Profile Image

Staff Profile

Edit

Career Summary

Biography

I arrived at the University of Newcastle in 1998 to take up a part time teaching appointment and was promoted to Lecturer as of 1 Jan 2005. Since arriving at the University, as well as developing a teaching profile based on 200+ contact hours per annum, I have established myself as a researcher in the area of early male germ cell differentiation. I am now producing consistent output: I have coauthored 1 book chapter and 9 manuscripts in the last 4 years as well as 28 conference presentations.

I have presented my work nationally and internationally (American Society of Andrology, USA, Phoenix USA 2003, UK Environmental Mutagenesis Society & 3rd International Congress on Male Mediated Developmental Toxicity, Bradford UK, 2005). As an indication of the continual rise in my profile I recently chaired a session at a national meeting (Australian Society of Reproductive Biology). I currently serve on the Program Organising Committee for the 2007 annual meeting of the Society. I regularly review manuscripts for journals in both the Reproductive and Developmental biology fields.

Student outcomes: I have successfully cosupervised Honours students with 7/10 awarded First Class since 1999. I have successfully supervised, as sole supervisor, one PhD student to completion (R. Baleato, PhD awarded 2005) with a publication in a high impact journal. Dr Baleatos thesis was unanimously praised by the assessors as being of a high standard. I have cosupervised two PhD students to completion M Wade (PhD awarded 2004) and J Holt (PhD awarded 2006). Both students have generated significant publications from their PhD projects. I currently cosupervise one student who is generating a manuscript for submission.

I have been interviewed by various media (Fairfax 2004, 2006, NBN television 2005, The Medical Journal of Australia 2005). I have briefed government authorities on the neglected role of the male in the health of the offspring: Presentation to the Dept of Health and Aging, Office of Chemical Safety, Science Forum: Endocrine Disruptors: A Human Health Problem? Canberra, 2005.

Qualifications

  • PhD, University of New South Wales, 31/12/1996
  • Bachelor of Science, Flinders University
  • Bachelor of Science (Honours), Flinders University, 31/12/1987

Research

Research keywords

  • Gene Expression
  • Reproductive Biology
  • Signal Transduction
  • Spermatogenesis
  • Stem Cell Biology
  • Vitamin A metabolism

Research expertise

My experience is in gene expression and regulation, initially in breast cancer (Clarke et. al., 1990, 1991, Roman et. al., 1992, 1993). That work was focused on the role of retinoids in regulating gene expression in breast cancer and includes the initial description of the relationship between retinoid receptors and steroid hormone receptor status (Roman et. al., 1992). Retinoids are now part of the clinical arsenal employed in breast cancer treatment.

On the basis of my interest in retinoids, I became interested in retinoids and stem cell biology (Lane et. al, 1999). That work involved metabolic profiling of embryonic stem cells.

After a brief hiatus in the field of immunology, I arrived in Newcastle. My experience in the regulation of gene expression lead me to establish a number of techniques if use in Reproductive Science such as subtractive hybridisation and microarray analysis. Using these approaches and a number of other techniques we have cloned and characterised a number of genes (e.g. Curry et. al., 2004, Holt et. al., 2006).

In summary I have moved across fields, in the majority of cases employing new techniques to generate outcomes. I have now established a group focused on early germ cell differentiation. We have isolated spermatogonia and characterised gene expression in these cells. In particular we have sought to explain the arrested spermatogenesis found with vitamin A deficiency (Baleato et. al., 2005).

Along with Prof R. John Aitken and Dr Eileen McLaughlin, I represent the Newcastle hub of the ARC Centre of Excellence in Biotechnology and Development. Dr McLaughlin and I supervise a programme within the Centre that has the immortalisation of spermatogonial stem cells as its goal. I also cosupervise a PhD project with Prof David Jans (Monash) addressing the role DNA packaging in DNA damage. Prof Aitken and I collaborate on the role of environmental exposure in generating DNA damage in the male germ line (Aitken et. al., 2006, 2007).

