The CCEB is in the heart of the city of Newcastle, Australia; in the David Maddison Clinical Sciences Building on the campus of the Royal Newcastle Hospital. It is just a short walk to the city and its beautiful beaches, shopping mall and central train station.

Within the David Maddison Building our postgraduate students have access to the Hunter Area Health Service's Gardiner Library and its extensive facilities. Students also have access to computer facilities and support services within the David Maddison Building, in addition to the full range of facilities provided on the main campus.

The main university campus is located about 12km west in the suburb of Callaghan. It is accessible via public bus and train transport systems. The John Hunter Hospital, the region's main teaching hospital, is also accessible by the public bus transport system.