Dr Brett Nixon / Staff Profiles / Staff / The University of Newcastle, Australia

About

Introduction

Brett is a lecturer in the Discipline of Biological Sciences within the School of Environmental & Life Sciences.

Qualifications

BSc (Hons)
(University of Newcastle)

PhD
(University of Newcastle / Vertebrate Biocontrol CRC)

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Research

Research Interests

Molecular Basis of Sperm Egg Interaction

Refereed Journal Articles

Nixon Brett, Bielanowicz Amanda Jane, McLaughlin Eileen Anne, Tanphaichitr Nongnuj, Ensslin Michael A, Aitken Robert John, ’Composition and significance of detergent resistant membranes in mouse spermatozoa’, Journal of Cellular Physiology, 218 122-134 (2009) [C1]

De Iuliis Geoffry Nunzio, Thomson Laura K, Mitchell Lisa Ann, Finnie Jane Margaret, Koppers Adam John, Hedges Andrew, Nixon Brett, Aitken Robert John, ’DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress’, Biology of Reproduction, 81 517-524 (2009) [C1]

Dacheux Jean-Louis, Dacheux Francoise, Labas Valerie, Ecroyd Heath, Nixon Brett, Jones Russell Campbell, ’New proteins identified in epididymal fluid from the platypus (Ornithorhynchus anatinus)’, Reproduction Fertility and Development, 21 1002-1007 (2009) [C1]

Ecroyd Heath, Nixon Brett, Dacheux Jean-Louis, Jones Russell Campbell, ’Testicular descent, sperm maturation and capacitation: Lessons from our most distant relatives, the monotremes’, Reproduction Fertility and Development, 21 992-1001 (2009) [C1]

Andrew Megan Narelle, Dunstan Richard Hugh, O'Connor W A, Van Zwieten L, Nixon Brett, Macfarlane Geoffrey Robert, ’Effects of 4-nonylphenol and 17 alpha-ethynylestradiol exposure in the Sydney rock oyster, Saccostrea glomerata: Vitellogenin induction and gonadal development’, Aquatic Toxicology, 88 39-47 (2008) [C1]

Warren W C, Hillier L W, Graves J A M, Birney E, Ponting C P, Grutzner F, Belov K, Miller W, Clarke L, Chinwalla A T, Yang S P, Heger A, Locke D P, Miethke P, Waters P D, Veyrunes F, Fulton L, Fulton B, Graves T, Wallis J, Puente X S, Lopez-Otin C, Ordonez G R, Eichler E E, Chen L, Cheng Z, Deakin J E, Alsop A, Thompson K, Kirby P, Papenfuss A T, Wakefield M J, Olender T, Lancet D, Huttley G A, Smit A F A, Pask A, Temple-Smith P, Batzer M A, Walker J A, Konkel M K, Harris R S, Whittington C M, Wong E S W, Gemmell N J, Buschiazzo E, Jentzsch I M V, Merkel A, Schmitz J, Zemann A, Churakov G, Kriegs J O, Brosius J, Murchison E P, Sachidanandam R, Smith C, Hannon G J, Tsend-Ayush E, McMillan D, Attenborough R, Rens W, Ferguson-Smith M, Lefevre C M, Sharp J A, Nicholas K R, Ray D A, Kube M, Reinhardt R, Pringle T H, Taylor J, Jones Russell Campbell, Nixon Brett, Dacheux J L, Niwa H, Sekita Y, Huang X Q, Stark A, Kheradpour P, Kellis M, Flicek P, Chen Y, Webber C, Hardison R, Nelson J, Hallsworth-Pepin K, Delehaunty K, Markovic C, Minx P, Feng Y C, Kremitzki C, Mitreva M, Glasscock J, Wylie T, Wohldmann P, Thiru P, Nhan M N, Pohl C S, Smith S M, Hou S F, Renfree M B, ’Genome analysis of the platypus reveals unique signatures of evolution’, Nature, 453 175-U1 (2008) [C1]

Walsh Andrew Karl, Whelan Dean, Bielanowicz Amanda Jane, Skinner Brooke Louise, Aitken Robert John, O'Bryan Moira K, Nixon Brett, ’Identification of the molecular chaperone, heat shock protein 1 (chaperonin 10), in the reproductive tract and in capacitating spermatozoa in the male mouse’, Biology of Reproduction, 78 983-993 (2008) [C1]

Bennetts Liga Elizabeth, De Iuliis Geoffry Nunzio, Nixon Brett, Kime M, Nixon Katherine, McVicar C M, Lewis S E, Aitken Robert John, ’Impact of estrogenic compounds on DNA integrity in human spermatozoa: Evidence for cross-linking and redox cycling activities’, Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 641 1-11 (2008) [C1]

