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Biomolecular Research Facility

What is the BRF?

The Biomolecular Research Facility was originally established in 1995 as a joint venture between the Faculty of Medicine and Health Sciences, the Faculty of Science and Mathematics, and the Hunter Area Health Service. Its aim was to promote local research by co-ordinating the acquisition of major pieces of equipment. These pieces of equipment were then managed and maintained by expert personnel for use by researchers on a cost-recovery basis.3 units have been established within the BRF since 1995 providing a variety of essential services to local researchers including DNA and protein sequencing, protein characterisation, Flow cytometry and cell sorting.

Funding for the equipment and staffing of the BRF is provided by the Australian Research Council, the National Health and Medical Research Council, the Ramiciotti foundation, Hunter Medical Research Institute and the University of Newcastle.

In 2002 the BRF became a recognised core facility of the University of Newcastle, under the management of the Research and International Division. An Expert Advisory Committee of researchers from the Faculty of Health, Faculty of Science and Information Technology, and the Hunter Medical Research Institute provides research guidance and direction.

Units of the BRF

Follow the links below to discover more about the specialised analyses that each of the units of the BRF can offer to researchers. Please contact the BRF manager initially to obtain further information.

Newcastle DNA	Automated DNA Sequencing
Newcastle FACS	FACSCanto and FACSCaliber Flow Cytometry FACS Aria Cell Sorting
Newcastle Protein	1-D SDS-PAGE 2-D Electrophoresis Electrotransfer & Western Blotting N-terminal and internal Sequencing MALDI-TOF analysis Molecular Interaction Investigation using the Biacore