The Centre for Bioinformatics, Biomarker Discovery and Information-Based Medicine is committed to shortening the process of obtaining novel discoveries to achieve distinctively better outcomes in clinical practice and translational individualised medicine

Priority Research Centre for
BIOINFORMATICS, BIOMARKER DISCOVERY AND INFORMATION-BASED MEDICINE

Research

The Centre for Bioinformatics, Biomarker Discovery and Information-Based Medicine (CIBM) brings together academics from the Faculty of Health and the Faculty of Engineering and Built Environment and works in collaboration with the Hunter Medical Research Institute's Information Based Medicine Program. The Centre draws together the disciplines of bioinformatics, and molecular and genetic analysis with clinical information and population data analysis.

Researchers in the Centre utilise computer technology and mathematical methods to extract meaningful information from vast amounts of clinical and molecular data to identify disease-related genetic patterns. The aim is to inform the development of patient-tailored treatment to a host of diseases which are influenced by genetic aspects, such as breast cancer, prostate cancer, melanoma, schizophrenia and potential applications for chronic obstructive pulmonary disease.

Research Themes

  1. Complex genetics of common diseases
  2. Molecular mechanisms of disease
  3. Artificial intelligence and signal and image processing
  4. Biochemistry and cell biology
  5. Information-based medicine

Cancer Treatment: An Illustrative Example of a Real World Application

There are many challenging issues facing medical practice and none more so than in the field of cancer treatment. Currently, whilst a set of therapies exist for people diagnosed with cancer, some treatments have a broader spectrum of use and others are designed to target specific types of the disease. In addition, those therapies will typically work on some people, while for others they might not work at all. The primary goal is to provide patients with an optimal treatment to maximise their chances of having a good outcome. The Centre's focus on personalised medicine, which individualises patient treatment, maximises benefits and minimises adverse side effects, and potentially saves the healthcare industry millions of dollars in the future.