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Dr Vanessa Murphy

NHMRC Career Development Fellow

School of Medicine and Public Health

Career Summary

Biography

Dr Vanessa Murphy is a postdoctoral research scientist investigating the characteristics, mechanisms and consequences of asthma exacerbations during pregnancy and their health impact on both the mother and the baby. She began in this field full-time in 1999, with her PhD studies on the effects of maternal asthma on placental function and fetal development winning numerous awards, nationally and internationally. In 2004, with a competitive 3 year fellowship from the Hunter Medical Research Institute, she commenced her post-doctoral studies with the Centre for Asthma and Respiratory Diseases, under the supervision of Prof Peter Gibson, where she is continuing to build on her expertise in the area of asthma exacerbations and airway inflammation during pregnancy. Since 2006, Dr Murphy has pursued her research career part-time, and has taken three significant breaks from her career while having children. In 2007 she received her first project grant from the NHMRC, which investigated the mechanisms, characteristics and consequences of viral infections on asthma exacerbations during pregnancy, and she is currently funded by a part-time NHMRC fellowship which was also awarded in 2007. She is involved as an associate investigator on the NHMRC funded “Managing asthma in pregnancy” (MAP) randomised controlled trial, which successfully reduced the rate of severe exacerbations in pregnancy by managing treatment changes with the use of an objective marker of airway inflammation. This resulted in a high impact publication in Lancet in 2011. With pilot funding from HMRI, this study has now been extended to a birth cohort follow-up study, investigating the links between maternal asthma in pregnancy and the development of asthma in childhood, in collaboration with Paediatrician A/Prof Joerg Mattes and Prof Peter Gibson. A further highlight of recent years has been working on an exciting collaboration with the world leader in the field of asthma during pregnancy, Prof Michael Schatz and colleagues in San Diego, USA. Together, we have completed the first systematic review and meta-analysis examining the risks of adverse perinatal outcomes in women with asthma, which has resulted in a publication in the British Journal of Obstetrics and Gynaecology in 2011. Dr Murphy has been invited to write reviews several times, and this year was invited to speak at the European Respiratory Society Conference in Amsterdam in September on the management of asthma during pregnancy, demonstrating her recognition internationally in the field of asthma during pregnancy.

Research Expertise

Vanessa's research expertise is in the area of asthma during pregnancy, covering the effects of asthma on pregnancy outcomes, the management of asthma during pregnancy, and the mechanisms of viral infection in pregnancy. 


Qualifications

  • PhD, University of Newcastle
  • Bachelor of Medicinal Chemistry (Honours), University of Wollongong

Keywords

  • asthma
  • pregnancy

Fields of Research

Code Description Percentage
110299 Cardiorespiratory Medicine and Haematology not elsewhere classified 35
160599 Policy and Administration not elsewhere classified 30
111499 Paediatrics and Reproductive Medicine not elsewhere classified 35

Professional Experience

UON Appointment

Title Organisation / Department
NHMRC Career Development Fellow University of Newcastle
School of Medicine and Public Health
Australia

Academic appointment

Dates Title Organisation / Department
1/12/2007 - 1/03/2013 Australian Part-time Research Fellowship

NHMRC - Early Career Fellowships (Formerly Postdoctoral Training Fellowships)

University of Newcastle
School of Medicine and Public Health
Australia
1/03/2004 -  Post Doctoral Research Fellow University of Newcastle
School of Medicine and Public Health
Australia

Awards

Research Award

Year Award
2005 Young Scientist Sponsorship
European Respiratory Society
2005 Ian Potter Foundation Travel Grant
Ian Potter Foundation
2004 New Investigator Award
Unknown
2003 Elsevier Science New Investigator Award
Unknown
2002 Australian Society for Medical Research (ASMR) Research Award
Unknown
2002 Best Oral Presentation by a Student
Unknown
2001 Medibank Private Student Researcher Award
Unknown
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (3 outputs)

Year Citation Altmetrics Link
2010 Murphy VE, Gibson PG, 'Asthma and rhinitis in pregnancy', Allergy Frontiers: Therapy and Prevention, Springer, Berlin 485-497 (2010) [B1]
Co-authors Peter Gibson
2009 Murphy VE, Gibson PG, 'Asthma in pregnancy', Pulmonary Problems in Pregnancy, Humana Press, New York 143-164 (2009) [B1]
DOI 10.1007/978-1-59745-445-2
Co-authors Peter Gibson
2006 Murphy VE, Smith R, Giles WB, Clifton VL, 'The role of the mother, placenta, and fetus in the control of fetal growth during human pregnancy', Perinatal Programming: Early Life Determinants of Adult Health & Disease, Taylor & Francis, London 3-16 (2006) [B1]
Co-authors Vicki Clifton, Roger Smith

Journal article (47 outputs)

Year Citation Altmetrics Link
2015 Vanders RL, Murphy VE, 'Maternal complications and the management of asthma in pregnancy.', Womens Health (Lond Engl), 11 183-191 (2015)
DOI 10.2217/whe.14.69
2015 Vanders RL, Murphy VE, Gibson PG, Hansbro PM, Wark PAB, 'CD8 T cells and dendritic cells: Key players in the attenuated maternal immune response to influenza infection', Journal of Reproductive Immunology, 107 1-9 (2015)

Pregnancy provides a unique challenge for maternal immunity, requiring the ability to tolerate the presence of a semi-allogeneic foetus, and yet still being capable of inducing an... [more]

Pregnancy provides a unique challenge for maternal immunity, requiring the ability to tolerate the presence of a semi-allogeneic foetus, and yet still being capable of inducing an immune response against invading pathogens. To achieve this, numerous changes must occur in the activity and function of maternal immune cells throughout the course of pregnancy. Respiratory viruses take advantage of these changes, altering the sensitive balance of maternal immunity, leaving the mother with increased susceptibility to viral infections and increased disease severity. Influenza virus is one of the most common respiratory virus infections during pregnancy, leading to an increased risk of ICU hospitalisations, pneumonia, acute respiratory distress syndrome and even death. Whilst much research has been performed to understand the changes that must take place in maternal immunity during pregnancy, considerable work is still needed to fully comprehend this tremendous feat. To date, few studies have focused on the alterations that occur in maternal immunity during respiratory virus infections. This review highlights the role of dendritic cells (DCs) and CD8 T cells during pregnancy, and the changes that occur in these antiviral cells following influenza virus infections.

DOI 10.1016/j.jri.2014.09.051
Co-authors Philip Hansbro, Peter Wark, Peter Gibson
2015 McLaughlin K, Kable A, Ebert L, Murphy VE, 'Barriers preventing Australian midwives from providing antenatal asthma management', British Journal of Midwifery, 23 116-123 (2015)

International guidelines indicate that management of asthma during pregnancy should be multidisciplinary; however, the role of midwives has not been researched. Method: A qualitat... [more]

International guidelines indicate that management of asthma during pregnancy should be multidisciplinary; however, the role of midwives has not been researched. Method: A qualitative descriptive study exploring Australian midwives' current knowledge about asthma in pregnancy and their perceived role in antenatal asthma management was conducted, involving individual semi-structured in-depth interviews with 13 midwives in a tertiary referral hospital. Data were analysed using Morse and Field's four-stage process. Findings: Midwives identified barriers preventing them from providing antenatal asthma management, including: lack of knowledge about asthma in pregnancy; time constraints; women's knowledge about asthma in pregnancy; lack of a clear referral pathway; and lack of accessible asthma management equipment. Barriers were influenced by the institutional context in which the midwives worked. Conclusion: While participants identified barriers preventing them from providing recommended antenatal asthma management, they also suggested that improving their knowledge about asthma in pregnancy and developing a clear referral pathway may be beneficial.

