Mrs Roseanne Peel

Mrs Roseanne Peel

Research Officer

Office of the PVC Health and Medicine (Public Health)

Career Summary

Biography

Ms Peel is a Registered Nurse and has completed a Graduate Certificate Intensive Care Nursing, qualified as an Authorised Nurse Immuniser, and has completed a Master of Public Health with Distiction (specialising in research methodology).

Ms Peel has a strong background in Intensive Care Nursing, Acute Stroke Nursing, Coronary Care Nursing and most recently qualified in Immunisation. Ms Peel has managed Case-Control Studies, Randomised Controlled Trials and Cohort Studies predominately with the School of Medicine and Public Health, University of Newcastle.

Roseanne has greater than ten years research project management experience and greater than thirty years nursing experience. Her current position involves the overall co-ordinating of a national multi-centre randomised controlled trial. She is also the longstanding Study Coordinator for the Hunter's Prospective Cohort Study - the Hunter Community Study, a Public Health and Health Services research resource that has attracted  collaborations nationally and internationally and has produced over 60 publications including high impact journals such as Nature.

Research Expertise
Research Research Assistant/Senior Research Assistant School of Medicine and Public Health, University of Newcastle, 2003-Present time Health Projects and Role: Study Manager Multi-Centre RCT: Australian Study for the Prevention through Immunisation of Cardiovascular Events (AUSPICE) Trial (Pneumococcal Vaccine versus Placebo), Centre for Clinical Epidemiology and Biostatistics (CCEB), University of Newcastle October, 2014-Present Time Investigator, Pilot RCT: Does zinc supplementation delay or prevent diabetes in pre-diabetic adults? Centre for Clinical Epidemiology and Biostatistics (CCEB), University of Newcastle 2011-Present Time Research Study Co-ordinator: Olfactory Stress Test(Alzheimer’s Disease), CCEB, University of Newcastle, July 2012- Present time Research Study Co-ordinator & Clinic Manager Cohort Study Hunter Community Cohort Study, CCEB, University of Newcastle: January 2007 – Present Time Research Assistant: Extending Treatments and Networks in Depression (xTEND) Study CCEB, University of Newcastle: April 2010 – December 2011 Research Study Co-ordinator: Media Dr. And Heart Failure Validation Studies Clinical Pharmacology, University of Newcastle: June 2011 –December 2011 Study Co-ordinator RCT: Cerebral Hypothermia in Ischaemic Lesion (CHIL) Study Acute Stroke Service, Hunter New England Health: March 2009 – November 2010 Study Co-ordinator RCT: Comprehensive Stroke Unit Study CCEB, University of Newcastle: January 2009 – November 2010 Study Co-ordinator Case-Control Study – Acute Coronary Syndrome and Cox 2 Inhibitors/NSAIDS , Clinical Pharmacology: 2004-2006 Research Assistant : Case-Control Study – Heart Failure and Cox 2 Inhibitors/NSAIDS, Clinical Pharmacology: August –Dec 2003 Multicentre Open Label Randomised Controlled Trial – “Nice” Study (Normoglycaemia In intensive Care Evaluation), John Hunter Hospital ICU Multicentre Randomised Double Blinded Clinical Trial- “Safe” Study (Saline versus Albumin Fluid Evaluation), Multicentre Randomised Double Blinded Clinical Trial- “Selfotel” Study (Drug trial in head injured patients in Intensive Care), John Hunter Hospital ICU

Teaching Expertise
Research role

Administrative Expertise
Research Role

Collaborations
Roseanne works with Professor John Attia and Dr Mark McEvoy and provides a supporting role in their research collaborations with students and academics within the University of Newcastle, other National Universities and International Universities.

Qualifications

  • Master of Public Health, University of Newcastle
  • Registered Nurse, NSW Nurses Registration Board
  • Graduate Certificate in Nursing (Intens Care Nurs), John Hunter Hospital

Keywords

  • Health Protection
  • Immunisation
  • Public Health
  • Research role only

Fields of Research

Code Description Percentage
111799 Public Health and Health Services not elsewhere classified 100
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Journal article (17 outputs)

Year Citation Altmetrics Link
2016 Islam MR, Attia J, Ali L, McEvoy M, Selim S, Sibbritt D, et al., 'Zinc supplementation for improving glucose handling in pre-diabetes: A double blind randomized placebo controlled pilot study', Diabetes Research and Clinical Practice, 115 39-46 (2016)

© 2016 Elsevier Ireland Ltd.Aims: There are a number of studies showing that zinc supplementation may improve glucose handling in people with established diabetes. We sought to i... [more]

