The University of Newcastle, Researcher report.

Researcher: Dr Peter Wark
School: School of Medicine and Public Health
Commenced with Institution: 16-FEB-1998
Personal URL:

Funded Projects

Please note, only grants administered through the University of Newcastle Research Office are recorded here. For a more complete picture of the researcher's grant history a Personal URL may be supplied, above.

Research Team Initial Year Duration (Years) Funding Body/Client Award Type Title of Project Collaborating Partners Total Cash $ Total Inkind $
Dr Peter Wark;Assoc. Prof Philip Hansbro 1 John Hunter Hospital Charitable Trust Fund Project - Research Grant Miccroarrays to identify novel therapeutic targets for bird flu   14500  
Dr Peter Wark 2008 2 Hunter Medical Research Institute Project - Project Grant Inflammatory mechanisms of airways disease   170000  
Dr Peter Wark 2008 1 Markey Insurance HMRI - HMRI Grant Mechanisms of inflammatory airways disease   40571  
Professor Alistair Sim;Dr Nicole Verrills;Professor John Scott;Dr Peter Wark 2008 1 University of Newcastle Project - Near Miss PP2A: A new target for asthma therapy   20000  
Assoc. Prof Philip Hansbro;Professor Rakesh Kumar;Dr Peter Wark 2008 1 Asthma Foundation of New South Wales Project - Research Grant The use of the components of the bacteria, streptococcus pneumoniae, as novel immunotherapies for asthma   50000  
Dr Peter Wark;Conjoint Pr Peter Gibson;Dr Jodie Simpson;Dr Lisa Wood;Dr Vanessa Murphy;Assoc. Prof Philip Hansbro 2008 1 National Health & Medical Research Council Equipment/Infrastructure - Equipment Grant Becton Dickinson high throughout sampler for the FACSCanto II cytometry system   35000  
Dr Peter Wark;Assoc. Prof Philip Hansbro;Dr Ian Barr 2008 3 National Health & Medical Research Council Project - Project Grant The mechanisms of infection of bronchial epithelial cells by human & avian influenza viruses in chronic airways disease   379650  
Dr Peter Wark;Assoc. Prof Philip Hansbro;Dr Jodie Simpson 2007 2 GlaxoSmithKline Australia Project - Support Grant In vitro response of bronchial epithelial cells and activation of lymphocytes from COPD patients by infection with rhinovirus, respiratory syncytial virus and haemophilus influenza   25000  
Dr Lisa Wood;Dr Peter Wark;Conjoint Pr Peter Gibson;Dr Jodie Simpson;Dr Vanessa Murphy;Professor Paul Foster;Assoc. Prof Philip Hansbro;Assoc. Prof Vicki Clifton;Assoc. Prof Clare Collins;Conjoint Pr Wayne Smith;Professor John Attia 2007 1 National Health & Medical Research Council Equipment/Infrastructure - Equipment Grant Hewlett Packard 7890 series gas chromatograph with accessories   20000  
Dr Peter Wark;Conjoint Pr Peter Gibson;Dr Jodie Simpson;Dr Vanessa Murphy;Dr Lisa Wood;Professor Paul Foster;Assoc. Prof Philip Hansbro 2007 1 National Health & Medical Research Council Equipment/Infrastructure - Equipment Grant Class II biohazard containment hood and carbon dioxide cell culture incubator   20000  
Conjoint Pr Peter Gibson;Assoc. Prof Vicki Clifton;Conjoint Pr Warwick Giles;Professor Michael Hensley;Dr Vanessa Murphy;Dr Peter Wark;Ms Vanessa McDonald;Dr Jodie Simpson;Conjoint A/Prof Bruce Whitehead;Professor Paul Foster;Assoc. Prof Philip Hansbro;Dr Lisa Wood 2007 1 National Health & Medical Research Council Equipment/Infrastructure - Equipment Grant Nitric Oxide Monitoring System (NIOX)   45000  
Dr Peter Wark;Assoc. Prof Philip Hansbro;Dr Jodie Simpson 2007 3 John Hunter Hospital Charitable Trust Fund Project - Research Grant In vitro response of bronchial epithelial cells and activation of lymphocytes to infection with rhinovirus   58848  
Professor Alistair Sim;Dr Nicole Verrills;Professor Paul Foster;Dr Peter Wark;Conjoint Pr Peter Gibson;Mr Gregory Kranias 2007 1 Asthma Foundation of New South Wales Project - Research Grant Differential regulation of human mast cell degranulation by discrete forms of protein phosphatase 2A   50000  
Dr Peter Wark 2007 3 National Health & Medical Research Council Project - Project Grant Chronic Exposure of Bronchial Epithelial Cells to Bacterial Components Modifies their Innate Immune Response to Infection with Respiratory Viruses   313500  
Professor Paul Foster;Conjoint Pr Peter Gibson;Conjoint Pr Kenneth Beagley;Professor Michael Hensley;Assoc. Prof Philip Hansbro;Assoc. Prof Joerg Mattes;Professor Alistair Sim;Dr Peter Wark 2006 3 University of Newcastle Centre - Priority Research Centre PRC Priority Research Centre for Asthma & Respiratory Diseases   206000  
Assoc. Prof Philip Hansbro;Dr Ian Barr;Dr Peter Wark;Dr Paul Selleck;Dr Simone Warner;Professor Paul Foster;Dr Aeron Hurt;Dr Irene Peroulis;Dr John Curran;Conjoint Pr Peter Gibson 2006 1 National Health & Medical Research Council Project - Potential Avian Influenza-Induced Pandemic Surveillance and Analysis of Avian Influenza Viruses in Migratory Birds in Australia   249625  
Dr Peter Wark 2006 1 Hunter Medical Research Institute Project - Project Grant The interaction between airway epithelial cells infected with rhinovirus and lymphocytes from subjects with COPD   15000  
Dr Peter Wark 2006 1 Hunter Medical Research Institute Award - PULSE Early Career Medical Researcher of the Year Award Equipment - Microscope   5000  
Dr Peter Wark 2001 5 National Health & Medical Research Council Fellowship - Neil Hamilton Fairley Fellowship Mechanisms of bronchial epithelial cell activation in rhinovirus infection in asthma, COAD and normal airways   338516  
Conjoint Pr Peter Gibson;Dr Peter Wark 1998 2 Asthma Foundation of New South Wales Project - Research Grant The investigation of airway inflammation and cell death in acute severe asthma   45500  