DOI 10.12968/bjom.2015.23.2.116
Co-authors Lyn Ebert, Ashley Kable
2015 Mandaliya PH, Morten M, Kumar R, James A, Deshpande A, Murphy VE, et al., 'Ventilation inhomogeneities in children with congenital thoracic malformations.', BMC Pulm Med, 15 25 (2015)
DOI 10.1186/s12890-015-0023-1
Co-authors Joerg Mattes, Peter Gibson
2015 Thorburn AN, McKenzie CI, Shen S, Stanley D, Macia L, Mason LJ, et al., 'Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites.', Nat Commun, 6 7320 (2015)
DOI 10.1038/ncomms8320
Co-authors Joerg Mattes, Lisa Wood, Peter Gibson
2014 Mattes J, Murphy VE, Powell H, Gibson PG, 'Prenatal origins of bronchiolitis: Protective effect of optimised asthma management during pregnancy', Thorax, 69 383-384 (2014) [C1]

Objective Maternal asthma is the most common chronic disease complicating pregnancy and is a risk factor for bronchiolitis in infancy. Recurrent episodes of bronchiolitis are stro... [more]

Objective Maternal asthma is the most common chronic disease complicating pregnancy and is a risk factor for bronchiolitis in infancy. Recurrent episodes of bronchiolitis are strongly associated with the development of childhood asthma. Methods We conducted a follow-up study of infants born to women with asthma who completed a double-blind randomised controlled trial during pregnancy. In this trial, pregnant women with asthma were assigned to treatment adjustment by an algorithm using clinical symptoms (clinical group) or the fraction of exhaled nitric oxide (FeNO group) and we showed that the FeNO group had significantly lower asthma exacerbation rates in pregnancy. Results 146 infants attended the 12-month follow-up visit. Infants born to mothers from the FeNO group were significantly less likely to have recurrent episodes of bronchiolitis in the first year of life (OR 0.08, 95% CI 0.01 to 0.62; p=0.016) as compared with the clinical group. Conclusions Optimised management of asthma during pregnancy may reduce recurrent episodes of bronchiolitis in infancy, which could potentially modulate the risk to develop or the severity of emerging childhood asthma.

DOI 10.1136/thoraxjnl-2013-203388
Citations Scopus - 6Web of Science - 3
Co-authors Peter Gibson, Joerg Mattes
2014 Murphy VE, Mattes J, Powell H, Baines KJ, Gibson PG, 'Respiratory viral infections in pregnant women with asthma are associated with wheezing in the first 12 months of life', Pediatric Allergy and Immunology, 25 151-158 (2014) [C1]

Background: There are few studies investigating the relationship between respiratory viral infection in pregnancy and asthma in the offspring, and none among mothers with asthma. ... [more]

Background: There are few studies investigating the relationship between respiratory viral infection in pregnancy and asthma in the offspring, and none among mothers with asthma. Infants of mothers with asthma are more likely to wheeze and have a higher risk of developing asthma than infants of non-asthmatic mothers. Methods: A prospective cohort study of viral infection in pregnancy was conducted between 2007 and 2009, and a subgroup of infants of mothers with asthma was followed up at 6 and 12 months of age. During common colds, nasal and throat swabs were collected from mothers and respiratory viruses detected by polymerase chain reaction. Respiratory health of infants was assessed by parent-completed questionnaire. Results: Twelve-month-old infants whose mothers had confirmed viral infections in pregnancy (n = 26) reported more frequent wheeze (40% had 4-12 wheeze attacks compared with 0%), sleep disturbed by wheeze (1 night per week or more in 60% vs. 11%), beta agonist treatment for wheeze (27% vs. 0%), prolonged colds (2 wk or longer 31% vs. 0%), more eczema (40% vs. 6.3%), and parent-perceived asthma (32% vs. 0%), compared with infants whose mothers had common colds without laboratory-confirmed viral infection (n = 16). Conclusions: This study demonstrates a relationship between maternal respiratory viral infection in pregnancy and wheezing illness in infants of mothers with asthma. Viral infections are the most common cause of asthma exacerbations in pregnancy, and infants of asthmatic mothers are at increased risk of asthma themselves. Further research is needed to elucidate the mechanisms involved. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

DOI 10.1111/pai.12156
Citations Scopus - 2Web of Science - 2
Co-authors Katherine Baines, Joerg Mattes, Peter Gibson
2014 Murphy VE, Schatz M, 'Asthma in pregnancy: A hit for two', European Respiratory Review, 23 64-68 (2014) [C1]

Asthma commonly occurs in pregnant females, and recent data have outlined the risks of adverse perinatal outcomes among this population. There is an increased risk of low birth we... [more]

Asthma commonly occurs in pregnant females, and recent data have outlined the risks of adverse perinatal outcomes among this population. There is an increased risk of low birth weight and small for gestational age, particularly among females with moderate-to-severe asthma and exacerbations during pregnancy. There is also an increased risk of preterm birth, especially with oral steroid use, a small but statistically significant increased risk of congenital malformations, particularly of cleft lip with or without cleft palate, and an increased risk of neonatal hospitalisation and death. Active management may reduce these risks, possibly through reductions in exacerbations. Additional reassuring data have been presented for asthma medication use, which support the benefits outweighing the risks of indicated asthma medication use in pregnancy. Viral infections are an important trigger of asthma exacerbations in pregnancy, and recent data provides possible immunological changes that may explain this. Poor medication adherence despite worsening asthma symptoms in pregnancy is a problem which continues to be demonstrated in the literature. Improving asthma control in pregnancy has the potential to improve not only the mother's health but also that of her child. © ERS 2014.

DOI 10.1183/09059180.00008313
Citations Scopus - 3
2014 Wark PAB, Murphy V, Mattes J, 'The interaction between mother and fetus and the development of allergic asthma', Expert Review of Respiratory Medicine, 8 57-66 (2014) [C1]

The rising prevalence of asthma and atopic disease in industrialized countries in the last 50 years has raised important questions about how and why the disease develops in suscep... [more]

The rising prevalence of asthma and atopic disease in industrialized countries in the last 50 years has raised important questions about how and why the disease develops in susceptible populations. Most asthma begins in childhood in association with allergic sensitization and the development of a TH2 phenotype. It is recognized that asthma arises in the context of a complex interaction between genetic factors and the evolving immune system of the infant and the environment to which it is exposed, which now includes its in utero exposure. Early life exposures that lead to allergen sensitization and airway damage, especially in the form of viral respiratory tract infections, may lead to disease induction that commence the process that leads in some to asthma. Asthma models and early life observations suggest that repeated exposure to allergens and viral infection perpetuate a state of chronic airway inflammation leading to a maladaptive innate immune response that fails to resolve, characterized by chronic airway inflammation, airway remodeling and airway hyperresponsiveness. This article will concentrate on the development of asthma in the context of early life and maternal influences, including the effect of asthma on both the fetus and the mother. © 2014 Informa UK Ltd.

DOI 10.1586/17476348.2014.848795
Citations Scopus - 4Web of Science - 4
Co-authors Peter Wark, Joerg Mattes
2014 Gunawardhana LP, Baines KJ, Mattes J, Murphy VE, Simpson JL, Gibson PG, 'Differential DNA methylation profiles of infants exposed to maternal asthma during pregnancy', Pediatric Pulmonology, 49 852-862 (2014) [C1]

Background Asthma is a complex disease that involves both genetic factors and environmental exposures. Aberrant epigenetic modifications, such as DNA methylation, may be important... [more]

Background Asthma is a complex disease that involves both genetic factors and environmental exposures. Aberrant epigenetic modifications, such as DNA methylation, may be important in asthma development. Fetal exposure to maternal asthma during critical periods of in utero development may lead to epigenetic alterations that predispose infants to a greater risk of developing asthma themselves. We investigated alterations in the DNA methylation profile of peripheral blood from infants exposed to maternal asthma during pregnancy. Methods Peripheral blood was collected from 12-month-old infants born to women with (n = 25) and without (n = 15) doctor diagnosed asthma during pregnancy. Genomic DNA was extracted, bisulfite converted, and hybridized to Infinium Methylation 27 arrays (Illumina), containing over27,000 CpGs from 14,495 genes. CpG loci in only autosomal genes were classified as differentially methylated at the 99% level (P < 0.01, |DiffScore| > 22 and delta beta >0.06). Results There were 70 CpG loci, corresponding to 67 genes that were significantly differentially methylated. Twelve CpG loci (11 genes) showed greater than 10% comparative difference in DNA methylation, including hyper-methylated loci of FAM181A, MRI1, PIWIL1, CHFR, DEFA1, MRPL28, AURKA, and hypo-methylated loci of NALP1L5, MAP8KIP3, ACAT2, and PM20D1 in maternal asthma. Methylation of MAPK8IP3 was significantly negatively correlated with maternal blood eosinophils (r = -0.38; P = 0.022), maternal eNO (r = -0.44; P = 0.005), and maternal serum total IgE (r = -0.39, P = 0.015). Methylation of AURKA negatively correlated with maternal hemoglobin (r = -0.43; P = 0.008), infants height (r = -0.51; P < 0.001) and weight (r = -0.36; P = 0.021). Methylation of PM20D1 was lower in infants born to mothers with asthma on inhaled corticosteroid treatment. Methylation of PM20D1 was lower and MRI1 was higher in infants born to atopic mothers without asthma. Conclusions In an Australian study population, exposure to maternal asthma during pregnancy is associated with differential methylation profiles of infants' peripheral blood DNA, which may act as risk factors for future asthma development. © 2013 Wiley Periodicals, Inc.

