Research

Reproductive Science Group - Research

Spermatogenesis and Stem Cell Biology


Male germ cells
  • Germ cell homing to the Stem Cell Niche
  • Retention of Spermatogonial Stem cell phenotype
  • Molecular Pathways of Germ Cell Differentiation
  • DNA damage in the Germline
  • Transgenerational toxicity

Mammalian Spermatozoal Biology


Sperm Function
  • Epididymal Transit and Maturation
  • Capacitation and Development of Fertilizing Ability
  • Mitochondrial Function and Reactive Oxygen Species
  • Monotreme sperm biology

Ovarian Biology


Oocytes and Folliculogenesis
  • RNA binding proteins and oocyte development
  • Cytokine signalling and primordial follicle activation
  • Xenobiotics and folliculogenesis

Fertilisation and Contraception


Sperm Oocyte Interaction
  • Formation of Sperm Zona Receptor Complex
  • Oolemma sperm receptors
  • Spermicides and microbicides
  • Depletion of ovarian primordial follicles
  • Environmental impacts on female fertility
  • What Makes a Good Egg?
  • Identification and validation of targets for fertility regulation

Assisted Conception and Early Development


Management of Human Infertility
  • Proteomic and Metabolomic Analyses of Gamete and Embryo quality
  • Epigenetic Defects