Research Higher Degree Supervision

For a more complete picture of the researcher's supervision history a Personal URL may be supplied at the top of this page.

Current Student Supervision

Program Supervision Level Research Topic
PhD (Immunology & Microbiol) Co-Supervisor Viral Infections and Exacerbations of Emphysema
PhD (Medicine) Co-Supervisor Mechanisms of Susceptibility to Respiratory Viral Infection in Pregnant Women with Asthma
PhD (Medicine) Principal Supervisor Avian and Human Influenza
PhD (Medicine) Principal Supervisor In vitro response of bronchial epithelial cells and activiation of lymphocytes to infection with rhinovirus
M Philosophy (Medicine) Co-Supervisor An Investigation of obesity, nutritional status, inflammation and co morbidities in COPD
PhD (Medical Biochemistry) Co-Supervisor Resveratrol and airway inflammation associated with Rhinovirus infection in asthma and COPD

Total Equivalent Full-time Student Units (EFTSU):

Supervision Level EFTSU
Masters 0.125
PhD 2.000

Research Publications

Please note, the publications listed here:
(1) relate to the researcher's position at the University of Newcastle only
(2) are for selected categories of publications, and
(3) relate to publication year 1998, onwards.
For a more complete picture of the researcher's publication history a Personal URL may be supplied at the top of this page.