Fields of Research

CodeDescriptionPercentage
060699Physiology Not Elsewhere Classified50
060100Biochemistry And Cell Biology35
110199Medical Biochemistry And Metabolomics Not Elsewhere Classified15

Memberships

Committee/Associations (relevant to research).

  • Program Organising Committee for 2007 - Australian Society for Reproductive Biology
  • Aust Society for Biochemistry & Molecular Biology
  • past member - Aust Socitey for Medical Research

Invitations

Science Forum: Endocrine Disruptors: A Human Health Problem?
Dept of Health and Aging, Office of Chemical Safety, Australia (Conference Presentation - non published.)
2005
Cytochrome P450 2E2 Mediates Acrylamide Damage to the Male Germ Line
Lorne Genome, Australia ( )
2006

Administrative

Administrative expertise

I coordinate 3 courses with all the associated administration that entails.

I have acted as chair of an informal Biology Discipline Curriculum Committee. The Committee developed and implemented the changes to the Biology curriculum detailed in the teaching statement. As part of the implementation I also act as informal timetabling officer for the Biology Discipline.

I was an active participant in the informal meetings within the then Faculty of Science and Mathematics that ultimately lead to the Early Career Researcher Proposal. I was one of the original signatories to that proposal, which lead to recognition and support of ECRs by the Faculty of Science and IT.

I served as the Early Career Researcher representative on the Faculty Research Committee of the Faculty of Science and IT for 12 months from February 2002.

I organised and chaired the 2002 ForefronT conference, showcasing the research of ECRs within the Faculty of Science and IT. The conference was attended by the VC. I presented at the 2003 conference.

I drafted, in collaboration with Dr. Michelle Adams, the Guidelines for Scientific Evaluation of Animal Ethics Applications by the FRC of the Faculty of Science and IT.

I served on the selection committee for two research appointments within the Reproductive Science group.

Teaching

Teaching keywords

  • Cellular Biotechnology
  • Molecular Biology

Teaching expertise

I am engaged in extensive teaching. I coordinate 3 courses of which ones is a core second year Biotech course (60+ students), one is the molecular lab skills course (80+ students) and one is a core 3rd year Biotech course (30+ students). I also teach into the 3rd year molecular biology course.

I believe students are engaged by inquiry-based learning. My teaching approach involves the use of innovative teaching techniques to encourage inquiry-based learning. I believe that I am achieving this in all my courses. My student evaluation of teaching scores and comments suggest students perceive me as being enthusiastic, approachable and someone who will explain difficult concepts to the students.

In general the students are motivated towards self-learning. One outcome is the students choose to do research placements and Honours with me and the outcome from that path is a graduate highly skilled in research. Students who do not go onto research have acquired life skills. In particular critical analysis and presentation skills are enhanced by the students exposure to my teaching.

Since my arrival at the University of Newcastle I have been extensively involved in curriculum design. I have generated or revised curriculum in at least one course per annum for the last eight years. I have introduced courses. In the last 2 years I have been the initiator of, and one of the driving forces behind, the extensive changes in the Biology curricula such that separate theoretical and practical courses are now taught. This separation has allowed for greater capacity, flexibility and a more focused learning experience. While it is too early for a complete evaluation all early feedback from students has been positive.

I have generated both problem-based learning and inquiry-based learning curriculum. I presented on Peer Evaluation in Groupwork at the UniServe Science Symposium (Oct 2004).

Edit

Publications

No publications.

Edit

Grants and Funding

Summary

Number of grants36
Total funding$20,744,602

For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (1 grants)

NucleoCounter SP100$14,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Laureate Professor John Aitken, Associate Professor Brett Nixon, Doctor Shaun Roman, Doctor Mark Baker, Doctor Geoffry De Iuliis, Doctor Lisa Mitchell, Doctor Matthew Jobling, Ms Zamira Gibb, Mr Nenad Naumovski
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$14,00020132013
GNo:G1201175

2012 (2 grants)

BMG SPECTROstar Nano$15,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Laureate Professor John Aitken, Professor Eileen McLaughlin, Ms Belinda Nixon, Doctor Shaun Roman, Doctor Mark Baker, Doctor Geoffry De Iuliis, Doctor Lisa Mitchell, Doctor Matthew Jobling
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$15,00020122012
GNo:G1100971