DOI 10.1002/ppul.22930
Citations Scopus - 3Web of Science - 2
Co-authors Jodie Simpson, Joerg Mattes, Peter Gibson, Katherine Baines
2014 Wang G, Murphy VE, Namazy J, Powell H, Schatz M, Chambers C, et al., 'The risk of maternal and placental complications in pregnant women with asthma: A systematic review and meta-analysis', Journal of Maternal-Fetal and Neonatal Medicine, 27 934-942 (2014) [C1]

Objective: To investigate if maternal asthma is associated with an increased risk of maternal and placental complications in pregnancy. Methods: Electronic databases were searched... [more]

Objective: To investigate if maternal asthma is associated with an increased risk of maternal and placental complications in pregnancy. Methods: Electronic databases were searched for the following terms: (asthma or wheeze) and (pregnan* or perinat* or obstet*). Cohort studies published between January 1975 and March 2012 were considered for inclusion. Forty publications met the inclusion criteria, reporting at least one maternal or placental complication in pregnant women with and without asthma. Relative risk (RR) with 95% confidence intervals (CIs) was calculated. Results: Maternal asthma was associated with a significantly increased risk of cesarean section (RR=1.31, 95%CI=[1.22-1.39]), gestational diabetes (RR=1.39, 95%CI=[1.17-1.66]), hemorrhage (antepartum: RR=1.25, 95%CI=[1.10-1.42]; postpartum: RR=1.29, 95%CI=[1.18-1.41]), placenta previa (RR=1.23, 95%CI=[1.07-1.40]), placental abruption (RR=1.29, 95%CI=[1.14-1.47]) and premature rupture of membranes (RR=1.21, 95%CI=1.07-1.37). Moderate to severe asthma significantly increased the risk of cesarean section (RR=1.19, 95%CI=[1.09-1.31]) and gestational diabetes (RR=1.19, 95%CI=[1.06-1.33]) compared to mild asthma. Bronchodilator use was associated with a significantly lowered risk of gestational diabetes (RR=0.64, 95%CI=[0.57-0.72]). Conclusions: Pregnant women with asthma are at increased risk of maternal and placental complications, and women with moderate/severe asthma may be at particular risk. Further studies are required to elucidate whether adequate control of asthma during pregnancy reduces these risks. © 2014 Informa UK Ltd. All rights reserved.