© 2016 Elsevier Ireland Ltd.Aims: There are a number of studies showing that zinc supplementation may improve glucose handling in people with established diabetes. We sought to investigate whether this zinc-dependent improvement in glucose handling could potentially be harnessed to prevent the progression of pre-diabetes to diabetes. In this double-blind randomized placebo-controlled trial, we determined participants' fasting blood glucose levels, (FBG) and Homeostasis Model Assessment (HOMA) parameters (beta cell function, insulin sensitivity and insulin resistance) at baseline and after 6 months of zinc supplementation. Methods: The Bangladesh Institute of Health Sciences Hospital (BIHS) (Mirpur, Dhaka, Bangladesh) database was used to identify 224 patients with prediabetes, of whom 55 met the inclusion criteria and agreed to participate. The participants were randomized either to the intervention or control group using block randomization. The groups received either 30 mg zinc sulphate dispersible tablet or placebo, once daily for six months. Results: After six months, the intervention group significantly improved their FBG concentration compared to the placebo group (5.37 ± 0.20 mmol/L vs 5.69 ± 0.26, p < 0.001) as well as compared to their own baseline (5.37 ± 0.20 mmol/L vs 5.8 ± 0.09, p < 0.001). Beta cell function, insulin sensitivity and insulin resistance all showed a statistically significant improvement as well. Conclusion: To our knowledge this is the first trial to show an improvement in glucose handling using HOMA parameters in participants with prediabetes. Larger randomized controlled trials are warranted to confirm these findings and to explore clinical endpoints.

DOI 10.1016/j.diabres.2016.03.010
Co-authors Milton Hasnat, Mark Mcevoy, John Attia
2015 Chan JPL, Thalamuthu A, Oldmeadow C, Armstrong NJ, Holliday EG, McEvoy M, et al., 'Genetics of hand grip strength in mid to late life', Age, 37 1-10 (2015) [C1]

© 2015, American Aging Association.Hand grip strength (GS) is a predictor of mortality in older adults and is moderately to highly heritable, but no genetic variants have been co... [more]

© 2015, American Aging Association.Hand grip strength (GS) is a predictor of mortality in older adults and is moderately to highly heritable, but no genetic variants have been consistently identified. We aimed to identify single nucleotide polymorphisms (SNPs) associated with GS in middle-aged to older adults using a genome-wide association study (GWAS). GS was measured using handheld dynamometry in community-dwelling men and women aged 55¿85 from the Hunter Community Study (HCS, N = 2088) and the Sydney Memory and Ageing Study (Sydney MAS, N = 541). Genotyping was undertaken using Affymetrix microarrays with imputation to HapMap2. Analyses were performed using linear regression. No genome-wide significant results were observed in HCS nor were any of the top signals replicated in Sydney MAS. Gene-based analyses in HCS identified two significant genes (ZNF295, C2CD2), but these results were not replicated in Sydney MAS. One out of eight SNPs previously associated with GS, rs550942, located near the CNTF gene, was significantly associated with GS (p = 0.005) in the HCS cohort only. Study differences may explain the lack of consistent results between the studies, including the smaller sample size of the Sydney MAS cohort. Our modest sample size also had limited power to identify variants of small effect. Our results suggest that similar to various other complex traits, many genetic variants of small effect size may influence GS. Future GWAS using larger samples and consistent measures may prove more fruitful at identifying genetic contributors for GS in middle-aged to older adults.

DOI 10.1007/s11357-015-9745-5
Citations Web of Science - 1
Co-authors Liz Holliday, Christopher Oldmeadow, Rodney Scott, Mark Mcevoy, John Attia
2015 Vashum KP, McEvoy MA, Hancock SJ, Islam MR, Peel R, Attia JR, Milton AH, 'Prevalence of and associations with excessive daytime sleepiness in an Australian older population', Asia-Pacific Journal of Public Health, 27 NP2275-NP2284 (2015) [C1]

© 2013 APJPH.The aim of this research is to estimate the prevalence of excessive daytime sleepiness in an older population and associations with sociodemographic, health, and lif... [more]

© 2013 APJPH.The aim of this research is to estimate the prevalence of excessive daytime sleepiness in an older population and associations with sociodemographic, health, and lifestyle factors using a cross-sectional, population-based study. Participants were men (1560) and women (1759), aged 55 to 85 years, enrolled in the Hunter Community Study, a longitudinal study of aging. Measurements were self-reported questionnaires, biochemical measures, and clinical measures. Of the 3319 participants, 3053 participants completed the Epworth Sleepiness Scale questionnaire. The prevalence of excessive daytime sleepiness was 15.3% overall and this was higher in males. In adjusted multivariate analysis, gender, working full time, body mass index, high-density and low-density lipoprotein cholesterol, Center for Epidemiologic Studies-Depression scale score, and Kessler psychological distress score were associated with excessive daytime sleepiness. Given the high prevalence of excessive daytime sleepiness observed in this study, further investigation and/or interventions to reduce adverse health outcomes, especially in males is warranted.