Journal Article

Weckmann M, Collison A, Simpson Jodie Louise, Kopp M V, Wark Peter Alexander, Smyth M J, Yagita H, Matthaei K I, Hansbro Nicole Gower, Whitehead Bruce Foster, Gibson Peter Gerard, Foster Paul Stephen, Mattes Joerg, ’Critical link between TRAIL and CCL20 for the activation of T(H)2 cells and the expression of allergic airway disease’, Nature Medicine, 13 1308-1315 (2007) [C1]

Wark Peter Alexander, Bucchieri F, Johnston S L, Gibson Peter Gerard, Hamilton L, Mimica J, Zummo G, Holgate S T, Attia John Richard, Thakkinstian Ammarin, Davies D E, ’IFN-gamma-induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations’, Journal of Allergy and Clinical Immunology, 120 586-593 (2007) [C1]

Wark Peter Alexander, Gibson Peter Gerard, ’Asthma exacerbations ? 3: Pathogenesis’, Thorax, 61 909-915 (2006) [C1]

Contoli Marco, Message Simon D, Laza-Stanca Vasile, Edwards Michael R, Wark Peter Alexander, Bartlett Nathan, Kebadze Tatiana, Mallia Patrick, Stanciu Luminita A, Parker Hayley L, Slater Louise, Lewis-Antes Anita, Kon Onn M, Holgate Stephen T, Davies Donna E, Kotenko Sergei V, Papi Alberto, Johnston Sebastian L, ’Role of eficient type III interferon-lambda production in asthma exacerbations’, Nature Medicine, 12 1023-1026 (2006) [C1]

Wark Peter Alexander, ’Safety concerns with salmeterol (Editorial)’, Australian Prescriber, 29 118-119 (2006) [C3]

Wark Peter Alexander, ’Safety concerns with salmeterool’, Australian Prescriber, 29 118-119 (2006) [C3]

Wark Peter Alexander, Johnston Sebastian, Bucchieri Fabio, Powell Robert, Puddicombe Sarah, Laza-Stanca Vasile, Holgate Stephen T, Davies Donna E, ’Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus’, Journal of Experimental Medicine, 201 937-947 (2005) [C1]

Wood Lisa Gai, Garg Manohar Lal, Simpson Jodie Louise, Mori Trevor A, Croft Kevin D, Wark Peter Alexander, Gibson Peter Gerard, ’Induced sputum 8-isoprostane concentrations in inflammatory airway diseases’, American Journal of Respiratory and Critical Care Medicine, 171 426-430 (2005) [C1]

Wark Peter Alexander, ’Bronchitis (acute)’, Clinical Evidence, 12 - (2004) [C3]

Wark Peter Alexander, ’Pathogenesis of allergic bronchopulmonary aspergillosis and an evidence-based review of azoles in treatment’, Respiratory Medicine, 98 915-923 (2004) [C1]

Wark Peter Alexander, Hensley Michael John, Saltos Nicholas, Boyle Michael J, Toneguzzi R, Simpson Jodie Louise, McElduff Patrick, Gibson Peter Gerard, ’Anti-inflammatory effect of itraconazole in stable allergic bronchopulmonary aspergillosis: A randomized controlled trial’, The Journal of Allergy and Clinical Immunology, 111 952-957 (2003) [C1]

Gibson Peter Gerard, Wark Peter Alexander, Simpson Jodie Louise, Meldrum C J, Meldrum S, Saltos Nicholas, Boyle Michael J, ’Induced sputum IL-8 gene expression, neutrophil influx and MMP-9 in allergic bronchopulmonary aspergillosis’, European Respiratory Journal, 21 582-588 (2003) [C1]

Simpson Jodie Louise, Moric Ivana, Wark Peter Alexander, Johnston S, Gibson Peter Gerard, ’Use of induced sputum for the diagnosis of influenza and infections in asthma: a comparison of diagnostic techniques’, Journal of Clinical Virology, 339-346 (2003) [C1]

Wark Peter Alexander, Simpson Jodie Louise, Hensley Michael John, Gibson Peter Gerard, ’Airway inflammation in thunderstorm asthma’, Clinical and Experimental Allergy, 32 1750-1756 (2002) [C1]