DOI 10.3109/14767058.2013.847080
Citations Scopus - 5Web of Science - 4
Co-authors John Attia, Peter Gibson
2013 Murphy VE, Powell H, Wark PAB, Gibson PG, 'A Prospective Study of Respiratory Viral Infection in Pregnant Women With and Without Asthma', CHEST, 144 420-427 (2013) [C1]
DOI 10.1378/chest.12-1956
Citations Scopus - 7Web of Science - 3
Co-authors Peter Gibson, Peter Wark
2013 Vanders RL, Gibson PG, Murphy VE, Wark PAB, 'Plasmacytoid Dendritic Cells and CD8 T Cells From PregnantWomen Show Altered Phenotype and Function Following H1N1/09 Infection', JOURNAL OF INFECTIOUS DISEASES, 208 1062-1070 (2013) [C1]
DOI 10.1093/infdis/jit296
Citations Scopus - 5Web of Science - 5
Co-authors Peter Gibson, Peter Wark
2013 Powell H, McCaffery K, Murphy VE, Hensley MJ, Clifton VL, Giles W, Gibson PG, 'Psychosocial Variables Are Related to Future Exacerbation Risk and Perinatal Outcomes in Pregnant Women with Asthma', JOURNAL OF ASTHMA, 50 383-389 (2013) [C1]
DOI 10.3109/02770903.2012.757777
Citations Scopus - 7Web of Science - 5
Co-authors Michael Hensley, Peter Gibson
2013 Namazy JA, Murphy VE, Powell H, Gibson PG, Chambers C, Schatz M, 'Effects of asthma severity, exacerbations and oral corticosteroids on perinatal outcomes', EUROPEAN RESPIRATORY JOURNAL, 41 1082-1090 (2013) [C1]
DOI 10.1183/09031936.00195111
Citations Scopus - 20Web of Science - 15
Co-authors Peter Gibson
2013 Vanders RL, Gibson PG, Wark PAB, Murphy VE, 'Alterations in inflammatory, antiviral and regulatory cytokine responses in peripheral blood mononuclear cells from pregnant women with asthma', RESPIROLOGY, 18 827-833 (2013) [C1]
DOI 10.1111/resp.12068
Citations Scopus - 7Web of Science - 4
Co-authors Peter Wark, Peter Gibson
2013 Murphy VE, Wang G, Namazy JA, Powell H, Gibson PG, Chambers C, Schatz M, 'The risk of congenital malformations, perinatal mortality and neonatal hospitalisation among pregnant women with asthma: a systematic review and meta-analysis', BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 120 812-822 (2013) [C1]
DOI 10.1111/1471-0528.12224
Citations Scopus - 16Web of Science - 13
Co-authors Peter Gibson
2013 Giles W, Murphy V, 'Asthma in pregnancy: a review', Obstetric Medicine: The Medicine of Pregnancy, 6 58-63 (2013) [D1]
DOI 10.1258/om.2012.120008
2012 Vanders RL, Wark PA, Murphy VE, Gibson PG, 'Pregnant women have attenuated innate interferon responses to 2009 pandemic influenza a virus subtype H1N1', Journal of Infectious Diseases, 206 646-653 (2012) [C1]
Citations Scopus - 15Web of Science - 14
Co-authors Peter Wark, Peter Gibson
2012 Vanders RL, Gibson PG, Murphy VE, Wark PAB, 'Impaired type I and III interferon response to rhinovirus infection during pregnancy and asthma', Thorax, 67 209-214 (2012) [C1]
Citations Scopus - 28Web of Science - 22
Co-authors Peter Gibson, Peter Wark
2012 McLernon PC, Wood LG, Murphy VE, Hodyl NA, Clifton VL, 'Circulating antioxidant profile of pregnant women with asthma', Clinical Nutrition, 31 99-107 (2012) [C1]
Citations Scopus - 7Web of Science - 6
Co-authors Vicki Clifton, Lisa Wood
2012 Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia JR, Gibson PG, 'Severity of asthma in pregnancy affects perinatal outcomes - Authors' Reply', BJOG - An International Journal of Obstetrics and Gynaecology, 119 508-509 (2012) [C3]
DOI 10.1111/j.1471-0528.2011.03258.x
Co-authors John Attia, Peter Gibson
2012 McLernon PC, Wood LG, Murphy VE, Hodyl NA, Clifton VL, 'Fatty acid profile of pregnant women with asthma', e-SPEN Journal, 7 e78-e85 (2012) [C1]
DOI 10.1016/j.clnme.2012.01.004
Co-authors Lisa Wood, Vicki Clifton
2011 Powell GH, Murphy VE, Taylor DR, Hensley MJ, McCaffery K, Giles W, et al., 'Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: A double-blind, randomised controlled trial', The Lancet, 378 983-990 (2011) [C1]
DOI 10.1016/s0140-6736(11)60971-9
Citations Scopus - 98Web of Science - 83
Co-authors Michael Hensley, Peter Gibson
2011 Murphy VE, Gibson PG, 'Asthma in pregnancy', Clinics in Chest Medicine, 32 93-110 (2011) [C1]
Citations Scopus - 20Web of Science - 12
Co-authors Peter Gibson
2011 Powell H, McCaffery K, Murphy VE, Hensley MJ, Clifton VL, Giles WB, Gibson PG, 'Psychosocial outcomes are related to asthma control and quality of life in pregnant women with asthma', Journal of Asthma, 48 1032-1040 (2011) [C1]
DOI 10.3109/02770903.2011.631239
Citations Scopus - 19Web of Science - 15
Co-authors Peter Gibson, Michael Hensley
2011 Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia JR, Gibson PG, 'A meta-analysis of adverse perinatal outcomes in women with asthma', BJOG: An International Journal of Obstetrics and Gynaecology, 118 1314-1323 (2011) [C1]
DOI 10.1111/j.1471-0528.2011.03055.x
Citations Scopus - 68Web of Science - 57
Co-authors John Attia, Peter Gibson
2010 Murphy VE, Clifton VL, Gibson PG, 'The effect of cigarette smoking on asthma control during exacerbations in pregnant women', Thorax, 65 739-744 (2010) [C1]
DOI 10.1136/thx.2009.124941
Citations Scopus - 21Web of Science - 17
Co-authors Peter Gibson, Vicki Clifton
2010 Hodyl NA, Wyper HJ, Osei-Kumah A, Scott NM, Murphy VE, Gibson PG, et al., 'Sex-specific associations between cortisol and birth weight in pregnancies complicated by asthma are not due to differential glucocorticoid receptor expression', Thorax, 65 677-683 (2010) [C1]
DOI 10.1136/thx.2009.123091
Citations Scopus - 16Web of Science - 13
Co-authors Roger Smith, Peter Gibson, Vicki Clifton
2010 Clifton VL, Hodyl NA, Murphy VE, Giles WB, Baxter RC, Smith R, 'Effect of maternal asthma, inhaled glucocorticoids and cigarette use during pregnancy on the newborn insulin-like growth factor axis', Growth Hormone and IGF Research, 20 39-48 (2010) [C1]
DOI 10.1016/j.ghir.2009.07.004
Citations Scopus - 18Web of Science - 15
Co-authors Roger Smith, Vicki Clifton
2009 Scott NM, Hodyl NA, Murphy VE, Osei-Kumah A, Wyper H, Hodgson DM, et al., 'Placental cytokine expression covaries with maternal asthma severity and fetal sex', Journal of Immunology, 182 1411-1420 (2009) [C1]
Citations Scopus - 37Web of Science - 33
Co-authors Roger Smith, Deborah Hodgson, Vicki Clifton
2008 Johnson RF, Rennie N, Murphy VE, Zakar T, Clifton VL, Smith R, 'Expression of glucocorticoid receptor messenger ribonucleic acid transcripts in the human placenta at term', Journal of Clinical Endocrinology & Metabolism, 93 4887-4893 (2008) [C1]
DOI 10.1210/jc.2008-1077
Citations Scopus - 21Web of Science - 19
Co-authors Roger Smith, Vicki Clifton
2008 Murphy VE, Gibson PG, 'Premenstrual asthma: Prevalence, cycle-to-cycle variability and relationship to oral contraceptive use and menstrual symptoms', Journal of Asthma, 45 696-704 (2008) [C1]
DOI 10.1080/02770900802207279
Citations Scopus - 16Web of Science - 11
Co-authors Peter Gibson
2007 Murphy VE, Fittock RJ, Zarzycki PK, Delahunty MM, Smith R, Clifton VL, 'Metabolism of synthetic steroids by the human placenta', Placenta, 28 39-46 (2007) [C1]
DOI 10.1016/j.placenta.2005.12.010
Citations Scopus - 39Web of Science - 30
Co-authors Roger Smith, Vicki Clifton
2006 Murphy VE, Clifton VL, Gibson PG, 'Asthma exacerbations during pregnancy: incidence and association with adverse pregnancy outcomes', Thorax, 61 169-176 (2006) [C1]
DOI 10.1136/thx.2005.049718
Citations Scopus - 114Web of Science - 102
Co-authors Vicki Clifton, Peter Gibson
2006 Murphy VE, Smith R, Giles WB, Clifton VL, 'Endocrine regulation of human fetal growth: The role of the mother, placenta, and fetus', Endocrine Reviews, 27 141-169 (2006) [C1]
DOI 10.1210/er.2005-0011
Citations Scopus - 227Web of Science - 195
Co-authors Vicki Clifton, Roger Smith
2006 Murphy VE, Johnson RF, Wang YC, Akinsanya K, Gibson PG, Smith R, Clifton VL, 'Proteomic study of plasma proteins in pregnant women with asthma', Respirology, 11 41-48 (2006) [C1]
DOI 10.1111/j.1440-1843.2006.00782.x
Citations Scopus - 20Web of Science - 18
Co-authors Peter Gibson, Vicki Clifton, Roger Smith
2006 Clifton VL, Rennie N, Murphy VE, 'Effect of inhaled glucocorticoid treatment on placental 11 beta-hydroxysteroid dehydrogenase type 2 activity and neonatal birthweight in pregnancies complicated by asthma', Australian and New Zealand Journal of Obstetrics and Gynaecology, 46 136-140 (2006) [C1]
DOI 10.1111/j.1479-828X.2006.00543.x
Citations Scopus - 41Web of Science - 31
Co-authors Vicki Clifton
2005 Murphy VE, Gibson PG, Smith R, Clifton VL, 'Asthma during pregnancy: mechanisms and treatment implications', European Respiratory Journal, 25 731-750 (2005) [C1]
DOI 10.1183/09031936.05.00085704
Citations Scopus - 81Web of Science - 65
Co-authors Roger Smith, Peter Gibson, Vicki Clifton
2005 Murphy VE, Gibson PG, Talbot PI, Kessell CG, Clifton VL, 'Asthma self-management skills and the use of asthma education during pregnancy', European Respiratory Journal, 26 435-441 (2005) [C1]
DOI 10.1183/09031936.05.00135604
Citations Scopus - 43Web of Science - 32
Co-authors Vicki Clifton, Peter Gibson
2005 Murphy VE, Johnson RF, Wang Y-C, Akinsanya K, Gibson PG, Smith R, Clifton VL, 'The Effect of Maternal Asthma on Placental and Cord Blood Protein Profiles', Society for Gynecological Investigation Journal, 12 349-355 (2005) [C1]
DOI 10.1016/j.jsgi.2005.01.024
Citations Scopus - 16Web of Science - 15
Co-authors Vicki Clifton, Peter Gibson, Roger Smith
2005 Murphy VE, Gibson PG, Talbot PI, Clifton VL, 'Severe asthma exacerbations during pregnancy', Obstetrics and Gynecology, 106 1046-1054 (2005) [C1]
Co-authors Vicki Clifton, Peter Gibson
2004 Clifton VL, Murphy VE, 'Maternal Asthma as a Model for Examining Fetal Sex-specific Effects on Maternal Physiology and Placental Mechanisms that Regulate Human Fetal Growth', Placenta, 18 S45-S52 (2004) [C1]
DOI 10.1016/j.placenta.2004.01.004
Citations Web of Science - 63
Co-authors Vicki Clifton
2003 Murphy VE, Clifton VL, 'Alterations in human placental 11 beta-hydroxysteroid dehydrogenase type 1 and 2 with gestational age and labour', Placenta, 24 739-744 (2003) [C1]
DOI 10.1016/S0143-4004(03)00103-6
Citations Scopus - 64Web of Science - 59
Co-authors Vicki Clifton
2003 Murphy VE, Gibson PG, Giles WB, Zakar T, Smith R, Bisits AM, et al., 'Maternal Asthma Is Associated with Reduced Female Fetal Growth', American Journal of Respiratory & Critical Care Medicine, 168 1317-1323 (2003) [C1]
DOI 10.1164/rccm.200303-374OC
Citations Scopus - 127Web of Science - 119
Co-authors Peter Gibson, Roger Smith, Vicki Clifton
2002 Murphy VE, Zakar T, Smith R, Giles WB, Gibson PG, Clifton VL, 'Reduced 11 -Hydroxysteroid Dehydrogenase Type 2 Activity Is Associated with Decreased Birth Weight Centile in Pregnancies Complicated by Asthma', The Journal of Clinical Endocrinology & Metabolism, 87(4) 1660-1668 (2002) [C1]
Citations Scopus - 91Web of Science - 88
Co-authors Peter Gibson, Roger Smith, Vicki Clifton
2000 Clifton VL, Qing G, Murphy VE, Schwartz J, Madsen GM, Smith R, 'Localization and Characterization of Urocortin during Human Pregancy', Placenta, 21 782-788 (2000) [C1]
Citations Scopus - 44Web of Science - 39
Co-authors Roger Smith, Vicki Clifton, Gemma Madsen
Show 44 more journal articles