DOI 10.1177/1010539513497783
Citations Scopus - 4
Co-authors Mark Mcevoy, Milton Hasnat, John Attia
2014 Holliday EG, Attia J, Hancock S, Koloski N, McEvoy M, Peel R, et al., 'Genome-wide association study identifies two novel genomic regions in irritable bowel syndrome', American Journal of Gastroenterology, 109 770-772 (2014) [C1]
DOI 10.1038/ajg.2014.56
Citations Scopus - 4Web of Science - 4
Co-authors John Attia, Mark Mcevoy, Nicholas Talley, Rodney Scott, Liz Holliday
2014 Moayyeri A, Hsu Y-H, Karasik D, Estrada K, Xiao S-M, Nielson C, et al., 'Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium', HUMAN MOLECULAR GENETICS, 23 3054-3068 (2014) [C1]
DOI 10.1093/hmg/ddt675
Citations Scopus - 24Web of Science - 21
Co-authors Rodney Scott, Liz Holliday, Christopher Oldmeadow, Mark Mcevoy, John Attia
2014 Handley TE, Hiles SA, Inder KJ, Kay-Lambkin FJ, Kelly BJ, Lewin TJ, et al., 'Predictors of Suicidal Ideation in Older People: A Decision Tree Analysis', AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 22 1325-1335 (2014) [C1]
DOI 10.1016/j.jagp.2013.05.009
Citations Scopus - 5Web of Science - 3
Co-authors John Attia, Mark Mcevoy, Brian Kelly, Kerry Inder, Terry Lewin, Frances Kaylambkin
2014 Islam MR, Attia J, Alauddin M, McEvoy M, McElduff P, Slater C, et al., 'Availability of arsenic in human milk in women and its correlation with arsenic in urine of breastfed children living in arsenic contaminated areas in Bangladesh.', Environmental Health: A Global Access Science Source, 13 1-10 (2014) [C1]
Co-authors Mark Mcevoy, John Attia, Catherine Deste, Milton Hasnat, Wayne Smith
2014 McEvoy M, Schofield P, Smith W, Agho K, Mangoni AA, Soiza RL, et al., 'Memory Impairment is Associated with Serum Methylarginines in Older Adults', CURRENT ALZHEIMER RESEARCH, 11 97-106 (2014) [C1]
Citations Scopus - 5Web of Science - 5
Co-authors Peter Schofield, Mark Mcevoy, John Attia, Wayne Smith
2014 Napthali K, Boyle M, Tran H, Schofield PW, Peel R, McEvoy M, et al., 'Thyroid antibodies, autoimmunity and cognitive decline: is there a population-based link?', Dement Geriatr Cogn Dis Extra, 4 140-146 (2014) [C1]
DOI 10.1159/000362716
Co-authors Peter Schofield, Christopher Oldmeadow, Mark Mcevoy, John Attia
2013 McEvoy MA, Schofield P, Smith W, Agho K, Mangoni AA, Soiza RL, et al., 'Serum methylarginines and incident depression in a cohort of older adults', Journal of Affective Disorders, 151 493-499 (2013) [C1]
DOI 10.1016/j.jad.2013.06.033
Citations Scopus - 6Web of Science - 6
Co-authors Kerry Inder, Mark Mcevoy, Wayne Smith, Brian Kelly, Peter Schofield, John Attia
2013 Islam MR, Arslan I, Attia J, McEvoy M, McElduff P, Basher A, et al., 'Is Serum Zinc Level Associated with Prediabetes and Diabetes?: A Cross-Sectional Study from Bangladesh', PLOS ONE, 8 (2013) [C1]
DOI 10.1371/journal.pone.0061776
Citations Scopus - 10Web of Science - 7
Co-authors John Attia, Mark Mcevoy, Milton Hasnat
2013 McEvoy MA, Schofield PW, Smith WT, Agho K, Mangoni AA, Soiza RL, et al., 'Serum Methylarginines and Spirometry-Measured Lung Function in Older Adults', PLOS ONE, 8 (2013) [C1]
DOI 10.1371/journal.pone.0058390
Citations Scopus - 2Web of Science - 1
Co-authors John Attia, Mark Mcevoy, Peter Schofield, Wayne Smith
2012 Suthers B, Hansbro PM, Thambar S, McEvoy MA, Peel R, Attia JR, 'Pneumococcal vaccination may induce anti-oxidized low-density lipoprotein antibodies that have potentially protective effects against cardiovascular disease', Vaccine, 30 3983-3985 (2012) [C1]
Citations Scopus - 6Web of Science - 8
Co-authors Philip Hansbro, Mark Mcevoy, John Attia
2012 Holliday EG, Maguire JM, Evans T-J, Koblar SA, Jannes J, Sturm J, et al., 'Common variants at 6p21.1 are associated with large artery atherosclerotic stroke', Nature Genetics, 44 1147-1153 (2012) [C1]
Citations Scopus - 65Web of Science - 63
Co-authors Mark Parsons, Wayne Smith, Jane Maguire, Rodney Scott, Lisa Lincz, Chris Levi, Liz Holliday, Christopher Oldmeadow, Mark Mcevoy, John Attia, Pablo Moscato
2012 Islam MR, Khan I, Hassan SMN, McEvoy MA, D'Este CA, Attia JR, et al., 'Association between type 2 diabetes and chronic arsenic exposure in drinking water: A cross sectional study in Bangladesh', Environmental Health, 11 1-8 (2012) [C1]
Citations Scopus - 28Web of Science - 9
Co-authors Mark Mcevoy, John Attia, Milton Hasnat, Catherine Deste
2011 McGettigan P, Lincz L, Attia JR, McElduff P, Bissett L, Peel R, et al., 'The risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors does not vary with polymorphisms in two regions of the cyclo-oxygenase-2 gene', British Journal of Clinical Pharmacology, 72 707-714 (2011) [C1]
DOI 10.1111/j.1365-2125.2011.03957.x
Citations Scopus - 6Web of Science - 7
Co-authors Lisa Lincz, John Attia, Mddah01
2010 McEvoy MA, Smith WT, D'Este CA, Duke JM, Peel R, Schofield PW, et al., 'Cohort Profile: The Hunter Community Study', International Journal of Epidemiology, 39 1452-1463 (2010) [C1]
DOI 10.1093/ije/dyp343
Citations Scopus - 67Web of Science - 64
Co-authors Peter Schofield, Mddah01, Mark Mcevoy, Wayne Smith, Julie Byles, Ben Ewald, Rodney Scott, Catherine Deste, John Attia
Show 14 more journal articles