Ultrasonic Homogenizer System and -80 ÂșC Freezers for chemical and biological sample storage$10,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Adam McCluskey, Professor Eileen McLaughlin, Professor Peter Lewis, Ms Belinda Nixon, Doctor Shaun Roman, Doctor Jennette Sakoff, Doctor Ian Grainge
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020122012
GNo:G1100986

2011 (2 grants)

Chemical Biology$444,961
Funding Body: University of Newcastle

Eppendorf mastercycler pro with thermomixer comfort and 5430R centrifuge$15,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Eileen McLaughlin, Professor Peter Lewis, Professor Adam McCluskey, Conjoint Professor Keith Jones, Associate Professor Brett Nixon, Doctor Shaun Roman, Doctor Jennette Sakoff, Doctor Ian Grainge, Doctor Janet Holt, Doctor Xiao Yang
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$15,00020112011
GNo:G1100028

2010 (6 grants)

Sex Ratio and Sterility for Commercial animal production - round 5 Cluster$700,000
Funding Body: CSIRO - Commonwealth Scientific and Industrial Research Organisation

Project Team
Laureate Professor John Aitken, Professor Eileen McLaughlin, Doctor Shaun Roman
SchemeRole
National Research Flagship ClusterInvestigator
Total AmountFunding StartFunding Finish
$700,00020102013
GNo:G1000045

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$500,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Adam McCluskey, Laureate Professor John Aitken, Professor Paul Dastoor, Professor Phillip Robinson, Professor Eileen McLaughlin, Emeritus Professor Geoffrey Lawrance, Professor Marcel Maeder, Professor Hugh Dunstan, Doctor Shaun Roman, Associate Professor Rob Atkin, Doctor Clovia Holdsworth, Doctor Mark Baker, Doctor Nikki Verrills, Professor Gottfried Otting, Associate Professor Brett Nixon, Doctor Xiaojing Zhou, Ms Megan Chircop, Doctor Warwick Belcher
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF)Investigator
Total AmountFunding StartFunding Finish
$500,00020102010
GNo:G0190402

Laser microdissection microscopy system for cell and development biology$350,000
Funding Body: ARC (Australian Research Council)

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$280,000
Funding Body: University of Newcastle

Laser microdissection microscopy system for cell and development biology$215,000
Funding Body: University of Newcastle

Identifying vulnerable sites in the male genome$16,472
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Shaun Roman
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$16,47220102010
GNo:G0900133

2009 (4 grants)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)

Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000
Funding Body: ARC (Australian Research Council)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)

LAS-4000 Chemiluminescence imaging system$25,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Eileen McLaughlin, Laureate Professor John Aitken, Professor Peter Lewis, Associate Professor Brett Nixon, Doctor Shaun Roman
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020092009
GNo:G0189852

2008 (3 grants)

Centre for Biotechnology and Development$6,420,000
Funding Body: ARC (Australian Research Council)

Project Team
Laureate Professor John Aitken, Dr Gary Hime, Professor M Holland, Professor D Jans, Professor P Koopman, Dr Kate Loveland, Professor Eileen McLaughlin, Dr M O'Bryan, Doctor Shaun Roman, Assoc. Prof A Sinclair
SchemeRole
ARC Centres of ExcellenceInvestigator
Total AmountFunding StartFunding Finish
$6,420,00020082010
GNo:G0188624

Xenobiotics - ocidative stress in the mammalian ovary$362,625
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$362,62520082010
GNo:G0187620

Centre for Biotechnology and Development$297,273
Funding Body: NSW Department of State and Regional Development

Project Team
Laureate Professor John Aitken, Dr Gary Hime, Professor M Holland, Professor D Jans, Professor P Koopman, Dr Kate Loveland, Professor Eileen McLaughlin, Dr M O'Bryan, Doctor Shaun Roman, Assoc. Prof A Sinclair
SchemeRole
Centres of Excellence (Partner)Investigator
Total AmountFunding StartFunding Finish
$297,27320082010
GNo:G0189183