Conference (61 outputs)

Year Citation Altmetrics Link
2013 Mattes J, Murphy V, Powell H, Gibson P, 'THE EFFECT OF BETTER ASTHMA CONTROL IN PREGNANCY ON WHEEZY ILLNESSES IN INFANCY', RESPIROLOGY (2013) [E3]
Citations Web of Science - 1
Co-authors Joerg Mattes, Peter Gibson
2013 Forbes RL, Gibson PG, Murphy VE, Wark PA, 'H1N1PDM09 ALTERS MATERNAL IMMUNITY DURING PREGNANCY', RESPIROLOGY (2013) [E3]
Co-authors Peter Wark, Peter Gibson
2013 Gunawardhana LP, Baines KJ, Mattes J, Murphy VE, Simpson JL, Gibson PG, 'EPIGENETIC ALTERATIONS IN INFANTS ASSOCIATED WITH MATERNAL ASTHMA DURING PREGNANCY', RESPIROLOGY (2013) [E3]
Co-authors Joerg Mattes, Peter Gibson, Jodie Simpson, Katherine Baines
2012 Powell HG, McCaffery K, Murphy VE, Giles W, Clifton VL, Hensley MJ, Gibson PG, 'Psychosocial outcomes are related to future exacerbation risk and perinatal outcomes in pregnant women with asthma', Respirology, Canberra, ACT (2012) [E3]
Citations Web of Science - 1
Co-authors Vicki Clifton, Peter Gibson, Michael Hensley
2011 Clifton VL, McLernon PC, Wood LG, Murphy VE, Stark MJ, Hodyl NA, 'What do women eat during pregnancy?', Journal of Developmental Origins of Health and Disease, Portland, Oregon (2011) [E3]
Co-authors Lisa Wood
2011 Namazy JA, Murphy VE, Powell H, Gibson PG, Chambers C, Schatz M, 'Effects of asthma severity and medication use on prematurity and intrauterine growth: A meta analysis from published data', Journal of Allergy and Clinical Immunology, San Francisco, CA (2011) [E3]
Co-authors Peter Gibson
2011 Clifton V, McLernon P, Wood LG, Murphy VE, Hodyl N, 'What do pregnant women eat?', Placenta: Abstracts of the IFPA Meeting 2011, Geilo, Norway (2011) [E3]
Co-authors Lisa Wood
2011 Gibson PG, Powell H, Giles W, Clifton V, Hensley MJ, Taylor DR, et al., 'Asthma exacerbations during pregnancy are reduced by inflammometry (FENO) guided asthma management: A randomised controlled trial', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authors Peter Gibson, Michael Hensley
2011 McLaughlin KM, Mattes J, Murphy VE, Steel KR, Powell H, Gibson PG, 'The Growing Into Asthma (GIA) Study: Need for improved management of respiratory illnesses in early life', PSANZ 2011 15th Annual Congress: Poster Abstracts, Hobart, TAS (2011) [E3]
Co-authors Joerg Mattes, Peter Gibson
2011 Vanders RL, Gibson PG, Murphy VE, Wark PA, 'Reduced antiviral interferons during pregnancy explains susceptibility to influenza virus infection', Respirology, Perth, WA (2011) [E3]
Co-authors Peter Wark, Peter Gibson
2011 Gunawardhana LP, Baines KJ, Simpson JL, Mattes J, Murphy VE, Gibson PG, 'Maternal asthma is associated with alterations in DNA methylation profile of peripheral blood of infants', Respirology, Perth, WA (2011) [E3]
Co-authors Katherine Baines, Jodie Simpson, Peter Gibson, Joerg Mattes
2011 Mattes J, Murphy VE, McLaughlin KM, Steel KR, Powell H, Gibson PG, 'Are maternal asthma exacerbations during pregnancy related to impaired infant growth in the first six months of life?', Respirology, Perth, WA (2011) [E3]
Co-authors Peter Gibson, Joerg Mattes
2010 Murphy VE, Namazy JA, Powell GH, Gibson PG, Chambers C, Attia JR, Schatz M, 'A meta-analysis of adverse perinatal outcomes in asthmatic women: Effect of asthma on placental and neonatal outcomes', American Journal of Respiratory and Critical Care Medicine, New Orleans (2010) [E3]
Co-authors John Attia, Peter Gibson
2010 Namazy JA, Murphy VE, Powell HG, Gibson PG, Chambers CD, Schatz M, 'Congenital anomalies in asthmatic women using corticosteroids during pregnancy: A meta analysis from published data', Birth Defects Research (Part A), Louisville, KT (2010) [E3]
Co-authors Peter Gibson
2010 McLernon PC, Murphy VE, Wood LG, Dekker GA, Hodyl NA, Clifton VL, 'Maternal plasma circulating levels of omega (n)3 long chain polyunsaturated fatty acids, eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA) are associated with fetal growth measures', The Endocrine Society of Australia Annual Scientific Meeting Proceedings and Abstract Book, Sydney (2010) [E3]
Co-authors Lisa Wood, Vicki Clifton
2010 Namazy JA, Murphy VE, Powell HG, Gibson PG, Chambers C, Schatz M, 'Adverse perinatal outcomes in asthmatic women: A meta analysis from published data', Journal of Allergy and Clinical Immunology, New Orleans, LA (2010) [E3]
Co-authors Peter Gibson
2010 McLernon PC, Wood LG, Murphy VE, Dekker GA, Clifton VL, 'Maternal circulating levels of omega (N)3 long chain polyunsaturated fatty acids, eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaunoic acid (DHA) during early pregnancy are associated with detal growth meaures in later pregnancy', Placenta, Kumamoto, Japan (2010) [E3]
Co-authors Vicki Clifton, Lisa Wood
2010 Vanders RL, Gibson PG, Murphy VE, Wark PA, 'Reduced anti-viral responses: Why pregnant women have increased susceptibility to respiratory virus infection', American Journal of Respiratory and Critical Care Medicine, New Orleans, LO (2010) [E3]
Co-authors Peter Gibson, Peter Wark
2010 Vanders RL, Gibson PG, Murphy VE, Wark PA, 'Reduced anti-viral responses: Why pregnant women have increased susceptiblty to respiratory virus infection', Respirology, Brisbane, QLD (2010) [E3]
Co-authors Peter Wark, Peter Gibson
2010 Murphy VE, Namazy J, Powell GH, Gibson PG, Chambers C, Attia JR, Schatz M, 'A meta-analysis of adverse perinatal outcomes in asthmatic women: Effect of asthma on maternal and neonatal outcomes', Respirology, Brisbane, QLD (2010) [E3]
Co-authors John Attia, Peter Gibson
2010 Murphy VE, Namazy J, Powell GH, Schatz M, Chambers C, Attia JR, Gibson PG, 'A meta-analysis of adverse perinatal outcomes in asthmatic women: Effect of asthma on size at birth and timing of birth', Respirology, Brisbane, QLD (2010) [E3]
Co-authors Peter Gibson, John Attia
2009 Murphy VE, Clifton VL, Gibson PG, 'The effect of cigarette smoking on asthma control and exacerbations in pregnant women', Respirology, Darwin, NT (2009) [E3]
DOI 10.1111/j.1440-1843.2009.01503_1.x
Co-authors Peter Gibson
2009 Powell H, Murphy VE, Gibson PG, 'The relationship between feno and atopic status in pregnant women with asthma', Respirology, Darwin, NT (2009) [E3]
DOI 10.1111/j.1440-1843.2009.01503_1.x
Co-authors Peter Gibson
2009 McLaughlin KM, Murphy VE, McCaffery K, Powell H, Clifton VL, Giles W, et al., 'The relationship between patient perceived risk of inhaled corticosteroids in pregnancy and medication adherence', Respirology, Darwin, NT (2009) [E3]
Co-authors Peter Gibson, Michael Hensley
2008 Murphy VE, Clifton VL, Gibson PG, 'Characterization of asthma control and airway inflammation during exacerbations in pregnancy', American Journal of Respiratory and Critical Care Medicine, Toronto, ONT (2008) [E3]
Co-authors Peter Gibson, Vicki Clifton
2008 McLernon PC, Wood LG, Murphy VE, Dekker GA, Clifton VL, 'Maternal circulating antioxidant levels in pregnancies complicated by asthma', 51st Annual Scientific Meeting of the Endocrine Society of Australia and Society of Reproductive Biology: Meeting Proceedings and Abstract Book, Melbourne, VIC (2008) [E3]
Co-authors Lisa Wood
2008 Hodyl N, Wyper H, Scott NM, Osei-Kumah A, Murphy VE, Smith R, Clifton VL, 'Relationship between placental glucocorticoid receptor expression and fetal growth in pregnancies complicated by asthma', 51st Annual Scientific Meeting of the Endocrine Society of Australia and Society of Reproductive Biology: Meeting Proceedings and Abstract Book, Melbourne, VIC (2008) [E3]
Co-authors Roger Smith, Vicki Clifton
2008 McLaughlin K, Murphy VE, McCaffery K, Powell H, Clifton V, Giles W, et al., 'The relationship between patient perceived risk of inhaled corticosteroids in pregnancy and medication adherence', Australian Asthma Conference 2008: Conference Program & Abstract Book, Sydney, NSW (2008) [E3]
Co-authors Peter Gibson
2007 Murphy VE, Clifton VL, Gibson PG, 'Fractional exhaled nitric oxide (FENO) in pregnant women with and without asthma', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]
Co-authors Peter Gibson, Vicki Clifton
2006 Micallef MA, Garg ML, Wood LG, Murphy VE, Clifton VL, 'Dietry intake of long chain n-3 polyunsaturated fatty acids in adults with asthma', Asia Pacific Journal of Clinical Nutrition, Sydney, New South Wales (2006) [E3]
Co-authors Manohar Garg, Vicki Clifton, Lisa Wood