Wark Peter Alexander, Johnston Sl, Simpson Jodie Louise, Hensley Michael John, Gibson Peter Gerard, ’Chlamydia pneumoniae immunoglobulin A reactivation and airway inflammation in acute asthma’, The European Respiratory Journal, 20 834-840 (2002) [C1]

Wark Peter Alexander, Johnston Sl, Moric I, Simpson Jodie Louise, Hensley Michael John, Gibson Peter Gerard, ’Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma’, The European Respiratory Journal, 19 68-75 (2002) [C1]

Simpson Jodie Louise, Gibson Peter Gerard, Wark Peter Alexander, ’Optimization of sputum-processing methods for the measurement of interleukin-5: Effects of protease inhibition’, Respirology, 7 111-116 (2002) [C1]

Gibson Peter Gerard, Simpson J, Chalmers Anita Catherine, Toneguzzi R, Wark Peter Alexander, Wilson Amanda Jane, Hensley Michael John, ’Airway Eosinophilia is associated with Wheeze but is uncommon in Children with Persistent Cough and Frequent Chest Colds’, American Journal of Respiratory and Critical Care Medicine, 164 977-981 (2001) [C1]

Wark Peter Alexander, Gibson Peter Gerard, ’Allergic bronchopulmonary aspergillosis: New concepts of pathogenesis and treatment’, Respirology, 6 1-7 (2001) [C2]

Wark Peter Alexander, Gibson Peter Gerard, Johnston S, ’Exacerbations of asthma: addressing the triggers and treatments’, Monaldi Archives for Chest Disease, 56 429-435 (2001) [C1]

Wark Peter Alexander, Simpson J, Hensley Michael John, Gibson Peter Gerard, ’Safety of sputum induction with isotonic saline in adults with acute severe asthma’, Clinical and Experimental Allergy, 31 1745-1753 (2001) [C1]

Wark Peter Alexander, Wilson Aj, Gibson Peter Gerard, ’Azoles for allergic bronchopulmonary aspergillosis’, The Cochrane Library, 1-9 (2000) [C1]

Wark Peter Alexander, Saltos Nicholas, Simpson J, Slater S, Hensley Michael John, Gibson Peter Gerard, ’Induced sputum easinophils and neutrophils and bronchiectasis severity in allergic bronchopulmonary aspergillosis’, European Respiratory Journal, 16 1095-1101 (2000) [C1]

Wark Peter Alexander, Gibson Peter Gerard, Fakes Kellie, ’Induced sputum eosinophils in the assessment of asthma and chronic cough*’, Respirology, 5 51-57 (2000) [C1]

Review

Wark Peter Alexander, Gibson Peter Gerard, Wilson Amanda Jane, ’Azoles for Allergic Bronchopulmonary Aspergillosis Associated With Asthma’, Cochrane Database of Systematic Reviews (2004) [D1]

Conference Publication

Jenkins C R, Marks G B, Gibson Peter Gerard, Wark Peter Alexander, Thien F C K, Belousova E G, Santos C, Reddel H K, ’A randomised controlled trial of two algorithms for maintaining asthma control on long acting bronchodilators (LABA) and inhaled corticosteroids (ICS)’, Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]

Saedi Some Olia Ahmad, Garg Manohar Lal, Wood Lisa Gai, Gibson Peter Gerard, Wark Peter Alexander, ’Anti-inflammatory effect of lycopene enrichment on infected cultured airway epithelial cells’, Respirology (Abstracts of the 12th Congress of the Asian Pacific Society of Respirology), Gold Coast, QLD (2007) [E3]

Wark Peter Alexander, Grissell Terry Vincent, Davies B, Mimica J, Oldham R, Shafren Darren Raymond, Gibson Peter Gerard, ’Bronchial epithelial cell (BEC) response to clinical rhinovirus (clin-RV) isolates from ASTHMATICS compared to laboratory (lab-RV) strains’, American Journal of Respiratory and Critical Care Medicine (American Thoracic Society 2007 International Conference Abstracts), San Francisco (2007) [E3]