2007 (3 grants)

Centre for Biotechnology and Development.$96,220
Funding Body: NSW Department of State and Regional Development

Project Team
Laureate Professor John Aitken, Dr Kate Loveland, Professor P Koopman, Assoc. Prof A Sinclair, Professor D De Krester, Dr M O'Bryan, Dr Gary Hime, Professor D Jans, Doctor Shaun Roman, Professor Eileen McLaughlin, Professor C Goodnow, Professor M Holland
SchemeRole
Centres of Excellence (Partner)Investigator
Total AmountFunding StartFunding Finish
$96,22020072007
GNo:G0187937

Chemokines and spermatogenesis: roles of SDF-1 and CXCR-4 in the establishment of spermatogenesis$20,000
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Doctor Shaun Roman, Associate Professor Brett Nixon
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020072007
GNo:G0187197

Annual Scientific Meeting of the Society for Reproductive Biology, Christchurch NZ, 2/9/2007 - 5/9/2007$1,700
Funding Body: University of Newcastle

Project Team
Doctor Shaun Roman
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,70020072007
GNo:G0188087

2006 (3 grants)

PRC - Priority Research Centre for Reproductive Science$544,282
Funding Body: University of Newcastle

Project Team
Laureate Professor John Aitken, Professor Roger Smith, Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman, Conjoint Associate Professor Vicki Clifton, Conjoint Professor Warwick Giles, Associate Professor Jon Hirst, Conjoint Associate Professor Rick Nicholson, Conjoint Professor Ian Symonds
SchemeRole
Priority Research CentreInvestigator
Total AmountFunding StartFunding Finish
$544,28220062013
GNo:G0186945

Environmental impacts on female fertility and the menopause$17,273
Funding Body: Hunter Medical Research Institute

Project Team
Professor Eileen McLaughlin, Laureate Professor John Aitken, Doctor Shaun Roman
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$17,27320062006
GNo:G0186620

Elucidating the mechanics of transgenerational toxicity in the ageing male$10,000
Funding Body: University of Newcastle

Project Team
Doctor Shaun Roman, Professor John Attia, Dr Elizabeth Gillam
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020062006
GNo:G0186080

2005 (1 grants)

Gene profiling of the detoxifying enzymes in the male germ line$15,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Shaun Roman, Laureate Professor John Aitken
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,00020052005
GNo:G0184897

2004 (1 grants)

In vivo regulation of spermatogonial gene expression by Vitamin A$8,000
Funding Body: University of Newcastle

Project Team
Doctor Shaun Roman, Laureate Professor John Aitken
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$8,00020042004
GNo:G0183416

2003 (4 grants)

Centre for Biotechnology and Development.$9,458,900
Funding Body: ARC (Australian Research Council)

Project Team
Laureate Professor John Aitken, Dr Kate Loveland, Professor P Koopman, Assoc. Prof A Sinclair, Professor D De Krester, Dr M O'Bryan, Dr Gary Hime, Professor D Jans, Doctor Shaun Roman, Professor Eileen McLaughlin, Professor C Goodnow, Professor M Holland
SchemeRole
ARC Centres of ExcellenceInvestigator
Total AmountFunding StartFunding Finish
$9,458,90020032007
GNo:G0182214

The origin and control of oxidative stress in the placenta$29,666
Funding Body: University of Newcastle

Project Team
Laureate Professor John Aitken, Professor Roger Smith, Doctor Shaun Roman
SchemeRole
Multi-Year Project Grant ScholarshipInvestigator
Total AmountFunding StartFunding Finish
$29,66620032005
GNo:G0182393

Profiling germ cell gene expression during spermatogonial differentiation$5,000
Funding Body: University of Newcastle

Project Team
Doctor Shaun Roman, Professor Eileen McLaughlin
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$5,00020032003
GNo:G0182402

American Society of Andrology annual Meeting and associated workshops, Phoenix, Arizona, USA 26 March - 2 April, 2003$1,730
Funding Body: University of Newcastle

Project Team
Doctor Shaun Roman
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,73020032003
GNo:G0182915