2006 Scott NM, Wyper HJ, Osei-Kumah A, Smith R, Murphy VE, Clifton VL, 'Sex specific differences in placental cytokine expression and their relationship to fetal glucocorticoid exposure', Journal of the Society for Gynecologic Investigation. Scientific Program and Abstracts 53rd Annual Meeting, Toronto, Ontario (2006) [E3]
Co-authors Vicki Clifton, Roger Smith
2005 Murphy VE, Clifton VL, Talbot PI, Gibson PG, 'Severe asthma exacerbations during pregnancy', Perinatal Society of Australia and New Zealand 9th Annual Congress, Adelaide, 13-16 March, 2005, Adelaide (2005) [E3]
Citations Web of Science - 84
Co-authors Peter Gibson, Vicki Clifton
2005 Murphy VE, Clifton VL, Gibson PG, 'Asthma exacerbations during pregnancy are associated with low birth weight', European Respiratory Journal, Switzerland (2005) [C3]
Co-authors Peter Gibson, Vicki Clifton
2005 Wynne OL, Clifton VL, Murphy VE, Hodyl NA, Krivanek K, Smith D, et al., 'The Effects of Prenatal Endotoxin Exposure on Placental 11-HSD2 Activity and the Developing HPA Axis in the Fischer 344 Rat', Australian Neuroscience Society: Proceedings of the 25th Annual, Perth, Australia (2005) [E3]
Co-authors Vicki Clifton, Deborah Hodgson, Philip Hansbro, Olivia Wynne
2005 Murphy VE, Talbot PI, Clifton VL, Gibson PG, 'Severe asthma exacerbations during pregnancy', American Journal of Respiratory and Critical Care, New York (2005) [C3]
Co-authors Peter Gibson, Vicki Clifton
2005 Murphy VE, Clifton VL, Talbot PI, Gibson PG, 'Self-management education for pregnant women with asthma', American Journal of Respiratory and Critical Care Medicine, New York (2005) [C3]
Co-authors Vicki Clifton, Peter Gibson
2005 Gibson PG, Giles WB, Zakar T, Smith R, Kessell CG, Clifton VL, Murphy VE, 'Inflammatory factors have sex-specified effects on fetal growth in humans', Ceska Gynekologie, Czech Republic (2005) [C3]
Co-authors Peter Gibson, Roger Smith, Vicki Clifton
2005 Murphy VE, Talbot PI, Clifton VL, Gibson PG, 'Severe asthma exacerbations during pregnancy', Respirology, Philadelphia (2005) [C3]
DOI 10.1097/01.AOG.0000185281.21716.02
Co-authors Peter Gibson, Vicki Clifton
2005 Murphy VE, Clifton VL, Talbot PI, Gibson PG, 'Self-management education for pregnant women with asthma. Thoracic Society of Australia and New Zealand Annual Scientific Meeting, Perth, 18-23 March, 2005', Respirology, - (2005) [C3]
Co-authors Peter Gibson, Vicki Clifton
2005 Murphy VE, Talbot PI, Gibson PG, 'The prevalence and cycle to cycle variability of premenstrual asthma', Respirology, Hoboken (2005) [C1]
DOI 10.1111/j.1440-1843.2005.00663.x-i1
Co-authors Peter Gibson
2005 Fittock R, Murphy VE, Smith R, Zarzycki PK, Clifton VL, 'Metabolism of synthetic glucocorticoids used for the treatment of asthma by placental 11beta-hydoxysteroid dehydrogenase 2', Endocrine Society of Australia Annual Scientific Meeting, Adelaide, 22-25 Sept, 2002, Adelaide (2005) [E3]
Co-authors Roger Smith, Vicki Clifton
2005 Clifton VL, Murphy VE, Gibson PG, Smith R, Giles WB, Scott N, 'Gender specific differences in response to changes in glucocorticoid concentration in the human fetus: Relationship to birthweight', PEDIATRIC RESEARCH, Toronto, CANADA (2005)
Co-authors Peter Gibson, Roger Smith
2004 Clifton VL, Murphy VE, Osei-Kumah A, Giles WB, Smith R, Gibson PG, 'Gender specific mechanisms of human fetal cortisol metabolism and immunity.', JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, Houston, TX (2004)
Co-authors Roger Smith, Peter Gibson
2004 Gibson PG, Murphy VE, Kessell CG, Talbot PI, Giles WB, Smith R, Clifton VL, 'Effect of fetal gender on maternal athsma during pregnancy', American Journal of Respiratory Care, Not Known (2004) [C3]
Co-authors Roger Smith, Peter Gibson, Vicki Clifton
2004 Talbot PI, Murphy VE, Kessell CG, Giles WB, Smith R, Gibson PG, Clifton VL, 'Effect of fetal gender on maternal asthma during pregnancy', Respirology, Australia (2004) [C3]
Co-authors Roger Smith, Peter Gibson, Vicki Clifton
2004 Clifton VL, Murphy VE, Giles WB, 'Gender specific mechanisms of human fetal cortisol metabolism and immunity', Reproductive Sciences, United States (2004) [C3]
Co-authors Vicki Clifton
2004 Johnson RF, Mitchell CM, Murphy VE, Wang Y, Akinsanya K, Smith R, Zakar T, 'Proteomic analyss of proteins in the human amnion during late gestation and labor', reproductive Sciences, United States (2004) [C3]
Co-authors Roger Smith
2004 Murphy VE, Kessell CG, Talbot PI, Gibson PG, Clifton VL, 'Asthma education, lung function and inflammation in pregnant women: relation to birth weight', 8th Annual Conference of the Perinatal Society of Australia and New Zealand, Sydney, 15-19 March, 2004, Sydney (2004) [E3]
Co-authors Vicki Clifton, Peter Gibson
2004 Clifton VL, Murphy VE, Gibson PG, 'Gender specific growth mechanisms in the human fetus', 8th Annual Conference of the Perinatal Society of Australia and New Zealand, Sydney, 15-19 March, 2004, Sydney (2004) [E3]
Co-authors Peter Gibson, Vicki Clifton
2004 Delahunty M, Fittock R, Murphy VE, Smith R, Zarzycki PK, Clifton VL, 'Metabolism of synthetic glucocortcoids used for the treatment of asthma by the human placenta', Conference of the Perinatal Society of Australia and New Zealand, Sydney, 15-19 March, 2004, Sydney (2004) [E3]
Co-authors Vicki Clifton, Roger Smith
2004 Murphy VE, Gibson PG, Kessell CG, Clifton VL, 'Asthma self-management education for pregnant women delivered in an antenatal clinic setting', Perinatal Scoiety of Australian and New Zealand 9th annual Congress, Adelaide, 13-16 March, Adealide (2004) [E3]
Co-authors Peter Gibson, Vicki Clifton
2003 Murphy VE, Gibson PG, Giles WB, Smith R, Clifton VL, 'A novel model for examining fetal growth restriction in human pregnancy', Reproductive Sciences, United States (2003) [C3]
Co-authors Vicki Clifton, Roger Smith, Peter Gibson
2003 Murphy VE, Johnson RF, Wang Y, Akinsanya K, Gibson PG, Smith R, Clifton VL, 'A proteomic analysis of maternal plasma, umbilical cord plasma and placenta in asthmatic and non-asthmatic pregnancies', Australian Society for Medical Research, National Scientific Conference, Glenelg, 22-24 Nov, 2003, Not Known (2003) [E3]
Co-authors Vicki Clifton, Roger Smith, Peter Gibson
2003 Murphy VE, Gibson PG, Giles WB, Smith R, Clifton VL, 'The effect of fetal gender on maternal inflammation and lung function in asthmatic pregnancies', Endocrine Society of Australia Annual Meeting, Melbourne 14-17 Sept, 2003, Melbourne (2003) [E3]
Co-authors Vicki Clifton, Roger Smith, Peter Gibson
2003 Scott NM, Osei-Kumah A, Murphy VE, Clifton VL, 'Are female fetuses more sensitive to the effects of inflammation than male fetuses?', Endocrine Society of Australian Annual Scientific Meeting, Melbourne, 14-17 Sept, 2003, Melbourne (2003) [E3]
Co-authors Vicki Clifton
2003 Murphy VE, Gibson PG, Giles WB, Smith R, Zarzycki PK, 'Placental and maternal inflammatory pathways in pregnancies complicated by asthma', Placenta, United Kingdom (2003) [C3]
Co-authors Peter Gibson, Roger Smith
2003 Clifton VL, Fittock R, Murphy VE, Smith R, 'Metabolism of semi-synthetic glucocorticoids by the human placenta', Placenta, United Kingdom (2003) [C3]
Co-authors Vicki Clifton, Roger Smith
2002 Murphy VE, Zakar T, Smith R, Giles WB, Kessell CG, Clifton VL, 'Maternal asthma affects fetal growth in a gender specific manner and is associated with reduced placental 11beta-HSD2 activity and altered sensitivity to cortisol', Reproductive Sciences, United States (2002) [C3]
Co-authors Roger Smith, Vicki Clifton
2002 Murphy VE, Gibson PG, Giles WB, Zakar T, Smith R, Kessell CG, Clifton VL, 'Sex-specific changes in placental function and fetal growth and development in pregnancies complicated by ashtma', Endocrine Society of Australia Annual Scientific Meeting, Adelaide, 22-25 Sept, 2002, Adelaide (2002) [E3]
Co-authors Peter Gibson, Roger Smith, Vicki Clifton
2001 Murphy VE, Zakar T, Gibson PG, Giles WB, Smith R, Clifton VL, 'Pleacental 11beta-HSD2 activity in asthmatic women', Reproductive sciences, United States (2001) [C3]
Co-authors Peter Gibson, Roger Smith, Vicki Clifton
2001 Murphy VE, Zakar T, Smith R, Giles WB, Gibson PG, Clifton VL, 'A potential mechnism for growth retardation in pregnancies complicated by asthma', Endocrine Society of Australia Annual Scientific Meeting, Gold Coast, 9-12 Sept, 2001, Gold Coast (2001) [E3]
Co-authors Peter Gibson, Roger Smith, Vicki Clifton
Show 58 more conferences
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Grants and Funding

