Faculty of Science and Information Technology

Associate Professor Adam McCluskey

• B.Sc.(Hons)
• Ph.D.(Organic Chemistry) [Strathclyde, 1988]
• MRACI
• CChem

• Medicinal Chemistry
  • Inhibition of Protein Phosphatases as a therapeutic Strategy
  • Inhibition of Dynamin GTPase
  • Prevention of Pre-term delivery in Humans: Agonists & antagonists of Corticotrophin Releasing Hormone (CRH)
• Green Chemistry

Overarching Interest is in the application of organic chemistry strategies in the development of new therapeutic agents (Organic and Medicinal Chemistry). Additionally, given environmental and public concerns relating to Chemistry we are driven by a desire to develop Green Chemistry approaches in our organic and medicinal chemistry targets. Emphasis is placed on solvent free reactions, atom efficiency, replacement of volatile organic solvents with environmentally friendly equivalents (ionic liquids), and evaluation of the most efficient synthetic routes to the desired end-points. My group's primary interests are in developing novel compounds with the ability to inhibit a number of signal transduction pathways. The potential outcomes of our research include (but are not limited to) the development of new synthetic methodologies; the development of new drugs & the development of new tools for dissecting signal transduction pathways.

• Organic Chemistry
• Medicinal Chemistry
• Forensic Science

• Katherine Booker - PhD (Chemistry)
  Field test kits for the detection of illicit substances
• Carrie Brisbane - PhD (Chemistry)
  Chemical Listening Devices for the Detection of Illicit Drugs and Explosives
• Michael Brown - PhD (Biological Sciences)
  Inhibitors of KIT Receptor Tyrosine Kinase
• Jennifer Edwards - PhD (Chemistry)
  Green Chemistry Approaches to Knoevenagel Condensation
• Gordana Hadzic - PhD (Chemistry)
  Novel Inhibitors of Dyamine GTPase
• Ian Holland - PhD (Chemistry)
  Bioassy Directed Drug Discovery - Natural Products as New Leads
• Luke Odell - PhD (Chemistry)
  Medicinal Chemistry
• Benjamin Sauer - PhD (Chemistry)
  Chemical Synthesis And Bio-Prospecting: Towards New Antii-Cancer Agents
• Lachlan Schwarz - PhD (Chemistry)
  Investigations Of Selective Detection Methods For Trichlorophenol And Derivatives In Wine
• Ryan Shaw - PhD (Chemistry)
  MIP Sensors - In Field Detection of Illicit Substances
• Kathleen Wright - PhD (Chemistry)
  In Field Sensors for the Detection of Illicit Substances - Application of MIP Technology
• Jie Zhang - PhD (Chemistry)
  Ionic Liquids for Synthesis and Metal Recovery