Reddel H K, Peters M J, Wark Peter Alexander, Sand I B, Jenkins C R, ’Comparison of the efficacy of seretide and flixotide when down-titrating the inhaled corticosteroid dose’, American Journal of Respiratory and Critical Care Medicine (American Thoracic Society 2007 International Conference Abstracts), San Francisco (2007) [E3]

Xatzipsalti M, Haynes R, Ribbene A, Sones J L, Bagmane D, Wark Peter Alexander, Holgate S T, Davies D E, ’Deficient interferon production following rhinovirus infection of differentiated bronchial epithelial cells from asthmatic subjects’, American Journal of Respiratory and Critical Care Medicine (American Thoracic Society 2007 International Conference Abstracts), San Francisco (2007) [E3]

Ribbene A, Bucchieri F, Wark Peter Alexander, Andrews A L, Puddicombe S M, Zummo G, Holgate S T, Davies D E, ’Epithelial-mesenchymal communication following rhinovirus infection of asthmatic bronchial epithelial cells’, American Journal of Respiratory and Critical Care Medicine (American Thoracic Society 2007 International Conference Abstracts), San Francisco (2007) [E3]

Wark Peter Alexander, Mimica J, Oldham R, Davies D E, Holgate S E, Johnston S, Gibson Peter Gerard, ’Interferon-G induced protein (IP)- 10 is a novel clinical biomarker of rhinovirus (RV)-induced asthma exacerbations’, Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]

Saedi Some Olia Ahmad, Garg Manohar Lal, Wood Lisa Gai, Wark Peter Alexander, Gibson Peter Gerard, ’Lycopene enrichment of cultured epithelial airway cells’, Asia Pacific Journal of Clinical Nutrition, Auckland, New Zealand (2007) [E3]

Wark Peter Alexander, See H V, Oldham R, Timmins N, Gibson Peter Gerard, Hansbro Philip Michael, ’Response by peripheral blood monocytes (PBMCs) to rhinovirus (RV) is greater in cells exposed to infected epithelium in coculture than exposed to RV alone’, American Journal of Respiratory and Critical Care Medicine (American Thoracic Society 2007 International Conference Abstracts), San Francisco (2007) [E3]

Grissell Terry Vincent, Hansbro Nicole Gower, Hsu Alan, Mimica Joanna, Wark Peter Alexander, ’Response of primary bronchoepithelial cells from COPD, asthmatic and healthy subjects to infection with avian and human influenza virus strains’, Respirology (Abstracts of the 12th Congress of the Asian Pacific Society of Respirology), Gold Coast, QLD (2007) [E3]

See Hayley, Oldham R, Timmins N, Hansbro Philip Michael, Wark Peter Alexander, Gibson Peter Gerard, ’Rhinovirus (RV) induced inflammatory response in mononuclear cells is enhanced by coculture with airway epithelium’, Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]

De Groot Romy S, Kuo Curtis, King Nickolas, Moir Lyn, Lim Sam, Burgess Janette K, Wark Peter Alexander, Johnstone Sebastian, Black Judith L, ’Steroids can reverse rhinovirus-induced alterations to bronchial epithhelium extracellular matrix deposition’, Respirology (Abstracts of the 12th Congress of the Asian Pacific Society of Respirology), Gold Coast, QLD (2007) [E3]

Wark Peter Alexander, Wood Lisa Gai, Grissell Terry Vincent, Davies B, Shafren Darren Raymond, Powell Helen Gaye, Hensley Michael John, Gibson Peter Gerard, ’Acute virus-induced asthma is characterised by increased expression of toll-like receptors (TLR)-2’, Respirology, Canberra (2006) [E3]

Grissell Terry Vincent, Davies B, Mimica J L, Shafren Darren Raymond, Gibson Peter Gerard, Wark Peter Alexander, ’Bronchial epithelial cell response to clinical rhinoviruses isolated from asthmatics compared to laboratory rhinovirus strains’, Respirology, Canberra (2006) [E3]

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