: Therapeutic implications and medicinal chemistry developments', Bioorganic and Medicinal Chemistry., 8 1213-1223 (2000) [C1]
2000 McCluskey Adam, Finn M, Bowman Maria, Keller P A, Smith Roger, '2,7-dimethylthiazolo[4,5-d] pyradazine-4-(5H)-thione: a corticotrophin releasing hormone type 1 receptor agonist', Australian journal of chemistry 905-8 (2000) [C1]
2000 McCluskey Adam, Finn M, Bowman M, Keller Pa, Smith R, '3,5-Dimethyl-7-hydrazinothiazolo[4,5-d]pyradazine-7-thiol: A corticotrophin releasing hormone type 1 receptor agonist', Australian Journal of Chemistry, 53 905-908 (2000) [C1]
2000 McCluskey Adam, Garner James Andrew, Caballero S, Young Dj, 'Tetraallylstannane and Weinreb amides: a simple 'green' route to N-protected homoallylic alcohols and allyl ketones', Tetrahedron Letters, 41 8147-8151 (2000) [C1]
1999 Garner James Andrew, McCluskey Adam, 'Regiocontrolled amination of dichloropyrimidines in LiC104-Et20 solutions', Heterocyclic Communications, 5, No. 6 503-508 (1999) [C1]
1999 Gordon C M, McCluskey Adam, 'Ionic liquids: a convenient solvent for environmentally friendly allylation reactions with tetraallylstannane', Chemical Communications, -- 1431-1432 (1999) [C1]
1999 Keller P A, Bowman M, Dang K H, Garner James Andrew, Leach S P, Smith R, McCluskey Adam, 'Pharmacophore development for corticotropin-releasing hormone: new insights into inhibitor activity', Journal of Medicinal Chemistry, 42, No. 13 2351-2357 (1999) [C1]
1999 McCluskey Adam, 'The allylation of carbonyl (and acetal) compounds by tetraallylstannane', Green Chemistry, -- 167-168 (1999) [C1]
1999 McCluskey Adam, 'Water organic chemistry: The allylation of carbonyl (and acetal) compounds by tetraallylstannane', Green Chemistry, 1 167 - 168 (1999) [C1]
1999 McCluskey Adam, 'Water promoted organic chemistry. The allylation of carbonyl (and acetal) compounds by tetraallylstannane', Green Chemistry, 1 161-162 (1999) [C1]
1999 McCluskey Adam, Garner James Andrew, 'Garner, J, McCluskey, A, "A simple, expedient synthesis of substituted pyrimidines: Aminolysis of dichloropyrimidines in the presence of LiClO4', Heterocyclic Communications, 5 503 ? 508 (1999) [C1]
1999 McCluskey Adam, Garner James Andrew, Smith R, Leach Sp, Dang Dh, Bowman M, Keller Pa, 'Pharmacophore development for corticotrophin releasing hormone; new insights into inhibitor activity', Journal of Medicinal Chemistry, 42 2351 ? 2357 (1999) [C1]
1999 McCluskey Adam, Gordon Cm, 'Ionic Liquids: c convenient solvent for environmentally friendly allylation reactions with tetraallylstannane', Chemical Communications, 1999 1431 - 1432 (1999) [C1]
1999 McCluskey Adam, Gordon Cm, 'Ionic liquids a convenient solvent for environmentally friendly allylation reactions with tetraallylstannane', Chemical Communications, 1999 1431-1432 (1999) [C1]
1999 McCluskey Adam, Keller Pk, Bowman M, Dang Kh, Garner James Andrew, Leach Sp, Smith R, 'Pharmacophore Development for Corticotrophin-Releasing Hormone: New Insights into Inhibitor Activity', Journal Of Medicinal Chemistry, 42 2351 - 2357 (1999) [C1]
1998 McCluskey Adam, Dunkin Ir, 'Tetrachlorocyclopentadienone O-oxide, A Facile Oxygen Transfer Reagent, Further Evidence for the Disproportionation of Cycloalkoky Radicals', Bulletin of the Chemical Society of Japan, 71 1397-1400 (1998) [C1]
1998 McCluskey Adam, Wayan Muderawan I, Muntari J, Young Dj, 'Solvent Assisted Addition of Tetraallylic, Tetraallenic and Tetraaproparagylic Stannanes to Aldehydes and Acetals', SynLett, -- 909-912 (1998) [C1]
1998 McCluskey Adam, Ying L, Camp D, Moni Rw, Quinn Rj, 'Diimidazo[1,2-C;4',5'-E] Pyrimidines N6-N1 Conformationally Restricted Andenosines', Bioorganic and Medicinal Chemistry Letters, 8 695-698 (1998) [C1]
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Non Refereed Article in a Professional Journal (C3) (1 outputs)