2002 (2 grants)

Regulation of gene expression during spermatogonial development$8,000
Funding Body: University of Newcastle

Project Team
Doctor Shaun Roman
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$8,00020022002
GNo:G0181441

Characterisation of a non-genomic progesterone receptor in round spermatids$5,000
Funding Body: University of Newcastle

Project Team
Doctor Shaun Roman, Laureate Professor John Aitken
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$5,00020022002
GNo:G0181445

2001 (1 grants)

Interaction of Smad and Retinoid signalling pathways.$8,500
Funding Body: University of Newcastle

Project Team
Doctor Shaun Roman
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$8,50020012001
GNo:G0180093

2000 (1 grants)

Molecular basis of spermatogenesis$10,000
Funding Body: University of Newcastle

Project Team
Dr Keith Sutton, Laureate Professor John Aitken, Doctor Shaun Roman
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020002000
GNo:G0178860

1999 (2 grants)

Culture and genetic manipulation of male germ-line stem cells$11,000
Funding Body: University of Newcastle

Project Team
Doctor Shaun Roman
SchemeRole
New Staff GrantChief Investigator
Total AmountFunding StartFunding Finish
$11,00019991999
GNo:G0178424

Isolation of genetic markers to follow male germ cell progression from birth to spermatocyte.$9,000
Funding Body: University of Newcastle

Project Team
Doctor Shaun Roman
SchemeRole
Early Career Researcher GrantChief Investigator
Total AmountFunding StartFunding Finish
$9,00019991999
GNo:G0179147
Edit

Research Supervision

Number of current supervisions5
Total current UoN PhD EFTSL2.05

For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20132017PhD (Biological Sciences)Principal SupervisorConsequences of Chronic Exposure of the Male Germ Line to Xenobiotics
20102014PhD (Biological Sciences)Co-SupervisorInvestigating Membrane Trafficking Proteins and Their Potential Role During Fertilisation
20092013PhD (Biological Sciences)Principal SupervisorThe Consequences of Acrylaminde Exposure of the Male Germ Line
20092013PhD (Biological Sciences)Co-SupervisorPeroxisome Dynamics: Importance to the Restoration of Reactive Oxygen Species (ROS) Homeostasis During Plant Cell Regeneration
20072007Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorThe role of SDF-1/CXCR4 in spermatogenesis

Past Supervision

YearProgramSupervisor TypeResearch Title
2013PhD (Biological Sciences)Co-SupervisorInvestigation of the Transcription Complex in Acinetobacter baylyi ADP1 and the Identification of the Novel Small Acidic Transcription Factor AtfA
2013PhD (Biological Sciences)Co-SupervisorRegulation of the Transition from Gonocytes to Spermatogonia
2012PhD (Biological Sciences)Co-SupervisorXenobiotics; Effects on Female Fertility
2009PhD (Biological Sciences)Principal SupervisorThe Nature of Chromatin Packaging in Human Spermatozoa
2006PhD (Biological Sciences)Co-SupervisorGene Expression During Development of the Mammalian Ovarian Primordial Follicle
2005Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Sole SupervisorCytochrome P450 gene expression in the male germ line
2005PhD (Biological Sciences)Sole SupervisorThe Regulation of Gene Expression by Vitamin A during Mouse Spermatogenesis
2004Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorSOCS expression in the ovary
2004PHD Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorSperm Motility
2003Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorDNA damage and chromatin packaging in human spermatozoa
2003Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorCharacterisation of the sperm progesterone receptor
2001Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Principal SupervisorTGF-b signalling
2000Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorFoetal Organ Culture
2000Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorFactors Regulating Spermatogenesis
2000Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorOxidases in Aradopsis
1999Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorMammalian Sex Determination
1999Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorOxidases in Wallaby Spermatozoa
Edit

Dr Shaun Roman

Work Phone(02) 4921 6818
Fax(02) 4921 6923
Email
PositionSenior Lecturer
School of Environmental and Life Sciences
Faculty of Science and Information Technology
The University of Newcastle, Australia
Focus AreaBiological Sciences
Office
LS4-37,
Life Sciences,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/shaun-roman