Conference (4 outputs)

Year Citation Altmetrics Link
2011 Khan I, Hassan S, McEvoy MA, D'Este CA, Attia JR, Peel R, Hasnat MA, 'Association between type 2 diabetes and chronic arsenic exposure in Bangladesh', Epidemiology (2011) [E3]
Citations Web of Science - 2
Co-authors Milton Hasnat, John Attia, Mark Mcevoy, Catherine Deste
2009 McGettigan P, Peel R, Stokes BJ, Henderson KM, Whitaker DE, Henry D, 'What did 'safe' mean to prescribers of selective COX-2 inhibitors?', Basic & Clinical Pharmacology & Toxicology (2009) [E3]
DOI 10.1111/j.1742-7843.2009.00437.x
2009 Henry D, Lincz L, Attia JR, McElduff P, Bisset L, Peel R, et al., 'Polymorphisms in two regions of the cyclo-oxygenase-2 gene associated with variation in risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors', Basic & Clinical Pharmacology & Toxicology (2009) [E3]
DOI 10.1111/j.1742-7843.2009.00436.x
Co-authors Lisa Lincz, John Attia
2009 Henry D, Lincz L, Attia J, McElduff P, Bisset L, Peel R, et al., 'Polymorphisms in Two Regions of the Cyclo-Oxygenase-2 Gene Associated with Variation in Risk of Coronary Thrombosis with Cyclo-Oxygenase-2 Inhibitors', PHARMACOEPIDEMIOLOGY AND DRUG SAFETY (2009) [E3]
Co-authors Lisa Lincz, John Attia
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Mrs Roseanne Peel

Position

Research Officer
CCEB
Office of the PVC Health and Medicine
Faculty of Health and Medicine

Focus area

Public Health

Contact Details

Email roseanne.peel@newcastle.edu.au
Phone 40420523

Office

Room HMRI 4109-22
Building Hunter Medical Research Institute
Location Level 4 CCEB

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