Year Citation Link
2004 McCluskey Adam, Bowyer Michael Christian, 'Synthetic antibodies and the Australian wine industry: A Hunter Valley solution to cork taint?', Australian & New Zealand Grapegrower & Winemaker, 2004 111-115 (2004) [C3]

Review (1 outputs)

A Review of a Single Work (D3) (1 outputs)

Year Citation Link
2003 Keller P A, Kirkwood Kristie Lee, Morgan J, Westcott S, McCluskey Adam, 'The prevention of preterm labour - corticotrophin releasing hormone type 1 receptors as a target for drug design and development', Med. Chem. (2003) [D3]

Conference Publication (18 outputs)

Full Written Paper - Refereed (E1) (1 outputs)

Year Citation Link
2011 Robinson Kelly Maree, McCluskey Adam, Attalla M I, 'The effect of molecular structural variations on the CO2 absorption characteristics of heterocyclic diamines for amine-based post combustion CO2 capture', Chemeca 2011: Engineering a Better World, Sydney (2011) [E1]

Extract of Paper (E3) (17 outputs)

Year Citation Link
2012 Harper C B, Martin S, Nguyen T N, McCluskey Adam, Robinson P J, Meunier F A, 'Role of the presynaptic plasma membrane in sorting local from retrograde vesicular trafficking pathways', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3]
2012 Stehn J R, Haass N K, Bonello T, Desouza M, Kottyan G, Treutlein H, Zeng J, Nascimento P R, Butler T, Allanson M, Fath T, Hill Timothy Adrian, McCluskey Adam, Schevzov G, Palmer S, Hardeman E C, Winlaw D, Reeve V E, Dixon I, Weninger W, Cripe T P, Gunning P, 'Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells', Experimental Dermatology, Marburg, Germany (2012) [E3]
2011 Stehn J R, Haass N K, Desouza M, Sequeira V B, Treutlein H, Zeng J, Nascimento P R B B, Butler T, McCluskey Adam, Palmer S, Hardeman E, Winlaw D, Weninger W, Gunning P, 'Developing chemotherapeutics which disable the actin cytoskeleton of melanoma cells', Pigment Cell & Melanoma Research, Tampa, FL (2011) [E3]
2010 Bonello T, Stehn J, Schevzov G, Coombes J, McCluskey Adam, Haass N, Dixon I, Gunning P, 'Targeting the tropomyosin isoform TM5NM1 impairs tumour survival, proliferation and migration', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Australia (2010) [E3]
2010 Chircop M, Perera S, Ma M P C, Lau H, Gilbert J, Jones N C, Dabacco G, Gordon Christopher Peter, Young K A, Morokoff A, Sakoff Jennette Anne, O'Brien T, McCluskey Adam, Robinson P J, 'Dynole 34-2 is a potent inhibitor of dynamin that induces cell death following cytokinesis failure and suppresses glioblastoma tumour growth in vivo', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Australia (2010) [E3]
2010 Gunning P W, Hook J, Schevzov G, Desouza M, Creed S, McCluskey Adam, Hardemann E C, Dixon I, Stehn J, 'Actin filaments containing tropomyosin Tm5NM1/2 perform essential functions as revealed by gene knockouts and anti-Tm drugs', The American Society for Cell Biology 50th Annual Meeting Abstracts, Phildelphia, PA (2010) [E3]