Mitchell Lisa Ann, Nixon Brett, Baker Mark Andrew, Aitken Robert John, ’Investigation of the role of SRC in capacitation-associated tyrosine phosphorylation of human spermatozoa’, Molecular Human Reproduction, 14 235-243 (2008) [C1]

Nixon Brett, Jones Russell Campbell, Holland Michael K, ’Molecular and functional characterization of the rabbit epididymal secretory protein 52, REP52’, Biology of Reproduction, 78 910-920 (2008) [C1]

Grutzner F, Nixon Brett, Jones Russell Campbell, ’Reproductive biology in egg-laying mammals’, Sexual Development, 2 115-127 (2008) [C1]

Mitchell Lisa Ann, Nixon Brett, Aitken Robert John, ’Analysis of chaperone proteins associated with human spermatozoa during capacitation’, Molecular Human Reproduction, 13 605-613 (2007) [C1]

Ainsworth Christopher James, Nixon Brett, Jansen R P S, Aitken Robert John, ’First recorded pregnancy and normal birth after ICSI using electrophoretically isolated spermatozoa’, Human Reproduction, 22 197-200 (2007) [C1]

Nixon Brett, Aitken Robert John, McLaughlin Eileen Anne, ’New insights into the molecular mechanisms of sperm-egg interaction’, Cellular and Molecular Life Sciences, 64 1805-1823 (2007) [C1]

Aitken Robert John, Nixon Brett, Lin Minjie, Koppers Adam John, Lee Yun Hwa, Baker Mark Andrew, ’Proteomic changes in mammalian spermatozoa during epididymal maturation’, Asian Journal of Andrology, 9 554-564 (2007) [C1]

Jones Russell Campbell, Dacheux J L, Nixon Brett, Ecroyd H W, ’Role of the epididymis in sperm competition’, Asian Journal of Andrology, 9 493-499 (2007) [C1]

Nixon Brett, Macintyre David Alan, Mitchell Lisa Ann, Gibbs G M, O'Bryan M, Aitken Robert John, ’The identification of mouse sperm-surface-associated proteins and characterization of their ability to act as decapacitation factors’, Biology of Reproduction, 74 275-287 (2006) [C1]

Ainsworth Christopher James, Nixon Brett, Aitken Robert John, ’Development of a novel electrophoretic system for the isolation of human spermatozoa’, Human Reproduction, 20 2261-2270 (2005) [C1]

Nixon Brett, Paul Jonathan Winter, Spiller Cassy M, Attwell-Heap Abigail Georgina, Ashman Leonie Kay, Aitken Robert John, ’Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa’, Journal of Cell Science, 118 4865-4877 (2005) [C1]

Asquith Kelly Lyn, Bielanowicz Amanda Jane, McLaughlin Eileen Anne, Nixon Brett, Aitken Robert John, ’Localization and significance of molecular chaperones, heat shock protein 1, and tumor rejection antigen gp96 in the male reproductive tract and during capacitation and acrosome reaction’, Biology of Reproduction, 72 328-337 (2005) [C1]

Nixon Brett, Asquith Kelly Lyn, Aitken Robert John, ’The role of molecular chaperones in mouse sperm-egg interactions’, Molecular and Cellular Endocrinology, 240 1-10 (2005) [C1]

Asquith Kelly Lyn, Baleato Rosa, McLaughlin Eileen Anne, Nixon Brett, Aitken Robert John, ’Analysis of the mechanisms by which tyrosine phosphorylation regulates spem-zona recognition in the mouse, a chaperone-mediated event?’, Journal of Cell Science, 117 3645-3657 (2004) [C1]

Curry Benjamin John, Su Hua, Law Estelle Grace, McLaughlin Eileen Anne, Nixon Brett, Aitken Robert John, ’Identification of RARhoGAP, a novel putative RhoGAP gene expressed in male germ cells’, Genomics, 84 406-418 (2004) [C1]

Asquith Kelly Lyn, Baleato Rosa, McLaughlin Eileen Anne, Nixon Brett, Aitken Robert John, ’Tyrosine phosphorylation activates surface chaperones facilitating sperm-zona recognition’, Journal of Cell Science, 117 3645-3657 (2004) [C1]

Nixon Brett, Jones Russell Campbell, Hansen Lyall Amanda, Holland Mk, ’Rabbit epididymal secretory proteins. I. Characterization and hormonal regulation’, Biology of Reproduction, 67 133-139 (2002) [C1]

Nixon Brett, Jones Russell Campbell, Clarke Hg, Holland Mk, ’Rabbit epididymal secretory proteins. II. Immunolocalization and sperm association of REP38’, Biology of Reproduction, 67 140-146 (2002) [C1]

Nixon Brett, Hardy Cm, Jones Russell Campbell, Anfrews Jb, Holland Mk, ’Rabbit epididymal secretory proteins. III. Molecular cloning and characterization of the complementary DNA for REP38’, Biology of Reproduction, 67 147-153 (2002) [C1]

Conference Papers