Summary

Number of grants 35
Total funding $4,586,493

Click on a grant title below to expand the full details for that specific grant.


20157 grants / $1,598,988

The effect of asthma control during pregnancy on markers of airways inflammation and lung function in the offspring$1,083,354

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Joerg Mattes, Doctor Vanessa Murphy, Professor Peter Sly, Doctor Adam Collison, Professor Paul Robinson
Scheme Project Grant
Role Investigator
Funding Start 2015
Funding Finish 2015
GNo G1400050
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Optimising asthma management in pregnancy for optimal infant health$411,768

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Vanessa Murphy
Scheme Career Development Fellowships
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1400195
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

DVC(RI) Research Support for Career Development Fellow (CDF15)$60,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Vanessa Murphy
Scheme Special Project Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1500323
Type Of Funding Internal
Category INTE
UON Y

Viral infections in the BLT cohort in the first year of life$19,000

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team Professor Joerg Mattes, Doctor Vanessa Murphy, Doctor Adam Collison
Scheme Research Grant
Role Investigator
Funding Start 2015
Funding Finish 2015
GNo G1500671
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Lung function in early life for children with high asthma risk$17,048

Funding body: Rebecca L Cooper Medical Research Foundation Ltd

Funding body Rebecca L Cooper Medical Research Foundation Ltd
Project Team Professor Joerg Mattes, Doctor Vanessa Murphy, Doctor Adam Collison
Scheme Research Grant
Role Investigator
Funding Start 2015
Funding Finish 2015
GNo G1500704
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Lillian Roxon Asthma Australia Travel Grant$6,818

Funding body: Asthma Australia

Funding body Asthma Australia
Project Team Doctor Vanessa Murphy
Scheme Lillian Roxon Asthma Australia Travel Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1500772
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Perinatal Society of Australia and NewZealand, Melbourne Australia, 18-22 April 2015$1,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Vanessa Murphy
Scheme Travel Grant
Role Lead
Funding Start 2015
Funding Finish 2016
GNo G1500537
Type Of Funding Internal
Category INTE
UON Y

20142 grants / $1,649,904

The Breathing for Life Trial $1,647,904

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Vanessa Murphy, Conjoint Professor Peter Gibson, Emeritus Professor Michael Hensley, Professor Joerg Mattes, Professor Warwick Giles, Professor Michael Peek, Associate Professor Andrew Bisits, Associate Professor Leonie Callaway, Dr Kirsten McCaffery, Dr Helen Barrett
Scheme Project Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1300106
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

European Respiratory Society International Congress, Munich Germany, 6 - 10 September 2014$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Vanessa Murphy
Scheme Travel Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1400839
Type Of Funding Internal
Category INTE
UON Y

20135 grants / $83,810

Impact of fractional exhaled nitric oxide-based management of pregnancies with asthma on perinatal and infant outcomes $23,810

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team Doctor Vanessa Murphy, Emeritus Professor Michael Hensley
Scheme Research Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300782
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Inflammometry-based management of asthma in pregnancy for the prevention of preterm birth: the iMAP study$20,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Vanessa Murphy, Conjoint Professor Peter Gibson, Emeritus Professor Michael Hensley, Conjoint Professor Warwick Giles, Conjoint Associate Professor Andrew Bisits, Dr Kirsten McCaffery, Professor Paul Colditz, Professor Michael Peek
Scheme Near Miss Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300477
Type Of Funding Internal
Category INTE
UON Y

Inflammometry-based management of asthma in pregnancy for the prevention of preterm birth: the iMAP study$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Vanessa Murphy
Scheme Near Miss
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300695
Type Of Funding Internal
Category INTE
UON Y

Effect of better asthma management in pregnancy on antiviral responses, atopy and airways inflammation in early childhood$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Joerg Mattes, Conjoint Professor Peter Gibson, Doctor Vanessa Murphy
Scheme Near Miss Grant
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1300476
Type Of Funding Internal
Category INTE
UON Y