2010 Joshi Sanket, Gaddipatti Swetha, Gilbert Jayne, Smith Charlotte M, Gordon Christopher Peter, Sakoff Jennette Anne, McCluskey Adam, Robinson Phillip J, Braithwaite Antony W, Chircop Megan, 'Dynamin inhibition: A new therapeutic approach for the treatment of cancer', AACR 101st Annual Meeting 2010. Abstracts, Washington, DC (2010) [E3]
2010 Mariana A, Hill T A, McGeachie A B, Chau N, Daniel J A, Gorgani N N, McCluskey Adam, Robinson P J, 'Towards isoform-selective dynamin inhibitors', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Australia (2010) [E3]
2010 McCluskey Adam, Robinson Phillip J, 'From dyngoes to dynasores: Selective dynamin inhibitors as novel antiepileptic agents', Australasian Society of Clinical and Experimental Pharmacology and Toxicology (ASCEPT) Annual Scientific Meeting, Melbourne, Vic (2010) [E3]
2010 Stehn J, Schevzov G, Bonello T, McCluskey Adam, Haass N, Palmer S, Hardeman E, Allanson M, Reeve V, Gunning P, 'Tropomyosin Tm5NM1: A novel target for cancer therapy', EJC Supplements, Berlin, Germany (2010) [E3]
2009 Robinson P J, McCluskey Adam, 'Dynamin inhibitors reduce synaptic transmission and are novel anti-epileptic drugs', Journal of Neurochemistry, Beijing, China (2009) [E3]
2008 Bajsa J, Sahu R, McCluskey Adam, Duke S O, Tekwani B L, 'Antimalarial activity of cantharidin analogs: potential serine/threonine protein phosphatase inhibitors', Planta Medica, Oxford, MI (2008) [E3]
2008 Wright A, McCluskey Adam, Macgregor K, Guenther J, 'Potential ecological role, chemistry and molecular modelling studies of secondary metabolites isolated from the tropical marine sponge Cymbastela hooperi', Planta Medica, Athens, Greece (2008) [E3]
2007 Chau N, Quan A, Hill Timothy Adrian, McCluskey Adam, Robinson P J, 'The apparent potency of dynamin GTPase inhibitors is dependent on dynamin concentration: a new colorimetric assay (Poster)', 7th IBRO 2007 World Congress of Neuroscience Program, Melbourne (2007) [E3]
2007 McGeachie A B, Odell Luke, Hill Timothy Adrian, Quan A, Chau N, Graham Mark Evan, McCluskey Adam, Robinson Phillip James, 'Analogues of Bis-T-22 potently inhibit endocytosis (Poster)', 7th IBRO 2007 World Congress of Neuroscience Program, Melbourne (2007) [E3]
2007 Quan A, McGeachie A B, Van Dam E M, Chau N, McCluskey Adam, Cousin M A, Robinson Phillip James, 'Mitmab is a surface-active dynamin inhibitor that blocks dynamin i or dynamin ii mediated endocytosis (Poster)', 7th IBRO 2007 World Congress of Neuroscience Program, Melbourne (2007) [E3]
2007 Stehn Justin R, Butler Tanya, Winlaw David, McCluskey Adam, Gunning Peter, 'Tropomyosin containing actin filaments as cancer-specific targets', AACR Meeting Abstracts Online (Abstracts of the 98th AACR Annual Meeting), Los Angeles (2007) [E3]
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Patents (1 outputs)

Patent (I1) (1 outputs)

Year Citation Link
2005 McCluskey Adam, Robinson Phillip James, Hill Timothy Adrian, Methods and agents for inhibiting dynamic-dependent endocytosis (2005) [I1]