Effect of better asthma management in pregnancy on antiviral responses, atopy and airways inflammation in early childhood.$10,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Joerg Mattes, Conjoint Professor Peter Gibson, Doctor Vanessa Murphy
Scheme Near Miss
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1300694
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20122 grants / $58,076

Body plethysmograph respiratory function system$33,076

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Associate Professor Lisa Wood, Associate Professor Jodie Simpson, Doctor Katie Baines, Doctor Vanessa Murphy, Doctor Jeffrey Pretto, Emeritus Professor Michael Hensley, Ms Jenny Mackney
Scheme Equipment Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1100973
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

The Growing into Asthma Study: Wheezing prevalence and markers of airways inflammation in preschoolers born to mothers in asthma exacerbations in pregnancy$25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Joerg Mattes, Conjoint Professor Peter Gibson, Emeritus Professor Michael Hensley, Conjoint Associate Professor Bruce Whitehead, Doctor Vanessa Murphy
Scheme Project Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1200662
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20111 grants / $10,000

Lung Function (Spirometry) testing and sputum induction equipment - establishing 3 new clinical workstations. Medgraphics CPFS/d USB spirometer with breezesuite software (x3). Laptop computer (x3). Ul$10,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Katie Baines, Conjoint Professor Peter Wark, Doctor Vanessa Murphy
Scheme Equipment Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1100038
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20101 grants / $34,000

Real time PCR machine (Mastercycler ep realplex2 from Epprndorf) $34,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Doctor Robert Scott, Doctor Katie Baines
Scheme Equipment Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G1000056
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20092 grants / $38,300

Growing into asthma: A birth cohort study to investigate the prenatal and development origins of asthma$24,800

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Vanessa Murphy, Professor Joerg Mattes, Conjoint Professor Peter Gibson
Scheme Project Grant
Role Lead
Funding Start 2009
Funding Finish 2009
GNo G0189802
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Growing into asthma: a birth cohort study to investigate the prenatal and development origins of asthma$13,500

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Vanessa Murphy, Professor Joerg Mattes, Conjoint Professor Peter Gibson
Scheme Project Grant
Role Lead
Funding Start 2009
Funding Finish 2009
GNo G0190487
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20082 grants / $39,000

Becton Dickinson high throughout sampler for the FACSCanto II cytometry system$35,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Professor Phil Hansbro
Scheme Equipment Grant
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo G0188547
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

PULSE Education Prize$4,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Vanessa Murphy
Scheme PULSE Education Prize
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0188538
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20076 grants / $672,250

Viral infection and exacerbations of asthma during pregnancy: characteristics, mechanisms and consequences$447,750

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Vanessa Murphy
Scheme Project Grant
Role Lead
Funding Start 2007
Funding Finish 2007
GNo G0186434
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Viral infection and exacerbations of asthma during pregnancy: characteristics, mechanisms and consequences$137,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Vanessa Murphy
Scheme Training (Postdoctoral) Fellowships - Australian Part-time Research Fellowship
Role Lead
Funding Start 2007
Funding Finish 2007
GNo G0186778
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Nitric Oxide Monitoring System (NIOX)$45,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Conjoint Associate Professor Vicki Clifton, Conjoint Professor Warwick Giles, Emeritus Professor Michael Hensley, Doctor Vanessa Murphy, Conjoint Professor Peter Wark, Associate Professor Vanessa McDonald, Associate Professor Jodie Simpson, Conjoint Associate Professor Bruce Whitehead, Laureate Professor Paul Foster, Professor Phil Hansbro, Associate Professor Lisa Wood
Scheme Equipment Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0188193
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Hewlett Packard 7890 series gas chromatograph with accessories$20,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Lisa Wood, Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Doctor Vanessa Murphy, Laureate Professor Paul Foster, Professor Phil Hansbro, Conjoint Associate Professor Vicki Clifton, Professor Clare Collins, Conjoint Professor Wayne Smith, Professor John Attia
Scheme Equipment Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0188191
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Class II biohazard containment hood and carbon dioxide cell culture incubator$20,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Doctor Vanessa Murphy, Associate Professor Lisa Wood, Laureate Professor Paul Foster, Professor Phil Hansbro
Scheme Equipment Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0188192
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

American Thoracic Society Conference, San Francisco, 18/5/2007 - 23/5/2007$2,500

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Vanessa Murphy
Scheme Travel Grant
Role Lead
Funding Start 2007
Funding Finish 2007
GNo G0187767
Type Of Funding Internal
Category INTE
UON Y

20062 grants / $69,100

The relationship between eosinophilic inflammation, viral infection and severe asthma exacerbations during pregnancy$50,000

Funding body: Asthma Foundation of New South Wales

Funding body Asthma Foundation of New South Wales
Project Team Doctor Vanessa Murphy, Conjoint Associate Professor Vicki Clifton, Emeritus Professor Michael Hensley, Conjoint Professor Warwick Giles, Conjoint Professor Peter Gibson
Scheme Research Grant
Role Lead
Funding Start 2006
Funding Finish 2006
GNo G0186029
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

Viral infections and asthma exacerbations during pregnancy: characteristics, mechanisms and consequences$19,100

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Vanessa Murphy, Conjoint Associate Professor Vicki Clifton, Emeritus Professor Michael Hensley, Conjoint Professor Warwick Giles
Scheme Near Miss Grant
Role Lead
Funding Start 2006
Funding Finish 2006
GNo G0186061
Type Of Funding Internal
Category INTE
UON Y

20052 grants / $3,785

American Thoracic Society Conference, 20 to 25 May 2005$2,000

Funding body: Ian Potter Foundation

Funding body Ian Potter Foundation
Project Team Doctor Vanessa Murphy
Scheme Travel Grant
Role Lead
Funding Start 2005
Funding Finish 2005
GNo G0185081
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

American Thoracic Society Annual Scientific Conference, 20-25 May 2005$1,785

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Vanessa Murphy
Scheme Travel Grant
Role Lead
Funding Start 2005
Funding Finish 2005
GNo G0185399
Type Of Funding Internal
Category INTE
UON Y

20041 grants / $269,000

Respiratory Medicine$269,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Vanessa Murphy, Conjoint Professor Peter Gibson
Scheme Port Waratah Coal Service Post-Doctoral Fellowship
Role Lead
Funding Start 2004
Funding Finish 2004
GNo G0184012
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

20031 grants / $7,375

Identification of novel sex-specific factors derived from the human fetus.$7,375

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Vanessa Murphy
Scheme Travelling Award for Research Training
Role Lead
Funding Start 2003
Funding Finish 2003
GNo G0182186
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

20001 grants / $52,905

What causes preterm labour in asthmatic pregnancies? The role of placental 11beta-hydroxysteroid dehydrogenase type 2 and corticotropin releasing hormone$52,905

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Vanessa Murphy
Scheme Dora Lush Postgraduate Research Scholarship
Role Lead
Funding Start 2000
Funding Finish 2000
GNo G0181963
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y
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Research Supervision

Number of supervisions

Completed2
Current2

Total current UON EFTSL

PhD0.55

Current Supervision

Commenced Level of Study Research Title / Program / Supervisor Type
2015 PhD Assessing Acceptability of a Novel Antenatal Asthma Management Approach for Pregnant Women
General Medicine, Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2014 PhD To Determine the Effect of Reduced Asthma Exacerbations During Pregnancy on Markers of Airways Inflammation, Lung Function, and Antiviral Responses in the Offspring at Six Years of Age
General Medicine, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor

Past Supervision

Year Level of Study Research Title / Program / Supervisor Type
2014 Masters Asthma and Pregnancy: A Qualitative Descriptive Study of Midwives' Current Knowledge About Asthma in Pregnancy and Their Perceived Role in Antenatal Asthma Management in Australia
Midwifery, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2013 PhD Investigation of the Immune Mechanisms in Pregnancy and Asthma Leading to Increased Susceptibility and Disease Severity to Respiratory Virus Infections
General Medicine, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
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Dr Vanessa Murphy

Position

NHMRC Career Development Fellow
School of Medicine and Public Health
Faculty of Health and Medicine

Contact Details

Email vanessa.murphy@newcastle.edu.au
Phone (02) 40420141
Fax (02) 40420046

Office

Room HMRI West Wing Level 2
Building HMRI
Location Other

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